Objective This study examines the sequential mediating roles of body pain and self-reported health in the association between sleep duration and self-reported life satisfaction among elderly Chinese adults.Methods Dat...Objective This study examines the sequential mediating roles of body pain and self-reported health in the association between sleep duration and self-reported life satisfaction among elderly Chinese adults.Methods Data from the fifth wave of the China Health and Retirement Longitudinal Survey(CHARLS)were used to analyse the relationships between sleep duration and body pain,self-reported health,and life satisfaction through logistic regression and Restricted Cubic Spline(RCS)analyses.The sequential mediation effects of body pain and self-reported health status were examined via chain mediation analysis.Results Logistic regression analysis showed that sleeping fewer than 6 hours or 6-7 hours was linked to higher risks of body pain,poor health,and dissatisfaction with life compared to sleeping 7-8 hours(all P<0.05).Additionally,those sleeping more than 9 hours also had increased risks of poor health and dissatisfaction with life compared to those sleeping 7-8 hours(all P<0.05).Chain mediation analysis showed that body pain and self-reported health status sequentially mediated 46.15%of the association between sleep duration and life satisfaction.Conclusion Body pain and self-reported health may shape the relationship between sleep duration and life satisfaction in elderly Chinese adults.展开更多
Objectives: We measured health inequalities among employed Luxembourg residents over time and the socio-economic and work-related determinants. Design and Setting: Longitudinal data were obtained from the Socio-econom...Objectives: We measured health inequalities among employed Luxembourg residents over time and the socio-economic and work-related determinants. Design and Setting: Longitudinal data were obtained from the Socio-economic Liewen zu Lëtzebuerg/European Union Survey on Income and Living Conditions, which has been conducted each year since 2003 in Luxembourg. Participants: Participants comprised 727 Luxembourg residents (58% men), aged between 21 and 55 years in 2003, who were employed between 2003 and 2012. Primary and Secondary Outcomes Measured: The variable of interest was self-reported health. We used transition indicators on work-related factors to consider changes that individuals may have experienced in their job over this period. Results: People who moved from a part-time to a full-time contract (odds ratio (OR): 5.52, confidence interval (CI): 1.55 - 19.73), and those who moved from the 3rd or 4th quartile of earnings to the 1st or 2nd quartile (OR: 2.48, CI: 1.02 - 6.05) between 2003 and 2012, had a higher risk of being in poor health in 2012. The risk of deterioration in self-reported health in 2012 among people who were healthy in 2003 was associated with the type of contract, economic activity, and occupation. Conclusion: Health inequalities occur among employed people in Luxembourg. Their importance varies according to work-related characteristics and economic activity. Our findings showed that declined health status was associated with contract type, profession, and economic activity. This suggests that measures should be taken to maintain good health for people working in these specific occupations or economic sectors (e.g. preventive action, reduction of risk exposure, change of occupation in the same company, and so on).展开更多
There has been lack of studies that examine the relationship between self-rated health(SRH)and alcohol consumption,particularly in middle-aged and older adult populations.This study aims to investigate association of ...There has been lack of studies that examine the relationship between self-rated health(SRH)and alcohol consumption,particularly in middle-aged and older adult populations.This study aims to investigate association of SRH status with alcohol consumption in middle-aged and older adult populations.The study is a cross-sec-tional study design that was based on the China Health and Retired Longitudinal study(CHARLS)and the Canadian Alcohol and Drug Monitoring Survey(CAD-UMS)and the Canadian Alcohol,Tobacco and Drug Survey(CTADS).Measure of health is SRH status and self-reported alcohol use.Multinomial logistic regres-sion was performed to model the data and the odds ratio of self-reported excel-lent,very good,good and fair(versus poor)for current and former drinkers versus nondrinkers and current drinkers versus former drinkers was estimated in models after adjusting for covariates.This study found that in both Chinese and Canadian adult populations,current drinkers reported better health status than former drink-ers;lifetime nondrinkers reported better health status than former drinkers.Current drinkers reported better health status than nondrinkers.Canadian moderate drinkers(1.3-44 g per day)tended to report better health compared with occasional drinkers and Chinese heavy drinkers(45+grams per day)reported better health status com-pared with occasional drinkers in both populations.This study found current drink-ers tended to have better health status than former drinker and lifetime nondrinkers in adult populations.Nondrinkers tended to report better health status than former drinkers.Low and medium drinkers reported better health status.展开更多
AIM:To determine the prevalence and associations of non-retinopathy ocular conditions among older Australian adults with diabetes.METHODS:Multistage random-cluster sampling was used to select 3098 non-indigenous Austr...AIM:To determine the prevalence and associations of non-retinopathy ocular conditions among older Australian adults with diabetes.METHODS:Multistage random-cluster sampling was used to select 3098 non-indigenous Australians aged 50 y or older(46.4%male)and 1738 indigenous Australians aged 40 y or older(41.1%male)from all levels of geographic remoteness in Australia.Participants underwent a standardised questionnaire to ascertain diabetes history,and a clinical examination to identify eye disease.We determined the prevalence of uncorrected refractive error,visually significant cataract,cataract surgery,age-related macular degeneration,glaucoma,ocular hypertension,retinal vein occlusion and epiretinal membrane among those with and without self-reported diabetes.RESULTS:Participants with self-reported diabetes had a higher prevalence of cataract surgery than those without diabetes(28.8%vs 16.9%,OR 1.78,95%CI:1.35-2.34 among non-indigenous Australians,and 11.3%vs 5.2%,OR 1.62,95%CI:1.22-2.14 among indigenous Australians).Diabetic retinopathy(DR)increased the odds of cataract surgery among self-reported diabetic indigenous and nonindigenous Australians(OR 1.89,P=0.004 and OR 2.33,P<0.001 respectively).Having diabetes for≥20 y and having vision-threatening DR increased the odds of cataract surgery among indigenous Australians with diabetes(OR 3.73,P=0.001 and 7.58,P<0.001,respectively).CONCLUSION:Most non-retinopathy ocular conditions are not associated with self-reported diabetes.However,to account for Australia’s worsening diabetes epidemic,interventions to reduce the impact of diabetes-related blindness should include increased cataract surgery services.展开更多
This study was aimed to evaluate the agreement between the self-reported sodium intake level and 24-h urine sodium excretion level in Chinese. The 24-h urine collection was conducted among 2112 adults aged 18-69 years...This study was aimed to evaluate the agreement between the self-reported sodium intake level and 24-h urine sodium excretion level in Chinese. The 24-h urine collection was conducted among 2112 adults aged 18-69 years randomly selected in Shandong Province, China. The subjects were asked whether their sodium intake was low, moderate, or high. The weighted kappa statistics was calculated to assess the agreement between 24-h urine sodium excretion level and self-reported sodium intake level. One third of the subjects reported low sodium intake level. About 70% of the subjects had mean 24-h sodium excretion 〉9 g/d, but reported low or moderate sodium intake.展开更多
Psychological stress and illness among hospital residences have been subject to increasing scientific scrutiny;however very few studies have been published to describe the extent of health status and psychological str...Psychological stress and illness among hospital residences have been subject to increasing scientific scrutiny;however very few studies have been published to describe the extent of health status and psychological stresses in residents in different specialties especially in our country that our study was mainly focused on this subject. Methods: The study subjects were medical residents in public hospitals covering 14 different specialties in Tehran in 2007. A self-administered questionnaire elicited information related to socio-demographic profile, specialty, duty hours, sleep quality, physical activity level, number of night shifts per month, mood changes, sense of depression after night shifts, fatigue, use of antidepressant and tranquilizer, and their opinion regarding their health status on a 4-point Likert scale. Results: 66.7% of participants were male with the mean age of 32.9 ± 4.2 years. 62.1% of the residents felt mood changes after nightly shifts that could adversely affect their daily living, quality of work, and social relationships. The overall prevalence of the use of antidepressant drugs was 20.0% which was significantly higher in women than men. Also, 24.4% of them reported consumption of sedative and hypnotic drugs. 15.6% reported complete healthy status while 9.4% reported partial illness. Complete healthy status was more reported among the residents of anesthesiology and pediatrics while illness was more reported by residents in pathology field. Residents’ satisfaction with their status was positively correlated with the year of residency and marriage, while dissatisfaction was more reported in divorced ones as well as in those with higher number of nightly shifts. Conclusion: Notable number of hospital residents in Iran experience significant stressors and emotional and mental health problems. Among all studies factors type of specialty, year of residency, female gender, number of nightly shifts, and single marital status were more important than other factors.展开更多
Analysis Method of ^(131)I Activity in Carbon Cartridge and Internal Dose Assessment for Nuclear Medicine Workers.Shuo Wang1,Fei Tuo1,Jian-feng Zhang1,Xiao-liang Li1,Bao-lu Yang1,Qiang Zhou1,Ze-shu Li1,Shu-ying Kong1,...Analysis Method of ^(131)I Activity in Carbon Cartridge and Internal Dose Assessment for Nuclear Medicine Workers.Shuo Wang1,Fei Tuo1,Jian-feng Zhang1,Xiao-liang Li1,Bao-lu Yang1,Qiang Zhou1,Ze-shu Li1,Shu-ying Kong1,and Wei-hao Qin1(1.National Institute for Radiological Protection,Chinese Center for Disease Control and Prevention,Beijing,100088,China.)展开更多
This study links social capital with people’s health and well-being using data from the seventh wave of the World Value Survey,logistic regression,and path analysis.The study’s findings show that happiness and life ...This study links social capital with people’s health and well-being using data from the seventh wave of the World Value Survey,logistic regression,and path analysis.The study’s findings show that happiness and life satisfaction are two different measures of the same construct,or well-being.The determinants of each are also characterised differently:while life satisfaction is more of a stable and relative measure and is more strongly influenced by civic cooperation,social participation,and educational attainment,happiness is more of an unstable measure and is more strongly influenced by community belonging,trust and confidence aggregates,including employment and location of residence of an individual.Moreover,freedom of choice,financial satisfaction or social comparison,and state of health were the most important factors influencing happiness and life satisfaction.The findings also show that self-reported health(SRH)has a greater impact on happiness than a measure of life satisfaction.Path analysis shows out of the three other components of social capital—community belonging,civic engagement,and social participation—trust and confidence aggregates are the ones that have the biggest impact on increased social capital.For both well-being measures,SRH mediated the relationship.The life satisfaction measure had a higher level of mediation of SRH than happiness,but social capital had a smaller direct impact on life satisfaction than on happiness.SRH was found to be partially mediating this relationship for both happiness and life satisfaction measures,which means that people with higher social capital reported feeling better off.展开更多
Healthy behavior has long been linked to mental health outcomes.However,the role of artificial intelligence(AI)literacy in shaping healthy behaviors and its potential impact on mental health remains underexplored.This...Healthy behavior has long been linked to mental health outcomes.However,the role of artificial intelligence(AI)literacy in shaping healthy behaviors and its potential impact on mental health remains underexplored.This paper presents a scoping review offering a novel perspective on the intersection of healthy behaviors,mental health,and AI literacy.By examining how individuals’understanding of AI influences their choices regarding nutrition and their susceptibility to mental health issues,the current study explores emerging trends in health behavior decision-making.This emphasizes the need for integrating AI literacy into mental health and health behaviors education,as well as the development of AI-driven tools to support healthier behavior choices.It highlights that individuals with low AI literacy may misinterpret or overly depend on AI guidance,resulting in maladaptive health choices,while those with high AI literacy may be more likely to engage reflectively and sustain positive behaviors.The paper outlines the importance of inclusive education,user-centered design,and community-based support systems to enhance AI literacy for digitally marginalized groups.AI literacy may be positioned as a key determinant of health equity,better allowing for interdisciplinary strategies that empower individuals to make informed,autonomous decisions that promote both physical and mental health.展开更多
Objective:To systematically sort out the application forms and effects of digital health intervention technologies in oral health management,and provide references for the digital development of stomatology.Methods:By...Objective:To systematically sort out the application forms and effects of digital health intervention technologies in oral health management,and provide references for the digital development of stomatology.Methods:By reviewing relevant domestic and foreign studies and clinical practices,this paper summarizes and analyzes the main application forms of digital health interventions,including digital health education,intelligent detection equipment,telemedicine platforms,oral health big data platforms,and school-hospital collaborative screening robots.Results:Studies have shown that digital health interventions can effectively improve the public’s oral health knowledge level,optimize personal health behaviors,enhance clinical diagnosis efficiency,reduce overall medical costs,and promote the innovation and upgrading of oral health management models.Conclusion:Digital health intervention represents an inevitable trend in the future development of stomatology.In the future,it is still necessary to improve data security and privacy protection,technology adaptability and popularity,as well as relevant policies and norms,to give full play to its potential value.展开更多
Concerned that fewer than 20%of adolescents meet the World Health Organization(WHO)’s physical activity(PA)guidelines of engaging in≥60 min each day of the week of moderate-to-vigorous PA(MVPA),classifying them as i...Concerned that fewer than 20%of adolescents meet the World Health Organization(WHO)’s physical activity(PA)guidelines of engaging in≥60 min each day of the week of moderate-to-vigorous PA(MVPA),classifying them as insufficiently active,1 Araujo et al.2 sought to identify the global prevalence of adolescents reporting less frequent MVPA(≥60 min per day of MVPA≥1 days per week)and identify differences in this prevalence by age,gender.展开更多
Academic journals,consulting firms,and mainstream media have often published“predictions”about the future develop-ment of medical and health care.These publications often emphasize the potential of cutting-edge scie...Academic journals,consulting firms,and mainstream media have often published“predictions”about the future develop-ment of medical and health care.These publications often emphasize the potential of cutting-edge scientific or technical breakthroughs.Health Care Science looks at the problem from another perspective.We focus on how these changes enter the health system,how they operate in the real world,and how they reshape the organization and governance of medical services.At the beginning of 2026,we envision the following three major shifts that will reshape healthcare.展开更多
Large-scale proteomics studies can refine our understanding of health and disease and enable precision medicine.Here,we provide a detailed atlas of 2,920 plasma proteins linking to diseases(406 prevalent and 660 incid...Large-scale proteomics studies can refine our understanding of health and disease and enable precision medicine.Here,we provide a detailed atlas of 2,920 plasma proteins linking to diseases(406 prevalent and 660 incident)and 986 health-related traits in 53,026 individuals(median follow-up:14.8 years)from the UK Biobank,representing the most comprehensive proteome profiles to date.This atlas revealed 168,100 protein-disease associations and 554,488 protein-trait associations.展开更多
Recently,inflammatory cytokine profiles have been linked to suicide risk in adolescents with non-suicidal self-injury,highlighting a promising biological dimension of suicide risk assessment.Clinical translation of th...Recently,inflammatory cytokine profiles have been linked to suicide risk in adolescents with non-suicidal self-injury,highlighting a promising biological dimension of suicide risk assessment.Clinical translation of the cytokine profiles into practice will require frontline engagement of the workforce.Mental health nurses are frequently the most accessible professionals in schools,communities,and low-resource settings and are prime candidates to bridge this gap.By integrating psychosocial evaluation with emerging biomarker data,they can deliver systematic risk assessment,continuous monitoring,and timely intervention.This role would not replace psychiatric expertise;it would extend the reach of psychiatric services,embedding suicide prevention across the continuum of care.For health systems,nurse-led integration may enhance capacity,equity,and resilience in responding to adolescent suicide risk.This editorial demonstrates that empowering nurses to operationalize biomarker-informed strategies is needed for advancing effective and sustainable suicide prevention in this vulnerable population.展开更多
The accelerating pace of population aging,the rising burden of chronic and non-communicable diseases,the increasing frequency of public health emergencies,and the growing imbalance and structural shortage of global he...The accelerating pace of population aging,the rising burden of chronic and non-communicable diseases,the increasing frequency of public health emergencies,and the growing imbalance and structural shortage of global healthcare resources are intensifying challenges.In the field of nursing,in particular,the latest State of the World’s Nursing Report[1]highlights that,although the current global number of nurses is approximately 29.8 million.展开更多
Objective:To systematically review the effects of administering metformin and glutathione alone and in coformulation with other compounds on the fertility and reproductive health of diabetic male rodents.Methods:The g...Objective:To systematically review the effects of administering metformin and glutathione alone and in coformulation with other compounds on the fertility and reproductive health of diabetic male rodents.Methods:The guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA)were followed to conduct this systematic review.Studies published until August 2024 in PubMed,Web of Science,and Scopus databases were searched,identified,screened,and selected for a detailed review.The keywords included metformin,diabetes,reproduction,glutathione,and rodent models.Results:A total of 166 studies were identified,of which 11 met the inclusion criteria and were included in the qualitative synthesis.One additional study was identified through snowballing and citation tracking,bringing the total to 12 studies.The findings indicate that metformin and glutathione,administered alone or in combination with other compounds,improved sperm count,motility,and morphology;restored reproductive hormone levels;reduced oxidative stress markers;and improved testicular histopathology in diabetic male rodents.Conclusions:Coformulation of metformin and glutathione with other compounds was found to be more effective in improving fertility and reproductive parameters in diabetic male rodents compared to mono-administration.However,further studies on the coformulation of metformin and glutathione are needed to confirm their efficacy and elucidate the underlying mechanisms.Study registration:The study protocol was registered in the International Prospective Register of Systematic Reviews(PROSPERO)with registration number CRD42024561820.展开更多
Background:Mental health concerns among doctoral students have become increasingly prominent,with consistently low levels of well-being making this issue a critical focus in higher education research.This study aims t...Background:Mental health concerns among doctoral students have become increasingly prominent,with consistently low levels of well-being making this issue a critical focus in higher education research.This study aims to synthesize existing evidence on the mental health and well-being of doctoral students and to identify key factors and intervention strategies reported in the literature.Methods:A systematic review was conducted to examine the determinants and interventions related to doctoral students’mental health and well-being.Relevant studies were comprehensively searched in Web of Science,PubMed,Scopus,and EBSCO,with the final search conducted on September 19,2025.Records were screened according to predefined criteria:empirical studies on doctoral students’mental health or well-being published in English were included,while non-empirical,non-English,and non-doctoral-student-focused studies were excluded.A total of 56 studies were included after rigorous screening.Results:Doctoral students’mental health and well-being are shaped by multiple interacting factors across individual,academic,interpersonal,organizational,and environmental levels.Moreover,variations in gender,identity,discipline,study stage,and institutional context may further exacerbate or mitigate psychological distress.Existing intervention studies primarily focus on three approaches:psychologically oriented training,practice-based behavioral and learning programs,and relationship-or support network-based initiatives.Conclusion:This review offers integrated evidence on doctoral students’mental health and well-being and highlights the need for universities to assume greater responsibility in developing systematic and responsive support mechanisms.Current research remains limited by insufficient cross-cultural comparison,a lack of intersectional perspectives,and a scarcity of large-scale,long-term evaluations of intervention effectiveness.Future studies should give greater attention to institutional contexts and vulnerable groups while expanding the scope and rigor of intervention research.展开更多
Objective:We assessed the risk for physical inactivity due to inadequate health literacy using multivariable analysis in a large middleaged population.Methods:This cross-sectional mail survey using a self-administered...Objective:We assessed the risk for physical inactivity due to inadequate health literacy using multivariable analysis in a large middleaged population.Methods:This cross-sectional mail survey using a self-administered questionnaire was conducted in 2020 and included 33,902 community residents aged 40-64 years from 5 cities in Osaka Prefecture,Japan.Of these,12,446(36.7%)agreed to participate in the survey.After exclusion of those with regular visits to medical institutions and those with missing data,the analysis included 3742 participants.Health literacy was measured by the communicative and critical health literacy(CCHL)scale,and participants were classified into 3 groups(low,medium,and high health literacy groups)by the tertiles of the CCHL scale score.Physical inactivity was defined as not completing at least 150 min of moderate-intensity physical activity throughout the week.Results:After adjustment for age,gender,education level,occupation,economic status,living alone,and stages of health behavior change,the multivariable-adjusted odds ratios(ORs)for physical inactivity were 1.36(95% confidence interval[CI]:1.16-1.59,P<0.001)in the medium health literacy group and 1.70(95%CI:1.36-2.11,P<0.001)in the low health literacy group compared with the high health literacy group.Conclusions:This large-scale study provides compelling evidence that those with inadequate health literacy are at higher risk for physical inactivity among middle-aged adults.展开更多
Overweight and obesity are significant public health concerns worldwide due to their association with many chronic health conditions.This has resulted in the development of various interventions focused on weight loss...Overweight and obesity are significant public health concerns worldwide due to their association with many chronic health conditions.This has resulted in the development of various interventions focused on weight loss to reduce the associated health burden.Physical activity is an important lifestyle behavior associated with enhanced health.Evidence supports that many of the benefits of physical activity are realized independent of initial weight status or whether weight loss is achieved,with some benefits additive to what is achieved with weight loss alone.These benefits include enhanced cardiometabolic,brain,cognitive and psychological health,and others.Moreover,in adults with overweight or obesity,physical activity has independent effects on cardiorespiratory fitness,muscular strength,physical function,and mobility.There are also benefits to body composition,with physical activity improving the quality of key tissues,such as skeletal muscle,which may not occur with diet-induced weight loss.Therefore,physical activity is an important public health target for adults with overweight or obesity to provide a wide range of health benefits that extend beyond those of weight loss alone.However,physical activity recommendations and programming efforts should consider the unique characteristics of adults with overweight or obesity to be most effective,and should support a focus on mobility,physical function,and other health outcomes.展开更多
Over the past decade,neonicotinoid insecticides have become the fastest-growing and most widely used class of pesticides.Initially,these compounds were considered ideal replacements for more hazardous chemicals such a...Over the past decade,neonicotinoid insecticides have become the fastest-growing and most widely used class of pesticides.Initially,these compounds were considered ideal replacements for more hazardous chemicals such as carbamates and organophosphates,due to their presumed limited impact on the environment and human health.However,neonicotinoids have since been detected in soils,surface waters,groundwater,food,and various human biological samples.Moreover,they have been shown to negatively affect aquatic organisms,including aquatic insects,crustaceans,mollusks,fish,algae/macrophytes,and amphibians.Epidemiological studies and human biomonitoring research have revealed both acute and chronic health effects,ranging from respiratory,cardiovascular,and neurological symptoms to congenital abnormalities.This review examines the effects of neonicotinoids,their ecological consequences,and the potential risks associated with human exposure.展开更多
基金supported by This work was supported by the Ministry of Science and Technology of the People’s Republic of China(STI2030-Major Projects2021ZD0201900)。
文摘Objective This study examines the sequential mediating roles of body pain and self-reported health in the association between sleep duration and self-reported life satisfaction among elderly Chinese adults.Methods Data from the fifth wave of the China Health and Retirement Longitudinal Survey(CHARLS)were used to analyse the relationships between sleep duration and body pain,self-reported health,and life satisfaction through logistic regression and Restricted Cubic Spline(RCS)analyses.The sequential mediation effects of body pain and self-reported health status were examined via chain mediation analysis.Results Logistic regression analysis showed that sleeping fewer than 6 hours or 6-7 hours was linked to higher risks of body pain,poor health,and dissatisfaction with life compared to sleeping 7-8 hours(all P<0.05).Additionally,those sleeping more than 9 hours also had increased risks of poor health and dissatisfaction with life compared to those sleeping 7-8 hours(all P<0.05).Chain mediation analysis showed that body pain and self-reported health status sequentially mediated 46.15%of the association between sleep duration and life satisfaction.Conclusion Body pain and self-reported health may shape the relationship between sleep duration and life satisfaction in elderly Chinese adults.
文摘Objectives: We measured health inequalities among employed Luxembourg residents over time and the socio-economic and work-related determinants. Design and Setting: Longitudinal data were obtained from the Socio-economic Liewen zu Lëtzebuerg/European Union Survey on Income and Living Conditions, which has been conducted each year since 2003 in Luxembourg. Participants: Participants comprised 727 Luxembourg residents (58% men), aged between 21 and 55 years in 2003, who were employed between 2003 and 2012. Primary and Secondary Outcomes Measured: The variable of interest was self-reported health. We used transition indicators on work-related factors to consider changes that individuals may have experienced in their job over this period. Results: People who moved from a part-time to a full-time contract (odds ratio (OR): 5.52, confidence interval (CI): 1.55 - 19.73), and those who moved from the 3rd or 4th quartile of earnings to the 1st or 2nd quartile (OR: 2.48, CI: 1.02 - 6.05) between 2003 and 2012, had a higher risk of being in poor health in 2012. The risk of deterioration in self-reported health in 2012 among people who were healthy in 2003 was associated with the type of contract, economic activity, and occupation. Conclusion: Health inequalities occur among employed people in Luxembourg. Their importance varies according to work-related characteristics and economic activity. Our findings showed that declined health status was associated with contract type, profession, and economic activity. This suggests that measures should be taken to maintain good health for people working in these specific occupations or economic sectors (e.g. preventive action, reduction of risk exposure, change of occupation in the same company, and so on).
文摘There has been lack of studies that examine the relationship between self-rated health(SRH)and alcohol consumption,particularly in middle-aged and older adult populations.This study aims to investigate association of SRH status with alcohol consumption in middle-aged and older adult populations.The study is a cross-sec-tional study design that was based on the China Health and Retired Longitudinal study(CHARLS)and the Canadian Alcohol and Drug Monitoring Survey(CAD-UMS)and the Canadian Alcohol,Tobacco and Drug Survey(CTADS).Measure of health is SRH status and self-reported alcohol use.Multinomial logistic regres-sion was performed to model the data and the odds ratio of self-reported excel-lent,very good,good and fair(versus poor)for current and former drinkers versus nondrinkers and current drinkers versus former drinkers was estimated in models after adjusting for covariates.This study found that in both Chinese and Canadian adult populations,current drinkers reported better health status than former drink-ers;lifetime nondrinkers reported better health status than former drinkers.Current drinkers reported better health status than nondrinkers.Canadian moderate drinkers(1.3-44 g per day)tended to report better health compared with occasional drinkers and Chinese heavy drinkers(45+grams per day)reported better health status com-pared with occasional drinkers in both populations.This study found current drink-ers tended to have better health status than former drinker and lifetime nondrinkers in adult populations.Nondrinkers tended to report better health status than former drinkers.Low and medium drinkers reported better health status.
基金Supported by Department of Health of the Australian Government,Novartis Australia and the Peggy and Leslie Cranbourne FoundationThe Principal Investigator,Dr Mohamed Dirani,is supported by an NHMRC Career Development Fellowship(No.1090466)supported by an Australian Postgraduate Award scholarship。
文摘AIM:To determine the prevalence and associations of non-retinopathy ocular conditions among older Australian adults with diabetes.METHODS:Multistage random-cluster sampling was used to select 3098 non-indigenous Australians aged 50 y or older(46.4%male)and 1738 indigenous Australians aged 40 y or older(41.1%male)from all levels of geographic remoteness in Australia.Participants underwent a standardised questionnaire to ascertain diabetes history,and a clinical examination to identify eye disease.We determined the prevalence of uncorrected refractive error,visually significant cataract,cataract surgery,age-related macular degeneration,glaucoma,ocular hypertension,retinal vein occlusion and epiretinal membrane among those with and without self-reported diabetes.RESULTS:Participants with self-reported diabetes had a higher prevalence of cataract surgery than those without diabetes(28.8%vs 16.9%,OR 1.78,95%CI:1.35-2.34 among non-indigenous Australians,and 11.3%vs 5.2%,OR 1.62,95%CI:1.22-2.14 among indigenous Australians).Diabetic retinopathy(DR)increased the odds of cataract surgery among self-reported diabetic indigenous and nonindigenous Australians(OR 1.89,P=0.004 and OR 2.33,P<0.001 respectively).Having diabetes for≥20 y and having vision-threatening DR increased the odds of cataract surgery among indigenous Australians with diabetes(OR 3.73,P=0.001 and 7.58,P<0.001,respectively).CONCLUSION:Most non-retinopathy ocular conditions are not associated with self-reported diabetes.However,to account for Australia’s worsening diabetes epidemic,interventions to reduce the impact of diabetes-related blindness should include increased cataract surgery services.
基金supported by funds from the Chinese Center for Disease Control and Prevention(China CDC)the National Center for Chronic and Non-communicable Disease Control and Prevention,China CDCthe Technical Development Plan in Shandong(implemented by Shandong CDC,Grant number:2012GSF11828)
文摘This study was aimed to evaluate the agreement between the self-reported sodium intake level and 24-h urine sodium excretion level in Chinese. The 24-h urine collection was conducted among 2112 adults aged 18-69 years randomly selected in Shandong Province, China. The subjects were asked whether their sodium intake was low, moderate, or high. The weighted kappa statistics was calculated to assess the agreement between 24-h urine sodium excretion level and self-reported sodium intake level. One third of the subjects reported low sodium intake level. About 70% of the subjects had mean 24-h sodium excretion 〉9 g/d, but reported low or moderate sodium intake.
文摘Psychological stress and illness among hospital residences have been subject to increasing scientific scrutiny;however very few studies have been published to describe the extent of health status and psychological stresses in residents in different specialties especially in our country that our study was mainly focused on this subject. Methods: The study subjects were medical residents in public hospitals covering 14 different specialties in Tehran in 2007. A self-administered questionnaire elicited information related to socio-demographic profile, specialty, duty hours, sleep quality, physical activity level, number of night shifts per month, mood changes, sense of depression after night shifts, fatigue, use of antidepressant and tranquilizer, and their opinion regarding their health status on a 4-point Likert scale. Results: 66.7% of participants were male with the mean age of 32.9 ± 4.2 years. 62.1% of the residents felt mood changes after nightly shifts that could adversely affect their daily living, quality of work, and social relationships. The overall prevalence of the use of antidepressant drugs was 20.0% which was significantly higher in women than men. Also, 24.4% of them reported consumption of sedative and hypnotic drugs. 15.6% reported complete healthy status while 9.4% reported partial illness. Complete healthy status was more reported among the residents of anesthesiology and pediatrics while illness was more reported by residents in pathology field. Residents’ satisfaction with their status was positively correlated with the year of residency and marriage, while dissatisfaction was more reported in divorced ones as well as in those with higher number of nightly shifts. Conclusion: Notable number of hospital residents in Iran experience significant stressors and emotional and mental health problems. Among all studies factors type of specialty, year of residency, female gender, number of nightly shifts, and single marital status were more important than other factors.
文摘Analysis Method of ^(131)I Activity in Carbon Cartridge and Internal Dose Assessment for Nuclear Medicine Workers.Shuo Wang1,Fei Tuo1,Jian-feng Zhang1,Xiao-liang Li1,Bao-lu Yang1,Qiang Zhou1,Ze-shu Li1,Shu-ying Kong1,and Wei-hao Qin1(1.National Institute for Radiological Protection,Chinese Center for Disease Control and Prevention,Beijing,100088,China.)
文摘This study links social capital with people’s health and well-being using data from the seventh wave of the World Value Survey,logistic regression,and path analysis.The study’s findings show that happiness and life satisfaction are two different measures of the same construct,or well-being.The determinants of each are also characterised differently:while life satisfaction is more of a stable and relative measure and is more strongly influenced by civic cooperation,social participation,and educational attainment,happiness is more of an unstable measure and is more strongly influenced by community belonging,trust and confidence aggregates,including employment and location of residence of an individual.Moreover,freedom of choice,financial satisfaction or social comparison,and state of health were the most important factors influencing happiness and life satisfaction.The findings also show that self-reported health(SRH)has a greater impact on happiness than a measure of life satisfaction.Path analysis shows out of the three other components of social capital—community belonging,civic engagement,and social participation—trust and confidence aggregates are the ones that have the biggest impact on increased social capital.For both well-being measures,SRH mediated the relationship.The life satisfaction measure had a higher level of mediation of SRH than happiness,but social capital had a smaller direct impact on life satisfaction than on happiness.SRH was found to be partially mediating this relationship for both happiness and life satisfaction measures,which means that people with higher social capital reported feeling better off.
文摘Healthy behavior has long been linked to mental health outcomes.However,the role of artificial intelligence(AI)literacy in shaping healthy behaviors and its potential impact on mental health remains underexplored.This paper presents a scoping review offering a novel perspective on the intersection of healthy behaviors,mental health,and AI literacy.By examining how individuals’understanding of AI influences their choices regarding nutrition and their susceptibility to mental health issues,the current study explores emerging trends in health behavior decision-making.This emphasizes the need for integrating AI literacy into mental health and health behaviors education,as well as the development of AI-driven tools to support healthier behavior choices.It highlights that individuals with low AI literacy may misinterpret or overly depend on AI guidance,resulting in maladaptive health choices,while those with high AI literacy may be more likely to engage reflectively and sustain positive behaviors.The paper outlines the importance of inclusive education,user-centered design,and community-based support systems to enhance AI literacy for digitally marginalized groups.AI literacy may be positioned as a key determinant of health equity,better allowing for interdisciplinary strategies that empower individuals to make informed,autonomous decisions that promote both physical and mental health.
文摘Objective:To systematically sort out the application forms and effects of digital health intervention technologies in oral health management,and provide references for the digital development of stomatology.Methods:By reviewing relevant domestic and foreign studies and clinical practices,this paper summarizes and analyzes the main application forms of digital health interventions,including digital health education,intelligent detection equipment,telemedicine platforms,oral health big data platforms,and school-hospital collaborative screening robots.Results:Studies have shown that digital health interventions can effectively improve the public’s oral health knowledge level,optimize personal health behaviors,enhance clinical diagnosis efficiency,reduce overall medical costs,and promote the innovation and upgrading of oral health management models.Conclusion:Digital health intervention represents an inevitable trend in the future development of stomatology.In the future,it is still necessary to improve data security and privacy protection,technology adaptability and popularity,as well as relevant policies and norms,to give full play to its potential value.
文摘Concerned that fewer than 20%of adolescents meet the World Health Organization(WHO)’s physical activity(PA)guidelines of engaging in≥60 min each day of the week of moderate-to-vigorous PA(MVPA),classifying them as insufficiently active,1 Araujo et al.2 sought to identify the global prevalence of adolescents reporting less frequent MVPA(≥60 min per day of MVPA≥1 days per week)and identify differences in this prevalence by age,gender.
文摘Academic journals,consulting firms,and mainstream media have often published“predictions”about the future develop-ment of medical and health care.These publications often emphasize the potential of cutting-edge scientific or technical breakthroughs.Health Care Science looks at the problem from another perspective.We focus on how these changes enter the health system,how they operate in the real world,and how they reshape the organization and governance of medical services.At the beginning of 2026,we envision the following three major shifts that will reshape healthcare.
文摘Large-scale proteomics studies can refine our understanding of health and disease and enable precision medicine.Here,we provide a detailed atlas of 2,920 plasma proteins linking to diseases(406 prevalent and 660 incident)and 986 health-related traits in 53,026 individuals(median follow-up:14.8 years)from the UK Biobank,representing the most comprehensive proteome profiles to date.This atlas revealed 168,100 protein-disease associations and 554,488 protein-trait associations.
文摘Recently,inflammatory cytokine profiles have been linked to suicide risk in adolescents with non-suicidal self-injury,highlighting a promising biological dimension of suicide risk assessment.Clinical translation of the cytokine profiles into practice will require frontline engagement of the workforce.Mental health nurses are frequently the most accessible professionals in schools,communities,and low-resource settings and are prime candidates to bridge this gap.By integrating psychosocial evaluation with emerging biomarker data,they can deliver systematic risk assessment,continuous monitoring,and timely intervention.This role would not replace psychiatric expertise;it would extend the reach of psychiatric services,embedding suicide prevention across the continuum of care.For health systems,nurse-led integration may enhance capacity,equity,and resilience in responding to adolescent suicide risk.This editorial demonstrates that empowering nurses to operationalize biomarker-informed strategies is needed for advancing effective and sustainable suicide prevention in this vulnerable population.
文摘The accelerating pace of population aging,the rising burden of chronic and non-communicable diseases,the increasing frequency of public health emergencies,and the growing imbalance and structural shortage of global healthcare resources are intensifying challenges.In the field of nursing,in particular,the latest State of the World’s Nursing Report[1]highlights that,although the current global number of nurses is approximately 29.8 million.
基金supported by University Technology Mara(UiTM)under grant number 600-IRMI/FRGS 5/3(273/2019).
文摘Objective:To systematically review the effects of administering metformin and glutathione alone and in coformulation with other compounds on the fertility and reproductive health of diabetic male rodents.Methods:The guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA)were followed to conduct this systematic review.Studies published until August 2024 in PubMed,Web of Science,and Scopus databases were searched,identified,screened,and selected for a detailed review.The keywords included metformin,diabetes,reproduction,glutathione,and rodent models.Results:A total of 166 studies were identified,of which 11 met the inclusion criteria and were included in the qualitative synthesis.One additional study was identified through snowballing and citation tracking,bringing the total to 12 studies.The findings indicate that metformin and glutathione,administered alone or in combination with other compounds,improved sperm count,motility,and morphology;restored reproductive hormone levels;reduced oxidative stress markers;and improved testicular histopathology in diabetic male rodents.Conclusions:Coformulation of metformin and glutathione with other compounds was found to be more effective in improving fertility and reproductive parameters in diabetic male rodents compared to mono-administration.However,further studies on the coformulation of metformin and glutathione are needed to confirm their efficacy and elucidate the underlying mechanisms.Study registration:The study protocol was registered in the International Prospective Register of Systematic Reviews(PROSPERO)with registration number CRD42024561820.
文摘Background:Mental health concerns among doctoral students have become increasingly prominent,with consistently low levels of well-being making this issue a critical focus in higher education research.This study aims to synthesize existing evidence on the mental health and well-being of doctoral students and to identify key factors and intervention strategies reported in the literature.Methods:A systematic review was conducted to examine the determinants and interventions related to doctoral students’mental health and well-being.Relevant studies were comprehensively searched in Web of Science,PubMed,Scopus,and EBSCO,with the final search conducted on September 19,2025.Records were screened according to predefined criteria:empirical studies on doctoral students’mental health or well-being published in English were included,while non-empirical,non-English,and non-doctoral-student-focused studies were excluded.A total of 56 studies were included after rigorous screening.Results:Doctoral students’mental health and well-being are shaped by multiple interacting factors across individual,academic,interpersonal,organizational,and environmental levels.Moreover,variations in gender,identity,discipline,study stage,and institutional context may further exacerbate or mitigate psychological distress.Existing intervention studies primarily focus on three approaches:psychologically oriented training,practice-based behavioral and learning programs,and relationship-or support network-based initiatives.Conclusion:This review offers integrated evidence on doctoral students’mental health and well-being and highlights the need for universities to assume greater responsibility in developing systematic and responsive support mechanisms.Current research remains limited by insufficient cross-cultural comparison,a lack of intersectional perspectives,and a scarcity of large-scale,long-term evaluations of intervention effectiveness.Future studies should give greater attention to institutional contexts and vulnerable groups while expanding the scope and rigor of intervention research.
基金supported by the Fund for Health Promotion from Osaka Prefecture。
文摘Objective:We assessed the risk for physical inactivity due to inadequate health literacy using multivariable analysis in a large middleaged population.Methods:This cross-sectional mail survey using a self-administered questionnaire was conducted in 2020 and included 33,902 community residents aged 40-64 years from 5 cities in Osaka Prefecture,Japan.Of these,12,446(36.7%)agreed to participate in the survey.After exclusion of those with regular visits to medical institutions and those with missing data,the analysis included 3742 participants.Health literacy was measured by the communicative and critical health literacy(CCHL)scale,and participants were classified into 3 groups(low,medium,and high health literacy groups)by the tertiles of the CCHL scale score.Physical inactivity was defined as not completing at least 150 min of moderate-intensity physical activity throughout the week.Results:After adjustment for age,gender,education level,occupation,economic status,living alone,and stages of health behavior change,the multivariable-adjusted odds ratios(ORs)for physical inactivity were 1.36(95% confidence interval[CI]:1.16-1.59,P<0.001)in the medium health literacy group and 1.70(95%CI:1.36-2.11,P<0.001)in the low health literacy group compared with the high health literacy group.Conclusions:This large-scale study provides compelling evidence that those with inadequate health literacy are at higher risk for physical inactivity among middle-aged adults.
基金supported by the National Institutes of Health for the Kansas Center for Metabolism and Obesity Research(award No.P20GM144269)support from the Center for Advancing Translational Sciences of the National Institutes of Health(award No.KL2TR002367)supported by the National Center for Advancing Translational Sciences of the National Institutes of Health(award No.TL1TR002368)。
文摘Overweight and obesity are significant public health concerns worldwide due to their association with many chronic health conditions.This has resulted in the development of various interventions focused on weight loss to reduce the associated health burden.Physical activity is an important lifestyle behavior associated with enhanced health.Evidence supports that many of the benefits of physical activity are realized independent of initial weight status or whether weight loss is achieved,with some benefits additive to what is achieved with weight loss alone.These benefits include enhanced cardiometabolic,brain,cognitive and psychological health,and others.Moreover,in adults with overweight or obesity,physical activity has independent effects on cardiorespiratory fitness,muscular strength,physical function,and mobility.There are also benefits to body composition,with physical activity improving the quality of key tissues,such as skeletal muscle,which may not occur with diet-induced weight loss.Therefore,physical activity is an important public health target for adults with overweight or obesity to provide a wide range of health benefits that extend beyond those of weight loss alone.However,physical activity recommendations and programming efforts should consider the unique characteristics of adults with overweight or obesity to be most effective,and should support a focus on mobility,physical function,and other health outcomes.
文摘Over the past decade,neonicotinoid insecticides have become the fastest-growing and most widely used class of pesticides.Initially,these compounds were considered ideal replacements for more hazardous chemicals such as carbamates and organophosphates,due to their presumed limited impact on the environment and human health.However,neonicotinoids have since been detected in soils,surface waters,groundwater,food,and various human biological samples.Moreover,they have been shown to negatively affect aquatic organisms,including aquatic insects,crustaceans,mollusks,fish,algae/macrophytes,and amphibians.Epidemiological studies and human biomonitoring research have revealed both acute and chronic health effects,ranging from respiratory,cardiovascular,and neurological symptoms to congenital abnormalities.This review examines the effects of neonicotinoids,their ecological consequences,and the potential risks associated with human exposure.
