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Research on system-of-systems combat simulation model formal specification and representation 被引量:3
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作者 Liu Chen 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2006年第4期901-909,共9页
To makesystem-of-systems combat simulation models easy to be developed and reused, simulation model formal specification and representation are researched. According to the view of system-of-systems combat simulation,... To makesystem-of-systems combat simulation models easy to be developed and reused, simulation model formal specification and representation are researched. According to the view of system-of-systems combat simulation, and based on DEVS, the simulation model's fundamental formalisms are explored. It includes entity model, system-of-systems model and experiment model. It also presents rigorous formal specification. XML data exchange standard is combined to design the XML based language, SCSL, to support simulation model representation. The corresponding relationship between SCSL and simulation model formalism is discussed and the syntax and semantics of elements in SCSL are detailed. Based on simulation model formal specification, the abstract simulation algorithm is given and SCSL virtual machine, which is capable of automatically interpreting and executing simulation model represented by SCSL, is designed. Finally an application case is presented, which can show the validation of the theory and verification of SCSL. 展开更多
关键词 simulation model formalism simulation model representation system-of-systems combat simulation language simulation virtual machine.
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PM_(10) dust emission in the Erenhot-Huailai zone of northern China based on model simulation
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作者 WANG Yong YAN Ping +3 位作者 WU Wei WANG Yijiao HU Chanjuan LI Shuangquan 《Journal of Arid Land》 2025年第3期324-336,共13页
The Erenhot-Huailai zone, as an important dust emission source area in northern China, affects the air quality of Beijing City, Tianjin City, and Hebei Province and human activities in this zone have a profound impact... The Erenhot-Huailai zone, as an important dust emission source area in northern China, affects the air quality of Beijing City, Tianjin City, and Hebei Province and human activities in this zone have a profound impact on surface dust emission. In order to explore the main source areas of surface dust emission and quantify the impacts of human activities on surface dust emission, we investigated the surface dust emission of different land types on the Erenhot-Huailai zone by model simulation, field observation, and comparative analysis. The results showed that the average annual inhalable atmospheric particles(PM_(10)) dust emission fluxes in arid grassland, Hunshandake Sandy Land, semi-arid grassland,semi-arid agro-pastoral area, dry sub-humid agro-pastoral area, and semi-humid agro-pastoral area were 4.41, 0.71, 3.64, 1.94, 0.24, and 0.14 t/hm^(2), respectively, and dust emission in these lands occurred mainly from April to May. Due to the influence of human activities on surface dust emission, dust emission fluxes from different land types were 1.66–4.41 times greater than those of their background areas, and dust emission fluxes from the main dust source areas were 1.66–3.89 times greater than those of their background areas. According to calculation, the amount of PM_(10) dust emission influenced by human disturbance accounted for up to 58.00% of the total dust emission in the study area. In addition, the comparative analysis of model simulation and field observation results showed that the simulated and observed dust emission fluxes were relatively close to each other, with differences ranging from 0.01 to 0.21 t/hm^(2) in different months, which indicated that the community land model version 4.5(CLM4.5) had a high accuracy. In conclusion, model simulation results have important reference significance for identifying dust source areas and quantifying the contribution of human activities to surface dust emission. 展开更多
关键词 northern China classification of land type model simulation dust emission human disturbance
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Multi-agent Based Hierarchy Simulation Models of Carrier-based Aircraft Catapult Launch 被引量:19
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作者 王维军 屈香菊 郭林亮 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2008年第3期223-231,共9页
With the aid of multi-agent based modeling approach to complex systems, the hierarchy simulation models of carrier-based aircraft catapult launch are developed. Ocean, carrier, aircraft, and atmosphere are treated as ... With the aid of multi-agent based modeling approach to complex systems, the hierarchy simulation models of carrier-based aircraft catapult launch are developed. Ocean, carrier, aircraft, and atmosphere are treated as aggregation agents, the detailed components like catapult, landing gears, and disturbances are considered as meta-agents, which belong to their aggregation agent. Thus, the model with two layers is formed i.e. the aggregation agent layer and the meta-agent layer. The information communication among all agents is described. The meta-agents within one aggregation agent communicate with each other directly by information sharing, but the meta-agents, which belong to different aggregation agents exchange their information through the aggregation layer first, and then perceive it from the sharing environment, that is the aggregation agent. Thus, not only the hierarchy model is built, but also the environment perceived by each agent is specified. Meanwhile, the problem of balancing the independency of agent and the resource consumption brought by real-time communication within multi-agent system (MAS) is resolved. Each agent involved in carrier-based aircraft catapult launch is depicted, with considering the interaction within disturbed atmospheric environment and multiple motion bodies including carrier, aircraft, and landing gears. The models of reactive agents among them are derived based on tensors, and the perceived messages and inner frameworks of each agent are characterized. Finally, some results of a simulation instance are given. The simulation and modeling of dynamic system based on multi-agent system is of benefit to express physical concepts and logical hierarchy clearly and precisely. The system model can easily draw in kinds of other agents to achieve a precise simulation of more complex system. This modeling technique makes the complex integral dynamic equations of multibodies decompose into parallel operations of single agent, and it is convenient to expand, maintain, and reuse the program codes. 展开更多
关键词 multi-agent system (MAS) multi-agent based modeling (MABM) TENSOR carrier-based aircraft catapult launch hierarchy simulation model
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Methods of Validating Simulation Model and Program Design
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作者 陈利 张庆明 +1 位作者 王晓英 汪于力 《Journal of Beijing Institute of Technology》 EI CAS 2002年第2期125-128,共4页
Validating simulation model is one of the important aspects for modeling and simulation. Some methods of validating model are compared and analyzed. Several typical methods, such as TIC’s inequality coefficient, gray... Validating simulation model is one of the important aspects for modeling and simulation. Some methods of validating model are compared and analyzed. Several typical methods, such as TIC’s inequality coefficient, gray interconnected analysis, direct spectrum estimation, maximum entropy spectral estimation based on Burg or Marple, are chosen and programmed in C language. Some examples by using the program are given. The results show that the program is available and it is best to adopt multi methods for validating models. 展开更多
关键词 VALIDATION simulation model interconnected analysis frequency spectrum estimation
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Two-Dimensional Static Numerical Modeling and Simulation of AlGaN/GaN HEMT
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作者 薛丽君 夏洋 +6 位作者 刘明 王燕 邵雪 鲁净 马杰 谢常青 余志平 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2006年第2期298-303,共6页
AIGaN/GaN HEMTs are investigated by numerical simulation from the self-consistent solution of Schr6dinger-Poisson-hydrodynamic (HD) systems. The influences of polarization charge and quantum effects are considered i... AIGaN/GaN HEMTs are investigated by numerical simulation from the self-consistent solution of Schr6dinger-Poisson-hydrodynamic (HD) systems. The influences of polarization charge and quantum effects are considered in this model. Then the two-dimensional conduction band and electron distribution, electron temperature characteristics, Id versus Vd and Id versus Vg, transfer characteristics and transconductance curves are obtained. Corresponding analysis and discussion based on the simulation results are subsequently given. 展开更多
关键词 AIGaN/GaN HEMT 2D modeling and simulation polarization charges quantum effects
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Quantifying Responses of Winter Wheat Physiological Processes to Soil Water Stress for Use in Growth Simulation Modeling 被引量:44
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作者 HUJi-Chao CAOWei-Xing +2 位作者 ZHANGJia-Bao JIANGDong FENGJie 《Pedosphere》 SCIE CAS CSCD 2004年第4期509-518,共10页
A deep understanding of crop-water eco-physiological relations is the basis for quantifying plant physiological responses to soil water stress. Pot experiments were conducted to investigate the winter wheat crop-water... A deep understanding of crop-water eco-physiological relations is the basis for quantifying plant physiological responses to soil water stress. Pot experiments were conducted to investigate the winter wheat crop-water relations under both drought and waterlogging conditions in two sequential growing seasons from 2000 to 2002, and then the data were used to develop and validate models simulating the responses of winter wheat growth to drought and waterlogging stress. The experiment consisted of four treatments, waterlogging (keep 1 to 2 cm water layer depth above soil surface), control (70%-80% field capacity), light drought (40%-50% field capacity) and severe drought (30%-40% field capacity) with six replicates at five stages in the 2000-2001 growth season. Three soil water content treatments (waterlogging, control and drought) with two replicates were designed in the 2001-2002 growth season. Waterlogging and control treatments are the same as in the 2000-2001 growth season. For the drought treatment, no water was supplied and the soil moisture decreased from field capacity to wilting point. Leaf net photosynthetic rate, transpiration rate, predawn leaf water potential, soil water potential, soil water content and dry matter weight of individual organs were measured. Based on crop-water eco-physiological relations, drought and waterlogging stress factors for winter wheat growth simulation model were put forward. Drought stress factors integrated soil water availability, the sensitivity of different development stages and the difference between physiological processes (such as photosynthesis, transpiration and partitioning). The quantification of waterlogging stress factor considered different crop species, soil water status, waterlogging days and sensitivity at different growth stages. Data sets from the pot experiments revealed favorable performance reliability for the simulation sub-models with the drought and waterlogging stress factors. 展开更多
关键词 crop simulation model DROUGHT water stress factor WATERLOGGING winterwheat
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Rice Yield Estimation by Integrating Remote Sensing with Rice Growth Simulation Model 被引量:23
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作者 O.ABOU-ISMAIL 《Pedosphere》 SCIE CAS CSCD 2004年第4期519-526,共8页
Since remote sensing can provide information on the actual status of an agricultural crop, the integration between remote sensing data and crop growth simulation models has become an important trend for yield estimati... Since remote sensing can provide information on the actual status of an agricultural crop, the integration between remote sensing data and crop growth simulation models has become an important trend for yield estimation and prediction.The main objective of this research was to combine a rice growth simulation model with remote sensing data to estimate rice grain yield for different growing seasons leading to an assessment of rice yield at regional levels. Integration between NOAA (National Oceanic and Atmospheric Administration) AVHRR (Advanced Very High Resolution Radiometer) data and the rice growth simulation model ORYZA1 to develop a new software, which was named as Rice-SRS Model, resulted in accurate estimates for rice yield in Shaoxing, China, with an estimation error reduced to 1.03% and 0.79% over-estimation and 0.79% under-estimation for early, single and late season rice, respectively. Selecting suitable dates for remote sensing images was an important factor which could influence estimation accuracy. Thus, given the different growing periods for each rice season, four images were needed for early and late rice, while five images were preferable for single season rice.Estimating rice yield using two or three images was possible, however, if images were obtained during the panicle initiation and heading stages. 展开更多
关键词 remote sensing rice growth simulation model rice yield estimation
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Plant Temperature and Its Simulation Model of Thermo-Sensitive Genic Male Sterile Rice 被引量:7
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作者 LU Chuan-gen XIA Shi-jian +2 位作者 CHEN Jing Hu Ning YAO Ke-min 《Rice science》 SCIE 2008年第3期223-231,共9页
Plant temperature (Tp) and its relations to the microclimate of rice colony and irrigation water were studied using a thermo-sensitive genic male sterile (TGMS) rice line, Pei'ai 64S. Significant differences in t... Plant temperature (Tp) and its relations to the microclimate of rice colony and irrigation water were studied using a thermo-sensitive genic male sterile (TGMS) rice line, Pei'ai 64S. Significant differences in the daily change of temperature were detected between Tp and air temperature at the height of 150 cm (TA). From 8:00 to 20:00, Tp was lower than TA, but they were similar during 21:00 to next 7:00. The maximum Tp occurred one hour earlier than the maximum TA, though they both reached the minimum at 6:00. Tp fluctuated less than TA. At the same height, during 6:00-13:00, Tp was higher than air temperature (Ta), and Tp reached the maximum one hour earlier than Ta. During the rest time on sunny day, Tp was close to or even a little lower than Ta. On overcast day, Tp was higher than Ta in the whole day, and both maximized at the same time. In addition, Tp was regulated by solar radiation, cloudage and wind speed in daytime, and by irrigation water at night. The present study indicated that a TA of 29.6℃ was the critical point, at which Tp was increased or decreased by irrigation water. Tp and the difference between water and air temperatures showed a conic relation. Tp fluctuation was also regulated by the absorption or reflection of solar radiation by leaves during daytime and release of heat energy during nighttime. By analysis on correlation and regression simulation, two models of Tp were established. 展开更多
关键词 RICE plant temperature air temperature simulation model thermo-sensitive genic male sterility
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UWB Channel Modeling and Simulation with Continuous Frequency Response 被引量:7
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作者 Kai Mao Qiuming Zhu +4 位作者 Xijuan Ye Ruirui Feng Fuqiao Duan Yang Miao Maozhong Song 《China Communications》 SCIE CSCD 2022年第11期88-98,共11页
Ultra-wideband(UWB)technology is a prospective technology for high-rate transmission and accurate localization in the future communication systems.State-of-art channel modeling approaches usually divide the UWB channe... Ultra-wideband(UWB)technology is a prospective technology for high-rate transmission and accurate localization in the future communication systems.State-of-art channel modeling approaches usually divide the UWB channel into several sub-band channels and model them independently.By considering frequency-dependent channel parameters,a novel analytical UWB channel model with continuous frequency response is proposed.The composite effect of all frequency components within the UWB channel on the channel impulse response(CIR)of delay domain is derived based on the continuous channel transfer function(CTF)of frequency domain.On this basis,a closed-form simulation model for UWB channels and geometry-based parameter calculation method are developed,which can guarantee the continuity of channel characteristics on the frequency domain and greatly reduce the simulation complexity.Finally,the proposed method is applied to generate UWB channel with 2 GHz bandwidth at sub-6GHz and millimeter wave(mmWave)bands,respectively.The channel measurements are also carried out to validate the proposed method.The simulated CIR and power gain are shown to be in good agreement with the measurement data.Moreover,the comparison results of power gain and Doppler power spectral density(DPSD)show that the proposed UWB channel model Received:Apr.23,2022 Revised:Jun.09,2022 Editor:Wei Fan achieves a good balance between the simulation accuracy and efficiency. 展开更多
关键词 ultra-wideband(UWB)channel continuous frequency response frequency-dependent channel parameters simulation model channel measurement
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Feasibility and simulation model of a pilot scale membrane bioreactor for wastewater treatment and reuse from Chinese traditional medicine 被引量:5
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作者 REN Nan-qi YAN Xian-feng +3 位作者 CHEN Zhao-bo HU Dong-xue GONG Man-li GUO Wan-qian 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2007年第2期129-134,共6页
The lack and pollution of water resource make wastewater reuse necessary. The pilot scale long-term tests for submerged membrane bioreactor were conducted to treat the effluents of anaerobic or aerobic treatment proce... The lack and pollution of water resource make wastewater reuse necessary. The pilot scale long-term tests for submerged membrane bioreactor were conducted to treat the effluents of anaerobic or aerobic treatment process for the high-strength Chinese traditional medicine wastewater. This article was focused on the feasibility of the wastewater treatment and reuse at shorter hydraulic retention time (HRT) of 5.0, 3.2 and 2.13 h. MLSS growth, membrane flux, vacuum values and chemical cleaning periods were also investigated. The experimental results of treating two-phase anaerobic treatment effluent demonstrated that the CODfilt was less than 100 mg/L when the influent COD was between 500-10000 mg/L at HRT of 5.0 h, which could satisfy the normal discharged standard in China. The experimental results to treat cross flow aerobic reactor effluent demonstrated that the average value of CODfilt was 17.28 mg/L when the average value of influent COD was 192.84 mg/L at HRT of 2.13 h during 106 d, which could completely meet the normal standard for water reuse. The maximum MLSS and MLVSS reached 24000 and 14500 mg/L at HRT of 3.2 h respectively. Membrane flux had maximal resume degrees of 94.7% at vacuum value of 0.02 MPa after cleaning. Chemical cleaning periods of membrane module were 150 d. A simulation model of operational parameters was also established based on the theory of back propagation neural network and linear regression of traditional mathematical model. The simulation model showed that the optimum operational parameters were suggested as follows: HRT was 5.0 h, SRT was 100 d, the range of COD loading rate was between 10.664-20.451 kg/(m3.d), the range of MLSS was between 7543-13694 mg/L. 展开更多
关键词 submerged membrane bioreactor (SMBR) Chinese traditional medicine wastewater hydraulic retention time (HRT) simulation model pilot scale test
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A New Method with High Confidence for Validation of Computer Simulation Models of Flight Systems 被引量:5
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作者 Zhou XianminShanghai Research & Development Centre, 412 Guil in Road, Shanghai 200233, P.R.China 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 1993年第4期43-52,共10页
Computer simulation models may by used to gain further information about missile performance variability. Model validation is an important aspect of the test program for a missile system. Validation provides a basis f... Computer simulation models may by used to gain further information about missile performance variability. Model validation is an important aspect of the test program for a missile system. Validation provides a basis for confidence in the model's results and is a necessary step if the model is to be used to draw inference about the behavior of the real missile. This paper is a review of methods useful for validation of computer simulation models of missile systems and provides a new method with high degree of confidence for validation of computer simulation models of missile systems. Some examples of the use of the new method in validating computer simulation models are given. 展开更多
关键词 model validation model credibility simulation modeling System simulation.
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Rice yield estimation using remote sensing and simulation model 被引量:7
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作者 黄敬峰 唐蜀川 +1 位作者 OttsamaAbou-Ismail 王人潮 《Journal of Zhejiang University Science》 CSCD 2002年第4期461-466,共6页
Remote sensing techniques have the potential to provide information on agricultural crops quantitatively , instantaneously and above all nondestructively over large areas . Crop simulation models describe the relation... Remote sensing techniques have the potential to provide information on agricultural crops quantitatively , instantaneously and above all nondestructively over large areas . Crop simulation models describe the relationship between physiological processes in plants and environmental growing conditions. The integration between remote sensing data and crop growth simulation model is an important trend for yield estimation and prediction, since remote sensing can provide information on the actual status of the agricultural crop. In this study, a new model(Rice-SRS) was developed based mainly on ORYZA1 model and modified to accept remote sensing data as input from different sources. The model can accept three kinds of NDVI data: NOAA AVHRR(LAC)-NDVI,NOAA AVHRR(GAC)-NDVI and radiometric measurements-NDVI. The integration between NOAA AVHRR (LAC) data and simulation model as applied to Rice-SRS resulted in accurate estimates for rice yield in the Shaoxing area, reduced the estimating error to 1.027%,0.794% and (-0.787%) for early, single, and late season respectively. Utilizing NDVI data derived from NOAA AVHRR (GAC) as input in Rice-SRS can yield good estimation for rice yield with the average error (-7.43%). Testing the new model for radiometric measurements showed that the average estimation error for 10 varieties under early rice conditions was less than 1%. 展开更多
关键词 Rice Remote sensing NOAA(National Oceanic and Atmospheric Adiministration) AVHRR(Advanced Very High Resolution Radiometer) simulation model LACC (Local Area coverage) GAC(Global Area Coverage)
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DYNAMICS MODEL AND SIMULATION OF FLAT VALVE SYSTEM OF INTERNAL COMBUSTION WATER PUMP 被引量:39
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作者 Zhang Hongxin Zhang Tiezhu +2 位作者 Wang Yushun Zhao Hong Huo Wei 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2005年第3期411-414,共4页
The dynamics differential equations are constructed, and the initial conditions are also given. Simulation shows the following conclusions: The water pressure in cylinder has great instantaneous pulsation and phase s... The dynamics differential equations are constructed, and the initial conditions are also given. Simulation shows the following conclusions: The water pressure in cylinder has great instantaneous pulsation and phase step when outlet valve or inlet valve opens, but is more gently in other time; The volume efficiency is influenced by the output pressure slightly, and decreases as the working rotational speed increases; When the inherent frequency of the valves is integer multiple of the working frequency, the volume efficiency of system will decrease evidently. 展开更多
关键词 Check valve simulation Dynamics model Internal combustion water pump(ICWP)
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Model architecture-oriented combat system effectiveness simulation based on MDE 被引量:3
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作者 Yonglin Lei Ning Zhu +2 位作者 Jian Yao Hessam Sarjoughian Weiping Wang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2017年第5期900-922,共23页
Combat system effectiveness simulation (CSES) is a special type of complex system simulation. Three non-functional requirements (NFRs), i.e. model composability, domain specific modeling, and model evolvability, are g... Combat system effectiveness simulation (CSES) is a special type of complex system simulation. Three non-functional requirements (NFRs), i.e. model composability, domain specific modeling, and model evolvability, are gaining higher priority from CSES users when evaluating different modeling methodologies for CSES. Traditional CSES modeling methodologies are either domain-neutral (lack of domain characteristics consideration and limited support for model composability) or domain-oriented (lack of openness and evolvability) and fall short of the three NFRs. Inspired by the concept of architecture in systems engineering and software engineering fields, we extend it into a concept of model architecture for complex simulation systems, and propose a model architecture-oriented modeling methodology in which the model architecture plays a central role in achieving the three NFRs. Various model-driven engineering (MDE) approaches and technologies, including simulation modeling platform (SMP), unified modeling language (UML), domain specific modeling (DSM), eclipse modeling framework (EMF), graphical modeling framework (GMF), and so forth, are applied where possible in representing the CSES model architecture and its components' behaviors from physical and cognitive domain aspects. A prototype CSES system, called weapon effectiveness simulation system (WESS), and a non-trivial air-combat simulation example are presented to demonstrate the methodology. 展开更多
关键词 combat system effectiveness simulation (CSES) model architecture model-driven engineering (MDE) simulation modeling platform (SMP) domain specific modeling (DSM) weapon effectiveness simulation system (WESS)
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Water and heat transport in hilly red soil of southern China:II. Modeling and simulation 被引量:2
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作者 吕军 黄志珍 韩晓非 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE EI CAS CSCD 2005年第5期338-345,共8页
Simulation models of heat and water transport have not been rigorously tested for the red soils of southern China. Based on the theory of nonisothermal water-heat coupled transfer, a simulation model, programmed in Vi... Simulation models of heat and water transport have not been rigorously tested for the red soils of southern China. Based on the theory of nonisothermal water-heat coupled transfer, a simulation model, programmed in Visual Basic 6.0, was developed to predict the coupled transfer of water and heat in hilly red soil. A series of soil column experiments for soil water and heat transfer, including soil columns with closed and evaporating top ends, were used to test the simulation model. Results showed that in the closed columns, the temporal and spatial distribution of moisture and heat could be very well predicted by the model, while in the evaporating columns, the simulated soil water contents were somewhat different from the observed ones. In the heat flow equation by Taylor and Lary (1964), the effect of soil water evaporation on the heat flow is not involved, which may be the main reason for the differences between simulated and observed results. The predicted temperatures were not in agreement with the observed one with thermal conductivities calculated by de Vries and Wierenga equations, so that it is suggested that Kh, soil heat conductivity, be multiplied by 8.0 for the first 6.5 h and by 1.2 later on. Sensitivity analysis of soil water and heat coefficients showed that the saturated hydraulic conductivity, KS, and the water diffusivity, D(θ), had great effects on soil water transport; the variation of soil porosity led to the difference of soil thermal properties, and accordingly changed temperature redistribution, which would affect water redistribution. 展开更多
关键词 Red soil Coupled transfer of soil water and heat simulation model VALIDATION Sensitivity analysis
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GENERALIZED SIMULATION MODEL FOR MILLED SURFACE TOPOGRAPHY-APPLICATION TO PERIPHERAL MILLING 被引量:2
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作者 Xu Anping Qu Yunxia Li Weimin School of Mechanical Engineering, Hebei University of Technology Zhang Dawei Huang Tian Tianjin University 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2001年第2期121-126,共6页
Based on analyzing various factors influencing milled surface topography, firstly, a generalized model for milled surface topography is proposed. Secondly, using the principles of transformation matrix and vector oper... Based on analyzing various factors influencing milled surface topography, firstly, a generalized model for milled surface topography is proposed. Secondly, using the principles of transformation matrix and vector operation, the trajectory equation of cutting edge relative to workpiece is derived. Then, a three dimensional topography simulation algorithm is constructed through dividing the workpiece into regular grids. Finally, taking the peripheral milling process as an example, the generalized model is simplified, and the corresponding simulation examples are given. The results indicate that it is very efficient for the generalized model to be used to analyze and simulate the peripherally milled surface topography. 展开更多
关键词 Generalized simulation model Arbitrary contour mill Peripheral milling process Surface topography
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Modeling and simulation for individualized therapy of amisulpride in Chinese patients with schizophrenia:focus on inter interindi⁃vidual variability,therapeutic reference range and laboratory alert level 被引量:7
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作者 HUANG Shan-qing LI Lu +7 位作者 WANG Zhan-zhang XIAO Tao LI Xiao-lin LIU Shu-jing ZHANG Ming LU Hao-yang WEN Yu-guan SHANG De-wei 《中国药理学与毒理学杂志》 CAS 北大核心 2021年第9期661-662,共2页
OBJECTIVE To explain the high inter-individual variability and the frequency of exceeding the therapeutic reference range and the laboratory alert level of amisulpride,a popula⁃tion pharmacokinetic model in Chinese pa... OBJECTIVE To explain the high inter-individual variability and the frequency of exceeding the therapeutic reference range and the laboratory alert level of amisulpride,a popula⁃tion pharmacokinetic model in Chinese patients with schizophrenia was built based on therapeu⁃tic drug monitoring data to guide individualized therapy.METHODS Plasma concentration data(330 measurements from 121 patients)were ana⁃lyzed using a nonlinear mixed-effects model⁃ing approach with first-order conditional estima⁃tion with interaction(FOCE I).The concentra⁃tions of amisulpride were detected by HPLC-MS/MS.Age,weight,sex,combination medication history and renal function status were evaluated as main covariates.The model was internally val⁃idated using goodness-of-fit,bootstrap and nor⁃malized prediction distribution error.Recom⁃mended dosage regimens for patients with key covariates were estimated on the basis of Monte Carlo simulations and the established model.RESULTS A one-compartment model with first-order absorption and elimination was found to adequately characterize amisulpride concentra⁃tion in Chinese patients with schizophrenia.The population estimates of the apparent volume of distribution(V/F)and apparent clearance(CL/F)were 12.7 L and 1.12 L·h-1,respectively.Age sig⁃nificantly affected the clearance of amisulpride and the final model was as follow:CL/F=1.04×(AGE/32)-0.624(L·h-1).To avoid exceeding the lab⁃oratory alert level(640μg·L-1),the model-based simulation results showed that the recommended dose of amisulpride was no more than 600 mg per day for patients aged 60 years,800 mg per day for those aged 40 years and 1200 mg per day for those aged 20 years,respectively.CON⁃CLUSION Dosage optimization of amisulpride can be carried out according to age to reduce the risk of adverse reactions.The model can be used as a suitable tool for designing individual⁃ized therapy for Chinese patients with schizo⁃phrenia. 展开更多
关键词 AMISULPRIDE population pharmacoki⁃netics therapeutic drug monitoring modeling and simulation individualized therapy
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A Numerical Convex Lens for the State-Discretized Modeling and Simulation of Megawatt Power Electronics Systems as Generalized Hybrid Systems 被引量:6
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作者 Bochen Shi Zhengming Zhao +2 位作者 Yicheng Zhu Zhujun Yu Jiahe Ju 《Engineering》 SCIE EI 2021年第12期1766-1777,共12页
Modeling and simulation have emerged as an indispensable approach to create numerical experiment platforms and study engineering systems.However,the increasingly complicated systems that engineers face today dramatica... Modeling and simulation have emerged as an indispensable approach to create numerical experiment platforms and study engineering systems.However,the increasingly complicated systems that engineers face today dramatically challenge state-of-the-art modeling and simulation approaches.Such complicated systems,which are composed of not only continuous states but also discrete events,and which contain complex dynamics across multiple timescales,are defined as generalized hybrid systems(GHSs)in this paper.As a representative GHS,megawatt power electronics(MPE)systems have been largely integrated into the modern power grid,but MPE simulation remains a bottleneck due to its unacceptable time cost and poor convergence.To address this challenge,this paper proposes the numerical convex lens approach to achieve state-discretized modeling and simulation of GHSs.This approach transforms conventional time-discretized passive simulations designed for pure-continuous systems into state-discretized selective simulations designed for GHSs.When this approach was applied to a largescale MPE-based renewable energy system,a 1000-fold increase in simulation speed was achieved,in comparison with existing software.Furthermore,the proposed approach uniquely enables the switching transient simulation of a largescale megawatt system with high accuracy,compared with experimental results,and with no convergence concerns.The numerical convex lens approach leads to the highly efficient simulation of intricate GHSs across multiple timescales,and thus significantly extends engineers’capability to study systems with numerical experiments. 展开更多
关键词 Generalized hybrid systems Megawatt power electronics modeling and simulation Numerical convex lens
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A review of modeling,simulation,and control technologies of altitude ground test facilities for control application 被引量:5
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作者 Xitong PEI Xi WANG +6 位作者 Jiashuai LIU Meiyin ZHU Zhihong DAN Ai HE Keqiang MIAO Louyue ZHANG Zheng XU 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2023年第9期38-62,共25页
As the pivotal test equipment of aero-engines design,finalization,improvement,modification,etc.,the Altitude Ground Test Facilities(AGTF)plays an important role in the research and development of the aero-engines.With... As the pivotal test equipment of aero-engines design,finalization,improvement,modification,etc.,the Altitude Ground Test Facilities(AGTF)plays an important role in the research and development of the aero-engines.With the rapid development of advanced high-performance aeroengine,the increasing demand of high-altitude simulation test is driving AGTF to improve its test ability and level of automation and intelligence.The modeling method,simulation tool,and control technology are the key factors to support the improvement of the AGTF control system.The main purpose of this paper is to provide an overview of modeling methods,simulation tools,and control technologies in AGTF control system for future research.First,it reviews the evolution of AGTF in the world,from the early formative stage to integration stage.Then,the mathematical modeling method of AGTF for control application is overviewed.Furthermore,the simulation tools used in the AGTF control system are overviewed from numerical simulation to hardware-in-loop simulation and further to semi-physical simulation.Meanwhile,the control technologies used in the AGTF control system are summarized from single-variable control to multivariable integrated control,and from classical control theory to modern control theory.Finally,recommendations for future research are outlined.Therefore,this review article provides extensive literature information for the modeling,simulation,and control design of AGTF for control application. 展开更多
关键词 Altitude ground test facilities Control system modeling and simulation Robust control Temperature and pressure control
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Assessing Drought Vulnerability of Bulgarian Agriculture through Model Simulations 被引量:2
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作者 Zomitsa Popova Maria Ivanova +4 位作者 Luis Santos Pereira Vesselin Alexandrov Katerina Doneva Petra Alexandrova Milena Kercheva 《Journal of Environmental Science and Engineering(B)》 2012年第8期1017-1036,共20页
This study assesses vulnerability of agriculture to drought, using WINISAREG model and seasonal SPI2-index for eight climate regions (1951-2004). Results relative to Plovdiv show that in soils of large TAW (total a... This study assesses vulnerability of agriculture to drought, using WINISAREG model and seasonal SPI2-index for eight climate regions (1951-2004). Results relative to Plovdiv show that in soils of large TAW (total available water) net irrigation requirements NIRs range from 0 to 380 mm. In soils of small TAW, NIRs reach 440 mm in the very dry year. NIRs in Sofia/Silistra are about 100 mm smaller than in Plovdiv while in Sandanski they are 30-110 mm larger. Rainfed maize is associated with great yield variability (29% 〈 Cv 〈 72%). Considering an economical RYD (relative yield decrease) threshold, 32% of years are risky when TA Wis large in Plovdiv that is double than in Sofia and half than in Sandanski. In North Bulgaria the risky years are 10% in Pleven/Silistra that is half than in Lom. In Plovdiv region reliable relationships (R2 〉 91%) were found relating the SPI2 "July-Aug." with simulated RYD of rainfed maize while remaining relationships were less accurate (73% 〈 R2 〈 86%). Economical losses are produced when High Peak Season SPI2 〈 + 0.20 in Sandanski, SPI2 〈 - 0.50 in Plovdiv and SPI2 〈 - 0.90 in Sofia. In North Bulgaria the SPI2 threshold ranges from - 0.75 to - 1.50. Derived reliable relationships and SPl-thresholds are used for drought vulnerability mapping. 展开更多
关键词 Drought vulnerability MAIZE ISAREG simulation model SPI-index drought vulnerability mapping.
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