BACKGROUND Cervical degenerative disc(CDD)disease is a common type of spondylosis.Although anterior cervical discectomy and fusion(ACDF)is the preferred treatment for CDD disease,internal fixation with a titanium plat...BACKGROUND Cervical degenerative disc(CDD)disease is a common type of spondylosis.Although anterior cervical discectomy and fusion(ACDF)is the preferred treatment for CDD disease,internal fixation with a titanium plate may cause various complications.The invention of the ACDF with a self-locking fusion cage(ROI-C)has effectively decreased the incidence of postoperative complications.AIM To observe the outcomes of CDD disease treated by ACDF with a ROI-C.METHODS Ninety patients with CDD disease treated at our hospital from March 2019 to March 2021 were included.They were divided into two groups(control group and observation group,n=45 in each)using a random number table.Patients in the control group received ACDF plus internal fixation with a titanium plate.Those in the observation group received ACDF+ROI-C placement.The two groups of patients were compared in terms of surgical parameters,pain,cervical spine function,range of motion,and complications.RESULTS The two groups of patients showed no significant differences in surgical time,blood loss,drainage volume,and length of hospital stay(P>0.05).No significant differences in the visual analogue scale(VAS),Japanese Orthopedic Association(JOA),and neck disability index(NDI)scores were observed between the two groups before surgery(P>0.05).The VAS and NDI scores in the observation group were considerably lower than those in the control group after surgery;however,the JOA scores in the observation group were significantly higher than those in the control group(P<0.05).No significant differences were observed in cervical disc height and the range of motion of the superior or inferior adjacent vertebrae between the two groups before surgery(P>0.05).The disc height in the observation group was larger than that in the control group after surgery.The range of motion of both the superior and inferior adjacent vertebrae was significantly smaller in the observation group than in the control group(P<0.05).The incidence of complications was only 2.22% in the observation group compared to 15.56% in the control group,and the difference was statistically significant(P<0.05).CONCLUSION Cervical spine function restoration was better with ROI-C with internal fixation in ACDF than with conventional titanium plates in ACDF for CDD disease.展开更多
A concept is introduced for initiating the design study of a special class of tokamak,which has a magnetic confinement configuration intermediate between contemporary advanced tokamak and the recently established sphe...A concept is introduced for initiating the design study of a special class of tokamak,which has a magnetic confinement configuration intermediate between contemporary advanced tokamak and the recently established spherical torus (ST,also well known by the name "spherical tokamak").The leading design parameter in the present proposal is a dimensionless geometrical parameter, the machine aspect ratio A=R 0/a 0= 2.0,where the parameters a 0 and R 0 denote,respectively,the plasma (equatorial) minor radius and the plasma major radius.The aim of this choice is to technologically and experimentally go beyond the aspect ratio frontier (R 0/a 0≈2.5) of present day tokamaks and enter a broad unexplored domain existing on the (a 0,R 0) parameter space in current international tokamak database,between the data region already moderately well covered by the advanced conventional tokamaks and the data region planned to be covered by STs.Plasma minor radius a 0 has been chosen to be the second basic design parameter, and consequently,the plasma major radius R 0 is regarded as a dependent design parameter.In the present concept,a nominal plasma minor radius a 0=1.2m is adopted to be the principal design value,and smaller values of a 0 can be used for auxiliary design purposes,to establish extensive database linkage with existing tokamaks.Plasma minor radius can also be adjusted by mechanical and/or electromagnetic means to smaller values during experiments,for making suitable data linkages to existing machines with higher aspect ratios and smaller plasma minor radii.The basic design parameters proposed enable the adaptation of several confinement techniques recently developed by STs,and thereby a specially arranged central bore region inside the envisioned tokamak torus,with retrieved space in the direction of plasma minor radius,will be available for technological adjustments and maneuverings to facilitate implementation of engineering instrumentation and real time high field side radiation and particle diagnostics,especially for high field side edge physics and plasma surface interaction studies.展开更多
Because of their economy and applicability,high-power thyristor devices are widely used in the power supply systems for large fusion devices.When high-dose neutrons produced by deuterium–tritium(D–T)fusion reactions...Because of their economy and applicability,high-power thyristor devices are widely used in the power supply systems for large fusion devices.When high-dose neutrons produced by deuterium–tritium(D–T)fusion reactions are irradiated on a thyristor device for a long time,the electrical characteristics of the device change,which may eventually cause irreversible damage.In this study,with the thyristor switch of the commutation circuit in the quench protection system(QPS)of a fusion device as the study object,the relationship between the internal physical structure and external electrical parameters of the irradiated thyristor is established.Subsequently,a series of targeted thyristor physical simulations and neutron irradiation experiments are conducted to verify the accuracy of the theoretical analysis.In addition,the effect of irradiated thyristor electrical characteristic changes on the entire QPS is studied by accurate simulation,providing valuable guidelines for the maintenance and renovation of the QPS.展开更多
Magnetized target fusion is an alternative method to fulfill the goal of controlled fusion, which combines advan- tages of both magnetic confinement fusion and inertial confinement fusion since its parameter space lie...Magnetized target fusion is an alternative method to fulfill the goal of controlled fusion, which combines advan- tages of both magnetic confinement fusion and inertial confinement fusion since its parameter space lies between the two traditional ways. Field reversed configuration （FFtC） is a good candidate of magnetized targets due to its translatable, compressible, high /3 and high energy density properties. Dynamic formation process of high density FFtC is observed on the YingGuang 1 device for the first time in China. The evolution of a magnetic field is detected with magnetic probes, and the compression process can be clearly seen from images taken with a high-speed multi-frame CCD camera. The process is also studied with two-dimensional magneto hydrodynamic code MPF-2D theoretically, and the results agree well with the experiment. Combining the experimental data and the theoretical analysis, the length of the formed FRC is about 39 cm, the diameter is about 2-2. 7cm, the average density is 1.3× 1016 cm-3, and the average temperature is 137eV.展开更多
Interspinous posterior device(IPD) is a term used to identify a relatively recent group of implants used to treat lumbar spinal degenerative disease. This kind of device is classified as part of the group of the dynam...Interspinous posterior device(IPD) is a term used to identify a relatively recent group of implants used to treat lumbar spinal degenerative disease. This kind of device is classified as part of the group of the dynamic stabilization systems of the spine. The concept of dynamic stabilization has been replaced by that of dynamic neutralization of hypermobility, with the intention of clarifying that the primary aim of this kind of system is not the preservation of the movement, but the dynamic neutralization of the segmental hypermobility which is at the root of the pathological condition. The indications for the implantation of an IPD are spinal stenosis and neurogenic claudication, assuming that its function is the enlargement of the neural foramen and the decompression of the roots forming the cauda equina in the central part of the vertebral canal. In the last 10 years, use of these implants has been very common but to date, no long-term clinical follow-up regarding clinical and radiological aspects are available. The high rate of reoperation, recurrence of symptoms and progression of degenerative changes is evident in the literature. If these devices are effectively a miracle cure for lumbar spinal stenosis, why do the utilization and implantation of IPD remain extremely controversial and should they be investigated further? Excluding theproblems related to the high cost of the device, the main problem remains the pathological substrate on which the device is explicit in its action: the degenerative pathology of the spine.展开更多
There is no clear consensus regarding how cells respond to hydrostatic pressure. This is largely attributable to the high heterogeneity among cell types and the diverse custom-made devices used in previous studies. Th...There is no clear consensus regarding how cells respond to hydrostatic pressure. This is largely attributable to the high heterogeneity among cell types and the diverse custom-made devices used in previous studies. The aim of this work was to develop a facile device that could mimic various pressure environments and then delineate the cellular response to pressure stimulus. The device described here achieved both stable and periodic pressurization without oxygen deprivation. The biological utility of the device was assessed using human umbilical vein endothelial cells. We found more stereoscopic nuclear morphology and re-distribution of lamin A/C under high hydrostatic pressure compared to control cells. Mass spectrometry-based proteomics analysis showed significant changes in mitochondria-related pathways. Western blot analysis confirmed that high hydrostatic pressure induced a tendency toward mitochondrial fusion. Increased mitochondrial activity was observed as well. In conclusion, this device can be readily applied in biological research and extend our understanding of cellular mechano-sensation and the associated changes in mitochondrial behaviors.展开更多
This paper proposes a novel clamping device for leveling equipment mounted on offshore oil platform jacket,which solves the problem of leveling equipment clamping lifting force of more than 2000 tons.The main features...This paper proposes a novel clamping device for leveling equipment mounted on offshore oil platform jacket,which solves the problem of leveling equipment clamping lifting force of more than 2000 tons.The main features are that lifting force transmits to clamp claw through wedge force amplifier,embed the teeth of claw into the pile,and the embedded depth increases with the lifting force,resulting in a gravitational self-locking function.This theoretical model of clamping device was established,and the force and material characteristic were analyzed,and the feasibility of the theoretical model was verified by thin shell elastic-plastic stability theory and thin-walled structures theory.An experimental prototype of clamping device was produced to test gravity self-locking function and bearable leveling force.Compared with the theoretical model and the experimental results,it proved that the embedded clamping devices have gravitational self-locking function and can meet the need of actual leveling equipment.展开更多
Loss-cone instabilities are studied for linear fusion devices. The gyro-kinetic equation for such a configuration is rigorously constructed in terms of action-angle variables by making use of canonical transformation....Loss-cone instabilities are studied for linear fusion devices. The gyro-kinetic equation for such a configuration is rigorously constructed in terms of action-angle variables by making use of canonical transformation. The dispersion relation, including for the first time, finite bounce frequency is obtained and numerically solved. The loss-cone modes are found near ion-cyclotron frequency. The growth rates are greatly reduced and approaching zero with increasing beta value. The results suggest that loss-cone instabilities are unlikely to be threatening to linear fusion devices since a new longitudinal invariant is found and gives a constraint which helps confinement.展开更多
A system for classifying four basic table tennis strokes using wearable devices and deep learning networks is proposed in this study.The wearable device consisted of a six-axis sensor,Raspberry Pi 3,and a power bank.M...A system for classifying four basic table tennis strokes using wearable devices and deep learning networks is proposed in this study.The wearable device consisted of a six-axis sensor,Raspberry Pi 3,and a power bank.Multiple kernel sizes were used in convolutional neural network(CNN)to evaluate their performance for extracting features.Moreover,a multiscale CNN with two kernel sizes was used to perform feature fusion at different scales in a concatenated manner.The CNN achieved recognition of the four table tennis strokes.Experimental data were obtained from20 research participants who wore sensors on the back of their hands while performing the four table tennis strokes in a laboratory environment.The data were collected to verify the performance of the proposed models for wearable devices.Finally,the sensor and multi-scale CNN designed in this study achieved accuracy and F1 scores of 99.58%and 99.16%,respectively,for the four strokes.The accuracy for five-fold cross validation was 99.87%.This result also shows that the multi-scale convolutional neural network has better robustness after fivefold cross validation.展开更多
针对结构振动试验中仅能获取应力均方根(root mean square,RMS)值而缺失功率谱密度(power spectral density,PSD)数据的问题,提出一种试验-仿真融合的振动应力PSD重构方法。该方法通过模态试验修正有限元模型,结合实测模态阻尼与RMS约...针对结构振动试验中仅能获取应力均方根(root mean square,RMS)值而缺失功率谱密度(power spectral density,PSD)数据的问题,提出一种试验-仿真融合的振动应力PSD重构方法。该方法通过模态试验修正有限元模型,结合实测模态阻尼与RMS约束优化,实现高精度PSD重构。基于航空组合件在宽带随机振动(20~1000 Hz)下的试验验证表明:重构PSD与试验PSD在谱型(主频误差<2%、幅值误差<5%)和RMS值上均高度吻合;采用24种载荷谱模型的疲劳寿命预测最大误差为10.2%,其中18种模型误差低于3.28%。以某机载液压驱动装置为例,验证了该方法在结构优化中的实用性,显著减少实物试验迭代次数。展开更多
文摘BACKGROUND Cervical degenerative disc(CDD)disease is a common type of spondylosis.Although anterior cervical discectomy and fusion(ACDF)is the preferred treatment for CDD disease,internal fixation with a titanium plate may cause various complications.The invention of the ACDF with a self-locking fusion cage(ROI-C)has effectively decreased the incidence of postoperative complications.AIM To observe the outcomes of CDD disease treated by ACDF with a ROI-C.METHODS Ninety patients with CDD disease treated at our hospital from March 2019 to March 2021 were included.They were divided into two groups(control group and observation group,n=45 in each)using a random number table.Patients in the control group received ACDF plus internal fixation with a titanium plate.Those in the observation group received ACDF+ROI-C placement.The two groups of patients were compared in terms of surgical parameters,pain,cervical spine function,range of motion,and complications.RESULTS The two groups of patients showed no significant differences in surgical time,blood loss,drainage volume,and length of hospital stay(P>0.05).No significant differences in the visual analogue scale(VAS),Japanese Orthopedic Association(JOA),and neck disability index(NDI)scores were observed between the two groups before surgery(P>0.05).The VAS and NDI scores in the observation group were considerably lower than those in the control group after surgery;however,the JOA scores in the observation group were significantly higher than those in the control group(P<0.05).No significant differences were observed in cervical disc height and the range of motion of the superior or inferior adjacent vertebrae between the two groups before surgery(P>0.05).The disc height in the observation group was larger than that in the control group after surgery.The range of motion of both the superior and inferior adjacent vertebrae was significantly smaller in the observation group than in the control group(P<0.05).The incidence of complications was only 2.22% in the observation group compared to 15.56% in the control group,and the difference was statistically significant(P<0.05).CONCLUSION Cervical spine function restoration was better with ROI-C with internal fixation in ACDF than with conventional titanium plates in ACDF for CDD disease.
文摘A concept is introduced for initiating the design study of a special class of tokamak,which has a magnetic confinement configuration intermediate between contemporary advanced tokamak and the recently established spherical torus (ST,also well known by the name "spherical tokamak").The leading design parameter in the present proposal is a dimensionless geometrical parameter, the machine aspect ratio A=R 0/a 0= 2.0,where the parameters a 0 and R 0 denote,respectively,the plasma (equatorial) minor radius and the plasma major radius.The aim of this choice is to technologically and experimentally go beyond the aspect ratio frontier (R 0/a 0≈2.5) of present day tokamaks and enter a broad unexplored domain existing on the (a 0,R 0) parameter space in current international tokamak database,between the data region already moderately well covered by the advanced conventional tokamaks and the data region planned to be covered by STs.Plasma minor radius a 0 has been chosen to be the second basic design parameter, and consequently,the plasma major radius R 0 is regarded as a dependent design parameter.In the present concept,a nominal plasma minor radius a 0=1.2m is adopted to be the principal design value,and smaller values of a 0 can be used for auxiliary design purposes,to establish extensive database linkage with existing tokamaks.Plasma minor radius can also be adjusted by mechanical and/or electromagnetic means to smaller values during experiments,for making suitable data linkages to existing machines with higher aspect ratios and smaller plasma minor radii.The basic design parameters proposed enable the adaptation of several confinement techniques recently developed by STs,and thereby a specially arranged central bore region inside the envisioned tokamak torus,with retrieved space in the direction of plasma minor radius,will be available for technological adjustments and maneuverings to facilitate implementation of engineering instrumentation and real time high field side radiation and particle diagnostics,especially for high field side edge physics and plasma surface interaction studies.
基金supported by the Fundamental Research Funds for the Central University(No.JZ2023HGTA0182)Comprehensive Research Facility for Fusion Technology Program of China(No.2018-000052-73-01-001228)。
文摘Because of their economy and applicability,high-power thyristor devices are widely used in the power supply systems for large fusion devices.When high-dose neutrons produced by deuterium–tritium(D–T)fusion reactions are irradiated on a thyristor device for a long time,the electrical characteristics of the device change,which may eventually cause irreversible damage.In this study,with the thyristor switch of the commutation circuit in the quench protection system(QPS)of a fusion device as the study object,the relationship between the internal physical structure and external electrical parameters of the irradiated thyristor is established.Subsequently,a series of targeted thyristor physical simulations and neutron irradiation experiments are conducted to verify the accuracy of the theoretical analysis.In addition,the effect of irradiated thyristor electrical characteristic changes on the entire QPS is studied by accurate simulation,providing valuable guidelines for the maintenance and renovation of the QPS.
基金Supported by the Development Foundation of China Academy of Engineering Physics under Grant No 2011B0402009the National Natural Science Foundation of China under Grant Nos 11375163,11575029 and 11175028
文摘Magnetized target fusion is an alternative method to fulfill the goal of controlled fusion, which combines advan- tages of both magnetic confinement fusion and inertial confinement fusion since its parameter space lies between the two traditional ways. Field reversed configuration （FFtC） is a good candidate of magnetized targets due to its translatable, compressible, high /3 and high energy density properties. Dynamic formation process of high density FFtC is observed on the YingGuang 1 device for the first time in China. The evolution of a magnetic field is detected with magnetic probes, and the compression process can be clearly seen from images taken with a high-speed multi-frame CCD camera. The process is also studied with two-dimensional magneto hydrodynamic code MPF-2D theoretically, and the results agree well with the experiment. Combining the experimental data and the theoretical analysis, the length of the formed FRC is about 39 cm, the diameter is about 2-2. 7cm, the average density is 1.3× 1016 cm-3, and the average temperature is 137eV.
文摘Interspinous posterior device(IPD) is a term used to identify a relatively recent group of implants used to treat lumbar spinal degenerative disease. This kind of device is classified as part of the group of the dynamic stabilization systems of the spine. The concept of dynamic stabilization has been replaced by that of dynamic neutralization of hypermobility, with the intention of clarifying that the primary aim of this kind of system is not the preservation of the movement, but the dynamic neutralization of the segmental hypermobility which is at the root of the pathological condition. The indications for the implantation of an IPD are spinal stenosis and neurogenic claudication, assuming that its function is the enlargement of the neural foramen and the decompression of the roots forming the cauda equina in the central part of the vertebral canal. In the last 10 years, use of these implants has been very common but to date, no long-term clinical follow-up regarding clinical and radiological aspects are available. The high rate of reoperation, recurrence of symptoms and progression of degenerative changes is evident in the literature. If these devices are effectively a miracle cure for lumbar spinal stenosis, why do the utilization and implantation of IPD remain extremely controversial and should they be investigated further? Excluding theproblems related to the high cost of the device, the main problem remains the pathological substrate on which the device is explicit in its action: the degenerative pathology of the spine.
基金supported by grants from the National Key R&D Program of China(No.2018YFC1005002)the National Natural Science Foundation of China(Nos.82070482,81772007,21734003 and 51927805)+1 种基金the Shanghai Municipal Science and Technology Major Project(No.2017SHZDZX01)the Shanghai Municipal Education Commission(Innovation Program No.2017-01-07-00-07E00027)。
文摘There is no clear consensus regarding how cells respond to hydrostatic pressure. This is largely attributable to the high heterogeneity among cell types and the diverse custom-made devices used in previous studies. The aim of this work was to develop a facile device that could mimic various pressure environments and then delineate the cellular response to pressure stimulus. The device described here achieved both stable and periodic pressurization without oxygen deprivation. The biological utility of the device was assessed using human umbilical vein endothelial cells. We found more stereoscopic nuclear morphology and re-distribution of lamin A/C under high hydrostatic pressure compared to control cells. Mass spectrometry-based proteomics analysis showed significant changes in mitochondria-related pathways. Western blot analysis confirmed that high hydrostatic pressure induced a tendency toward mitochondrial fusion. Increased mitochondrial activity was observed as well. In conclusion, this device can be readily applied in biological research and extend our understanding of cellular mechano-sensation and the associated changes in mitochondrial behaviors.
文摘This paper proposes a novel clamping device for leveling equipment mounted on offshore oil platform jacket,which solves the problem of leveling equipment clamping lifting force of more than 2000 tons.The main features are that lifting force transmits to clamp claw through wedge force amplifier,embed the teeth of claw into the pile,and the embedded depth increases with the lifting force,resulting in a gravitational self-locking function.This theoretical model of clamping device was established,and the force and material characteristic were analyzed,and the feasibility of the theoretical model was verified by thin shell elastic-plastic stability theory and thin-walled structures theory.An experimental prototype of clamping device was produced to test gravity self-locking function and bearable leveling force.Compared with the theoretical model and the experimental results,it proved that the embedded clamping devices have gravitational self-locking function and can meet the need of actual leveling equipment.
基金supported by the Natural Science Foundation for Young Scientists of China (No. 11605143)National Natural Science Foundation of China (Nos. 11575055,11261140327,11005035,11205053)+3 种基金the project,Plasma Confinement in the Advanced Magnetic Mirror (WX-2015-01-01)the Open Research Subject of the Key Laboratory of Advanced Computation in Xihua University (Nos. szjj2017-011 and szjj2017-012)the Young Scholarship Plan of Xihua University (No. 0220170201)the National Key Research and Development Program of China (No. 2017YFE0300405)
文摘Loss-cone instabilities are studied for linear fusion devices. The gyro-kinetic equation for such a configuration is rigorously constructed in terms of action-angle variables by making use of canonical transformation. The dispersion relation, including for the first time, finite bounce frequency is obtained and numerically solved. The loss-cone modes are found near ion-cyclotron frequency. The growth rates are greatly reduced and approaching zero with increasing beta value. The results suggest that loss-cone instabilities are unlikely to be threatening to linear fusion devices since a new longitudinal invariant is found and gives a constraint which helps confinement.
基金supporting of the Ministry of Science and Technology MOST(Grant No.MOST 108–2221-E-150–022-MY3,MOST 110–2634-F-019–002)the National Taiwan Ocean University,China.
文摘A system for classifying four basic table tennis strokes using wearable devices and deep learning networks is proposed in this study.The wearable device consisted of a six-axis sensor,Raspberry Pi 3,and a power bank.Multiple kernel sizes were used in convolutional neural network(CNN)to evaluate their performance for extracting features.Moreover,a multiscale CNN with two kernel sizes was used to perform feature fusion at different scales in a concatenated manner.The CNN achieved recognition of the four table tennis strokes.Experimental data were obtained from20 research participants who wore sensors on the back of their hands while performing the four table tennis strokes in a laboratory environment.The data were collected to verify the performance of the proposed models for wearable devices.Finally,the sensor and multi-scale CNN designed in this study achieved accuracy and F1 scores of 99.58%and 99.16%,respectively,for the four strokes.The accuracy for five-fold cross validation was 99.87%.This result also shows that the multi-scale convolutional neural network has better robustness after fivefold cross validation.
