In this paper,the host-vip interaction of cucurbit[7]uril(Q[7]) and chromone(CMO) has been developed as a fluorescent probe for the highly selective detection of Zn2+ and Cd^(2+) in water based on a chelation-enhanc...In this paper,the host-vip interaction of cucurbit[7]uril(Q[7]) and chromone(CMO) has been developed as a fluorescent probe for the highly selective detection of Zn2+ and Cd^(2+) in water based on a chelation-enhanced fluorescence(CHEF) mechanism.There was a good linear relationship between the fluorescence intensity of the CMO@Q[7] probe and the concentration of Zn^(2+ )or Cd^(2+) in the range of 0-3.0×10^(-5) mol/L and the detection limit for Zn^(2+) and Cd2+ was found to be 2.03×10^(-6) mol/L and 1.89×10^(-6)mol/L,respectively.The X-ray crystal structure indicated that different coordination fashions were triggered by Zn^(2+) and Cd^(2+ )in the CMO@Q[7] complexes,respectively.However,both metal ions coordinated with the carbonyl oxygen of CMO,which was encapsulated in the cavity of Q[7],thus leading to the enhancement of recognition fluorescence emission of CMO.展开更多
A simple ＂off-on＂ fluorescent chemosensor with high selectivity to zinc ions based on 1,10-phenanthro-line receptor dipyrido[3,2-d：2＇,3＇-f]quinoxaline（L） was investigated.The selectivity response of receptor L ...A simple ＂off-on＂ fluorescent chemosensor with high selectivity to zinc ions based on 1,10-phenanthro-line receptor dipyrido[3,2-d：2＇,3＇-f]quinoxaline（L） was investigated.The selectivity response of receptor L to zinc ion was demonstrated by UV-Vis absorption and fluorescence spectroscopies in DMF buffer solution.The experiment results show that the fluorescent chemosensor L exhibits the optimum response behavior to Zn2＋ in the range of pH 8.0―9.0 and shows excellent selectivity to Zn2＋ over other cations tested.展开更多
Nitrofuran antibiotics threaten human health and the environment due to their toxicity and persistence.Their detection is challenging due to low concentrations and interference,while fluorescence sensing offers superi...Nitrofuran antibiotics threaten human health and the environment due to their toxicity and persistence.Their detection is challenging due to low concentrations and interference,while fluorescence sensing offers superior sensitivity and selectivity for effective monitoring.In this work,a novel halogen-bonded organic framework,XOF-TPEM,was introduced,constructed using an imidazole-based ligand AIE molecule,TPEM.The framework was successfully characterized by various techniques,including 1H NMR,PXRD,XPS,FT-IR,HRTEM,SAED,SEM and EDS,confirming its excellent crystalline structure.As TPEM is an electron-donating AIE fluorophore,the fluorescent XOF-TPEM demonstrates potential as a selective sensor for electron-deficient nitrofuran antibiotics.Experimental results show that it exhibits high sensitivity and selectivity for detecting nitrofurans such as NFT,FZD,FLD,and NFZ,with LODs of 9.7 ppb,11.0 ppb,19.7 ppb,and 236.1 ppb,respectively.Mechanistic studies indicate that the outstanding fluorescence detection performance is attributed to the inner-filter effect occurring between XOF-TPEM and the nitrofuran antibiotics.Through comparison with the sensing performance of a pyridine-based XOF,the superiority of imidazole ligands in constructing XOFs is demonstrated.This study presents a novel luminescent halogen-bonded organic framework and highlights the superiority of imidazole-based halogen-bonded organic frameworks,underscoring their significant potential for expanding their functional applications.展开更多
Cobalt phthalocyanine-graphene （CoPc-Gr） complex are fabricated through 7r-Tr interaction of each components, with CoPc adsorbed/inserted on/in the graphene sheets. The obtained complex could be used in the electro-...Cobalt phthalocyanine-graphene （CoPc-Gr） complex are fabricated through 7r-Tr interaction of each components, with CoPc adsorbed/inserted on/in the graphene sheets. The obtained complex could be used in the electro-chemical detection of various medicines. CoPc-Gr modified glassy electrode shows excellent response to the electro-oxidation of dopamine （DA） and ascorbic acid （AA）, much better than those of CoPc, graphene oxide （GrO） or graphene （Gr） modified electrode. Significantly, the detection of dopamine is a diffusion-controlled process, highly selective, and has a low detection limit and broad linear range.展开更多
The aluminum based MOFs compound, MIL-96(Al), has been studied as a luminescence sensor by incorporating of Eu3+ ions, which renders the compound strong red-light emission. The as-synthesized MIL-96(Al):Eu3+ nanocryst...The aluminum based MOFs compound, MIL-96(Al), has been studied as a luminescence sensor by incorporating of Eu3+ ions, which renders the compound strong red-light emission. The as-synthesized MIL-96(Al):Eu3+ nanocrystals exhibit water dispersibility and environmental stability, which are general requirement for an ideal sensing material. The MIL-96(Al):Eu3+ nanocrystals show excellent selective detection ability on Fe3+ ions in aqueous solution with value of low detection limit 20 μM. Meanwhile, it also exhibits excellent selective detection ability on CrO42- and Cr2O72- in aqueous solution with value of low detection limit 10 and 22 μM, respectively. The results of this study show that MIL-96(Al):Eu3+ nanocrystals could be used as a multi-responsive luminescent senor for Fe3+ and Cr(Ⅵ) species in aqueous solution. The possible luminescence quenching mechanism has also been discussed.展开更多
Detection of trace-level hydrogen sulfide(H2 S)gas is of great importance whether in industrial production or disease diagnosis.This research presents a novel H2 S gas sensor based on integrated resonant dual-microcan...Detection of trace-level hydrogen sulfide(H2 S)gas is of great importance whether in industrial production or disease diagnosis.This research presents a novel H2 S gas sensor based on integrated resonant dual-microcantilevers which can identify and detect trace-level H2 S in real-time.The sensor consists of two integrated resonant microcantilever sensors with different functions.One cantilever sensor can identify H2 S by outputting positive frequency shift signals,while the other cantilever sensor will detect H2 S as a normally used cantilever sensor with negative frequency shifts.Combined the two cantilever sensors,the proposed gas sensor can distinguish H2 S from a variety of common gases,and the detection limit to H2 S of the sensor is as sensitive as below 1 ppb.展开更多
Domesticated sheep have been exposed to artificial selection for the production of fiber, meat, and milk as well as to natural selection. Such selections are likely to have imposed distinctive selection signatures on ...Domesticated sheep have been exposed to artificial selection for the production of fiber, meat, and milk as well as to natural selection. Such selections are likely to have imposed distinctive selection signatures on the sheep genome. Therefore, detecting selection signatures across the genome may help elucidate mechanisms of selection and pinpoint candidate genes of interest for further investigation. Here, detection of selection signatures was conducted in three sheep breeds, Sunite （n=66）, German Mutton （n=159）, and Dorper （n=93）, using the Illumina OvineSNP50 Genotyping BeadChip array. Each animal provided genotype information for 43 273 autosomal single nucleotide polymorphisms （SNPs）. We adopted two complementary haplotype-based statistics of relative extended haplotype homozygosity （REHH） and the cross-popu- lation extended haplotype homozygosity （XP-EHH） tests. In total, 707,755, and 438 genomic regions subjected to positive selection were identified in Sunite, German Mutton, and Dorper sheep, respectively, and 42 of these regions were detected using both REHH and XP-EHH analyses. These genomic regions harbored many important genes, which were enriched in gene ontology terms involved in muscle development, growth, and fat metabolism. Fourteen of these genomic regions overlapped with those identified in our previous genome-wide association studies, further indicating that these genes under positive selection may underlie growth developmental traits. These findings contribute to the identification of candidate genes of interest and aid in understanding the evolutionary and biological mechanisms for controlling complex traits in Chinese and western sheep.展开更多
A novel and simple cyanide chemosensor 2-（naphthalen-1-ylmethylene）malononitrile（L） was designed and synthesized via a green chemistry method in water without using any catalyst.The chemosensor showed an excellent...A novel and simple cyanide chemosensor 2-（naphthalen-1-ylmethylene）malononitrile（L） was designed and synthesized via a green chemistry method in water without using any catalyst.The chemosensor showed an excellent sensitivity and selectivity for CN in aqueous solution.The detection limit could be as low as 1.6×10~7 moI/L（0.16μmol/L）,which is far lower than the WHO guideline of 1.9μmol/L cyanide for drink water.展开更多
A chemometric method to determine selective ion by using non-negative immune algorithm （NNIA） was proposed. In the method, the mutual projections of the chromatographic profiles at different m/z channel are calculat...A chemometric method to determine selective ion by using non-negative immune algorithm （NNIA） was proposed. In the method, the mutual projections of the chromatographic profiles at different m/z channel are calculated using NNIA. Suppose a GC-MS data with m retention time points and n mass channels, the projections of the GC-MS data onto a chromatographic profile at a mass channel will form a mass spectrum of ln vector. If the chromatographic profile at a selective mass channel is used, the extracted mass spectrum will be a correct one. Therefore, by comparing the extracted mass spectrum with a reference spectrum, the selective ion can be identified, and the corresponding chromatographic profile can be obtained at the same time. GC-MS data of 40-pesticide mixture was investigated by the method. The results show that both the mass spectral and the chromatographic information of the interested components can be extracted from the overlapping signals, except for the special cases of isomeric components with very similar mass spectra.展开更多
Non-uniform step-size distribution is implemented for split-step based nonlinear compensation in singlechannel 112-Gb/s 16 quadrature amplitude modulation （QAM） transmission. Numerical simulations of the system incl...Non-uniform step-size distribution is implemented for split-step based nonlinear compensation in singlechannel 112-Gb/s 16 quadrature amplitude modulation （QAM） transmission. Numerical simulations of the system including a 20 × 80 km uncompensated link are performed using logarithmic step size distribution to compensate signal distortions. 50% of reduction in number of steps with respect to using constant step sizes is observed. The performance is further improved by optimizing nonlinear calculating position （NLCP） in case of using constant step sizes while NLCP optimization becomes unnecessary when using logarithmic step sizes, which reduces the computational effort due to uniformly distributed nonlinear phase for all successive steps.展开更多
基金support from the Science and Technology Support Plan of Guizhou Province [Guizhou Science and Technology Cooperation Support (2020) 4Y218]。
文摘In this paper,the host-vip interaction of cucurbit[7]uril(Q[7]) and chromone(CMO) has been developed as a fluorescent probe for the highly selective detection of Zn2+ and Cd^(2+) in water based on a chelation-enhanced fluorescence(CHEF) mechanism.There was a good linear relationship between the fluorescence intensity of the CMO@Q[7] probe and the concentration of Zn^(2+ )or Cd^(2+) in the range of 0-3.0×10^(-5) mol/L and the detection limit for Zn^(2+) and Cd2+ was found to be 2.03×10^(-6) mol/L and 1.89×10^(-6)mol/L,respectively.The X-ray crystal structure indicated that different coordination fashions were triggered by Zn^(2+) and Cd^(2+ )in the CMO@Q[7] complexes,respectively.However,both metal ions coordinated with the carbonyl oxygen of CMO,which was encapsulated in the cavity of Q[7],thus leading to the enhancement of recognition fluorescence emission of CMO.
基金Supported by the Talent-supporting Program Foundation of Liaoning Province,China(No.2009R03)the Science Foundation of Education Office of Liaoning Province,China(No.2009A028)
文摘A simple ＂off-on＂ fluorescent chemosensor with high selectivity to zinc ions based on 1,10-phenanthro-line receptor dipyrido[3,2-d：2＇,3＇-f]quinoxaline（L） was investigated.The selectivity response of receptor L to zinc ion was demonstrated by UV-Vis absorption and fluorescence spectroscopies in DMF buffer solution.The experiment results show that the fluorescent chemosensor L exhibits the optimum response behavior to Zn2＋ in the range of pH 8.0―9.0 and shows excellent selectivity to Zn2＋ over other cations tested.
基金supported by National Natural Science Foundation of China(22371218,21702153,52270070 and 21801194)Wuhan Science and Technology Bureau(whkxjsjoo9)support of the Core Facility of Wuhan University and the Large-scale Instrument and Equipment Sharing Foundation of Wuhan University。
文摘Nitrofuran antibiotics threaten human health and the environment due to their toxicity and persistence.Their detection is challenging due to low concentrations and interference,while fluorescence sensing offers superior sensitivity and selectivity for effective monitoring.In this work,a novel halogen-bonded organic framework,XOF-TPEM,was introduced,constructed using an imidazole-based ligand AIE molecule,TPEM.The framework was successfully characterized by various techniques,including 1H NMR,PXRD,XPS,FT-IR,HRTEM,SAED,SEM and EDS,confirming its excellent crystalline structure.As TPEM is an electron-donating AIE fluorophore,the fluorescent XOF-TPEM demonstrates potential as a selective sensor for electron-deficient nitrofuran antibiotics.Experimental results show that it exhibits high sensitivity and selectivity for detecting nitrofurans such as NFT,FZD,FLD,and NFZ,with LODs of 9.7 ppb,11.0 ppb,19.7 ppb,and 236.1 ppb,respectively.Mechanistic studies indicate that the outstanding fluorescence detection performance is attributed to the inner-filter effect occurring between XOF-TPEM and the nitrofuran antibiotics.Through comparison with the sensing performance of a pyridine-based XOF,the superiority of imidazole ligands in constructing XOFs is demonstrated.This study presents a novel luminescent halogen-bonded organic framework and highlights the superiority of imidazole-based halogen-bonded organic frameworks,underscoring their significant potential for expanding their functional applications.
基金supported by the National Natural Science Foundation of China (Grant No. 20773121 and No. 21176221)the National Basic Research in "Climbing" Program of China (Grant No. 2011CB201402)
文摘Cobalt phthalocyanine-graphene （CoPc-Gr） complex are fabricated through 7r-Tr interaction of each components, with CoPc adsorbed/inserted on/in the graphene sheets. The obtained complex could be used in the electro-chemical detection of various medicines. CoPc-Gr modified glassy electrode shows excellent response to the electro-oxidation of dopamine （DA） and ascorbic acid （AA）, much better than those of CoPc, graphene oxide （GrO） or graphene （Gr） modified electrode. Significantly, the detection of dopamine is a diffusion-controlled process, highly selective, and has a low detection limit and broad linear range.
基金Supported by the Natural Science Foundation of Fujian Province (2017J01746)National Natural Science Foundation of China (51972061)。
文摘The aluminum based MOFs compound, MIL-96(Al), has been studied as a luminescence sensor by incorporating of Eu3+ ions, which renders the compound strong red-light emission. The as-synthesized MIL-96(Al):Eu3+ nanocrystals exhibit water dispersibility and environmental stability, which are general requirement for an ideal sensing material. The MIL-96(Al):Eu3+ nanocrystals show excellent selective detection ability on Fe3+ ions in aqueous solution with value of low detection limit 20 μM. Meanwhile, it also exhibits excellent selective detection ability on CrO42- and Cr2O72- in aqueous solution with value of low detection limit 10 and 22 μM, respectively. The results of this study show that MIL-96(Al):Eu3+ nanocrystals could be used as a multi-responsive luminescent senor for Fe3+ and Cr(Ⅵ) species in aqueous solution. The possible luminescence quenching mechanism has also been discussed.
基金supported by National Key R&D Program of China(No.2016YFA0200800)National Natural Science Foundation of China(NSFC,Nos.61874130,61604163,61527818,61604162)+1 种基金Key Research Program of Frontier Sciences of Chinese Academy of Sciences(No.QYZDJ-SSW-JSC001)the financial support of the Youth Innovation Promotion Association CAS(No.2017278)。
文摘Detection of trace-level hydrogen sulfide(H2 S)gas is of great importance whether in industrial production or disease diagnosis.This research presents a novel H2 S gas sensor based on integrated resonant dual-microcantilevers which can identify and detect trace-level H2 S in real-time.The sensor consists of two integrated resonant microcantilever sensors with different functions.One cantilever sensor can identify H2 S by outputting positive frequency shift signals,while the other cantilever sensor will detect H2 S as a normally used cantilever sensor with negative frequency shifts.Combined the two cantilever sensors,the proposed gas sensor can distinguish H2 S from a variety of common gases,and the detection limit to H2 S of the sensor is as sensitive as below 1 ppb.
基金supported by the National Natural Science Foundation of China (31200927)the National Modern Agricultural Industry Technology Fund for Scientists in the Sheep Industry System of China (CARS-39-04B)the Agricultural Science and Technology Innovation Program, China (ASTIP-IAS-TS-6)
文摘Domesticated sheep have been exposed to artificial selection for the production of fiber, meat, and milk as well as to natural selection. Such selections are likely to have imposed distinctive selection signatures on the sheep genome. Therefore, detecting selection signatures across the genome may help elucidate mechanisms of selection and pinpoint candidate genes of interest for further investigation. Here, detection of selection signatures was conducted in three sheep breeds, Sunite （n=66）, German Mutton （n=159）, and Dorper （n=93）, using the Illumina OvineSNP50 Genotyping BeadChip array. Each animal provided genotype information for 43 273 autosomal single nucleotide polymorphisms （SNPs）. We adopted two complementary haplotype-based statistics of relative extended haplotype homozygosity （REHH） and the cross-popu- lation extended haplotype homozygosity （XP-EHH） tests. In total, 707,755, and 438 genomic regions subjected to positive selection were identified in Sunite, German Mutton, and Dorper sheep, respectively, and 42 of these regions were detected using both REHH and XP-EHH analyses. These genomic regions harbored many important genes, which were enriched in gene ontology terms involved in muscle development, growth, and fat metabolism. Fourteen of these genomic regions overlapped with those identified in our previous genome-wide association studies, further indicating that these genes under positive selection may underlie growth developmental traits. These findings contribute to the identification of candidate genes of interest and aid in understanding the evolutionary and biological mechanisms for controlling complex traits in Chinese and western sheep.
基金supported by the National Natural Science Foundation of China(NSFC)(Nos.21064006,21161018, 21262032)the Natural Science Foundation of Gansu Province (No.1010RJZA018)the Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China(No.IRT1177)
文摘A novel and simple cyanide chemosensor 2-（naphthalen-1-ylmethylene）malononitrile（L） was designed and synthesized via a green chemistry method in water without using any catalyst.The chemosensor showed an excellent sensitivity and selectivity for CN in aqueous solution.The detection limit could be as low as 1.6×10~7 moI/L（0.16μmol/L）,which is far lower than the WHO guideline of 1.9μmol/L cyanide for drink water.
基金financially supported by the National Natural Science Foundation of China (21175074)
文摘A chemometric method to determine selective ion by using non-negative immune algorithm （NNIA） was proposed. In the method, the mutual projections of the chromatographic profiles at different m/z channel are calculated using NNIA. Suppose a GC-MS data with m retention time points and n mass channels, the projections of the GC-MS data onto a chromatographic profile at a mass channel will form a mass spectrum of ln vector. If the chromatographic profile at a selective mass channel is used, the extracted mass spectrum will be a correct one. Therefore, by comparing the extracted mass spectrum with a reference spectrum, the selective ion can be identified, and the corresponding chromatographic profile can be obtained at the same time. GC-MS data of 40-pesticide mixture was investigated by the method. The results show that both the mass spectral and the chromatographic information of the interested components can be extracted from the overlapping signals, except for the special cases of isomeric components with very similar mass spectra.
基金funding of the Erlangen Graduate School in Advanced Optical Technologies (SAOT) by the German National Science Foundation(DFG) in the framework of the excellence initiative
文摘Non-uniform step-size distribution is implemented for split-step based nonlinear compensation in singlechannel 112-Gb/s 16 quadrature amplitude modulation （QAM） transmission. Numerical simulations of the system including a 20 × 80 km uncompensated link are performed using logarithmic step size distribution to compensate signal distortions. 50% of reduction in number of steps with respect to using constant step sizes is observed. The performance is further improved by optimizing nonlinear calculating position （NLCP） in case of using constant step sizes while NLCP optimization becomes unnecessary when using logarithmic step sizes, which reduces the computational effort due to uniformly distributed nonlinear phase for all successive steps.
