We study the optimal precoding for a full-duplex (FD) system, where one FD multi-antenna base station (BS) respectively transmits to and receives from two half-duplex single-antenna mobile users (MUs) on the same time...We study the optimal precoding for a full-duplex (FD) system, where one FD multi-antenna base station (BS) respectively transmits to and receives from two half-duplex single-antenna mobile users (MUs) on the same time slot and frequency band. At the FD BS, the received signal from the desired MU is severely affected by the extremely strong self-interference (SI) from its transmit antennas to the receive antennas. In the presence of residual SI after imperfect SI cancellation, the downlink transmission rate maximization problem subject to a targeted uplink rate is formulated as a non-convex optimization problem to characterize the achievable rate region for the considered system. Considering the case in which the SI channel is strongly correlated, the above problem is transformed into a convex problem by exploiting the rank-one property of the SI channel, which can be solved efficiently. Finally, numerical results validate the effectiveness of the proposed scheme.展开更多
The 3-D beamforming scheme has elite as evolving interest because of its efficiency to empower assorted techniques such as vertical and horizontal domains and emanation beamforming according to subscriber's provis...The 3-D beamforming scheme has elite as evolving interest because of its efficiency to empower assorted techniques such as vertical and horizontal domains and emanation beamforming according to subscriber's provisions. Usually, 3-D beamforming communication is set up on FDD/TDD approach those effects on the performance of spectrum and energy efficiency. Co-frequency and CoTime Full Duplex(CCFD) is an effective solution to improve the spectrum and energy efficiency by transmitting and receiving simultaneously in frequency and time domain. While, CCFD communication often face the self-interference issue when communication occurs, simultaneously. Consequently, in this paper a self-interference elimination by physical feedback channel in CCFD for 3-D Beamforming communication scheme is proposed to improve the over-all system performance in terms of energy and spectrum efficiency. The simulation and analytical outcomes demonstrated that the proposed system is superior than the traditional one.展开更多
To enable simultaneous transmit and receive(STAR)on the same frequency in a densely deployed space with multi-interference sources,this work proposes a digitally-assisted analog selfinterference cancellation method,wh...To enable simultaneous transmit and receive(STAR)on the same frequency in a densely deployed space with multi-interference sources,this work proposes a digitally-assisted analog selfinterference cancellation method,which can acquire reference signals through flexible wired/wireless switching access.Based on this method,the Minimum Mean Square Error algorithm with known channel state information is derived in detail,determining the upper limit of the cancellation performance,and the Adaptive Dithered Linear Search algorithm for real-time engineering cancellation is given.The correctness of theoretical analysis is verified by the practical self-interference channel measured by a vector network analyzer.Furthermore,we have designed and implemented the corresponding multiinterference cancellation prototype with the digitallyassisted structure,capable of handling multiple interferences(up to three)and supporting a large receive bandwidth of 100 MHz as well as a wide frequency coverage from 30 MHz to 3000 MHz.Prototype test results demonstrate that in the presence of three interferences,when the single interference bandwidth is 0.2/2/20 MHz(corresponding to the receive bandwidth of 2/20/100 MHz),the cancellation performance can reach 46/32/22 dB or more.展开更多
The adaptive filtering algorithm with a fixed projection order is unable to adjust its performance in response to changes in the external environment of airborne radars.To overcome this limitation,a new approach is in...The adaptive filtering algorithm with a fixed projection order is unable to adjust its performance in response to changes in the external environment of airborne radars.To overcome this limitation,a new approach is introduced,which is the variable projection order Ekblom norm-promoted adaptive algorithm(VPO-EPAA).The method begins by examining the mean squared deviation(MSD)of the EPAA,deriving a formula for its MSD.Next,it compares the MSD of EPAA at two different projection orders and selects the one that minimizes the MSD as the parameter for the current iteration.Furthermore,the algorithm’s computational complexity is analyzed theoretically.Simulation results from system identification and self-interference cancellation show that the proposed algorithm performs exceptionally well in airborne radar signal self-interference cancellation,even under various noise intensities and types of interference.展开更多
Ischemia–reperfusion injury is a common pathophysiological mechanism in retinal degeneration.PANoptosis is a newly defined integral form of regulated cell death that combines the key features of pyroptosis,apoptosis,...Ischemia–reperfusion injury is a common pathophysiological mechanism in retinal degeneration.PANoptosis is a newly defined integral form of regulated cell death that combines the key features of pyroptosis,apoptosis,and necroptosis.Oligomerization of mitochondrial voltage-dependent anion channel 1 is an important pathological event in regulating cell death in retinal ischemia–reperfusion injury.However,its role in PANoptosis remains largely unknown.In this study,we demonstrated that voltage-dependent anion channel 1 oligomerization-mediated mitochondrial dysfunction was associated with PANoptosis in retinal ischemia–reperfusion injury.Inhibition of voltage-dependent anion channel 1 oligomerization suppressed mitochondrial dysfunction and PANoptosis in retinal cells subjected to ischemia–reperfusion injury.Mechanistically,mitochondria-derived reactive oxygen species played a central role in the voltagedependent anion channel 1-mediated regulation of PANoptosis by promoting PANoptosome assembly.Moreover,inhibiting voltage-dependent anion channel 1 oligomerization protected against PANoptosis in the retinas of rats subjected to ischemia–reperfusion injury.Overall,our findings reveal the critical role of voltage-dependent anion channel 1 oligomerization in regulating PANoptosis in retinal ischemia–reperfusion injury,highlighting voltage-dependent anion channel 1 as a promising therapeutic target.展开更多
Numerous pathological states of the nervous system involve alterations in neuronal excitability and synaptic dysfunction,which depend on the function of ion channels.Due to their critical involvement in health and dis...Numerous pathological states of the nervous system involve alterations in neuronal excitability and synaptic dysfunction,which depend on the function of ion channels.Due to their critical involvement in health and disease,the search for new compounds that modulate these proteins is still relevant.Traditional medicine has long been a rich source of neuroactive compounds.For example,the indigenous Mapuche people have used the leaves and bark of the Drimys winteri tree for centuries to treat various diseases.Consequently,several studies have investigated the biological effects of compounds in Drimys winteri,highlighting sesquiterpenes such asα-humulene,drimenin,polygodial,andα-,β-,γ-eudesmol.However,there is currently no literature review focusing on the ability of these sesquiterpenes to modulate ion channels.This review summarizes the current knowledge about neuroactive compounds found in Drimys winteri,with special emphasis on their direct actions on neuronal ion channels.Several Drimys winteri sesquiterpenes modulate a diverse array of neuronal ion channels,including transient receptor potential channels,gamma-aminobutyric acid A receptors,nicotinic acetylcholine receptors,and voltage-dependent Ca^(2+)and Na^(+)channels.Interestingly,the modulation of these molecular targets by Drimys winteri sesquiterpenes correlates with their therapeutic actions.The promiscuous pharmacological profile of Drimys winteri sesquiterpenes suggests they modulate multiple protein targets in vivo,making them potentially useful for treating complex,multifactorial diseases.Further studies at the molecular level may aid in developing multitargeted drugs with enhanced therapeutic effects.展开更多
With the growing advancement of wireless communication technologies,WiFi-based human sensing has gained increasing attention as a non-intrusive and device-free solution.Among the available signal types,Channel State I...With the growing advancement of wireless communication technologies,WiFi-based human sensing has gained increasing attention as a non-intrusive and device-free solution.Among the available signal types,Channel State Information(CSI)offers fine-grained temporal,frequency,and spatial insights into multipath propagation,making it a crucial data source for human-centric sensing.Recently,the integration of deep learning has significantly improved the robustness and automation of feature extraction from CSI in complex environments.This paper provides a comprehensive review of deep learning-enhanced human sensing based on CSI.We first outline mainstream CSI acquisition tools and their hardware specifications,then provide a detailed discussion of preprocessing methods such as denoising,time–frequency transformation,data segmentation,and augmentation.Subsequently,we categorize deep learning approaches according to sensing tasks—namely detection,localization,and recognition—and highlight representative models across application scenarios.Finally,we examine key challenges including domain generalization,multi-user interference,and limited data availability,and we propose future research directions involving lightweight model deployment,multimodal data fusion,and semantic-level sensing.展开更多
The in-band full-duplex(IBFD)mechanism is of interest in beyond 5 G systems due to its potential to enhance spectral efficiency and reduce delay.To achieve the maximum gain of IBFD systems,the significant self-interfe...The in-band full-duplex(IBFD)mechanism is of interest in beyond 5 G systems due to its potential to enhance spectral efficiency and reduce delay.To achieve the maximum gain of IBFD systems,the significant self-interference(SI)must be efficiently suppressed.The challenges of wideband selfinterference cancellation(SIC)lie in the radio frequency(RF)domain,where the performance will be limited by the hardware.This paper reviews current RF cancellation mechanisms and investigates an efficient mechanism for future wideband systems with minimum complexity.The working principle and implementation details of multi-tap cancellers are first introduced,then an optical domain-based RF canceller is reviewed,and a novel low-cost design is proposed.To minimize the cost and complexity of the canceller,the minimum required number of taps are analyzed.Simulation results show that with the commonly used 12-bits analog-to-digital converter(ADC)at the receiver,the novel optical domain-based canceller can enable efficient SIC in the 3 GPP LTE specifications compatible system within 400 MHz bandwidth.展开更多
Full duplex radio increases the frequency efficiency but its performance is limited by the self-interference （SI）. We first analyze the multiple noises in the full duplex radio system and model such noises as an α ...Full duplex radio increases the frequency efficiency but its performance is limited by the self-interference （SI）. We first analyze the multiple noises in the full duplex radio system and model such noises as an α - stable distribution. Then we formulate a novel non-Gaussian SI problem. Under the maximum correntropy criterion （MCC）, a robust digital non-linear self-interference cancellation algorithm is proposed for the SI channel estimation. A gradient descent based algorithm is derived to search the optimal solution. Simulation results show that the proposed algorithm can achieve a smaller estimation error and a higher pseudo signal to interference plus noise ratio （PSINR） than the well-known least mean square （LMS） algorithm and least square （LS） algorithm.展开更多
In MIMO full duplex system,power amplifier(PA) nonlinearity limits the self-interference(SI) cancellation seriously. Most existing methods need to model and estimate the PA nonlinearity in order to reconstruct the SI,...In MIMO full duplex system,power amplifier(PA) nonlinearity limits the self-interference(SI) cancellation seriously. Most existing methods need to model and estimate the PA nonlinearity in order to reconstruct the SI,however the estimation error caused by the mismatch between the estimated PA model and the actual PA property still impacts the cancellation ability,especially when the transmit power is high. In this paper we propose a polarization oblique projection based self-interference cancellation method which does not need to estimate the PA nonlinearity coefficients. It exploits the polarization state information of the signals which is immune to the PA nonlinearity,and establishes an oblique projection operator to cancel the SI. Numerical results and analysis demonstrate that it can cancel the nonlinear SI effectively. Moreover the signal to interfere plus noise ratio(SINR) and the achievable sum rate do not deteriorate when the transmit power is high. Further,the upper bound of the achievable sum rate can be more than twice that of the half duplex.展开更多
We discuss the physical layer security scheme in the Full-Duplex(FD)MIMO point-to-point two-way communication system with residual self-interference,in which legitimate nodes send confidential information and null spa...We discuss the physical layer security scheme in the Full-Duplex(FD)MIMO point-to-point two-way communication system with residual self-interference,in which legitimate nodes send confidential information and null space Artificial Noise(AN)while receiving information.Because the Channel State Information(CSI)of the eavesdropper is unavailable,we optimize the covariance matrices of the information signal as well as the allocation of the antenna for transmitting and receiving to minimize the signal power consumption under the target rate constraint.As a result,the power of AN is maximized within the limit of total power,so the interception capability of the eavesdropper is suppressed as much as possible.Since self-interference cannot be completely eliminated,the optimization process of one legitimate node depends on the optimization result of the other.By substituting self-interference power in the secrecy rate formula with its average value,the joint optimization process at the two nodes is transformed into two separate and solvable optimization processes.Then,the Water-Filling Algorithm(WFA)and bisection algorithm are used to get the optimal covariance matrices of the signal.Furthermore,we derive the theoretical lower bound of ergodic achievable secrecy rate under rayleigh channels to evaluate the performance of the scheme.The simulation results show that the theoretical derivation is correct,and the actual achievable rate is very close to the target rate,which means that the approximation in the optimization is feasible.The results also show that secrecy transmission can be realized because a considerable secrecy rate can be achieved.展开更多
Adaptive digital self-interference cancellation(ADSIC)is a significant method to suppress self-interference and improve the performance of the linear frequency modulated continuous wave(LFMCW)radar.Due to efficient im...Adaptive digital self-interference cancellation(ADSIC)is a significant method to suppress self-interference and improve the performance of the linear frequency modulated continuous wave(LFMCW)radar.Due to efficient implementation structure,the conventional method based on least mean square(LMS)is widely used,but its performance is not sufficient for LFMCW radar.To achieve a better self-interference cancellation(SIC)result and more optimal radar performance,we present an ADSIC method based on fractional order LMS(FOLMS),which utilizes the multi-path cancellation structure and adaptively updates the weight coefficients of the cancellation system.First,we derive the iterative expression of the weight coefficients by using the fractional order derivative and short-term memory principle.Then,to solve the problem that it is difficult to select the parameters of the proposed method due to the non-stationary characteristics of radar transmitted signals,we construct the performance evaluation model of LFMCW radar,and analyze the relationship between the mean square deviation and the parameters of FOLMS.Finally,the theoretical analysis and simulation results show that the proposed method has a better SIC performance than the conventional methods.展开更多
This paper presents a design scheme of wire-line telephone system using self-interference(SI)cancellation technology in co-frequency co-time full-duplex(CCFD)system to realize absolute secure communication at the phys...This paper presents a design scheme of wire-line telephone system using self-interference(SI)cancellation technology in co-frequency co-time full-duplex(CCFD)system to realize absolute secure communication at the physical layer.This scheme can hide the target signal by skillfully releasing the high-power artificial noise to the whole link at the receiving node,and then make use of the receiver’s knowledge of the SI signal to achieve high dB SI cancellation with the help of analog domain SI cancellation technology in CCFD domain,so that the signal-to-noise ratio(SNR)received by the eavesdropper at any position of the link is far lower than that of the legitimate receiver,so as to realize the absolutely secure communication in the sense of Wyner principle.This paper not only puts forward the specific design scheme of absolutely secure communication telephone,but also analyzes the calculation of security capacity under different eavesdropping positions,different SI cancellation capability and different system parameters according to Shannon theory.展开更多
In this paper,a general scheme in digital self-interference cancellation at baseband for zero-IF full-duplex transceivers is presented. We model the self-interference signals specifically with only the nonlinear disto...In this paper,a general scheme in digital self-interference cancellation at baseband for zero-IF full-duplex transceivers is presented. We model the self-interference signals specifically with only the nonlinear distortion signals falling in receiving band considered. A joint estimation algorithm is proposed for compensating the time delay and frequency offset taking into account the IQ amplitude and phase imbalances from mixers. The memory effect and nonlinear distortion are adaptively estimated by the de-correlated normalized least mean square(DNLMS) algorithm. Numerical simulation results demonstrate that the proposed self-interference cancellation scheme can efficiently compensate the self-interference and outperform the existing traditional solutions.展开更多
Along with the proliferating research interest in semantic communication(Sem Com),joint source channel coding(JSCC)has dominated the attention due to the widely assumed existence in efficiently delivering information ...Along with the proliferating research interest in semantic communication(Sem Com),joint source channel coding(JSCC)has dominated the attention due to the widely assumed existence in efficiently delivering information semantics.Nevertheless,this paper challenges the conventional JSCC paradigm and advocates for adopting separate source channel coding(SSCC)to enjoy a more underlying degree of freedom for optimization.We demonstrate that SSCC,after leveraging the strengths of the Large Language Model(LLM)for source coding and Error Correction Code Transformer(ECCT)complemented for channel coding,offers superior performance over JSCC.Our proposed framework also effectively highlights the compatibility challenges between Sem Com approaches and digital communication systems,particularly concerning the resource costs associated with the transmission of high-precision floating point numbers.Through comprehensive evaluations,we establish that assisted by LLM-based compression and ECCT-enhanced error correction,SSCC remains a viable and effective solution for modern communication systems.In other words,separate source channel coding is still what we need.展开更多
The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central n...The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central nervous system, with sensory stimulation and excitation conduction functions. Astrocytes and microglia belong to the glial cell family, which is the main source of cytokines and represents the main defense system of the central nervous system. Nerve cells undergo neurotransmission or gliotransmission, which regulates neuronal activity via the ion channels, receptors, or transporters expressed on nerve cell membranes. Ion channels, composed of large transmembrane proteins, play crucial roles in maintaining nerve cell homeostasis. These channels are also important for control of the membrane potential and in the secretion of neurotransmitters. A variety of cellular functions and life activities, including functional regulation of the central nervous system, the generation and conduction of nerve excitation, the occurrence of receptor potential, heart pulsation, smooth muscle peristalsis, skeletal muscle contraction, and hormone secretion, are closely related to ion channels associated with passive transmembrane transport. Two types of ion channels in the central nervous system, potassium channels and calcium channels, are closely related to various neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. Accordingly, various drugs that can affect these ion channels have been explored deeply to provide new directions for the treatment of these neurological disorders. In this review, we focus on the functions of potassium and calcium ion channels in different nerve cells and their involvement in neurological disorders such as Parkinson's disease, Alzheimer's disease, depression, epilepsy, autism, and rare disorders. We also describe several clinical drugs that target potassium or calcium channels in nerve cells and could be used to treat these disorders. We concluded that there are few clinical drugs that can improve the pathology these diseases by acting on potassium or calcium ions. Although a few novel ion-channelspecific modulators have been discovered, meaningful therapies have largely not yet been realized. The lack of target-specific drugs, their requirement to cross the blood–brain barrier, and their exact underlying mechanisms all need further attention. This review aims to explain the urgent problems that need research progress and provide comprehensive information aiming to arouse the research community's interest in the development of ion channel-targeting drugs and the identification of new therapeutic targets for that can increase the cure rate of nervous system diseases and reduce the occurrence of adverse reactions in other systems.展开更多
CO_(2)flooding enhanced oil recovery(CO_(2)-EOR)represents a significant technology in the low permeability reservoir.With the fractures and heterogeneity in low permeability reservoirs,CO_(2)-EOR is susceptible to pe...CO_(2)flooding enhanced oil recovery(CO_(2)-EOR)represents a significant technology in the low permeability reservoir.With the fractures and heterogeneity in low permeability reservoirs,CO_(2)-EOR is susceptible to pessimistic gas channeling.Consequently,there is a need to develop conformance control materials that can be used in CO_(2)-EOR.Herein,to address the challenges of low strength and poor stability of polymer gel in high temperature and low permeability reservoirs,a new organic/metal ion composite crosslinking polymer gel(AR-Gel)is reported,which is formed by low hydrolysis and medium to high molecular weight polymer(CX-305),organic crosslinking agent(phenolic resin),and aluminium citrate(AI(Ⅲ)).The crosslinking of AI(Ⅲ)with carboxyl group and organic/metal ion double crosslinking can construct a more complex and stable polymer gel structure on the basis of traditional chemical crosslinking,to cope with the harsh conditions such as high temperature.The structure-activity relationship of AR-Gel was revealed by rheology behavior and micro-morphology.The applicability of AR-Gel in reservoir was investigated,as was its strength and stability in supercritical CO_(2).The anti-gas channeling and enhanced oil recovery of AR-Gel were investigated using low permeability fractured cores,and the field process parameters were provided.The gel can be used to meet supercritical CO_(2)reservoirs at 110℃and 20,000 mg/L salinity,with long-term stability over 60 days.The plugging rate of AR-Gel for fractured co re was 97%,with subsequent CO_(2)flooding re sulting in an enhanced oil recovery by 34.5%.ARGel can effectively control CO_(2)gas channeling and enhanced oil recovery.It offers a new material with high strength and temperature resistance,which is particularly beneficial in the CO_(2)flooding for the conformance control of oil field.展开更多
This study numerically examines the heat and mass transfer characteristics of two ternary nanofluids via converging and diverg-ing channels.Furthermore,the study aims to assess two ternary nanofluids combinations to d...This study numerically examines the heat and mass transfer characteristics of two ternary nanofluids via converging and diverg-ing channels.Furthermore,the study aims to assess two ternary nanofluids combinations to determine which configuration can provide better heat and mass transfer and lower entropy production,while ensuring cost efficiency.This work bridges the gap be-tween academic research and industrial feasibility by incorporating cost analysis,entropy generation,and thermal efficiency.To compare the velocity,temperature,and concentration profiles,we examine two ternary nanofluids,i.e.,TiO_(2)+SiO_(2)+Al_(2)O_(3)/H_(2)O and TiO_(2)+SiO_(2)+Cu/H_(2)O,while considering the shape of nanoparticles.The velocity slip and Soret/Dufour effects are taken into consideration.Furthermore,regression analysis for Nusselt and Sherwood numbers of the model is carried out.The Runge-Kutta fourth-order method with shooting technique is employed to acquire the numerical solution of the governed system of ordinary differential equations.The flow pattern attributes of ternary nanofluids are meticulously examined and simulated with the fluc-tuation of flow-dominating parameters.Additionally,the influence of these parameters is demonstrated in the flow,temperature,and concentration fields.For variation in Eckert and Dufour numbers,TiO_(2)+SiO_(2)+Al_(2)O_(3)/H_(2)O has a higher temperature than TiO_(2)+SiO_(2)+Cu/H_(2)O.The results obtained indicate that the ternary nanofluid TiO_(2)+SiO_(2)+Al_(2)O_(3)/H_(2)O has a higher heat transfer rate,lesser entropy generation,greater mass transfer rate,and lower cost than that of TiO_(2)+SiO_(2)+Cu/H_(2)O ternary nanofluid.展开更多
To accurately diagnosemisfire faults in automotive engines,we propose a Channel Attention Convolutional Model,specifically the Squeeze-and-Excitation Networks(SENET),for classifying engine vibration signals and precis...To accurately diagnosemisfire faults in automotive engines,we propose a Channel Attention Convolutional Model,specifically the Squeeze-and-Excitation Networks(SENET),for classifying engine vibration signals and precisely pinpointing misfire faults.In the experiment,we established a total of 11 distinct states,encompassing the engine’s normal state,single-cylinder misfire faults,and dual-cylinder misfire faults for different cylinders.Data collection was facilitated by a highly sensitive acceleration signal collector with a high sampling rate of 20,840Hz.The collected data were methodically divided into training and testing sets based on different experimental groups to ensure generalization and prevent overlap between the two sets.The results revealed that,with a vibration acceleration sequence of 1000 time steps(approximately 50 ms)as input,the SENET model achieved a misfire fault detection accuracy of 99.8%.For comparison,we also trained and tested several commonly used models,including Long Short-Term Memory(LSTM),Transformer,and Multi-Scale Residual Networks(MSRESNET),yielding accuracy rates of 84%,79%,and 95%,respectively.This underscores the superior accuracy of the SENET model in detecting engine misfire faults compared to other models.Furthermore,the F1 scores for each type of recognition in the SENET model surpassed 0.98,outperforming the baseline models.Our analysis indicated that the misclassified samples in the LSTM and Transformer models’predictions were primarily due to intra-class misidentifications between single-cylinder and dual-cylinder misfire scenarios.To delve deeper,we conducted a visual analysis of the features extracted by the LSTM and SENET models using T-distributed Stochastic Neighbor Embedding(T-SNE)technology.The findings revealed that,in the LSTMmodel,data points of the same type tended to cluster together with significant overlap.Conversely,in the SENET model,data points of various types were more widely and evenly dispersed,demonstrating its effectiveness in distinguishing between different fault types.展开更多
基金supported by the National Natural Science Foundation of China(Nos.61401030 and 61501093)
文摘We study the optimal precoding for a full-duplex (FD) system, where one FD multi-antenna base station (BS) respectively transmits to and receives from two half-duplex single-antenna mobile users (MUs) on the same time slot and frequency band. At the FD BS, the received signal from the desired MU is severely affected by the extremely strong self-interference (SI) from its transmit antennas to the receive antennas. In the presence of residual SI after imperfect SI cancellation, the downlink transmission rate maximization problem subject to a targeted uplink rate is formulated as a non-convex optimization problem to characterize the achievable rate region for the considered system. Considering the case in which the SI channel is strongly correlated, the above problem is transformed into a convex problem by exploiting the rank-one property of the SI channel, which can be solved efficiently. Finally, numerical results validate the effectiveness of the proposed scheme.
基金supported by National Natural Science Foundation of China (Nos.61172107,61172110)National High Technical Research and Development Program (863 Program) of China (No.2015AA016306)+1 种基金Major Projects in Liaoning Province Science and Technology Innovation (No.201302001)Fundamental Research Funds for the Central Universities of China (No.DUT13LAB06)
文摘The 3-D beamforming scheme has elite as evolving interest because of its efficiency to empower assorted techniques such as vertical and horizontal domains and emanation beamforming according to subscriber's provisions. Usually, 3-D beamforming communication is set up on FDD/TDD approach those effects on the performance of spectrum and energy efficiency. Co-frequency and CoTime Full Duplex(CCFD) is an effective solution to improve the spectrum and energy efficiency by transmitting and receiving simultaneously in frequency and time domain. While, CCFD communication often face the self-interference issue when communication occurs, simultaneously. Consequently, in this paper a self-interference elimination by physical feedback channel in CCFD for 3-D Beamforming communication scheme is proposed to improve the over-all system performance in terms of energy and spectrum efficiency. The simulation and analytical outcomes demonstrated that the proposed system is superior than the traditional one.
基金supported in part by the National Natural Science Foundation of China under Grant 62071094in part by the National Key Laboratory of Wireless Communications Foundation under Grant IFN202402in part by the Postdoctoral Fellowship Program(Grade C)of China Postdoctoral Science Foundation under Grant GZC20240217.
文摘To enable simultaneous transmit and receive(STAR)on the same frequency in a densely deployed space with multi-interference sources,this work proposes a digitally-assisted analog selfinterference cancellation method,which can acquire reference signals through flexible wired/wireless switching access.Based on this method,the Minimum Mean Square Error algorithm with known channel state information is derived in detail,determining the upper limit of the cancellation performance,and the Adaptive Dithered Linear Search algorithm for real-time engineering cancellation is given.The correctness of theoretical analysis is verified by the practical self-interference channel measured by a vector network analyzer.Furthermore,we have designed and implemented the corresponding multiinterference cancellation prototype with the digitallyassisted structure,capable of handling multiple interferences(up to three)and supporting a large receive bandwidth of 100 MHz as well as a wide frequency coverage from 30 MHz to 3000 MHz.Prototype test results demonstrate that in the presence of three interferences,when the single interference bandwidth is 0.2/2/20 MHz(corresponding to the receive bandwidth of 2/20/100 MHz),the cancellation performance can reach 46/32/22 dB or more.
基金supported by the Shan⁃dong Provincial Natural Science Foundation(No.ZR2022MF314).
文摘The adaptive filtering algorithm with a fixed projection order is unable to adjust its performance in response to changes in the external environment of airborne radars.To overcome this limitation,a new approach is introduced,which is the variable projection order Ekblom norm-promoted adaptive algorithm(VPO-EPAA).The method begins by examining the mean squared deviation(MSD)of the EPAA,deriving a formula for its MSD.Next,it compares the MSD of EPAA at two different projection orders and selects the one that minimizes the MSD as the parameter for the current iteration.Furthermore,the algorithm’s computational complexity is analyzed theoretically.Simulation results from system identification and self-interference cancellation show that the proposed algorithm performs exceptionally well in airborne radar signal self-interference cancellation,even under various noise intensities and types of interference.
基金supported by the National Natural Science Foundation of China,Nos.82172196(to KX),82372507(to KX)the Natural Science Foundation of Hunan Province,China,No.2023JJ40804(to QZ)the Key Laboratory of Emergency and Trauma(Hainan Medical University)of the Ministry of Education,China,No.KLET-202210(to QZ)。
文摘Ischemia–reperfusion injury is a common pathophysiological mechanism in retinal degeneration.PANoptosis is a newly defined integral form of regulated cell death that combines the key features of pyroptosis,apoptosis,and necroptosis.Oligomerization of mitochondrial voltage-dependent anion channel 1 is an important pathological event in regulating cell death in retinal ischemia–reperfusion injury.However,its role in PANoptosis remains largely unknown.In this study,we demonstrated that voltage-dependent anion channel 1 oligomerization-mediated mitochondrial dysfunction was associated with PANoptosis in retinal ischemia–reperfusion injury.Inhibition of voltage-dependent anion channel 1 oligomerization suppressed mitochondrial dysfunction and PANoptosis in retinal cells subjected to ischemia–reperfusion injury.Mechanistically,mitochondria-derived reactive oxygen species played a central role in the voltagedependent anion channel 1-mediated regulation of PANoptosis by promoting PANoptosome assembly.Moreover,inhibiting voltage-dependent anion channel 1 oligomerization protected against PANoptosis in the retinas of rats subjected to ischemia–reperfusion injury.Overall,our findings reveal the critical role of voltage-dependent anion channel 1 oligomerization in regulating PANoptosis in retinal ischemia–reperfusion injury,highlighting voltage-dependent anion channel 1 as a promising therapeutic target.
基金supported by ANID-FONDECYT 1200908(to JF),ANID-FONDECYT 1211082 and 1250856(to GEY)by the Millennium Nucleus for the Study of Pain NCN19_038(Mi Nu SPain)(to GEY)funded by the ANID scholarship 21201176。
文摘Numerous pathological states of the nervous system involve alterations in neuronal excitability and synaptic dysfunction,which depend on the function of ion channels.Due to their critical involvement in health and disease,the search for new compounds that modulate these proteins is still relevant.Traditional medicine has long been a rich source of neuroactive compounds.For example,the indigenous Mapuche people have used the leaves and bark of the Drimys winteri tree for centuries to treat various diseases.Consequently,several studies have investigated the biological effects of compounds in Drimys winteri,highlighting sesquiterpenes such asα-humulene,drimenin,polygodial,andα-,β-,γ-eudesmol.However,there is currently no literature review focusing on the ability of these sesquiterpenes to modulate ion channels.This review summarizes the current knowledge about neuroactive compounds found in Drimys winteri,with special emphasis on their direct actions on neuronal ion channels.Several Drimys winteri sesquiterpenes modulate a diverse array of neuronal ion channels,including transient receptor potential channels,gamma-aminobutyric acid A receptors,nicotinic acetylcholine receptors,and voltage-dependent Ca^(2+)and Na^(+)channels.Interestingly,the modulation of these molecular targets by Drimys winteri sesquiterpenes correlates with their therapeutic actions.The promiscuous pharmacological profile of Drimys winteri sesquiterpenes suggests they modulate multiple protein targets in vivo,making them potentially useful for treating complex,multifactorial diseases.Further studies at the molecular level may aid in developing multitargeted drugs with enhanced therapeutic effects.
基金supported by National Natural Science Foundation of China(NSFC)under grant U23A20310.
文摘With the growing advancement of wireless communication technologies,WiFi-based human sensing has gained increasing attention as a non-intrusive and device-free solution.Among the available signal types,Channel State Information(CSI)offers fine-grained temporal,frequency,and spatial insights into multipath propagation,making it a crucial data source for human-centric sensing.Recently,the integration of deep learning has significantly improved the robustness and automation of feature extraction from CSI in complex environments.This paper provides a comprehensive review of deep learning-enhanced human sensing based on CSI.We first outline mainstream CSI acquisition tools and their hardware specifications,then provide a detailed discussion of preprocessing methods such as denoising,time–frequency transformation,data segmentation,and augmentation.Subsequently,we categorize deep learning approaches according to sensing tasks—namely detection,localization,and recognition—and highlight representative models across application scenarios.Finally,we examine key challenges including domain generalization,multi-user interference,and limited data availability,and we propose future research directions involving lightweight model deployment,multimodal data fusion,and semantic-level sensing.
基金supported by the research grant from Huawei Technologies(Sweden)ABsupported by the U.K.Engineering and Physical Sciences Research Council(EPSRC)under Grant EP/P009549/1。
文摘The in-band full-duplex(IBFD)mechanism is of interest in beyond 5 G systems due to its potential to enhance spectral efficiency and reduce delay.To achieve the maximum gain of IBFD systems,the significant self-interference(SI)must be efficiently suppressed.The challenges of wideband selfinterference cancellation(SIC)lie in the radio frequency(RF)domain,where the performance will be limited by the hardware.This paper reviews current RF cancellation mechanisms and investigates an efficient mechanism for future wideband systems with minimum complexity.The working principle and implementation details of multi-tap cancellers are first introduced,then an optical domain-based RF canceller is reviewed,and a novel low-cost design is proposed.To minimize the cost and complexity of the canceller,the minimum required number of taps are analyzed.Simulation results show that with the commonly used 12-bits analog-to-digital converter(ADC)at the receiver,the novel optical domain-based canceller can enable efficient SIC in the 3 GPP LTE specifications compatible system within 400 MHz bandwidth.
基金supported by the National Natural Science Foundation of China under Grants 61372092"863" Program under Grants 2014AA01A701
文摘Full duplex radio increases the frequency efficiency but its performance is limited by the self-interference （SI）. We first analyze the multiple noises in the full duplex radio system and model such noises as an α - stable distribution. Then we formulate a novel non-Gaussian SI problem. Under the maximum correntropy criterion （MCC）, a robust digital non-linear self-interference cancellation algorithm is proposed for the SI channel estimation. A gradient descent based algorithm is derived to search the optimal solution. Simulation results show that the proposed algorithm can achieve a smaller estimation error and a higher pseudo signal to interference plus noise ratio （PSINR） than the well-known least mean square （LMS） algorithm and least square （LS） algorithm.
基金supported by the National Natural Science Foundations of China under Grant No.61501050 and No.61271177
文摘In MIMO full duplex system,power amplifier(PA) nonlinearity limits the self-interference(SI) cancellation seriously. Most existing methods need to model and estimate the PA nonlinearity in order to reconstruct the SI,however the estimation error caused by the mismatch between the estimated PA model and the actual PA property still impacts the cancellation ability,especially when the transmit power is high. In this paper we propose a polarization oblique projection based self-interference cancellation method which does not need to estimate the PA nonlinearity coefficients. It exploits the polarization state information of the signals which is immune to the PA nonlinearity,and establishes an oblique projection operator to cancel the SI. Numerical results and analysis demonstrate that it can cancel the nonlinear SI effectively. Moreover the signal to interfere plus noise ratio(SINR) and the achievable sum rate do not deteriorate when the transmit power is high. Further,the upper bound of the achievable sum rate can be more than twice that of the half duplex.
基金This work was supported by the National Nature Science Foundation of China(No.61971080,No.61471076)Chongqing Research Program of Basic Research and Frontier Exploration(No.cstc2018jcyjAX0432)the Key Project of Science and Technology Research of Chongqing Education Commission(No.KJZD-K201800603,No.KJZD-M201900602).
文摘We discuss the physical layer security scheme in the Full-Duplex(FD)MIMO point-to-point two-way communication system with residual self-interference,in which legitimate nodes send confidential information and null space Artificial Noise(AN)while receiving information.Because the Channel State Information(CSI)of the eavesdropper is unavailable,we optimize the covariance matrices of the information signal as well as the allocation of the antenna for transmitting and receiving to minimize the signal power consumption under the target rate constraint.As a result,the power of AN is maximized within the limit of total power,so the interception capability of the eavesdropper is suppressed as much as possible.Since self-interference cannot be completely eliminated,the optimization process of one legitimate node depends on the optimization result of the other.By substituting self-interference power in the secrecy rate formula with its average value,the joint optimization process at the two nodes is transformed into two separate and solvable optimization processes.Then,the Water-Filling Algorithm(WFA)and bisection algorithm are used to get the optimal covariance matrices of the signal.Furthermore,we derive the theoretical lower bound of ergodic achievable secrecy rate under rayleigh channels to evaluate the performance of the scheme.The simulation results show that the theoretical derivation is correct,and the actual achievable rate is very close to the target rate,which means that the approximation in the optimization is feasible.The results also show that secrecy transmission can be realized because a considerable secrecy rate can be achieved.
文摘Adaptive digital self-interference cancellation(ADSIC)is a significant method to suppress self-interference and improve the performance of the linear frequency modulated continuous wave(LFMCW)radar.Due to efficient implementation structure,the conventional method based on least mean square(LMS)is widely used,but its performance is not sufficient for LFMCW radar.To achieve a better self-interference cancellation(SIC)result and more optimal radar performance,we present an ADSIC method based on fractional order LMS(FOLMS),which utilizes the multi-path cancellation structure and adaptively updates the weight coefficients of the cancellation system.First,we derive the iterative expression of the weight coefficients by using the fractional order derivative and short-term memory principle.Then,to solve the problem that it is difficult to select the parameters of the proposed method due to the non-stationary characteristics of radar transmitted signals,we construct the performance evaluation model of LFMCW radar,and analyze the relationship between the mean square deviation and the parameters of FOLMS.Finally,the theoretical analysis and simulation results show that the proposed method has a better SIC performance than the conventional methods.
基金Supported by the Natural Science Foundation of Hubei Province(2019CFB593)the National Natural Science Foundation of China(61961016)+1 种基金Ph.D.Research Start-up Foundation of Hubei Minzu University(MY2018B08)Graduate Education Innovation Plan of Hubei Minzu University(DC2000000119)。
文摘This paper presents a design scheme of wire-line telephone system using self-interference(SI)cancellation technology in co-frequency co-time full-duplex(CCFD)system to realize absolute secure communication at the physical layer.This scheme can hide the target signal by skillfully releasing the high-power artificial noise to the whole link at the receiving node,and then make use of the receiver’s knowledge of the SI signal to achieve high dB SI cancellation with the help of analog domain SI cancellation technology in CCFD domain,so that the signal-to-noise ratio(SNR)received by the eavesdropper at any position of the link is far lower than that of the legitimate receiver,so as to realize the absolutely secure communication in the sense of Wyner principle.This paper not only puts forward the specific design scheme of absolutely secure communication telephone,but also analyzes the calculation of security capacity under different eavesdropping positions,different SI cancellation capability and different system parameters according to Shannon theory.
基金supported in part by the National Natural Science Foundation of China(No.61601027)
文摘In this paper,a general scheme in digital self-interference cancellation at baseband for zero-IF full-duplex transceivers is presented. We model the self-interference signals specifically with only the nonlinear distortion signals falling in receiving band considered. A joint estimation algorithm is proposed for compensating the time delay and frequency offset taking into account the IQ amplitude and phase imbalances from mixers. The memory effect and nonlinear distortion are adaptively estimated by the de-correlated normalized least mean square(DNLMS) algorithm. Numerical simulation results demonstrate that the proposed self-interference cancellation scheme can efficiently compensate the self-interference and outperform the existing traditional solutions.
基金supported in part by the National Key Research and Development Program of China under Grant No.2024YFE0200600the Zhejiang Provincial Natural Science Foundation of China under Grant No.LR23F010005the Huawei Cooperation Project under Grant No.TC20240829036。
文摘Along with the proliferating research interest in semantic communication(Sem Com),joint source channel coding(JSCC)has dominated the attention due to the widely assumed existence in efficiently delivering information semantics.Nevertheless,this paper challenges the conventional JSCC paradigm and advocates for adopting separate source channel coding(SSCC)to enjoy a more underlying degree of freedom for optimization.We demonstrate that SSCC,after leveraging the strengths of the Large Language Model(LLM)for source coding and Error Correction Code Transformer(ECCT)complemented for channel coding,offers superior performance over JSCC.Our proposed framework also effectively highlights the compatibility challenges between Sem Com approaches and digital communication systems,particularly concerning the resource costs associated with the transmission of high-precision floating point numbers.Through comprehensive evaluations,we establish that assisted by LLM-based compression and ECCT-enhanced error correction,SSCC remains a viable and effective solution for modern communication systems.In other words,separate source channel coding is still what we need.
基金supported by the National Natural Science Foundation of China,Nos.81901098(to TC),82201668(to HL)Fujian Provincial Health Technology Project,No.2021QNA072(to HL)。
文摘The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central nervous system, with sensory stimulation and excitation conduction functions. Astrocytes and microglia belong to the glial cell family, which is the main source of cytokines and represents the main defense system of the central nervous system. Nerve cells undergo neurotransmission or gliotransmission, which regulates neuronal activity via the ion channels, receptors, or transporters expressed on nerve cell membranes. Ion channels, composed of large transmembrane proteins, play crucial roles in maintaining nerve cell homeostasis. These channels are also important for control of the membrane potential and in the secretion of neurotransmitters. A variety of cellular functions and life activities, including functional regulation of the central nervous system, the generation and conduction of nerve excitation, the occurrence of receptor potential, heart pulsation, smooth muscle peristalsis, skeletal muscle contraction, and hormone secretion, are closely related to ion channels associated with passive transmembrane transport. Two types of ion channels in the central nervous system, potassium channels and calcium channels, are closely related to various neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. Accordingly, various drugs that can affect these ion channels have been explored deeply to provide new directions for the treatment of these neurological disorders. In this review, we focus on the functions of potassium and calcium ion channels in different nerve cells and their involvement in neurological disorders such as Parkinson's disease, Alzheimer's disease, depression, epilepsy, autism, and rare disorders. We also describe several clinical drugs that target potassium or calcium channels in nerve cells and could be used to treat these disorders. We concluded that there are few clinical drugs that can improve the pathology these diseases by acting on potassium or calcium ions. Although a few novel ion-channelspecific modulators have been discovered, meaningful therapies have largely not yet been realized. The lack of target-specific drugs, their requirement to cross the blood–brain barrier, and their exact underlying mechanisms all need further attention. This review aims to explain the urgent problems that need research progress and provide comprehensive information aiming to arouse the research community's interest in the development of ion channel-targeting drugs and the identification of new therapeutic targets for that can increase the cure rate of nervous system diseases and reduce the occurrence of adverse reactions in other systems.
基金project was supported by the Fund of State Key Laboratory of Deep Oil and Gas,China University of Petroleum(East China)(No.SKLDOG2024-ZYRC-06)Key Program of National Natural Science Foundation of China(52130401)+1 种基金National Natural Science Foundation of China(52104055,52374058)Shandong Provincial Natural Science Foundation,China(ZR2021ME171,ZR2024YQ043)。
文摘CO_(2)flooding enhanced oil recovery(CO_(2)-EOR)represents a significant technology in the low permeability reservoir.With the fractures and heterogeneity in low permeability reservoirs,CO_(2)-EOR is susceptible to pessimistic gas channeling.Consequently,there is a need to develop conformance control materials that can be used in CO_(2)-EOR.Herein,to address the challenges of low strength and poor stability of polymer gel in high temperature and low permeability reservoirs,a new organic/metal ion composite crosslinking polymer gel(AR-Gel)is reported,which is formed by low hydrolysis and medium to high molecular weight polymer(CX-305),organic crosslinking agent(phenolic resin),and aluminium citrate(AI(Ⅲ)).The crosslinking of AI(Ⅲ)with carboxyl group and organic/metal ion double crosslinking can construct a more complex and stable polymer gel structure on the basis of traditional chemical crosslinking,to cope with the harsh conditions such as high temperature.The structure-activity relationship of AR-Gel was revealed by rheology behavior and micro-morphology.The applicability of AR-Gel in reservoir was investigated,as was its strength and stability in supercritical CO_(2).The anti-gas channeling and enhanced oil recovery of AR-Gel were investigated using low permeability fractured cores,and the field process parameters were provided.The gel can be used to meet supercritical CO_(2)reservoirs at 110℃and 20,000 mg/L salinity,with long-term stability over 60 days.The plugging rate of AR-Gel for fractured co re was 97%,with subsequent CO_(2)flooding re sulting in an enhanced oil recovery by 34.5%.ARGel can effectively control CO_(2)gas channeling and enhanced oil recovery.It offers a new material with high strength and temperature resistance,which is particularly beneficial in the CO_(2)flooding for the conformance control of oil field.
基金supported by DST-FIST(Government of India)(Grant No.SR/FIST/MS-1/2017/13)and Seed Money Project(Grant No.DoRDC/733).
文摘This study numerically examines the heat and mass transfer characteristics of two ternary nanofluids via converging and diverg-ing channels.Furthermore,the study aims to assess two ternary nanofluids combinations to determine which configuration can provide better heat and mass transfer and lower entropy production,while ensuring cost efficiency.This work bridges the gap be-tween academic research and industrial feasibility by incorporating cost analysis,entropy generation,and thermal efficiency.To compare the velocity,temperature,and concentration profiles,we examine two ternary nanofluids,i.e.,TiO_(2)+SiO_(2)+Al_(2)O_(3)/H_(2)O and TiO_(2)+SiO_(2)+Cu/H_(2)O,while considering the shape of nanoparticles.The velocity slip and Soret/Dufour effects are taken into consideration.Furthermore,regression analysis for Nusselt and Sherwood numbers of the model is carried out.The Runge-Kutta fourth-order method with shooting technique is employed to acquire the numerical solution of the governed system of ordinary differential equations.The flow pattern attributes of ternary nanofluids are meticulously examined and simulated with the fluc-tuation of flow-dominating parameters.Additionally,the influence of these parameters is demonstrated in the flow,temperature,and concentration fields.For variation in Eckert and Dufour numbers,TiO_(2)+SiO_(2)+Al_(2)O_(3)/H_(2)O has a higher temperature than TiO_(2)+SiO_(2)+Cu/H_(2)O.The results obtained indicate that the ternary nanofluid TiO_(2)+SiO_(2)+Al_(2)O_(3)/H_(2)O has a higher heat transfer rate,lesser entropy generation,greater mass transfer rate,and lower cost than that of TiO_(2)+SiO_(2)+Cu/H_(2)O ternary nanofluid.
基金Yongxian Huang supported by Projects of Guangzhou Science and Technology Plan(2023A04J0409)。
文摘To accurately diagnosemisfire faults in automotive engines,we propose a Channel Attention Convolutional Model,specifically the Squeeze-and-Excitation Networks(SENET),for classifying engine vibration signals and precisely pinpointing misfire faults.In the experiment,we established a total of 11 distinct states,encompassing the engine’s normal state,single-cylinder misfire faults,and dual-cylinder misfire faults for different cylinders.Data collection was facilitated by a highly sensitive acceleration signal collector with a high sampling rate of 20,840Hz.The collected data were methodically divided into training and testing sets based on different experimental groups to ensure generalization and prevent overlap between the two sets.The results revealed that,with a vibration acceleration sequence of 1000 time steps(approximately 50 ms)as input,the SENET model achieved a misfire fault detection accuracy of 99.8%.For comparison,we also trained and tested several commonly used models,including Long Short-Term Memory(LSTM),Transformer,and Multi-Scale Residual Networks(MSRESNET),yielding accuracy rates of 84%,79%,and 95%,respectively.This underscores the superior accuracy of the SENET model in detecting engine misfire faults compared to other models.Furthermore,the F1 scores for each type of recognition in the SENET model surpassed 0.98,outperforming the baseline models.Our analysis indicated that the misclassified samples in the LSTM and Transformer models’predictions were primarily due to intra-class misidentifications between single-cylinder and dual-cylinder misfire scenarios.To delve deeper,we conducted a visual analysis of the features extracted by the LSTM and SENET models using T-distributed Stochastic Neighbor Embedding(T-SNE)technology.The findings revealed that,in the LSTMmodel,data points of the same type tended to cluster together with significant overlap.Conversely,in the SENET model,data points of various types were more widely and evenly dispersed,demonstrating its effectiveness in distinguishing between different fault types.
