Objective:To analyze the efficacy of whole-course local simultaneous integrated boost intensity-modulated radiotherapy(SIB-IMRT)on patients with locally advanced esophageal squamous cell carcinoma(ESCC).Methods:88 pat...Objective:To analyze the efficacy of whole-course local simultaneous integrated boost intensity-modulated radiotherapy(SIB-IMRT)on patients with locally advanced esophageal squamous cell carcinoma(ESCC).Methods:88 patients with ESCC admitted to the hospital between October 2022 and October 2024 were selected and randomly divided into two groups using a random number table.The experimental group received SIB-IMRT treatment,while the control group received conventional intensity-modulated radiotherapy(C-IMRT).The objective remission rate,immune function,tumor markers,and adverse reaction rate were compared between the two groups.Results:The objective remission rate in the experimental group was higher than that in the control group(P<0.05).Before treatment,there was no difference in immune function levels and tumor marker levels between the two groups(P>0.05).After treatment,the immune function levels in the experimental group were better than those in the control group,and the tumor marker levels were lower than those in the control group(P<0.05).The adverse reaction rate in the experimental group was lower than that in the control group(P<0.05).Conclusion:SIB-IMRT can improve the objective remission rate of patients with ESCC,protect their immune function,down-regulate tumor marker levels,and prevent side effects after treatment.展开更多
Intractable functional constipation is a type of constipation which is difficult to cure,which is usually characterized by persistent constipation,dependence on laxative and/or ineffective treatment of laxative.In rec...Intractable functional constipation is a type of constipation which is difficult to cure,which is usually characterized by persistent constipation,dependence on laxative and/or ineffective treatment of laxative.In recent years,with the change of diet structure,accelerated pace of life and the influence of socio-psychological factors,the incidence rate has increased year by year,seriously affecting the quality of life of patients.Professor Yao Shukun has remarkable clinical effect and experience in the treatment of intractable functional constipation.Professor Yao believes that,combined with the changes of people's diet structure,life style and physique,the main TCM syndrome type of clinical stubborn functional constipation is dampness-heat and blood stasis,and the main treatment should be clearing heat and resolving dampness,regulating qi and removing blood stasis;and we should pay attention to the application of the idea of"Simultaneous Treatment of Medicine and Food"in the process of diagnosis and treatment,and educate patients to change their diet structure in order to fundamentally dispel the etiology.展开更多
Upscaling of primary geological models with huge cells, especially in porous media, is the first step in fluid flow simulation. Numerical methods are often used to solve the models. The upscaling method must preserve ...Upscaling of primary geological models with huge cells, especially in porous media, is the first step in fluid flow simulation. Numerical methods are often used to solve the models. The upscaling method must preserve the important properties of the spatial distribution of the reservoir properties. An grid upscaling method based on adaptive bandwidth in kernel function is proposed according to the spatial distribution of property. This type of upscaling reduces the number of cells, while preserves the main heterogeneity features of the original fine model. The key point of the paper is upscaling two reservoir properties simultaneously. For each reservoir feature, the amount of bandwidth or optimal threshold is calculated and the results of the upscaling are obtained. Then two approaches are used to upscaling two properties simultaneously based on maximum bandwidth and minimum bandwidth. In fact, we now have a finalized upscaled model for both reservoir properties for each approach in which not only the number of their cells, but also the locations of the cells are equal. The upscaling error of the minimum bandwidth approach is less than that of the maximum bandwidth approach.展开更多
Let ξn-1<ξn-2 <ξn-2 <… < ξ1 be the zeros of the the (n -1)-th Legendre polynomial Pn-1(x) and - 1 = xn < xn-1 <… < x1 = 1 the zeros of the polynomial W n(x) =- n(n - 1) Pn-1(t)dt = (1 -x2)P&...Let ξn-1<ξn-2 <ξn-2 <… < ξ1 be the zeros of the the (n -1)-th Legendre polynomial Pn-1(x) and - 1 = xn < xn-1 <… < x1 = 1 the zeros of the polynomial W n(x) =- n(n - 1) Pn-1(t)dt = (1 -x2)P'n-1(x). By the theory of the inverse Pal-Type interpolation, for a function f(x) ∈ C[-1 1], there exists a unique polynomial Rn(x) of degree 2n - 2 (if n is even) satisfying conditions Rn(f,ξk) = f(∈ek)(1≤ k≤ n - 1) ;R'n(f,xk) = f'(xk)(1≤ k≤ n). This paper discusses the simultaneous approximation to a differentiable function f by inverse Pal-Type interpolation polynomial {Rn(f,x)} (n is even) and the main result of this paper is that if f ∈ C'[1,1], r≥2, n≥ + 2> and n is even thenholds uniformly for all x ∈ [- 1,1], where h(x) = 1 +展开更多
Background: Magnocellular deficit theory is among the different hypotheses that have been proposed to explain the pathophysiology of developmental dyslexia (DD). Dysfunction of the magnocellular system in DD has been ...Background: Magnocellular deficit theory is among the different hypotheses that have been proposed to explain the pathophysiology of developmental dyslexia (DD). Dysfunction of the magnocellular system in DD has been investigated using mainly visual evoked potentials (VEPs), particularly transient VEPs, although recently abnormal steady-state VEPs have also been reported. The brain regions responsible for the abnormal VEPs in DD have yet to be elucidated, however. In this study, we performed functional magnetic resonance imaging and electroencephalography (fMRI-EEG) simultaneously to elucidate the brain areas that were found in a previous study to be activated through stimulation of the magnocellular system, and then investigated the mechanism involved in the dysfunction seen in DD.Methods: Subjects were 20 healthy individuals (TYP group;13 men, 7 women;mean ± standard deviation age, 26.3 ± 5.53 years) and 2 men with DD (aged 42 and 30 years). Images of brain activity were acquired with 3-Tesla MRI while the viewing the reversal of low-spatial frequency and low-contrast black-and-white sinusoidal gratings. EEG was recorded concurrently to obtain steady-state VEPs.Results: Stimulus frequency-dependent VEPs were observed in the posterior region of the brain in the TYP group;however, VEP amplitudes in both DD patients were clearly smaller than those in TYP. fMRI images revealed that both the primary and secondary visual cortices were activated by black-and- white sinusoidal gratings in the TYP group, whereas activity in the visual cortex overall was reduced in both DD patients.Conclusions: Present low spatial and high reversal frequency visual stimuli activated the primary visual cortex presumably through predominant activation of the magnocellular pathway. This finding indicates that some cases of adult patients of DD involve impairment of the visual magnocellular system.展开更多
This paper investigates the simultaneous stabilization of Port-Hamiltonian(PH) systems subject to actuation saturation(AS) and input delay. Firstly, two parallel connecting PH systems subject to the AS and input delay...This paper investigates the simultaneous stabilization of Port-Hamiltonian(PH) systems subject to actuation saturation(AS) and input delay. Firstly, two parallel connecting PH systems subject to the AS and input delay are proposed. Secondly, a simultaneous stabilization control law is designed by a difference between the two feedback control laws containing the input delay.Thirdly, computing a Lyapunov-Krasovskii function assures the simultaneous stabilization of the above systems. Finally, simulation is given to show the correctness of the proposed contents.展开更多
The working mechanism of MFC used for simultaneous nitrogen removal and electricity generation was studied.The results show that the electrode biofilms and suspension had different modes of electron transfer.The micro...The working mechanism of MFC used for simultaneous nitrogen removal and electricity generation was studied.The results show that the electrode biofilms and suspension had different modes of electron transfer.The microorganisms growing on the electrodes and bioflocs could transfer electrons by direct contact and intermediaries respectively.The electrode biofilms and bioflocs were dominant in different functional spaces,and played a synergistic role in the process of contaminant removal,but showed a certain competitive relationship in the process of electricity generation.This study can provide a theoretical basis for the development of a new low-consumption wastewater treatment technology and promote technological innovation in wastewater treatment.展开更多
In this paper,the adaptive robust simultaneous stabilization problem of uncertain multiple n-degree-of-freedom(n-DOF)robot systems is studied using the Hamiltonian function method,and the corresponding adaptive L2 con...In this paper,the adaptive robust simultaneous stabilization problem of uncertain multiple n-degree-of-freedom(n-DOF)robot systems is studied using the Hamiltonian function method,and the corresponding adaptive L2 controller is designed.First,we investigate the adaptive simultaneous stabilization problem of uncertain multiple n-DOF robot systems without external disturbance.Namely,the single uncertain n-DOF robot system is transformed into an equivalent Hamiltonian form using the unified partial derivative operator(UP-DO)and potential energy shaping method,and then a high dimensional Hamiltonian system for multiple uncertain robot systems is obtained by applying augmented dimension technology,and a single output feedback controller is designed to ensure the simultaneous stabilization for the higher dimensional Hamiltonian system.On this basis,we further study the adaptive robust simultaneous stabilization control problem for the uncertain multiple n-DOF robot systems with external disturbances,and design an adaptive robust simultaneous stabilization controller.Finally,the simulation results show that the adaptive robust simultaneous stabilization controller designed in this paper is very effective in stabilizing multi-robot systems at the same time.展开更多
This paper studies simultaneous stabilization of a class of nonlinear descriptor systems via the Hamiltonian function method. Firstly, based on the Hamiltonian realization of the nonlinear descriptor systems and a sui...This paper studies simultaneous stabilization of a class of nonlinear descriptor systems via the Hamiltonian function method. Firstly, based on the Hamiltonian realization of the nonlinear descriptor systems and a suitable output feedback, two nonlinear descriptor systems are equivalently transformed into two nonlinear Hamiltonian differential-algebraic systems by a nonsingular transformation, and a sufficient condition for two closed-loop systems to be impulse-free is given. The two systems are then combined to generate an augmented dissipative Hamiltonian differential-algebraic system by using the system-augmentation technique, based on which a simultaneous stabilization controller and a robust simultaneous stabilization controller are designed for the two systems. Secondly, the case of more than two nonlinear descriptor systems is investigated, and two new results are proposed for the simultaneous stabilization and robust simultaneous stabilization, respectively. Finally, an illustrative example is studied by using the results proposed in this paper, and simulations show that the simultaneous stabilization controllers obtained in this paper work very well.展开更多
文摘Objective:To analyze the efficacy of whole-course local simultaneous integrated boost intensity-modulated radiotherapy(SIB-IMRT)on patients with locally advanced esophageal squamous cell carcinoma(ESCC).Methods:88 patients with ESCC admitted to the hospital between October 2022 and October 2024 were selected and randomly divided into two groups using a random number table.The experimental group received SIB-IMRT treatment,while the control group received conventional intensity-modulated radiotherapy(C-IMRT).The objective remission rate,immune function,tumor markers,and adverse reaction rate were compared between the two groups.Results:The objective remission rate in the experimental group was higher than that in the control group(P<0.05).Before treatment,there was no difference in immune function levels and tumor marker levels between the two groups(P>0.05).After treatment,the immune function levels in the experimental group were better than those in the control group,and the tumor marker levels were lower than those in the control group(P<0.05).The adverse reaction rate in the experimental group was lower than that in the control group(P<0.05).Conclusion:SIB-IMRT can improve the objective remission rate of patients with ESCC,protect their immune function,down-regulate tumor marker levels,and prevent side effects after treatment.
基金Evaluation and promotion of appropriate technology for the prevention and treatment of common frequently occurring diseases at grassroots level(No.2014BA108B00)。
文摘Intractable functional constipation is a type of constipation which is difficult to cure,which is usually characterized by persistent constipation,dependence on laxative and/or ineffective treatment of laxative.In recent years,with the change of diet structure,accelerated pace of life and the influence of socio-psychological factors,the incidence rate has increased year by year,seriously affecting the quality of life of patients.Professor Yao Shukun has remarkable clinical effect and experience in the treatment of intractable functional constipation.Professor Yao believes that,combined with the changes of people's diet structure,life style and physique,the main TCM syndrome type of clinical stubborn functional constipation is dampness-heat and blood stasis,and the main treatment should be clearing heat and resolving dampness,regulating qi and removing blood stasis;and we should pay attention to the application of the idea of"Simultaneous Treatment of Medicine and Food"in the process of diagnosis and treatment,and educate patients to change their diet structure in order to fundamentally dispel the etiology.
文摘Upscaling of primary geological models with huge cells, especially in porous media, is the first step in fluid flow simulation. Numerical methods are often used to solve the models. The upscaling method must preserve the important properties of the spatial distribution of the reservoir properties. An grid upscaling method based on adaptive bandwidth in kernel function is proposed according to the spatial distribution of property. This type of upscaling reduces the number of cells, while preserves the main heterogeneity features of the original fine model. The key point of the paper is upscaling two reservoir properties simultaneously. For each reservoir feature, the amount of bandwidth or optimal threshold is calculated and the results of the upscaling are obtained. Then two approaches are used to upscaling two properties simultaneously based on maximum bandwidth and minimum bandwidth. In fact, we now have a finalized upscaled model for both reservoir properties for each approach in which not only the number of their cells, but also the locations of the cells are equal. The upscaling error of the minimum bandwidth approach is less than that of the maximum bandwidth approach.
文摘Let ξn-1<ξn-2 <ξn-2 <… < ξ1 be the zeros of the the (n -1)-th Legendre polynomial Pn-1(x) and - 1 = xn < xn-1 <… < x1 = 1 the zeros of the polynomial W n(x) =- n(n - 1) Pn-1(t)dt = (1 -x2)P'n-1(x). By the theory of the inverse Pal-Type interpolation, for a function f(x) ∈ C[-1 1], there exists a unique polynomial Rn(x) of degree 2n - 2 (if n is even) satisfying conditions Rn(f,ξk) = f(∈ek)(1≤ k≤ n - 1) ;R'n(f,xk) = f'(xk)(1≤ k≤ n). This paper discusses the simultaneous approximation to a differentiable function f by inverse Pal-Type interpolation polynomial {Rn(f,x)} (n is even) and the main result of this paper is that if f ∈ C'[1,1], r≥2, n≥ + 2> and n is even thenholds uniformly for all x ∈ [- 1,1], where h(x) = 1 +
文摘Background: Magnocellular deficit theory is among the different hypotheses that have been proposed to explain the pathophysiology of developmental dyslexia (DD). Dysfunction of the magnocellular system in DD has been investigated using mainly visual evoked potentials (VEPs), particularly transient VEPs, although recently abnormal steady-state VEPs have also been reported. The brain regions responsible for the abnormal VEPs in DD have yet to be elucidated, however. In this study, we performed functional magnetic resonance imaging and electroencephalography (fMRI-EEG) simultaneously to elucidate the brain areas that were found in a previous study to be activated through stimulation of the magnocellular system, and then investigated the mechanism involved in the dysfunction seen in DD.Methods: Subjects were 20 healthy individuals (TYP group;13 men, 7 women;mean ± standard deviation age, 26.3 ± 5.53 years) and 2 men with DD (aged 42 and 30 years). Images of brain activity were acquired with 3-Tesla MRI while the viewing the reversal of low-spatial frequency and low-contrast black-and-white sinusoidal gratings. EEG was recorded concurrently to obtain steady-state VEPs.Results: Stimulus frequency-dependent VEPs were observed in the posterior region of the brain in the TYP group;however, VEP amplitudes in both DD patients were clearly smaller than those in TYP. fMRI images revealed that both the primary and secondary visual cortices were activated by black-and- white sinusoidal gratings in the TYP group, whereas activity in the visual cortex overall was reduced in both DD patients.Conclusions: Present low spatial and high reversal frequency visual stimuli activated the primary visual cortex presumably through predominant activation of the magnocellular pathway. This finding indicates that some cases of adult patients of DD involve impairment of the visual magnocellular system.
基金supported by Fundamental Research Funds for the Central Universities of China(No.2682014BR009EM)。
文摘This paper investigates the simultaneous stabilization of Port-Hamiltonian(PH) systems subject to actuation saturation(AS) and input delay. Firstly, two parallel connecting PH systems subject to the AS and input delay are proposed. Secondly, a simultaneous stabilization control law is designed by a difference between the two feedback control laws containing the input delay.Thirdly, computing a Lyapunov-Krasovskii function assures the simultaneous stabilization of the above systems. Finally, simulation is given to show the correctness of the proposed contents.
基金Supported by National Natural Science Foundation of China （60774011, 60674024）, Natural Science Foundation of Zhejiang Province （Y105141）, and Natural Science Foundation of Fujian Province （2008J0026）
基金Supported by Natural Science Foundation of Shandong Province,China(ZR2019QEE039)Natural Science Foundation of Zhejiang Province,China(LY18E080007)National Natural Science Foundation of China(51808494)
文摘The working mechanism of MFC used for simultaneous nitrogen removal and electricity generation was studied.The results show that the electrode biofilms and suspension had different modes of electron transfer.The microorganisms growing on the electrodes and bioflocs could transfer electrons by direct contact and intermediaries respectively.The electrode biofilms and bioflocs were dominant in different functional spaces,and played a synergistic role in the process of contaminant removal,but showed a certain competitive relationship in the process of electricity generation.This study can provide a theoretical basis for the development of a new low-consumption wastewater treatment technology and promote technological innovation in wastewater treatment.
文摘In this paper,the adaptive robust simultaneous stabilization problem of uncertain multiple n-degree-of-freedom(n-DOF)robot systems is studied using the Hamiltonian function method,and the corresponding adaptive L2 controller is designed.First,we investigate the adaptive simultaneous stabilization problem of uncertain multiple n-DOF robot systems without external disturbance.Namely,the single uncertain n-DOF robot system is transformed into an equivalent Hamiltonian form using the unified partial derivative operator(UP-DO)and potential energy shaping method,and then a high dimensional Hamiltonian system for multiple uncertain robot systems is obtained by applying augmented dimension technology,and a single output feedback controller is designed to ensure the simultaneous stabilization for the higher dimensional Hamiltonian system.On this basis,we further study the adaptive robust simultaneous stabilization control problem for the uncertain multiple n-DOF robot systems with external disturbances,and design an adaptive robust simultaneous stabilization controller.Finally,the simulation results show that the adaptive robust simultaneous stabilization controller designed in this paper is very effective in stabilizing multi-robot systems at the same time.
基金Supported by the National Natural Science Foundation of China (Grant No. 60774009)the Natural Science Foundation of Shandong Province(Grant No. Y2006G10)the Research Fund for the Doctoral Program of Chinese Higher Education (Grant No. 200804220028)
文摘This paper studies simultaneous stabilization of a class of nonlinear descriptor systems via the Hamiltonian function method. Firstly, based on the Hamiltonian realization of the nonlinear descriptor systems and a suitable output feedback, two nonlinear descriptor systems are equivalently transformed into two nonlinear Hamiltonian differential-algebraic systems by a nonsingular transformation, and a sufficient condition for two closed-loop systems to be impulse-free is given. The two systems are then combined to generate an augmented dissipative Hamiltonian differential-algebraic system by using the system-augmentation technique, based on which a simultaneous stabilization controller and a robust simultaneous stabilization controller are designed for the two systems. Secondly, the case of more than two nonlinear descriptor systems is investigated, and two new results are proposed for the simultaneous stabilization and robust simultaneous stabilization, respectively. Finally, an illustrative example is studied by using the results proposed in this paper, and simulations show that the simultaneous stabilization controllers obtained in this paper work very well.
