A series of novel cyclic derivatives have been synthesized by utilizing a nickel powder mediated radical cyclization as the key step. The structures of the new compounds were confirmed by 1H-NMR and MS.
The first synthesis of squarnosamide,a new compound isolated from Annona squamosa, was achieved in seven steps.The over all yield was 14%.The compound was identified by^1 H,^(13)C NMR and MS.
基金This program was supported by National Key Basic Research Program(973)(No.G1998051125).
文摘A series of novel cyclic derivatives have been synthesized by utilizing a nickel powder mediated radical cyclization as the key step. The structures of the new compounds were confirmed by 1H-NMR and MS.
文摘The first synthesis of squarnosamide,a new compound isolated from Annona squamosa, was achieved in seven steps.The over all yield was 14%.The compound was identified by^1 H,^(13)C NMR and MS.
