Hua Shou(1304-1386)styled himself Ying Ning Sheng.He was also known as Hua Boren.His ancestral home was in Xiang Town,Xu Prefecture(present Xuchang,Henan province).His birth place was Yizhen,Jiangsu province.Later he ...Hua Shou(1304-1386)styled himself Ying Ning Sheng.He was also known as Hua Boren.His ancestral home was in Xiang Town,Xu Prefecture(present Xuchang,Henan province).His birth place was Yizhen,Jiangsu province.Later he moved to Yuyao,Zhejiang province.He was one of the distinguished practitioners of the late Yuan and early Ming dynasties.His writings include Elaboration of the Fourteen Meridians(Shi Si Jing Fa Hui),Notes on Handwritten Copy of Basic Questions(Du Su Wen Chao),The Essentials for Physicians(Zhen Jia Shu Yao).展开更多
From a very early period,the Chinese already vaguely sensed that the cultivation of crops required an intricate system.The third century BCE work Master Lü’s Spring and Autumn Annals(Lüshi chunqiu吕氏春秋)s...From a very early period,the Chinese already vaguely sensed that the cultivation of crops required an intricate system.The third century BCE work Master Lü’s Spring and Autumn Annals(Lüshi chunqiu吕氏春秋)states that crops were fed by heaven and raised by earth,and that harvests depended on the farmers who worked the land.Therefore,these three elements,that is,heaven,earth,and farmers,together with crops,jointly constituted a complex community.According to the ancient Chinese,moving a crop away from its native place could bring huge benefits to the new area to which the crop was moved.When writing and compiling Fundamentals of Agriculture and Sericulture(Nongsang jiyao农桑辑要),the officials of the Agricultural Extension Bureau司农司in the Yuan dynasty(1271–1368)excitedly noted the changes brought about by non-native crops to the agriculture of the Central Plains of China中原:“Ramie(Boehmeria nivea)is a crop native to southern China,while cotton(Gossypium herbaceum)comes from the Western Regions西域.In recent years,nevertheless,ramie has been introduced to Henan,while cotton has started to be planted in Shaanxi.The two crops thrive and show no difference from local crops.Farmers in the two regions benefit a lot therefrom”(Agricultural Extension Bureau 1888,juan 2:21).展开更多
Granulomatosis with polyangiitis(GPA)poses significant therapeutic challenges due to its susceptibility to concurrent infections and frequent relapses.Professor SHI Zaixiang proposed the therapeutic theory of lifting ...Granulomatosis with polyangiitis(GPA)poses significant therapeutic challenges due to its susceptibility to concurrent infections and frequent relapses.Professor SHI Zaixiang proposed the therapeutic theory of lifting depression and removing blood stasis,resolving phlegm and dispelling nodulation for GPA management.He identified the core pathogenesis as“Qi collapse with collateral obstruction and phlegm-stasis intermingling”,establishing the treatment principle of comprehensive intervention through ascending ancestral Qi,activating blood circulation,and resolving phlegm-stasis nodules.In clinical practice,Professor SHI emphasizes maintaining immune homeostasis with herbal medicine to enhance efficiency,while dynamically balancing Qi,blood,Yin,and Yang.Notably,he highlights the critical role of emotional factors in autoimmune disease progression.A representative case was provided to elucidate his clinical reasoning in GPA treatment.展开更多
When examining the exchange between Chinese and Western medicine during the late Ming and early Qing dynasties,Wang Honghan(王宏翰)stands out as the only Chinese physician who has been thoroughly discussed to date.How...When examining the exchange between Chinese and Western medicine during the late Ming and early Qing dynasties,Wang Honghan(王宏翰)stands out as the only Chinese physician who has been thoroughly discussed to date.However,Zhu Shi(祝石)holds a distinct position as the earliest known Chinese to receive Western medical training,extensively practice Western medicine in China,and leave behind medical writings.Drawing on Western anatomical knowledge,Zhu Shi reevaluated traditional Chinese medicine(TCM)and even incorporated distillation techniques into his clinical practice.This paper primarily focuses on Zhu Shi,with comparative reference to Wang Honghan,exploring their medical learning journeys,reflections on TCM,attitudes toward anatomy,Zhu Shi’s influence on Wang Honghan,and their respective medical practices.Through such comparative analysis,this study provides deeper insights into the integration of Chinese and Western medicine during the early Qing dynasty.展开更多
Su Shi can be described as a true genius of his time.Whether in poetry,lyrics,songs,fu,or in life itself,his charismatic personality and rare optimism make him a once-in-a-century talent.This paper takes Su Shi’s poe...Su Shi can be described as a true genius of his time.Whether in poetry,lyrics,songs,fu,or in life itself,his charismatic personality and rare optimism make him a once-in-a-century talent.This paper takes Su Shi’s poems as a guiding thread and explores the conceptual spirit and practical significance reflected in four works:The Cold Food Observance,The Complete Works of Su Dongpo:An Account of Paintings at Jingyin Temple,and Xiaoxiang Bamboo and Stone Map,analyzing them from an artistic perspective.It strives to reveal the profound humanistic sentiments Su Shi evoked in the vast,ever-changing world,as well as the pure and exquisite poetic and pictorial beauty he bestowed upon it.展开更多
Sesame(Sesamum indicum L.)is an ancient oilseed crop of the Pedaliaceae family with high oil content and potential health benefits.SHI RELATED SEQUENCE(SRS)proteins are the transcription factors(TFs)specific to plants...Sesame(Sesamum indicum L.)is an ancient oilseed crop of the Pedaliaceae family with high oil content and potential health benefits.SHI RELATED SEQUENCE(SRS)proteins are the transcription factors(TFs)specific to plants that contain RING-like zinc finger domain and are associated with the regulation of several physiological and biochemical processes.They also play vital roles in plant growth and development such as root formation,leaf development,floral development,hormone biosynthesis,signal transduction,and biotic and abiotic stress responses.Nevertheless,the SRS gene family was not reported in sesame yet.In this study,identification,molecular characterization,phylogenetic relationship,cis-acting regulatory elements,protein-protein interaction,syntenic relationship,duplication events and expression pattern of SRS genes were analyzed in S.indicum.We identified total six SiSRS genes on seven different linkage groups in the S.indicum genome by comparing with the other species,including the model plant Arabidopsis thaliana.The SiSRS genes showed variation in their structure like2–5 exons and 1–4 introns.Like other species,SiSRS proteins also contained‘RING-like zinc finger'and‘LRP1'domains.Then,the SiSRS genes were clustered into subclasses via phylogenetic analysis with proteins of S.indicum,A.thaliana,and some other plant species.The cis-acting regulatory elements analysis revealed that the promoter region of SiSRS4(SIN_1011561)showed the highest 13 and 16 elements for light-and phytohormone-responses whereas,SiSRS1(SIN_1015187)showed the highest 15 elements for stress-response.The ABREs,or ABA-responsive elements,were found in a maximum of 8 copies in the SiSRS3(SIN 1009100).Moreover,the available RNA-seq based expression of SiSRS genes revealed variation in expression patterns between stress-treated and non-treated samples,especially in drought and salinity conditions in.S.indicum.Two SiSRS genes like SiSRS1(SIN_1015187)and SiSRS5(SIN_1021065),also exhibited variable expression patterns between control vs PEG-treated sesame root samples and three SiSRS genes,including SiSRS1(SIN_1015187),SiSRS2(SIN_1003328)and SiSRS5(SIN_1021065)were responsive to salinity treatments.The present outcomes will encourage more research into the gene expression and functionality analysis of SiSRS genes in S.indicum and other related species.展开更多
The current academic research on the Dian Shi Zhai Pictorial founded in 1884 has been perfected,but there is very little research on the Flying Shadow Pavilion Pictorial,which can be said to be derived from Dian Shi Z...The current academic research on the Dian Shi Zhai Pictorial founded in 1884 has been perfected,but there is very little research on the Flying Shadow Pavilion Pictorial,which can be said to be derived from Dian Shi Zhai Pictorial terms of both content and form,and which was founded by the Haiist painter Wu Youru in 1890 in order to reward the increasing number of admirers,but it is still in the initial stage.Flying Shadow Pavilion Pictorial consisted of four parts:pictures of ladies in Shanghai costumes,news about current affairs,pictures of animals,and compilations of women,each of which was accompanied by the then popular notebooks,which were popular at the time among the then readers because of the matching of pictures with text and the mixing of narratives and discussions.This paper takes Flying Shadow Pavilion Pictorial as the main object,summarizes the existing literature about Flying Shadow Pavilion Pictorial,points out the deficiencies of the current research on this basis,and points out the development trend of Flying Shadow Pavilion Pictorial in the future research.展开更多
This paper comparatively examines the Res Gestae of Augustus(r.27 BC–AD 14)and the stelae inscriptions of Qin Shi Huangdi(r.221–210 BC),the first emperors of Rome and China respectively.It shows how the two emperors...This paper comparatively examines the Res Gestae of Augustus(r.27 BC–AD 14)and the stelae inscriptions of Qin Shi Huangdi(r.221–210 BC),the first emperors of Rome and China respectively.It shows how the two emperors justified and consolidated their regimes by unifying the two antithetical themes of war and peace in their propagandistic self-portrayals.It argues that both emperors,due to the socio-political pressure of their milieus,depicted themselves predominantly as guardians of a peace that was constantly under threat by impious and immoral outside forces,against which only the emperors themselves could be victorious and sustain this new peace.展开更多
This study explores the application value of Zhao Shi Lei-huo-jiu in managing common postoperative gastrointestinal symptom clusters following rectal cancer surgery,under the framework of the Enhanced Recovery After S...This study explores the application value of Zhao Shi Lei-huo-jiu in managing common postoperative gastrointestinal symptom clusters following rectal cancer surgery,under the framework of the Enhanced Recovery After Surgery(ERAS)concept.By detailing the development,core elements,and application of ERAS in colorectal surgery,combined with the historical origins,unique techniques,and mechanisms of Zhao Shi Lei-huo-jiu,this paper highlights the innovation of integrating traditional Chinese medicine treatments with modern surgical recovery principles.Through a rigorously designed research process,rectal cancer postoperative patients were selected as research subjects,and the data collection and implementation steps were explicitly outlined.The study results provide scientific evidence for the practical efficacy and advantages of Zhao Shi Lei-huo-jiu in postoperative rehabilitation for rectal cancer,offering significant practical implications for guiding clinical practice and promoting early patient recovery.展开更多
本试验利用蔷薇科植物提取物(SHY)分别与新城疫、禽流感H9、H5亚型病毒作用后,接种10 d SPF鸡胚,评价SHY对病毒的抑制作用;给21 d SPF鸡连续口服该中药提取物5 d后,分别用新城疫、禽流感病毒攻击,观察对SPF鸡的保护作用。结果表明:SHY...本试验利用蔷薇科植物提取物(SHY)分别与新城疫、禽流感H9、H5亚型病毒作用后,接种10 d SPF鸡胚,评价SHY对病毒的抑制作用;给21 d SPF鸡连续口服该中药提取物5 d后,分别用新城疫、禽流感病毒攻击,观察对SPF鸡的保护作用。结果表明:SHY测试剂量对SPF鸡胚没有毒性;20、10、5和2.5 mg/mL提取物与一定量的新城疫、禽流感H9亚型病毒作用后,鸡胚全部存活,病毒测定为阴性;与禽流感H5亚型病毒作用后,2.5 mg/mL组不能完全保护鸡胚存活(6/8),病毒分离阳性。在攻毒试验中,SPF鸡分别按60、50、40和20 mg口服后,用新城疫和禽流感H9亚型攻毒保护分别为5/5、5/5、5/5和4/5。显示SHY不但能显著抑制新城疫、禽流感H9和H5亚型在鸡胚上增殖,而且能保护新城疫、禽流感H9亚型病毒的攻击。对SHY深入的研究,有望开发出有效抗禽流感药物。展开更多
针对具有多维状态变量、多种工作模式和故障模式的复杂工程系统,提出一种基于综合健康指数(synthesized health index,SHI)与相关向量机(relevance vector machine,RVM)的系统级失效预测方法。在离线训练阶段,先根据有限失效历史数据建...针对具有多维状态变量、多种工作模式和故障模式的复杂工程系统,提出一种基于综合健康指数(synthesized health index,SHI)与相关向量机(relevance vector machine,RVM)的系统级失效预测方法。在离线训练阶段,先根据有限失效历史数据建立各工作模式下的健康评估模型,并据此获得各历史退化轨迹的SHI序列;然后再使用RVM对这些序列进行回归处理,进而辨识出与回归曲线最为匹配的函数模型。在线预测阶段,先运用健康评估模型计算当前设备的SHI序列并进行RVM回归,再拟合出离线阶段确定的函数模型并添加时变噪声;最后,外推预测出系统剩余使用寿命的概率密度分布。该方法成功应用到涡轮发动机的失效预测案例。展开更多
文摘Hua Shou(1304-1386)styled himself Ying Ning Sheng.He was also known as Hua Boren.His ancestral home was in Xiang Town,Xu Prefecture(present Xuchang,Henan province).His birth place was Yizhen,Jiangsu province.Later he moved to Yuyao,Zhejiang province.He was one of the distinguished practitioners of the late Yuan and early Ming dynasties.His writings include Elaboration of the Fourteen Meridians(Shi Si Jing Fa Hui),Notes on Handwritten Copy of Basic Questions(Du Su Wen Chao),The Essentials for Physicians(Zhen Jia Shu Yao).
文摘From a very early period,the Chinese already vaguely sensed that the cultivation of crops required an intricate system.The third century BCE work Master Lü’s Spring and Autumn Annals(Lüshi chunqiu吕氏春秋)states that crops were fed by heaven and raised by earth,and that harvests depended on the farmers who worked the land.Therefore,these three elements,that is,heaven,earth,and farmers,together with crops,jointly constituted a complex community.According to the ancient Chinese,moving a crop away from its native place could bring huge benefits to the new area to which the crop was moved.When writing and compiling Fundamentals of Agriculture and Sericulture(Nongsang jiyao农桑辑要),the officials of the Agricultural Extension Bureau司农司in the Yuan dynasty(1271–1368)excitedly noted the changes brought about by non-native crops to the agriculture of the Central Plains of China中原:“Ramie(Boehmeria nivea)is a crop native to southern China,while cotton(Gossypium herbaceum)comes from the Western Regions西域.In recent years,nevertheless,ramie has been introduced to Henan,while cotton has started to be planted in Shaanxi.The two crops thrive and show no difference from local crops.Farmers in the two regions benefit a lot therefrom”(Agricultural Extension Bureau 1888,juan 2:21).
基金supported by the Seventh Batch of National Academic Experience Inheritance Project for Senior TCM Experts from the National Administration of Traditional Chinese Medicine(No.GZYRJS[2022]76)the Sixth Batch of Beijing Municipal Academic Experience Inheritance Project for TCM Experts from Beijing Administration of Traditional Chinese Medicine(No.JZYKZ[2019]139).
文摘Granulomatosis with polyangiitis(GPA)poses significant therapeutic challenges due to its susceptibility to concurrent infections and frequent relapses.Professor SHI Zaixiang proposed the therapeutic theory of lifting depression and removing blood stasis,resolving phlegm and dispelling nodulation for GPA management.He identified the core pathogenesis as“Qi collapse with collateral obstruction and phlegm-stasis intermingling”,establishing the treatment principle of comprehensive intervention through ascending ancestral Qi,activating blood circulation,and resolving phlegm-stasis nodules.In clinical practice,Professor SHI emphasizes maintaining immune homeostasis with herbal medicine to enhance efficiency,while dynamically balancing Qi,blood,Yin,and Yang.Notably,he highlights the critical role of emotional factors in autoimmune disease progression.A representative case was provided to elucidate his clinical reasoning in GPA treatment.
基金financed by the grant from the 2024 Tianjin Philosophy and Social Science Planning Annual Program(No.TJZLQN24-002).
文摘When examining the exchange between Chinese and Western medicine during the late Ming and early Qing dynasties,Wang Honghan(王宏翰)stands out as the only Chinese physician who has been thoroughly discussed to date.However,Zhu Shi(祝石)holds a distinct position as the earliest known Chinese to receive Western medical training,extensively practice Western medicine in China,and leave behind medical writings.Drawing on Western anatomical knowledge,Zhu Shi reevaluated traditional Chinese medicine(TCM)and even incorporated distillation techniques into his clinical practice.This paper primarily focuses on Zhu Shi,with comparative reference to Wang Honghan,exploring their medical learning journeys,reflections on TCM,attitudes toward anatomy,Zhu Shi’s influence on Wang Honghan,and their respective medical practices.Through such comparative analysis,this study provides deeper insights into the integration of Chinese and Western medicine during the early Qing dynasty.
文摘Su Shi can be described as a true genius of his time.Whether in poetry,lyrics,songs,fu,or in life itself,his charismatic personality and rare optimism make him a once-in-a-century talent.This paper takes Su Shi’s poems as a guiding thread and explores the conceptual spirit and practical significance reflected in four works:The Cold Food Observance,The Complete Works of Su Dongpo:An Account of Paintings at Jingyin Temple,and Xiaoxiang Bamboo and Stone Map,analyzing them from an artistic perspective.It strives to reveal the profound humanistic sentiments Su Shi evoked in the vast,ever-changing world,as well as the pure and exquisite poetic and pictorial beauty he bestowed upon it.
文摘Sesame(Sesamum indicum L.)is an ancient oilseed crop of the Pedaliaceae family with high oil content and potential health benefits.SHI RELATED SEQUENCE(SRS)proteins are the transcription factors(TFs)specific to plants that contain RING-like zinc finger domain and are associated with the regulation of several physiological and biochemical processes.They also play vital roles in plant growth and development such as root formation,leaf development,floral development,hormone biosynthesis,signal transduction,and biotic and abiotic stress responses.Nevertheless,the SRS gene family was not reported in sesame yet.In this study,identification,molecular characterization,phylogenetic relationship,cis-acting regulatory elements,protein-protein interaction,syntenic relationship,duplication events and expression pattern of SRS genes were analyzed in S.indicum.We identified total six SiSRS genes on seven different linkage groups in the S.indicum genome by comparing with the other species,including the model plant Arabidopsis thaliana.The SiSRS genes showed variation in their structure like2–5 exons and 1–4 introns.Like other species,SiSRS proteins also contained‘RING-like zinc finger'and‘LRP1'domains.Then,the SiSRS genes were clustered into subclasses via phylogenetic analysis with proteins of S.indicum,A.thaliana,and some other plant species.The cis-acting regulatory elements analysis revealed that the promoter region of SiSRS4(SIN_1011561)showed the highest 13 and 16 elements for light-and phytohormone-responses whereas,SiSRS1(SIN_1015187)showed the highest 15 elements for stress-response.The ABREs,or ABA-responsive elements,were found in a maximum of 8 copies in the SiSRS3(SIN 1009100).Moreover,the available RNA-seq based expression of SiSRS genes revealed variation in expression patterns between stress-treated and non-treated samples,especially in drought and salinity conditions in.S.indicum.Two SiSRS genes like SiSRS1(SIN_1015187)and SiSRS5(SIN_1021065),also exhibited variable expression patterns between control vs PEG-treated sesame root samples and three SiSRS genes,including SiSRS1(SIN_1015187),SiSRS2(SIN_1003328)and SiSRS5(SIN_1021065)were responsive to salinity treatments.The present outcomes will encourage more research into the gene expression and functionality analysis of SiSRS genes in S.indicum and other related species.
文摘The current academic research on the Dian Shi Zhai Pictorial founded in 1884 has been perfected,but there is very little research on the Flying Shadow Pavilion Pictorial,which can be said to be derived from Dian Shi Zhai Pictorial terms of both content and form,and which was founded by the Haiist painter Wu Youru in 1890 in order to reward the increasing number of admirers,but it is still in the initial stage.Flying Shadow Pavilion Pictorial consisted of four parts:pictures of ladies in Shanghai costumes,news about current affairs,pictures of animals,and compilations of women,each of which was accompanied by the then popular notebooks,which were popular at the time among the then readers because of the matching of pictures with text and the mixing of narratives and discussions.This paper takes Flying Shadow Pavilion Pictorial as the main object,summarizes the existing literature about Flying Shadow Pavilion Pictorial,points out the deficiencies of the current research on this basis,and points out the development trend of Flying Shadow Pavilion Pictorial in the future research.
文摘This paper comparatively examines the Res Gestae of Augustus(r.27 BC–AD 14)and the stelae inscriptions of Qin Shi Huangdi(r.221–210 BC),the first emperors of Rome and China respectively.It shows how the two emperors justified and consolidated their regimes by unifying the two antithetical themes of war and peace in their propagandistic self-portrayals.It argues that both emperors,due to the socio-political pressure of their milieus,depicted themselves predominantly as guardians of a peace that was constantly under threat by impious and immoral outside forces,against which only the emperors themselves could be victorious and sustain this new peace.
文摘This study explores the application value of Zhao Shi Lei-huo-jiu in managing common postoperative gastrointestinal symptom clusters following rectal cancer surgery,under the framework of the Enhanced Recovery After Surgery(ERAS)concept.By detailing the development,core elements,and application of ERAS in colorectal surgery,combined with the historical origins,unique techniques,and mechanisms of Zhao Shi Lei-huo-jiu,this paper highlights the innovation of integrating traditional Chinese medicine treatments with modern surgical recovery principles.Through a rigorously designed research process,rectal cancer postoperative patients were selected as research subjects,and the data collection and implementation steps were explicitly outlined.The study results provide scientific evidence for the practical efficacy and advantages of Zhao Shi Lei-huo-jiu in postoperative rehabilitation for rectal cancer,offering significant practical implications for guiding clinical practice and promoting early patient recovery.
文摘本试验利用蔷薇科植物提取物(SHY)分别与新城疫、禽流感H9、H5亚型病毒作用后,接种10 d SPF鸡胚,评价SHY对病毒的抑制作用;给21 d SPF鸡连续口服该中药提取物5 d后,分别用新城疫、禽流感病毒攻击,观察对SPF鸡的保护作用。结果表明:SHY测试剂量对SPF鸡胚没有毒性;20、10、5和2.5 mg/mL提取物与一定量的新城疫、禽流感H9亚型病毒作用后,鸡胚全部存活,病毒测定为阴性;与禽流感H5亚型病毒作用后,2.5 mg/mL组不能完全保护鸡胚存活(6/8),病毒分离阳性。在攻毒试验中,SPF鸡分别按60、50、40和20 mg口服后,用新城疫和禽流感H9亚型攻毒保护分别为5/5、5/5、5/5和4/5。显示SHY不但能显著抑制新城疫、禽流感H9和H5亚型在鸡胚上增殖,而且能保护新城疫、禽流感H9亚型病毒的攻击。对SHY深入的研究,有望开发出有效抗禽流感药物。
文摘针对具有多维状态变量、多种工作模式和故障模式的复杂工程系统,提出一种基于综合健康指数(synthesized health index,SHI)与相关向量机(relevance vector machine,RVM)的系统级失效预测方法。在离线训练阶段,先根据有限失效历史数据建立各工作模式下的健康评估模型,并据此获得各历史退化轨迹的SHI序列;然后再使用RVM对这些序列进行回归处理,进而辨识出与回归曲线最为匹配的函数模型。在线预测阶段,先运用健康评估模型计算当前设备的SHI序列并进行RVM回归,再拟合出离线阶段确定的函数模型并添加时变噪声;最后,外推预测出系统剩余使用寿命的概率密度分布。该方法成功应用到涡轮发动机的失效预测案例。
