Alternating pulses current - chronopotentiometric stripping analysis (APC-CPSA) is a new method as a variant of chronopotentiometric stripping analysis (CPSA). During the stripping step an alternating pulse current wi...Alternating pulses current - chronopotentiometric stripping analysis (APC-CPSA) is a new method as a variant of chronopotentiometric stripping analysis (CPSA). During the stripping step an alternating pulse current with a high frequency in a square wave mode is imposed on the electrode system. Thus, tau and sensitivity of APC-CPSA is increased a lot. The tau, E similar to t equation and its reciprocal derivative equation for APC-CPSA are derived and verified by the experimental results.展开更多
This paper studies the problem of tensor principal component analysis (PCA). Usually the tensor PCA is viewed as a low-rank matrix completion problem via matrix factorization technique, and nuclear norm is used as a c...This paper studies the problem of tensor principal component analysis (PCA). Usually the tensor PCA is viewed as a low-rank matrix completion problem via matrix factorization technique, and nuclear norm is used as a convex approximation of the rank operator under mild condition. However, most nuclear norm minimization approaches are based on SVD operations. Given a matrix , the time complexity of SVD operation is O(mn2), which brings prohibitive computational complexity in large-scale problems. In this paper, an efficient and scalable algorithm for tensor principal component analysis is proposed which is called Linearized Alternating Direction Method with Vectorized technique for Tensor Principal Component Analysis (LADMVTPCA). Different from traditional matrix factorization methods, LADMVTPCA utilizes the vectorized technique to formulate the tensor as an outer product of vectors, which greatly improves the computational efficacy compared to matrix factorization method. In the experiment part, synthetic tensor data with different orders are used to empirically evaluate the proposed algorithm LADMVTPCA. Results have shown that LADMVTPCA outperforms matrix factorization based method.展开更多
The predominant causal agent of poplar leaf blight is the pathogenic fungus Alternaria alternata (Fr.) Keissl., which exhibits host specificity toward Populus species. To elucidate the molecular response mechanisms of...The predominant causal agent of poplar leaf blight is the pathogenic fungus Alternaria alternata (Fr.) Keissl., which exhibits host specificity toward Populus species. To elucidate the molecular response mechanisms of A. alternata under fludioxonil fungicide stress, the fungus was cultured at the half-maximal effective concentration (EC₅₀) of fludioxonil. Transcriptomic and metabolomic profiles were analyzed using mycelia harvested under these conditions. Comparative analysis revealed 1,001 differentially expressed genes (DEGs) in the resistant strain (RS) relative to the wild-type strain (WT), comprising 628 upregulated and 373 downregulated genes. Concurrently, 524 differentially accumulated metabolites (DAMs) were identified, with 336 upregulated and 188 downregulated metabolites. KEGG pathway enrichment demonstrated pronounced upregulation in glycerophospholipid metabolism, α-linolenic acid metabolism, nucleic acid biosynthesis, and glycosylation processes. Conversely, arachidonic acid and galactose metabolism pathways were suppressed. Significant downregulation was observed in phosphatidylinositol signaling, aflatoxin biosynthesis, and cutin/suberin/wax biosynthesis pathways. Transcriptomic profiling further indicated that upregulated DEGs were predominantly associated with amino sugar/nucleotide sugar metabolism, ABC transporters, aflatoxin biosynthesis, and purine metabolism, while downregulated DEGs were enriched in N-glycan biosynthesis, endoplasmic reticulum protein processing, steroid biosynthesis, and riboflavin metabolism. Fludioxonil exerted substantial inhibitory effects on fungal growth, pathogenicity, and metabolic activity. Mechanistically, A. alternata counteracted fungicide-induced stress through modulation of its antioxidant defense system. This integrative multi-omics study delineates the dynamic gene expression and metabolic reprogramming in A. alternata under fludioxonil exposure, providing novel insights into potential molecular targets and informing the development of next-generation fungicidal strategies for phytopathogen control.展开更多
Alternate wetting and soil drying irrigation(AWD)technique is crucial in infuencing grain quality in rice(Oryza sativa L.).Lipids are the third most abundant constituents in rice grains,after starch and proteins,and a...Alternate wetting and soil drying irrigation(AWD)technique is crucial in infuencing grain quality in rice(Oryza sativa L.).Lipids are the third most abundant constituents in rice grains,after starch and proteins,and are closely related to grain quality.However,it remains unclear about the changes in lipids profling under different AWD regimes.This study set up three irrigation regimes including conventional irrigation(CI),alternate wetting and moderate soil drying irrigation(AWMD),and alternate wetting and severe soil drying irrigation(AWSD).It explored lipidome changes in milled rice of Yangdao 6(YD6)using the untargeted lipidomics approach and analyzed rice cooking and eating quality.The results identifed seven lipid classes,55 lipid subclasses,and 1,086 lipid molecular species.Compared with the CI regime,the AWMD regime mainly altered lipid subclasses consisting of triglyceride(TG),ceramide(Cer),diglyceride(DG),bis-methyl lysophosphatidic acid(BisMePA),phosphocholine(PC),phosphoethanolamine(PE),monogalactosyldiacylglycerol(MGDG),and digalactosyl diglyceride(DGDG)in milled rice and improved cooking and eating quality of rice;in contrast,the AWSD regime distinctly changed lipid subclasses like TG,Cer,DG,PC,PE,hexosylceramide(Hex1Cer),DGDG,and BisMePA and degraded cooking and eating quality of rice.Specifcally,AWMD most signifcantly altered the expressions of lipid molecules,including DGDG(18:0_18:2),DGDG(16:0_14:0),PC(33:1),Cer(t17:0_26:0),and Cer(t17:0_16:0);AWSD most obviously influenced the expressions of TG(6:0_14:0_18:3),PC(41:1),TG(19:1_18:4_18:4),Hex1Cer(d18:2_24:0+O),and Hex1Cer(d18:2_24:1).These 10 altered lipid molecules in milled rice can be preferentially used for investigating their relationships with grain quality in rice.展开更多
Cinobufacini, a compound extracted from bufo toad, is a traditional Chinese medicine(TCM) that has been shown to have efficacy in cancer treatment.The cinobufacini injection is widely used in patients with moderate an...Cinobufacini, a compound extracted from bufo toad, is a traditional Chinese medicine(TCM) that has been shown to have efficacy in cancer treatment.The cinobufacini injection is widely used in patients with moderate and advanced liver cancer in China.In the present study, we aimed to determine the effects of cinobufacini injection for this specific category of patients.A search for randomized control trials(RCTs) using cinobufacini was conducted in the PubMed, EMBASE, CENTRAL, and the other four major Chinese databases.The systematic review was performed according to the recommendations of the Cochrane collaboration, and the RevMan 5.3.software was used for statistical analysis.A random-effects model was used to perform the data.Risk ratios(RR) with corresponding 95% confidence interval were calculated according to Cochrane handbook.A total of 11 RCTs consisting of 728 patients were included.All of the trials demonstrated significantly improved total response rates, total response rates of Karnofsky Performance Score(KPS), 1-to 2-year survival rates, and quality of life in the intervention groups injected with cinobufacini.There was no statistically significant difference between the groups(cinobufacini versus no cinobufacini; cinobufacini plus transcatheter arterial chemoembolization(TACE) versus TACE only) in terms of the 6-month survival rate, clinical benefit rate and clinical benefit rate of KPS.This systematic review demonstrated the beneficial effects of cinobufacini injection in terms of total response rate and the 1-to 2-year survival rate in patients with moderate and advanced liver cancer.The efficacy for the cinobufacini injection group might be better than that of the control group for treatment of moderate and advanced liver cancer.Given that the majority of the trials were of low quality, more high-quality prospective RCTs with strict design in accordance with CONSORT for TCM are needed.展开更多
基于Web of Science与中国知网数据库旱涝急转相关文献,利用CiteSpace软件对年度发文量、关键词共现与突现进行分析,系统综述了旱涝急转的识别方法、成因及影响的研究进展,并展望今后旱涝急转相关研究问题。结果表明:①旱涝急转的发文...基于Web of Science与中国知网数据库旱涝急转相关文献,利用CiteSpace软件对年度发文量、关键词共现与突现进行分析,系统综述了旱涝急转的识别方法、成因及影响的研究进展,并展望今后旱涝急转相关研究问题。结果表明:①旱涝急转的发文量逐年增加,国内发文量占总发文量的53.2%,研究历经初步探索(2005—2010年)、快速发展(2011—2018年)和稳定发展(2019—2024年)三阶段;外文研究在2018年后加速增长至2023年达峰值。②国内聚焦时空演变与大气环流机制,关键词以趋势分析,降水,低频振荡为主;国外侧重气候变化背景下旱涝急转的变化与影响,热点集中于Yangtze River,vegetation等。③旱涝急转目前缺乏统一、全面的识别方法;其成因分析多局限于气象因素,对其他成因的研究较为缺乏;其灾害影响研究主要集中于农业与植被,对社会经济、城市生态等领域的探讨较为薄弱。展开更多
To improve the electrorheological effect of electrorheological fluid (ERF), a new type of the electrosensitive particle material, polynaphthalene quinone was prepared, whose molecules contain blended atoms of nitrogen...To improve the electrorheological effect of electrorheological fluid (ERF), a new type of the electrosensitive particle material, polynaphthalene quinone was prepared, whose molecules contain blended atoms of nitrogen, oxygen, sulphur and big π bond conjugate system. In both DC and AC electric fields, the ERF material showed a distinct ER effect. Especially, in the alternating electric field, the shear stress of this material versus AC voltage has a better quadratic relation than that of the other materials. The experimental data showed that organic semiconductor polymers with big π bond conjugate system are a new type of electrosensitive particle materials which are worth well developing.展开更多
A Chebyshev fitting way for a propeller atlas across four quadrants is discussed. As an example, Chebyshev polynomial fitting results and its error analysis are given. Because it’s difficult generally to get a propel...A Chebyshev fitting way for a propeller atlas across four quadrants is discussed. As an example, Chebyshev polynomial fitting results and its error analysis are given. Because it’s difficult generally to get a propeller atlas across four quadrants, a way is used to construct an alternative with higher accuracy based on the properties. As an application example, an alternative for the propeller property of a Deep Submergence Vehicle across four quadrants is given practically and a simulation model of the four quadrants propeller for dynamic condition is set up. The model lays a foundation for DSV full operating-condition movement simulation. A lot of simulation work shows that the results are very close to the practical data and, therefore, are effective.展开更多
Gas chromatography-mass spectrometry(GC-MS) and the chemometric resolution method(alternative moving window factor analysis,AMWFA) were used for comparative analysis of volatile constituents in herbal pair(HP) flos lo...Gas chromatography-mass spectrometry(GC-MS) and the chemometric resolution method(alternative moving window factor analysis,AMWFA) were used for comparative analysis of volatile constituents in herbal pair(HP) flos lonicerae-caulis lonicerae(FL-CL) and its single herbs.The temperature-programmed retention index(PTRI) was also employed for the identification of compounds.In total,44,39,and 50 volatile chemical components in volatile oil of FL,CL and HP FL-CL were separately determined qualitatively and quantitatively,accounting for 87.22%,94.54% and 90.08% total contents of volatile oil of FL,CL and HP FL-CL,respectively.The results show that there are 32 common volatile constituents between HP FL-CL and single herb FL,33 common volatile constituents between HP FL-CL and single herb CL,and 10 new constituents in the volatile oil of HP FL-CL.展开更多
A dynamic transient flow analysis method considering complex factors such as the cyclic injection and production history in a gas field storage facility was established in view of the limitations of the existing metho...A dynamic transient flow analysis method considering complex factors such as the cyclic injection and production history in a gas field storage facility was established in view of the limitations of the existing methods for transient flow analysis and the characteristics of the injection-production operation of strongly heterogeneous gas reservoirs, and the corresponding theoretical charts were drawn. In addition, an injection-production dynamic transient flow analysis model named "three points and two stages" suitable for an underground gas storage(UGS) well with alternate working conditions was proposed. The "three points" refer to three time points during cyclic injection and production, namely, the starting point of gas injection for UGS construction, the beginning and ending points of the injection-production analysis stage;and the "two stages" refer to historical flow stage and injection-production analysis stage. The study shows that the dimensionless pseudo-pressure and dimensionless pseudo-pressure integral curves of UGS well flex downward in the early stage of the injection and production process, and the dimensionless pseudo-pressure integral derivative curve is convex during the gas production period and concave during the gas injection period, and the curves under different flow histories have atypical features. The new method present in this paper can analyze transient flow of UGS accurately. The application of this method to typical wells in Hutubi gas storage shows that the new method can fit the pressure history accurately, and obtain reliable parameters and results.展开更多
By means of the Second Law of Thermodynamics,thispaper gives out the entropy analysis method for vapor-comperession refrigeration system.The thermal irrevers-ibility of the system charged with R12 and its hopeful al-t...By means of the Second Law of Thermodynamics,thispaper gives out the entropy analysis method for vapor-comperession refrigeration system.The thermal irrevers-ibility of the system charged with R12 and its hopeful al-ternative refrlgerant R134a have been studied respective-ly.On the basis of all the research results of this paper,the measure used to save energy for vapor-compressionrefrigeration system has been put out.展开更多
文摘Alternating pulses current - chronopotentiometric stripping analysis (APC-CPSA) is a new method as a variant of chronopotentiometric stripping analysis (CPSA). During the stripping step an alternating pulse current with a high frequency in a square wave mode is imposed on the electrode system. Thus, tau and sensitivity of APC-CPSA is increased a lot. The tau, E similar to t equation and its reciprocal derivative equation for APC-CPSA are derived and verified by the experimental results.
文摘This paper studies the problem of tensor principal component analysis (PCA). Usually the tensor PCA is viewed as a low-rank matrix completion problem via matrix factorization technique, and nuclear norm is used as a convex approximation of the rank operator under mild condition. However, most nuclear norm minimization approaches are based on SVD operations. Given a matrix , the time complexity of SVD operation is O(mn2), which brings prohibitive computational complexity in large-scale problems. In this paper, an efficient and scalable algorithm for tensor principal component analysis is proposed which is called Linearized Alternating Direction Method with Vectorized technique for Tensor Principal Component Analysis (LADMVTPCA). Different from traditional matrix factorization methods, LADMVTPCA utilizes the vectorized technique to formulate the tensor as an outer product of vectors, which greatly improves the computational efficacy compared to matrix factorization method. In the experiment part, synthetic tensor data with different orders are used to empirically evaluate the proposed algorithm LADMVTPCA. Results have shown that LADMVTPCA outperforms matrix factorization based method.
基金supported by the Northeast Asia Biodiversity Research Center(grant number 411147021003).
文摘The predominant causal agent of poplar leaf blight is the pathogenic fungus Alternaria alternata (Fr.) Keissl., which exhibits host specificity toward Populus species. To elucidate the molecular response mechanisms of A. alternata under fludioxonil fungicide stress, the fungus was cultured at the half-maximal effective concentration (EC₅₀) of fludioxonil. Transcriptomic and metabolomic profiles were analyzed using mycelia harvested under these conditions. Comparative analysis revealed 1,001 differentially expressed genes (DEGs) in the resistant strain (RS) relative to the wild-type strain (WT), comprising 628 upregulated and 373 downregulated genes. Concurrently, 524 differentially accumulated metabolites (DAMs) were identified, with 336 upregulated and 188 downregulated metabolites. KEGG pathway enrichment demonstrated pronounced upregulation in glycerophospholipid metabolism, α-linolenic acid metabolism, nucleic acid biosynthesis, and glycosylation processes. Conversely, arachidonic acid and galactose metabolism pathways were suppressed. Significant downregulation was observed in phosphatidylinositol signaling, aflatoxin biosynthesis, and cutin/suberin/wax biosynthesis pathways. Transcriptomic profiling further indicated that upregulated DEGs were predominantly associated with amino sugar/nucleotide sugar metabolism, ABC transporters, aflatoxin biosynthesis, and purine metabolism, while downregulated DEGs were enriched in N-glycan biosynthesis, endoplasmic reticulum protein processing, steroid biosynthesis, and riboflavin metabolism. Fludioxonil exerted substantial inhibitory effects on fungal growth, pathogenicity, and metabolic activity. Mechanistically, A. alternata counteracted fungicide-induced stress through modulation of its antioxidant defense system. This integrative multi-omics study delineates the dynamic gene expression and metabolic reprogramming in A. alternata under fludioxonil exposure, providing novel insights into potential molecular targets and informing the development of next-generation fungicidal strategies for phytopathogen control.
基金supported by the Natural Science Foundation of Jiangsu Province,China(BK20241931 and BK20221371)the National Natural Science Foundation of China(32071943 and 32372214)the National Key Research and Development Program of China(2022YFD2300304)。
文摘Alternate wetting and soil drying irrigation(AWD)technique is crucial in infuencing grain quality in rice(Oryza sativa L.).Lipids are the third most abundant constituents in rice grains,after starch and proteins,and are closely related to grain quality.However,it remains unclear about the changes in lipids profling under different AWD regimes.This study set up three irrigation regimes including conventional irrigation(CI),alternate wetting and moderate soil drying irrigation(AWMD),and alternate wetting and severe soil drying irrigation(AWSD).It explored lipidome changes in milled rice of Yangdao 6(YD6)using the untargeted lipidomics approach and analyzed rice cooking and eating quality.The results identifed seven lipid classes,55 lipid subclasses,and 1,086 lipid molecular species.Compared with the CI regime,the AWMD regime mainly altered lipid subclasses consisting of triglyceride(TG),ceramide(Cer),diglyceride(DG),bis-methyl lysophosphatidic acid(BisMePA),phosphocholine(PC),phosphoethanolamine(PE),monogalactosyldiacylglycerol(MGDG),and digalactosyl diglyceride(DGDG)in milled rice and improved cooking and eating quality of rice;in contrast,the AWSD regime distinctly changed lipid subclasses like TG,Cer,DG,PC,PE,hexosylceramide(Hex1Cer),DGDG,and BisMePA and degraded cooking and eating quality of rice.Specifcally,AWMD most signifcantly altered the expressions of lipid molecules,including DGDG(18:0_18:2),DGDG(16:0_14:0),PC(33:1),Cer(t17:0_26:0),and Cer(t17:0_16:0);AWSD most obviously influenced the expressions of TG(6:0_14:0_18:3),PC(41:1),TG(19:1_18:4_18:4),Hex1Cer(d18:2_24:0+O),and Hex1Cer(d18:2_24:1).These 10 altered lipid molecules in milled rice can be preferentially used for investigating their relationships with grain quality in rice.
基金Science and Technology Project of Putian University,China(Grant No.2013035)
文摘Cinobufacini, a compound extracted from bufo toad, is a traditional Chinese medicine(TCM) that has been shown to have efficacy in cancer treatment.The cinobufacini injection is widely used in patients with moderate and advanced liver cancer in China.In the present study, we aimed to determine the effects of cinobufacini injection for this specific category of patients.A search for randomized control trials(RCTs) using cinobufacini was conducted in the PubMed, EMBASE, CENTRAL, and the other four major Chinese databases.The systematic review was performed according to the recommendations of the Cochrane collaboration, and the RevMan 5.3.software was used for statistical analysis.A random-effects model was used to perform the data.Risk ratios(RR) with corresponding 95% confidence interval were calculated according to Cochrane handbook.A total of 11 RCTs consisting of 728 patients were included.All of the trials demonstrated significantly improved total response rates, total response rates of Karnofsky Performance Score(KPS), 1-to 2-year survival rates, and quality of life in the intervention groups injected with cinobufacini.There was no statistically significant difference between the groups(cinobufacini versus no cinobufacini; cinobufacini plus transcatheter arterial chemoembolization(TACE) versus TACE only) in terms of the 6-month survival rate, clinical benefit rate and clinical benefit rate of KPS.This systematic review demonstrated the beneficial effects of cinobufacini injection in terms of total response rate and the 1-to 2-year survival rate in patients with moderate and advanced liver cancer.The efficacy for the cinobufacini injection group might be better than that of the control group for treatment of moderate and advanced liver cancer.Given that the majority of the trials were of low quality, more high-quality prospective RCTs with strict design in accordance with CONSORT for TCM are needed.
文摘基于Web of Science与中国知网数据库旱涝急转相关文献,利用CiteSpace软件对年度发文量、关键词共现与突现进行分析,系统综述了旱涝急转的识别方法、成因及影响的研究进展,并展望今后旱涝急转相关研究问题。结果表明:①旱涝急转的发文量逐年增加,国内发文量占总发文量的53.2%,研究历经初步探索(2005—2010年)、快速发展(2011—2018年)和稳定发展(2019—2024年)三阶段;外文研究在2018年后加速增长至2023年达峰值。②国内聚焦时空演变与大气环流机制,关键词以趋势分析,降水,低频振荡为主;国外侧重气候变化背景下旱涝急转的变化与影响,热点集中于Yangtze River,vegetation等。③旱涝急转目前缺乏统一、全面的识别方法;其成因分析多局限于气象因素,对其他成因的研究较为缺乏;其灾害影响研究主要集中于农业与植被,对社会经济、城市生态等领域的探讨较为薄弱。
文摘To improve the electrorheological effect of electrorheological fluid (ERF), a new type of the electrosensitive particle material, polynaphthalene quinone was prepared, whose molecules contain blended atoms of nitrogen, oxygen, sulphur and big π bond conjugate system. In both DC and AC electric fields, the ERF material showed a distinct ER effect. Especially, in the alternating electric field, the shear stress of this material versus AC voltage has a better quadratic relation than that of the other materials. The experimental data showed that organic semiconductor polymers with big π bond conjugate system are a new type of electrosensitive particle materials which are worth well developing.
文摘A Chebyshev fitting way for a propeller atlas across four quadrants is discussed. As an example, Chebyshev polynomial fitting results and its error analysis are given. Because it’s difficult generally to get a propeller atlas across four quadrants, a way is used to construct an alternative with higher accuracy based on the properties. As an application example, an alternative for the propeller property of a Deep Submergence Vehicle across four quadrants is given practically and a simulation model of the four quadrants propeller for dynamic condition is set up. The model lays a foundation for DSV full operating-condition movement simulation. A lot of simulation work shows that the results are very close to the practical data and, therefore, are effective.
基金Project(20976017) supported by the National Natural Science Foundation of China
文摘Gas chromatography-mass spectrometry(GC-MS) and the chemometric resolution method(alternative moving window factor analysis,AMWFA) were used for comparative analysis of volatile constituents in herbal pair(HP) flos lonicerae-caulis lonicerae(FL-CL) and its single herbs.The temperature-programmed retention index(PTRI) was also employed for the identification of compounds.In total,44,39,and 50 volatile chemical components in volatile oil of FL,CL and HP FL-CL were separately determined qualitatively and quantitatively,accounting for 87.22%,94.54% and 90.08% total contents of volatile oil of FL,CL and HP FL-CL,respectively.The results show that there are 32 common volatile constituents between HP FL-CL and single herb FL,33 common volatile constituents between HP FL-CL and single herb CL,and 10 new constituents in the volatile oil of HP FL-CL.
基金Supported by the CNPC Major Scientific and Technological Project(2019B-3204)PetroChina Major Scientific and Technological Project(kt2020-16-01)。
文摘A dynamic transient flow analysis method considering complex factors such as the cyclic injection and production history in a gas field storage facility was established in view of the limitations of the existing methods for transient flow analysis and the characteristics of the injection-production operation of strongly heterogeneous gas reservoirs, and the corresponding theoretical charts were drawn. In addition, an injection-production dynamic transient flow analysis model named "three points and two stages" suitable for an underground gas storage(UGS) well with alternate working conditions was proposed. The "three points" refer to three time points during cyclic injection and production, namely, the starting point of gas injection for UGS construction, the beginning and ending points of the injection-production analysis stage;and the "two stages" refer to historical flow stage and injection-production analysis stage. The study shows that the dimensionless pseudo-pressure and dimensionless pseudo-pressure integral curves of UGS well flex downward in the early stage of the injection and production process, and the dimensionless pseudo-pressure integral derivative curve is convex during the gas production period and concave during the gas injection period, and the curves under different flow histories have atypical features. The new method present in this paper can analyze transient flow of UGS accurately. The application of this method to typical wells in Hutubi gas storage shows that the new method can fit the pressure history accurately, and obtain reliable parameters and results.
文摘By means of the Second Law of Thermodynamics,thispaper gives out the entropy analysis method for vapor-comperession refrigeration system.The thermal irrevers-ibility of the system charged with R12 and its hopeful al-ternative refrlgerant R134a have been studied respective-ly.On the basis of all the research results of this paper,the measure used to save energy for vapor-compressionrefrigeration system has been put out.
