The purpose of this study was to evaluate the long time antibacterial properties and shear bond strength of experimental nano silver-containing cements （NSC）. Nano silver base inorganic antibacterial powder was adde...The purpose of this study was to evaluate the long time antibacterial properties and shear bond strength of experimental nano silver-containing cements （NSC）. Nano silver base inorganic antibacterial powder was added to the reinforced glass ionomer cement at five different weight ratios to obtain a series of nano silver-containing cements, then the antibacterial properties of three orthodontic cement products and five NSC samples were evaluated by the direct contact test （DCT） and the agar diffusion test （ADT）. The DCT, which was based on turbidness determination of bacterial growth in 96-well microtiter plates, was performed in both fresh and aged for 1 day, 1 week, 2 weeks, 3 weeks, 4 weeks, 6 weeks, and 8 weeks tested materials. The shear bond strengthes of three orthodontic cement products and five NSC samples were examined using a universal testing machine. The ADT results indicated that there were no significant differences between NSCs and ORTHO LC fresh specimens. In the DCT experiment, all fresh silver nanoparticles-containing tested samples presented powerful antibacterial properties, but they gradually lost the effective antimicrobial agents with the extension of aging time. Finally, none of the tested materials maintained its antibacterial property after aging for 8 weeks. A gradually decreasing trend of bond strength presented with the increasing incorporation of nano silver base inorganic antibacterial powder into the glass ionomer cement, even though all the tested material specimens reached the ideal bond strength range. We may conclude that NSCs can contribute to decrease the demineralization rate around brackets without compromising bond strength.展开更多
The purpose of this study was to evaluate the antibacterial properties of experimental nano silver-containing cements（NSCs） using rat caries disease model. Nano silver base inorganic antibacterial powder was added t...The purpose of this study was to evaluate the antibacterial properties of experimental nano silver-containing cements（NSCs） using rat caries disease model. Nano silver base inorganic antibacterial powder was added to the reinforced glass ionomer cement at three different weight ratios to obtain a series of nano silver-containing cements, then two orthodontic cement products and three NSC samples were implanted into rat caries disease model, and their antibacterial properties were evaluated by the scanning electron microscope（SEM）. Moreover, the rat caries disease model were established by inoculating cariogenic bacteria S mutans into antibiotics treated rat mouths and feeding with cariogenic diet. The tested materials were bonded on the surface of the buccal half crowns of the upper fi rst premolar, and then fi xed under the rats＇ front teeth lingual side to acquire enough retention. The SEM results indicated that the growth of streptococcus mutans was very active in group of Transbond XT. One month later, S mutans scattered on the GC Fuji ORTHO LC surface, and then the number signifi cantly increased and arranged in chains after three months. In groups of NSC2, NSC3 and NSC4, the number of S mutans presented the downward trend and tended to disperse individually with the increase of silver nanoparticle content. We may conclude that the incorporation of silver nanoparticle enhanced GC Fuji ORTHO LC the adhesion restrain and killing effect to S mutans.展开更多
Silver-containing dressings have gained popularity in clinical applications due to their exceptional antibacterial properties and ability to enhance wound healing.These dressings primarily exert their antibacterial ef...Silver-containing dressings have gained popularity in clinical applications due to their exceptional antibacterial properties and ability to enhance wound healing.These dressings primarily exert their antibacterial effects through the utilization of silver ions or nano-silver particles.The antimicrobial property of silver ions is a result of multiple mechanisms,with the most significant being the interaction between Ag or Ag+and the bacterial cell wall,as well as the interaction between Ag+and bacterial DNA or RNA,which inhibits replication and division.Silver-containing dressings can effectively reduce inflammation in wound tissue and expedite wound healing.The antibacterial and wound-healing promoting effects of these dressings are closely associated with the controlled release rate of silver ions.Consequently,developing novel silver-containing dressings that accurately regulate this release rate has become a prominent area of research interest.With broad prospects for application in wound care,silver-containing dressings are anticipated to offer innovative solutions for addressing numerous challenges encountered in clinical wound management.展开更多
基金Funded by the Natural Science Foundation of Hubei Province(No.2012FFB04416)
文摘The purpose of this study was to evaluate the long time antibacterial properties and shear bond strength of experimental nano silver-containing cements （NSC）. Nano silver base inorganic antibacterial powder was added to the reinforced glass ionomer cement at five different weight ratios to obtain a series of nano silver-containing cements, then the antibacterial properties of three orthodontic cement products and five NSC samples were evaluated by the direct contact test （DCT） and the agar diffusion test （ADT）. The DCT, which was based on turbidness determination of bacterial growth in 96-well microtiter plates, was performed in both fresh and aged for 1 day, 1 week, 2 weeks, 3 weeks, 4 weeks, 6 weeks, and 8 weeks tested materials. The shear bond strengthes of three orthodontic cement products and five NSC samples were examined using a universal testing machine. The ADT results indicated that there were no significant differences between NSCs and ORTHO LC fresh specimens. In the DCT experiment, all fresh silver nanoparticles-containing tested samples presented powerful antibacterial properties, but they gradually lost the effective antimicrobial agents with the extension of aging time. Finally, none of the tested materials maintained its antibacterial property after aging for 8 weeks. A gradually decreasing trend of bond strength presented with the increasing incorporation of nano silver base inorganic antibacterial powder into the glass ionomer cement, even though all the tested material specimens reached the ideal bond strength range. We may conclude that NSCs can contribute to decrease the demineralization rate around brackets without compromising bond strength.
基金Funded by the Natural Science Foundation of Hubei Province(No.2012FFB04416)
文摘The purpose of this study was to evaluate the antibacterial properties of experimental nano silver-containing cements（NSCs） using rat caries disease model. Nano silver base inorganic antibacterial powder was added to the reinforced glass ionomer cement at three different weight ratios to obtain a series of nano silver-containing cements, then two orthodontic cement products and three NSC samples were implanted into rat caries disease model, and their antibacterial properties were evaluated by the scanning electron microscope（SEM）. Moreover, the rat caries disease model were established by inoculating cariogenic bacteria S mutans into antibiotics treated rat mouths and feeding with cariogenic diet. The tested materials were bonded on the surface of the buccal half crowns of the upper fi rst premolar, and then fi xed under the rats＇ front teeth lingual side to acquire enough retention. The SEM results indicated that the growth of streptococcus mutans was very active in group of Transbond XT. One month later, S mutans scattered on the GC Fuji ORTHO LC surface, and then the number signifi cantly increased and arranged in chains after three months. In groups of NSC2, NSC3 and NSC4, the number of S mutans presented the downward trend and tended to disperse individually with the increase of silver nanoparticle content. We may conclude that the incorporation of silver nanoparticle enhanced GC Fuji ORTHO LC the adhesion restrain and killing effect to S mutans.
基金Key Scientific Research Project of Universities in Henan Province(22A530005).
文摘Silver-containing dressings have gained popularity in clinical applications due to their exceptional antibacterial properties and ability to enhance wound healing.These dressings primarily exert their antibacterial effects through the utilization of silver ions or nano-silver particles.The antimicrobial property of silver ions is a result of multiple mechanisms,with the most significant being the interaction between Ag or Ag+and the bacterial cell wall,as well as the interaction between Ag+and bacterial DNA or RNA,which inhibits replication and division.Silver-containing dressings can effectively reduce inflammation in wound tissue and expedite wound healing.The antibacterial and wound-healing promoting effects of these dressings are closely associated with the controlled release rate of silver ions.Consequently,developing novel silver-containing dressings that accurately regulate this release rate has become a prominent area of research interest.With broad prospects for application in wound care,silver-containing dressings are anticipated to offer innovative solutions for addressing numerous challenges encountered in clinical wound management.
