RNA molecules are widely regarded as one of the most ancient molecular forms of life.In 1960s,Francis Crick,Leslie Orgel and Carl R.Woese proposed that RNAs might be the original biomolecule,a concept that later cryst...RNA molecules are widely regarded as one of the most ancient molecular forms of life.In 1960s,Francis Crick,Leslie Orgel and Carl R.Woese proposed that RNAs might be the original biomolecule,a concept that later crystallized into the“Primordial RNA World”theory.The discovery of catalytic RNAs,called ribozymes,in the 1980s provided compelling experimental support for this idea.Over billions of years of evolution,from simple to complex organisms,RNAs have maintained their central roles in both the expression and the regulation of genetic information.展开更多
文摘RNA molecules are widely regarded as one of the most ancient molecular forms of life.In 1960s,Francis Crick,Leslie Orgel and Carl R.Woese proposed that RNAs might be the original biomolecule,a concept that later crystallized into the“Primordial RNA World”theory.The discovery of catalytic RNAs,called ribozymes,in the 1980s provided compelling experimental support for this idea.Over billions of years of evolution,from simple to complex organisms,RNAs have maintained their central roles in both the expression and the regulation of genetic information.