通过记录物理地址扩展(Physical Address Extensions,PAE)T6T/T6R与三汇内话SVCS3000之间的IP语音(Voice over IP,VoIP)连接的互联互通性,测试在正常、网络中断、实时传输协议(Real-time Transport Protocol,RTP)打包时长不匹配、修改...通过记录物理地址扩展(Physical Address Extensions,PAE)T6T/T6R与三汇内话SVCS3000之间的IP语音(Voice over IP,VoIP)连接的互联互通性,测试在正常、网络中断、实时传输协议(Real-time Transport Protocol,RTP)打包时长不匹配、修改主备模式以及远程电台控制等情况下SVCS3000与PAE的VoIP互联互通性,解决VoIP运营商之间通信存在的协议转移问题。展开更多
Superior vena cava syndrome(SVCS) caused by lung cancer accounts for 75% of patients with SVCS,which is one of the common complications of tumors.Interventional therapy is currently the most effective approach to reli...Superior vena cava syndrome(SVCS) caused by lung cancer accounts for 75% of patients with SVCS,which is one of the common complications of tumors.Interventional therapy is currently the most effective approach to relieve obstruction,but existing stents cannot inhibit or eliminate tumors,requiring postoperative radiotherapy and chemotherapy that may lead to secondary obstruction.Based on the characteristics of the tumor microenvironment and the interlayer ion replaceable properties of the layered material-montmorillonite(MMT),the composite coating(MMT/Em/PDA) of emodin(Em)-loaded MMT and dopamine was constructed on the magnesium alloy by liquid phase ion exchange technology and hydrothermal technology.The in vitro and in vivo results showed that the modified samples showed excellent corrosion resistance,the drug loading through adsorption and complexation with Zn^(2+)between MMT layers,and the drug-loaded samples possessed good pH and near-infrared response-controlled release drug performances.The MMT/Em/PDA sample exhibited an excellent photo thermal conversion performance.Photo thermal(PTT) synergistic drug therapy of samples could significantly promote the production of ROS in lung cancer cells damage mitochondria,and further inhibit cell adhesion,proliferation,and invasion by down-regulating PI3K-AKT and EMT signaling pathways,thereby causing tumor cell death.Furthermore,the multimodal therapies of samples promoted the repolarization of tumor-associated macrophages into the M1 phenotype to re-activate tumor immunity through activating the AKT-NF-κB signaling pathway.In normal tissues,they can significantly promote the M2 phenotype polarization to promote vascular tissue repair by inhibiting the AKT-NF-κB signaling pathway.This work helps to provide a new insight into designing the modified magnesium alloy.展开更多
为提升含高比例电力电子设备的电力系统暂态稳定性,提出一种基于广域测量系统(wide area measurement system,WAMS)的静止无功补偿器(static var compensator,SVC)优化控制策略。通过同步相量测量单元实时获取发电机母线电压相量,构建...为提升含高比例电力电子设备的电力系统暂态稳定性,提出一种基于广域测量系统(wide area measurement system,WAMS)的静止无功补偿器(static var compensator,SVC)优化控制策略。通过同步相量测量单元实时获取发电机母线电压相量,构建以发电机电功率与机械功率偏差最小为目标函数的粒子群优化模型,并结合电压幅值与相角灵敏度系数动态计算SVC最优无功功率注入量。创新性引入灵敏度系数刻画发电机有功功率对SVC无功功率的依赖关系,实现多发电机转子角振荡协同阻尼。在DIgSILENT PowerFactory平台搭建IEEE 14节点系统,仿真结果表明,所提策略可有效降低转子角振荡幅度及斜率,使临界清除时间延长40 ms。与传统本地控制方法相比,所提方法突破了单一振荡阻尼限制,利用WAMS信息实现多机协调控制,为提升复杂电力系统暂态稳定性提供了新思路。展开更多
文摘通过记录物理地址扩展(Physical Address Extensions,PAE)T6T/T6R与三汇内话SVCS3000之间的IP语音(Voice over IP,VoIP)连接的互联互通性,测试在正常、网络中断、实时传输协议(Real-time Transport Protocol,RTP)打包时长不匹配、修改主备模式以及远程电台控制等情况下SVCS3000与PAE的VoIP互联互通性,解决VoIP运营商之间通信存在的协议转移问题。
基金financially supported by the National Natural Science Foundation of China(Nos.52101292 and 52101291)Joint Founds of R&D Program of Henan Province(No.242301420026)+2 种基金China Postdoctoral Science Foundation(No.2021M702930)Henan Province Science and Technology Research Program Project(No.252102230112)Henan Province Medical Science and Technology Research Program Project(No.LHGJ20240963)
文摘Superior vena cava syndrome(SVCS) caused by lung cancer accounts for 75% of patients with SVCS,which is one of the common complications of tumors.Interventional therapy is currently the most effective approach to relieve obstruction,but existing stents cannot inhibit or eliminate tumors,requiring postoperative radiotherapy and chemotherapy that may lead to secondary obstruction.Based on the characteristics of the tumor microenvironment and the interlayer ion replaceable properties of the layered material-montmorillonite(MMT),the composite coating(MMT/Em/PDA) of emodin(Em)-loaded MMT and dopamine was constructed on the magnesium alloy by liquid phase ion exchange technology and hydrothermal technology.The in vitro and in vivo results showed that the modified samples showed excellent corrosion resistance,the drug loading through adsorption and complexation with Zn^(2+)between MMT layers,and the drug-loaded samples possessed good pH and near-infrared response-controlled release drug performances.The MMT/Em/PDA sample exhibited an excellent photo thermal conversion performance.Photo thermal(PTT) synergistic drug therapy of samples could significantly promote the production of ROS in lung cancer cells damage mitochondria,and further inhibit cell adhesion,proliferation,and invasion by down-regulating PI3K-AKT and EMT signaling pathways,thereby causing tumor cell death.Furthermore,the multimodal therapies of samples promoted the repolarization of tumor-associated macrophages into the M1 phenotype to re-activate tumor immunity through activating the AKT-NF-κB signaling pathway.In normal tissues,they can significantly promote the M2 phenotype polarization to promote vascular tissue repair by inhibiting the AKT-NF-κB signaling pathway.This work helps to provide a new insight into designing the modified magnesium alloy.
文摘为提升含高比例电力电子设备的电力系统暂态稳定性,提出一种基于广域测量系统(wide area measurement system,WAMS)的静止无功补偿器(static var compensator,SVC)优化控制策略。通过同步相量测量单元实时获取发电机母线电压相量,构建以发电机电功率与机械功率偏差最小为目标函数的粒子群优化模型,并结合电压幅值与相角灵敏度系数动态计算SVC最优无功功率注入量。创新性引入灵敏度系数刻画发电机有功功率对SVC无功功率的依赖关系,实现多发电机转子角振荡协同阻尼。在DIgSILENT PowerFactory平台搭建IEEE 14节点系统,仿真结果表明,所提策略可有效降低转子角振荡幅度及斜率,使临界清除时间延长40 ms。与传统本地控制方法相比,所提方法突破了单一振荡阻尼限制,利用WAMS信息实现多机协调控制,为提升复杂电力系统暂态稳定性提供了新思路。
