The influence of electro-acupuncture at Neiguan (PC 6)and five shu points of twelve regular meridians at different time on systolic time interval (ST I) of normal young adultswere studied with 6×6 Latin square de...The influence of electro-acupuncture at Neiguan (PC 6)and five shu points of twelve regular meridians at different time on systolic time interval (ST I) of normal young adultswere studied with 6×6 Latin square design in this work.In 12 groups according to 12 regular merldlans,the STIs were measured respectively just before and after electro-acupuncture on Neiguan andfive shu points at 00:00,04:00,08:00,12:00,16:00 and 20:00 of a day.It was found thatexcept the PEPI and PEPI/LVETI ratio among Shenmen(HT 7),Shaochong(HT 9)and Neiguan,Guanchong(TE)and Yemen(TE 2)points,the effects of electro-acupuncture at Neiguan pointand five shu points of twelve regular meridians on the indices of STI of normal young adults wereshowing no slgnificant differences.There also was no difference in different sex.But the indices ofSTI were changed when electroacupuncture on the different points of different meridians at differenttime.展开更多
OBJECTIVE: To investigate the effects of needling the Shu, Yuan, and Mu acupoints on serum uric acid(SUA), xanthine oxidase(XOD), and alkaline phosphatase(ALP) levels and the kidney index in a rat model of gout and hy...OBJECTIVE: To investigate the effects of needling the Shu, Yuan, and Mu acupoints on serum uric acid(SUA), xanthine oxidase(XOD), and alkaline phosphatase(ALP) levels and the kidney index in a rat model of gout and hyperuricemia.METHODS: Fifty rats were randomly divided into five groups: blank, model, Shu-acupoint, Yuan-acupoint, and Mu-acupoint groups. A rat model of hyperuricemia was developed by intragastric administration of adenine and ethambutol. This experiment last for 90 d in total. Treatment groups underwent 3 courses of acupuncture. Each course involved a total of 10 interventions(one intervention every second day) with each intervention lasting15 min. There was a break for 10 d between courses. SUA and ALP were analyzed using an automatic biochemical analyzer and XOD was analyzed using immunofluorescence.RESULTS: Compared with the blank group, SUA and XOD levels in the model group were significantly higher and the renal index significantly improved. Compared with the model group, SUA and XOD levels in the three treatment groups decreased and the renal index significantly improved.When the three treatment groups were compared,the Mu-acupoint group showed the greatest decreases in SUA and XOD levels, followed by the Yuan-acupoint group. There was no significant difference in kidney index among the three treatment groups. There was no significant difference in ALP levels among the groups.CONCLUSION: The three treatments showed significantly reduced SUA and XOD levels compared with the control groups, possibly suggesting reduced renal damage.展开更多
OBJECTIVE:To observe the effects of bloodletting puncture at Jing-Well points in the distal ends of the finger and toe on survival rate,survival time,and brain edema in rats with cerebral ischemia.METHODS:Fifty-four m...OBJECTIVE:To observe the effects of bloodletting puncture at Jing-Well points in the distal ends of the finger and toe on survival rate,survival time,and brain edema in rats with cerebral ischemia.METHODS:Fifty-four male Sprague-Dawley rats were randomly divided into five groups:normal,sham operation,model,bloodletting puncture at Jing-Well points in distal ends of finger and toe,and puncture without bloodletting at these points.Middle cerebral artery occlusion models were established according to Longa's method.The brains were taken 48 h after the model was established.Brain water content,brain density,brain coefficient,survival rate,and survival time in each group were measured.RESULTS:After bloodletting puncture,the survival time of the rats was prolonged,their brain water content and brain coefficient were reduced,and brain density was increased.CONCLUSION:Bloodletting puncture at Jing-Well points in the distal ends of the finger and toe can improve function in ischemic brain edema.展开更多
[目的]基于“以俞调枢”理论探讨艾灸背俞穴预防恶性肿瘤患者化疗相关性恶心呕吐(chemotherapy-induced nausea and vomiting,CINV)的临床疗效。[方法]选取浙江中医药大学附属第一医院2021年9月至2023年12月接受化疗的恶性肿瘤患者94例...[目的]基于“以俞调枢”理论探讨艾灸背俞穴预防恶性肿瘤患者化疗相关性恶心呕吐(chemotherapy-induced nausea and vomiting,CINV)的临床疗效。[方法]选取浙江中医药大学附属第一医院2021年9月至2023年12月接受化疗的恶性肿瘤患者94例,通过随机数字表法分为试验组和对照组,每组各47例。对照组患者接受常规治疗及护理,试验组在常规治疗护理的基础上接受艾灸背俞穴治疗。比较两组患者在化疗后第1~5天、第7天及第14天恶心、呕吐发生率,以及化疗相关药物不良反应(便秘、头痛、疲乏、嗜睡)的发生率。[结果]化疗后第1~2天,试验组恶心发生率低于对照组,但差异无统计学意义(P>0.05);而化疗后第3~5天及第7天,试验组的恶心发生率显著低于对照组(P<0.05)。化疗后第2~5天及第7天,试验组的呕吐发生率亦低于对照组(P<0.05)。试验组化疗相关不良反应便秘、头痛、疲乏及嗜睡等发生率分别为23.4%、4.3%、34.0%和10.6%,均低于对照组,差异有统计学意义(P<0.05)。[结论]艾灸背俞穴可作为辅助治疗,降低恶性肿瘤患者化疗过程中恶心呕吐症状的发生率,同时也能减轻由化疗相关药物引起的其他不良反应。展开更多
基金Supported by National Natural Science Foundation of China
文摘The influence of electro-acupuncture at Neiguan (PC 6)and five shu points of twelve regular meridians at different time on systolic time interval (ST I) of normal young adultswere studied with 6×6 Latin square design in this work.In 12 groups according to 12 regular merldlans,the STIs were measured respectively just before and after electro-acupuncture on Neiguan andfive shu points at 00:00,04:00,08:00,12:00,16:00 and 20:00 of a day.It was found thatexcept the PEPI and PEPI/LVETI ratio among Shenmen(HT 7),Shaochong(HT 9)and Neiguan,Guanchong(TE)and Yemen(TE 2)points,the effects of electro-acupuncture at Neiguan pointand five shu points of twelve regular meridians on the indices of STI of normal young adults wereshowing no slgnificant differences.There also was no difference in different sex.But the indices ofSTI were changed when electroacupuncture on the different points of different meridians at differenttime.
基金Supported by Central Universities Fundamental Research Funds Project(Graduate Programs)from the Beijing University of Chinese Medicine:Experiment Research on the Effects of Acupuncturing Shu,Yuan,and Mu Acupoints in a Rat Model of Gout and Hyperuricemia(No.2015-JYB-XS127)
文摘OBJECTIVE: To investigate the effects of needling the Shu, Yuan, and Mu acupoints on serum uric acid(SUA), xanthine oxidase(XOD), and alkaline phosphatase(ALP) levels and the kidney index in a rat model of gout and hyperuricemia.METHODS: Fifty rats were randomly divided into five groups: blank, model, Shu-acupoint, Yuan-acupoint, and Mu-acupoint groups. A rat model of hyperuricemia was developed by intragastric administration of adenine and ethambutol. This experiment last for 90 d in total. Treatment groups underwent 3 courses of acupuncture. Each course involved a total of 10 interventions(one intervention every second day) with each intervention lasting15 min. There was a break for 10 d between courses. SUA and ALP were analyzed using an automatic biochemical analyzer and XOD was analyzed using immunofluorescence.RESULTS: Compared with the blank group, SUA and XOD levels in the model group were significantly higher and the renal index significantly improved. Compared with the model group, SUA and XOD levels in the three treatment groups decreased and the renal index significantly improved.When the three treatment groups were compared,the Mu-acupoint group showed the greatest decreases in SUA and XOD levels, followed by the Yuan-acupoint group. There was no significant difference in kidney index among the three treatment groups. There was no significant difference in ALP levels among the groups.CONCLUSION: The three treatments showed significantly reduced SUA and XOD levels compared with the control groups, possibly suggesting reduced renal damage.
基金Supported by High Technology Fund of Japanese Ministry of Education,Culture,Sports,Science and Technology:Clinical and Experimental Research on the Influence of Acupuncture and Chinese Medicine Herb on Recovery of Nerve Ending Damage(No.343) Open Fund Key Projects of Zhejiang Provincial Top Key Discipline of Acupuncture and Massage(No.ZTK2010A07)
文摘OBJECTIVE:To observe the effects of bloodletting puncture at Jing-Well points in the distal ends of the finger and toe on survival rate,survival time,and brain edema in rats with cerebral ischemia.METHODS:Fifty-four male Sprague-Dawley rats were randomly divided into five groups:normal,sham operation,model,bloodletting puncture at Jing-Well points in distal ends of finger and toe,and puncture without bloodletting at these points.Middle cerebral artery occlusion models were established according to Longa's method.The brains were taken 48 h after the model was established.Brain water content,brain density,brain coefficient,survival rate,and survival time in each group were measured.RESULTS:After bloodletting puncture,the survival time of the rats was prolonged,their brain water content and brain coefficient were reduced,and brain density was increased.CONCLUSION:Bloodletting puncture at Jing-Well points in the distal ends of the finger and toe can improve function in ischemic brain edema.
文摘[目的]基于“以俞调枢”理论探讨艾灸背俞穴预防恶性肿瘤患者化疗相关性恶心呕吐(chemotherapy-induced nausea and vomiting,CINV)的临床疗效。[方法]选取浙江中医药大学附属第一医院2021年9月至2023年12月接受化疗的恶性肿瘤患者94例,通过随机数字表法分为试验组和对照组,每组各47例。对照组患者接受常规治疗及护理,试验组在常规治疗护理的基础上接受艾灸背俞穴治疗。比较两组患者在化疗后第1~5天、第7天及第14天恶心、呕吐发生率,以及化疗相关药物不良反应(便秘、头痛、疲乏、嗜睡)的发生率。[结果]化疗后第1~2天,试验组恶心发生率低于对照组,但差异无统计学意义(P>0.05);而化疗后第3~5天及第7天,试验组的恶心发生率显著低于对照组(P<0.05)。化疗后第2~5天及第7天,试验组的呕吐发生率亦低于对照组(P<0.05)。试验组化疗相关不良反应便秘、头痛、疲乏及嗜睡等发生率分别为23.4%、4.3%、34.0%和10.6%,均低于对照组,差异有统计学意义(P<0.05)。[结论]艾灸背俞穴可作为辅助治疗,降低恶性肿瘤患者化疗过程中恶心呕吐症状的发生率,同时也能减轻由化疗相关药物引起的其他不良反应。
