Objective: Ultrasonically activated shears (UAS) have been applied in open gastric surgeries with no or little evidence. It was previously reported about the surgical outcome and effectiveness of UAS based on a ran...Objective: Ultrasonically activated shears (UAS) have been applied in open gastric surgeries with no or little evidence. It was previously reported about the surgical outcome and effectiveness of UAS based on a randomized controlled trial of 256 patients with gastric cancer. We aimed to clarify the long-term oncological safety of the use of UAS in the aspect of overall survival and recurrence.Methods: Gastric cancer patients who underwent gastrectomy with D2 lymph node dissection were enrolled and randomly assigned to either the conventional surgery group (n=125) or the UAS group (n=128). Survival, recurrence and long-term postoperative complications were compared between the two groups. The median follow-up period was 56 months.Results: Gastric cancer-related death was higher in patients of the UAS group compared with the conventional group (P=0.019). Overall survival rates stratified by stage were not significantly different between the two groups (P=0.170). Disease-free survival rates stratified by stage and recurrence-free survival rates of gastric cancer were similar between the conventional group and the UAS group (P=0.313 and 0.199, respectively). The postoperative complication rate was not significantly different between the groups (P=1.000). Conclusions: It is suggested that the use of UAS in gastrectomy for gastric cancer showed oncologically acceptable safety compared with conventional electric instruments even in long-term period.展开更多
Background: Ultrasonic energy devices are utilized for transection, incision, and hemostasis in traditional open and laparoscopic procedures. The Harmonic HD 1000i Shears, designed to deliver a precise amount of therm...Background: Ultrasonic energy devices are utilized for transection, incision, and hemostasis in traditional open and laparoscopic procedures. The Harmonic HD 1000i Shears, designed to deliver a precise amount of thermal energy during tissue transection and vessel sealing, has been utilized in many specialties. This study aimed to confirm real-world safety and performance of the Harmonic device in two thoracoscopic procedures: lobectomy and segmentectomy. Methods: The primary endpoint of this retrospective, observational, single-arm study was rate of post-operative blood transfusions related to study device or procedure. Secondary endpoints included occurrence of intra- and post-operative adverse events (AEs) or complications device- or procedure-related, and rate of required additional hemostatic measures. Adults included those who underwent thoracoscopic lobectomy or segmentectomy where HD 1000i shears were used while excluding those where additional advanced energy devices were used. The study was conducted at Severance Hospital, Yonsei University Health System, South Korea from May 1, 2018, to November 30, 2020. Results: Subjects included n = 766 lobectomies (mean age 63.79, 52% male) and n = 215 segmentectomies (mean age 63.19, 54% male). Estimated blood loss was 50 mL (0 min, 3200 max) and 20 mL (0 min, 800 max), intraoperative transfusion rate 0.001% and 0%, intraoperative complication/AE rate 1% and 2%, and post-operative complication/AE rate 9% and 4% in the lobectomy and segmentectomy groups, respectively. Median operative times were 108 min. (35 min, 395 max) for lobectomies and 105 min. (32 min, 574 max) for segmentectomies. Conclusion: Given the low rate of blood loss and intra- and post-operative complication/AE rates, HD 1000i can be used confidently for thoracoscopic pulmonary resection in adults.展开更多
Focal adhesions are polyproteins linked to extracellular matrix and cytoskeleton,which play an important role in the process of transforming force signals into intracellular chemical signals and subsequently triggerin...Focal adhesions are polyproteins linked to extracellular matrix and cytoskeleton,which play an important role in the process of transforming force signals into intracellular chemical signals and subsequently triggering related physiological or pathological reactions.The cytoskeleton is a network of protein fibers in the cytoplasm,which is composed of microfilaments,microtubules,intermediate filaments,and cross-linked proteins.It is a very important structure for cells to maintain their basic morphology.This review summarizes the process of fluid shear stress transduction mediated by focal adhesion and the key role of the cytoskeleton in this process,which focuses on the focal adhesion and cytoskeleton systems.The important proteins involved in signal transduction in focal adhesion are introduced emphatically.The relationship between focal adhesion and mechanical transduction pathways are discussed.In this review,we discuss the relationship between fluid shear stress and associated diseases such as atherosclerosis,as well as its role in clinical research and drug development.展开更多
Strain-rate frequency superposition(SRFS) is often employed to probe the low-frequency behavior of soft solids under oscillatory shear in anticipated linear response. However, physical interpretation of an apparently ...Strain-rate frequency superposition(SRFS) is often employed to probe the low-frequency behavior of soft solids under oscillatory shear in anticipated linear response. However, physical interpretation of an apparently well-overlapped master curve generated by SRFS has to combine with nonlinear analysis techniques such as Fourier transform rheology and stress decomposition method. The benefit of SRFS is discarded when some inconsistencies of the shifted master curves with the canonical linear response are observed. In this work, instead of evaluating the SRFS in full master curves, two criteria were proposed to decompose the original SRFS data and to delete the bad experimental data. Application to Carabopol suspensions indicates that good master curves could be constructed based upon the modified data and the high-frequency deviations often observed in original SRFS master curves are eliminated. The modified SRFS data also enable a better quantitative description and the evaluation of the apparent structural relaxation time by the two-mode fractional Maxwell model.展开更多
Nowadays,enterprise customers have higher and higher requirements for steel plate quality,and the performance research of shearing machine has been widely paid attention to.In this paper,the finite element analysis so...Nowadays,enterprise customers have higher and higher requirements for steel plate quality,and the performance research of shearing machine has been widely paid attention to.In this paper,the finite element analysis software ANSYS is used to analyze and verify the key parts of the downcut inclined blade shears.Through continuous analysis and improvement of the model,the weak points areoptimized to improve the shear performance andproduction efficiency of the shears.展开更多
The influence of Hf on the precipitation behavior of γ'phase and the subsequent tensile properties of a Ni-Cr-Mo alloy after long-term thermal exposure was investigated.The results reveal that the addition of Hf ...The influence of Hf on the precipitation behavior of γ'phase and the subsequent tensile properties of a Ni-Cr-Mo alloy after long-term thermal exposure was investigated.The results reveal that the addition of Hf increases the average diameter ofγ'phases after thermal exposure at 700℃ for 5000 h,which enhances the critical resolved shear stress required for dislocations to shear the γ'phases in the Ni-Cr-Mo alloy.Simultaneously,element Hf incorporated into the γ'phases increases the lattice mismatch between the γ'and γ phase,thereby strengthening the coherency strengthening effect.These two factors collectively contribute to the enhanced strength of the alloy.Thus,Hf alloying effectively improves the yield strength of the Ni-Cr-Mo alloy after thermal exposure at 700℃.展开更多
Using the new two-dimensional cranking relativistic mean field (RMF) approach, the shears mechanism of magnetic rotation based on configuration πh121/2νh-211/2 in 142Gd is microscopically and self-consistently exami...Using the new two-dimensional cranking relativistic mean field (RMF) approach, the shears mechanism of magnetic rotation based on configuration πh121/2νh-211/2 in 142Gd is microscopically and self-consistently examined by investigating the aligning angular momenta of the valence nucleons.展开更多
Arteriovenous fistula(AVF)calcification is a common complication in hemodialysis patients that leads to AVF dysfunction and decreases the AVF survival,but the mechanisms of AVF calcification,especially the role of hem...Arteriovenous fistula(AVF)calcification is a common complication in hemodialysis patients that leads to AVF dysfunction and decreases the AVF survival,but the mechanisms of AVF calcification,especially the role of hemodynamic changes in AVF calcification have not been fully investigated.In this study,a computational fluid dynamics(CFD)model was carried out based on AVF,at the distal anastomosis of the cephalic vein and radial artery,generated from a patient-specific computed tomography(CT)angiography and Doppler ultrasound image.Hemodynamic factors were considered to explore the mechanisms responsible for the initiation and progression of AVF calcification.Five stages in one cardiac cycle were chosen to be studied for the velocity field,pressure,time-averaged wall shear stress(TAWSS),and oscillatory shear index(OSI).Blood pressure was higher in the arteriovenous anastomosis,and variations of great amplitude of pressure were examined during the cardiac cycle.Blood pressure,transient shear stress,TAWSS,and OSI were higher in the arteriovenous anastomosis and at the bottom of expanded outflow vein,and these sites were highly consistent with the calcified areas shown on CT angiography.On the contrary,no calcification was found in sites where streamline was stable,blood pressure did not change dramatically,as well as TAWSS and OSI were lower.It was shown that AVF calcification was correlated with hemodynamic changes,which may contribute to further understanding the mechanisms of AVF calcification and providing scientific evidence to inform the optimization of surgical strategies and the development of personalized interventional measures in clinical contexts.展开更多
The negative Poisson’s ratio(NPR)bolt is an innovative support element distinguished by its high strength,elongation,and a slightly negative Poisson’s ratio.Unlike conventional prestressed(PR)bolts with a positive P...The negative Poisson’s ratio(NPR)bolt is an innovative support element distinguished by its high strength,elongation,and a slightly negative Poisson’s ratio.Unlike conventional prestressed(PR)bolts with a positive Poisson’s ratio,the NPR bolt exhibits a quasi-ideal plastic response without a prominent yield platform,enabling it to sustain high prestress with a substantial safety margin,which is particularly advantageous for jointed rock masses.However,investigations into the shear resistance mechanisms of NPR bolts under varying prestress levels remain limited.This study conducted full-scale double shear tests to assess the shear strength,deformation behavior,energy absorption,and failure mechanisms of NPR bolts under different prestress conditions.To ensure a fair comparison with PR bolts,a prestress utilization coefficient(PUC)was introduced.The results reveal that at a PUC of 0.25,the NPR bolt achieved peak axial force,shear displacement,and peak shear force values that are 2.41,1.88,and 2.13 times greater than those of the PR bolt,respectively.Shear performance was optimized at a prestress level of 100 kN,with energy absorption reaching 47.1 kJ,which is 2.8 times that of the PR bolt.Furthermore,the necking ratio was significantly reduced,indicating more distributed plastic deformation and delayed failure.Field applications verified the superior performance,resulting in a 27.4%reduction in roof settlement and enhanced structural integrity.These findings confirm that NPR bolts possess excellent shear resistance,energy absorption,and deformation adaptability,and optimizing prestress significantly enhances their support performance,providing a strong basis for geotechnical engineering applications.展开更多
High rock temperature is a great challenge frequently encountered during subsurface resource recovery and deep underground space utilization,and it is still unclear how the granitic rock responds to realtime high temp...High rock temperature is a great challenge frequently encountered during subsurface resource recovery and deep underground space utilization,and it is still unclear how the granitic rock responds to realtime high temperature upon shear loading.To better understand the shear fracture behavior and underlying processes of intact granite exposed to thermal-mechanical coupling loading,direct shear tests were conducted utilizing a newly built testing apparatus at varied normal stresses and high temperatures.Influencesof different temperatures and different heating methods(real-time heating and thermal treatment)on the shear mechanical behavior were compared and discussed.Results indicate that shear stress fluctuationswith some small stress drops occur as shear stress is approaching the peak strength under real-time heating,accompanied by more and earlier AE signal uprushes.This suggests that greater cracking events occur earlier during real-time heating than after thermal treatment,resulting in a lower peak shear strength.Furthermore,the peak shear strength,post-peak stress drop,and cohesion rise from room temperature(RT)to 200℃(the peak strength increases by 8%,5.8%,and 9.9%under normal stress of 5 MPa,15 MPa,and 20 MPa,correspondingly),and subsequently decline from 200℃to 400℃.Temperature has a limited impact on shear stiffness from RT to 200℃,but significantlyreduces it from 200℃to 400℃,with drops of 15%,7.9%,and 10%under normal stress of 5 MPa,15 MPa,and 20 MPa,respectively.Moreover,the shear strength and stiffness under real-time heating are lower than those for the thermally treated specimens.The strengthening of intact granite below 200℃upon shear is associated with loss of water and a more compacted structure,while the weakening effect of temperature on shear strength from 200℃to 400℃is due to the new thermal cracks and less brittle and stiff of minerals.展开更多
A novel method that combines reinforced enzyme-induced carbonate precipitation(REICP)was proposed to improve the mechanical properties of dispersive soil.Dispersive soils,which are highly susceptible to erosion caused...A novel method that combines reinforced enzyme-induced carbonate precipitation(REICP)was proposed to improve the mechanical properties of dispersive soil.Dispersive soils,which are highly susceptible to erosion caused by rainfall or seepage,pose significantenvironmental challenges.It is essential to focus on modifying dispersive soil using environmentally friendly methods.This study investigated the cohesion,internal friction angle,permeability,hydrostability test,and microstructure of dispersive soil treated with enzyme-induced carbonate precipitation(EICP)-MgCl2-xanthan gum(REICP),using statistical analysis.A series of laboratory experiments was conducted,including direct shear tests,permeability experiments,mud ball tests,simulated rainfall tests,Fourier transform infrared spectroscopy(FTIR),X-ray diffraction(XRD),and scanning electron microscopy(SEM).The results showed that the combined treatment significantly enhanced the mechanical properties of dispersive soil.At the optimal ratio,cohesion increased by a factor of 2,and the permeability coefficientdecreased by approximately 1.7×10^(7)times.Additionally,the strength parameters gradually increased with curing time.Microstructural analyses indicated that calcite precipitation,pore filling,and ionic redistribution significantlyimproved the mechanical properties and hydrostability of the soil.Statistical analyses showed that EICP materials and xanthan gum increased soil cohesion,while magnesium chloride enhanced the internal friction angle and reduced porosity.This study integrates mechanical testing,statistical analysis,and microstructural evaluation to propose a sustainable and environmentally friendly method for improving dispersive soils.This approach reduces the use of chemical modifiers,minimizes environmental impacts,and demonstrates application potential in the stabilization of dispersive soils.展开更多
This study investigates the width of the secondary eyewall(SE)immediately following its formation in tropical cyclones with surface environmental winds aligned and counter-aligned with environmental vertical wind shea...This study investigates the width of the secondary eyewall(SE)immediately following its formation in tropical cyclones with surface environmental winds aligned and counter-aligned with environmental vertical wind shear(VWS),using idealized numerical experiments.Results reveal that the SE develops greater radial extent when surface winds align with VWS compared to counter-aligned conditions.In alignment configurations,shear-enhanced surface winds on the right flank amplify surface enthalpy fluxes,thereby elevating boundary-layer entropy within the downshear outer-core region.Subsequently,more vigorous outer rainbands develop,inducing marked acceleration of tangential winds in the outer core preceding SE formation.The resultant radial expansion of supergradient winds near the boundary-layer top triggers widespread convective activity immediately beyond the inner core.Progressive axisymmetrization of this convective forcing ultimately generates an expansive SE structure.展开更多
Excavation causes stress redistribution and affects the stress path during the shearing process of rock.The shear strength of rock varies under different stress paths,and the presence of defects reduces the shear stre...Excavation causes stress redistribution and affects the stress path during the shearing process of rock.The shear strength of rock varies under different stress paths,and the presence of defects reduces the shear strength.To further investigate this phenomenon,this study investigates the shear behaviour of rocks with different shear surface integrities under the influenceof different stress paths through laboratory tests and numerical simulations.The results indicate that the shear strength depends on the stress path and a decrease in the shear surface integrity reduces the degree of dependence.The cohesion and friction angle of the Mohr‒Coulomb criterion decrease with weakening of the shear surface integrity.For different stress paths,the direct shear strength is always greater than that of other shear stress paths.The pattern of changes in the acoustic emission count and cumulative count indirectly reflectsthe above findings.Numerical simulations further indicate that the different principal stress states and normal suppression effects during the shearing process lead to changes in the factors of crack propagation,resulting in different mechanical behaviours under various stress paths.For rocks with different integrity levels,the main reason for the different path dependences of shear strength is that the size of the area affected by shear is different.Shear failure will concentrate on the shear plane when the normal inhibition effect is greater.This study explores the mechanism of rock shear behaviour,providing a theoretical basis for establishing more accurate constitutive models and strength criteria.展开更多
We present a novel approach for calculating the energy budget components during the progressive failure process in cohesive-frictional geomaterials.The energy supplied through external loading can be either stored as ...We present a novel approach for calculating the energy budget components during the progressive failure process in cohesive-frictional geomaterials.The energy supplied through external loading can be either stored as elastic strain energy and plastic energy storage or dissipated through damage growth and irreversible plastic deformation mechanisms.Analytical functions describing energy budget components are derived based on a thermodynamic formulation in geomaterials fracture.The thermodynamically consistent derivation leads to a non-local ductile damage model,which is solved numerically in a non-linear finite element framework.The proposed model captures geomaterial fractures in three benchmark examples,including tensile and biaxial-compressive shear scenarios and slope stability analysis.The aspects of shear fracture propagation and energy budget mechanisms are elaborately investigated,considering different material properties and stochastic distributions.The numerical results are validated against existing experimental data and other analytical methods.The model provides a physics-based understanding of energy budget in geomaterials fracture,leading to advances in ground improvement and other geotechnical supporting systems.展开更多
Microwave ablation(MWA)is a minimally invasive technique for treating hepatic tumors,necessitating precise monitoring to ensure treatment efficacy and minimize damage to surrounding tissues.This study explores the pot...Microwave ablation(MWA)is a minimally invasive technique for treating hepatic tumors,necessitating precise monitoring to ensure treatment efficacy and minimize damage to surrounding tissues.This study explores the potential of photoacoustic imaging(PAI)in monitoring MWA by examining ex vivo porcine liver tissues.In this study,a comprehensive analysis of photoacoustic signals was performed to compare the main lobe width(MLW)between ablated and normal regions in porcine liver tissue.Histological staining with succinate dehydrogenase(SDH)and shear wave elastography(SWE)were employed to validate the changes in tissue elasticity after ablation.The analysis demonstrated a notable reduction in the MLW of the average A-lines in ablated tissues compared to nonablated regions(p<0.01).This reduction,attributed to increased tissue density and enhanced elasticity,indicates accelerated sound propagation in thermally ablated areas,which then serves as a critical parameter for mapping tissue characteristics.The reconstruction of the MLW distribution successfully delineated the ablated regions,and was consistent with the results of SDH staining and SWE.In addition,MLW-based imaging exhibited higher spatial resolution compared to SWE.Incorporating MLW analysis into PAI may be a promising strategy to improve the accuracy and effectiveness of MWA monitoring in clinical settings.展开更多
Artificial intelligence(AI)is revolutionizing medical imaging,particularly in chronic liver diseases assessment.AI technologies,including machine learning and deep learning,are increasingly integrated with multiparame...Artificial intelligence(AI)is revolutionizing medical imaging,particularly in chronic liver diseases assessment.AI technologies,including machine learning and deep learning,are increasingly integrated with multiparametric ultrasound(US)techniques to provide more accurate,objective,and non-invasive evaluations of liver fibrosis and steatosis.Analyzing large datasets from US images,AI enhances diagnostic precision,enabling better quantification of liver stiffness and fat content,which are essential for diagnosing and staging liver fibrosis and steatosis.Combining advanced US modalities,such as elastography and doppler imaging with AI,has demonstrated improved sensitivity in identifying different stages of liver disease and distinguishing various degrees of steatotic liver.These advancements also contribute to greater reproducibility and reduced operator dependency,addressing some of the limitations of traditional methods.The clinical implications of AI in liver disease are vast,ranging from early detection to predicting disease progression and evaluating treatment response.Despite these promising developments,challenges such as the need for large-scale datasets,algorithm transparency,and clinical validation remain.The aim of this review is to explore the current applications and future potential of AI in liver fibrosis and steatosis assessment using multiparametric US,highlighting the technological advances and clinical relevance of this emerging field.展开更多
Rock mass stability is significantly influenced by the heterogeneity of rock joint roughness and shear strength.While modern technology facilitates assessing roughness heterogeneity,evaluating shear strength heterogen...Rock mass stability is significantly influenced by the heterogeneity of rock joint roughness and shear strength.While modern technology facilitates assessing roughness heterogeneity,evaluating shear strength heterogeneity remains challenging.To address this,this study first captures the morphology of large-scale(1000 mm × 1000 mm) slate and granite joints via 3D laser scanning.Analysis of these surfaces and corresponding push/pull tests on carved specimens revealed a potential correlation between the heterogeneity of roughness and shear strength.A comparative evaluation of five statistical metrics identified information entropy(Hs) as the most robust indicator for quantifying rock joint heterogeneity.Further analysis using Hsreveals that the heterogeneity is anisotropic and,critically,that shear strength heterogeneity is governed not only by roughness heterogeneity but is also significantly influenced by the mean roughness value,normal stress,and intact rock tensile strength.Consequently,a simple comparison of roughness Hsvalues is insufficient for reliably comparing shear strength heterogeneity.To overcome this limitation,a theoretical framework is developed to explicitly map fundamental roughness statistics(mean and heterogeneity) to shear strength heterogeneity.This framework culminates in a practical workflow that allows for the rapid,field-based assessment of shear strength heterogeneity using readily obtainable rock joint roughness data.展开更多
Root-inspired anchorage systems in the field of bio-inspired geotechnics are renowned for enhancing the pullout capacity of traditional geotechnical anchorage systems by simulating the morphology and architecture of p...Root-inspired anchorage systems in the field of bio-inspired geotechnics are renowned for enhancing the pullout capacity of traditional geotechnical anchorage systems by simulating the morphology and architecture of plant root systems.However,limited studies have explored their practical applications,particularly in improving slope stability.To fill this gap,this study investigates the reinforcement effect of root-inspired anchors on slope stabilization using transparent soil modeling and 3D-printed anchors,and examines the impact of anchor branching patterns(i.e.branching numbers,branching angle,and branching nodes)on slope bearing capacity,shear band evolution,and temporal and spatial variation of slope deformation.The results show that peak slope bearing capacity increases with branching numbers and branching angles,correlating with the envelope area of the curved shear band.Upper anchors result in step-like deflections in the shear band near the trailing edge,while lower anchors convert the upward concave shear band into an upward convex one,thus increasing the slope bearing capacity.Slope deformation is minimized with intermediate branching parameters,such as a branching number of 4 and a branching angle of 45°.The anchor reinforcement mechanisms,i.e.anchor rod shear resistance,interface friction,anchor pullout capacity,and plate tightening effects,are comprehensively discussed,and the installation effects resulting from compromise slope modeling are identified as the contributors.These findings shed light on the failure process of root-inspired anchors reinforced slopes and provide a preliminary reference for potential applications,especially for the tradeoff between anchor branching,slope deformation,and slope stability.展开更多
This study introduces electromagnetic dynamic self-piercing riveting(ED-SPR),an innovative technique that integrates electromagnetic riveting principles with static self-piercing riveting(S-SPR)for highperformance str...This study introduces electromagnetic dynamic self-piercing riveting(ED-SPR),an innovative technique that integrates electromagnetic riveting principles with static self-piercing riveting(S-SPR)for highperformance structural joints.A dedicated methodology and experimental apparatus for ED-SPR were systematically designed and validated.Quantitative comparative analyses between ED-SPR and S-SPR were conducted on three critical material combinations:CFRP/Al,low-strength steel HC340 LA/Al,and high-strength steel DP590/Al.Key findings demonstrate that the electromagnetic-driven process reduces installation resistance by 60%and achieves a 30%larger interlock distance at the joint base compared to S-SPR.These quantitative advantages directly contribute to an approximately 30%increase in load-bearing capacity and superior damage tolerance in ED-SPR joints,as evidenced by tensile-shear testing of single-lap joints.Furthermore,distinct failure modes were observed:ED-SPR joints exhibited top plate pull-out failure in CFRP/Al and DP590/Al configurations,contrasting with the predominant rivet pull-out failure in S-SPR counterparts.Surface morphology and damage evolution were characterized via scanning electron microscopy(SEM)on post-assembly and tensile-failed specimens.The study establishes a foundation for optimizing electromagnetic-driven riveting parameters to mitigate CFRP delamination and further enhance joint reliability in vehicle body and aircraft fuselage structures.展开更多
High geo-stress and high temperature in deep rock engineering increase the possibility of engineering and geological disasters in discontinuous rocks.However,the influence of thermomechanical coupling on the shear beh...High geo-stress and high temperature in deep rock engineering increase the possibility of engineering and geological disasters in discontinuous rocks.However,the influence of thermomechanical coupling on the shear behavior and damage evolution of prefractured granite remains immature.In this context,true triaxial laboratory tests and discrete element method simulations under different confining pressures(σ3=3 MPa,σ2=4 MPa,andσ3=80 MPa,σ2=100 MPa)and temperatures(25℃-500℃)were carried out on rough granite fractures with two different orientations.Results indicate that high temperature and high confining pressure increase the peak strength of the prefractured specimen,leading to more microcracks in the host rock and more gouges between the surfaces.Thermal strengthening at low temperatures(<300℃)and residual stick-slip only occur under a greater confining pressure for prefractured specimens.High confining pressure suppresses generation of the thermal microcracks in the heating stage.Cracks first initiate in the asperities on the fracture surfaces,and then propagate into the rock matrix during the mechanical loading stage.In addition,prefractured granite with a larger fracture angle is characterized by smaller peak and residual strength,faster residual slip,fewer new cracks on the specimen surface,and a more pronounced thermal strengthening effect on peak strength.The slip tendency analysis indicates that a higher maximum principal stress(s1)and a large fracture angle(45°-75°)generally result in a higher potential for fracture slip or activation.This study will contribute to a better understanding of the fracture shear mechanism under true triaxial thermomechanical coupling conditions and provides new insights into the stability evaluation of deep dynamic geological hazards.展开更多
文摘Objective: Ultrasonically activated shears (UAS) have been applied in open gastric surgeries with no or little evidence. It was previously reported about the surgical outcome and effectiveness of UAS based on a randomized controlled trial of 256 patients with gastric cancer. We aimed to clarify the long-term oncological safety of the use of UAS in the aspect of overall survival and recurrence.Methods: Gastric cancer patients who underwent gastrectomy with D2 lymph node dissection were enrolled and randomly assigned to either the conventional surgery group (n=125) or the UAS group (n=128). Survival, recurrence and long-term postoperative complications were compared between the two groups. The median follow-up period was 56 months.Results: Gastric cancer-related death was higher in patients of the UAS group compared with the conventional group (P=0.019). Overall survival rates stratified by stage were not significantly different between the two groups (P=0.170). Disease-free survival rates stratified by stage and recurrence-free survival rates of gastric cancer were similar between the conventional group and the UAS group (P=0.313 and 0.199, respectively). The postoperative complication rate was not significantly different between the groups (P=1.000). Conclusions: It is suggested that the use of UAS in gastrectomy for gastric cancer showed oncologically acceptable safety compared with conventional electric instruments even in long-term period.
文摘Background: Ultrasonic energy devices are utilized for transection, incision, and hemostasis in traditional open and laparoscopic procedures. The Harmonic HD 1000i Shears, designed to deliver a precise amount of thermal energy during tissue transection and vessel sealing, has been utilized in many specialties. This study aimed to confirm real-world safety and performance of the Harmonic device in two thoracoscopic procedures: lobectomy and segmentectomy. Methods: The primary endpoint of this retrospective, observational, single-arm study was rate of post-operative blood transfusions related to study device or procedure. Secondary endpoints included occurrence of intra- and post-operative adverse events (AEs) or complications device- or procedure-related, and rate of required additional hemostatic measures. Adults included those who underwent thoracoscopic lobectomy or segmentectomy where HD 1000i shears were used while excluding those where additional advanced energy devices were used. The study was conducted at Severance Hospital, Yonsei University Health System, South Korea from May 1, 2018, to November 30, 2020. Results: Subjects included n = 766 lobectomies (mean age 63.79, 52% male) and n = 215 segmentectomies (mean age 63.19, 54% male). Estimated blood loss was 50 mL (0 min, 3200 max) and 20 mL (0 min, 800 max), intraoperative transfusion rate 0.001% and 0%, intraoperative complication/AE rate 1% and 2%, and post-operative complication/AE rate 9% and 4% in the lobectomy and segmentectomy groups, respectively. Median operative times were 108 min. (35 min, 395 max) for lobectomies and 105 min. (32 min, 574 max) for segmentectomies. Conclusion: Given the low rate of blood loss and intra- and post-operative complication/AE rates, HD 1000i can be used confidently for thoracoscopic pulmonary resection in adults.
基金the Innovative Research Team of Taizhou Polytechnic College(No.TZYTD-16-4)Natural Science Research General Project of Jiangsu Higher Education Institutions(No.18KJD350002)the Doctoral Research Foundation of Taizhou Polytechnic College(No.1322819004).
文摘Focal adhesions are polyproteins linked to extracellular matrix and cytoskeleton,which play an important role in the process of transforming force signals into intracellular chemical signals and subsequently triggering related physiological or pathological reactions.The cytoskeleton is a network of protein fibers in the cytoplasm,which is composed of microfilaments,microtubules,intermediate filaments,and cross-linked proteins.It is a very important structure for cells to maintain their basic morphology.This review summarizes the process of fluid shear stress transduction mediated by focal adhesion and the key role of the cytoskeleton in this process,which focuses on the focal adhesion and cytoskeleton systems.The important proteins involved in signal transduction in focal adhesion are introduced emphatically.The relationship between focal adhesion and mechanical transduction pathways are discussed.In this review,we discuss the relationship between fluid shear stress and associated diseases such as atherosclerosis,as well as its role in clinical research and drug development.
基金Project(11372263)supported by the National Natural Science Foundation of China
文摘Strain-rate frequency superposition(SRFS) is often employed to probe the low-frequency behavior of soft solids under oscillatory shear in anticipated linear response. However, physical interpretation of an apparently well-overlapped master curve generated by SRFS has to combine with nonlinear analysis techniques such as Fourier transform rheology and stress decomposition method. The benefit of SRFS is discarded when some inconsistencies of the shifted master curves with the canonical linear response are observed. In this work, instead of evaluating the SRFS in full master curves, two criteria were proposed to decompose the original SRFS data and to delete the bad experimental data. Application to Carabopol suspensions indicates that good master curves could be constructed based upon the modified data and the high-frequency deviations often observed in original SRFS master curves are eliminated. The modified SRFS data also enable a better quantitative description and the evaluation of the apparent structural relaxation time by the two-mode fractional Maxwell model.
基金2021 Regional Innovation Joint Fund Project of Natural Science Foundation of Liaoning Province(2021-YKLH-13,2021-YKLH-03).
文摘Nowadays,enterprise customers have higher and higher requirements for steel plate quality,and the performance research of shearing machine has been widely paid attention to.In this paper,the finite element analysis software ANSYS is used to analyze and verify the key parts of the downcut inclined blade shears.Through continuous analysis and improvement of the model,the weak points areoptimized to improve the shear performance andproduction efficiency of the shears.
基金National Key Research and Development Program of China(2021YFB3704103)National Natural Science Foundation of China(51571191)。
文摘The influence of Hf on the precipitation behavior of γ'phase and the subsequent tensile properties of a Ni-Cr-Mo alloy after long-term thermal exposure was investigated.The results reveal that the addition of Hf increases the average diameter ofγ'phases after thermal exposure at 700℃ for 5000 h,which enhances the critical resolved shear stress required for dislocations to shear the γ'phases in the Ni-Cr-Mo alloy.Simultaneously,element Hf incorporated into the γ'phases increases the lattice mismatch between the γ'and γ phase,thereby strengthening the coherency strengthening effect.These two factors collectively contribute to the enhanced strength of the alloy.Thus,Hf alloying effectively improves the yield strength of the Ni-Cr-Mo alloy after thermal exposure at 700℃.
基金Supported by National Natural Science Foundation of China (10705004, 10435010, 10221003)
文摘Using the new two-dimensional cranking relativistic mean field (RMF) approach, the shears mechanism of magnetic rotation based on configuration πh121/2νh-211/2 in 142Gd is microscopically and self-consistently examined by investigating the aligning angular momenta of the valence nucleons.
基金supported by the Scientific Program of Tianjin Municipal Education Commission(Natural Science,Grant No.2022KJ254)Science Foundation of the Second Hospital of Tianjin Medical University(Grant No.2021ydey05)Tianjin Municipal Health Commission Integrated Traditional Chinese and Western Medicine Project(Grant No.2021173).
文摘Arteriovenous fistula(AVF)calcification is a common complication in hemodialysis patients that leads to AVF dysfunction and decreases the AVF survival,but the mechanisms of AVF calcification,especially the role of hemodynamic changes in AVF calcification have not been fully investigated.In this study,a computational fluid dynamics(CFD)model was carried out based on AVF,at the distal anastomosis of the cephalic vein and radial artery,generated from a patient-specific computed tomography(CT)angiography and Doppler ultrasound image.Hemodynamic factors were considered to explore the mechanisms responsible for the initiation and progression of AVF calcification.Five stages in one cardiac cycle were chosen to be studied for the velocity field,pressure,time-averaged wall shear stress(TAWSS),and oscillatory shear index(OSI).Blood pressure was higher in the arteriovenous anastomosis,and variations of great amplitude of pressure were examined during the cardiac cycle.Blood pressure,transient shear stress,TAWSS,and OSI were higher in the arteriovenous anastomosis and at the bottom of expanded outflow vein,and these sites were highly consistent with the calcified areas shown on CT angiography.On the contrary,no calcification was found in sites where streamline was stable,blood pressure did not change dramatically,as well as TAWSS and OSI were lower.It was shown that AVF calcification was correlated with hemodynamic changes,which may contribute to further understanding the mechanisms of AVF calcification and providing scientific evidence to inform the optimization of surgical strategies and the development of personalized interventional measures in clinical contexts.
基金supported by the State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering(Grant No.SDGZ2505)the Postdoctoral Fellowship Program of the China Postdoctoral Science Foundation(Grant No.GZB20250742)the General Program of the China Postdoctoral Science Foundation(Grant No.2025M773213).
文摘The negative Poisson’s ratio(NPR)bolt is an innovative support element distinguished by its high strength,elongation,and a slightly negative Poisson’s ratio.Unlike conventional prestressed(PR)bolts with a positive Poisson’s ratio,the NPR bolt exhibits a quasi-ideal plastic response without a prominent yield platform,enabling it to sustain high prestress with a substantial safety margin,which is particularly advantageous for jointed rock masses.However,investigations into the shear resistance mechanisms of NPR bolts under varying prestress levels remain limited.This study conducted full-scale double shear tests to assess the shear strength,deformation behavior,energy absorption,and failure mechanisms of NPR bolts under different prestress conditions.To ensure a fair comparison with PR bolts,a prestress utilization coefficient(PUC)was introduced.The results reveal that at a PUC of 0.25,the NPR bolt achieved peak axial force,shear displacement,and peak shear force values that are 2.41,1.88,and 2.13 times greater than those of the PR bolt,respectively.Shear performance was optimized at a prestress level of 100 kN,with energy absorption reaching 47.1 kJ,which is 2.8 times that of the PR bolt.Furthermore,the necking ratio was significantly reduced,indicating more distributed plastic deformation and delayed failure.Field applications verified the superior performance,resulting in a 27.4%reduction in roof settlement and enhanced structural integrity.These findings confirm that NPR bolts possess excellent shear resistance,energy absorption,and deformation adaptability,and optimizing prestress significantly enhances their support performance,providing a strong basis for geotechnical engineering applications.
基金support from the Taishan Scholars Program,Key Research Program of Frontier Sciences,Chinese Academy of Sciences(CAS),Grant No.ZDBS-LY-DQC022Open Research Fund of State Key Laboratory of Geomechanics and Geotechnical Engineering Safety,Grant No.SKLGME023003.
文摘High rock temperature is a great challenge frequently encountered during subsurface resource recovery and deep underground space utilization,and it is still unclear how the granitic rock responds to realtime high temperature upon shear loading.To better understand the shear fracture behavior and underlying processes of intact granite exposed to thermal-mechanical coupling loading,direct shear tests were conducted utilizing a newly built testing apparatus at varied normal stresses and high temperatures.Influencesof different temperatures and different heating methods(real-time heating and thermal treatment)on the shear mechanical behavior were compared and discussed.Results indicate that shear stress fluctuationswith some small stress drops occur as shear stress is approaching the peak strength under real-time heating,accompanied by more and earlier AE signal uprushes.This suggests that greater cracking events occur earlier during real-time heating than after thermal treatment,resulting in a lower peak shear strength.Furthermore,the peak shear strength,post-peak stress drop,and cohesion rise from room temperature(RT)to 200℃(the peak strength increases by 8%,5.8%,and 9.9%under normal stress of 5 MPa,15 MPa,and 20 MPa,correspondingly),and subsequently decline from 200℃to 400℃.Temperature has a limited impact on shear stiffness from RT to 200℃,but significantlyreduces it from 200℃to 400℃,with drops of 15%,7.9%,and 10%under normal stress of 5 MPa,15 MPa,and 20 MPa,respectively.Moreover,the shear strength and stiffness under real-time heating are lower than those for the thermally treated specimens.The strengthening of intact granite below 200℃upon shear is associated with loss of water and a more compacted structure,while the weakening effect of temperature on shear strength from 200℃to 400℃is due to the new thermal cracks and less brittle and stiff of minerals.
基金supported by the National Natural Science Foundation of China(Grant No.42407199)Heilongjiang Provincial Natural Science Foundation of China(Grant No.PL2024D003)the Fundamental Research Funds for the Central Universities(Grant No.2572023CT17).
文摘A novel method that combines reinforced enzyme-induced carbonate precipitation(REICP)was proposed to improve the mechanical properties of dispersive soil.Dispersive soils,which are highly susceptible to erosion caused by rainfall or seepage,pose significantenvironmental challenges.It is essential to focus on modifying dispersive soil using environmentally friendly methods.This study investigated the cohesion,internal friction angle,permeability,hydrostability test,and microstructure of dispersive soil treated with enzyme-induced carbonate precipitation(EICP)-MgCl2-xanthan gum(REICP),using statistical analysis.A series of laboratory experiments was conducted,including direct shear tests,permeability experiments,mud ball tests,simulated rainfall tests,Fourier transform infrared spectroscopy(FTIR),X-ray diffraction(XRD),and scanning electron microscopy(SEM).The results showed that the combined treatment significantly enhanced the mechanical properties of dispersive soil.At the optimal ratio,cohesion increased by a factor of 2,and the permeability coefficientdecreased by approximately 1.7×10^(7)times.Additionally,the strength parameters gradually increased with curing time.Microstructural analyses indicated that calcite precipitation,pore filling,and ionic redistribution significantlyimproved the mechanical properties and hydrostability of the soil.Statistical analyses showed that EICP materials and xanthan gum increased soil cohesion,while magnesium chloride enhanced the internal friction angle and reduced porosity.This study integrates mechanical testing,statistical analysis,and microstructural evaluation to propose a sustainable and environmentally friendly method for improving dispersive soils.This approach reduces the use of chemical modifiers,minimizes environmental impacts,and demonstrates application potential in the stabilization of dispersive soils.
基金jointly supported by the National Natural Science Foundation of China[grant numbers U2342202,42175005,and 42175016]the Qing Lan Project[grant number R2023Q06]。
文摘This study investigates the width of the secondary eyewall(SE)immediately following its formation in tropical cyclones with surface environmental winds aligned and counter-aligned with environmental vertical wind shear(VWS),using idealized numerical experiments.Results reveal that the SE develops greater radial extent when surface winds align with VWS compared to counter-aligned conditions.In alignment configurations,shear-enhanced surface winds on the right flank amplify surface enthalpy fluxes,thereby elevating boundary-layer entropy within the downshear outer-core region.Subsequently,more vigorous outer rainbands develop,inducing marked acceleration of tangential winds in the outer core preceding SE formation.The resultant radial expansion of supergradient winds near the boundary-layer top triggers widespread convective activity immediately beyond the inner core.Progressive axisymmetrization of this convective forcing ultimately generates an expansive SE structure.
基金support from the Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(Grant No.KYCX24_2822)the Graduate Innovation Program of China University of Mining and Technology(Grant No.2024WLKXJ205)the National Natural Science Foundation of China(Grant No.52474157).
文摘Excavation causes stress redistribution and affects the stress path during the shearing process of rock.The shear strength of rock varies under different stress paths,and the presence of defects reduces the shear strength.To further investigate this phenomenon,this study investigates the shear behaviour of rocks with different shear surface integrities under the influenceof different stress paths through laboratory tests and numerical simulations.The results indicate that the shear strength depends on the stress path and a decrease in the shear surface integrity reduces the degree of dependence.The cohesion and friction angle of the Mohr‒Coulomb criterion decrease with weakening of the shear surface integrity.For different stress paths,the direct shear strength is always greater than that of other shear stress paths.The pattern of changes in the acoustic emission count and cumulative count indirectly reflectsthe above findings.Numerical simulations further indicate that the different principal stress states and normal suppression effects during the shearing process lead to changes in the factors of crack propagation,resulting in different mechanical behaviours under various stress paths.For rocks with different integrity levels,the main reason for the different path dependences of shear strength is that the size of the area affected by shear is different.Shear failure will concentrate on the shear plane when the normal inhibition effect is greater.This study explores the mechanism of rock shear behaviour,providing a theoretical basis for establishing more accurate constitutive models and strength criteria.
基金supported by the National Natural Science Foundation of China(Grant No.52179128)the Sand Hazards and Opportunities for Resilience,Energy,and Sustainability(SHORES)Center,funded by Tamkeen under the NYUAD Research Institute Award CG013.
文摘We present a novel approach for calculating the energy budget components during the progressive failure process in cohesive-frictional geomaterials.The energy supplied through external loading can be either stored as elastic strain energy and plastic energy storage or dissipated through damage growth and irreversible plastic deformation mechanisms.Analytical functions describing energy budget components are derived based on a thermodynamic formulation in geomaterials fracture.The thermodynamically consistent derivation leads to a non-local ductile damage model,which is solved numerically in a non-linear finite element framework.The proposed model captures geomaterial fractures in three benchmark examples,including tensile and biaxial-compressive shear scenarios and slope stability analysis.The aspects of shear fracture propagation and energy budget mechanisms are elaborately investigated,considering different material properties and stochastic distributions.The numerical results are validated against existing experimental data and other analytical methods.The model provides a physics-based understanding of energy budget in geomaterials fracture,leading to advances in ground improvement and other geotechnical supporting systems.
基金supported by the National Natural Science Foundation of China(82427808,61875085)the Jiangsu Provincial University Natural Science Foundation(25KJB413004)+1 种基金the Nanjing Health Science and Technology Development Foundation(ZKX24043)the Fundamental Research Funds for the Central Universities(NJ2024029).
文摘Microwave ablation(MWA)is a minimally invasive technique for treating hepatic tumors,necessitating precise monitoring to ensure treatment efficacy and minimize damage to surrounding tissues.This study explores the potential of photoacoustic imaging(PAI)in monitoring MWA by examining ex vivo porcine liver tissues.In this study,a comprehensive analysis of photoacoustic signals was performed to compare the main lobe width(MLW)between ablated and normal regions in porcine liver tissue.Histological staining with succinate dehydrogenase(SDH)and shear wave elastography(SWE)were employed to validate the changes in tissue elasticity after ablation.The analysis demonstrated a notable reduction in the MLW of the average A-lines in ablated tissues compared to nonablated regions(p<0.01).This reduction,attributed to increased tissue density and enhanced elasticity,indicates accelerated sound propagation in thermally ablated areas,which then serves as a critical parameter for mapping tissue characteristics.The reconstruction of the MLW distribution successfully delineated the ablated regions,and was consistent with the results of SDH staining and SWE.In addition,MLW-based imaging exhibited higher spatial resolution compared to SWE.Incorporating MLW analysis into PAI may be a promising strategy to improve the accuracy and effectiveness of MWA monitoring in clinical settings.
文摘Artificial intelligence(AI)is revolutionizing medical imaging,particularly in chronic liver diseases assessment.AI technologies,including machine learning and deep learning,are increasingly integrated with multiparametric ultrasound(US)techniques to provide more accurate,objective,and non-invasive evaluations of liver fibrosis and steatosis.Analyzing large datasets from US images,AI enhances diagnostic precision,enabling better quantification of liver stiffness and fat content,which are essential for diagnosing and staging liver fibrosis and steatosis.Combining advanced US modalities,such as elastography and doppler imaging with AI,has demonstrated improved sensitivity in identifying different stages of liver disease and distinguishing various degrees of steatotic liver.These advancements also contribute to greater reproducibility and reduced operator dependency,addressing some of the limitations of traditional methods.The clinical implications of AI in liver disease are vast,ranging from early detection to predicting disease progression and evaluating treatment response.Despite these promising developments,challenges such as the need for large-scale datasets,algorithm transparency,and clinical validation remain.The aim of this review is to explore the current applications and future potential of AI in liver fibrosis and steatosis assessment using multiparametric US,highlighting the technological advances and clinical relevance of this emerging field.
基金supported by the National Natural Science Foundation of China (Nos.42422705,42207175,42177117 and 42577170)the Ningbo Youth Leading Talent Project (No.2024QL051)+1 种基金the Chinese Academy of Engineering Science and Technology Strategy Consulting Project (No.2025-XZ-57)the Central Government Funding Program for Guiding Local Science and Technology Development (No.2025ZY01028)。
文摘Rock mass stability is significantly influenced by the heterogeneity of rock joint roughness and shear strength.While modern technology facilitates assessing roughness heterogeneity,evaluating shear strength heterogeneity remains challenging.To address this,this study first captures the morphology of large-scale(1000 mm × 1000 mm) slate and granite joints via 3D laser scanning.Analysis of these surfaces and corresponding push/pull tests on carved specimens revealed a potential correlation between the heterogeneity of roughness and shear strength.A comparative evaluation of five statistical metrics identified information entropy(Hs) as the most robust indicator for quantifying rock joint heterogeneity.Further analysis using Hsreveals that the heterogeneity is anisotropic and,critically,that shear strength heterogeneity is governed not only by roughness heterogeneity but is also significantly influenced by the mean roughness value,normal stress,and intact rock tensile strength.Consequently,a simple comparison of roughness Hsvalues is insufficient for reliably comparing shear strength heterogeneity.To overcome this limitation,a theoretical framework is developed to explicitly map fundamental roughness statistics(mean and heterogeneity) to shear strength heterogeneity.This framework culminates in a practical workflow that allows for the rapid,field-based assessment of shear strength heterogeneity using readily obtainable rock joint roughness data.
基金supported by the High-end Foreign Expert Introduction Program(Grant No.G2022165004L)the Sichuan Transportation Science and Technology Project(Grant No.2018-ZL-01)China Railway 20th Bureau Science and Technology Project(Grant No.YF1900SD07B).
文摘Root-inspired anchorage systems in the field of bio-inspired geotechnics are renowned for enhancing the pullout capacity of traditional geotechnical anchorage systems by simulating the morphology and architecture of plant root systems.However,limited studies have explored their practical applications,particularly in improving slope stability.To fill this gap,this study investigates the reinforcement effect of root-inspired anchors on slope stabilization using transparent soil modeling and 3D-printed anchors,and examines the impact of anchor branching patterns(i.e.branching numbers,branching angle,and branching nodes)on slope bearing capacity,shear band evolution,and temporal and spatial variation of slope deformation.The results show that peak slope bearing capacity increases with branching numbers and branching angles,correlating with the envelope area of the curved shear band.Upper anchors result in step-like deflections in the shear band near the trailing edge,while lower anchors convert the upward concave shear band into an upward convex one,thus increasing the slope bearing capacity.Slope deformation is minimized with intermediate branching parameters,such as a branching number of 4 and a branching angle of 45°.The anchor reinforcement mechanisms,i.e.anchor rod shear resistance,interface friction,anchor pullout capacity,and plate tightening effects,are comprehensively discussed,and the installation effects resulting from compromise slope modeling are identified as the contributors.These findings shed light on the failure process of root-inspired anchors reinforced slopes and provide a preliminary reference for potential applications,especially for the tradeoff between anchor branching,slope deformation,and slope stability.
基金sponsored by National Natural Science Foundation of China(Nos.52305146 and 52275165)Natural Science Foundation of Chongqing,China(No.cstb2022nscqmsx1290)+1 种基金the financial support from the Major Special Project for Technological Innovation and Application Development of Chongqing(No.CSTB2024TIAD-STX0015)the Key Laboratory Project of Shaanxi Province(No.2025SYS-SYSZD-064)。
文摘This study introduces electromagnetic dynamic self-piercing riveting(ED-SPR),an innovative technique that integrates electromagnetic riveting principles with static self-piercing riveting(S-SPR)for highperformance structural joints.A dedicated methodology and experimental apparatus for ED-SPR were systematically designed and validated.Quantitative comparative analyses between ED-SPR and S-SPR were conducted on three critical material combinations:CFRP/Al,low-strength steel HC340 LA/Al,and high-strength steel DP590/Al.Key findings demonstrate that the electromagnetic-driven process reduces installation resistance by 60%and achieves a 30%larger interlock distance at the joint base compared to S-SPR.These quantitative advantages directly contribute to an approximately 30%increase in load-bearing capacity and superior damage tolerance in ED-SPR joints,as evidenced by tensile-shear testing of single-lap joints.Furthermore,distinct failure modes were observed:ED-SPR joints exhibited top plate pull-out failure in CFRP/Al and DP590/Al configurations,contrasting with the predominant rivet pull-out failure in S-SPR counterparts.Surface morphology and damage evolution were characterized via scanning electron microscopy(SEM)on post-assembly and tensile-failed specimens.The study establishes a foundation for optimizing electromagnetic-driven riveting parameters to mitigate CFRP delamination and further enhance joint reliability in vehicle body and aircraft fuselage structures.
基金support from the National Key Research and Development Program of China(Grant No.2022YFE0137200)supported by the Taishan Scholars Program and Open Research Fund of State Key Laboratory of Geomechanics and Geotechnical Engineering Safety(Grant No.SKLGME023003).
文摘High geo-stress and high temperature in deep rock engineering increase the possibility of engineering and geological disasters in discontinuous rocks.However,the influence of thermomechanical coupling on the shear behavior and damage evolution of prefractured granite remains immature.In this context,true triaxial laboratory tests and discrete element method simulations under different confining pressures(σ3=3 MPa,σ2=4 MPa,andσ3=80 MPa,σ2=100 MPa)and temperatures(25℃-500℃)were carried out on rough granite fractures with two different orientations.Results indicate that high temperature and high confining pressure increase the peak strength of the prefractured specimen,leading to more microcracks in the host rock and more gouges between the surfaces.Thermal strengthening at low temperatures(<300℃)and residual stick-slip only occur under a greater confining pressure for prefractured specimens.High confining pressure suppresses generation of the thermal microcracks in the heating stage.Cracks first initiate in the asperities on the fracture surfaces,and then propagate into the rock matrix during the mechanical loading stage.In addition,prefractured granite with a larger fracture angle is characterized by smaller peak and residual strength,faster residual slip,fewer new cracks on the specimen surface,and a more pronounced thermal strengthening effect on peak strength.The slip tendency analysis indicates that a higher maximum principal stress(s1)and a large fracture angle(45°-75°)generally result in a higher potential for fracture slip or activation.This study will contribute to a better understanding of the fracture shear mechanism under true triaxial thermomechanical coupling conditions and provides new insights into the stability evaluation of deep dynamic geological hazards.