Investigating structural and hydroxyl group effects in electrooxidation of alcohols to value-added products by solid-acid electrocatalysts is essential for upgrading biomass alcohols.Herein,we report efficient electro...Investigating structural and hydroxyl group effects in electrooxidation of alcohols to value-added products by solid-acid electrocatalysts is essential for upgrading biomass alcohols.Herein,we report efficient electrocatalytic oxidations of saturated alcohols(C_(1)-C_(6))to selectively form formate using Ni Co hydroxide(Ni Co-OH)derived Ni Co_(2)O_(4)solid-acid electrocatalysts with balanced Lewis acid(LASs)and Brønsted acid sites(BASs).Thermal treatment transforms BASs-rich(89.6%)Ni Co-OH into Ni Co_(2)O_(4)with nearly equal distribution of LASs(53.1%)and BASs(46.9%)which synergistically promote adsorption and activation of OH-and alcohol molecules for enhanced oxidation activity.In contrast,BASs-enriched Ni Co-OH facilitates formation of higher valence metal sites,beneficial for water oxidation.The combined experimental studies and theoretical calculation imply the oxidation ability of C1-C6alcohols increases as increased number of hydroxyl groups and decreased HOMO-LUMO gaps:methanol(C_(1))<ethylene glycol(C_(2))<glycerol(C3)<meso-erythritol(C4)<xylitol(C5)<sorbitol(C6),while the formate selectivity shows the opposite trend from 100 to 80%.This study unveils synergistic roles of LASs and BASs,as well as hydroxyl group effect in electro-upgrading of alcohols using solid-acid electrocatalysts.展开更多
Tire-derived aggregate(TDA)is an engineered construction material produced from recycled scrap tires and is often used as a compressible layer overlying buried structures to reduce overburden loads.The potential ampli...Tire-derived aggregate(TDA)is an engineered construction material produced from recycled scrap tires and is often used as a compressible layer overlying buried structures to reduce overburden loads.The potential amplification of ground motion in a tunnel site is well understood,but the effect of the tunnel-TDA layer system on ground surface acceleration remains unclear.In this study,both linear and nonlinear dynamic analyses were performed to evaluate the contributions of a TDA layer to the acceleration amplification at the ground surface.The numerical model was calibrated using recorded data from a shaking table test and validated against the literature results,followed by extensive parametric studies.The mechanical and geometrical parameters investigated for the TDA layer included damping ratio,density,Young’s modulus,width,thickness,and depth.The predominant frequency and intensity level of input motions were also investigated.This study showed that the presence of the TDA layer provided an additional acceleration amplification effect.The amplification was more pronounced in areas above the tunnel,particularly for the wider and shallower TDA layer subjected to high frequency and low intensity input motions.展开更多
Background Goat milk is increasingly recognized for high digestibility and a distinctive compositional profile.Protein acetylation,an important post-translational modification,regulates biosynthetic and metabolic path...Background Goat milk is increasingly recognized for high digestibility and a distinctive compositional profile.Protein acetylation,an important post-translational modification,regulates biosynthetic and metabolic pathways.This study aimed to identify critical acetylated proteins and specific modification sites involved in milk production and component synthesis in dairy goats,thereby elucidating the molecular mechanisms of lactation.We performed a comparative TMT-based acetylomic and proteomic analysis of mammary tissues from Saanen dairy goats during peak lactation and the dry period using LC–MS/MS.A candidate acetylation site was further investigated in goat mammary epithelial cells(GMECs)through site-directed mutagenesis and lipid metabolic assays,establishing functional links between acetylation and mammary lipid metabolism and providing a foundation for molecular strategies to improve milk quality and yield.Results We established a comprehensive mammary acetylome,identifying 862 significantly acetylated proteins and 2,028 modification sites across the two physiological phases.Differentially acetylated proteins were predominantly localized to the cytoplasm(39.98%).From these,54 key acetylated proteins,including MTOR,BCAT2,QARS1,GOT1,GOT2,BDH1,ACSS1,STAT5B,FABP5,and GPAM were prioritized as candidates involved in milk protein synthesis,milk fat synthesis,lactose synthesis,and other lactation-related processes.Among them,β-hydroxybutyrate dehydrogenase 1(BDH1)acetylation was characterized in detail.Members of the HDAC family were identified as primary regulators mediating BDH1 deacetylation.BDH1 acetylation promoted lipid droplet formation and triglyceride synthesis in GMECs.At the transcriptional level,BDH1 acetylation upregulated LXRα,ACSL1 and SCD1,whereas deacetylation downregulated SCD1,FASN,and ACSL1.Notably,BDH1 acetylation/deacetylation significantly reduced SREBP1 expression,linking this modification to coordinated control of lipogenic gene networks.Conclusions This study established,for the first time,the comprehensive acetylome of mammary gland tissues in dairy goats,revealing a substantial number of differentially acetylated proteins and modification sites.We demonstrate that acetylation of BDH1 regulated by HDACs promotes lipid droplet biogenesis and triglyceride synthesis in GMECs through transcriptional modulation of key lipogenic genes and suppression of SREBP1.These findings provide mechanistic insights into the post-translational regulation of mammary lipid metabolism and offer molecular targets for future genetic and nutritional strategies aimed at enhancing milk quality and yield in dairy goats.展开更多
Methanol steam reforming(MSR)represents a promising route for hydrogen production,leveraging the high energy density and liquid-phase storage advantages of methanol.Copper-based catalysts have become indispensable for...Methanol steam reforming(MSR)represents a promising route for hydrogen production,leveraging the high energy density and liquid-phase storage advantages of methanol.Copper-based catalysts have become indispensable for MSR due to their cost-effectiveness,exceptional catalytic activity,and tunable selectivity.However,persistent challenges such as thermal sintering,undesirable CO byproduct formation,diminished low-temperature reactivity,and long-term catalyst deactivation limit their broad industrial deployment.This review comprehensively examines the mechanistic pathways of MSR over Cu-based catalysts,with particular focus on differentiating catalyst formulations optimized for high-temperature(>200°C)versus low-temperature(<200°C)operation.It highlights the decisive influence of Cu nanoparticle size,electronic structure,and crystal structure on catalytic performance.Cutting-edge design strategies,including multi-element engineering,innovative synthesis techniques,and deactivation mitigation,are critically evaluated to elucidate mechanistic connections between atomic-scale structure and catalytic performance enhancement.Finally,industrial applications of commercial Cu/ZnO/Al_(2)O_(3)variants and their scalability challenges are discussed,alongside prospective strategies for catalyst innovation and engineering to advance next-generation hydrogen production.展开更多
Petroleum leakage is a major groundwater contamination source,with chemical composition of water soluble fractions(WSFs)from diverse oil sources significantly impacting groundwater quality and source identification.Th...Petroleum leakage is a major groundwater contamination source,with chemical composition of water soluble fractions(WSFs)from diverse oil sources significantly impacting groundwater quality and source identification.The aim of this study was to assess impact of 15 diverse oils on groundwater quality and environmental forensics based on oil-water equilibrium experiments.Our results indicate that contamination of groundwater by gasoline and naphtha is primarily attributed to volatile hydrocarbons,while pollution from diesel,kerosene,and crude oil is predominantly from non-hydrocarbons.Rapid determination of the extent of non-hydrocarbon pollution in WSFs was achieved through a new quantitative index.Gasoline and naphtha exhibited the highest groundwater contamination potential while kerosene and light crude oils were also likely to cause groundwater contamina-tion.Although volatile hydrocarbons in the WSFs of diesel and jet fuel do not easily exceed current regulatory standards,unregulated non-hydrocarbons may pose a more severe contamination risk to groundwater.Notably,the presence of significant benzene and toluene,hydrogenation and alkylation products(e.g.,C4-C5 alkylben-zenes,alkylindenes,alkyltetralins,and dihydro-indenes),cycloalkanes in WSFs can effectively be utilized for preliminary source identification of light distillates,middle distillates,and crude oils,respectively.展开更多
Endogenous hydrogen systems,consisting of metal–organic coordination catalysts and alcohols,have been widely applied for the transfer hydrogenation(TH)of biomass-derived carbonyl compounds in recent years.Metal-organ...Endogenous hydrogen systems,consisting of metal–organic coordination catalysts and alcohols,have been widely applied for the transfer hydrogenation(TH)of biomass-derived carbonyl compounds in recent years.Metal-organic coordination catalysts showed satisfactory ability of TH in the secondary alcohols,but most of them could not effectively employ the cheaper primary alcohols as hydrogen donors.Furthermore,they commonly contained high metal contents,which also led to low catalytic efficiency in significant measure.In this work,we constructed a novel magnesium single-atom catalyst(Mg-NC)with merely 0.37 wt%Mg by means of a combined self-assembly and pyrolysis strategy.The characterization results indicated that Mg was atomically dispersed and it was coordinated with four pyridinic-N in Mg-NC.Due to the obvious electron transfer from Mg to its coordinated pyridinic-N,Mg–N_(4)active centers displayed high Lewis acid-base strength with abundant content,which brought remarkable catalytic activity.When Mg-NC was used for the TH of 5-hydroxymethylfurfural(HMF)in ethanol(EtOH),2,5-bis(hydroxymethyl)furan(BHMF)yield was up to 96.3%with high productivity of 19.85 molBHMF mol_(Mg)^(−1)h^(−1)at 150°C for 5 h.More interestingly,the process of TH over Mg-NC in EtOH was proved to proceed via the hydrogen radical mechanism.Additionally,Mg-NC exhibited powerful catalytic universality;it could not only utilize other primary alcohols(such as n-propanol and n-butanol)as hydrogen donors,but also catalyze the TH of other carbonyl compounds(such as furfural,5-methylfurfural,benzaldehyde,cyclohexanone,and levulinic acid).Overall,this work offered some important clues and references to reinforce the hydrogen-supplying ability of primary alcohols in the TH of various biomass-derived carbonyl compounds to high-value fine chemicals.展开更多
If you're tired of megacities that feel like nothing but glass,steel,and constant rush,Guangzhou moves at its own pace.Here,a 19th-century ancestral hall stands next to a 600-meter tower,and the day begins with te...If you're tired of megacities that feel like nothing but glass,steel,and constant rush,Guangzhou moves at its own pace.Here,a 19th-century ancestral hall stands next to a 600-meter tower,and the day begins with tea and delicate steamed treats instead of coffee.展开更多
Objectives:Phosphodiesterase 1A(PDE1A)regulates intracellular cyclic nucleotide signaling and has been implicated in tumor progression,but its clinical relevance and functional role in epithelial ovarian cancer(EOC),p...Objectives:Phosphodiesterase 1A(PDE1A)regulates intracellular cyclic nucleotide signaling and has been implicated in tumor progression,but its clinical relevance and functional role in epithelial ovarian cancer(EOC),particularly in relation to the response to platinum remain unclear.This study aimed to evaluate the clinical significance of PDE1A in EOG and to clarify its functional role in tumor progression and response to platinum-based chemotherapy.Methods:PDE1A mRNA and protein levels were analyzed using public databases,RNA sequencing,and immunohistochemistry.Correlations between PDE1A expression,clinicopathological features,and prognosis were assessed.Functional roles were investigated in ovarian cancer cell lines.Results:PDE1A was significantly overexpressed in EOC tissues compared with that in normal ovarian epithelial tissues.Overexpression correlated with advanced International Federation of Gynecology and Obstetrics(FIGO)stage,poor tumor grade,and reduced response to platinum-based chemotherapy.High PDE1A levels were linked to worse disease-free survival and overall survival,and multivariate analysis confirmed PDE1A as an independent prognostic factor.To elucidate its functional role,we performed in vitro experiments showing that PDE1A knockdown suppressed cell proliferation and colony formation,induced G1 arrest,and downregulatedβ-catenin signaling with reduced cyclin D1 and c-Myc expression.Notably,these inhibitory effects were partially rescued by lithium chloride(LiCl),a Wingless-related integration site(Wnt)/β-catenin activator.Conclusions:In conclusion,our findings identify PDE1A as a Wnt/β-catenin-linked biomarker of tumor progression and platinum resistance in EOC and provide a biological rationale for further investigation of PDE1A-targeted strategies in preclinical models.展开更多
Co-free Li-rich Li_(1.2)Ni_(0.2)Mn_(0.6)O_(2)(LR)cathode shows the highest working capacity that can be applied to high-energy density Li-ion batteries(LIBs).However,poor cycle stability and voltage decay caused by ph...Co-free Li-rich Li_(1.2)Ni_(0.2)Mn_(0.6)O_(2)(LR)cathode shows the highest working capacity that can be applied to high-energy density Li-ion batteries(LIBs).However,poor cycle stability and voltage decay caused by phase transition are always hindering its further development.Herein,a novel medium-entropy Li-rich Mn-based cathode material(LRMEF)was synthesized via a simple sol-gel method.The introduction of multivalent ions(Al^(3+)/Cu^(2+)doping at Mn sites and F−doping at O sites)effectively mitigates the Jahn-Teller distortion of Mn ions and suppresses oxygen release.High-angle annular dark-field scanning transmission electron microscopy(HAADF-STEM)images confirm that this synergistic doping strategy induces the in-situ formation of an approximately 3 nm-thick spinel surface layer,which significantly enhances structural stability and ion diffusion kinetics.Besides,a series of in-situ/ex-situ characterization methods and density functional theory(DFT)calculations have been carried out to fundamentally shed light on the optimized structure-activity relationship and reaction mechanism.As a result,the LR material with entropy regulation and anion doping exhibits excellent cycling stability(189.2 mAh g^(−1)at 1 C with 84%capacity retention after 300 cycles),rate performance(164.1 mAh g^(−1)at 5 C),and voltage retention(82.7%at 1 C after 300 cycles),demonstrating great application prospects in future high-energy-density LIBs.展开更多
Large-scale CO_(2)emissions have exacerbated the greenhouse effect,reinforcing the critical need for efficient CO_(2)mitigation methods.Plasma-catalytic technology enables CO_(2)conversion under mild conditions,especi...Large-scale CO_(2)emissions have exacerbated the greenhouse effect,reinforcing the critical need for efficient CO_(2)mitigation methods.Plasma-catalytic technology enables CO_(2)conversion under mild conditions,especially for CO_(2)methanation(the Sabatier reaction),which has attracted significant attention due to its economic benefits and the potential for safe energy transportation via existing natural gas pipelines.The development of high-performance CO_(2)methanation catalysts remains an ongoing and long-term objective,and there is a lack of adequate in-situ characterization techniques to investigate the mechanisms.This study focuses on the Ni/La_(2)O_(3)(LN)catalyst and introduces two CO_(2)activation strategies through F and Na modifications:the Ni-Ov-Ni site activation with electron transfer from Ni0 under low-power conditions and basic site activation under high-power conditions.The LN-NaF catalysts enhance CO_(2)methanation activity across the entire power range compared to LN,achieving a CO_(2)conversion of 86.3%and CH4 selectivity of 99.4%.Additionally,LN-F(h)reaches a CH4 yield 4.15 times higher than that of LN at low power.Furthermore,in-situ diffuse reflectance infrared Fourier transform(DRIFT)spectroscopy with a self-made reactor are performed under plasma-catalytic conditions to reveal the CO_(2)adsorption and conversion mechanisms,indicating that different dopants(F,Na,and NaF)exhibit promoting effects on different intermediates,resulting in variations in CO_(2)methanation activity.This study provides valuable insights for improving catalyst performance and a thorough comprehension of mechanisms in CO_(2)methanation.展开更多
Shorebirds migrate long-distances along the East Asian-Australasian Flyway(EAAF),exhibiting distinct spatiotemporal fluctuations in population dynamics.Because of habitat degradation and population declines at key sto...Shorebirds migrate long-distances along the East Asian-Australasian Flyway(EAAF),exhibiting distinct spatiotemporal fluctuations in population dynamics.Because of habitat degradation and population declines at key stopover sites along the EAAF,the South Korea's coastal wetlands have gained increasing attention for their ecological value.This study analyzed the shorebird population dynamics across 35 coastal wetlands in South Korea from 2016 to 2024 using data from the National Marine Ecosystem Monitoring Program.For the timeseries analysis,we employed three indicators:seasonal chan ges in abundance,short-term fluctuations(Fi),and long-term trends,assessed using the TRends and Indices for Monitoring data(TRIM)model.Abundance,species richness,and Shannon diversity indices were assessed across the regions during spring and autumn.The TRIM results revealed significant population increases in both seasons("Strong increase"in spring and"Moderate increase"in autumn).Species-level trends indicated notable increases in large-bodied shorebirds,including globally threatened species such as the Far Eastern Curlew(Numenius madagascariensis).Eurasian Curlew(N.arquata),and Eurasian Oystercatcher(Haematopus ostralegus),whereas other species showed variable responses.The Yellow Sea region(Gyeonggi,Chungcheong,and Western Jeolla)showed high biodiversity indices in spring,which may be associated with time-minimization strategies,whereas autumn patterns were characterized by more flexible and selective stopover use,possibly related to energy-minimization strategies.The East Coast and Jeju regions showed the lowest biodiversity indices.Furthermore,community-level analyses using Non-metric Multidimensional Scaling(NMDS)and PERMANOVA revealed distinct clustering of bird assemblages by macro-region and season,confirming significant spatial differentiation in community composition.These findings contrast with the broader declining trends reported across the EAAF and suggest that South Korea's coastal wetlands may serve as stable alternative stopover habitats,potentially supporting the redistribution or recovery of some species.This study highlights the importance of transboundary cooperation and region-specific habitat management that reflects local ecological contexts for effective conservation.展开更多
Hospital wastewater contains complex pollutants,including residual organic dyes and antibiotic-resistant pathogens,posing severe risks to ecosystems and human health.Conventional adsorbents,constrained by monopolar fu...Hospital wastewater contains complex pollutants,including residual organic dyes and antibiotic-resistant pathogens,posing severe risks to ecosystems and human health.Conventional adsorbents,constrained by monopolar functional groups and limited surface sites,fail to remove both pollutants simultaneously.Here,we report an intelligent responsive polyurethane microsphere adsorbent doped with diallyl dimethylammonium chloride modified carbon nanotubes,termed as PUCD microspheres.The PUCD integrates bipolar adsorption sites,tunable micrometer-scale pores,and a near-infrared(NIR)-triggered in situ capture mechanism within a single platform,which achieves up to 98.3%dye removal,maintains strong adsorption performance across a wide pH range and retains 83.3%efficiency for rhodamine B after five cycles.Notably,the PUCD employs a temperature-responsive phase transition:under NIR irradiation,the microspheres undergo shrinkage,reducing the pore size to generate a‘polymer trap',enabling in situ capture of bacteria with>99%efficiencies for both Staphylococcus aureus and Escherichia coli.By immobilizing live bacteria,the PUCD microspheres substantially reduces the risk of pathogen desorption and toxin release.This promising platform offers a safe,efficient,and single-stage strategy for hospital wastewater purification,enabling the simultaneous elimination of dyes and pathogenic bacteria.展开更多
At 11:00 p.m. on January 13, 2026, floodlights illuminated the launch pad at the Hainan Commercial Space Launch Site in Wenchang,south China’s Hainan Province. A Long March-8A (CZ-8A) carrier rocket lifted off with a...At 11:00 p.m. on January 13, 2026, floodlights illuminated the launch pad at the Hainan Commercial Space Launch Site in Wenchang,south China’s Hainan Province. A Long March-8A (CZ-8A) carrier rocket lifted off with a steady roar, its exhaust lighting up the night sky as it delivered a satellite into its designated orbit.The development of China’s first commercial space launch site has been striking. Since its inaugural launch in2024, it has completed 11 missions in less than 14 months—each a success.展开更多
The return capsule of the Shenzhou-20 spaceship,carrying no astronauts,touched down at the Dongfeng landing site in north China’s Inner Mongolia Autonomous Region at 9:34 a.m.(Beijing Time)on January 19,according to ...The return capsule of the Shenzhou-20 spaceship,carrying no astronauts,touched down at the Dongfeng landing site in north China’s Inner Mongolia Autonomous Region at 9:34 a.m.(Beijing Time)on January 19,according to the China Manned Space Agency(CMSA).展开更多
The pervasive accumulation of plastic waste exacerbates environmental degradation and undermines resource circularity.Selective thermal catalysis emerges as a transformative pathway for valorizing waste plastics into ...The pervasive accumulation of plastic waste exacerbates environmental degradation and undermines resource circularity.Selective thermal catalysis emerges as a transformative pathway for valorizing waste plastics into value-added chemicals,yet persistent challenges in catalytic activity and product selectivity demand systematic resolution.This review decodes cutting-edge advances in thermal depolymerization by converging two critical dimensions:atomic-scale active site engineering-where rational design of coordination features and interfacial architectures regulates C-C cleavage energetics and intermediate adsorption-and macromolecular-scale manipulation of polymer transient states-leveraging nanoconfinement effects,chain folding dynamics,and thermal fragmentation to accelerate conversion kinetics.We further highlight breakthroughs in operando char-acterization techniques that resolve time-evolving reaction coordinates across catalytic systems.By establishing multiscale structure-activity relationships linking catalyst configurations to polymer dynamics,this analysis derives design paradigms for next-generation upcycling systems.These principles enable economically viable,industrially scalable plastic valorization while charting a strategic trajectory toward carbon-circular economies.展开更多
在医疗技术日新月异的当下,手术已成为众多疾病治疗的关键手段。然而,手术并非毫无风险,手术部位感染(Surgical Site Infection,SSI)作为术后常见并发症之一。它不仅可能使患者住院时间延长、医疗费用增加,还可能影响手术效果,甚至对患...在医疗技术日新月异的当下,手术已成为众多疾病治疗的关键手段。然而,手术并非毫无风险,手术部位感染(Surgical Site Infection,SSI)作为术后常见并发症之一。它不仅可能使患者住院时间延长、医疗费用增加,还可能影响手术效果,甚至对患者的生命安全构成威胁。展开更多
Developing advanced electrocatalysts to convert CO_(2) into liquid fuels such as C_(2)H_(5)OH is critical for utilizing intermittent renewable energy.The formation of C_(2)H_(5)OH,however,is generally less favored com...Developing advanced electrocatalysts to convert CO_(2) into liquid fuels such as C_(2)H_(5)OH is critical for utilizing intermittent renewable energy.The formation of C_(2)H_(5)OH,however,is generally less favored compared with the other hydrocarbon products from Cu-based electrocatalysts.In this work,an alkanethiolmodified Cu_(2)O nanowire array(OTT-Cu_(2)O) was constructed with asymmetric Cu sites consisting of paired Cu-O and Cu-S motifs to overcome previous limitations of C_(2)H_(5)OH electrosynthesis via CO_(2)RR pathway.This catalyst achieves a high Faradaic efficiency of 45 % for CO_(2)-to-C_(2)H_(5)OH conversion at 300 m A/cm^(2),representing a more than two-fold enhancement over the Cu_(2)O electrode.Mechanistic investigations reveal that the Cu-S site exhibits distinct C-binding capability that stabilizes key intermediates(^(*)OCH_(2) and ^(*)CO),in contrast to the O-affinitive Cu-O site.The asymmetric S-Cu-O configuration promotes thermodynamically favorable asymmetric C-C coupling between ^(*)CO and ^(*)OCH_(2),forming the critical CO-OCH_(2) intermediate and facilitating C_(2)H_(5)OH production,as opposed to symmetric O-Cu-O sites that mainly generate HCOOH.This work offers an effective strategy for designing multi-active-site catalysts toward highly selective CO_(2) reduction to C_(2)H_(5)OH and provides fundamental insight into the reaction mechanism.展开更多
Nucleate site distribution plays an essential role in nucleate boiling process. In this paper1 it is pointed out that the size and spatial distribution density of nucleate sites presented on real boiling surface can b...Nucleate site distribution plays an essential role in nucleate boiling process. In this paper1 it is pointed out that the size and spatial distribution density of nucleate sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution function. It is further suggested that the surface micro geometry characteristics such as the shape of cavities should be described and analyzed qualitatively by using fractal theory.展开更多
It is very appealing that 5-hydroxymethylfurfural(HMF)is electrocatalytical oxidized as 2,5-furandicarboxylic acid(FDCA)linking to non-classical cathodic hydrogen(H_(2))production.However,the electrocatalysts for elec...It is very appealing that 5-hydroxymethylfurfural(HMF)is electrocatalytical oxidized as 2,5-furandicarboxylic acid(FDCA)linking to non-classical cathodic hydrogen(H_(2))production.However,the electrocatalysts for electrocatalytic HMF oxidative reaction(e-HMFOR)have been facing low Faradaic efficiency(FE)and high water splitting voltage.Herein,we propose a strategy of the NiSeO_(3)@(CoSeO_(3))_(4)heterojunction by constructing a Co-Ni paired site,where the Co site is in charge of adsorbing for HMF while the electrons are transferred to the Ni site,thus giving the NiSeO_(3)@(CoSeO_(3))_(4)heterojunction superior electrocata lytic performances for e-HMFOR and water splitting.By optimizing conditions,the NiSeO_(3)@(CoSeO_(3))_(4)heterojunction has high conversion of 99.7%,high selectivity of 99.9%,and high FE of 98.4%at 1.3 V,as well as low cell voltage of 1.31 V at 10 mA cm^(-2)in 1 M KOH+0.1 M HMF.This study offers a potential insight for e-HMFOR to high value-added FDCA coupling water splitting to produce H_(2)in an economical manner.展开更多
基金the financial support from the National Natural Science Foundation of China(52172110,52472231,52311530113)Shanghai"Science and Technology Innovation Action Plan"intergovernmental international science and technology cooperation project(23520710600)+1 种基金Science and Technology Commission of Shanghai Municipality(22DZ1205600)the Central Guidance on Science and Technology Development Fund of Zhejiang Province(2024ZY01011)。
文摘Investigating structural and hydroxyl group effects in electrooxidation of alcohols to value-added products by solid-acid electrocatalysts is essential for upgrading biomass alcohols.Herein,we report efficient electrocatalytic oxidations of saturated alcohols(C_(1)-C_(6))to selectively form formate using Ni Co hydroxide(Ni Co-OH)derived Ni Co_(2)O_(4)solid-acid electrocatalysts with balanced Lewis acid(LASs)and Brønsted acid sites(BASs).Thermal treatment transforms BASs-rich(89.6%)Ni Co-OH into Ni Co_(2)O_(4)with nearly equal distribution of LASs(53.1%)and BASs(46.9%)which synergistically promote adsorption and activation of OH-and alcohol molecules for enhanced oxidation activity.In contrast,BASs-enriched Ni Co-OH facilitates formation of higher valence metal sites,beneficial for water oxidation.The combined experimental studies and theoretical calculation imply the oxidation ability of C1-C6alcohols increases as increased number of hydroxyl groups and decreased HOMO-LUMO gaps:methanol(C_(1))<ethylene glycol(C_(2))<glycerol(C3)<meso-erythritol(C4)<xylitol(C5)<sorbitol(C6),while the formate selectivity shows the opposite trend from 100 to 80%.This study unveils synergistic roles of LASs and BASs,as well as hydroxyl group effect in electro-upgrading of alcohols using solid-acid electrocatalysts.
基金Natural Science Foundation of Hebei Province under Grant No.E2025201025,the Science Research Project of Hebei Education Department under Grant No.BJK2024121the Open Fund of Hebei Cangzhou Groundwater and Land Subsidence National Observation and Research Station under Grant No.CGLOS-2025-04+1 种基金the HBU Innovation Team for Multi-Disaster Prevention in Transportation Geotechnics under Grant No.IT2023C04the Research Fund for Talented Scholars of HBU under Grant No.521100221063。
文摘Tire-derived aggregate(TDA)is an engineered construction material produced from recycled scrap tires and is often used as a compressible layer overlying buried structures to reduce overburden loads.The potential amplification of ground motion in a tunnel site is well understood,but the effect of the tunnel-TDA layer system on ground surface acceleration remains unclear.In this study,both linear and nonlinear dynamic analyses were performed to evaluate the contributions of a TDA layer to the acceleration amplification at the ground surface.The numerical model was calibrated using recorded data from a shaking table test and validated against the literature results,followed by extensive parametric studies.The mechanical and geometrical parameters investigated for the TDA layer included damping ratio,density,Young’s modulus,width,thickness,and depth.The predominant frequency and intensity level of input motions were also investigated.This study showed that the presence of the TDA layer provided an additional acceleration amplification effect.The amplification was more pronounced in areas above the tunnel,particularly for the wider and shallower TDA layer subjected to high frequency and low intensity input motions.
基金supported by the National Key Research and Development Program of China(2022YFF1000102)Xi’an Agricultural Technology Research General Project(24NYGG0025)the National Natural Science Foundation of China(31702098)。
文摘Background Goat milk is increasingly recognized for high digestibility and a distinctive compositional profile.Protein acetylation,an important post-translational modification,regulates biosynthetic and metabolic pathways.This study aimed to identify critical acetylated proteins and specific modification sites involved in milk production and component synthesis in dairy goats,thereby elucidating the molecular mechanisms of lactation.We performed a comparative TMT-based acetylomic and proteomic analysis of mammary tissues from Saanen dairy goats during peak lactation and the dry period using LC–MS/MS.A candidate acetylation site was further investigated in goat mammary epithelial cells(GMECs)through site-directed mutagenesis and lipid metabolic assays,establishing functional links between acetylation and mammary lipid metabolism and providing a foundation for molecular strategies to improve milk quality and yield.Results We established a comprehensive mammary acetylome,identifying 862 significantly acetylated proteins and 2,028 modification sites across the two physiological phases.Differentially acetylated proteins were predominantly localized to the cytoplasm(39.98%).From these,54 key acetylated proteins,including MTOR,BCAT2,QARS1,GOT1,GOT2,BDH1,ACSS1,STAT5B,FABP5,and GPAM were prioritized as candidates involved in milk protein synthesis,milk fat synthesis,lactose synthesis,and other lactation-related processes.Among them,β-hydroxybutyrate dehydrogenase 1(BDH1)acetylation was characterized in detail.Members of the HDAC family were identified as primary regulators mediating BDH1 deacetylation.BDH1 acetylation promoted lipid droplet formation and triglyceride synthesis in GMECs.At the transcriptional level,BDH1 acetylation upregulated LXRα,ACSL1 and SCD1,whereas deacetylation downregulated SCD1,FASN,and ACSL1.Notably,BDH1 acetylation/deacetylation significantly reduced SREBP1 expression,linking this modification to coordinated control of lipogenic gene networks.Conclusions This study established,for the first time,the comprehensive acetylome of mammary gland tissues in dairy goats,revealing a substantial number of differentially acetylated proteins and modification sites.We demonstrate that acetylation of BDH1 regulated by HDACs promotes lipid droplet biogenesis and triglyceride synthesis in GMECs through transcriptional modulation of key lipogenic genes and suppression of SREBP1.These findings provide mechanistic insights into the post-translational regulation of mammary lipid metabolism and offer molecular targets for future genetic and nutritional strategies aimed at enhancing milk quality and yield in dairy goats.
基金supported by the National Natural Science Foundation of China(No.22208374)the Excellent Youth Scientist Award Foundation of Shandong Province(No.ZR2024YQ009)+2 种基金the Distinguished Young Scholars of the National Natural Science Foundation of China(No.22322814)CNPC Innovation Found(2022DQ02-0607)the Fundamental Research Funds for the Central Universities(No.24CX07006A).
文摘Methanol steam reforming(MSR)represents a promising route for hydrogen production,leveraging the high energy density and liquid-phase storage advantages of methanol.Copper-based catalysts have become indispensable for MSR due to their cost-effectiveness,exceptional catalytic activity,and tunable selectivity.However,persistent challenges such as thermal sintering,undesirable CO byproduct formation,diminished low-temperature reactivity,and long-term catalyst deactivation limit their broad industrial deployment.This review comprehensively examines the mechanistic pathways of MSR over Cu-based catalysts,with particular focus on differentiating catalyst formulations optimized for high-temperature(>200°C)versus low-temperature(<200°C)operation.It highlights the decisive influence of Cu nanoparticle size,electronic structure,and crystal structure on catalytic performance.Cutting-edge design strategies,including multi-element engineering,innovative synthesis techniques,and deactivation mitigation,are critically evaluated to elucidate mechanistic connections between atomic-scale structure and catalytic performance enhancement.Finally,industrial applications of commercial Cu/ZnO/Al_(2)O_(3)variants and their scalability challenges are discussed,alongside prospective strategies for catalyst innovation and engineering to advance next-generation hydrogen production.
基金supported by the National Science Foundation of China(Nos.42177042,and 42477051)the National Key R&D Program of China(No.2023YFC3708700)the Science Foundation of China University of Petroleum-Beijing(No.2462022QNXZ006).
文摘Petroleum leakage is a major groundwater contamination source,with chemical composition of water soluble fractions(WSFs)from diverse oil sources significantly impacting groundwater quality and source identification.The aim of this study was to assess impact of 15 diverse oils on groundwater quality and environmental forensics based on oil-water equilibrium experiments.Our results indicate that contamination of groundwater by gasoline and naphtha is primarily attributed to volatile hydrocarbons,while pollution from diesel,kerosene,and crude oil is predominantly from non-hydrocarbons.Rapid determination of the extent of non-hydrocarbon pollution in WSFs was achieved through a new quantitative index.Gasoline and naphtha exhibited the highest groundwater contamination potential while kerosene and light crude oils were also likely to cause groundwater contamina-tion.Although volatile hydrocarbons in the WSFs of diesel and jet fuel do not easily exceed current regulatory standards,unregulated non-hydrocarbons may pose a more severe contamination risk to groundwater.Notably,the presence of significant benzene and toluene,hydrogenation and alkylation products(e.g.,C4-C5 alkylben-zenes,alkylindenes,alkyltetralins,and dihydro-indenes),cycloalkanes in WSFs can effectively be utilized for preliminary source identification of light distillates,middle distillates,and crude oils,respectively.
基金financially supported by the National Natural Science Foundation of China(U22A20421)the Qinglan Project of Jiangsu Province,the 533 Talent Program of Huaian City,and the College Students’Innovative Entrepreneurial Training Plan Program of Jiangsu Province(X202510323027).
文摘Endogenous hydrogen systems,consisting of metal–organic coordination catalysts and alcohols,have been widely applied for the transfer hydrogenation(TH)of biomass-derived carbonyl compounds in recent years.Metal-organic coordination catalysts showed satisfactory ability of TH in the secondary alcohols,but most of them could not effectively employ the cheaper primary alcohols as hydrogen donors.Furthermore,they commonly contained high metal contents,which also led to low catalytic efficiency in significant measure.In this work,we constructed a novel magnesium single-atom catalyst(Mg-NC)with merely 0.37 wt%Mg by means of a combined self-assembly and pyrolysis strategy.The characterization results indicated that Mg was atomically dispersed and it was coordinated with four pyridinic-N in Mg-NC.Due to the obvious electron transfer from Mg to its coordinated pyridinic-N,Mg–N_(4)active centers displayed high Lewis acid-base strength with abundant content,which brought remarkable catalytic activity.When Mg-NC was used for the TH of 5-hydroxymethylfurfural(HMF)in ethanol(EtOH),2,5-bis(hydroxymethyl)furan(BHMF)yield was up to 96.3%with high productivity of 19.85 molBHMF mol_(Mg)^(−1)h^(−1)at 150°C for 5 h.More interestingly,the process of TH over Mg-NC in EtOH was proved to proceed via the hydrogen radical mechanism.Additionally,Mg-NC exhibited powerful catalytic universality;it could not only utilize other primary alcohols(such as n-propanol and n-butanol)as hydrogen donors,but also catalyze the TH of other carbonyl compounds(such as furfural,5-methylfurfural,benzaldehyde,cyclohexanone,and levulinic acid).Overall,this work offered some important clues and references to reinforce the hydrogen-supplying ability of primary alcohols in the TH of various biomass-derived carbonyl compounds to high-value fine chemicals.
文摘If you're tired of megacities that feel like nothing but glass,steel,and constant rush,Guangzhou moves at its own pace.Here,a 19th-century ancestral hall stands next to a 600-meter tower,and the day begins with tea and delicate steamed treats instead of coffee.
基金supported by the National Research Foundation of Korea(NRF)grant,funded by the Korean government(MIST),Jae-Hoon Kim(NRF-2020R1A2C2004782)Hanbyoul Cho(NRF-RS-2025-00522191)of Funderssupported by the Bio&Medical Technology Development Program of the National Research Foundation(NRF),funded by the Korean Government(MSIT),Jae-Hoon Kim of Funder(NRF-2017M3A9B 8069610).
文摘Objectives:Phosphodiesterase 1A(PDE1A)regulates intracellular cyclic nucleotide signaling and has been implicated in tumor progression,but its clinical relevance and functional role in epithelial ovarian cancer(EOC),particularly in relation to the response to platinum remain unclear.This study aimed to evaluate the clinical significance of PDE1A in EOG and to clarify its functional role in tumor progression and response to platinum-based chemotherapy.Methods:PDE1A mRNA and protein levels were analyzed using public databases,RNA sequencing,and immunohistochemistry.Correlations between PDE1A expression,clinicopathological features,and prognosis were assessed.Functional roles were investigated in ovarian cancer cell lines.Results:PDE1A was significantly overexpressed in EOC tissues compared with that in normal ovarian epithelial tissues.Overexpression correlated with advanced International Federation of Gynecology and Obstetrics(FIGO)stage,poor tumor grade,and reduced response to platinum-based chemotherapy.High PDE1A levels were linked to worse disease-free survival and overall survival,and multivariate analysis confirmed PDE1A as an independent prognostic factor.To elucidate its functional role,we performed in vitro experiments showing that PDE1A knockdown suppressed cell proliferation and colony formation,induced G1 arrest,and downregulatedβ-catenin signaling with reduced cyclin D1 and c-Myc expression.Notably,these inhibitory effects were partially rescued by lithium chloride(LiCl),a Wingless-related integration site(Wnt)/β-catenin activator.Conclusions:In conclusion,our findings identify PDE1A as a Wnt/β-catenin-linked biomarker of tumor progression and platinum resistance in EOC and provide a biological rationale for further investigation of PDE1A-targeted strategies in preclinical models.
基金financially supported by the Research and Development Program of China (2022YFA1505700)the National Natural Science Foundation of China (22475214, 22205232, 52102216)+6 种基金the Natural Science Foundation of Fujian Province (2023J06044,2022J01625, 2022-S-002)the Talent Plan of Shanghai BranchChinese Academy of Sciences (CASSHB-QNPD-2023-020)the Selfdeployment Project Research Program of Haixi Institutes,Chinese Academy of Sciences (CXZX-2022-JQ06 and CXZX-2022-GH03)the Anhui Key Laboratory of Nanomaterials and Nanotechnology,the Major Science and Technology Projects in Anhui Province(202305a12020006)the Open Project of State Key Laboratory of Inorganic Synthesis and Preparative Chemistry (2025-22)the Innovation Training Program for College Students(2025019300A, 20250193008)
文摘Co-free Li-rich Li_(1.2)Ni_(0.2)Mn_(0.6)O_(2)(LR)cathode shows the highest working capacity that can be applied to high-energy density Li-ion batteries(LIBs).However,poor cycle stability and voltage decay caused by phase transition are always hindering its further development.Herein,a novel medium-entropy Li-rich Mn-based cathode material(LRMEF)was synthesized via a simple sol-gel method.The introduction of multivalent ions(Al^(3+)/Cu^(2+)doping at Mn sites and F−doping at O sites)effectively mitigates the Jahn-Teller distortion of Mn ions and suppresses oxygen release.High-angle annular dark-field scanning transmission electron microscopy(HAADF-STEM)images confirm that this synergistic doping strategy induces the in-situ formation of an approximately 3 nm-thick spinel surface layer,which significantly enhances structural stability and ion diffusion kinetics.Besides,a series of in-situ/ex-situ characterization methods and density functional theory(DFT)calculations have been carried out to fundamentally shed light on the optimized structure-activity relationship and reaction mechanism.As a result,the LR material with entropy regulation and anion doping exhibits excellent cycling stability(189.2 mAh g^(−1)at 1 C with 84%capacity retention after 300 cycles),rate performance(164.1 mAh g^(−1)at 5 C),and voltage retention(82.7%at 1 C after 300 cycles),demonstrating great application prospects in future high-energy-density LIBs.
基金supported by the National Natural Science Foundation of China(No.51878292).
文摘Large-scale CO_(2)emissions have exacerbated the greenhouse effect,reinforcing the critical need for efficient CO_(2)mitigation methods.Plasma-catalytic technology enables CO_(2)conversion under mild conditions,especially for CO_(2)methanation(the Sabatier reaction),which has attracted significant attention due to its economic benefits and the potential for safe energy transportation via existing natural gas pipelines.The development of high-performance CO_(2)methanation catalysts remains an ongoing and long-term objective,and there is a lack of adequate in-situ characterization techniques to investigate the mechanisms.This study focuses on the Ni/La_(2)O_(3)(LN)catalyst and introduces two CO_(2)activation strategies through F and Na modifications:the Ni-Ov-Ni site activation with electron transfer from Ni0 under low-power conditions and basic site activation under high-power conditions.The LN-NaF catalysts enhance CO_(2)methanation activity across the entire power range compared to LN,achieving a CO_(2)conversion of 86.3%and CH4 selectivity of 99.4%.Additionally,LN-F(h)reaches a CH4 yield 4.15 times higher than that of LN at low power.Furthermore,in-situ diffuse reflectance infrared Fourier transform(DRIFT)spectroscopy with a self-made reactor are performed under plasma-catalytic conditions to reveal the CO_(2)adsorption and conversion mechanisms,indicating that different dopants(F,Na,and NaF)exhibit promoting effects on different intermediates,resulting in variations in CO_(2)methanation activity.This study provides valuable insights for improving catalyst performance and a thorough comprehension of mechanisms in CO_(2)methanation.
文摘Shorebirds migrate long-distances along the East Asian-Australasian Flyway(EAAF),exhibiting distinct spatiotemporal fluctuations in population dynamics.Because of habitat degradation and population declines at key stopover sites along the EAAF,the South Korea's coastal wetlands have gained increasing attention for their ecological value.This study analyzed the shorebird population dynamics across 35 coastal wetlands in South Korea from 2016 to 2024 using data from the National Marine Ecosystem Monitoring Program.For the timeseries analysis,we employed three indicators:seasonal chan ges in abundance,short-term fluctuations(Fi),and long-term trends,assessed using the TRends and Indices for Monitoring data(TRIM)model.Abundance,species richness,and Shannon diversity indices were assessed across the regions during spring and autumn.The TRIM results revealed significant population increases in both seasons("Strong increase"in spring and"Moderate increase"in autumn).Species-level trends indicated notable increases in large-bodied shorebirds,including globally threatened species such as the Far Eastern Curlew(Numenius madagascariensis).Eurasian Curlew(N.arquata),and Eurasian Oystercatcher(Haematopus ostralegus),whereas other species showed variable responses.The Yellow Sea region(Gyeonggi,Chungcheong,and Western Jeolla)showed high biodiversity indices in spring,which may be associated with time-minimization strategies,whereas autumn patterns were characterized by more flexible and selective stopover use,possibly related to energy-minimization strategies.The East Coast and Jeju regions showed the lowest biodiversity indices.Furthermore,community-level analyses using Non-metric Multidimensional Scaling(NMDS)and PERMANOVA revealed distinct clustering of bird assemblages by macro-region and season,confirming significant spatial differentiation in community composition.These findings contrast with the broader declining trends reported across the EAAF and suggest that South Korea's coastal wetlands may serve as stable alternative stopover habitats,potentially supporting the redistribution or recovery of some species.This study highlights the importance of transboundary cooperation and region-specific habitat management that reflects local ecological contexts for effective conservation.
基金financially supported by the National Natural Science Foundation of China(Nos.52473139 and U21A2098)。
文摘Hospital wastewater contains complex pollutants,including residual organic dyes and antibiotic-resistant pathogens,posing severe risks to ecosystems and human health.Conventional adsorbents,constrained by monopolar functional groups and limited surface sites,fail to remove both pollutants simultaneously.Here,we report an intelligent responsive polyurethane microsphere adsorbent doped with diallyl dimethylammonium chloride modified carbon nanotubes,termed as PUCD microspheres.The PUCD integrates bipolar adsorption sites,tunable micrometer-scale pores,and a near-infrared(NIR)-triggered in situ capture mechanism within a single platform,which achieves up to 98.3%dye removal,maintains strong adsorption performance across a wide pH range and retains 83.3%efficiency for rhodamine B after five cycles.Notably,the PUCD employs a temperature-responsive phase transition:under NIR irradiation,the microspheres undergo shrinkage,reducing the pore size to generate a‘polymer trap',enabling in situ capture of bacteria with>99%efficiencies for both Staphylococcus aureus and Escherichia coli.By immobilizing live bacteria,the PUCD microspheres substantially reduces the risk of pathogen desorption and toxin release.This promising platform offers a safe,efficient,and single-stage strategy for hospital wastewater purification,enabling the simultaneous elimination of dyes and pathogenic bacteria.
文摘At 11:00 p.m. on January 13, 2026, floodlights illuminated the launch pad at the Hainan Commercial Space Launch Site in Wenchang,south China’s Hainan Province. A Long March-8A (CZ-8A) carrier rocket lifted off with a steady roar, its exhaust lighting up the night sky as it delivered a satellite into its designated orbit.The development of China’s first commercial space launch site has been striking. Since its inaugural launch in2024, it has completed 11 missions in less than 14 months—each a success.
文摘The return capsule of the Shenzhou-20 spaceship,carrying no astronauts,touched down at the Dongfeng landing site in north China’s Inner Mongolia Autonomous Region at 9:34 a.m.(Beijing Time)on January 19,according to the China Manned Space Agency(CMSA).
基金supported by the Key Technologies Research and Development Program(2024YFC2909605)Black Soil Project of Shenyang Science and Technology Program(24-216-2-07)Fundamental Research Funds for the Central Universities(NO.N25BSS006).
文摘The pervasive accumulation of plastic waste exacerbates environmental degradation and undermines resource circularity.Selective thermal catalysis emerges as a transformative pathway for valorizing waste plastics into value-added chemicals,yet persistent challenges in catalytic activity and product selectivity demand systematic resolution.This review decodes cutting-edge advances in thermal depolymerization by converging two critical dimensions:atomic-scale active site engineering-where rational design of coordination features and interfacial architectures regulates C-C cleavage energetics and intermediate adsorption-and macromolecular-scale manipulation of polymer transient states-leveraging nanoconfinement effects,chain folding dynamics,and thermal fragmentation to accelerate conversion kinetics.We further highlight breakthroughs in operando char-acterization techniques that resolve time-evolving reaction coordinates across catalytic systems.By establishing multiscale structure-activity relationships linking catalyst configurations to polymer dynamics,this analysis derives design paradigms for next-generation upcycling systems.These principles enable economically viable,industrially scalable plastic valorization while charting a strategic trajectory toward carbon-circular economies.
基金financial supports of the National Natural Science Foundation of China (NSFC,Nos.52394202,52476056,and 52301232)the Natural Science Foundation of Chongqing Province (No.2024NSCQ-MSX1109)。
文摘Developing advanced electrocatalysts to convert CO_(2) into liquid fuels such as C_(2)H_(5)OH is critical for utilizing intermittent renewable energy.The formation of C_(2)H_(5)OH,however,is generally less favored compared with the other hydrocarbon products from Cu-based electrocatalysts.In this work,an alkanethiolmodified Cu_(2)O nanowire array(OTT-Cu_(2)O) was constructed with asymmetric Cu sites consisting of paired Cu-O and Cu-S motifs to overcome previous limitations of C_(2)H_(5)OH electrosynthesis via CO_(2)RR pathway.This catalyst achieves a high Faradaic efficiency of 45 % for CO_(2)-to-C_(2)H_(5)OH conversion at 300 m A/cm^(2),representing a more than two-fold enhancement over the Cu_(2)O electrode.Mechanistic investigations reveal that the Cu-S site exhibits distinct C-binding capability that stabilizes key intermediates(^(*)OCH_(2) and ^(*)CO),in contrast to the O-affinitive Cu-O site.The asymmetric S-Cu-O configuration promotes thermodynamically favorable asymmetric C-C coupling between ^(*)CO and ^(*)OCH_(2),forming the critical CO-OCH_(2) intermediate and facilitating C_(2)H_(5)OH production,as opposed to symmetric O-Cu-O sites that mainly generate HCOOH.This work offers an effective strategy for designing multi-active-site catalysts toward highly selective CO_(2) reduction to C_(2)H_(5)OH and provides fundamental insight into the reaction mechanism.
文摘Nucleate site distribution plays an essential role in nucleate boiling process. In this paper1 it is pointed out that the size and spatial distribution density of nucleate sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution function. It is further suggested that the surface micro geometry characteristics such as the shape of cavities should be described and analyzed qualitatively by using fractal theory.
基金supported by the National Natural Science Foundation of China(22302019)the Changzhou Sci&Tech Program(CJ20220214).
文摘It is very appealing that 5-hydroxymethylfurfural(HMF)is electrocatalytical oxidized as 2,5-furandicarboxylic acid(FDCA)linking to non-classical cathodic hydrogen(H_(2))production.However,the electrocatalysts for electrocatalytic HMF oxidative reaction(e-HMFOR)have been facing low Faradaic efficiency(FE)and high water splitting voltage.Herein,we propose a strategy of the NiSeO_(3)@(CoSeO_(3))_(4)heterojunction by constructing a Co-Ni paired site,where the Co site is in charge of adsorbing for HMF while the electrons are transferred to the Ni site,thus giving the NiSeO_(3)@(CoSeO_(3))_(4)heterojunction superior electrocata lytic performances for e-HMFOR and water splitting.By optimizing conditions,the NiSeO_(3)@(CoSeO_(3))_(4)heterojunction has high conversion of 99.7%,high selectivity of 99.9%,and high FE of 98.4%at 1.3 V,as well as low cell voltage of 1.31 V at 10 mA cm^(-2)in 1 M KOH+0.1 M HMF.This study offers a potential insight for e-HMFOR to high value-added FDCA coupling water splitting to produce H_(2)in an economical manner.
