Bi/Bi_(2)Fe_(4)O_(9)nanocomposites consisting of Bi_(2)Fe_(4)O_(9)nanosheets decorated with Bi nanodots were synthesized by a hydrothermal method.The formation of Bi nanodots on the Bi_(2)Fe_(4)O_(9)nanosheet surfaces...Bi/Bi_(2)Fe_(4)O_(9)nanocomposites consisting of Bi_(2)Fe_(4)O_(9)nanosheets decorated with Bi nanodots were synthesized by a hydrothermal method.The formation of Bi nanodots on the Bi_(2)Fe_(4)O_(9)nanosheet surfaces was attributed to the reducibility of 2-methoxyethanol in the precursor solution.Comparative photocatalytic evaluation reveals that the Bi/Bi_(2)Fe_(4)O_(9)nanocomposites significantly enhance the degradation efficiency(99.0%)of bisphenol A compared with Bi_(2)Fe_(4)O_(9)nanosheets(64.2%)under 120 min simulated solar irradiation.This remarkable enhancement can be attributed to the established Bi/Bi_(2)Fe_(4)O_(9)heterojunction structure,which effectively facilitates the separation of photogenerated electron-hole pairs and accelerates interfacial charge transfer between the metallic Bi nanodots and semiconductor Bi_(2)Fe_(4)O_(9)nanosheets.The synergistic effects arising from this unique architecture ultimately lead to superior photocatalytic performance.展开更多
Zn-based thermal charging devices,utilizing the synergistic effect of ion thermoextraction and thermodiffusion,are able to efficiently convert thermal energy into electrical energy and storage in the devices,making th...Zn-based thermal charging devices,utilizing the synergistic effect of ion thermoextraction and thermodiffusion,are able to efficiently convert thermal energy into electrical energy and storage in the devices,making them a highly promising technology for low-grade heat recovery and utilization.However,the low output power density and energy conversion efficiency resulted by the slow diffusion kinetics of Zn^(2+)hinder their development.Herein,we present a highperformance thermal charging cell design using Zn^(2+)/NH_(4)^(+)hybrid ion electrolyte,which not only maintains the high output voltage of the Zn-based thermoelectric system,but also significantly enhances the output power density due to the fast diffusion kinetics of NH_(4)^(+).Based on this strategy,the thermal charging cell displays a high thermopower of 12.5 mV K^(-1)and an excellent normalized power density of 19.6 mW m^(-2)K^(-2)at a temperature difference of 35 K.The Carnot-relative efficiency is as high as 12.74%.Moreover,it can operate continuously for over 72 h when the temperature difference persists,achieving a balance between thermoelectric conversion and output.This work provides a simple and effective strategy for the design of high-performance thermal charging cells for low-grade heat conversion and utilization.展开更多
A comparative study on the corrosion resistance of 17Ni/（NiFe2O4-10NiO） cermet inert anode prepared in differentsintering atmospheres was conducted in Na3AlF6-Al2O3 melt. The results indicate that the corrosion rate...A comparative study on the corrosion resistance of 17Ni/（NiFe2O4-10NiO） cermet inert anode prepared in differentsintering atmospheres was conducted in Na3AlF6-Al2O3 melt. The results indicate that the corrosion rates of NiFe2O4-based cermetanodes prepared in the vacuum and the atmosphere with oxygen content of 2×10^-3 （volume fraction） are 6.46 and 2.71 cm/a,respectively. Though there is a transition layer with lots of holes or pores, a densified layer is formed on the surface of anode due tosome reactions producing aluminates. For the anode prepared in the atmosphere with oxygen content of 2×10^-3, the thickness of thedensification layer （about 50 μm） is thicker than that （about 30 μm） formed on the surface of anode prepared in the vacuum. Thecontents of NiO and Fe（II） in NiFe2xO4-y-z increase with the decrease of oxygen content in sintering atmosphere, which reduces thecorrosion resistance of the material.展开更多
NiFe2O4-10NiO-based cermet inert anodes for aluminium electrolysis were prepared and their properties were investigated in a lab-scale electrolysis cell. The results show that the inert anodes exhibit good performance...NiFe2O4-10NiO-based cermet inert anodes for aluminium electrolysis were prepared and their properties were investigated in a lab-scale electrolysis cell. The results show that the inert anodes exhibit good performance during electrolysis in molten salt cryolite at 960 °C, but according to the analyses of phase compositions and microstructures through XRD, SEM/EDX and metallographic analysis, the metal in the anodes is preferentially corroded and many pores are produced on the anode surface after electrolysis. The preferential dissolution of Fe in the NiFe2O4 phase may lead to the non-uniform corrosion of NiFe2O4 grains. Moreover, a dense protective layer of NiFe2O4-NiAl2O4-FeAl2O4 is formed on the anode surface, which originates from the reaction of Al2O3 dissolved in the electrolyte with NiO or FeO, the annexation of NiFe2O4-NiAl2O4-FeAl2O4 to NiO and volume expansion. Thus, the dense NiFe2O4-NiAl2O4-FeAl2O4 layer inhibits the metal loss and ceramic-phase corrosion on the surface of the cermet inert anodes.展开更多
Background:Terpinen-4-ol(T4O),a key constituent of tea tree essential oil and various aromatic plants,has shown promising antiproliferative and pro-apoptotic effects in melanoma and other cancer types.However,its effi...Background:Terpinen-4-ol(T4O),a key constituent of tea tree essential oil and various aromatic plants,has shown promising antiproliferative and pro-apoptotic effects in melanoma and other cancer types.However,its efficacy against cutaneous squamous cell carcinoma(cSCC)remains unclear.Thus,in this study,we investigated the in vivo and in vitro effects of T4O on cSCC cell lines and preliminarily explored its impacting pathways.Methods:Using CCK8 and assay colony formation,we assessed the viability of cSCC A431,SCL-1,and COLO-16 cells treated with T40 at varying concentrations(0,1,2,and 4μM).Flow cytometry was employed to evaluate T4O’s effect on cSCC cell’s cycle progression and apoptosis induction.Additionally,western blotting was utilized to examine the expression intensities of N-cadherin and E-cadherin,two indicative markers of the epithelial-mesenchymal transition(EMT)pathway.T4O’s in vivo effect on inhibiting tumor progression was evaluated on an established xenograft tumor model.Then,the molecular mechanisms of T4O’s antitumor effect were explored by an integrated genome-wide transcriptomics and proteomics study on cSCC A431c cells.Finally,calpain-2’s potential mediator role in T4O’s anti-tumor mechanism was investigated in calpain-2 knockdown cell lines prepared via siRNA transfection.Result:It’s demonstrated that T4O treatment inhibited cSCC proliferation,clonogenicity,migration,and invasion while inducing apoptosis and suppressing the EMT pathway.T4O administration also inhibited cSCC tumorigenesis in the xenograft tumor model.RNA-sequencing and iTRAQ analysis detected significant upregulation of calpain-2 expression in T4O-treated cSCC cells.Western blotting confirmed that T4O significantly increased calpain-2 expression and promoted proteolytic cleavage ofβ-catenin and caspase-12,two calpain-2 target proteins.Importantly,siRNA-mediated calpain-2 knockdown relieved T4O’s suppressive effect on cSCC cell proliferation and motility.Mechanistically,T4O upregulates calpain-2 expression and promotes the cleavage ofβ-catenin and caspase-12,with siRNA-mediated calpain-2 knockdown mitigating T4O’s suppressive effects.Conclusion:These findings suggest that T4O’s antitumor activity in cSCC is mediated through the upregulation of calpain-2 expression and subsequent modulation ofβ-catenin and caspase-12.展开更多
（Cu-Ni）/（10NiO-90NiFe204） cermet inert anodes containing metal Cu-Ni0, 5, 10, 15 and 20 wt pct were prepared and their corrosion resistance to Na3AlF6-Al2O3 melts was investigated. The results indicate that the co...（Cu-Ni）/（10NiO-90NiFe204） cermet inert anodes containing metal Cu-Ni0, 5, 10, 15 and 20 wt pct were prepared and their corrosion resistance to Na3AlF6-Al2O3 melts was investigated. The results indicate that the content of metal Cu-Ni has little effect on the steady-state concentration of Ni in the electrolyte and the values could not be used to effectively differentiate their corrosion resistance. The steady-state concentration of Fe decreases from 304×10^-6 to 168×10^-6 and that of Cu increases from 21×10^-6 to 71×10^-6 with the content of metal Cu-Ni increasing from 0 to 20 wt pct. Post-examination shows that metallic phase Cu-Ni is corroded preferentially during electrolysis and many pores are left at the anode surface. Considering the corrosion resistance and electrical conductivity, the cermet containing metal Cu-Ni 5 wt pct should be selected and studied further.展开更多
NiFe2O4-based cermet inert anodes with metallic phase compositions of Cu, Ni and 85Cu15Ni were prepared by cold pressing-sintering. Their corrosion resistance was also investigated in Na3 AIF6-Al2O3 melts. The resuits...NiFe2O4-based cermet inert anodes with metallic phase compositions of Cu, Ni and 85Cu15Ni were prepared by cold pressing-sintering. Their corrosion resistance was also investigated in Na3 AIF6-Al2O3 melts. The resuits show that the metallic phase species in cermets have no effect on the concentration of impurities in bath during electrolysis, the total steady-state concentration of impurities is almost the same, i.e. between 4.12 × 10^-4- 4.80 × 10^-4. There exists metal preferential corrosion for the cermet inert anode with metal Ni as metallic phase. For NiFe2 O4-based cermets, the cermet with metal Cu as metallic phase exhibits better corrosion resistance than the others.展开更多
Ni-xNiO-NiFe2O4 cermets with different NiO contents were prepared and the corrosion behaviour in Na3AlF6-Al2O3 melts was investigated in laboratory electrolysis tests. The results indicate that adding NiO is （un-）（...Ni-xNiO-NiFe2O4 cermets with different NiO contents were prepared and the corrosion behaviour in Na3AlF6-Al2O3 melts was investigated in laboratory electrolysis tests. The results indicate that adding NiO is （un-）（favorable） to the densification of NiFe2O4-xNiO ceramics, while small Ni doping can greatly improve the sintering property. The electrolysis tests show that excess NiO is beneficial to the reduction of Fe while has little effects on that of Ni in the bath; the steady-state concentrations of Ni, Fe are below the corresponding solubilities of NiFe2O4-xNiO, implying that corrosion mechanism changes while electrifying. Post-electrolysis examination of anodes shows that Ni metal leaches at the anode surface, yet the substrate ceramic prevents the penetration of bath and the further loss of metal phase.展开更多
基金Funded by the National Natural Science Foundation of China(No.50902108)。
文摘Bi/Bi_(2)Fe_(4)O_(9)nanocomposites consisting of Bi_(2)Fe_(4)O_(9)nanosheets decorated with Bi nanodots were synthesized by a hydrothermal method.The formation of Bi nanodots on the Bi_(2)Fe_(4)O_(9)nanosheet surfaces was attributed to the reducibility of 2-methoxyethanol in the precursor solution.Comparative photocatalytic evaluation reveals that the Bi/Bi_(2)Fe_(4)O_(9)nanocomposites significantly enhance the degradation efficiency(99.0%)of bisphenol A compared with Bi_(2)Fe_(4)O_(9)nanosheets(64.2%)under 120 min simulated solar irradiation.This remarkable enhancement can be attributed to the established Bi/Bi_(2)Fe_(4)O_(9)heterojunction structure,which effectively facilitates the separation of photogenerated electron-hole pairs and accelerates interfacial charge transfer between the metallic Bi nanodots and semiconductor Bi_(2)Fe_(4)O_(9)nanosheets.The synergistic effects arising from this unique architecture ultimately lead to superior photocatalytic performance.
基金supported by the Leading Edge Technology of Jiangsu Province(BK20222009-X.Z.,BK20202008-X.Z.)Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)National Undergraduate Innovation Training Program of NUAA(202410287179Y).
文摘Zn-based thermal charging devices,utilizing the synergistic effect of ion thermoextraction and thermodiffusion,are able to efficiently convert thermal energy into electrical energy and storage in the devices,making them a highly promising technology for low-grade heat recovery and utilization.However,the low output power density and energy conversion efficiency resulted by the slow diffusion kinetics of Zn^(2+)hinder their development.Herein,we present a highperformance thermal charging cell design using Zn^(2+)/NH_(4)^(+)hybrid ion electrolyte,which not only maintains the high output voltage of the Zn-based thermoelectric system,but also significantly enhances the output power density due to the fast diffusion kinetics of NH_(4)^(+).Based on this strategy,the thermal charging cell displays a high thermopower of 12.5 mV K^(-1)and an excellent normalized power density of 19.6 mW m^(-2)K^(-2)at a temperature difference of 35 K.The Carnot-relative efficiency is as high as 12.74%.Moreover,it can operate continuously for over 72 h when the temperature difference persists,achieving a balance between thermoelectric conversion and output.This work provides a simple and effective strategy for the design of high-performance thermal charging cells for low-grade heat conversion and utilization.
基金Project(51474238)supported by the National Natural Science Foundation of China
文摘A comparative study on the corrosion resistance of 17Ni/（NiFe2O4-10NiO） cermet inert anode prepared in differentsintering atmospheres was conducted in Na3AlF6-Al2O3 melt. The results indicate that the corrosion rates of NiFe2O4-based cermetanodes prepared in the vacuum and the atmosphere with oxygen content of 2×10^-3 （volume fraction） are 6.46 and 2.71 cm/a,respectively. Though there is a transition layer with lots of holes or pores, a densified layer is formed on the surface of anode due tosome reactions producing aluminates. For the anode prepared in the atmosphere with oxygen content of 2×10^-3, the thickness of thedensification layer （about 50 μm） is thicker than that （about 30 μm） formed on the surface of anode prepared in the vacuum. Thecontents of NiO and Fe（II） in NiFe2xO4-y-z increase with the decrease of oxygen content in sintering atmosphere, which reduces thecorrosion resistance of the material.
基金Project (2012FJ6123) supported by the Project of Science and Technology of Hunan Province,ChinaProject supported by Post-Doctoral Foundation of Central South University,China+1 种基金Project (CL12100) supported the Undergraduate Innovative Training of Central South University,ChinaProject (2282013bkso13) supported by Free Exploration Plan of Central South University,China
文摘NiFe2O4-10NiO-based cermet inert anodes for aluminium electrolysis were prepared and their properties were investigated in a lab-scale electrolysis cell. The results show that the inert anodes exhibit good performance during electrolysis in molten salt cryolite at 960 °C, but according to the analyses of phase compositions and microstructures through XRD, SEM/EDX and metallographic analysis, the metal in the anodes is preferentially corroded and many pores are produced on the anode surface after electrolysis. The preferential dissolution of Fe in the NiFe2O4 phase may lead to the non-uniform corrosion of NiFe2O4 grains. Moreover, a dense protective layer of NiFe2O4-NiAl2O4-FeAl2O4 is formed on the anode surface, which originates from the reaction of Al2O3 dissolved in the electrolyte with NiO or FeO, the annexation of NiFe2O4-NiAl2O4-FeAl2O4 to NiO and volume expansion. Thus, the dense NiFe2O4-NiAl2O4-FeAl2O4 layer inhibits the metal loss and ceramic-phase corrosion on the surface of the cermet inert anodes.
基金supported by the Basic Research Program of the Guizhou Science Cooperation Foundation Project(Grant Number:ZK[2021]466)Guizhou Provincial Health Commission(Grant Number:gzwkj2022-062).
文摘Background:Terpinen-4-ol(T4O),a key constituent of tea tree essential oil and various aromatic plants,has shown promising antiproliferative and pro-apoptotic effects in melanoma and other cancer types.However,its efficacy against cutaneous squamous cell carcinoma(cSCC)remains unclear.Thus,in this study,we investigated the in vivo and in vitro effects of T4O on cSCC cell lines and preliminarily explored its impacting pathways.Methods:Using CCK8 and assay colony formation,we assessed the viability of cSCC A431,SCL-1,and COLO-16 cells treated with T40 at varying concentrations(0,1,2,and 4μM).Flow cytometry was employed to evaluate T4O’s effect on cSCC cell’s cycle progression and apoptosis induction.Additionally,western blotting was utilized to examine the expression intensities of N-cadherin and E-cadherin,two indicative markers of the epithelial-mesenchymal transition(EMT)pathway.T4O’s in vivo effect on inhibiting tumor progression was evaluated on an established xenograft tumor model.Then,the molecular mechanisms of T4O’s antitumor effect were explored by an integrated genome-wide transcriptomics and proteomics study on cSCC A431c cells.Finally,calpain-2’s potential mediator role in T4O’s anti-tumor mechanism was investigated in calpain-2 knockdown cell lines prepared via siRNA transfection.Result:It’s demonstrated that T4O treatment inhibited cSCC proliferation,clonogenicity,migration,and invasion while inducing apoptosis and suppressing the EMT pathway.T4O administration also inhibited cSCC tumorigenesis in the xenograft tumor model.RNA-sequencing and iTRAQ analysis detected significant upregulation of calpain-2 expression in T4O-treated cSCC cells.Western blotting confirmed that T4O significantly increased calpain-2 expression and promoted proteolytic cleavage ofβ-catenin and caspase-12,two calpain-2 target proteins.Importantly,siRNA-mediated calpain-2 knockdown relieved T4O’s suppressive effect on cSCC cell proliferation and motility.Mechanistically,T4O upregulates calpain-2 expression and promotes the cleavage ofβ-catenin and caspase-12,with siRNA-mediated calpain-2 knockdown mitigating T4O’s suppressive effects.Conclusion:These findings suggest that T4O’s antitumor activity in cSCC is mediated through the upregulation of calpain-2 expression and subsequent modulation ofβ-catenin and caspase-12.
基金financial support from National Basic Research Program of China(No.2005CB623703)National Natural Science Foundation of China(No.50474051).
文摘（Cu-Ni）/（10NiO-90NiFe204） cermet inert anodes containing metal Cu-Ni0, 5, 10, 15 and 20 wt pct were prepared and their corrosion resistance to Na3AlF6-Al2O3 melts was investigated. The results indicate that the content of metal Cu-Ni has little effect on the steady-state concentration of Ni in the electrolyte and the values could not be used to effectively differentiate their corrosion resistance. The steady-state concentration of Fe decreases from 304×10^-6 to 168×10^-6 and that of Cu increases from 21×10^-6 to 71×10^-6 with the content of metal Cu-Ni increasing from 0 to 20 wt pct. Post-examination shows that metallic phase Cu-Ni is corroded preferentially during electrolysis and many pores are left at the anode surface. Considering the corrosion resistance and electrical conductivity, the cermet containing metal Cu-Ni 5 wt pct should be selected and studied further.
基金Project(2005CB623703) supported by the National Basic Research Programof China project(03JJY3080) supported bythe Hunan Provincial Natural Science Foundation
文摘NiFe2O4-based cermet inert anodes with metallic phase compositions of Cu, Ni and 85Cu15Ni were prepared by cold pressing-sintering. Their corrosion resistance was also investigated in Na3 AIF6-Al2O3 melts. The resuits show that the metallic phase species in cermets have no effect on the concentration of impurities in bath during electrolysis, the total steady-state concentration of impurities is almost the same, i.e. between 4.12 × 10^-4- 4.80 × 10^-4. There exists metal preferential corrosion for the cermet inert anode with metal Ni as metallic phase. For NiFe2 O4-based cermets, the cermet with metal Cu as metallic phase exhibits better corrosion resistance than the others.
文摘Ni-xNiO-NiFe2O4 cermets with different NiO contents were prepared and the corrosion behaviour in Na3AlF6-Al2O3 melts was investigated in laboratory electrolysis tests. The results indicate that adding NiO is （un-）（favorable） to the densification of NiFe2O4-xNiO ceramics, while small Ni doping can greatly improve the sintering property. The electrolysis tests show that excess NiO is beneficial to the reduction of Fe while has little effects on that of Ni in the bath; the steady-state concentrations of Ni, Fe are below the corresponding solubilities of NiFe2O4-xNiO, implying that corrosion mechanism changes while electrifying. Post-electrolysis examination of anodes shows that Ni metal leaches at the anode surface, yet the substrate ceramic prevents the penetration of bath and the further loss of metal phase.
