BACKGROUND The six-minute walk test(6MWT)allows to determine,in addition to the main parameters,the time of heart rate recovery(THRR),cardiac function,adaptation index(AI),which characterize the compensatory reserve o...BACKGROUND The six-minute walk test(6MWT)allows to determine,in addition to the main parameters,the time of heart rate recovery(THRR),cardiac function,adaptation index(AI),which characterize the compensatory reserve of patients with chronic heart failure(CHF).At the same time,the significance of these parameters in patients taking beta-blockers for CHF is insufficiently studied,taking into account the negative chronotropic effect of drugs.In this regard,it is relevant to identify factors that can characterize the compensatory capabilities of a patient with CHF during 6MWT,not related to the calculation of heart rate.AIM To identify hemodynamic indicators of the adaptive capabilities of patients with CHF during paired 6MWT depending on their intake of beta-blockers.METHODS Seventy-four patients with compensated CHF due to coronary heart disease and/or hypertension formed the main group,comprising 46 individuals who were taking beta-blockers,and a comparison group comprising 28 individuals who had not been taking beta-blockers for at least one month before 6MWT.All participants underwent Doppler echocardiography(DECG),paired 6MWT,with assessment of hemodynamic parameters before and after both the first and second test.AI,THRR,blood pressure variability(BPV)were calculated.Multivariate,correlation analyses,univariate analysis of variance were used.RESULTS There were no significant associations between adaptation characteristics and DECG parameters or functional class(FC)of CHF in patients of the main group.In the comparison group,the indicators of compensatory reserve were significantly and directly associated with left ventricular ejection fraction(LVEF),and inversely with FC CHF and cardiac cavity size.In both groups,a greater difference in systolic blood pressure between the end of the first and the beginning of the second 6MWT was significantly associated with a higher index of right ventricular systolic dysfunction(Tricuspid annular plane systolic excursion)and LVEF,as well as a smaller left ventricular size and mass,and a lower pulmonary artery systolic pressure in patients in the main group.CONCLUSION Systolic BPV,measured immediately after 6MWT and 20 minutes after its completion,can indirectly characterize the compensatory reserve in patients with CHF,regardless of their beta-blocker intake.展开更多
The aim of this study was to understand the characteristics of blood pressure (BP) variability in subjects with diabetic nephropathy (DN), and identify the probable predictors affecting BP variability. Fifty-one c...The aim of this study was to understand the characteristics of blood pressure (BP) variability in subjects with diabetic nephropathy (DN), and identify the probable predictors affecting BP variability. Fifty-one chronic kidney disease (CKD)-hypertensive patients without diabetes (NDN group) and sixty type 2 diabetic patients with overt DN (DN group) were enrolled in this study. The values of short-term BP variability were obtained from 24 h ambulatory BP monitoring (ABPM). Variance analysis or nonparametric analysis revealed that 24-h systolic BP variability and night- time systolic BP variability of the DN group were significantly higher than those of the NDN group [(12.23±3.66) vs. (10.74±3.83) mmHg, P〈0.05; (11.23±4.82) vs. (9.48±3.69) mmHg, P〈0.05]. Then the patients of the DN group were divided into two groups according to glycated hemoglobin (HbAlc) level: Group A (HbA1c〈7%) and Group B (HbA1c〉7%), and the t-test showed that patients in Group B had larger 24-h diastolic, daytime diastolic, and nighttime systolic/diastolic BP variability compared with Group A. In the DN group, partial correlation analysis revealed that HbAlc exhibited a strong association with 24-h diastolic, daytime diastolic, nighttime systolic and diastolic BP vari- ability (P〈0.001, P〈0.001, P〈0.05, and P〈0.001, respectively). Taken together, larger short-term BP variability was detected in hypertensive type 2 diabetic patients with overt nephropathy and renal insufficiency. It may imply that the optimal BP variability level could benefit from a better glycaemic control.展开更多
A coupled earth system model(ESM) has been developed at the Nanjing University of Information Science and Technology(NUIST) by using version 5.3 of the European Centre Hamburg Model(ECHAM), version 3.4 of the Nu...A coupled earth system model(ESM) has been developed at the Nanjing University of Information Science and Technology(NUIST) by using version 5.3 of the European Centre Hamburg Model(ECHAM), version 3.4 of the Nucleus for European Modelling of the Ocean(NEMO), and version 4.1 of the Los Alamos sea ice model(CICE). The model is referred to as NUIST ESM1(NESM1). Comprehensive and quantitative metrics are used to assess the model's major modes of climate variability most relevant to subseasonal-to-interannual climate prediction. The model's assessment is placed in a multi-model framework. The model yields a realistic annual mean and annual cycle of equatorial SST, and a reasonably realistic precipitation climatology, but has difficulty in capturing the spring–fall asymmetry and monsoon precipitation domains. The ENSO mode is reproduced well with respect to its spatial structure, power spectrum, phase locking to the annual cycle, and spatial structures of the central Pacific(CP)-ENSO and eastern Pacific(EP)-ENSO; however, the equatorial SST variability,biennial component of ENSO, and the amplitude of CP-ENSO are overestimated. The model captures realistic intraseasonal variability patterns, the vertical-zonal structures of the first two leading predictable modes of Madden–Julian Oscillation(MJO), and its eastward propagation; but the simulated MJO speed is significantly slower than observed. Compared with the T42 version, the high resolution version(T159) demonstrates improved simulation with respect to the climatology, interannual variance, monsoon–ENSO lead–lag correlation, spatial structures of the leading mode of the Asian–Australian monsoon rainfall variability, and the eastward propagation of the MJO.展开更多
A statistical downscaling approach was developed to improve seasonal-to-interannual prediction of summer rainfall over North China by considering the effect of decadal variability based on observational datasets and d...A statistical downscaling approach was developed to improve seasonal-to-interannual prediction of summer rainfall over North China by considering the effect of decadal variability based on observational datasets and dynamical model outputs.Both predictands and predictors were first decomposed into interannual and decadal components.Two predictive equations were then built separately for the two distinct timescales by using multivariate linear regressions based on independent sample validation.For the interannual timescale,850-hPa meridional wind and 500-hPa geopotential heights from multiple dynamical models' hindcasts and SSTs from observational datasets were used to construct predictors.For the decadal timescale,two well-known basin-scale SST decadal oscillation (the Atlantic Multidecadal Oscillation and the Pacific Decadal Oscillation) indices were used as predictors.Then,the downscaled predictands were combined to represent the predicted/hindcasted total rainfall.The prediction was compared with the models' raw hindcasts and those from a similar approach but without timescale decomposition.In comparison to hindcasts from individual models or their multi-model ensemble mean,the skill of the present scheme was found to be significantly higher,with anomaly correlation coefficients increasing from nearly neutral to over 0.4 and with RMSE decreasing by up to 0.6 mm d-1.The improvements were also seen in the station-based temporal correlation of the predictions with observed rainfall,with the coefficients ranging from-0.1 to 0.87,obviously higher than the models' raw hindcasted rainfall results.Thus,the present approach exhibits a great advantage and may be appropriate for use in operational predictions.展开更多
The Boreal forest is a terrestrial ecosystem highly vulnerable to the impacts of short-term climate and weather variabilities. Detecting abrupt, rapid climate-induced changes in fire weather and related changes in fir...The Boreal forest is a terrestrial ecosystem highly vulnerable to the impacts of short-term climate and weather variabilities. Detecting abrupt, rapid climate-induced changes in fire weather and related changes in fire seasonality can provide important insights to assessing impacts of climate change on forestry. This paper, taking the Sakha Republic of Russia as study area, aims to suggest an approach for detecting signals indicating climate-induced changes in fire weather to express recent fire weather variability by using short-term ranks of major meteorological parameters such as air temperature and atmospheric precipitation. Climate data from the “Global Summary of the Day Product” of NOAA (the United States National Oceanic and Atmospheric Administration) for 1996 to 2018 were used to investigate meteorological parameters that drive fire activity. The detection of the climate change signals is made through a 4-step analysis. First, we used descriptive statistics to grasp monthly, annual, seasonal and peak fire period characteristics of fire weather. Then we computed historical normals for WMO reference period, 1961-1990, and the most recent 30-year period for comparison with the current means. The variability of fire weather is analyzed using standard deviation, coefficient of variation, percentage departures from historical normals, percentage departures from the mean, and precipitation concentration index. Inconsistency and abrupt changes in the evolution of fire weather are assessed using homogeneity analysis whilst a Mann-Kendall test is used to detect significant trends in the time series. The results indicate a significant increase of temperature during spring and fall months, which extends the fire season and potentially contributes to increase of burned areas. We again detected a significant rainfall shortage in September which extended the fire season. Furthermore, this study suggests a new approach in statistical methods appropriate for the detection of climate change signals on fire weather variability using short-term climate ranks and evaluation of its impact on fire seasonality and activity.展开更多
Plants play an essential role in matter and energy transformations and are key messengers in the carbon and energy cycle. Net primary productivity (NPP) reflects the capability of plants to transform solar energy into...Plants play an essential role in matter and energy transformations and are key messengers in the carbon and energy cycle. Net primary productivity (NPP) reflects the capability of plants to transform solar energy into photosynthesis. It is very sensible for factors affecting on vegetation variability such as climate, soils, plant characteristics and human activities. So, it can be used as an indicator of actual and potential trend of vegetation. In this study we used the actual NPP which was derived from MODIS to assess the response of NPP to climate variables in Gadarif State, from 2000 to 2010. The correlations between NPP and climate variables (temperature and precipitation) are calculated using Pearson’s Correlation Coefficient and ordinary least squares regression. The main results show the following 1) the correlation Coefficient between NPP and mean annual temperature is Somewhat negative for Feshaga, Rahd, Gadarif and Galabat areas and weakly negative in Faw area;2) the correlation Coefficient between NPP and annual total precipitation is weakly negative in Faw, Rahd and Galabat areas and somewhat negative in Galabat and Rahd areas. This study demonstrated that the correlation analysis between NPP and climate variables (precipitation and temperature) gives reliably result of NPP responses to climate variables that is clearly in a very large scale of study area.展开更多
An internal state variable(ISV)model was established according to the experimental results of hot plane strain compression(PSC)to predict the microstructure evolution during hot spinning of ZK61 alloy.The effects of t...An internal state variable(ISV)model was established according to the experimental results of hot plane strain compression(PSC)to predict the microstructure evolution during hot spinning of ZK61 alloy.The effects of the internal variables were considered in this ISV model,and the parameters were optimized by genetic algorithm.After validation,the ISV model was used to simulate the evolution of grain size(GS)and dynamic recrystallization(DRX)fraction during hot spinning via Abaqus and its subroutine Vumat.By comparing the simulated results with the experimental results,the application of the ISV model was proven to be reliable.Meanwhile,the strength of the thin-walled spun ZK61 tube increased from 303 to 334 MPa due to grain refinement by DRX and texture strengthening.Besides,some ultrafine grains(0.5μm)that played an important role in mechanical properties were formed due to the proliferation,movement,and entanglement of dislocations during the spinning process.展开更多
In order to solve the problem of the variable coefficient ordinary differen-tial equation on the bounded domain,the Lagrange interpolation method is used to approximate the exact solution of the equation,and the error...In order to solve the problem of the variable coefficient ordinary differen-tial equation on the bounded domain,the Lagrange interpolation method is used to approximate the exact solution of the equation,and the error between the numerical solution and the exact solution is obtained,and then compared with the error formed by the difference method,it is concluded that the Lagrange interpolation method is more effective in solving the variable coefficient ordinary differential equation.展开更多
As a crucial component of the Earth’s climate system,Antarctic sea ice has demonstrated significant variability over the satellite era.Here,we identify a remarkable decadal transition in the total Antarctic Sea Ice E...As a crucial component of the Earth’s climate system,Antarctic sea ice has demonstrated significant variability over the satellite era.Here,we identify a remarkable decadal transition in the total Antarctic Sea Ice Extent(SIE).The stage from 1979 to 2006 is characterized by high-frequency(i.e.,seasonal to interannual)temporal variability in SIE and zonal asymmetry in Sea Ice Concentration(SIC),which is primarily under the control of the Amundsen Sea Low(ASL).After 2007,however,sea ice changes exhibit a more spatially homogeneous pattern in SIC and a more temporally long-lasting mode in SIE.Further analysis reveals that sea ice-ocean interaction plays a major role in the low-frequency(i.e.,multiannual)variability of Antarctic sea ice from 2007−22.The related physical process is inferred to manifest as a strong coupling between the surface and the subsurface ocean layers,involving enhanced vertical convection and the downward delivery of the surface anomalies related to ice melting and freezing processes,thus maintaining the SIE anomalies for a longer time.Furthermore,this process mainly occurs in the Amundsen-Bellingshausen Sea(ABS)sector,and the weakened subsurface ocean stratification is the key factor triggering the coupling process in this region.We find that the Circumpolar Deep Water(CDW)over the ABS sector continued to shoal before 2007 and remained stable thereafter.It is speculated that the shoaling of the CDW may be a possible driver leading to the weakening of the subsurface stratification.展开更多
El Niño-Southern Oscillation(ENSO)is a major driver of climate change in middle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air interaction.Both the ENSO modulation an...El Niño-Southern Oscillation(ENSO)is a major driver of climate change in middle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air interaction.Both the ENSO modulation and carbon flux variability are projected to increase in the future,but their connection still needs further investigation.To investigate the impact of future ENSO modulation on carbon flux variability,this study used 10 CMIP6 earth system models to analyze ENSO modulation and carbon flux variability in middle and low latitudes,and their relationship,under different scenarios simulated by CMIP6 models.The results show a high consistency in the simulations,with both ENSO modulation and carbon flux variability showing an increasing trend in the future.The higher the emissions scenario,especially SSP5-8.5 compared to SSP2-4.5,the greater the increase in variability.Carbon flux variability in the middle and low latitudes under SSP2-4.5 increases by 30.9%compared to historical levels during 1951-2000,while under SSP5-8.5 it increases by 58.2%.Further analysis suggests that ENSO influences mid-and low-latitude carbon flux variability primarily through temperature.This occurrence may potentially be attributed to the increased responsiveness of gross primary productivity towards regional temperature fluctuations,combined with the intensified influence of ENSO on land surface temperatures.展开更多
Large-scale Language Models(LLMs)have achieved significant breakthroughs in Natural Language Processing(NLP),driven by the pre-training and fine-tuning paradigm.While this approach allows models to specialize in speci...Large-scale Language Models(LLMs)have achieved significant breakthroughs in Natural Language Processing(NLP),driven by the pre-training and fine-tuning paradigm.While this approach allows models to specialize in specific tasks with reduced training costs,the substantial memory requirements during fine-tuning present a barrier to broader deployment.Parameter-Efficient Fine-Tuning(PEFT)techniques,such as Low-Rank Adaptation(LoRA),and parameter quantization methods have emerged as solutions to address these challenges by optimizing memory usage and computational efficiency.Among these,QLoRA,which combines PEFT and quantization,has demonstrated notable success in reducing memory footprints during fine-tuning,prompting the development of various QLoRA variants.Despite these advancements,the quantitative impact of key variables on the fine-tuning performance of quantized LLMs remains underexplored.This study presents a comprehensive analysis of these key variables,focusing on their influence across different layer types and depths within LLM architectures.Our investigation uncovers several critical findings:(1)Larger layers,such as MLP layers,can maintain performance despite reductions in adapter rank,while smaller layers,like self-attention layers,aremore sensitive to such changes;(2)The effectiveness of balancing factors depends more on specific values rather than layer type or depth;(3)In quantization-aware fine-tuning,larger layers can effectively utilize smaller adapters,whereas smaller layers struggle to do so.These insights suggest that layer type is a more significant determinant of fine-tuning success than layer depth when optimizing quantized LLMs.Moreover,for the same discount of trainable parameters,reducing the trainable parameters in a larger layer is more effective in preserving fine-tuning accuracy than in a smaller one.This study provides valuable guidance for more efficient fine-tuning strategies and opens avenues for further research into optimizing LLM fine-tuning in resource-constrained environments.展开更多
During the boreal summer,intraseasonal oscillations exhibit significant interannual variations in intensity over two key regions:the central-western equatorial Pacific(5°S-5°N,150°E-150°W)and the s...During the boreal summer,intraseasonal oscillations exhibit significant interannual variations in intensity over two key regions:the central-western equatorial Pacific(5°S-5°N,150°E-150°W)and the subtropical Northwestern Pacific(10°-20°N,130°E-175°W).The former is well-documented and considered to be influenced by the ENSO,while the latter has received comparatively less attention and is likely influenced by the Pacific Meridional Mode(PMM),as suggested by partial correlation analysis results.To elucidate the physical processes responsible for the enhanced(weakened)intraseasonal convection over the subtropical northwestern Pacific during warm(cold)PMM years,the authors employed a moisture budget analysis.The findings reveal that during warm PMM years,there is an increase in summer-mean moisture over the subtropical northwestern Pacific.This increase interacts with intensified vertical motion perturbations in the region,leading to greater vertical moisture advection in the lower troposphere and consequently resulting in convective instability.Such a process is pivotal in amplifying intraseasonal convection anomalies.The observational findings were further verified by model experiments forced by PMM-like sea surface temperature patterns.展开更多
Load forecasting is of great significance to the development of new power systems.With the advancement of smart grids,the integration and distribution of distributed renewable energy sources and power electronics devi...Load forecasting is of great significance to the development of new power systems.With the advancement of smart grids,the integration and distribution of distributed renewable energy sources and power electronics devices have made power load data increasingly complex and volatile.This places higher demands on the prediction and analysis of power loads.In order to improve the prediction accuracy of short-term power load,a CNN-BiLSTMTPA short-term power prediction model based on the Improved Whale Optimization Algorithm(IWOA)with mixed strategies was proposed.Firstly,the model combined the Convolutional Neural Network(CNN)with the Bidirectional Long Short-Term Memory Network(BiLSTM)to fully extract the spatio-temporal characteristics of the load data itself.Then,the Temporal Pattern Attention(TPA)mechanism was introduced into the CNN-BiLSTM model to automatically assign corresponding weights to the hidden states of the BiLSTM.This allowed the model to differentiate the importance of load sequences at different time intervals.At the same time,in order to solve the problem of the difficulties of selecting the parameters of the temporal model,and the poor global search ability of the whale algorithm,which is easy to fall into the local optimization,the whale algorithm(IWOA)was optimized by using the hybrid strategy of Tent chaos mapping and Levy flight strategy,so as to better search the parameters of the model.In this experiment,the real load data of a region in Zhejiang was taken as an example to analyze,and the prediction accuracy(R2)of the proposed method reached 98.83%.Compared with the prediction models such as BP,WOA-CNN-BiLSTM,SSA-CNN-BiLSTM,CNN-BiGRU-Attention,etc.,the experimental results showed that the model proposed in this study has a higher prediction accuracy.展开更多
Maize is an important source of calories and protein in human lives in many countries of the world and is the main staple food in Africa, particularly in eastern Africa. In the Sudan, the low yield of maize was mainly...Maize is an important source of calories and protein in human lives in many countries of the world and is the main staple food in Africa, particularly in eastern Africa. In the Sudan, the low yield of maize was mainly due to the use of low yielding landraces. It is necessary to carry out breeding programs that deal with the production of high yielding, adaptable new varieties. Therefore, this study aimed to estimate genetic variability, heritability, genotypic performance and interrelationships among the traits. Ten maize genotypes evaluated at White Nile Research Station Farm, Kosti, of the Agricultural Research Corporation (ARC), Wad Medani Sudan were planted in a randomized complete block design with three replications during the two seasons of 2021 and 2022. Most evaluated genotypes exhibited a wide and significant variation in the 11 measured traits. Genotypic coefficient of variation and genetic advance were recorded for days to 50% tasseling, ear diameter (cm), number of grains per row and grain yield (t/ha) in both seasons. High heritability and genetic advance were recorded for grain yield, ear length, ear height, plant height, number of rows per ear, ear weight, days to 50% tasseling, 100-grain weight and days to 50% silking. Moreover, there was a highly significant and positive correlation of grain yield with number of rows per ear (r = 0.479), ear length (r = 0.381), 100-grain weight (r = 0.344) and days to 50% tasseling (r = 0.214). The highest yielding five genotypes across the seasons were TZCOM1/ZDPSYN (4.2 t/ha), EEPVAH-3 (4.2 t/ha), F2TWLY131228 (4.1 t/ha), PVA SYN6F2 (3.9 t/ha) and EEPVAH-9 (3.8 t/ha) these were needed to check the adaptability, stability and to test major maize growing areas to make sound recommendations for release.展开更多
We consider a single server constant retrial queue,in which a state-dependent service policy is used to control the service rate.Customer arrival follows Poisson process,while service time and retrial time are exponen...We consider a single server constant retrial queue,in which a state-dependent service policy is used to control the service rate.Customer arrival follows Poisson process,while service time and retrial time are exponential distributions.Whenever the server is available,it admits the retrial customers into service based on a first-come first-served rule.The service rate adjusts in real-time based on the retrial queue length.An iterative algorithm is proposed to numerically solve the personal optimal problem in the fully observable scenario.Furthermore,we investigate the impact of parameters on the social optimal threshold.The effectiveness of the results is illustrated by two examples.展开更多
The Indonesian Throughflow(ITF)plays important roles in global ocean circulation and climate systems.Previous studies suggested the ITF interannual variability is driven by both the El Niño-Southern Oscillation(E...The Indonesian Throughflow(ITF)plays important roles in global ocean circulation and climate systems.Previous studies suggested the ITF interannual variability is driven by both the El Niño-Southern Oscillation(ENSO)and the Indian Ocean Dipole(IOD)events.The detailed processes of ENSO and/or IOD induced anomalies impacting on the ITF,however,are still not clear.In this study,this issue is investigated through causal relation,statistical,and dynamical analyses based on satellite observation.The results show that the driven mechanisms of ENSO on the ITF include two aspects.Firstly,the ENSO related wind field anomalies driven anomalous cyclonic ocean circulation in the western Pacific,and off equatorial upwelling Rossby waves propagating westward to arrive at the western boundary of the Pacific,both tend to induce negative sea surface height anomalies(SSHA)in the western Pacific,favoring ITF reduction since the develop of the El Niño through the following year.Secondly,the ENSO events modulate equatorial Indian Ocean zonal winds through Walker Circulation,which in turn trigger eastward propagating upwelling Kelvin waves and westward propagating downwelling Rossby waves.The Rossby waves are reflected into downwelling Kelvin waves,which then propagate eastward along the equator and the Sumatra-Java coast in the Indian Ocean.As a result,the wave dynamics tend to generate negative(positive)SSHA in the eastern Indian Ocean,and thus enhance(reduce)the ITF transport with time lag of 0-6 months(9-12 months),respectively.Under the IOD condition,the wave dynamics also tend to enhance the ITF in the positive IOD year,and reduce the ITF in the following year.展开更多
Varietal deficiencies of upland rice lead to a low paddy grain yield. The aim of this study was to mutagenesis upland rice varieties to improve their agronomic performance. Seeds of varieties FKR45N and FKR47N were th...Varietal deficiencies of upland rice lead to a low paddy grain yield. The aim of this study was to mutagenesis upland rice varieties to improve their agronomic performance. Seeds of varieties FKR45N and FKR47N were therefore irradiated with doses 300, 350 and 400 Gy. The irradiated seeds were sown and the panicles of the M1 plants were individually harvested, and then were advanced to M4 using the “one panicle - one progeny” method. The agronomic performance of M4 lines was compared to that of their parent. The gamma ray mutagenesis has induced significant variability in five yield components, i.e., plant height, main panicle length, total numbers of tillers and productive tillers and paddy grain yield between mutant lines. The highest variabilities were shown for the total number of tillers and the number of productive tillers as well as FKR45N (CV% = 40 % and 36%) and FKR47N (CV% = 31% and 30%) mutant lines. Principal component analysis led to rank the mutant lines from each variety in three clusters. The Pearson correlation showed that the paddy grain yield was significantly and positively correlated with the number of productive tillers (r = 0.61) and plant height (r = 0.66) for FKR47N mutant lines, and these correlation coefficients were r = 0.52 and r = 0.51 for FKR45N mutant lines, respectively. Gamma-ray irradiation also induced an earliness of 50% flowering of 62 days after sowing (DAS) in two FKR45N mutant lines and 67 DAS in one of KR47N mutant lines. The paddy grain yield was improved by 120% and 20% in two FKR45N and FKR47N mutant lines, respectively. A dwarf FKR45N mutant line with an early flowering of 67 DAS and a paddy grain yield (2.34 t ha−1) was generated. These results suggested that any positive increase in the six quantitative traits will increase the paddy grain yield.展开更多
Fiber-reinforced composites are an ideal material for the lightweight design of aerospace structures. Especially in recent years, with the rapid development of composite additive manufacturing technology, the design o...Fiber-reinforced composites are an ideal material for the lightweight design of aerospace structures. Especially in recent years, with the rapid development of composite additive manufacturing technology, the design optimization of variable stiffness of fiber-reinforced composite laminates has attracted widespread attention from scholars and industry. In these aerospace composite structures, numerous cutout panels and shells serve as access points for maintaining electrical, fuel, and hydraulic systems. The traditional fiber-reinforced composite laminate subtractive drilling manufacturing inevitably faces the problems of interlayer delamination, fiber fracture, and burr of the laminate. Continuous fiber additive manufacturing technology offers the potential for integrated design optimization and manufacturing with high structural performance. Considering the integration of design and manufacturability in continuous fiber additive manufacturing, the paper proposes linear and nonlinear filtering strategies based on the Normal Distribution Fiber Optimization (NDFO) material interpolation scheme to overcome the challenge of discrete fiber optimization results, which are difficult to apply directly to continuous fiber additive manufacturing. With minimizing structural compliance as the objective function, the proposed approach provides a strategy to achieve continuity of discrete fiber paths in the variable stiffness design optimization of composite laminates with regular and irregular holes. In the variable stiffness design optimization model, the number of candidate fiber laying angles in the NDFO material interpolation scheme is considered as design variable. The sensitivity information of structural compliance with respect to the number of candidate fiber laying angles is obtained using the analytical sensitivity analysis method. Based on the proposed variable stiffness design optimization method for complex perforated composite laminates, the numerical examples consider the variable stiffness design optimization of typical non-perforated and perforated composite laminates with circular, square, and irregular holes, and systematically discuss the number of candidate discrete fiber laying angles, discrete fiber continuous filtering strategies, and filter radius on structural compliance, continuity, and manufacturability. The optimized discrete fiber angles of variable stiffness laminates are converted into continuous fiber laying paths using a streamlined process for continuous fiber additive manufacturing. Meanwhile, the optimized non-perforated and perforated MBB beams after discrete fiber continuous treatment, are manufactured using continuous fiber co-extrusion additive manufacturing technology to verify the effectiveness of the variable stiffness fiber optimization framework proposed in this paper.展开更多
BACKGROUND Surgery is the first choice of treatment for patients with colorectal cancer.Traditional open surgery imparts great damage to the body of the patient and can easily cause adverse stress reactions.With the c...BACKGROUND Surgery is the first choice of treatment for patients with colorectal cancer.Traditional open surgery imparts great damage to the body of the patient and can easily cause adverse stress reactions.With the continuous development of medical technology,laparoscopic minimally invasive surgery has shown great advantages for the treatment of patients with celiac disease.AIM To investigate the short-term efficacy of laparoscopic radical surgery and traditional laparotomy for the treatment of colorectal cancer,and the differences in the risk analysis of unplanned reoperation after operation.METHODS As the research subjects,this study selected 100 patients with colorectal cancer who received surgical treatment at the Yulin First Hospital from January 2018 to January 2022.Among them,50 patients who underwent laparoscopic radical resection were selected as the research group and 50 patients who underwent traditional laparotomy were selected as the control group.Data pertaining to clinical indexes,gastrointestinal hormones,nutrition indexes,the levels of inflammatory factors,quality of life,Visual Analog Scale score,and the postoperative complications of the two groups of patients before and after treatment were collected,and the therapeutic effects in the two groups were analyzed and compared.RESULTS Compared with the control group,perioperative bleeding,peristalsis recovery time,and hospital stays were significantly shorter in the research group.After surgery,the levels of gastrin(GAS)and motilin(MTL)were decreased in both groups,and the fluctuation range of GAS and MTL observed in the research group was significantly lower than that recorded in the control group.The hemoglobin(Hb)levels increased after surgery,and the level of Hb in the research group was significantly higher compared with the control group.After the operation,the expression levels of tumor necrosis factor-α,interleukin-6,and C-reactive protein and the total incidence of complications were significantly lower in the research group compared with the control group.One year after the operation,the quality of life of the two groups was greatly improved,with the quality of life in the research group being significantly better.CONCLUSION Laparoscopy was effective for colorectal surgery by reducing the occurrence of complications and inflammatory stress reaction;moreover,the quality of life of patients was significantly improved,which warrants further promotion.展开更多
The complete convergence for weighted sums of sequences of independent,identically distributed random variables under sublinear expectation space is studied.By moment inequality and truncation methods,we establish the...The complete convergence for weighted sums of sequences of independent,identically distributed random variables under sublinear expectation space is studied.By moment inequality and truncation methods,we establish the equivalent conditions of complete convergence for weighted sums of sequences of independent,identically distributed random variables under sublinear expectation space.The results complement the corresponding results in probability space to those for sequences of independent,identically distributed random variables under sublinear expectation space.展开更多
基金Supported by Ministry of Health of the Russian Federation titled Development of a Hardware-Software Complex for the Non-Invasive Monitoring and Prediction of Circulatory Decompensation in Patients with Chronic Heart Failure,No.125030703255-7.
文摘BACKGROUND The six-minute walk test(6MWT)allows to determine,in addition to the main parameters,the time of heart rate recovery(THRR),cardiac function,adaptation index(AI),which characterize the compensatory reserve of patients with chronic heart failure(CHF).At the same time,the significance of these parameters in patients taking beta-blockers for CHF is insufficiently studied,taking into account the negative chronotropic effect of drugs.In this regard,it is relevant to identify factors that can characterize the compensatory capabilities of a patient with CHF during 6MWT,not related to the calculation of heart rate.AIM To identify hemodynamic indicators of the adaptive capabilities of patients with CHF during paired 6MWT depending on their intake of beta-blockers.METHODS Seventy-four patients with compensated CHF due to coronary heart disease and/or hypertension formed the main group,comprising 46 individuals who were taking beta-blockers,and a comparison group comprising 28 individuals who had not been taking beta-blockers for at least one month before 6MWT.All participants underwent Doppler echocardiography(DECG),paired 6MWT,with assessment of hemodynamic parameters before and after both the first and second test.AI,THRR,blood pressure variability(BPV)were calculated.Multivariate,correlation analyses,univariate analysis of variance were used.RESULTS There were no significant associations between adaptation characteristics and DECG parameters or functional class(FC)of CHF in patients of the main group.In the comparison group,the indicators of compensatory reserve were significantly and directly associated with left ventricular ejection fraction(LVEF),and inversely with FC CHF and cardiac cavity size.In both groups,a greater difference in systolic blood pressure between the end of the first and the beginning of the second 6MWT was significantly associated with a higher index of right ventricular systolic dysfunction(Tricuspid annular plane systolic excursion)and LVEF,as well as a smaller left ventricular size and mass,and a lower pulmonary artery systolic pressure in patients in the main group.CONCLUSION Systolic BPV,measured immediately after 6MWT and 20 minutes after its completion,can indirectly characterize the compensatory reserve in patients with CHF,regardless of their beta-blocker intake.
基金Project (Nos.2011SZ0215 and 2012SZ0027) supported by the Science and Technology Research Projects of Sichuan Province,China
文摘The aim of this study was to understand the characteristics of blood pressure (BP) variability in subjects with diabetic nephropathy (DN), and identify the probable predictors affecting BP variability. Fifty-one chronic kidney disease (CKD)-hypertensive patients without diabetes (NDN group) and sixty type 2 diabetic patients with overt DN (DN group) were enrolled in this study. The values of short-term BP variability were obtained from 24 h ambulatory BP monitoring (ABPM). Variance analysis or nonparametric analysis revealed that 24-h systolic BP variability and night- time systolic BP variability of the DN group were significantly higher than those of the NDN group [(12.23±3.66) vs. (10.74±3.83) mmHg, P〈0.05; (11.23±4.82) vs. (9.48±3.69) mmHg, P〈0.05]. Then the patients of the DN group were divided into two groups according to glycated hemoglobin (HbAlc) level: Group A (HbA1c〈7%) and Group B (HbA1c〉7%), and the t-test showed that patients in Group B had larger 24-h diastolic, daytime diastolic, and nighttime systolic/diastolic BP variability compared with Group A. In the DN group, partial correlation analysis revealed that HbAlc exhibited a strong association with 24-h diastolic, daytime diastolic, nighttime systolic and diastolic BP vari- ability (P〈0.001, P〈0.001, P〈0.05, and P〈0.001, respectively). Taken together, larger short-term BP variability was detected in hypertensive type 2 diabetic patients with overt nephropathy and renal insufficiency. It may imply that the optimal BP variability level could benefit from a better glycaemic control.
基金supported by the Research Innovation Program for college graduates of Jiangsu Province (CXLX13 487)
文摘A coupled earth system model(ESM) has been developed at the Nanjing University of Information Science and Technology(NUIST) by using version 5.3 of the European Centre Hamburg Model(ECHAM), version 3.4 of the Nucleus for European Modelling of the Ocean(NEMO), and version 4.1 of the Los Alamos sea ice model(CICE). The model is referred to as NUIST ESM1(NESM1). Comprehensive and quantitative metrics are used to assess the model's major modes of climate variability most relevant to subseasonal-to-interannual climate prediction. The model's assessment is placed in a multi-model framework. The model yields a realistic annual mean and annual cycle of equatorial SST, and a reasonably realistic precipitation climatology, but has difficulty in capturing the spring–fall asymmetry and monsoon precipitation domains. The ENSO mode is reproduced well with respect to its spatial structure, power spectrum, phase locking to the annual cycle, and spatial structures of the central Pacific(CP)-ENSO and eastern Pacific(EP)-ENSO; however, the equatorial SST variability,biennial component of ENSO, and the amplitude of CP-ENSO are overestimated. The model captures realistic intraseasonal variability patterns, the vertical-zonal structures of the first two leading predictable modes of Madden–Julian Oscillation(MJO), and its eastward propagation; but the simulated MJO speed is significantly slower than observed. Compared with the T42 version, the high resolution version(T159) demonstrates improved simulation with respect to the climatology, interannual variance, monsoon–ENSO lead–lag correlation, spatial structures of the leading mode of the Asian–Australian monsoon rainfall variability, and the eastward propagation of the MJO.
基金supported by the Special Program in the Public Interest of the China Meteorological Administration (Grant No. GYHY201006022)the Strategic Special Projects of the Chinese Academy of Sciences (Grant No. XDA05090000)
文摘A statistical downscaling approach was developed to improve seasonal-to-interannual prediction of summer rainfall over North China by considering the effect of decadal variability based on observational datasets and dynamical model outputs.Both predictands and predictors were first decomposed into interannual and decadal components.Two predictive equations were then built separately for the two distinct timescales by using multivariate linear regressions based on independent sample validation.For the interannual timescale,850-hPa meridional wind and 500-hPa geopotential heights from multiple dynamical models' hindcasts and SSTs from observational datasets were used to construct predictors.For the decadal timescale,two well-known basin-scale SST decadal oscillation (the Atlantic Multidecadal Oscillation and the Pacific Decadal Oscillation) indices were used as predictors.Then,the downscaled predictands were combined to represent the predicted/hindcasted total rainfall.The prediction was compared with the models' raw hindcasts and those from a similar approach but without timescale decomposition.In comparison to hindcasts from individual models or their multi-model ensemble mean,the skill of the present scheme was found to be significantly higher,with anomaly correlation coefficients increasing from nearly neutral to over 0.4 and with RMSE decreasing by up to 0.6 mm d-1.The improvements were also seen in the station-based temporal correlation of the predictions with observed rainfall,with the coefficients ranging from-0.1 to 0.87,obviously higher than the models' raw hindcasted rainfall results.Thus,the present approach exhibits a great advantage and may be appropriate for use in operational predictions.
文摘The Boreal forest is a terrestrial ecosystem highly vulnerable to the impacts of short-term climate and weather variabilities. Detecting abrupt, rapid climate-induced changes in fire weather and related changes in fire seasonality can provide important insights to assessing impacts of climate change on forestry. This paper, taking the Sakha Republic of Russia as study area, aims to suggest an approach for detecting signals indicating climate-induced changes in fire weather to express recent fire weather variability by using short-term ranks of major meteorological parameters such as air temperature and atmospheric precipitation. Climate data from the “Global Summary of the Day Product” of NOAA (the United States National Oceanic and Atmospheric Administration) for 1996 to 2018 were used to investigate meteorological parameters that drive fire activity. The detection of the climate change signals is made through a 4-step analysis. First, we used descriptive statistics to grasp monthly, annual, seasonal and peak fire period characteristics of fire weather. Then we computed historical normals for WMO reference period, 1961-1990, and the most recent 30-year period for comparison with the current means. The variability of fire weather is analyzed using standard deviation, coefficient of variation, percentage departures from historical normals, percentage departures from the mean, and precipitation concentration index. Inconsistency and abrupt changes in the evolution of fire weather are assessed using homogeneity analysis whilst a Mann-Kendall test is used to detect significant trends in the time series. The results indicate a significant increase of temperature during spring and fall months, which extends the fire season and potentially contributes to increase of burned areas. We again detected a significant rainfall shortage in September which extended the fire season. Furthermore, this study suggests a new approach in statistical methods appropriate for the detection of climate change signals on fire weather variability using short-term climate ranks and evaluation of its impact on fire seasonality and activity.
文摘Plants play an essential role in matter and energy transformations and are key messengers in the carbon and energy cycle. Net primary productivity (NPP) reflects the capability of plants to transform solar energy into photosynthesis. It is very sensible for factors affecting on vegetation variability such as climate, soils, plant characteristics and human activities. So, it can be used as an indicator of actual and potential trend of vegetation. In this study we used the actual NPP which was derived from MODIS to assess the response of NPP to climate variables in Gadarif State, from 2000 to 2010. The correlations between NPP and climate variables (temperature and precipitation) are calculated using Pearson’s Correlation Coefficient and ordinary least squares regression. The main results show the following 1) the correlation Coefficient between NPP and mean annual temperature is Somewhat negative for Feshaga, Rahd, Gadarif and Galabat areas and weakly negative in Faw area;2) the correlation Coefficient between NPP and annual total precipitation is weakly negative in Faw, Rahd and Galabat areas and somewhat negative in Galabat and Rahd areas. This study demonstrated that the correlation analysis between NPP and climate variables (precipitation and temperature) gives reliably result of NPP responses to climate variables that is clearly in a very large scale of study area.
基金supported by the National Natural Science Foundation of China(No.51905123)Major Scientific and Technological Innovation Program of Shandong Province,China(Nos.2020CXGC010303,2022ZLGX04)Key R&D Programme of Shandong Province,China(No.2022JMRH0308).
文摘An internal state variable(ISV)model was established according to the experimental results of hot plane strain compression(PSC)to predict the microstructure evolution during hot spinning of ZK61 alloy.The effects of the internal variables were considered in this ISV model,and the parameters were optimized by genetic algorithm.After validation,the ISV model was used to simulate the evolution of grain size(GS)and dynamic recrystallization(DRX)fraction during hot spinning via Abaqus and its subroutine Vumat.By comparing the simulated results with the experimental results,the application of the ISV model was proven to be reliable.Meanwhile,the strength of the thin-walled spun ZK61 tube increased from 303 to 334 MPa due to grain refinement by DRX and texture strengthening.Besides,some ultrafine grains(0.5μm)that played an important role in mechanical properties were formed due to the proliferation,movement,and entanglement of dislocations during the spinning process.
文摘In order to solve the problem of the variable coefficient ordinary differen-tial equation on the bounded domain,the Lagrange interpolation method is used to approximate the exact solution of the equation,and the error between the numerical solution and the exact solution is obtained,and then compared with the error formed by the difference method,it is concluded that the Lagrange interpolation method is more effective in solving the variable coefficient ordinary differential equation.
基金supported by the National Natural Science Foundation China(Grant No.42176222).
文摘As a crucial component of the Earth’s climate system,Antarctic sea ice has demonstrated significant variability over the satellite era.Here,we identify a remarkable decadal transition in the total Antarctic Sea Ice Extent(SIE).The stage from 1979 to 2006 is characterized by high-frequency(i.e.,seasonal to interannual)temporal variability in SIE and zonal asymmetry in Sea Ice Concentration(SIC),which is primarily under the control of the Amundsen Sea Low(ASL).After 2007,however,sea ice changes exhibit a more spatially homogeneous pattern in SIC and a more temporally long-lasting mode in SIE.Further analysis reveals that sea ice-ocean interaction plays a major role in the low-frequency(i.e.,multiannual)variability of Antarctic sea ice from 2007−22.The related physical process is inferred to manifest as a strong coupling between the surface and the subsurface ocean layers,involving enhanced vertical convection and the downward delivery of the surface anomalies related to ice melting and freezing processes,thus maintaining the SIE anomalies for a longer time.Furthermore,this process mainly occurs in the Amundsen-Bellingshausen Sea(ABS)sector,and the weakened subsurface ocean stratification is the key factor triggering the coupling process in this region.We find that the Circumpolar Deep Water(CDW)over the ABS sector continued to shoal before 2007 and remained stable thereafter.It is speculated that the shoaling of the CDW may be a possible driver leading to the weakening of the subsurface stratification.
基金jointly supported by projects of the National Natural Science Foundation of China [grant numbers 42141017 and 41975112]。
文摘El Niño-Southern Oscillation(ENSO)is a major driver of climate change in middle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air interaction.Both the ENSO modulation and carbon flux variability are projected to increase in the future,but their connection still needs further investigation.To investigate the impact of future ENSO modulation on carbon flux variability,this study used 10 CMIP6 earth system models to analyze ENSO modulation and carbon flux variability in middle and low latitudes,and their relationship,under different scenarios simulated by CMIP6 models.The results show a high consistency in the simulations,with both ENSO modulation and carbon flux variability showing an increasing trend in the future.The higher the emissions scenario,especially SSP5-8.5 compared to SSP2-4.5,the greater the increase in variability.Carbon flux variability in the middle and low latitudes under SSP2-4.5 increases by 30.9%compared to historical levels during 1951-2000,while under SSP5-8.5 it increases by 58.2%.Further analysis suggests that ENSO influences mid-and low-latitude carbon flux variability primarily through temperature.This occurrence may potentially be attributed to the increased responsiveness of gross primary productivity towards regional temperature fluctuations,combined with the intensified influence of ENSO on land surface temperatures.
基金supported by the National Key R&D Program of China(No.2021YFB0301200)National Natural Science Foundation of China(No.62025208).
文摘Large-scale Language Models(LLMs)have achieved significant breakthroughs in Natural Language Processing(NLP),driven by the pre-training and fine-tuning paradigm.While this approach allows models to specialize in specific tasks with reduced training costs,the substantial memory requirements during fine-tuning present a barrier to broader deployment.Parameter-Efficient Fine-Tuning(PEFT)techniques,such as Low-Rank Adaptation(LoRA),and parameter quantization methods have emerged as solutions to address these challenges by optimizing memory usage and computational efficiency.Among these,QLoRA,which combines PEFT and quantization,has demonstrated notable success in reducing memory footprints during fine-tuning,prompting the development of various QLoRA variants.Despite these advancements,the quantitative impact of key variables on the fine-tuning performance of quantized LLMs remains underexplored.This study presents a comprehensive analysis of these key variables,focusing on their influence across different layer types and depths within LLM architectures.Our investigation uncovers several critical findings:(1)Larger layers,such as MLP layers,can maintain performance despite reductions in adapter rank,while smaller layers,like self-attention layers,aremore sensitive to such changes;(2)The effectiveness of balancing factors depends more on specific values rather than layer type or depth;(3)In quantization-aware fine-tuning,larger layers can effectively utilize smaller adapters,whereas smaller layers struggle to do so.These insights suggest that layer type is a more significant determinant of fine-tuning success than layer depth when optimizing quantized LLMs.Moreover,for the same discount of trainable parameters,reducing the trainable parameters in a larger layer is more effective in preserving fine-tuning accuracy than in a smaller one.This study provides valuable guidance for more efficient fine-tuning strategies and opens avenues for further research into optimizing LLM fine-tuning in resource-constrained environments.
基金supported by the National Natural Science Foundation of China [grant number 42088101]。
文摘During the boreal summer,intraseasonal oscillations exhibit significant interannual variations in intensity over two key regions:the central-western equatorial Pacific(5°S-5°N,150°E-150°W)and the subtropical Northwestern Pacific(10°-20°N,130°E-175°W).The former is well-documented and considered to be influenced by the ENSO,while the latter has received comparatively less attention and is likely influenced by the Pacific Meridional Mode(PMM),as suggested by partial correlation analysis results.To elucidate the physical processes responsible for the enhanced(weakened)intraseasonal convection over the subtropical northwestern Pacific during warm(cold)PMM years,the authors employed a moisture budget analysis.The findings reveal that during warm PMM years,there is an increase in summer-mean moisture over the subtropical northwestern Pacific.This increase interacts with intensified vertical motion perturbations in the region,leading to greater vertical moisture advection in the lower troposphere and consequently resulting in convective instability.Such a process is pivotal in amplifying intraseasonal convection anomalies.The observational findings were further verified by model experiments forced by PMM-like sea surface temperature patterns.
文摘Load forecasting is of great significance to the development of new power systems.With the advancement of smart grids,the integration and distribution of distributed renewable energy sources and power electronics devices have made power load data increasingly complex and volatile.This places higher demands on the prediction and analysis of power loads.In order to improve the prediction accuracy of short-term power load,a CNN-BiLSTMTPA short-term power prediction model based on the Improved Whale Optimization Algorithm(IWOA)with mixed strategies was proposed.Firstly,the model combined the Convolutional Neural Network(CNN)with the Bidirectional Long Short-Term Memory Network(BiLSTM)to fully extract the spatio-temporal characteristics of the load data itself.Then,the Temporal Pattern Attention(TPA)mechanism was introduced into the CNN-BiLSTM model to automatically assign corresponding weights to the hidden states of the BiLSTM.This allowed the model to differentiate the importance of load sequences at different time intervals.At the same time,in order to solve the problem of the difficulties of selecting the parameters of the temporal model,and the poor global search ability of the whale algorithm,which is easy to fall into the local optimization,the whale algorithm(IWOA)was optimized by using the hybrid strategy of Tent chaos mapping and Levy flight strategy,so as to better search the parameters of the model.In this experiment,the real load data of a region in Zhejiang was taken as an example to analyze,and the prediction accuracy(R2)of the proposed method reached 98.83%.Compared with the prediction models such as BP,WOA-CNN-BiLSTM,SSA-CNN-BiLSTM,CNN-BiGRU-Attention,etc.,the experimental results showed that the model proposed in this study has a higher prediction accuracy.
文摘Maize is an important source of calories and protein in human lives in many countries of the world and is the main staple food in Africa, particularly in eastern Africa. In the Sudan, the low yield of maize was mainly due to the use of low yielding landraces. It is necessary to carry out breeding programs that deal with the production of high yielding, adaptable new varieties. Therefore, this study aimed to estimate genetic variability, heritability, genotypic performance and interrelationships among the traits. Ten maize genotypes evaluated at White Nile Research Station Farm, Kosti, of the Agricultural Research Corporation (ARC), Wad Medani Sudan were planted in a randomized complete block design with three replications during the two seasons of 2021 and 2022. Most evaluated genotypes exhibited a wide and significant variation in the 11 measured traits. Genotypic coefficient of variation and genetic advance were recorded for days to 50% tasseling, ear diameter (cm), number of grains per row and grain yield (t/ha) in both seasons. High heritability and genetic advance were recorded for grain yield, ear length, ear height, plant height, number of rows per ear, ear weight, days to 50% tasseling, 100-grain weight and days to 50% silking. Moreover, there was a highly significant and positive correlation of grain yield with number of rows per ear (r = 0.479), ear length (r = 0.381), 100-grain weight (r = 0.344) and days to 50% tasseling (r = 0.214). The highest yielding five genotypes across the seasons were TZCOM1/ZDPSYN (4.2 t/ha), EEPVAH-3 (4.2 t/ha), F2TWLY131228 (4.1 t/ha), PVA SYN6F2 (3.9 t/ha) and EEPVAH-9 (3.8 t/ha) these were needed to check the adaptability, stability and to test major maize growing areas to make sound recommendations for release.
基金supported by the National Natural Science Foundation of China(Grant No.11971486)。
文摘We consider a single server constant retrial queue,in which a state-dependent service policy is used to control the service rate.Customer arrival follows Poisson process,while service time and retrial time are exponential distributions.Whenever the server is available,it admits the retrial customers into service based on a first-come first-served rule.The service rate adjusts in real-time based on the retrial queue length.An iterative algorithm is proposed to numerically solve the personal optimal problem in the fully observable scenario.Furthermore,we investigate the impact of parameters on the social optimal threshold.The effectiveness of the results is illustrated by two examples.
基金The Fund of Laoshan Laboratory under contract No.LSKJ202202700the Basic Scientific Fund for National Public Research Institutes of China under contract No.2024Q02+1 种基金the National Natural Science Foundation of China under contract Nos 42076023 and 42430402the Global Change and Air-Sea InteractionⅡProject under contract No.GASI-01-ATP-STwin.
文摘The Indonesian Throughflow(ITF)plays important roles in global ocean circulation and climate systems.Previous studies suggested the ITF interannual variability is driven by both the El Niño-Southern Oscillation(ENSO)and the Indian Ocean Dipole(IOD)events.The detailed processes of ENSO and/or IOD induced anomalies impacting on the ITF,however,are still not clear.In this study,this issue is investigated through causal relation,statistical,and dynamical analyses based on satellite observation.The results show that the driven mechanisms of ENSO on the ITF include two aspects.Firstly,the ENSO related wind field anomalies driven anomalous cyclonic ocean circulation in the western Pacific,and off equatorial upwelling Rossby waves propagating westward to arrive at the western boundary of the Pacific,both tend to induce negative sea surface height anomalies(SSHA)in the western Pacific,favoring ITF reduction since the develop of the El Niño through the following year.Secondly,the ENSO events modulate equatorial Indian Ocean zonal winds through Walker Circulation,which in turn trigger eastward propagating upwelling Kelvin waves and westward propagating downwelling Rossby waves.The Rossby waves are reflected into downwelling Kelvin waves,which then propagate eastward along the equator and the Sumatra-Java coast in the Indian Ocean.As a result,the wave dynamics tend to generate negative(positive)SSHA in the eastern Indian Ocean,and thus enhance(reduce)the ITF transport with time lag of 0-6 months(9-12 months),respectively.Under the IOD condition,the wave dynamics also tend to enhance the ITF in the positive IOD year,and reduce the ITF in the following year.
文摘Varietal deficiencies of upland rice lead to a low paddy grain yield. The aim of this study was to mutagenesis upland rice varieties to improve their agronomic performance. Seeds of varieties FKR45N and FKR47N were therefore irradiated with doses 300, 350 and 400 Gy. The irradiated seeds were sown and the panicles of the M1 plants were individually harvested, and then were advanced to M4 using the “one panicle - one progeny” method. The agronomic performance of M4 lines was compared to that of their parent. The gamma ray mutagenesis has induced significant variability in five yield components, i.e., plant height, main panicle length, total numbers of tillers and productive tillers and paddy grain yield between mutant lines. The highest variabilities were shown for the total number of tillers and the number of productive tillers as well as FKR45N (CV% = 40 % and 36%) and FKR47N (CV% = 31% and 30%) mutant lines. Principal component analysis led to rank the mutant lines from each variety in three clusters. The Pearson correlation showed that the paddy grain yield was significantly and positively correlated with the number of productive tillers (r = 0.61) and plant height (r = 0.66) for FKR47N mutant lines, and these correlation coefficients were r = 0.52 and r = 0.51 for FKR45N mutant lines, respectively. Gamma-ray irradiation also induced an earliness of 50% flowering of 62 days after sowing (DAS) in two FKR45N mutant lines and 67 DAS in one of KR47N mutant lines. The paddy grain yield was improved by 120% and 20% in two FKR45N and FKR47N mutant lines, respectively. A dwarf FKR45N mutant line with an early flowering of 67 DAS and a paddy grain yield (2.34 t ha−1) was generated. These results suggested that any positive increase in the six quantitative traits will increase the paddy grain yield.
基金supports for this research were provided by the National Natural Science Foundation of China(No.12272301,12002278,U1906233)the Guangdong Basic and Applied Basic Research Foundation,China(Nos.2023A1515011970,2024A1515010256)+1 种基金the Dalian City Supports Innovation and Entrepreneurship Projects for High-Level Talents,China(2021RD16)the Key R&D Project of CSCEC,China(No.CSCEC-2020-Z-4).
文摘Fiber-reinforced composites are an ideal material for the lightweight design of aerospace structures. Especially in recent years, with the rapid development of composite additive manufacturing technology, the design optimization of variable stiffness of fiber-reinforced composite laminates has attracted widespread attention from scholars and industry. In these aerospace composite structures, numerous cutout panels and shells serve as access points for maintaining electrical, fuel, and hydraulic systems. The traditional fiber-reinforced composite laminate subtractive drilling manufacturing inevitably faces the problems of interlayer delamination, fiber fracture, and burr of the laminate. Continuous fiber additive manufacturing technology offers the potential for integrated design optimization and manufacturing with high structural performance. Considering the integration of design and manufacturability in continuous fiber additive manufacturing, the paper proposes linear and nonlinear filtering strategies based on the Normal Distribution Fiber Optimization (NDFO) material interpolation scheme to overcome the challenge of discrete fiber optimization results, which are difficult to apply directly to continuous fiber additive manufacturing. With minimizing structural compliance as the objective function, the proposed approach provides a strategy to achieve continuity of discrete fiber paths in the variable stiffness design optimization of composite laminates with regular and irregular holes. In the variable stiffness design optimization model, the number of candidate fiber laying angles in the NDFO material interpolation scheme is considered as design variable. The sensitivity information of structural compliance with respect to the number of candidate fiber laying angles is obtained using the analytical sensitivity analysis method. Based on the proposed variable stiffness design optimization method for complex perforated composite laminates, the numerical examples consider the variable stiffness design optimization of typical non-perforated and perforated composite laminates with circular, square, and irregular holes, and systematically discuss the number of candidate discrete fiber laying angles, discrete fiber continuous filtering strategies, and filter radius on structural compliance, continuity, and manufacturability. The optimized discrete fiber angles of variable stiffness laminates are converted into continuous fiber laying paths using a streamlined process for continuous fiber additive manufacturing. Meanwhile, the optimized non-perforated and perforated MBB beams after discrete fiber continuous treatment, are manufactured using continuous fiber co-extrusion additive manufacturing technology to verify the effectiveness of the variable stiffness fiber optimization framework proposed in this paper.
文摘BACKGROUND Surgery is the first choice of treatment for patients with colorectal cancer.Traditional open surgery imparts great damage to the body of the patient and can easily cause adverse stress reactions.With the continuous development of medical technology,laparoscopic minimally invasive surgery has shown great advantages for the treatment of patients with celiac disease.AIM To investigate the short-term efficacy of laparoscopic radical surgery and traditional laparotomy for the treatment of colorectal cancer,and the differences in the risk analysis of unplanned reoperation after operation.METHODS As the research subjects,this study selected 100 patients with colorectal cancer who received surgical treatment at the Yulin First Hospital from January 2018 to January 2022.Among them,50 patients who underwent laparoscopic radical resection were selected as the research group and 50 patients who underwent traditional laparotomy were selected as the control group.Data pertaining to clinical indexes,gastrointestinal hormones,nutrition indexes,the levels of inflammatory factors,quality of life,Visual Analog Scale score,and the postoperative complications of the two groups of patients before and after treatment were collected,and the therapeutic effects in the two groups were analyzed and compared.RESULTS Compared with the control group,perioperative bleeding,peristalsis recovery time,and hospital stays were significantly shorter in the research group.After surgery,the levels of gastrin(GAS)and motilin(MTL)were decreased in both groups,and the fluctuation range of GAS and MTL observed in the research group was significantly lower than that recorded in the control group.The hemoglobin(Hb)levels increased after surgery,and the level of Hb in the research group was significantly higher compared with the control group.After the operation,the expression levels of tumor necrosis factor-α,interleukin-6,and C-reactive protein and the total incidence of complications were significantly lower in the research group compared with the control group.One year after the operation,the quality of life of the two groups was greatly improved,with the quality of life in the research group being significantly better.CONCLUSION Laparoscopy was effective for colorectal surgery by reducing the occurrence of complications and inflammatory stress reaction;moreover,the quality of life of patients was significantly improved,which warrants further promotion.
基金supported by Doctoral Scientific Research Starting Foundation of Jingdezhen Ceramic University(Grant No.102/01003002031)Re-accompanying Funding Project of Academic Achievements of Jingdezhen Ceramic University(Grant Nos.215/20506277,215/20506341)。
文摘The complete convergence for weighted sums of sequences of independent,identically distributed random variables under sublinear expectation space is studied.By moment inequality and truncation methods,we establish the equivalent conditions of complete convergence for weighted sums of sequences of independent,identically distributed random variables under sublinear expectation space.The results complement the corresponding results in probability space to those for sequences of independent,identically distributed random variables under sublinear expectation space.