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Teaching Analysis of CT and MR Imaging Technology
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作者 WANG Yuzhu 《外文科技期刊数据库(文摘版)教育科学》 2021年第2期201-203,共3页
With the development of medical and health care and the advancement of high-end technologies such as computers and artificial intelligence, great changes have taken place in medical imaging technology. On the one hand... With the development of medical and health care and the advancement of high-end technologies such as computers and artificial intelligence, great changes have taken place in medical imaging technology. On the one hand, medical imaging technology plays a more and more important role in clinical work and becomes an indispensable and important means in clinical practice. On the other hand, it also poses new challenges to the implementation of medical imaging technology. Although the development of undergraduate education has been promoted in China, the clinical experience, especially the experience in imaging technology, is relatively lacking, and the clinical teaching is relatively lack of a unified and specific plan. The purpose of this paper is to analyze the relevant teaching contents of CT and MRI in medical imaging technology, so as to provide necessary reference in the future practice and teaching process. 展开更多
关键词 medical imaging technology ct and MR TEACHING
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The Value Analysis of CT Imaging Technology in the Diagnosis of Femoral Head Necrosis
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作者 LI Yanming 《外文科技期刊数据库(文摘版)医药卫生》 2021年第11期711-714,共6页
Objective: to explore the accuracy and sensitivity of bone malformation in C T diagnosis group. Methods: from March 2019 to June 2020, 72 patients suspected of osteonecrosis were selected and treated in our hospital. ... Objective: to explore the accuracy and sensitivity of bone malformation in C T diagnosis group. Methods: from March 2019 to June 2020, 72 patients suspected of osteonecrosis were selected and treated in our hospital. All patients underwent C-T examination, X-ray examination and magnetic resonance diagnosis. Statistical analysis was made on the bone state of femoral head defect diagnosed by C-T scan, X-ray and magnetic resonance, as well as the accuracy of C-T scan, X-ray and magnetic resonance diagnosis, and the sensitivity and specificity of femoral defect. Results: according to the final clinical diagnosis, out of 72 patients suspected of osteonecrosis, a total of 1 patient was diagnosed as osteoporosis. A total of 65 patients with femoral diseases, the positive rate of femoral necrosis was higher than that of CT scan and X-ray, while the positive rate of femoral necrosis was higher than that of X-ray, with statistical significance (P < 0.05). The accuracy, sensitivity and specificity of magnetic resonance diagnosis of femoral defect were higher than those of t-scan and x-ray scan, and the accuracy and sensitivity of CT scan were higher than those of x-ray, the difference was statistically significant (P < 0.05). Compared with X-ray films (P > 0.05), the features found by computed tomography of femoral necrosis have no statistical significance Conclusion: magnetic resonance diagnosis has higher value in clinical diagnosis of patients with femoral head necrosis than CT scan and X-ray films. 展开更多
关键词 ct imaging technology diagnosis of femoral head necrotic value
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Value of ^(99m)Tc-MDP SPECT/CT fusion imaging and CT in evaluating the extent of mandibular invasion by malignant tumor of oral cavity 被引量:1
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作者 Qingyun Duan Muyun Jia +6 位作者 Rongtao Yuan Lingxue Bu Wei Shang Xiaoming Jin Ningyi Li Jie Zhao Guoming Wang 《The Chinese-German Journal of Clinical Oncology》 CAS 2012年第12期694-698,共5页
Objective: The aim of our study was to compare the value of computed tomography (CT) and 99mTc-methylene- diphosphonate (MDP) SPECT (single photon emission computed tomography)/CT fusion imaging in determining ... Objective: The aim of our study was to compare the value of computed tomography (CT) and 99mTc-methylene- diphosphonate (MDP) SPECT (single photon emission computed tomography)/CT fusion imaging in determining the extent of mandibular invasion by malignant tumor of the oral cavity. Methods: This study had local ethical committee approval, and all patients gave written informed consent. Fifty-three patients were revealed mandibular invasion by malignant tumor of the oral cavity underwent CT and SPECT/CT. The patients were divided into two groups: group A (invasion-periphery-type) and group B (invasion-center- type). Two radiologists assessed the CT images and two nuclear medicine physicians separately assessed the $PECT/CT images in consensus and without knowledge of the results of other imaging tests. The extent of bone involvement suggested with an imaging modality was compared with pathological findings in the surgical specimen. Results: With pathological findings as the standard of reference, Group A: The extent of mandibular invasion by malignant tumor under- went SPECT/CT was 1.02 _+ 0.20 cm larger than that underwent pathological findings. And the extent of mandibular invasion underwent CT was 1.42 + 0.35 cm smaller than that underwent pathological examination. There were significant difference among the three methods (P 〈 0.01). Group B: The extent of mandibular invasion by malignant tumor underwent SPECT/CT was 1.3 + 0.39 cm larger than that underwent pathological examination. The extent of mandibular invasion underwent CT was 2.55 + 1.44 cm smaller than that underwent pathological findings. There were significant difference among the three methods (P 〈 0.01). The extent of mandibular invasion underwent SPECT/CT was the extent which surgeon must excise to get clear margins. Conclusion: SPECT/CT fusion imaging has significant clinical value in determining the extent of mandibular inva- sion by malignant tumor of oral cavity. 展开更多
关键词 spect/ct fusion imaging mandibular invasion malignant tumor
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Application of Dual-Energy CT Non-Linear Fusion Technology in Improving CTA Image Quality of Renal Cancer 被引量:1
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作者 Shuiqing Zhuo Xiaoling Chen +2 位作者 Jingping Yu Sihui Zeng Lizhi Liu 《Open Journal of Medical Imaging》 2018年第3期73-80,共8页
Objective: To explore the significance of dual-energy CT non-linear fusion technique in improving the quality of CTA image of renal cancer. Methods: The CTA images of 100 patients who had been confirmed by pathology a... Objective: To explore the significance of dual-energy CT non-linear fusion technique in improving the quality of CTA image of renal cancer. Methods: The CTA images of 100 patients who had been confirmed by pathology as renal cancer were collected and were randomly divided into experimental group and control group with 50 cases respectively. The two groups of patients were treated with iodine concentration of 300 mg/ml and 350 mg/ml non-ionic contrast agent, with a dosage of 1.5 ml/kg and an injection rate of 4 ml/s. The contrast agent intelligently tracking method was adopted bolus. The control group used the conventional CTA scanning, with a reference tube voltage/tube current of 100 kv/ref150 mas. The experimental group adopted the double energy scanning, with ball tube A and ball tube B. The reference tube voltage/tube current was 100 kv/ref250 mas and sn150 kv/ref125 mas respectively. The images of the experimental group were non-linear fused to obtain the Mono+ 55 kev single-energy images. The CT value, SNR contrast ratio of the abdominal aorta, renal artery and tumor tissue of the experimental group images and the 100 KV images and the Mono+ 55 kev images of the control group were compared. The objective evaluation and subjective evaluation of the image quality of the three groups of images was performed. Results: The results showed that the 100 kV images of the experimental group were statistically different from those of the control group (P05) in CT value, SNR and CNR (P 0.05). And there was no statistically significant difference between the non-linear fusion single-energy Mono+ 55 kev images and the control group images in CT value, SNR and CNR (P > 0.05). The subjective evaluation of image quality showed that there was no significant difference between Mono+ 55 kev images and control group images, and the quality of Mono+ 55 kev images was higher than that of experimental group 100 kV images. Conclusion: The dual-energy CT non-linear fusion technique can improve the quality of CTA image in patients with renal cancer, and it is possible to obtain high quality CTA images with low iodine concentration contrast agent. 展开更多
关键词 Dual-Source ct NON-LINEAR FUSION technology RENAL Cancer COMPUTED Tomographic ANGIOGRAPHY image Quality
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Status and prospects of frozen soil studies using CT technology
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作者 ShiJie Chen ShuPing Zhao +2 位作者 Wei Ma QianTao Zhu LiLi Xing 《Research in Cold and Arid Regions》 CSCD 2014年第2期107-115,共9页
This paper introduces the characteristics of Computed Tomography (CT) technology and reviews its history, current situation, representative achievements, and use of using CT technology on frozen soil study, includin... This paper introduces the characteristics of Computed Tomography (CT) technology and reviews its history, current situation, representative achievements, and use of using CT technology on frozen soil study, including auxiliary equipment specially de- signed for frozen soil studies. CT numbers are used to analyze frozen soil internal structure change, defining and exploring dam- age evolution, and use of CT images on observing soil mesostructure. Finally, this paper presents existing problems confronted by using CT in frozen soil studies, possible solutions and challenges, among which, we introduce high quality CT image processing for frozen soils, and relations between CT number change and each component change on frozen soil samples within the region of interest. It is shown that present CT technology is one of the most ideal and effective technology to study frozen soil mesostructure using non-desmactive testing. CT technology will play a key role in the study and development in the field of frozen soil by means of auxiliary equipment and the digital imaging processing. 展开更多
关键词 ct technology frozen soil DAMAGE mesostructure change ct image processing
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A comparative study of SPECT/CT fusion imaging and CT in infiltrated mandible by gingival carcinoma
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作者 Hongwei Liu Guichang Li +2 位作者 Ningyi Li Jie Wang Baomei Fang 《The Chinese-German Journal of Clinical Oncology》 CAS 2009年第8期485-487,共3页
Objective: The aim of the study was to evaluate the clinical value of ^99mTc-methylene diphosphonic acid (MDP) SPECT/CT fusion imaging and CT scanning in diagnosis of infiltrated mandible by gingival carcinoma. Met... Objective: The aim of the study was to evaluate the clinical value of ^99mTc-methylene diphosphonic acid (MDP) SPECT/CT fusion imaging and CT scanning in diagnosis of infiltrated mandible by gingival carcinoma. Methods: 18 cases of gingival carcinoma were processed infiltrated mandible by ^99mTc-MDP SPECT/CT fusion image and CT, and their scanning results compared with pathology findings. Results: Eleven of 13 cases with well-differentiated squamous cell carcinoma showed positive images, one of 11 cases was false positive images by pathology findings, and 10 cases were exhibited infiltrated mandibles; 5 cases with moderately differentiated and poorly differentiated squamous call carcinoma showed positive images, pathology showed carcinoma call had infiltrated cavum ossis of mandible. Five of 18 cases were positive images by CT. Conclusion: ^99mTc-MDP SPECT/CT fusion imaging is a useful method in diagnosis of infiltrated mandible by gingival carcinoma. 展开更多
关键词 gingival carcinoma fusion imaging spect/ct ^99MTC-MDP ct
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Lymphoscintigraphy Using Dynamic Imaging and SPECT/CT in Chylothorax
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作者 Asami Ohtsuka Yusuke Inoue +2 位作者 Yuji Asano Reiko Woodhams Kazu Shiomi 《Open Journal of Medical Imaging》 2013年第3期86-89,共4页
Lymphoscintigraphy readily provides confirmation of chylothorax but not detailed localization of the leakage site. A 77-year-old woman developed traumatic chylothorax and underwent lymphoscintigraphy with radiolabeled... Lymphoscintigraphy readily provides confirmation of chylothorax but not detailed localization of the leakage site. A 77-year-old woman developed traumatic chylothorax and underwent lymphoscintigraphy with radiolabeled albumin to identify the site of lymph leakage. Dynamic imaging demonstrated appearance of focal activity presumably in the upper mediastinum, followed by spread to the left hemithorax. Subsequently, SPECT/CT showed that the leakage site was located in the left side of the upper mediastinum, and this location was confirmed during video-assisted thoracoscopic surgery. Dynamic imaging demonstrated the site of first appearance of abnormal activity, and SPECT/CT enabled detailed localization of the abnormal activity with anatomic correlation. The combination of dynamic imaging with SPECT/CT appears to be recommendable for lymphoscintigraphic assessment of chylothorax. 展开更多
关键词 CHYLOTHORAX LYMPHOSCINTIGRAPHY 99mTc-DTPA-HSA DYNAMIC imaging spect/ct
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Value of SPECT/CT Fusion Imaging in Differential Diagnosis of Benign and Malignant Spinal Lesions
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作者 CHEN Yi SHEN Chao HUANG Yue 《外文科技期刊数据库(文摘版)医药卫生》 2021年第1期139-140,共3页
Objective: to analyze the application value of SPECT/CT fusion imaging technology in differential diagnosis of benign and malignant spinal lesions. Methods: all the subjects were diagnosed with SPECT/CT fusion imaging... Objective: to analyze the application value of SPECT/CT fusion imaging technology in differential diagnosis of benign and malignant spinal lesions. Methods: all the subjects were diagnosed with SPECT/CT fusion imaging technology, and then all the subjects were diagnosed with CT-guided percutaneous spinal biopsy. 42 cases of benign lesions were confirmed and 18 cases of malignant lesions, accounting for 70.00% and 30.00% respectively. Taking CT-guided biopsy as the gold standard, the detection rates of benign and malignant spinal lesions by SPECT/CT fusion imaging were statistically compared. Results: there was no significant difference between differential diagnosis accuracy and gold standard in SPECT/CT fusion imaging technique (P > 0.05). Conclusion: it has high differential diagnosis accuracy, can effectively identify patients' diseases, and is worthy of clinical application. 展开更多
关键词 spinal lesions spect/ct fusion imaging technology differential diagnosis
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SPECT/CT融合显像在分化型甲状腺癌^(131)Ⅰ治疗中的应用价值 被引量:1
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作者 吴波 杜世强 赵铭 《新疆医科大学学报》 2025年第8期1116-1120,共5页
目的 探究SPECT/CT融合显像在分化型甲状腺癌患者接受放射性核素^(131)Ⅰ治疗中的应用价值。方法 选取2024年1月至2025年1月期间在本院行放射性核素^(131)Ⅰ治疗的120例分化型甲状腺癌(DTC)患者作为研究对象,所有患者均接受放射性核素^(... 目的 探究SPECT/CT融合显像在分化型甲状腺癌患者接受放射性核素^(131)Ⅰ治疗中的应用价值。方法 选取2024年1月至2025年1月期间在本院行放射性核素^(131)Ⅰ治疗的120例分化型甲状腺癌(DTC)患者作为研究对象,所有患者均接受放射性核素^(131)Ⅰ治疗。受试者根据影像学检查方式分为两组,对照组患者使用SPECT成像技术进行定位诊断,研究组患者使用SPECT/CT融合显像技术进行定位诊断。比较两组病灶定位准确率、残留率及转移率的差异,并采用χ^(2)检验、Logistic回归模型及ROC曲线评价SPECT与SPECT/CT的诊断效能。结果 SPECT组与SPECT/CT组之间原发病灶、TSH、Tg、^(131)Ⅰ剂量相比,差异有统计学意义(P<0.05),多因素Logistic回归分析结果显示,原发病灶、TSH、Tg、^(131)Ⅰ剂量均为分化型甲状腺癌的危险因素(P<0.05)。与SPECT组相比,SPECT/CT组病灶定位准确率更高,治疗后其病灶组织残留率和癌细胞远处转移率均更低,差异有统计学意义(P<0.05)。SPECT显像诊断灵敏度为97.62%,准确度为83.33%,特异度50.00%。SPECT/CT融合显像诊断灵敏度为96.15%,准确度为90.00%,特异度50.00%。SPECT/CT融合显像诊断效能优于SPECT显像诊断(P<0.05)。结论 SPECT/CT融合显像在DTC患者放射性核素^(131)Ⅰ治疗中具有显著的应用价值,可以为临床医生提供全面、准确的诊断依据,有助于提高治疗效果。 展开更多
关键词 spect/ct融合显像 分化型甲状腺癌 放射性核素^(131)Ⅰ
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SPECT/CT断层融合显像在恶性肿瘤骨转移鉴别诊断中的应用价值 被引量:1
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作者 王群 周静兰 +2 位作者 沈欣桐 李庆啸 沈智辉 《标记免疫分析与临床》 2025年第3期469-473,507,共6页
目的恶性肿瘤骨转移是肿瘤晚期常见的临床表现,准确的早期诊断对于患者预后至关重要。本文旨在探讨SPECT/CT断层融合显像在骨转移鉴别诊断中的独特优势和临床应用价值。方法采用回顾性对照研究方法,选取80例存在骨异常放射性浓聚灶的患... 目的恶性肿瘤骨转移是肿瘤晚期常见的临床表现,准确的早期诊断对于患者预后至关重要。本文旨在探讨SPECT/CT断层融合显像在骨转移鉴别诊断中的独特优势和临床应用价值。方法采用回顾性对照研究方法,选取80例存在骨异常放射性浓聚灶的患者作为研究对象,采用全身骨显像、SPECT断层显像及SPECT/CT断层融合显像3种不同的影像学方法进行对比分析。结果80例患者中,SPECT/CT断层融合显像在诊断准确性、灵敏度和特异性方面显著优于其他两种常规检查方法。具体而言,SPECT/CT断层融合显像的诊断准确率高达94.5%,灵敏度和特异性分别达到97.2%和92.3%,对于不同肿瘤类型的检出率存在显著差异,乳腺癌、肺癌和前列腺癌的检出率较高,分别为85.71%、84.21%和83.33%。相比之下,传统的全身骨显像虽然灵敏度较高,但特异性明显较差,诊断准确率仅为55.2%,特异性仅为23.5%。SPECT断层显像的诊断效能介于两者之间,但整体表现仍不及SPECT/CT断层融合显像。SPECT/CT断层融合显像的灵敏度、特异性、准确性及阳性预测率均高于SPECT断层显像及全身骨显像,差异均具有统计学意义(P<0.05)。结论SPECT/CT断层融合显像在恶性肿瘤骨转移鉴别诊断中具有显著优势,能够显著提高病灶检出率和诊断准确率。这一影像学技术为临床医生提供了更精确的诊断工具,有望进一步提升肿瘤骨转移的早期诊断水平。 展开更多
关键词 spect/ct断层融合显像 spect断层显像 全身骨显像 骨转移 诊断准确率
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SPECT/CT融合显像检查在原发性甲状旁腺功能亢进症(PHPT)术前诊断中的应用价值
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作者 张红 张剑斌 丁婷婷 《延边大学医学学报》 2025年第12期17-20,共4页
目的:评价在原发性甲状旁腺功能亢进症(PHPT)术前诊断中应用单光子发射计算机断层成像/电子计算机断层扫描(SPECT/CT)融合显像检查的价值。方法:研究对象为2020年1月—2024年12月因甲状旁腺激素(PTH)水平升高进入厦门大学附属中山医院接... 目的:评价在原发性甲状旁腺功能亢进症(PHPT)术前诊断中应用单光子发射计算机断层成像/电子计算机断层扫描(SPECT/CT)融合显像检查的价值。方法:研究对象为2020年1月—2024年12月因甲状旁腺激素(PTH)水平升高进入厦门大学附属中山医院接受99 mTc-甲氧基异丁基异腈(99 mTc-MIBI)甲状旁腺SPECT/CT融合显像、双时相平面显像检查,并最终诊断为PHPT的患者150例,回顾性分析其临床资料,以手术病理检查结果或肿块穿刺洗脱液中检测到PTH水平明显升高为诊断金标准,分析病灶检出情况,综合评估SPECT/CT融合显像、双时相平面显像检查的诊断效能。结果:研究入组的150例患者中,进行切除手术的有148例(病理检查结果如下:甲状旁腺增生26例,甲状旁腺腺瘤119例,甲状旁腺腺癌1例,甲状旁腺不典型增生1例,甲状旁腺囊肿1例),其余2例患者在超声引导下进行穿刺,测定穿刺液PTH水平明显升高而进行射频消融术,术后1周复查PTH水平降至正常。150个病灶中,136个病灶位于正常旁腺区域,5个病灶位于胸骨或锁骨后方,5个病灶位于颈动脉鞘,4个病灶位于气管食管沟。SPECT/CT融合显像检查检出病灶148个,双时相平面显像检查检出病灶139个。SPECT/CT融合显像检查、双时相平面显像检查对PHPT病灶诊断的准确率分别为98.67%、92.67%,差异有统计学意义(P<0.05)。结论:SPECT/CT融合显像检查在PHPT术前病灶定位诊断中具有更高的准确率,能有效识别异位病灶,为临床手术方案制定或介入治疗决策提供可靠依据,值得临床推广应用。 展开更多
关键词 原发性甲状旁腺功能亢进症 spect/ct融合显像检查 双时相平面显像检查 术前诊断
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基于临床特征、SPECT/CT脑灌注显像参数和颈动脉超声斑块特征的多因素模型对无症状性颈动脉狭窄患者认知功能下降的风险评估 被引量:1
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作者 王梦蝶 韩硕 +1 位作者 刘志翔 谢海 《中国卒中杂志》 北大核心 2025年第7期851-860,共10页
目的构建一个整合临床特征、SPECT/CT脑灌注显像参数和颈动脉超声斑块特征的多因素预测模型,用于评估无症状性颈动脉狭窄患者的认知功能下降风险。方法回顾性分析2021年1月1日—2022年12月31日在山东第二医科大学附属医院就诊的无症状... 目的构建一个整合临床特征、SPECT/CT脑灌注显像参数和颈动脉超声斑块特征的多因素预测模型,用于评估无症状性颈动脉狭窄患者的认知功能下降风险。方法回顾性分析2021年1月1日—2022年12月31日在山东第二医科大学附属医院就诊的无症状性颈动脉狭窄患者,所有患者在就诊时均完成以下评估:采用SPECT/CT脑灌注显像评估全脑平均局部脑血流量(regional cerebral blood flow,rCBF),通过颈动脉超声检查评估斑块面积及回声特征,使用MoCA进行认知功能评估并在随访1年后评估认知功能变化。以1年随访期间MoCA评分下降2分或以上为认知功能下降,将患者分为认知功能下降组和非认知功能下降组。进行单因素和多因素logistic回归分析以识别认知功能下降的独立危险因素,构建预测模型,并应用ROC曲线评估模型的预测效能。结果共纳入80例患者,其中35例(43.75%)在1年随访期间出现认知功能下降。高血压病史比例(62.9%vs.35.6%,P=0.016)、全脑平均rCBF(0.82±0.09 vs.0.93±0.08,P<0.001)、不对称指数(asymmetry i ndex,AI)([8.2±2.1)%vs.(5.9±1.8)%,P<0.001]、斑块面积([24.3±7.6)mm^(2)vs.(17.8±6.5)mm^(2),P<0.001]和低回声斑块比例(62.9%vs.24.4%,P=0.012)在认知功能下降组与非认知功能下降组间的差异具有统计学意义。多因素logistic回归分析显示,有高血压病史(OR 2.68,95%CI 1.07~6.71,P=0.035)、rCBF<0.85(OR 2.79,95%CI 1.08~7.21,P=0.034)、AI>7%(OR 3.00,95%CI 1.15~7.82,P=0.025)、斑块面积≥20 mm^(2)(OR 2.86,95%CI 1.09~7.52,P=0.033)和存在低回声斑块(OR 2.95,95%CI 1.17~7.44,P=0.022)是认知功能下降的独立危险因素。基于上述5个因素构建的认知功能下降风险预测模型,其ROC曲线的AUC为0.836(95%CI 0.752~0.920,P<0.001),敏感度为0.725,特异度为0.850。危险因素组合分析显示,四因素模型(有高血压病史、rCBF<0.85、AI>7%和斑块面积≥20 mm^(2))与五因素模型(有高血压病史、rCBF<0.85、AI>7%、斑块面积≥20 mm^(2)、存在低回声斑块)的预测效能相近(AUC分别为0.821和0.836)。结论本研究建立的多因素预测模型,整合了临床特征、SPECT/CT脑灌注显像参数和颈动脉超声斑块特征,可有效预测无症状性颈动脉狭窄患者认知功能下降风险,为临床风险评估和早期干预提供参考。 展开更多
关键词 颈动脉狭窄 认知功能下降 spect/ct脑灌注显像 颈动脉超声 预测模型
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^(99m)Tc-MIBI SPECT/CT联合半定量分析在甲状旁腺功能亢进症术前诊断中的应用
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作者 陈暐 饶胜芳 +1 位作者 李军军 陈莉 《实用临床医学(江西)》 2025年第1期76-79,共4页
目的比较^(99m)Tc-甲氧基异丁基异腈(^(99m)Tc-MIBI)SPECT/CT断层融合显像及双时相显像在甲状旁腺功能亢进症(HPT)术前定位诊断中的价值,同时对断层融合显像中半定量分析的价值进行初步探讨。方法回顾性分析72例行甲状旁腺切除术患者的... 目的比较^(99m)Tc-甲氧基异丁基异腈(^(99m)Tc-MIBI)SPECT/CT断层融合显像及双时相显像在甲状旁腺功能亢进症(HPT)术前定位诊断中的价值,同时对断层融合显像中半定量分析的价值进行初步探讨。方法回顾性分析72例行甲状旁腺切除术患者的病例资料,以术后病理诊断为“金标准”,计算^(99m)Tc-MIBI SPECT/CT断层融合显像及双时相显像对HPT病灶检出的灵敏度和特异度,并初步分析病灶与正常组织的放射性计数比值(T/NT比值)与术前甲状旁腺激素(PTH)水平的关系。结果72例患者中共发现HPT病灶145枚,SPECT/CT断层融合显像和双时相显像检出病灶的灵敏度分别为82.76%(120/145)和65.52%(95/145),2种显像方法比较差异有统计学意义(P=0.001);SPECT/CT断层融合显像的特异度为85.71%(12/14),高于双时相显像特异度71.43%(10/14),但差异无统计学意义(P=0.505);T/NT比值与术前PTH水平呈正相关(r=0.451,P=0.002)。结论^(99m)Tc-MIBI SPECT/CT断层融合显像对HPT病灶的定位诊断有较高的灵敏度,T/NT比值与术前PTH呈正相关,对临床诊断有一定的参考价值。 展开更多
关键词 甲状旁腺功能亢进症 ^(99m)Tc-甲氧基异丁基异腈 spect/ct断层融合显像 半定量分析 术前甲状旁腺激素水平
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Improved image resolution on thoracic carcinomas by quantitative 18F-FDG coincidence SPECT/CT in comparison to 18F-FDG PET/CT 被引量:3
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作者 Yuming Zheng Chaoling Jin +4 位作者 Huijuan Cui Haojie Dai Jue Yan Pingping Han Bailing Hsu 《The Journal of Biomedical Research》 CAS CSCD 2020年第4期309-317,共9页
Currently,18F-FDG coincidence SPECT(Co-SPECT)/CT scan still serves as an important tool for diagnosis,staging,and evaluation of cancer treatment in developing countries.We implemented full physical corrections(FPC) to... Currently,18F-FDG coincidence SPECT(Co-SPECT)/CT scan still serves as an important tool for diagnosis,staging,and evaluation of cancer treatment in developing countries.We implemented full physical corrections(FPC) to Co-SPECT(quantitative Co-SPECT) to improve the image resolution and contrast along with the capability for image quantitation.FPC included attenuation,scatter,resolution recovery,and noise reduction.A standard NEMA phantom filled with 10:1 F-18 activity concentration ratio in spheres and background was utilized to evaluate image performance.Subsequently,15 patients with histologically confirmed thoracic carcinomas were included to undergo a 18 F-FDG Co-SPECT/CT scan followed by a 18 F-FDG PET/CT scan.Functional parameters as SUVmax,SUVmean,SULpeak,and MTV from both quantitative Co-SPECT and PET were analyzed.Image resolution of Co-SPECT for NEMA phantom was improved to reveal the smallest sphere from a diameter of 28 mm to 22 mm(17 mm for PET).The image contrast was enhanced from 1.7 to 6.32(6.69 for PET) with slightly degraded uniformity in background(3.1% vs.6.7%)(5.6% for PET).Patients’ SUVmax,SUVmean,SULpeak,and MTV measured from quantitative Co-SPECT were overall highly correlated with those from PET(r=0.82-0.88).Adjustment of the threshold of SUVmax and SUV to determine SUVmean and MTV did not further change the correlations with PET(r=0.81-0.88).Adding full physical corrections to Co-SPECT images can significantly improve image resolution and contrast to reveal smaller tumor lesions along with the capability to quantify functional parameters like PET/CT. 展开更多
关键词 18F-FDG coincidence spect/ct full physical corrections thoracic carcinomas image quantitation
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分化型甲状腺癌全切术并^(131)Ⅰ清甲治疗后SPECT/CT在残留甲状腺组织的诊断价值
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作者 艾媛 周婷 苏莉 《中国CT和MRI杂志》 2025年第12期26-29,共4页
目的 探讨分化型甲状腺癌(DTC)全切并^(131)Ⅰ清甲治疗后,SPECT/CT在残留甲状腺组织的诊断价值。方法 选择2020年9月2023年9月本院完成DTC全切术及术后^(131)Ⅰ清甲治疗的DTC患者103例为研究对象,分别统计其^(131)Ⅰ剂量与血清促甲状腺... 目的 探讨分化型甲状腺癌(DTC)全切并^(131)Ⅰ清甲治疗后,SPECT/CT在残留甲状腺组织的诊断价值。方法 选择2020年9月2023年9月本院完成DTC全切术及术后^(131)Ⅰ清甲治疗的DTC患者103例为研究对象,分别统计其^(131)Ⅰ剂量与血清促甲状腺激素(TSH)、甲状腺球蛋白(Tg)水平。所有病例均于^(131)Ⅰ清甲治疗后一年后行SPECT/CT检查,分析SP ECT/CT显像诊断残留甲状腺组织的准确性。结果103例完成DTC全切术及术后^(131)Ⅰ清甲治疗的.患者中,治疗后1年有残留甲状腺组织发生率为1456%(15/103)。残留组患者^(131)Ⅰ使用剂量以及血清TS.H、Tg水平高于未残留组,差异有统计学意义(P<005)。经Kappa一致性检验,SPECT/CT断层融合显像.诊断残留甲状腺组织的一致性较高(Kappa值为0706)。SPECT/CT断层融合显像诊断残留甲状腺组.织的准确度高于平面显像,差异有统计学意义(P<005);SPECT/CT平面显像、断层融合显像诊断残留甲状腺组.织的敏感度和特异度比较,差异无统计学意义(P>005)。结论SPECT/CT显像诊断DTC全切术后^(131)Ⅰ清甲治疗后残留甲状腺组织具有较高的临床价值。 展开更多
关键词 spect/ct 分化型甲状腺癌 ^(131)Ⅰ清甲治疗 残留甲状腺组织
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^(223)Ra SPECT/CT模型显像探索研究
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作者 李童童 王兰 +4 位作者 王子 陆忻雨 石珂清 楼菁菁 刘兴党 《核技术》 北大核心 2025年第3期83-92,共10页
探索Carlson模型、正电子发射计算机断层扫描/计算机断层成像(Positron Emission Tomography/Computed Tomography,PET/CT)模型、Hoffman 3D脑模型中^(223)Ra单光子发射计算机断层扫描/计算机断层成像(Single Photon Emission Computed ... 探索Carlson模型、正电子发射计算机断层扫描/计算机断层成像(Positron Emission Tomography/Computed Tomography,PET/CT)模型、Hoffman 3D脑模型中^(223)Ra单光子发射计算机断层扫描/计算机断层成像(Single Photon Emission Computed Tomography/Computed Tomography,SPECT/CT)成像参数的条件。在研究中,对Carlson模型、PET/CT模型、Hoffman 3D脑模型进行GE NM/CT 670 ES质量控制测试,并获取三种模型的质量控制标准图像,然后对这三种模型进行^(223)Ra SPECT/CT成像检查,将获得的图像与质量控制标准图像进行对比。研究结果显示:^(223)Ra SPECT/CT可以进行断层显像。Carlson模型^(223)Ra SPECT/CT图像线性尚可、均匀性一般,热区分辨率和冷区分辨率均为22.3 mm;PET/CT模型^(223)Ra SPECT/CT图像尚可,横断面、冠状面、矢状面图像融合匹配度及衰减校正离散度等指标与^(99)Tcm SPECT/CT质控图像有一定的差距;Hoffman脑模型^(223)Ra SPECT/CT图像显示脑沟回、基底节核团欠清晰,需要继续提高图像质量。实验结果表明:^(223)Ra SPECT/CT显像质量尚可,证明^(223)Ra SPECT/CT可在临床上对患者进行显像,但为了得到质量更好的图像,具体的显像参数条件还需要进一步探索。 展开更多
关键词 ^(223)Ra spect/ct Carlson模型 Hoffman 3D脑模型 临床显像
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^(131)I SPECT/CT显像联合血清癌胚抗原、NLR水平对分化型甲状腺癌术后复发的预测价值
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作者 毕甜甜 左玮玮 +1 位作者 张秀婷 马子媛 《临床和实验医学杂志》 2025年第22期2440-2443,共4页
目的分析^(131)I单光子发射计算机体层摄影(SPECT)/CT显像联合血清癌胚抗原、中性粒细胞/淋巴细胞比值(NLR)水平对分化型甲状腺癌(DTC)术后复发的预测价值。方法选取于2021年1月至2023年1月期间在邢台市中心医院接受诊治的106例DTC患者... 目的分析^(131)I单光子发射计算机体层摄影(SPECT)/CT显像联合血清癌胚抗原、中性粒细胞/淋巴细胞比值(NLR)水平对分化型甲状腺癌(DTC)术后复发的预测价值。方法选取于2021年1月至2023年1月期间在邢台市中心医院接受诊治的106例DTC患者进行回顾性研究分析,所有患者均已接受甲状腺全切或近全切手术,并于术后接受^(131)I清甲或清灶治疗,依据患者术后是否复发,将其分为复发组(n=30)和未复发组(n=76)。统计两组基础资料信息及^(131)I SPECT/CT显像情况、血清癌胚抗原、NLR水平;采用多因素Logistic回归分析探讨影响DTC术后复发的因素;采用受试者操作特征(ROC)曲线分析三者单独及联合检测对DTC术后复发的预测价值。结果复发组TNM分期为Ⅲ~Ⅳ期患者占比、^(131)I SPECT/CT显像阳性患者占比及血清癌胚抗原、NLR水平分别为70.00%、83.33%、(5.93±1.27)ng/mL、7.36±1.82,均高于未复发组[36.84%、42.11%、(4.12±0.85)ng/mL、5.48±1.04],差异均有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,TNM分期为Ⅲ~Ⅳ期、^(131)I SPECT/CT显像阳性及血清癌胚抗原、NLR水平升高均是DTC术后复发的独立危险因素(P<0.05)。ROC曲线分析结果显示,^(131)I SPECT/CT显像、血清癌胚抗原、NLR水平及3者联合均可用于DTC术后复发的预测,曲线下面积分别为0.719、0.865、0.702、0.917,联合检测评估DTC术后复发的效能明显高于单独检测。结论TNM分期、^(131)I SPECT/CT显像及血清癌胚抗原、NLR水平与DTC术后复发密切相关,且^(131)I SPECT/CT显像联合血清癌胚抗原、NLR水平在预测DTC术后复发方面的敏感度和特异度最高,具有一定临床价值。 展开更多
关键词 甲状腺肿瘤 复发 ^(131)I spect/ct显像 癌胚抗原 中性粒细胞/淋巴细胞比值
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SPECT/CT、超声分别联合血清甲状腺球蛋白诊断分化型甲状腺癌术后颈部淋巴结转移的价值
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作者 毛树怿 滚政荣 +3 位作者 黄东菲 张玲丽 刘柳芳 刘观鑫 《右江医学》 2025年第7期615-619,共5页
目的探讨131 I治疗后SPECT/CT显像与超声分别联合血清甲状腺球蛋白(Tg)对分化型甲状腺癌(DTC)术后颈部淋巴结转移的诊断价值并进行比较。方法回顾性纳入2017年8月至2022年12月于某医院接受手术及131 I治疗的380例DTC患者,所有病例均经... 目的探讨131 I治疗后SPECT/CT显像与超声分别联合血清甲状腺球蛋白(Tg)对分化型甲状腺癌(DTC)术后颈部淋巴结转移的诊断价值并进行比较。方法回顾性纳入2017年8月至2022年12月于某医院接受手术及131 I治疗的380例DTC患者,所有病例均经手术病理明确颈部淋巴结转移状态。以病理结果为诊断金标准,分析SPECT/CT、超声分别联合血清Tg对DTC术后颈部淋巴结转移的灵敏度、特异度及准确度等指标,并通过χ^(2)检验比较不同方法的诊断效能。结果颈部超声联合血清Tg的诊断灵敏度为90.0%(108/120),特异度为84.6%(220/260),准确度为86.3%(328/380);SPECT/CT联合血清Tg的灵敏度为93.3%(112/120),特异度为92.3%(240/260),准确度为92.6%(352/380)。两种联合诊断方法在灵敏度、特异度及准确度上均显著优于单一检查(均P<0.05),其中SPECT/CT联合血清Tg与病理结果的一致性极强(kappa=0.834,P<0.001)。结论131 I治疗后SPECT/CT显像联合血清Tg的诊断效能显著优于超声联合Tg方案,对DTC术后颈部淋巴结转移的精准诊断及临床决策具有重要指导价值,值得临床推广应用。 展开更多
关键词 分化型甲状腺癌 颈部淋巴结转移 甲状腺球蛋白 spect/ct显像 超声
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筛查乳腺肿瘤患者应用SPECT/CT分子影像T/B值的临床效果
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作者 翟元伟 黄晓波 +4 位作者 樊建刚 林志武 李涛 谢滔 钟晓梅 《标记免疫分析与临床》 2025年第9期1890-1894,共5页
目的 探讨乳腺肿瘤患者筛查中应用SPECT/CT分子影像T/B值的临床效果。方法 研究以本院疑似乳腺肿瘤患者作为研究样本,样本量筛选100例,收集时间点为2022年7月至2024年7月,分析100例患者的手术病理检查结果 ,统计分析不同性质乳腺肿瘤各... 目的 探讨乳腺肿瘤患者筛查中应用SPECT/CT分子影像T/B值的临床效果。方法 研究以本院疑似乳腺肿瘤患者作为研究样本,样本量筛选100例,收集时间点为2022年7月至2024年7月,分析100例患者的手术病理检查结果 ,统计分析不同性质乳腺肿瘤各时间点平面显像与SPECT断层显像的T/B值、乳腺恶性肿瘤不同分子分型的T/B值、乳腺恶性肿瘤的T/B值与临床病理特征的关系,并统计分析超声与SPECT/CT检查的诊断效能。结果 100例患者中,手术病理检查结果 显示,病理类型:恶性43例,占43.00%;良性57例,占57.00%。注射后1h、3h,乳腺恶性肿瘤患者的平面显像与SPECT断层显像的T/B值均高于乳腺良性肿瘤(P<0.05)。43例乳腺恶性肿瘤患者中,分子分型:Her-2阳性型、Luminal阳性型、三阴性型患者的T/B值(4.28±1.01、3.83±0.78、3.51±0.62)逐渐降低(F=2.352,P<0.05)。Her-2表达阳性患者的T/B值高于阴性患者(P<0.05)。SPECT/CT检查的诊断特异性高于超声检查(P<0.05)。结论 乳腺肿瘤患者筛查中应用SPECT/CT分子影像的特异性较超声检查好,更能将误诊率降低,对乳腺肿瘤进行早期诊断,将一些不必要的手术活检避免,且其显像半定量指标的鉴别诊断灵敏度高,且Her-2阳性型患者具有显著较高的T/B值,能够将有效依据提供给临床对乳腺恶性肿瘤分子分型及治疗的预测。 展开更多
关键词 乳腺肿瘤 spect/ct分子影像 T/B值 临床病理特征 诊断效能
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SPECT/CT在冠心病心肌缺血诊断中的应用进展
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作者 任庆余 孟庆乐 +3 位作者 张延华 吴兴 何钰鸿 陈甜甜 《中国医疗设备》 2025年第12期187-192,共6页
单光子发射计算机断层显像/计算机断层扫描(Single-Photon Emission Computed Tomography/Computed Tomography,SPECT/CT)是检测受检者静息状态及负荷状态下心肌血流灌注的重要手段,可以准确评估冠心病患者心肌缺血情况,具有良好的灵敏... 单光子发射计算机断层显像/计算机断层扫描(Single-Photon Emission Computed Tomography/Computed Tomography,SPECT/CT)是检测受检者静息状态及负荷状态下心肌血流灌注的重要手段,可以准确评估冠心病患者心肌缺血情况,具有良好的灵敏度和特异性,在冠心病诊断、危险度分层与预后评估等方面均有重要价值。SPECT/CT技术近年来取得了快速发展,在冠心病心肌缺血诊断中的应用越来越广泛,得到了普遍认可,但是部分人员对此了解不足,限制了其发展。本文综述了SPECT/CT显像剂主要类型特点、显像方法进展与优化及其在冠心病心肌缺血诊断中的应用,并对未来相关发展方向进行展望,以期提高医务人员对该方面的认识水平,扩大SPECT/CT在冠心病心肌缺血中的应用。 展开更多
关键词 单光子发射计算机断层显像/计算机断层扫描(spect/ct) 心肌灌注显像 冠心病 心肌缺血 显像剂 显像方法
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