The skinfold thickness of six items （facial skinfold, subscapular skinfold, suprailiac skinfold, biceps skinfold, triceps skinfold and calf skinfold） were measured in 465 Mulam adults （232 male and 233 female）. Th...The skinfold thickness of six items （facial skinfold, subscapular skinfold, suprailiac skinfold, biceps skinfold, triceps skinfold and calf skinfold） were measured in 465 Mulam adults （232 male and 233 female）. The results were as follows： （1） The average skinfold thickness are higher in female at every age group. （2） As a whole, the skinfold thickness in the body of trunk is bigger than that in the limbs in both male and female. The curves of biceps skinfold thickness and calf skinfold thickness of male doesn＇t fluctuate with age. Body fat percentage of male was the lowest in the 30s group. In female, the skinfold thickness of trunk and triceps increase with age while calf skinfold decreases. Body fat percentage of female increases with age but then decreases after 50 years old. （3） The mean vales of Mulam skinfold thickness are relatively low compared with Daur, Uzbek and Han nationality.展开更多
BACKGROUND The measurement of triceps skinfold(TSF)thickness serves as a noninvasive metric for evaluating subcutaneous fat distribution.Despite its clinical utility,the TSF thickness trajectories and their correlatio...BACKGROUND The measurement of triceps skinfold(TSF)thickness serves as a noninvasive metric for evaluating subcutaneous fat distribution.Despite its clinical utility,the TSF thickness trajectories and their correlation with overall mortality have not been thoroughly investigated.AIM To explore TSF thickness trajectories of Chinese adults and to examine their associations with all-cause mortality.METHODS This study encompassed a cohort of 14747 adults sourced from the China Health and Nutrition Survey.Latent class trajectory modeling was employed to identify distinct trajectories of TSF thickness.Subjects were classified into subgroups reflective of their respective TSF thickness trajectory.We utilized multivariate Cox regression analyses and mediation examinations to explore the link between TSF thickness trajectory and overall mortality,including contributory factors.RESULTS Upon adjustment for multiple confounding factors,we discerned that males in the‘Class 2:Thin-stable’and‘Class 3:Thin-moderate’TSF thickness trajectories exhibited a markedly reduced risk of mortality from all causes in comparison to the‘Class 1:Extremely thin’subgroup.In the mediation analyses,the Geriatric Nutritional Risk Index was found to be a partial intermediary in the relationship between TSF thickness trajectories and mortality.For females,a lower TSF thickness pattern was significantly predictive of elevated all-cause mortality risk exclusively within the non-elderly cohort.CONCLUSION In males and non-elderly females,lower TSF thickness trajectories are significantly predictive of heightened mortality risk,independent of single-point TSF thickness,body mass index,and waist circumference.展开更多
Background The present study evaluated the prognostic value of a new published joint index,the fat mass triceps skinfold-albumin index(TA)in patients with malignant tumors in at least two organs(MTT).Methods Patients ...Background The present study evaluated the prognostic value of a new published joint index,the fat mass triceps skinfold-albumin index(TA)in patients with malignant tumors in at least two organs(MTT).Methods Patients for this study were recruited prospectively as part of a multi-center cohort study titled"Investigation on Nutrition Status and its Clinical Outcome of Common Cancers in China"(INSCOC),conducted between January 2013 and December 2019.The study focused on MTT patients.The time-dependent receiver operating characteristic(ROC)curve analysis was employed to assess and compare the predictive accuracy of various nutritional and inflammatory indices,including the triceps skinfold-albumin index(TA),handgrip strength(HGS),midarm circumference(MAC),calf circumference(CC),systemic immune-inflammation index(SII),patient-generated subjective global assessment(PG-SGA),and malnutrition identified by the Global Leadership Initiative on Malnutrition(GLIM)criteria.Multiple Cox regression models were utilized to investigate the relationship between TA levels(categorized as continuous or normal vs.low)and overall survival(OS).Survival outcomes were graphically represented using Kaplan-Meier(K-M)curves.Results Five hundred five patients(290 male and 215 female)were included in this study.According to the cut-off of TA(women:49.9;men:45.6),347 patients(68.7%)and 158 patients(31.3%)were categorized as TA normal and TA low,respectively.TA low group had a higher incidence of vomiting than normal group(P=0.041).The TA low played the negative role in nutrition related index(BMI,MAC,CC,HGS,PG-SGA score and malnutrition diagnosed by GLIM)(all P<0.001).The curve of TA has been consistently above other curves(HGS,MAC,CC,SII and GLIM-defined malnutrition).After adjusted for age,gender,smoking,alcohol and other different variables,TA(normal vs low)is an indicator in predicting the survival of MTT patients in 4 models(model 1:HR=0.588,95%CI:0.432,0.801;model 2:HR=0.600,95%CI:0.435,0.827;model 3:HR=0.597,95%CI:0.433,0.823;model 4:HR=0.582,95%CI:0.380,0.892).Conclusion This study evaluated the prognostic index of the TA in MMT patients,which may direct the nutritional intervention strategies to improve the clinical outcomes,including overall survival.展开更多
基金Acknowledgments： This investigation is supported by the Natural Science Foundation of China （No. 30170482） and by Luocheng Anatomy County of Guangxi in China.
文摘The skinfold thickness of six items （facial skinfold, subscapular skinfold, suprailiac skinfold, biceps skinfold, triceps skinfold and calf skinfold） were measured in 465 Mulam adults （232 male and 233 female）. The results were as follows： （1） The average skinfold thickness are higher in female at every age group. （2） As a whole, the skinfold thickness in the body of trunk is bigger than that in the limbs in both male and female. The curves of biceps skinfold thickness and calf skinfold thickness of male doesn＇t fluctuate with age. Body fat percentage of male was the lowest in the 30s group. In female, the skinfold thickness of trunk and triceps increase with age while calf skinfold decreases. Body fat percentage of female increases with age but then decreases after 50 years old. （3） The mean vales of Mulam skinfold thickness are relatively low compared with Daur, Uzbek and Han nationality.
基金Supported by National High Level Hospital Clinical Research Funding,No.2022-PUMCH-B-015CAMS Innovation Fund for Medical Sciences,No.2021-1-12M-002+1 种基金CAMS Innovation Fund for Medical Sciences,No.2023-I2M-C&T-B-043Beijing Municipal Natural Science Foundation,No.M22014.
文摘BACKGROUND The measurement of triceps skinfold(TSF)thickness serves as a noninvasive metric for evaluating subcutaneous fat distribution.Despite its clinical utility,the TSF thickness trajectories and their correlation with overall mortality have not been thoroughly investigated.AIM To explore TSF thickness trajectories of Chinese adults and to examine their associations with all-cause mortality.METHODS This study encompassed a cohort of 14747 adults sourced from the China Health and Nutrition Survey.Latent class trajectory modeling was employed to identify distinct trajectories of TSF thickness.Subjects were classified into subgroups reflective of their respective TSF thickness trajectory.We utilized multivariate Cox regression analyses and mediation examinations to explore the link between TSF thickness trajectory and overall mortality,including contributory factors.RESULTS Upon adjustment for multiple confounding factors,we discerned that males in the‘Class 2:Thin-stable’and‘Class 3:Thin-moderate’TSF thickness trajectories exhibited a markedly reduced risk of mortality from all causes in comparison to the‘Class 1:Extremely thin’subgroup.In the mediation analyses,the Geriatric Nutritional Risk Index was found to be a partial intermediary in the relationship between TSF thickness trajectories and mortality.For females,a lower TSF thickness pattern was significantly predictive of elevated all-cause mortality risk exclusively within the non-elderly cohort.CONCLUSION In males and non-elderly females,lower TSF thickness trajectories are significantly predictive of heightened mortality risk,independent of single-point TSF thickness,body mass index,and waist circumference.
基金supported by Chongqing Science and Health Joint Medical Research Project(No.2024DBXM005)Talent Innovation Capability Training Program of Army Medical Center of PLA,Army Medical University(ZXZYTSLC05).
文摘Background The present study evaluated the prognostic value of a new published joint index,the fat mass triceps skinfold-albumin index(TA)in patients with malignant tumors in at least two organs(MTT).Methods Patients for this study were recruited prospectively as part of a multi-center cohort study titled"Investigation on Nutrition Status and its Clinical Outcome of Common Cancers in China"(INSCOC),conducted between January 2013 and December 2019.The study focused on MTT patients.The time-dependent receiver operating characteristic(ROC)curve analysis was employed to assess and compare the predictive accuracy of various nutritional and inflammatory indices,including the triceps skinfold-albumin index(TA),handgrip strength(HGS),midarm circumference(MAC),calf circumference(CC),systemic immune-inflammation index(SII),patient-generated subjective global assessment(PG-SGA),and malnutrition identified by the Global Leadership Initiative on Malnutrition(GLIM)criteria.Multiple Cox regression models were utilized to investigate the relationship between TA levels(categorized as continuous or normal vs.low)and overall survival(OS).Survival outcomes were graphically represented using Kaplan-Meier(K-M)curves.Results Five hundred five patients(290 male and 215 female)were included in this study.According to the cut-off of TA(women:49.9;men:45.6),347 patients(68.7%)and 158 patients(31.3%)were categorized as TA normal and TA low,respectively.TA low group had a higher incidence of vomiting than normal group(P=0.041).The TA low played the negative role in nutrition related index(BMI,MAC,CC,HGS,PG-SGA score and malnutrition diagnosed by GLIM)(all P<0.001).The curve of TA has been consistently above other curves(HGS,MAC,CC,SII and GLIM-defined malnutrition).After adjusted for age,gender,smoking,alcohol and other different variables,TA(normal vs low)is an indicator in predicting the survival of MTT patients in 4 models(model 1:HR=0.588,95%CI:0.432,0.801;model 2:HR=0.600,95%CI:0.435,0.827;model 3:HR=0.597,95%CI:0.433,0.823;model 4:HR=0.582,95%CI:0.380,0.892).Conclusion This study evaluated the prognostic index of the TA in MMT patients,which may direct the nutritional intervention strategies to improve the clinical outcomes,including overall survival.
