期刊文献+
共找到13,817篇文章
< 1 2 250 >
每页显示 20 50 100
On the Risks of Medicalization of Adolescents Self-Injuring Acts
1
作者 Inger Ekman Lars Jacobsson 《Open Journal of Psychiatry》 2021年第1期29-46,共18页
Although common among community adolescents, self-injuring acts are mainly studied by psychiatrists and psychologists and rarely by social work researchers. The preponderance of medical research in the field has come ... Although common among community adolescents, self-injuring acts are mainly studied by psychiatrists and psychologists and rarely by social work researchers. The preponderance of medical research in the field has come to associate self-injuring acts with mental issues. This view has to a large extent been adopted among professionals as well as among laypeople. When examining adolescents’ unsolicited internet published narratives, this medicalization of self-injuring acts was found to have negative consequences for disclosure and help-seeking, and hence limit the adolescents’ possibilities to get adequate help and support. The main objective of this work is to study adolescents’ views on hampering factors for help-seeking for self-injuring acts and the role of medicalisation for their willingness for disclosure and help-seeking. Disclosure of self-injuring acts within the social network was described as met with demands to seek professional mental help. Seeking professional help was accompanied with fear of being perceived as crazy or diagnosed as mentally ill. Internet websites were described as value free and safe arenas giving opportunity to disclose self-injuring acts without fear of being stigmatized and labelled as mentally ill. An extended involvement of social work researchers and professionals, approaching self-injuring acts not primarily as a sign of mental problems, but as an adolescent way of trying to manage a complicated social context, could enhance finding adequate support systems. It is also necessary that the medical profession contributes to a demedicalization of self-injuring acts. 展开更多
关键词 self-injuring acts Adolescents Internet Research STIGMA MEDICALIZATION Demedicalization
在线阅读 下载PDF
天麻钩藤饮通过调节TNF-α/STAT3/α1ACT信号通路抑制A1型星型胶质细胞激活减轻血管性痴呆模型大鼠神经元损伤作用机制
2
作者 王小燕 赵敏 +4 位作者 田丰 萧闵 屈楠 刘福贵 刘迟晓 《中国实验方剂学杂志》 北大核心 2026年第7期56-65,共10页
目的:探究天麻钩藤饮对血管性痴呆模型大鼠肿瘤坏死因子-α(TNF-α)/信号转导与转录激活因子3(STAT3)/α1抗胰蛋白酶C末端尾片段(α1ACT)信号通路及A1星型胶质细胞的影响。方法:将72只雄性SD大鼠随机分为假手术组,模型组,天麻钩藤饮高... 目的:探究天麻钩藤饮对血管性痴呆模型大鼠肿瘤坏死因子-α(TNF-α)/信号转导与转录激活因子3(STAT3)/α1抗胰蛋白酶C末端尾片段(α1ACT)信号通路及A1星型胶质细胞的影响。方法:将72只雄性SD大鼠随机分为假手术组,模型组,天麻钩藤饮高、中、低剂量组(5.13、10.26、20.52 g·kg^(-1))及尼莫地平西药组(8.1 mg·kg^(-1)),每组12只。采用永久性双侧颈总动脉闭塞法造模后干预4周。通过新物体识别实验评估学习记忆能力;强迫游泳实验观察行为症状;酶联免疫吸附测定法检测海马组织白细胞介素-6(IL-6)、CC趋化因子配体2(CCL2)水平;尼氏染色观察海马神经元形态;原位末端标记法(TUNEL)染色检测细胞凋亡;免疫组化检测脑源性神经营养因子(BDNF)、胶质纤维酸性蛋白(GFAP)、髓鞘碱性蛋白(MBP)阳性表达;蛋白免疫印迹法(Western blot)测海马组织TNF-α、TNF受体1(TNFR1)、磷酸化(p)-STAT3、α1ACT、IL-6、补体C3、BDNF、S100钙结合蛋白A10(S100A10)、GFAP蛋白表达。结果:与假手术组比较,模型组大鼠新物体相对识别指数显著降低(P<0.01),被动漂浮时间延长、次数显著增多(P<0.01);海马组织IL-6、CCL2表达显著升高(P<0.01),尼氏染色显示神经元数量减少、尼氏小体丢失(P<0.01),MBP阳性表达显著降低(P<0.01),细胞凋亡增多(P<0.01),BDNF阳性表达显著减少(P<0.05),GFAP阳性表达显著升高(P<0.01),TNF-α、TNFR1、p-STAT3、α1ACT、IL-6、补体C3蛋白表达显著升高(P<0.01),BDNF、S100A10显著降低(P<0.01)。与模型组比较,天麻钩藤饮各剂量组新物体相对识别指数明显升高(P<0.05,P<0.01),被动漂浮时间缩短、次数减少(P<0.01),IL-6、CCL2表达显著降低(P<0.05,P<0.01),神经元数量明显增加(P<0.05,P<0.01),MBP阳性表达显著增加(P<0.01),细胞凋亡显著减少(P<0.01),BDNF阳性表达明显增加(P<0.05),GFAP阳性表达显著降低(P<0.01),TNF-α、TNFR1、p-STAT3、α1ACT、IL-6、补体C3蛋白表达降低(P<0.05,P<0.01),BDNF、S100A10蛋白表达显著升高(P<0.01)。结论:天麻钩藤饮治疗可以通过TNF-α/STAT3/α1ACT信号通路抑制血管性痴呆大鼠A1型星型胶质细胞激活,减轻神经元凋亡,提高学习记忆能力。 展开更多
关键词 天麻钩藤饮 血管性痴呆 星型胶质细胞 肿瘤坏死因子-α(TNF-α)/信号转导与转录激活因子3(STAT3)/α1抗胰蛋白酶C末端尾片段(α1act)信号通路
原文传递
On the Strongly Hopfian Acts over Semigroups
3
作者 Ksenya Anatolyevna Kolesnikova Igor Borisovich Kozhukhov 《Applied Mathematics》 2025年第2期183-189,共7页
We find the necessary and sufficient conditions on a coproduct of connected acts over a semigroup to be strongly hopfian. From this, we deduce the conditions of the strong hopfness for unitary acts over groups. Moreov... We find the necessary and sufficient conditions on a coproduct of connected acts over a semigroup to be strongly hopfian. From this, we deduce the conditions of the strong hopfness for unitary acts over groups. Moreover, we prove that a finite coproduct of strongly hopfian acts over an arbitrary semigroup is strongly hopfian. 展开更多
关键词 act Over Semigroup act Over Group Strongly Hopfian act
在线阅读 下载PDF
Deviation of Transitivity in Ba-constructions from the Perspective of Mode and Speech Acts
4
作者 ZHANG Shuo 《Journal of Literature and Art Studies》 2025年第6期460-473,共14页
Ba-constructions carry high level of transitivity,but a deviation towards low transitivity happens.It is found that mode provides axis of this transitivity deviation,especially in spoken dialogue.Under the influence o... Ba-constructions carry high level of transitivity,but a deviation towards low transitivity happens.It is found that mode provides axis of this transitivity deviation,especially in spoken dialogue.Under the influence of irrealis mode,parameters such as aspects,affectedness of O,individuation of O,and affirmation exhibit different degrees of transitivity deviation.Speech acts,which is closely related to mode,are the driving force in discourse of this phenomenon.The composition rules of speech acts of directive,declarative,commitment,and emotive,which account for the majority of speech acts in spoken dialogue,determine that they are all irrealis.Therefore,under the axis of irrealis mode,several transitivity parameters of ba-constructions in oral dialogue deviates towards low transitivity.The phenomenon of deviation of transitivity in ba-constructions verifies transitivity hypothesis. 展开更多
关键词 ba-constructions TRANSITIVITY speech acts MODE
在线阅读 下载PDF
ACTED康复护理联合早期下床活动干预对多发性肋骨骨折术后患者康复进程及疼痛程度的影响
5
作者 黄芳 《黑龙江医药》 2026年第1期232-235,共4页
目的:探讨针对多发性肋骨骨折(MRF)术后患者实施ACTED康复护理+早期下床活动干预的效果。方法:选择黎平县人民医院收治的80例MRF患者(2024年1月—2024年12月),按随机数字表法分为对照组(常规护理)、观察组(ACTED康复护理联合早期下床活... 目的:探讨针对多发性肋骨骨折(MRF)术后患者实施ACTED康复护理+早期下床活动干预的效果。方法:选择黎平县人民医院收治的80例MRF患者(2024年1月—2024年12月),按随机数字表法分为对照组(常规护理)、观察组(ACTED康复护理联合早期下床活动干预),各40例。两组均持续观察至患者出院。对比两组康复进程、疼痛程度、并发症发生情况。结果:观察组康复进程短于对照组,护理后视觉模拟评分表(VAS)评分、并发症发生率均低于对照组,差异有统计学意义(P<0.05)。结论:针对MRF术后患者实施ACTED康复护理联合早期下床活动干预,可减轻术后疼痛,减少并发症的发生,加快康复进程。 展开更多
关键词 多发性肋骨骨折 actED康复护理 早期下床活动 康复进程 疼痛程度
暂未订购
基于ACT-R理论的高中生物学教学策略——以“伴性遗传”为例
6
作者 陈明华 《生物学教学》 北大核心 2026年第1期15-17,共3页
基于ACT-R理论中的产生式系统形成路径对高中生物学“伴性遗传”教学内容进行系统化建构,并通过认知、联结、自动化三个关键环节推动陈述性知识向程序性知识转化,构建个体的产生式、产生式系统,实现知识提升与素养的双重进阶。
关键词 act-R理论 产生式系统 产生式规则 伴性遗传
在线阅读 下载PDF
视觉传播机制ACTS模式——以新闻图像为例 被引量:14
7
作者 宁海林 《西北大学学报(哲学社会科学版)》 CSSCI 北大核心 2012年第3期163-167,共5页
图像在现代传播中发挥越来越大的作用。它看似简单明了,实际上却是一种文化表征,隐含着不少"迷思",把握起来并不容易。本文将图像作为文本,基于符号学理论和阿恩海姆视知觉形式动力理论,提出了视觉传播机制ACTS模式,即从吸引... 图像在现代传播中发挥越来越大的作用。它看似简单明了,实际上却是一种文化表征,隐含着不少"迷思",把握起来并不容易。本文将图像作为文本,基于符号学理论和阿恩海姆视知觉形式动力理论,提出了视觉传播机制ACTS模式,即从吸引注意(Attention)、引向内容(Content)、展现主题(Theme)和积淀为符号(Symbolic)四个层面来解析视觉传播机制,从而在一般意义上揭示了图像从视知觉形式层面到文化意义层面的传播机制。 展开更多
关键词 新闻图像 视觉说服 acts模式
在线阅读 下载PDF
《2024 ESC与欧洲心胸外科协会(EACTS)合作制定的心房颤动管理指南》要点解读 被引量:3
8
作者 黄鹤 石少波 +1 位作者 唐艳红 黄从新 《中国心脏起搏与心电生理杂志》 2024年第5期313-319,共7页
2024年8月30日发布了2024年欧洲心脏病学会(ESC)与欧洲心胸外科协会(EACTS)合作制定的心房颤动(简称房颤)管理指南(下文简称2024 ESC指南)^([1])包含了一系列新的方法和特定治疗建议,以应对全球范围内迅速增长的房颤患者数量。2024 ESC... 2024年8月30日发布了2024年欧洲心脏病学会(ESC)与欧洲心胸外科协会(EACTS)合作制定的心房颤动(简称房颤)管理指南(下文简称2024 ESC指南)^([1])包含了一系列新的方法和特定治疗建议,以应对全球范围内迅速增长的房颤患者数量。2024 ESC指南强调共同决策与平等护理、患者参与、共病管理、循证医学和动态再评估。 展开更多
关键词 心胸外科 循证医学 管理指南 患者参与 心房颤动 欧洲心脏病学会 共同决策 acts
原文传递
具有FACTS控制的EEAC法暂态稳定分析 被引量:3
9
作者 蔡泽祥 申洪 王荔 《电力系统及其自动化学报》 CSCD 2000年第1期45-48,共4页
具有 FACTS控制的 EEAC法暂稳分析的关键是如何在 EEAC的等值系统中计及 FACTS控制的影响。本文将 FACTS对暂态稳定的作用通过对电力系统的串联和关联控制来描述 ,适合于 EEAC各种方法和各类 FACTS控制器。本文基于 EEAC法研究了三种典... 具有 FACTS控制的 EEAC法暂稳分析的关键是如何在 EEAC的等值系统中计及 FACTS控制的影响。本文将 FACTS对暂态稳定的作用通过对电力系统的串联和关联控制来描述 ,适合于 EEAC各种方法和各类 FACTS控制器。本文基于 EEAC法研究了三种典型的 FACTS控制器 (TCSC、STATCON、UPFC)对系统暂态稳定的影响 ,并应用电科院电力系统综合仿真程序进行了校核 ,得到了满意的结果。 展开更多
关键词 电力系统 acts EEAC 暂态稳定
在线阅读 下载PDF
Meaning and the Theory of Speech Acts
10
作者 孙丽 吴小梅 《语言与文化研究》 2008年第2期43-46,共4页
According to J.L.Austin and J.R.Searle Speech Act Theory,many actions can actually be performed with words that is to say an important part of the meaning of an utterance is what that utterance does.Language is not on... According to J.L.Austin and J.R.Searle Speech Act Theory,many actions can actually be performed with words that is to say an important part of the meaning of an utterance is what that utterance does.Language is not only used to inform or describe things,it is often used to "do things".The utterances are of three kinds of acts:Locutionary Act,Illocutionary Act,and Perlocutionary Act which are performed simultaneously.Through the study,we see that speech can be far beyond the level of language system. 展开更多
关键词 utterance act MEANING
原文传递
A Review of Indirect Speech Acts in Speech Act Theory
11
作者 张焕芹 《海外英语》 2018年第11期234-235,共2页
The theory of indirect speech acts proposed by John Searle is a problematic issue in speech act theory. The theory is subject to various criticisms.This essay reviews various arguments and the significant problems wit... The theory of indirect speech acts proposed by John Searle is a problematic issue in speech act theory. The theory is subject to various criticisms.This essay reviews various arguments and the significant problems with reference to the indirect speech acts. The review includes some important concepts of speech act theory which are related to indirect speech acts; inference theory and idiom theory which underline indirect speech acts and their major problems in accounting for indirect speech acts. 展开更多
关键词 speech act indirect speech speech act theory
在线阅读 下载PDF
ACTS数据有效性检验算法仿真
12
作者 樊晓光 李建勋 +1 位作者 丛伟 樊蓉 《电讯技术》 北大核心 2010年第5期1-7,共7页
为解决空战训练系统飞行数据在实时传输过程中的数据延时、丢失和错误等问题,搭建了一种空战训练系统(ACTS)数据有效性检验算法仿真实验环境,采用两台PC和两部电台来进行收发飞行数据的模拟,并利用某型飞机的试飞数据对设计的数据有效... 为解决空战训练系统飞行数据在实时传输过程中的数据延时、丢失和错误等问题,搭建了一种空战训练系统(ACTS)数据有效性检验算法仿真实验环境,采用两台PC和两部电台来进行收发飞行数据的模拟,并利用某型飞机的试飞数据对设计的数据有效性检验算法进行了验证,实现了地面监控系统对空中态势的实时显示和评估。 展开更多
关键词 空战训练系统 飞行数据 数据有效性 检验算法 仿真
在线阅读 下载PDF
视觉表征ACTS模式下的华为海外宣传片研究
13
作者 聂丹 《西部广播电视》 2017年第16期115-116,共2页
随着经济全球化的快速发展,品牌形象成为一个企业利益的重要体现。广告宣传片是解读和阐释品牌形象的直接途径。由于宣传片具备影像制作的众多优势,可以极大地推广某一品牌,因此各大企业都越来越重视广告宣传片的制作和传播。本文以华... 随着经济全球化的快速发展,品牌形象成为一个企业利益的重要体现。广告宣传片是解读和阐释品牌形象的直接途径。由于宣传片具备影像制作的众多优势,可以极大地推广某一品牌,因此各大企业都越来越重视广告宣传片的制作和传播。本文以华为海外宣传片Dream It Possible为例,运用视觉表征ACTS模式,对其进行视觉阐释,分析其文本蕴含的深层意义。 展开更多
关键词 视觉表征acts模式 广告宣传片 DreamItPossibl
在线阅读 下载PDF
基于ACTS的学校教学网格化管理策略初探
14
作者 李蓓 《教育科学论坛》 2016年第10期23-27,共5页
ACTS是英文全称Ability and Competence Test System的首字母缩写,中文名称为"学业素质与能力评价系统"。这一科学的评价系统引入学校已近三年,经历了从完全陌生到被动认知再到主动认同和科学使用的过程。学校通过不断学习、培训、研... ACTS是英文全称Ability and Competence Test System的首字母缩写,中文名称为"学业素质与能力评价系统"。这一科学的评价系统引入学校已近三年,经历了从完全陌生到被动认知再到主动认同和科学使用的过程。学校通过不断学习、培训、研究、讨论和运用,逐渐探索出基于ACTS的网格化教学管理体系,以评促教,让管理更加科学精细,让教学更为有效针对。三年历程中, 展开更多
关键词 网格化管理 acts 科学的评价 评价系统 COMPETENCE 学习类型 教导主任 三年 课堂研究 多元智能理论
原文传递
LncRNA MEG3 acts a biomarker and regulates cell functions by targeting ADAR1 in colorectal cancer 被引量:14
15
作者 Wei Wang Ying Xie +4 位作者 Fei Chen Xu Liu Li-Li Zhong Hai-Qiang Wang Qing-Chang Li 《World Journal of Gastroenterology》 SCIE CAS 2019年第29期3972-3984,共13页
BACKGROUND Colorectal cancer (CRC) is the third most prevalent malignancy and has the fourth highest global cancer mortality rate. Early diagnosis and prompt medical attention can improve quality of life and the progn... BACKGROUND Colorectal cancer (CRC) is the third most prevalent malignancy and has the fourth highest global cancer mortality rate. Early diagnosis and prompt medical attention can improve quality of life and the prognosis of CRC patients. Accumulating evidence reveals that long non-coding RNAs (lncRNAs) function as oncogenes or anti-oncogenes, as well as biomarkers in various cancers. AIM To investigate the levels and molecular mechanism of the lncRNA maternally expressed gene 3 (MEG3) in CRC. METHODS The levels of lncRNA MEG3 in CRC tissue, serum and cell line samples were explored via qRT-PCR. The relationship between MEG3 levels and clinicopathological features in CRC was investigated. The diagnostic and prognostic values of serum MEG3 levels were analyzed with ROC curves and KaplanMeier survival curves, respectively. RESULTS Significant decreased levels of MEG3 existed in CRC tissue, cell lines and serum. CRC patients with down-regulated serum MEG3 levels had larger tumor sizes, and advanced clinical stages. The sensitivity and specificity of serum MEG3 levels in CRC detection was 0.667 and 0.875, respectively. Tumor size, T stages, and serum MEG3 levels are indie factors that produce an effect on CRC patients' prognosis. KaplanMeier survival curves suggested that CRC patients with high levels of MEG3 had a remarkably better overall survival rate. CONCLUSION LncRNA MEG3 is down-regulated in CRC, and regulates cell functions by targeting adenosine deaminase’s effect on RNA 1 in CRC. 展开更多
关键词 LncRNA Maternally EXPRESSED gene 3 BIOMARKER Colorectal cancer ADENOSINE DEAMINASE acting on RNA 1
暂未订购
A review of speech Acts
16
作者 区莹 《科技信息》 2010年第32期170-171,共2页
Pragmatics is a relatively new subject compared with other linguistic studies.In this paper,we will review the definition of pragmatics and its scope.Then a detailed review of speech acts will be shown in the second p... Pragmatics is a relatively new subject compared with other linguistic studies.In this paper,we will review the definition of pragmatics and its scope.Then a detailed review of speech acts will be shown in the second part of the paper.It is mainly about many aspects of speech acts,such as its definition,classification,felicity conditions and so on.The last part of the paper is the prospects of application of pragmatics. 展开更多
关键词 英语教学 教学方法 英语语义 语用学
在线阅读 下载PDF
密旋链霉菌Act12对土壤养分和微生物群落的影响 被引量:1
17
作者 刘逸 师子繁 +3 位作者 高晓怡 刘延 郭俏 来航线 《西北农林科技大学学报(自然科学版)》 北大核心 2025年第10期144-153,168,共11页
【目的】探究密旋链霉菌(Streptomyces pactum)Act12对土壤养分和微生物群落结构的影响,为Act12应用于农业生产提供参考。【方法】选取陕西杨凌种植玉米的农田土壤为材料,采用室内培养试验,设置CK(未经Act12处理)和T(Act12处理)2个处理... 【目的】探究密旋链霉菌(Streptomyces pactum)Act12对土壤养分和微生物群落结构的影响,为Act12应用于农业生产提供参考。【方法】选取陕西杨凌种植玉米的农田土壤为材料,采用室内培养试验,设置CK(未经Act12处理)和T(Act12处理)2个处理组,测定Act12在土壤中的定殖情况,分析培养30 d时CK和T组土壤pH及养分含量,然后利用PCR扩增技术分析CK和T组土壤微生物多样性和群落组成变化。最后通过物种差异类别分析(Lefse)和网络拓扑结构分析,研究CK与T组土壤微生物群落结构差异。【结果】随着培养时间的延长,Act12含量呈先增加后降低趋势,其中培养15 d时土壤Act12含量最高,为4×10^(6) CFU/g。与CK相比,T组土壤有效硫、有效铁、有效锰含量显著增加,增幅分别为29.45%,5.07%,9.68%;交换性钙含量显著减少7.05%。与CK相比,T组土壤微生物群落多样性无显著差异,门水平上相对丰度排前5的微生物种类未变,但占比发生了变化;属水平上相对丰度排前5的微生物种类发生了变化。Lefse结果显示,与CK相比,T组土壤贪铜菌属、变球菌属、浮微菌属等属微生物显著上调,溶杆菌属、甲基芽胞杆菌属、湖杆菌属等属微生物显著下调。微生物网络拓扑结构分析结果显示,与CK相比,T组网络模块化指数增加89.02%,明显提高了微生物系统的稳定性。【结论】密旋链霉菌Act12影响了土壤养分含量,改变微生物群落组成,并提高土壤微生物群落的稳定性,这均与Act12的次生代谢物密切相关。 展开更多
关键词 密旋链霉菌act12 土壤养分 微生物群落结构
在线阅读 下载PDF
An Interpretation of“Is He Living or Is He Dead”——From the Perspective of the Speech Acts Theory of Pragmatics
18
作者 霍兴 《海外英语》 2013年第9X期241-242,246,共3页
Speech acts theory has been widely studied in linguistics, but applied into analyzing literature works has been very few. This paper interprets Mark Twain's short novel "Is He Living or Is He Dead" from ... Speech acts theory has been widely studied in linguistics, but applied into analyzing literature works has been very few. This paper interprets Mark Twain's short novel "Is He Living or Is He Dead" from the perspective of the speech acts theory of pragmatics. 展开更多
关键词 locutionary act illocutionary act perlocutionary a
在线阅读 下载PDF
The Necessity of Teaching Pragmatic Skills and Speech Acts in L2 Classroom
19
作者 陈瑶瑶 《海外英语》 2012年第5X期274-275,279,共3页
The current article mainly focuses on identifying pragmatic skills and speech acts,along with illustrating pragmatic failures in sec ond language learners.On the other hand,a brief discussion of the necessity of teach... The current article mainly focuses on identifying pragmatic skills and speech acts,along with illustrating pragmatic failures in sec ond language learners.On the other hand,a brief discussion of the necessity of teaching pragmatic skills and speech acts is provided. 展开更多
关键词 PRAGMATIC SKILLS speech acts failure TEACHING
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部