We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and...We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.展开更多
Objectives To evaluate peripheral auditory dysfunction in senile dementia of Alzheimer’s disease (AD) and its relationship with cognitive dysfunction. Methods Pure tone thresholds,word recognition scores (WRS), acous...Objectives To evaluate peripheral auditory dysfunction in senile dementia of Alzheimer’s disease (AD) and its relationship with cognitive dysfunction. Methods Pure tone thresholds,word recognition scores (WRS), acoustic immittance and auditory brain-stem responses (ABR) were tested to evaluate the auditory function in 43 AD patients and 50 normal subjects. The test reliability in these subjects was examined before the test results were evaluated for their correlation with the Mini Mental State Examination(MMSE) score. Results There were no statistically significant differences in peripheral auditory functions between the two ears in the tested subjects or between the two groups when the auditometric results of the right ear were compared(P > 0.05). Also, there were no statistically significant differences between the two groups when audiometric test reliability, acoustic impedance and ABR results were compared(P > 0.05). Conclutions The pure tone audiometric threshold and WRS in AD patients are similar to those in comparable non-AD senile subjects. Peripheral auditory dysfunction is not related to cognitive dysfunction.展开更多
Introduction:With the widespread adoption of smartphones,Mobile Phone Dependence Syndrome(MPDS)has emerged as a significant public health concern.However,the relationship between family upbringing environment and MPDS...Introduction:With the widespread adoption of smartphones,Mobile Phone Dependence Syndrome(MPDS)has emerged as a significant public health concern.However,the relationship between family upbringing environment and MPDS among middle school students remains unclear.Methods:The study employed a multi-stage cluster random sampling method to conduct questionnaire and scale assessments among 1,928 students from eight middle schools in Guangzhou during April and May 2023.Propensity score matching was performed to control for confounding variables,including sex,grade,boarding status,and place of residence.used Multivariate logistic regression models were used to examine the associations between parental educational attainment,parenting styles,care levels,family economic conditions,and middle school students’MPDS.Results:After adjusting for covariates,this study revealed that middle school students whose fathers had educational attainment levels of junior high school[odds ratio(OR)=0.39,95%confidence interval(95%CI):0.17–0.90],senior high school,junior college,technical secondary school,or vocational university(OR=0.28,95%CI:0.12–0.67),or a bachelor’s degree and above(OR=0.34,95%CI:0.12–0.92)demonstrated significantly lower odds of MPDS compared to those whose fathers had only an elementary school education or below.Additionally,students whose fathers employed an authoritarian parenting style(OR=1.98,95%CI:1.22–3.21)showed significantly higher odds of MPDS compared to those whose fathers embraced a democratic parenting approach.Conclusion:Promoting democratic parenting styles among fathers and enhancing fathers’educational levels may be beneficial in reducing adolescents’MPDS risk.This study provides valuable insights for developing scientifically informed strategies aimed at promoting adolescents’physical and mental well-being.展开更多
文摘We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.
基金Beijing Brain Aging Key Laboratory Foundation (951890600)
文摘Objectives To evaluate peripheral auditory dysfunction in senile dementia of Alzheimer’s disease (AD) and its relationship with cognitive dysfunction. Methods Pure tone thresholds,word recognition scores (WRS), acoustic immittance and auditory brain-stem responses (ABR) were tested to evaluate the auditory function in 43 AD patients and 50 normal subjects. The test reliability in these subjects was examined before the test results were evaluated for their correlation with the Mini Mental State Examination(MMSE) score. Results There were no statistically significant differences in peripheral auditory functions between the two ears in the tested subjects or between the two groups when the auditometric results of the right ear were compared(P > 0.05). Also, there were no statistically significant differences between the two groups when audiometric test reliability, acoustic impedance and ABR results were compared(P > 0.05). Conclutions The pure tone audiometric threshold and WRS in AD patients are similar to those in comparable non-AD senile subjects. Peripheral auditory dysfunction is not related to cognitive dysfunction.
基金Supported by the Medical Science and Technology Research Foundation of Guangdong(Grant No.B2022109).
文摘Introduction:With the widespread adoption of smartphones,Mobile Phone Dependence Syndrome(MPDS)has emerged as a significant public health concern.However,the relationship between family upbringing environment and MPDS among middle school students remains unclear.Methods:The study employed a multi-stage cluster random sampling method to conduct questionnaire and scale assessments among 1,928 students from eight middle schools in Guangzhou during April and May 2023.Propensity score matching was performed to control for confounding variables,including sex,grade,boarding status,and place of residence.used Multivariate logistic regression models were used to examine the associations between parental educational attainment,parenting styles,care levels,family economic conditions,and middle school students’MPDS.Results:After adjusting for covariates,this study revealed that middle school students whose fathers had educational attainment levels of junior high school[odds ratio(OR)=0.39,95%confidence interval(95%CI):0.17–0.90],senior high school,junior college,technical secondary school,or vocational university(OR=0.28,95%CI:0.12–0.67),or a bachelor’s degree and above(OR=0.34,95%CI:0.12–0.92)demonstrated significantly lower odds of MPDS compared to those whose fathers had only an elementary school education or below.Additionally,students whose fathers employed an authoritarian parenting style(OR=1.98,95%CI:1.22–3.21)showed significantly higher odds of MPDS compared to those whose fathers embraced a democratic parenting approach.Conclusion:Promoting democratic parenting styles among fathers and enhancing fathers’educational levels may be beneficial in reducing adolescents’MPDS risk.This study provides valuable insights for developing scientifically informed strategies aimed at promoting adolescents’physical and mental well-being.