The purpose of this study is to investigate the sleep habits, cervical health status, and the demand and preference for pillow products of different populations through data analysis. A total of 780 valid responses we...The purpose of this study is to investigate the sleep habits, cervical health status, and the demand and preference for pillow products of different populations through data analysis. A total of 780 valid responses were gathered via an online questionnaire to explore the sleep habits, cervical health conditions, and pillow product preferences of modern individuals. The study found that sleeping late and staying up late are common, and the use of electronic devices and caffeine consumption have a negative impact on sleep. Most respondents have cervical discomfort and have varying satisfaction with pillows, which shows their demand for personalized pillows. The machine learning model for predicting the demand of latex pillow was constructed and optimized to provide personalized pillow recommendation, aiming to improve sleep quality and provide market data for sleep product developers.展开更多
Chronic intermittent hypoxia is considered to play an important role in cardiovascular pathogenesis during the development of obstructive sleep apnea（OSA）.We used a well-described OSA rat model induced with simultan...Chronic intermittent hypoxia is considered to play an important role in cardiovascular pathogenesis during the development of obstructive sleep apnea（OSA）.We used a well-described OSA rat model induced with simultaneous intermittent hypoxia.Male Sprague Dawley rats were individually placed into plexiglass chambers with air pressure and components were electronically controlled.The rats were exposed to intermittent hypoxia 8 hours daily for 5weeks.The changes of cardiac structure and function were examined by ultrasound.The cardiac pathology,apoptosis,and fibrosis were analyzed by H＆E staining,TUNNEL assay,and picosirius staining,respectively.The expression of inflammation and fibrosis marker genes was analyzed by quantitative real-time PCR and Western blot.Chronic intermittent hypoxia/low pressure resulted in significant increase of left ventricular internal diameters（LVIDs）,endsystolic volume（ESV）,end-diastolic volume（EDV）,and blood lactate level and marked reduction in ejection fraction and fractional shortening.Chronic intermittent hypoxia increased TUNNEL-positive myocytes,disrupted normal arrangement of cardiac fibers,and increased Sirius stained collagen fibers.The expression levels of hypoxia induced factor（HIF）-l α,NF-κB,IL-6,and matrix metallopeptidase 2（MMP-2） were significantly increased in the heart of rats exposed to chronic intermittent hypoxia.In conclusion,the left ventricular function was adversely affected by chronic intermittent hypoxia,which is associated with increased expression of HIF-lα and NF-κB signaling molecules and development of cardiac inflammation,apoptosis and fibrosis.展开更多
A new algorithm for the detection of sleep spindles from human sleep EEG with surrogate data approach is presented. Surrogate data ap-proach is the state of the art technique for nonlinear spectral analysis. In this p...A new algorithm for the detection of sleep spindles from human sleep EEG with surrogate data approach is presented. Surrogate data ap-proach is the state of the art technique for nonlinear spectral analysis. In this paper, by developing autoregressive (AR) models on short segment of the EEG is described as a superposition of harmonic oscillating with damping and frequency in time. Sleep spindle events are detected, whenever the damping of one or more frequencies falls below a prede-fined threshold. Based on a surrogate data, a method was proposed to test the hypothesis that the original data were generated by a linear Gaussian process. This method was tested on human sleep EEG signal. The algorithm work well for the detection of sleep spindles and in addition the analysis reveals the alpha and beta band activities in EEG. The rigorous statistical framework proves essential in establishing these results.展开更多
By using a questionnaire survey method to understand and explore user needs, combined with the QFD-KANO model to quantify research results, and using the “Better Worse coefficient” statistical method, the survey res...By using a questionnaire survey method to understand and explore user needs, combined with the QFD-KANO model to quantify research results, and using the “Better Worse coefficient” statistical method, the survey results are transformed into design practices. In the design practice, technologies such as sensors, signal processing, and control systems were adopted to achieve precise recognition and intelligent control of snoring sounds. The test results show that the intelligent anti snoring sleep aid pillow can achieve a snoring recognition accuracy of 94%, with high reliability and stability.展开更多
针对深度休眠模式下电源备份系统的可靠性问题,提出一种结合故障树分析(Fault Tree Analysis,FTA)、容量衰减模型和蒙特卡洛仿真的分析方法。通过对典型5G基站的电源备份系统进行建模,评估不同休眠时长和温度条件下的系统可靠度。研究发...针对深度休眠模式下电源备份系统的可靠性问题,提出一种结合故障树分析(Fault Tree Analysis,FTA)、容量衰减模型和蒙特卡洛仿真的分析方法。通过对典型5G基站的电源备份系统进行建模,评估不同休眠时长和温度条件下的系统可靠度。研究发现,休眠时长与温度呈双因素耦合衰减效应,15 d为可靠度衰减速率拐点,高温环境会加速电池化学劣化。该量化评估框架可为电源备份系统的冗余设计与温度补偿策略提供工程优化依据。展开更多
文摘The purpose of this study is to investigate the sleep habits, cervical health status, and the demand and preference for pillow products of different populations through data analysis. A total of 780 valid responses were gathered via an online questionnaire to explore the sleep habits, cervical health conditions, and pillow product preferences of modern individuals. The study found that sleeping late and staying up late are common, and the use of electronic devices and caffeine consumption have a negative impact on sleep. Most respondents have cervical discomfort and have varying satisfaction with pillows, which shows their demand for personalized pillows. The machine learning model for predicting the demand of latex pillow was constructed and optimized to provide personalized pillow recommendation, aiming to improve sleep quality and provide market data for sleep product developers.
基金supported by Medical Key Talents Foundation of Jiangsu Province,China(No:904-KJXW18)by National Natural Science Youth Foundation of China(No.81300227 and No.81300159)
文摘Chronic intermittent hypoxia is considered to play an important role in cardiovascular pathogenesis during the development of obstructive sleep apnea（OSA）.We used a well-described OSA rat model induced with simultaneous intermittent hypoxia.Male Sprague Dawley rats were individually placed into plexiglass chambers with air pressure and components were electronically controlled.The rats were exposed to intermittent hypoxia 8 hours daily for 5weeks.The changes of cardiac structure and function were examined by ultrasound.The cardiac pathology,apoptosis,and fibrosis were analyzed by H＆E staining,TUNNEL assay,and picosirius staining,respectively.The expression of inflammation and fibrosis marker genes was analyzed by quantitative real-time PCR and Western blot.Chronic intermittent hypoxia/low pressure resulted in significant increase of left ventricular internal diameters（LVIDs）,endsystolic volume（ESV）,end-diastolic volume（EDV）,and blood lactate level and marked reduction in ejection fraction and fractional shortening.Chronic intermittent hypoxia increased TUNNEL-positive myocytes,disrupted normal arrangement of cardiac fibers,and increased Sirius stained collagen fibers.The expression levels of hypoxia induced factor（HIF）-l α,NF-κB,IL-6,and matrix metallopeptidase 2（MMP-2） were significantly increased in the heart of rats exposed to chronic intermittent hypoxia.In conclusion,the left ventricular function was adversely affected by chronic intermittent hypoxia,which is associated with increased expression of HIF-lα and NF-κB signaling molecules and development of cardiac inflammation,apoptosis and fibrosis.
文摘A new algorithm for the detection of sleep spindles from human sleep EEG with surrogate data approach is presented. Surrogate data ap-proach is the state of the art technique for nonlinear spectral analysis. In this paper, by developing autoregressive (AR) models on short segment of the EEG is described as a superposition of harmonic oscillating with damping and frequency in time. Sleep spindle events are detected, whenever the damping of one or more frequencies falls below a prede-fined threshold. Based on a surrogate data, a method was proposed to test the hypothesis that the original data were generated by a linear Gaussian process. This method was tested on human sleep EEG signal. The algorithm work well for the detection of sleep spindles and in addition the analysis reveals the alpha and beta band activities in EEG. The rigorous statistical framework proves essential in establishing these results.
文摘By using a questionnaire survey method to understand and explore user needs, combined with the QFD-KANO model to quantify research results, and using the “Better Worse coefficient” statistical method, the survey results are transformed into design practices. In the design practice, technologies such as sensors, signal processing, and control systems were adopted to achieve precise recognition and intelligent control of snoring sounds. The test results show that the intelligent anti snoring sleep aid pillow can achieve a snoring recognition accuracy of 94%, with high reliability and stability.
文摘针对深度休眠模式下电源备份系统的可靠性问题,提出一种结合故障树分析(Fault Tree Analysis,FTA)、容量衰减模型和蒙特卡洛仿真的分析方法。通过对典型5G基站的电源备份系统进行建模,评估不同休眠时长和温度条件下的系统可靠度。研究发现,休眠时长与温度呈双因素耦合衰减效应,15 d为可靠度衰减速率拐点,高温环境会加速电池化学劣化。该量化评估框架可为电源备份系统的冗余设计与温度补偿策略提供工程优化依据。
