Although the Suidae animals were one of the most prosperous mammals, their taxa and phylogeny were poorly studied. To bridge this research gap, the complete mitochondrial DNA cyt b sequences （1140 bp）of one red rive...Although the Suidae animals were one of the most prosperous mammals, their taxa and phylogeny were poorly studied. To bridge this research gap, the complete mitochondrial DNA cyt b sequences （1140 bp）of one red river pig （ Potamochoerus porcus ）, one bearded pig （ Sus barbatus ）, and several Eurasian wild boars （ Sus scorfa ） were determined with direct PCR sequencing method. Incorporated with the sequences of other Suidae species obtained from GenBank, the phylogentic trees of Suidae species were constructed by Neighbor-Joining and Most Parsimony method. Our resuits showed that the babirousa was sister group of all other species. The African species clustered into a single clade, while the Eurasian species formed the other clade. The phylogenetic positions of the Sus species were consistent with their geographical distribution. Based on our phylogeographical results, the Sus species could be classified into three groups： （1） the relatively primitive animals from Philippine Islands （such as S. cebifrons and S. philippensis ）, Sulawesi and it＇s adjacent islands （S. celebensis）, （2） the Eurasian wild boars （S. scrofa and the mysterious S. salvanius）, and （3） other pigs （such as S. barbatus and S. verrucosus）, which might further diverged as the islands type （such as S. barbatus from Sumatra and Borneo） and the continental type （such as Malay Peninsula wild boar）.展开更多
Introduction:Suidae-associated zoonotic viruses represent a significant global public health threat through cross-species transmission events.Current research remains limited to localized outbreak investigations and l...Introduction:Suidae-associated zoonotic viruses represent a significant global public health threat through cross-species transmission events.Current research remains limited to localized outbreak investigations and lacks comprehensive,systematic global analysis.Methods:We collected human-Suidae virus data from the National Center for Biotechnology Information(NCBI)Virus Database,integrating viral characteristics,host information,and environmental and anthropogenic factors.Boosted Regression Trees(BRT)models were employed to evaluate cross-species transmission risk and identify key predictive factors.Results:A total of 43 human-Suidae zoonotic viruses reported durng 1882-2022 were evaluated.The Boosted Regression Trees(BRT)model achieved area under the curve(AUC)values of 0.924(training)and 0.804(testing).Host-human phylogenetic distance and viral genome size emerged as the primary predictors.Porcine circovirus 3(PCV3)demonstrated the highest predicted risk(>0.9).Conclusions:This study establishes a data-driven framework for assessing cross-species transmission risk,supporting early warning systems and targeted prevention strategies.The findings underscore the critical importance of One Health approaches and recommend enhanced surveillance and biosecurity measures for high-risk viruses such as PCV3.展开更多
The skull and mandible of a Late Miocene fossil pig,Chleuastochoerus,are compared morphologically with those of extant pigs and peccaries,and subjected to a functional analysis.The presence of a rostral bone in the sk...The skull and mandible of a Late Miocene fossil pig,Chleuastochoerus,are compared morphologically with those of extant pigs and peccaries,and subjected to a functional analysis.The presence of a rostral bone in the skull and relatively strong rostral muscles indicates that Chleuastochoerus possessed considerable digging ability,though the relatively narrow occipital surface and the shortness of the skull would have restricted the range of motion through which the skull could be swung.The distinctive pre-zygomatic plate and over-canine arch-niche may have played a role in protecting the skull and canines during digging.The massive masticatory muscles,reconstructed based on well-developed parietal and zygomatic crests,would have enabled the mouth to close quickly and contributed to moving the mandible both longitudinally and laterally.The configuration of the cranio-mandibular joint and its relatively high position show clearly that Chleuastochoerus was capable of both crushing and grinding movements during mastication.The comparatively simple structure of the crown surfaces of the cheek teeth suggests that the food of Chleuastochoerus may have been softer than that of extant suids.The diet of Chleuastochoerus is postulated to fall between those of true forest pigs and open habitat pigs,and the habitat of Chleuastochoerus to be relatively humid forest edge or nearby areas of open steppe.展开更多
文摘Although the Suidae animals were one of the most prosperous mammals, their taxa and phylogeny were poorly studied. To bridge this research gap, the complete mitochondrial DNA cyt b sequences （1140 bp）of one red river pig （ Potamochoerus porcus ）, one bearded pig （ Sus barbatus ）, and several Eurasian wild boars （ Sus scorfa ） were determined with direct PCR sequencing method. Incorporated with the sequences of other Suidae species obtained from GenBank, the phylogentic trees of Suidae species were constructed by Neighbor-Joining and Most Parsimony method. Our resuits showed that the babirousa was sister group of all other species. The African species clustered into a single clade, while the Eurasian species formed the other clade. The phylogenetic positions of the Sus species were consistent with their geographical distribution. Based on our phylogeographical results, the Sus species could be classified into three groups： （1） the relatively primitive animals from Philippine Islands （such as S. cebifrons and S. philippensis ）, Sulawesi and it＇s adjacent islands （S. celebensis）, （2） the Eurasian wild boars （S. scrofa and the mysterious S. salvanius）, and （3） other pigs （such as S. barbatus and S. verrucosus）, which might further diverged as the islands type （such as S. barbatus from Sumatra and Borneo） and the continental type （such as Malay Peninsula wild boar）.
文摘Introduction:Suidae-associated zoonotic viruses represent a significant global public health threat through cross-species transmission events.Current research remains limited to localized outbreak investigations and lacks comprehensive,systematic global analysis.Methods:We collected human-Suidae virus data from the National Center for Biotechnology Information(NCBI)Virus Database,integrating viral characteristics,host information,and environmental and anthropogenic factors.Boosted Regression Trees(BRT)models were employed to evaluate cross-species transmission risk and identify key predictive factors.Results:A total of 43 human-Suidae zoonotic viruses reported durng 1882-2022 were evaluated.The Boosted Regression Trees(BRT)model achieved area under the curve(AUC)values of 0.924(training)and 0.804(testing).Host-human phylogenetic distance and viral genome size emerged as the primary predictors.Porcine circovirus 3(PCV3)demonstrated the highest predicted risk(>0.9).Conclusions:This study establishes a data-driven framework for assessing cross-species transmission risk,supporting early warning systems and targeted prevention strategies.The findings underscore the critical importance of One Health approaches and recommend enhanced surveillance and biosecurity measures for high-risk viruses such as PCV3.
基金supported by National Natural Science Foundation of China (Grant Nos. 41202002, 40730210)Chinese Academy of Sciences (Grant No. XDB03020104)+1 种基金Ministry of Science and Technology of China (Grant No. 2012CB821906)Key Deployment Project of Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences
文摘The skull and mandible of a Late Miocene fossil pig,Chleuastochoerus,are compared morphologically with those of extant pigs and peccaries,and subjected to a functional analysis.The presence of a rostral bone in the skull and relatively strong rostral muscles indicates that Chleuastochoerus possessed considerable digging ability,though the relatively narrow occipital surface and the shortness of the skull would have restricted the range of motion through which the skull could be swung.The distinctive pre-zygomatic plate and over-canine arch-niche may have played a role in protecting the skull and canines during digging.The massive masticatory muscles,reconstructed based on well-developed parietal and zygomatic crests,would have enabled the mouth to close quickly and contributed to moving the mandible both longitudinally and laterally.The configuration of the cranio-mandibular joint and its relatively high position show clearly that Chleuastochoerus was capable of both crushing and grinding movements during mastication.The comparatively simple structure of the crown surfaces of the cheek teeth suggests that the food of Chleuastochoerus may have been softer than that of extant suids.The diet of Chleuastochoerus is postulated to fall between those of true forest pigs and open habitat pigs,and the habitat of Chleuastochoerus to be relatively humid forest edge or nearby areas of open steppe.
