Peanuts are widely produced and commonly eaten in China.They grow well in warm climates with moderate rainfall and sandy soil,and they have a relatively long growing season.In China,the main peanut-producing areas are...Peanuts are widely produced and commonly eaten in China.They grow well in warm climates with moderate rainfall and sandy soil,and they have a relatively long growing season.In China,the main peanut-producing areas are Henan,Shandong,and Hebei provinces.From planting to harvest,peanuts go through five main stages.展开更多
Salt stress is a critical factor affecting the growth and yield of rice.Egypt,the largest rice producer in North Africa and the Middle East,is facing contrasting challenges related to salinity in its agroecosystems.In...Salt stress is a critical factor affecting the growth and yield of rice.Egypt,the largest rice producer in North Africa and the Middle East,is facing contrasting challenges related to salinity in its agroecosystems.In this study,we compared the salt-induced responses among three rice varieties:Giza 176(Egyptian variety),Kaituodao(Chinese variety),and Pokkali(Sri Lanka variety,used as control)under normal and saline stress(100 mmol/L NaCl)conditions at two seedling stages through RNA-seq expression analysis.Giza 176 displayed a salt tolerance score of 7 on the SES(Standard Evaluation Score).Its transcriptome showed dynamic changes,with the number of upregulated genes increasing from 180 to 735,and downregulated genes increasing from 918 to 2930 from the one-week to two-week stress stages,with activated pathways in ion transport,reactive oxygen species(ROS)scavenging,and protein biosynthesis.展开更多
Pigs have emerged as valuable large-animal models for cardiac xenotransplantation;however,the temporal dynamics of myocardial development in this species remains insufficiently defined.This study analyzed gene express...Pigs have emerged as valuable large-animal models for cardiac xenotransplantation;however,the temporal dynamics of myocardial development in this species remains insufficiently defined.This study analyzed gene expression patterns across four key developmental stages(neonatal,juvenile,sexual maturity,and adulthood)to delineate the molecular mechanisms driving porcine myocardial development.Increases in heart weight were accompanied by proportional expansion of myocardial fiber area and chamber size,reflecting coordinated structural development.Transcriptomic profiling of myocardial tissue by RNA sequencing(RNA-seq)identified 2189 differentially expressed genes(DEGs)across stage comparisons.Short time-series expression miner(STEM)analysis classified these DEGs into four major expression clusters enriched in pathways associated with myocardial development,immune responses,cell proliferation,and metabolic processes.Among 359 DEGs conserved across all developmental stages,six candidate genes were strongly associated with myocardial development.Reverse transcription-quantitative real-time polymerase chain reaction(RT-qPCR)confirmed a significant correlation between the expression of these candidate genes and myocardial development in porcine tissue.These findings establish a transcriptomic framework for porcine myocardial maturation and provide a molecular basis for advancing cardiac xenotransplantation.展开更多
1.Objective The Eastern Junggar Kalamaili region in Xinjiang constitutes a significant tin metallogenic belt in northwest China(Fig.1a).It hosts four independent tin deposits-Kamusite,Ganliangzi,Beilekuduke,and Saresh...1.Objective The Eastern Junggar Kalamaili region in Xinjiang constitutes a significant tin metallogenic belt in northwest China(Fig.1a).It hosts four independent tin deposits-Kamusite,Ganliangzi,Beilekuduke,and Sareshenke-from west to east,supplemented by two tin mineralized points,namely Hongtujingzi and Sujiquan(Figs.1b).according to the ore type and the composition of gangue minerals,the tin deposits in the region are classified into two groups:Quartz vein type and greisen type,with the Sareshenke deposit ascribed to the former and the remainder to the latter.展开更多
Automated sleep stages classification facilitates clinical experts in conducting treatment for sleep disorders,as it is more time-efficient concerning the analysis of whole-night polysomnography(PSG).However,most of t...Automated sleep stages classification facilitates clinical experts in conducting treatment for sleep disorders,as it is more time-efficient concerning the analysis of whole-night polysomnography(PSG).However,most of the existing research only focused on public databases with channel systems incompatible with the current clinical measurements.To narrow the gap between theoretical models and real clinical practice,we propose a novel deep learning model,by combining the vision transformer with supervised contrastive learning,realizing the efficient sleep stages classification.Experimental results show that the model facilitates an easier classification of multi-channel PSG signals.The mean F1-scores of 79.2%and 76.5%on two public databases outperform the previous studies,showing the model’s great capability,and the performance of the proposed method on the children’s small database also presents a high mean accuracy of 88.6%.Our proposed model is validated not only on the public databases but the provided clinical database to strictly evaluate its clinical usage in practice.展开更多
[Objective]The aim was to study on the characteristics of soil organic carbon and nitrogen in rubber （Hevea brasiliensis Muell-Arg） plantations at different age stages in the western region of Hainan Island,so as to...[Objective]The aim was to study on the characteristics of soil organic carbon and nitrogen in rubber （Hevea brasiliensis Muell-Arg） plantations at different age stages in the western region of Hainan Island,so as to evaluate the ecological benefits of rubber plantations and provide basic data for studying the effect of tropical land utilization/cover change on the global carbon and nitrogen cycle. [Method]The situs was in Danzhou city,western region of Hainan Island,and the samples were four kinds of rubber plantations soil at different ages and one kind of control check （pepper,Piper nigrum L.） soil. In this research,four quadrats were set up in each sample,and the size of each was 20 cm×20 cm. Four specimens were gathered from four layers of 0-15,15-30,30-45,45-60,and the average of them was the last analysis result of each sample. Soil density was measured by cutting ring method,soil containing and hygroscopic water was detected by oven drying method,soil organic carbon （SOC） was measured by low temperature heated outside potassium dichromate oxidation-colorimetry method,and soil total nitrogen （STN） was detected by semimicro Kjeldahl method. [Result]SOC contents of different layers in rubber plantations soil at different age stages （including the CK pepper soil,the same as below） varied little,and the content of SOC in surface layer （0-15 cm） was higher,while the underlayer （45-60 cm） was lower than the average value; there was significant difference in SOC content among different kinds of soil,and the content was of 6.03-7.78 g/kg,tapping young trees （7 years） CK pepper mature age trees （30 years） prophase of young trees （2 years） tapping trees （16 years）; there was no significant difference in SOC storage among different kinds of soil,and the storage was of 61.33-74.29 t/hm2,mature age trees （30 years） tapping young trees （7 years） prophase of young trees （2 years） CK pepper tapping trees （16 years）; there was significant difference in STN content among rubber plantations soil at different age stages,the content was of 410.86-664.14 mg/kg2,CK pepper tapping young trees （7 years） prophase of young trees （2 years） mature age trees （30 years） tapping trees （16 years）,and STN content of tapping trees （16 years） soil was extremely lowest; there was significant difference in C/N ratio among different kinds of soil,the ratio was of 10.94-14.47,and the ratio of tapping trees （16 years） mature age trees （30 years） tapping young trees （7 years） CK pepper prophase of young trees （2 years）. [Conclusion]There wasn＇t unhealthy effect of rubber trees planted in tropical area on the content and storage of SOC,the content of STN and the ratio of C/N. there was no significant difference between rubber plantations and CK pepper soil,and the effects of rubber plantation on soil carbon-nitrogen was similar to that of other tropical crops （such as pepper）.展开更多
[Objective] The aim was to study the effects of short-term high temperature stress on the photosynthesis of potato in different growth stages. [Method] Choosing powder potato named Longshu No.3 widely cultivated in Ni...[Objective] The aim was to study the effects of short-term high temperature stress on the photosynthesis of potato in different growth stages. [Method] Choosing powder potato named Longshu No.3 widely cultivated in Ningxia as test material,the changes of stomata conductance （Gs）,transpiration rate （Tr） and CO2 concentration difference between internal and external leaf chamber,net photosynthetic rate （Pn） and photosynthetic water use efficiency （WUE） in different growth stages under short-term high temperature were analyzed. [Result] During seedling stage,the hysteretic nature of net photosynthetic rate and CO2 concentration difference between internal and external leaf chamber of potato could be found under high temperature stress,while the change trends of stomata conductance and transpiration rate under high temperature stress were consistent to that at normal temperature,but stomata conductance and transpiration rate were higher than those at normal temperature,and CO2 concentration difference between internal and external leaf chamber affected net photosynthetic rate most obviously. During branching stage,the change trends of net photosynthetic rate,CO2 concentration difference between internal and external leaf chamber,stomata conductance and transpiration rate under high temperature stress and normal temperature were similar,but they changed abruptly and reached peak value at noon under high temperature stress,while there existed consistent variation of water use efficiency under high temperature stress and at normal temperature,and CO2 concentration difference between internal and external leaf chamber also affected net photosynthetic rate most greatly,next came transpiration rate. [Conclusion] High temperature stress affected the photosynthesis of potato in different growth stages,and it was more obvious during branching stage than seedling stage,while CO2 concentration difference between internal and external leaf chamber had the most important influence on net photosynthetic rate.展开更多
[Objective] This study aimed to investigate the effects of waterlogging in different growth stages on nitrogen （N） uptake, distribution, and utilization of cotton. [Method] A pool-culture experiment in field was con...[Objective] This study aimed to investigate the effects of waterlogging in different growth stages on nitrogen （N） uptake, distribution, and utilization of cotton. [Method] A pool-culture experiment in field was conducted to investigate the effects of wateriogging through comparing WL1 （waterlogging at peak squaring stage） and WL2 （waterlogging at flowering and boll-forming stage） treatments with their controls respectively. [Result] The results showed that the effect of WL1 on N uptake of cotton root was stronger than WL2. At 20 days （d） after WL1 treatment, the root biomass （RB）, N uptake （NU）, and N uptake rate （NUR） significantly decreased by 38.1%, 48.6%, and 53.0% respectively. At 20 d after WL2 treatment, the RB, NU, and NUR significantly decreased by 27.3%, 46.0%, and 44.8% respectively. More N was distributed to root and leaf after WL1 treatment, and to square, flower, and boll after WL2 treatment. N physiological use efficiency increased by 11.4% and 44.4% after WL1 and WL2 treatments respectively. Further analysis showed that the effects of WL1 on yield and its components of cotton were stronger than WL2. The boll number, boll weight, and lint yield per plant significantly reduced by 40.5%, 12.4%, and 49.5% after WL1 treatment, and significantly decreased by 23.1%, 6.9%, and 29.9% after WL2 treatment, respectively. [Conclusion] The negative effects of water- logging at peak squaring stage on N nutrition and yield of cotton were stronger than waterlogging at flowering and boll-forming stage, indicating that more attention should be paid to waterlogging at peak squaring stage and sound N management can improve cotton regrowth and reduce yield loss after waterlogging.展开更多
Objective： To investigate the relationship among the latest WHO classification of thymoma, myasthenia gravis （MG） and clinical stages. Methods： To review the pathological sections of 74 patients with thymoma from ...Objective： To investigate the relationship among the latest WHO classification of thymoma, myasthenia gravis （MG） and clinical stages. Methods： To review the pathological sections of 74 patients with thymoma from 1980-2004 using WHO classification （1999）, the statistical software was used to analyze the relationship among the WHO classification, MG and clinical stages. Results： （1） Two cases of type A, 23 cases of type AB, 4 cases of type B1, 27 cases of type B2, 16 cases of type B3 and 2 cases of type C were classified. Type B2 more likely accompanied MG （P〈0.05）, while none with MG occurred for type C. （2） One patient was in stage Ⅰ, 30 were in stage Ⅱ, 38 were in stage Ⅲ, and 5 were in stage Ⅳ. The latest histologic classification was significantly correlated with Masaoka stages （P〈0.01）. Conclusion： The latest WHO classification was correlated with occurrence of MG and finely reflected clinical stage. It can also evaluate the prognosis of patients.展开更多
Group living is widespread across diverse taxa,and the mechanisms underlying collective decision-making in contexts of variable role division are critical for understanding the dynamics of group stability.While studie...Group living is widespread across diverse taxa,and the mechanisms underlying collective decision-making in contexts of variable role division are critical for understanding the dynamics of group stability.While studies on collective behavior in small animals such as fish and insects are well-established,similar research on large wild animals remains challenging due to the limited availability of sufficient and systematic field data.Here,we aimed to explore the collective decision-making pattern and its sexual difference for the dimorphic Tibetan antelopes Pantholops hodgsonii(chiru)in Xizang Autonomous Region,China,by analyzing individual leadership distribution,as well as the joining process,considering factors such as calving stages and joining ranks.The distinct correlations of decision participants’ratio with group size and decision duration underscore the trade-off between accuracy and speed in decision-making.Male antelopes display a more democratic decision-making pattern,while females exhibit more prompt responses after calving at an early stage.This study uncovers a partially shared decision-making strategy among Tibetan antelopes,suggesting flexible self-organization in group decision processes aligned with animal life cycle progression.展开更多
The rhizosphere bacteria play crucial roles in plant health and growth as they are involved in assimilating nutrients and resisting adverse conditions such as nutrient stress,drought,and wind erosion.Agriophyllum squa...The rhizosphere bacteria play crucial roles in plant health and growth as they are involved in assimilating nutrients and resisting adverse conditions such as nutrient stress,drought,and wind erosion.Agriophyllum squarrosum(L.)Moq.is a pioneer plant used in sand fixation due to its strong resistance to drought and wind erosion.However,the bacterial community characteristics and ecological function in the rhizosphere of A.squarrosum are poorly understood.In this study,soil samples were collected from different developmental stages(seedling stage,vegetative stage,reproductive stage,and withering stage)of A.squarrosum.Illumina Miseq sequencing was used to detect differences in soil bacterial abundance.The Phylogenetic Investigation of Communities by Reconstruction of Unobserved States(PICRUSt)program was used to predict bacterial functions,and the relationships among bacteria,functional populations,and soil nutrients were examined using a heatmap analysis.The results showed that the Shannon and Sobs indices of rhizosphere bacteria were significantly higher during the reproductive stage than during the other stages.Pantoea sp.(7.03%)was the dominant genus during the seedling stage;Arthrobacter sp.was the dominant genus during the vegetative(13.94%),reproductive(7.57%),and withering(12.30%)stages.The relative abundances of Chloroflexi,Acidobacteria,and Gemmatimonadetes were significantly high during the reproductive stage.According to the PICRUSt analysis,membrane transport,signal transduction,and environmental adaptation of the bacterial functional population occurred during the seedling stage.Carbohydrate metabolism increased during the vegetative stage,while energy metabolism,lipid metabolism,and biosynthesis of other secondary metabolites of the bacterial functional population significantly increased during the reproductive stage.The abundances of bacterial communities,functional genes,and soil nutrients were synergistically altered during various developmental stages.Our findings suggest that the developmental stages of A.squarrosum play a significant role in defining the composition and structure of bacterial communities in the rhizosphere.The results will provide a basis for better prediction and understanding of soil bacterial metabolic potential and functions of A.squarrosum rhizosphere in sandy areas.展开更多
Microplastics(MPs)have garnered significant international scrutiny as an emerging environmental pollutant,constituting one of the four principal global environmental threats and posing potential health hazards to huma...Microplastics(MPs)have garnered significant international scrutiny as an emerging environmental pollutant,constituting one of the four principal global environmental threats and posing potential health hazards to humans.However,data on the impact of MPs on the early life of the commercially important fish remain limited.In this study,polystyrene microspheres(PS-MPs)(1 and 5μm)were used to investigate the effects of MPs on the growth,development,and metabolism in early life stages of large yellow croaker Pseudosciaena crocea.Results indicate that MPs were enriched in the gastrointestinal tract and gills of the fish.In addition,PS-MPs(1μm)exhibited no obvious effects on embryo hatching and heart rates,while increased the mortality rate(23.00%vs.control 14.99%)and decreased the body length(4098.61±447.03μm vs.control with 2827.04±254.75μm)of the larvae at the highest exposure concentration(5×10^(4)items/L).Metabolomics analysis revealed that PS-MPs(5μm)induced mild perturbations in phospholipid metabolism,specifically alterations in phosphatidylethanolamine(PE)levels.These changes influenced the cell membranes of juvenile fish,and consequently elicited inflammatory responses,disrupted lipid homeostasis,and affected other critical physiological processes.Ultimately,these effects may avoid the growth retardation and potential mortality.Therefore,PS-MPs could affect negatively the fish health in the early life stage,which has implications for aquatic ecosystems.展开更多
The early life stages of marine organisms are pivotal in shaping community dynamics and resource availability.In this study,we focused on Portunus trituberculatus,a crustacean integral to China's fisheries economy...The early life stages of marine organisms are pivotal in shaping community dynamics and resource availability.In this study,we focused on Portunus trituberculatus,a crustacean integral to China's fisheries economy,and examined the effect of sea surface temperature(SST)in its critical early life stages on subsequent yields.To analyze the correlation between SST in different larval stages and the corresponding yield of P.trituberculatus,we simulated the transport and distribution of larvae from 2014 to 2022 by employing circulation models and Lagrangian particle tracking experiments(LPTE).In the five years(2014,2015,2016,2019,and 2020),particles were transported in a northwestern direction and moved in the direction of low SST.The distribution of particles in the megalopa stage(M stage)were located in the region of the lower temperature.In 2017,2018,and 2021,the particles were transported in a northeastern direction but they did not move with the gradient of low SST in these years,and the particles in the last M stage were located in the region where the SST was at the peak of the time period.In 2022,the distribution was observed for most of the particles in the southwestern part of Zhejiang coast,a small part of them were transported in the northwestern direction and a small amount of particles was distributed offshore along the northern area of the Zhejiang coast.The correlations between the SST at each stage of larvae with the corresponding year's yield showed that the yield of P.trituberculatus decreased significantly(R=-0.772,P=0.015)with increasing SST at the M stage.This study preliminarily explains the correlation between SST at the larval stage and the yield of P.trituberculatus and provides essential information for scientific stock enhancement in the future.展开更多
In order to improve the measurement precision and increase the reliability of the femtosecond laser transient thermoreflectance system, the relative optical path difference between pump and probe beams is prolonged, w...In order to improve the measurement precision and increase the reliability of the femtosecond laser transient thermoreflectance system, the relative optical path difference between pump and probe beams is prolonged, which can improve the fitting accuracy of the experimental data to the theoretical model. A modified experimental setup is devised with the pump path intercalated a moving stage identical to the one in the probe path, which extends the optical path difference of the probe beam relative to the pump beam from 4 to 8 ns. The measured results indicate that the uncertainty from the misalignment and divergence of both beams can be ignored when the last 4 ns experimental data are connected with those of the first 4 ns smoothly. The as-obtained thermal conductance of AI/Si and Cr/Si interfaces agrees well with the reported experimental values, which verifies the reliability of this modified version of this measurement.展开更多
Immature stages of 3 species of the tribe Ozophorini from China are described for the first time, they are Bryanellocoris orientalis Hidaka (3rd^5th instars), Primierus longispinus Zheng (4th^5th instars) and Vertoman...Immature stages of 3 species of the tribe Ozophorini from China are described for the first time, they are Bryanellocoris orientalis Hidaka (3rd^5th instars), Primierus longispinus Zheng (4th^5th instars) and Vertomannus brevicollum Zheng (4th^5th instars). Abrief study on fine structure of pale spots on head, pronotum and abdomen of 5th instar nymph of Bryanellocoris orientalis Hidaka was also given.展开更多
In this paper, the crawler, second instar female and male, prepupa, pupa and adult male of Cryptococcus ulmi are described and illustrated for the first time; adult female is redescribed; a key to all stages is gi...In this paper, the crawler, second instar female and male, prepupa, pupa and adult male of Cryptococcus ulmi are described and illustrated for the first time; adult female is redescribed; a key to all stages is given and the biology is briefly repor ted.展开更多
John Bunyan's The Pilgrim's Progress has been written to preach the Christian doctrines of salvation.Therefore its allegorical protagonists have gradually gone through four stages of development on the path to...John Bunyan's The Pilgrim's Progress has been written to preach the Christian doctrines of salvation.Therefore its allegorical protagonists have gradually gone through four stages of development on the path to salvation.This paper is focused on the earlier two stages,that is,the repentance of sins and the temptations after conversion.展开更多
The effect of nitrate （NO3^-） on rice （Oryza sativa L.） growth as well as N absorption and assimilation during different growth stages was examined using three typical rice cultivars. Dry weight, yield, N uptake, ...The effect of nitrate （NO3^-） on rice （Oryza sativa L.） growth as well as N absorption and assimilation during different growth stages was examined using three typical rice cultivars. Dry weight, yield, N uptake, nitrate reductase activity （NRA） in leaves, and glutamine synthetase activity （GSA） in roots and leaves during their entire growth periods, as well as the kinetic parameters of ammonium （NH4^＋） uptake at the seedling stage, were measured with solution culture experiments. Results indicated that addition of NH4^＋-N and NO3^-N at a ratio of 75：25 （NH4^＋＋NO3^- treatment） when compared with that of NH4^＋-N alone （NH4^＋ treatment） increased the dry weight of ‘Nanguang＇ cultivar by 30% and ‘Yunjing 38＇ cultivar by 31%, and also increased their grain yield by 21% and 17%, respectively. For the four growth stages, the total N accumulation in plants increased by an average of 36% for ‘Nanguang＇ and 31% for ‘Yunjing 38＇, whereas the increasing effect of NO3^- in the ‘4007＇ cultivar was only found at the seedling stage, in the NH4^＋＋NO3^- treatment compared to the NH4^＋ treatment, NRA in the leaves increased by 2.09 folds, and GSA increased by 92% in the roots and 52% in the leaves of the three cultivars. NO3^- supply increased the maximum uptake rate （Vmax） in the ‘Nanguang＇ and ‘Yunjing 38＇ cultivars, reflecting that the NO3^- itself, not the increasing N concentration, increased the uptake rate of NH4^＋ by rice. There was no effect on the apparent Michaelis-Menten constant （Kin） of the three cultivars. Thus, some replacement of NH4^＋ with NO3^-could greatly improve the growth of rice plants, mainly on account of the increased uptake of NH4^＋ promoted by NO3^-, and future studies should focus on the molecular mechanism of the increased uptake of NH4^＋ by NO3^-.展开更多
AIM： To characterize the peripheral T-cell subpopulation profiles and their correlation with hepatitis B virus （HBV） replication in different dinical stages of chronic HBV infection. METHODS： A total of 422 patien...AIM： To characterize the peripheral T-cell subpopulation profiles and their correlation with hepatitis B virus （HBV） replication in different dinical stages of chronic HBV infection. METHODS： A total of 422 patients with chronic HBV infection were enrolled in this study. The patients were divided into three stages： immune-tolerant stage, immune active stage, and immune-inactive carrier stage. Composition of peripheral T-cell subpopulations was determined by flow cytometry. HBV markers were detected by enzyme-linked immunosorbent assay. Serum HBV DNA load was assessed by quantitative real-time poiymerase chain reaction.RESULTS： CD8^＋ T-cells were significantly higher in patients at the immune-tolerant stage than in patients at the immune-active and -inactive carrier stages （36.87 ± 7.58 vs 34.37 ± 9.07, 36.87 ± 7.58 vs 28.09 ± 5.64, P 〈 0.001）. The peripheral blood in patients at the immune-tolerant and immune active stages contained more CD8^＋ T-cells than CD4^＋ T-cells （36.87 ± 7.58 vs 30.23 ± 6.35, 34.37 ± 9.07 vs 30.92 ± 7.40, P 〈 0.01）, whereas the peripheral blood in patients at the immune- inactive carrier stage and in normal controls contained less CD8^＋ T-cells than CD4^＋ T-cells （28.09 ± 5.64 vs 36.85 ±6.06, 24.02 ± 4.35 vs 38.94 ± 3.39, P 〈 0.01）. ANOVA linear trend test showed that CD8^＋ T-cells were significantly increased in patients with a high viral load （39.41 ± 7.36, 33.83 ± 7.50, 31.81 ± 5.95 and 26.89 ± 5.71, P 〈 0.001）, while CD4^＋ T-cells were significantly increased in patients with a low HBV DNA load （37.45 ± 6.24, 33.33 ± 5.61, 31.58 ± 6.99 and 27.56 ± 5.49, P 〈 0.001）. Nultiple regression analysis displayed that log copies of HBV DNA still maintained its highly significant coefficients for T-cell subpopulations, and was the strongest predictors for variations in CD3^＋, CD4^＋ and CD8^＋ cells and CD4^＋/CD8^＋ ratio after adjustment for age at HBV-infection, maternal HBV-infection status, presence of hepatitis B e antigen and HBV mutation.CONCLUSION： Differences in peripheral T-cell subpopulation profiles can be found in different clinical stages of chronic HBV infection. T-cell impairment is significantly associated with HBV load.展开更多
There are large-scale Mesozoic bimodal igneous rock associations on the continental margin of southeastern China. They aroused extensive attention in the 1980s because of their specific tectonic implications, and have...There are large-scale Mesozoic bimodal igneous rock associations on the continental margin of southeastern China. They aroused extensive attention in the 1980s because of their specific tectonic implications, and have been found frequently during recent geological surveys. This paper reviews the studies of regional Mesozoic bimodal rocks, and concludes that they can be subdivided into three stages, i.e., the Early Jurassic (209-170 Ma, the first (Ⅰ) stage), the Late Jurassic-early Early Cretaceous (154-121 Ma, the second (Ⅱ) stage), and the late Early Cretaceous-Late Cretaceous (115-85 Ma, the third (Ⅲ) stage). These three stages of bimodal rocks were formed in different tectonic settings, and are important indicators for regional Mesozoic tectonic evolution.展开更多
文摘Peanuts are widely produced and commonly eaten in China.They grow well in warm climates with moderate rainfall and sandy soil,and they have a relatively long growing season.In China,the main peanut-producing areas are Henan,Shandong,and Hebei provinces.From planting to harvest,peanuts go through five main stages.
基金funded by the National Key R&D Program of China(Grant No.2022YFE0139400)the Egyptian-Chinese Research Fund,and Science,Technology&Innovation Funding Authority Egypt(Grant No.46512)the National Natural Science Foundation of China(Grant No.261143470).
文摘Salt stress is a critical factor affecting the growth and yield of rice.Egypt,the largest rice producer in North Africa and the Middle East,is facing contrasting challenges related to salinity in its agroecosystems.In this study,we compared the salt-induced responses among three rice varieties:Giza 176(Egyptian variety),Kaituodao(Chinese variety),and Pokkali(Sri Lanka variety,used as control)under normal and saline stress(100 mmol/L NaCl)conditions at two seedling stages through RNA-seq expression analysis.Giza 176 displayed a salt tolerance score of 7 on the SES(Standard Evaluation Score).Its transcriptome showed dynamic changes,with the number of upregulated genes increasing from 180 to 735,and downregulated genes increasing from 918 to 2930 from the one-week to two-week stress stages,with activated pathways in ion transport,reactive oxygen species(ROS)scavenging,and protein biosynthesis.
基金supported by the National Natural Science Foundation of China(32222079 to L.J.and 32202621 to D.D.W.)。
文摘Pigs have emerged as valuable large-animal models for cardiac xenotransplantation;however,the temporal dynamics of myocardial development in this species remains insufficiently defined.This study analyzed gene expression patterns across four key developmental stages(neonatal,juvenile,sexual maturity,and adulthood)to delineate the molecular mechanisms driving porcine myocardial development.Increases in heart weight were accompanied by proportional expansion of myocardial fiber area and chamber size,reflecting coordinated structural development.Transcriptomic profiling of myocardial tissue by RNA sequencing(RNA-seq)identified 2189 differentially expressed genes(DEGs)across stage comparisons.Short time-series expression miner(STEM)analysis classified these DEGs into four major expression clusters enriched in pathways associated with myocardial development,immune responses,cell proliferation,and metabolic processes.Among 359 DEGs conserved across all developmental stages,six candidate genes were strongly associated with myocardial development.Reverse transcription-quantitative real-time polymerase chain reaction(RT-qPCR)confirmed a significant correlation between the expression of these candidate genes and myocardial development in porcine tissue.These findings establish a transcriptomic framework for porcine myocardial maturation and provide a molecular basis for advancing cardiac xenotransplantation.
基金supported by the National Key R&D Program of China(No.2021YFC2901802)project of the China Geological Survey(No.DD20240073)Key R&D Program of Shaanxi Province(No.2024GH-ZDXM-26).
文摘1.Objective The Eastern Junggar Kalamaili region in Xinjiang constitutes a significant tin metallogenic belt in northwest China(Fig.1a).It hosts four independent tin deposits-Kamusite,Ganliangzi,Beilekuduke,and Sareshenke-from west to east,supplemented by two tin mineralized points,namely Hongtujingzi and Sujiquan(Figs.1b).according to the ore type and the composition of gangue minerals,the tin deposits in the region are classified into two groups:Quartz vein type and greisen type,with the Sareshenke deposit ascribed to the former and the remainder to the latter.
基金the National Natural Science Foundation of China(No.52375254)the Interdisciplinary Program of Shanghai Jiao Tong University(No.21X010301670)the Open Project Program of SJTU-Pinghu Institute of Intelligent Optoelectronics(No.2022SPIOE104)。
文摘Automated sleep stages classification facilitates clinical experts in conducting treatment for sleep disorders,as it is more time-efficient concerning the analysis of whole-night polysomnography(PSG).However,most of the existing research only focused on public databases with channel systems incompatible with the current clinical measurements.To narrow the gap between theoretical models and real clinical practice,we propose a novel deep learning model,by combining the vision transformer with supervised contrastive learning,realizing the efficient sleep stages classification.Experimental results show that the model facilitates an easier classification of multi-channel PSG signals.The mean F1-scores of 79.2%and 76.5%on two public databases outperform the previous studies,showing the model’s great capability,and the performance of the proposed method on the children’s small database also presents a high mean accuracy of 88.6%.Our proposed model is validated not only on the public databases but the provided clinical database to strictly evaluate its clinical usage in practice.
基金Supported by the Project of the Basic Research Operation Cost of State Level Research Institutes "Long-term Location Investigation of Basic Data for Rubber Production " ( XJSYWFZX-2008-14 and XJSYWFZX-2007-2)the Project Natural Sciences Fund of Hainan Province (807045)~~
文摘[Objective]The aim was to study on the characteristics of soil organic carbon and nitrogen in rubber （Hevea brasiliensis Muell-Arg） plantations at different age stages in the western region of Hainan Island,so as to evaluate the ecological benefits of rubber plantations and provide basic data for studying the effect of tropical land utilization/cover change on the global carbon and nitrogen cycle. [Method]The situs was in Danzhou city,western region of Hainan Island,and the samples were four kinds of rubber plantations soil at different ages and one kind of control check （pepper,Piper nigrum L.） soil. In this research,four quadrats were set up in each sample,and the size of each was 20 cm×20 cm. Four specimens were gathered from four layers of 0-15,15-30,30-45,45-60,and the average of them was the last analysis result of each sample. Soil density was measured by cutting ring method,soil containing and hygroscopic water was detected by oven drying method,soil organic carbon （SOC） was measured by low temperature heated outside potassium dichromate oxidation-colorimetry method,and soil total nitrogen （STN） was detected by semimicro Kjeldahl method. [Result]SOC contents of different layers in rubber plantations soil at different age stages （including the CK pepper soil,the same as below） varied little,and the content of SOC in surface layer （0-15 cm） was higher,while the underlayer （45-60 cm） was lower than the average value; there was significant difference in SOC content among different kinds of soil,and the content was of 6.03-7.78 g/kg,tapping young trees （7 years） CK pepper mature age trees （30 years） prophase of young trees （2 years） tapping trees （16 years）; there was no significant difference in SOC storage among different kinds of soil,and the storage was of 61.33-74.29 t/hm2,mature age trees （30 years） tapping young trees （7 years） prophase of young trees （2 years） CK pepper tapping trees （16 years）; there was significant difference in STN content among rubber plantations soil at different age stages,the content was of 410.86-664.14 mg/kg2,CK pepper tapping young trees （7 years） prophase of young trees （2 years） mature age trees （30 years） tapping trees （16 years）,and STN content of tapping trees （16 years） soil was extremely lowest; there was significant difference in C/N ratio among different kinds of soil,the ratio was of 10.94-14.47,and the ratio of tapping trees （16 years） mature age trees （30 years） tapping young trees （7 years） CK pepper prophase of young trees （2 years）. [Conclusion]There wasn＇t unhealthy effect of rubber trees planted in tropical area on the content and storage of SOC,the content of STN and the ratio of C/N. there was no significant difference between rubber plantations and CK pepper soil,and the effects of rubber plantation on soil carbon-nitrogen was similar to that of other tropical crops （such as pepper）.
基金Supported by National Natural Science Foundation of China(40765003)National Key Technology R &D Program in the 11th Five Year Plan of China (2007BAC03A02)~~
文摘[Objective] The aim was to study the effects of short-term high temperature stress on the photosynthesis of potato in different growth stages. [Method] Choosing powder potato named Longshu No.3 widely cultivated in Ningxia as test material,the changes of stomata conductance （Gs）,transpiration rate （Tr） and CO2 concentration difference between internal and external leaf chamber,net photosynthetic rate （Pn） and photosynthetic water use efficiency （WUE） in different growth stages under short-term high temperature were analyzed. [Result] During seedling stage,the hysteretic nature of net photosynthetic rate and CO2 concentration difference between internal and external leaf chamber of potato could be found under high temperature stress,while the change trends of stomata conductance and transpiration rate under high temperature stress were consistent to that at normal temperature,but stomata conductance and transpiration rate were higher than those at normal temperature,and CO2 concentration difference between internal and external leaf chamber affected net photosynthetic rate most obviously. During branching stage,the change trends of net photosynthetic rate,CO2 concentration difference between internal and external leaf chamber,stomata conductance and transpiration rate under high temperature stress and normal temperature were similar,but they changed abruptly and reached peak value at noon under high temperature stress,while there existed consistent variation of water use efficiency under high temperature stress and at normal temperature,and CO2 concentration difference between internal and external leaf chamber also affected net photosynthetic rate most greatly,next came transpiration rate. [Conclusion] High temperature stress affected the photosynthesis of potato in different growth stages,and it was more obvious during branching stage than seedling stage,while CO2 concentration difference between internal and external leaf chamber had the most important influence on net photosynthetic rate.
基金Supported by Jiangsu Agricultural Science and Technology Independent-innovation Fund Project(SCX(13)5071)National Natural Science Foundation of China(30900877)~~
文摘[Objective] This study aimed to investigate the effects of waterlogging in different growth stages on nitrogen （N） uptake, distribution, and utilization of cotton. [Method] A pool-culture experiment in field was conducted to investigate the effects of wateriogging through comparing WL1 （waterlogging at peak squaring stage） and WL2 （waterlogging at flowering and boll-forming stage） treatments with their controls respectively. [Result] The results showed that the effect of WL1 on N uptake of cotton root was stronger than WL2. At 20 days （d） after WL1 treatment, the root biomass （RB）, N uptake （NU）, and N uptake rate （NUR） significantly decreased by 38.1%, 48.6%, and 53.0% respectively. At 20 d after WL2 treatment, the RB, NU, and NUR significantly decreased by 27.3%, 46.0%, and 44.8% respectively. More N was distributed to root and leaf after WL1 treatment, and to square, flower, and boll after WL2 treatment. N physiological use efficiency increased by 11.4% and 44.4% after WL1 and WL2 treatments respectively. Further analysis showed that the effects of WL1 on yield and its components of cotton were stronger than WL2. The boll number, boll weight, and lint yield per plant significantly reduced by 40.5%, 12.4%, and 49.5% after WL1 treatment, and significantly decreased by 23.1%, 6.9%, and 29.9% after WL2 treatment, respectively. [Conclusion] The negative effects of water- logging at peak squaring stage on N nutrition and yield of cotton were stronger than waterlogging at flowering and boll-forming stage, indicating that more attention should be paid to waterlogging at peak squaring stage and sound N management can improve cotton regrowth and reduce yield loss after waterlogging.
文摘Objective： To investigate the relationship among the latest WHO classification of thymoma, myasthenia gravis （MG） and clinical stages. Methods： To review the pathological sections of 74 patients with thymoma from 1980-2004 using WHO classification （1999）, the statistical software was used to analyze the relationship among the WHO classification, MG and clinical stages. Results： （1） Two cases of type A, 23 cases of type AB, 4 cases of type B1, 27 cases of type B2, 16 cases of type B3 and 2 cases of type C were classified. Type B2 more likely accompanied MG （P〈0.05）, while none with MG occurred for type C. （2） One patient was in stage Ⅰ, 30 were in stage Ⅱ, 38 were in stage Ⅲ, and 5 were in stage Ⅳ. The latest histologic classification was significantly correlated with Masaoka stages （P〈0.01）. Conclusion： The latest WHO classification was correlated with occurrence of MG and finely reflected clinical stage. It can also evaluate the prognosis of patients.
基金supported by the National Natural Science Foundation of China(Grant no.32101237)the China Postdoctoral Science Foundation(Grant no.2021M691522)+1 种基金the National Key Research and Development Program(Grant no.2022YFC3202104)the Tibet Major Science and Technology Project(Grant no.XZ201901-GA-06).
文摘Group living is widespread across diverse taxa,and the mechanisms underlying collective decision-making in contexts of variable role division are critical for understanding the dynamics of group stability.While studies on collective behavior in small animals such as fish and insects are well-established,similar research on large wild animals remains challenging due to the limited availability of sufficient and systematic field data.Here,we aimed to explore the collective decision-making pattern and its sexual difference for the dimorphic Tibetan antelopes Pantholops hodgsonii(chiru)in Xizang Autonomous Region,China,by analyzing individual leadership distribution,as well as the joining process,considering factors such as calving stages and joining ranks.The distinct correlations of decision participants’ratio with group size and decision duration underscore the trade-off between accuracy and speed in decision-making.Male antelopes display a more democratic decision-making pattern,while females exhibit more prompt responses after calving at an early stage.This study uncovers a partially shared decision-making strategy among Tibetan antelopes,suggesting flexible self-organization in group decision processes aligned with animal life cycle progression.
基金supported by the Natural Science Foundation Project of Inner Mongolia Autonomous Region(2024LHMS03017)Research Capacity Enhancement“Unveiling and Leading”Project of Inner Mongolia Forestry Science Research Institute(2024NLTS03).
文摘The rhizosphere bacteria play crucial roles in plant health and growth as they are involved in assimilating nutrients and resisting adverse conditions such as nutrient stress,drought,and wind erosion.Agriophyllum squarrosum(L.)Moq.is a pioneer plant used in sand fixation due to its strong resistance to drought and wind erosion.However,the bacterial community characteristics and ecological function in the rhizosphere of A.squarrosum are poorly understood.In this study,soil samples were collected from different developmental stages(seedling stage,vegetative stage,reproductive stage,and withering stage)of A.squarrosum.Illumina Miseq sequencing was used to detect differences in soil bacterial abundance.The Phylogenetic Investigation of Communities by Reconstruction of Unobserved States(PICRUSt)program was used to predict bacterial functions,and the relationships among bacteria,functional populations,and soil nutrients were examined using a heatmap analysis.The results showed that the Shannon and Sobs indices of rhizosphere bacteria were significantly higher during the reproductive stage than during the other stages.Pantoea sp.(7.03%)was the dominant genus during the seedling stage;Arthrobacter sp.was the dominant genus during the vegetative(13.94%),reproductive(7.57%),and withering(12.30%)stages.The relative abundances of Chloroflexi,Acidobacteria,and Gemmatimonadetes were significantly high during the reproductive stage.According to the PICRUSt analysis,membrane transport,signal transduction,and environmental adaptation of the bacterial functional population occurred during the seedling stage.Carbohydrate metabolism increased during the vegetative stage,while energy metabolism,lipid metabolism,and biosynthesis of other secondary metabolites of the bacterial functional population significantly increased during the reproductive stage.The abundances of bacterial communities,functional genes,and soil nutrients were synergistically altered during various developmental stages.Our findings suggest that the developmental stages of A.squarrosum play a significant role in defining the composition and structure of bacterial communities in the rhizosphere.The results will provide a basis for better prediction and understanding of soil bacterial metabolic potential and functions of A.squarrosum rhizosphere in sandy areas.
基金Supported by the Pioneer and Leading Goose R&D Program of Zhejiang(No.2023C03130)the National Key R&D Program of China(No.2019YFD0901101)+4 种基金the National Natural Science Foundation of China(No.42076169)the Oceanic Interdisciplinary Program of Shanghai Jiao Tong University(Nos.SL2022ZD203,SL2022MS012)the Zhejiang Provincial Natural Science Founds for Distinguished Young Scientists(No.LR21D060001)the State Key Laboratory of Satellite Ocean Environment Dynamics(No.SOEDZZ1902)the ChinaAPEC Cooperation Fund(No.2029901)。
文摘Microplastics(MPs)have garnered significant international scrutiny as an emerging environmental pollutant,constituting one of the four principal global environmental threats and posing potential health hazards to humans.However,data on the impact of MPs on the early life of the commercially important fish remain limited.In this study,polystyrene microspheres(PS-MPs)(1 and 5μm)were used to investigate the effects of MPs on the growth,development,and metabolism in early life stages of large yellow croaker Pseudosciaena crocea.Results indicate that MPs were enriched in the gastrointestinal tract and gills of the fish.In addition,PS-MPs(1μm)exhibited no obvious effects on embryo hatching and heart rates,while increased the mortality rate(23.00%vs.control 14.99%)and decreased the body length(4098.61±447.03μm vs.control with 2827.04±254.75μm)of the larvae at the highest exposure concentration(5×10^(4)items/L).Metabolomics analysis revealed that PS-MPs(5μm)induced mild perturbations in phospholipid metabolism,specifically alterations in phosphatidylethanolamine(PE)levels.These changes influenced the cell membranes of juvenile fish,and consequently elicited inflammatory responses,disrupted lipid homeostasis,and affected other critical physiological processes.Ultimately,these effects may avoid the growth retardation and potential mortality.Therefore,PS-MPs could affect negatively the fish health in the early life stage,which has implications for aquatic ecosystems.
基金Supported by the National Key Research and Development Program of China(No.2019YFD0901304)the Public Welfare Technology Application Research Project of Zhejiang(No.LGN21C190009)the Science and Technology Project of Zhoushan(No.2022C41003)。
文摘The early life stages of marine organisms are pivotal in shaping community dynamics and resource availability.In this study,we focused on Portunus trituberculatus,a crustacean integral to China's fisheries economy,and examined the effect of sea surface temperature(SST)in its critical early life stages on subsequent yields.To analyze the correlation between SST in different larval stages and the corresponding yield of P.trituberculatus,we simulated the transport and distribution of larvae from 2014 to 2022 by employing circulation models and Lagrangian particle tracking experiments(LPTE).In the five years(2014,2015,2016,2019,and 2020),particles were transported in a northwestern direction and moved in the direction of low SST.The distribution of particles in the megalopa stage(M stage)were located in the region of the lower temperature.In 2017,2018,and 2021,the particles were transported in a northeastern direction but they did not move with the gradient of low SST in these years,and the particles in the last M stage were located in the region where the SST was at the peak of the time period.In 2022,the distribution was observed for most of the particles in the southwestern part of Zhejiang coast,a small part of them were transported in the northwestern direction and a small amount of particles was distributed offshore along the northern area of the Zhejiang coast.The correlations between the SST at each stage of larvae with the corresponding year's yield showed that the yield of P.trituberculatus decreased significantly(R=-0.772,P=0.015)with increasing SST at the M stage.This study preliminarily explains the correlation between SST at the larval stage and the yield of P.trituberculatus and provides essential information for scientific stock enhancement in the future.
基金The National Basic Research Program of China(973 Program)(No.2011CB707605)the National Natural Science Foundation of China(No.51205061,50925519,51106029)+1 种基金the Natural Science Foundation of Jiangsu Province(No.BK2012340)the Ph.D.Programs Foundation of Ministry of Education of China(No.20110092120006)
文摘In order to improve the measurement precision and increase the reliability of the femtosecond laser transient thermoreflectance system, the relative optical path difference between pump and probe beams is prolonged, which can improve the fitting accuracy of the experimental data to the theoretical model. A modified experimental setup is devised with the pump path intercalated a moving stage identical to the one in the probe path, which extends the optical path difference of the probe beam relative to the pump beam from 4 to 8 ns. The measured results indicate that the uncertainty from the misalignment and divergence of both beams can be ignored when the last 4 ns experimental data are connected with those of the first 4 ns smoothly. The as-obtained thermal conductance of AI/Si and Cr/Si interfaces agrees well with the reported experimental values, which verifies the reliability of this modified version of this measurement.
基金The project was supported by "Education Grant" of National Natural SciencesFoundation of China (No. 108)
文摘Immature stages of 3 species of the tribe Ozophorini from China are described for the first time, they are Bryanellocoris orientalis Hidaka (3rd^5th instars), Primierus longispinus Zheng (4th^5th instars) and Vertomannus brevicollum Zheng (4th^5th instars). Abrief study on fine structure of pale spots on head, pronotum and abdomen of 5th instar nymph of Bryanellocoris orientalis Hidaka was also given.
文摘In this paper, the crawler, second instar female and male, prepupa, pupa and adult male of Cryptococcus ulmi are described and illustrated for the first time; adult female is redescribed; a key to all stages is given and the biology is briefly repor ted.
文摘John Bunyan's The Pilgrim's Progress has been written to preach the Christian doctrines of salvation.Therefore its allegorical protagonists have gradually gone through four stages of development on the path to salvation.This paper is focused on the earlier two stages,that is,the repentance of sins and the temptations after conversion.
基金Project supported by the National Natural Science Foundation of China (Nos. 30390082 and 40471074)
文摘The effect of nitrate （NO3^-） on rice （Oryza sativa L.） growth as well as N absorption and assimilation during different growth stages was examined using three typical rice cultivars. Dry weight, yield, N uptake, nitrate reductase activity （NRA） in leaves, and glutamine synthetase activity （GSA） in roots and leaves during their entire growth periods, as well as the kinetic parameters of ammonium （NH4^＋） uptake at the seedling stage, were measured with solution culture experiments. Results indicated that addition of NH4^＋-N and NO3^-N at a ratio of 75：25 （NH4^＋＋NO3^- treatment） when compared with that of NH4^＋-N alone （NH4^＋ treatment） increased the dry weight of ‘Nanguang＇ cultivar by 30% and ‘Yunjing 38＇ cultivar by 31%, and also increased their grain yield by 21% and 17%, respectively. For the four growth stages, the total N accumulation in plants increased by an average of 36% for ‘Nanguang＇ and 31% for ‘Yunjing 38＇, whereas the increasing effect of NO3^- in the ‘4007＇ cultivar was only found at the seedling stage, in the NH4^＋＋NO3^- treatment compared to the NH4^＋ treatment, NRA in the leaves increased by 2.09 folds, and GSA increased by 92% in the roots and 52% in the leaves of the three cultivars. NO3^- supply increased the maximum uptake rate （Vmax） in the ‘Nanguang＇ and ‘Yunjing 38＇ cultivars, reflecting that the NO3^- itself, not the increasing N concentration, increased the uptake rate of NH4^＋ by rice. There was no effect on the apparent Michaelis-Menten constant （Kin） of the three cultivars. Thus, some replacement of NH4^＋ with NO3^-could greatly improve the growth of rice plants, mainly on account of the increased uptake of NH4^＋ promoted by NO3^-, and future studies should focus on the molecular mechanism of the increased uptake of NH4^＋ by NO3^-.
文摘AIM： To characterize the peripheral T-cell subpopulation profiles and their correlation with hepatitis B virus （HBV） replication in different dinical stages of chronic HBV infection. METHODS： A total of 422 patients with chronic HBV infection were enrolled in this study. The patients were divided into three stages： immune-tolerant stage, immune active stage, and immune-inactive carrier stage. Composition of peripheral T-cell subpopulations was determined by flow cytometry. HBV markers were detected by enzyme-linked immunosorbent assay. Serum HBV DNA load was assessed by quantitative real-time poiymerase chain reaction.RESULTS： CD8^＋ T-cells were significantly higher in patients at the immune-tolerant stage than in patients at the immune-active and -inactive carrier stages （36.87 ± 7.58 vs 34.37 ± 9.07, 36.87 ± 7.58 vs 28.09 ± 5.64, P 〈 0.001）. The peripheral blood in patients at the immune-tolerant and immune active stages contained more CD8^＋ T-cells than CD4^＋ T-cells （36.87 ± 7.58 vs 30.23 ± 6.35, 34.37 ± 9.07 vs 30.92 ± 7.40, P 〈 0.01）, whereas the peripheral blood in patients at the immune- inactive carrier stage and in normal controls contained less CD8^＋ T-cells than CD4^＋ T-cells （28.09 ± 5.64 vs 36.85 ±6.06, 24.02 ± 4.35 vs 38.94 ± 3.39, P 〈 0.01）. ANOVA linear trend test showed that CD8^＋ T-cells were significantly increased in patients with a high viral load （39.41 ± 7.36, 33.83 ± 7.50, 31.81 ± 5.95 and 26.89 ± 5.71, P 〈 0.001）, while CD4^＋ T-cells were significantly increased in patients with a low HBV DNA load （37.45 ± 6.24, 33.33 ± 5.61, 31.58 ± 6.99 and 27.56 ± 5.49, P 〈 0.001）. Nultiple regression analysis displayed that log copies of HBV DNA still maintained its highly significant coefficients for T-cell subpopulations, and was the strongest predictors for variations in CD3^＋, CD4^＋ and CD8^＋ cells and CD4^＋/CD8^＋ ratio after adjustment for age at HBV-infection, maternal HBV-infection status, presence of hepatitis B e antigen and HBV mutation.CONCLUSION： Differences in peripheral T-cell subpopulation profiles can be found in different clinical stages of chronic HBV infection. T-cell impairment is significantly associated with HBV load.
基金the NationalNatural Science Foundation of China(Grant 40002005)the 1:250,000-scale Regional Survey Program-theShengxian sheet(No.20001300006141) the ChinaGeological Survey Comprehensive Research Program(No.200113000053).
文摘There are large-scale Mesozoic bimodal igneous rock associations on the continental margin of southeastern China. They aroused extensive attention in the 1980s because of their specific tectonic implications, and have been found frequently during recent geological surveys. This paper reviews the studies of regional Mesozoic bimodal rocks, and concludes that they can be subdivided into three stages, i.e., the Early Jurassic (209-170 Ma, the first (Ⅰ) stage), the Late Jurassic-early Early Cretaceous (154-121 Ma, the second (Ⅱ) stage), and the late Early Cretaceous-Late Cretaceous (115-85 Ma, the third (Ⅲ) stage). These three stages of bimodal rocks were formed in different tectonic settings, and are important indicators for regional Mesozoic tectonic evolution.
