Objective:To observe the clinical efficacy of moxibustion with seed-sized moxa cone plus opioid drugs for moderate-to・severe cancer pain,and the effect on immune function in patients with cancer pain.Methods:A total o...Objective:To observe the clinical efficacy of moxibustion with seed-sized moxa cone plus opioid drugs for moderate-to・severe cancer pain,and the effect on immune function in patients with cancer pain.Methods:A total of 80 patients with moderate-to-severe cancer pain were randomized into an observation group and a control group by the random number table method,with 40 cases in each group.Both groups were treated with opioid drugs for an algesia accordi ng to the stan dardized man agement prin ciples for cancer pain.In addition,the observati on group was given moxibustion with seed-sized moxa cone.The treatment was performed once a day,continuous 5-day treatment with a 2-day interval constituted a treatment course,and a total of 2 courses were performed.The score of numerical rating scale(NRS)and 24 h eq ui vale nt morphi ne consumpti on was compared betwee n the two groups before treatment,after 1 treatment course and after 2 courses of treatment.The immune functions were compared between the two groups before and after 2 courses of treatment.Results:During the treatment,there were 3 dropouts in the control group,and 2 dropouts in the observation group.Before the treatme nt,there were no sign ificant differe nces in the NRS score and 24 h equivale nt morphine consumpti on betwee n the two groups(both P>0.05).The NRS scores of both two groups were quite stable during the whole treatment period,and there was no significant differenee in the intra-group comparison after treatment(both P>0.05),and there was no significant difference between the two groups at the same time point(both P>0.05).In the control group,the 24 h equivale nt morphine con sumpti on showed an in creasi ng trend.The dosage after 1 treatme nt course and 2 courses of treatment was statistically different from that before treatment in the control group(both P<0.01).There was no significant cha nge in the mea n 24 h equivale nt morphi ne con sumpti on in the observati on group compared with that before treatme nt(both P>0.05).After 2 courses of treatme nt,the 24 h equivale nt morphine con sumpti on in the observati on group was significantly lower than that in the control group at the same time point(P<0.05).Before treatment,there was no significant difference in the levels of T lymphocyte subsets(CD3:CD4+and CD4+/CD8+)between the two groups(all P>0.05).After treatment the levels of T lymphocyte subsets(CD3+Z CD4+and CD4+/CD8+)in the control group were lower than those before treatment(all P<0.05),while the levels in the observation group were higher than those before treatment,and the levels of CD3+and CD4+were significantly different from those before treatment(both P<0.05).After treatment,the levels of T lymphocyte subsets(CD3+,CD4+and CD4+/CD8+)of the observation group were significantly higher than those of the control group at the same time point(all P<0.05).Conclusion:Moxibustion with seed-sized moxa cone can reduce the dosage of opioid drugs used in patients with moderate-to-severe cancer pain and improve their immune functions.展开更多
Objective：To observe the clinical effect of wheat grain-sized cone moxibustion combined with fire needle therapy in the treatment of dorsal wrist ganglion （DWG）. Methods：A total of 63 patients with DWG were random...Objective：To observe the clinical effect of wheat grain-sized cone moxibustion combined with fire needle therapy in the treatment of dorsal wrist ganglion （DWG）. Methods：A total of 63 patients with DWG were randomized into a treatment group （n=32） and a control group （n=31）. Cases in the control group were treated with fire needle therapy. Based on the therapy given to the control group, cases in the treatment group were additionally given wheat grain-sized cone moxibustion therapy. Then the therapeutic efficacies and recurrence rate were evaluated. Results：After treatment, the overall effective rate was 93.8% in the treatment group, versus 77.4% in the control group, and the between-group comparison showed a statistical significance （P〈0.05）; 6 months after the treatment, the recurrence rate in the treatment group was obviously lower than that in the control group （P〈0.05）. Conclusion：The long-term and short-term effects of wheat grain-sized cone moxibustion combined with fire needle therapy in the treatment of DWG are better than those of fire needle therapy alone, and therefore, worth popularizing.展开更多
文摘Objective:To observe the clinical efficacy of moxibustion with seed-sized moxa cone plus opioid drugs for moderate-to・severe cancer pain,and the effect on immune function in patients with cancer pain.Methods:A total of 80 patients with moderate-to-severe cancer pain were randomized into an observation group and a control group by the random number table method,with 40 cases in each group.Both groups were treated with opioid drugs for an algesia accordi ng to the stan dardized man agement prin ciples for cancer pain.In addition,the observati on group was given moxibustion with seed-sized moxa cone.The treatment was performed once a day,continuous 5-day treatment with a 2-day interval constituted a treatment course,and a total of 2 courses were performed.The score of numerical rating scale(NRS)and 24 h eq ui vale nt morphi ne consumpti on was compared betwee n the two groups before treatment,after 1 treatment course and after 2 courses of treatment.The immune functions were compared between the two groups before and after 2 courses of treatment.Results:During the treatment,there were 3 dropouts in the control group,and 2 dropouts in the observation group.Before the treatme nt,there were no sign ificant differe nces in the NRS score and 24 h equivale nt morphine consumpti on betwee n the two groups(both P>0.05).The NRS scores of both two groups were quite stable during the whole treatment period,and there was no significant differenee in the intra-group comparison after treatment(both P>0.05),and there was no significant difference between the two groups at the same time point(both P>0.05).In the control group,the 24 h equivale nt morphine con sumpti on showed an in creasi ng trend.The dosage after 1 treatme nt course and 2 courses of treatment was statistically different from that before treatment in the control group(both P<0.01).There was no significant cha nge in the mea n 24 h equivale nt morphi ne con sumpti on in the observati on group compared with that before treatme nt(both P>0.05).After 2 courses of treatme nt,the 24 h equivale nt morphine con sumpti on in the observati on group was significantly lower than that in the control group at the same time point(P<0.05).Before treatment,there was no significant difference in the levels of T lymphocyte subsets(CD3:CD4+and CD4+/CD8+)between the two groups(all P>0.05).After treatment the levels of T lymphocyte subsets(CD3+Z CD4+and CD4+/CD8+)in the control group were lower than those before treatment(all P<0.05),while the levels in the observation group were higher than those before treatment,and the levels of CD3+and CD4+were significantly different from those before treatment(both P<0.05).After treatment,the levels of T lymphocyte subsets(CD3+,CD4+and CD4+/CD8+)of the observation group were significantly higher than those of the control group at the same time point(all P<0.05).Conclusion:Moxibustion with seed-sized moxa cone can reduce the dosage of opioid drugs used in patients with moderate-to-severe cancer pain and improve their immune functions.
基金supported by National Basic Research Program of China No.2015CB554502Acupuncture,Moxibustion&Tuina Provincial Key Discipline of Hunan University of Chinese Medicine2011 Collaborative Innovation Center of Hunan University of Chinese Medicine~~
文摘Objective：To observe the clinical effect of wheat grain-sized cone moxibustion combined with fire needle therapy in the treatment of dorsal wrist ganglion （DWG）. Methods：A total of 63 patients with DWG were randomized into a treatment group （n=32） and a control group （n=31）. Cases in the control group were treated with fire needle therapy. Based on the therapy given to the control group, cases in the treatment group were additionally given wheat grain-sized cone moxibustion therapy. Then the therapeutic efficacies and recurrence rate were evaluated. Results：After treatment, the overall effective rate was 93.8% in the treatment group, versus 77.4% in the control group, and the between-group comparison showed a statistical significance （P〈0.05）; 6 months after the treatment, the recurrence rate in the treatment group was obviously lower than that in the control group （P〈0.05）. Conclusion：The long-term and short-term effects of wheat grain-sized cone moxibustion combined with fire needle therapy in the treatment of DWG are better than those of fire needle therapy alone, and therefore, worth popularizing.
