In general, the overall goals for musical education in colleges include but are not limited to, to make the students become talents with ability to adapt specialized requirements by state, capacity to perform with art...In general, the overall goals for musical education in colleges include but are not limited to, to make the students become talents with ability to adapt specialized requirements by state, capacity to perform with artistic doctrines, capability to solve problems in teaching and research, ability to adapt to reform in musical education at schools, and ability to promote music in society.Based on examination of history of musical education, and reference by contemporary authors, this paper intends to elaborate basic speciality structure for musical education students by approaches of analysis, deduction and induction and so on and so forth. The paper mainly focus on the necessity, importance, practical nature and relevance. Particular attention has been paid to model called ＂speciality plus versatility＂ based on advice from students, schools and society as well.展开更多
Curriculum-based ideological and political education is the inevitable requirement of constructing the pattern of ideological and political education in the new era.As the main leader and implementer of curriculum-bas...Curriculum-based ideological and political education is the inevitable requirement of constructing the pattern of ideological and political education in the new era.As the main leader and implementer of curriculum-based ideological and political education in vocational colleges,speciality teachers should take the fundamental task of moral education as the guidance,focus on it through curriculum,promote the organic unity of knowledge teaching,skill improvement and value guidance in the teaching process,and finally form a new ideological and political work mode in line with the requirements of“high-level vocational college and speciality”construction.At present,speciality teachers in vocational colleges have some problems in curriculum-based ideological and political education,which is mainly reflected in some speciality teachers’weak self-consciousness,poor understanding and integration ability.In order to effectively solve the problem,they have to establish the curriculum-based ideological and political education promotion mechanism led by the college Party committee,consolidate the institutional guarantee for speciality teachers in moral education,strengthen their consciousness and awareness,innovate and improve the assessment and evaluation mechanism of their dedicated education.展开更多
The transcriptional cascade and regulatory loop play crucial roles in regulating plant-specialized metabolite biosynthesis.Capsaicinoids are unique to the genus Capsicum and confer a pungent flavor to its fruits.Howev...The transcriptional cascade and regulatory loop play crucial roles in regulating plant-specialized metabolite biosynthesis.Capsaicinoids are unique to the genus Capsicum and confer a pungent flavor to its fruits.However,the transcriptional regulation of capsaicinoid biosynthesis remains largely unknown.In this study,two AP2/ERF transcription factors(TFs),CaERF102 and CaERF111,were characterized for their role in the capsaicinoid biosynthesis process.Expression analysis of two ERFs and capsaicinoid biosynthetic genes(CBGs)suggested that they were associated with capsaicinoid biosynthesis.Both ERFs encode nuclear-localized proteins and function as transcriptional activators through their C-terminal activation motifs.The two ERF TFs participated in capsaicinoid biosynthesis by directly activating the promoters of key CBGs,and this activation was significantly enhanced when CaMYC2 was co-expressed.Moreover,CaERF102 and CaERF111 were found to interact with CaMYC2.This study helps elucidate the AP2/ERF TF regulatory network that governs capsaicinoid biosynthesis in Capsicum species.展开更多
The operation of deep-sea underwater vehicles relies entirely on onboard batteries.However,the extreme deep-sea conditions,characterized by ultrahigh hydraulic pressure,low temperature,and seawater conductivity,pose s...The operation of deep-sea underwater vehicles relies entirely on onboard batteries.However,the extreme deep-sea conditions,characterized by ultrahigh hydraulic pressure,low temperature,and seawater conductivity,pose significant challenges for battery development.These conditions drive the need for specialized designs in deep-sea batteries,incorporating critical aspects of power generation,protection,distribution,and management.Over time,deep-sea battery technology has evolved through multiple generations,with lithium(Li)batteries emerging in recent decades as the preferred power source due to their high energy and reduced operational risks.Although the rapid progress of Li batteries has notably advanced the capabilities of underwater vehicles,critical technical issues remain unresolved.This review first systematically presents the whole picture of deep-sea battery manufacturing,focusing on Li batteries as the current mainstream solution for underwater power.It examines the key aspects of deep-sea Li battery development,including materials selection informed by electro-chemo-mechanics models,component modification and testing,and battery management systems specialized in software and hardware.Finally,it discusses the main challenges limiting the utilization of deep-sea batteries and outlines promising directions for future development.Based on the systematic reflection on deep-sea batteries and discussion on deep-sea Li batteries,this review aims to provide a research foundation for developing underwater power tailored for extreme environmental exploration.展开更多
Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment o...Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer's disease to prevent/stop inflammation and combat disease pathology. Therefore, it is important to clarify whether they counteract the expression of genes and proteins induced by amyloid-β. With this objective, we analyzed the relevance of human monocyte–derived microglia for in vitro modeling of neuroinflammation and its resolution in the context of Alzheimer's disease and investigated the pro-resolving bioactivity of maresin 1 on amyloid-β42–induced Alzheimer's disease–like inflammation. Analysis of RNA-sequencing data and secreted proteins in supernatants from the monocyte-derived microglia showed that the monocyte-derived microglia resembled Alzheimer's disease–like neuroinflammation in human brain microglia after incubation with amyloid-β42. Maresin 1 restored homeostasis by down-regulating inflammatory pathway related gene expression induced by amyloid-β42 in monocyte-derived microglia, protection of maresin 1 against the effects of amyloid-β42 is mediated by a re-balancing of inflammatory transcriptional networks in which modulation of gene transcription in the nuclear factor-kappa B pathway plays a major part. We pinpointed molecular targets that are associated with both neuroinflammation in Alzheimer's disease and therapeutic targets by maresin 1. In conclusion, monocyte-derived microglia represent a relevant in vitro microglial model for studies on Alzheimer's disease-like inflammation and drug response for individual patients. Maresin 1 ameliorates amyloid-β42–induced changes in several genes of importance in Alzheimer's disease, highlighting its potential as a therapeutic target for Alzheimer's disease.展开更多
The pathophysiology of ischemic stroke is complex and multifactorial,involving various forms of cell death such as apoptosis,autophagy,and necrosis.A recent study suggests that oxidative and inflammatory stress can in...The pathophysiology of ischemic stroke is complex and multifactorial,involving various forms of cell death such as apoptosis,autophagy,and necrosis.A recent study suggests that oxidative and inflammatory stress can induce ferroptosis,a specialized form of cell death characterized by the accumulation of lipid peroxides dependent on intracellular iron overload(Li and Jia,2023).展开更多
The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods fo...The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods for centroid measurement often necessitate custom equipment and specialized positioning devices,leading to high costs and limited accuracy.Here,we present a centroid measurement method that integrates 3D scanning technology,enabling accurate measurement of centroid across various types of objects without the need for specialized positioning fixtures.A theoretical framework for centroid measurement was established,which combined the principle of the multi-point weighing method with 3D scanning technology.The measurement accuracy was evaluated using a designed standard component.Experimental results demonstrate that the discrepancies between the theoretical and the measured centroid of a standard component with various materials and complex shapes in the X,Y,and Z directions are 0.003 mm,0.009 mm,and 0.105 mm,respectively,yielding a spatial deviation of 0.106 mm.Qualitative verification was conducted through experimental validation of three distinct types.They confirmed the reliability of the proposed method,which allowed for accurate centroid measurements of various products without requiring positioning fixtures.This advancement significantly broadened the applicability and scope of centroid measurement devices,offering new theoretical insights and methodologies for the measurement of complex parts and systems.展开更多
Introduction Types of paper Contributions falling into the following categories will be considered forpublication:Reviewsarticle(>10000words),Shortreview(~5000words),Featurearticle(>8000words),Researchpaper,Shor...Introduction Types of paper Contributions falling into the following categories will be considered forpublication:Reviewsarticle(>10000words),Shortreview(~5000words),Featurearticle(>8000words),Researchpaper,Short communication (~3000 words), Commentary (~1000 words),and Viewpiont(~3000words).Please ensure that you select the appropriate article type from the list of options when makingyour submission. Authors contributing to special issues should ensure that they select the special issue article type from this list.展开更多
BACKGROUND Postmenopausal women with osteoporosis are at high risk of developing depre-ssive symptoms,necessitating specialized psychological nursing interventions.AIM To investigate factors influencing depressive sym...BACKGROUND Postmenopausal women with osteoporosis are at high risk of developing depre-ssive symptoms,necessitating specialized psychological nursing interventions.AIM To investigate factors influencing depressive symptoms in postmenopausal women with osteoporosis and develop targeted psychological nursing interven-tions.METHODS A total of 180 postmenopausal women with osteoporosis admitted to the Depar-tment of Orthopedics at the First Affiliated Hospital of Soochow University between October 2021 and October 2024 were selected as research participants.Information on age,duration of menopause,body mass index,education level,marital status,activity intensity,bone density,presence of chronic diseases,calcium supplement intake,sex hormone levels,and depressive symptoms were collected.The 24-item Hamilton Depression Scale was used for assessment.RESULTS Forty-eight patients had no depressive symptoms,and 132 patients had depre-ssive symptoms.Comprehensive univariate and multivariate logistic regression analyses showed that low bone density in the lumbar spine(L2-L4)and femoral neck,presence of chronic diseases,and low 5-hydroxytryptamine levels were independent risk factors for depressive symptoms,whereas calcium supplement intake and moderate to high-intensity activity were independent protective factors.CONCLUSION By implementing specialized psychological nursing interventions,and providing rehabilitation guidance,the incidence of depressive symptoms can be effectively reduced,improving the psychological health status and patient quality of life.展开更多
My favorite TV series is Stranger Things.It is a popular American science fiction drama.The story takes place in a small town in the1980s.A young b oy named W ill mysteriously disappears.His friends,family,and the pol...My favorite TV series is Stranger Things.It is a popular American science fiction drama.The story takes place in a small town in the1980s.A young b oy named W ill mysteriously disappears.His friends,family,and the police start to search for answers.As they look for Will,they find something strange:there are some mysterious forces and a girl with special powers.展开更多
Introduction Types of paper Contributions falling into the following categories will be considered forpublication:Reviewsarticle(>10000words),Shortreview(~5000words),Featurearticle(>8000words),Researchpaper,Shor...Introduction Types of paper Contributions falling into the following categories will be considered forpublication:Reviewsarticle(>10000words),Shortreview(~5000words),Featurearticle(>8000words),Researchpaper,Short communication (~3000 words), Commentary (~1000 words),and Viewpiont(~3000words).Pleaseensurethatyouselectthe appropriatearticletypefromthelistofoptionswhenmakingyour submission. Authors contributing to special issues should ensure that they select the special issue article type from this list.展开更多
Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews article (>10000 words),Short review(~5000 words),Feature article (>8000 words),Research ...Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews article (>10000 words),Short review(~5000 words),Feature article (>8000 words),Research paper,Short communication (~3000 words),Commentary (~1000 words),and Viewpiont (~3000 words).Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.展开更多
Floral color and scent are crucial for plant-environment interactions,especially in reproduction by attracting pollinators for fertilization.They also have wide applications in cosmetic,pharmaceutical,and nutraceutica...Floral color and scent are crucial for plant-environment interactions,especially in reproduction by attracting pollinators for fertilization.They also have wide applications in cosmetic,pharmaceutical,and nutraceutical industries.Plant pigments are typically classified as chlorophylls,flavonoids,carotenoids,and betalains,while volatile organic compounds(VOCs)are grouped as terpenes,phenylpropanoids/benzenoids,and fatty acid derivatives.Significant progresses have been made in understanding the biosynthesis and regulation of these floral pigments and VOCs.Despite differences in their biosynthetic pathways,floral pigments and VOCs are biochemically connected and exhibit synergistic interactions during flower development and in response to biotic and abiotic stresses,suggesting the existence of pleiotropic regulators or complex mechanisms co-regulating their biosynthesis.In this review,we summarize and outline the metabolite pathways mainly integrating flavonoids,carotenoids,terpenes,and phenylpropanoids/benzenoids.We also provide a series of scenarios illustrating the coordinated regulation of floral color and scent.Finally,we suggest areas for future research.We hope this review will spark interest in this research direction and stimulate further studies.展开更多
Objective:To compare the nursing effects of routine care and specialized nursing intervention on patients with dysphagia during acute stroke.Methods:A total of 188 patients with acute stroke and dysphagia who received...Objective:To compare the nursing effects of routine care and specialized nursing intervention on patients with dysphagia during acute stroke.Methods:A total of 188 patients with acute stroke and dysphagia who received treatment at our hospital from May 2022 to December 2024 were selected as study subjects.The patients were randomly divided into a control group and an observation group,with 94 patients in each group.The control group received routine nursing intervention,while the observation group received specialized nursing intervention.The general information,swallowing function,quality of life,and nursing satisfaction were compared between the two groups.Results:There was no statistically significant difference in general information between the two groups(P>0.05).The SAS score of the observation group after nursing was significantly lower than that of the control group(t=19.463,P=0.000<0.001).After intervention,the number of patients with lung infection in the observation group was significantly lower than that in the control group(χ2=7.309,P=0.007<0.01).The overall quality of life score of the observation group was significantly better than that of the control group after intervention(P<0.001).The nursing satisfaction of the observation group was significantly higher than that of the control group(χ^(2)=15.865,P=0.000<0.001).Conclusion:Compared with routine care,specialized nursing intervention can effectively improve the swallowing function of patients with dysphagia during acute stroke,enhance their quality of life,and increase nursing satisfaction.展开更多
Established in 1958,Sichuan Academy of Social Sciences(SASS)is a public institutionguided by the People’s Government of Sichuan Province.It is a comprehensive and specializedresearch institution in social sciences th...Established in 1958,Sichuan Academy of Social Sciences(SASS)is a public institutionguided by the People’s Government of Sichuan Province.It is a comprehensive and specializedresearch institution in social sciences that integrates research,education,editing,andconsulting services.It holds the registered trademark of“Tianfu Think Tank”and owns twocampuses:Baihuatan and Banzhuyuan.SASS consists of 16 research institutes as well as functional and educational departments,such as the Party Committee and the Graduate School.Currently,it has 459 employees,including a significant number of reputable scholars and recipients of national and provincial honors in the fields of culture and economy,such as national-level candidates for the Hundred,Thousand and Ten Thousand Talents Project,Leading Talent in Philosophy and Social Sciences in the National Ten Thousand Talents Program,participants in China’s Four-pronged Publicity Talent Program,Academic and Technology Leader of Sichuan Province,and Expert of Sichuan Province with Outstanding Contributions.展开更多
Mechanical ventilation is a specialized oxygen therapy and life support technology with significant importance for critically ill patients. In fact, 40%–66% of patients in the intensive care unit(ICU) require mechani...Mechanical ventilation is a specialized oxygen therapy and life support technology with significant importance for critically ill patients. In fact, 40%–66% of patients in the intensive care unit(ICU) require mechanical ventilation.^([1,2]) However, the mechanical ventilation can lead to ventilatorassociated lung injury(VALI),^([3]) ultimately resulting in difficulties in weaning from mechanical ventilation,prolonged hospital stays, and even increased mortality.展开更多
Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews article(>10000 words),Short review(~5000 words),Feature article(>8000 words),Research pa...Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews article(>10000 words),Short review(~5000 words),Feature article(>8000 words),Research paper,Short communication(~3000 words),Commentary(~1000 words),and Viewpiont(~3000 words).Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.展开更多
INTRODUCTION Types of paper Contributions falling into the following categories will be considered for publication:Original research papers,reviews and short communications.Please ensure that you select the appropriat...INTRODUCTION Types of paper Contributions falling into the following categories will be considered for publication:Original research papers,reviews and short communications.Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.展开更多
Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews,Technical papers,Theoretical papers,and Editorial.Please ensure that you select the appropriat...Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews,Technical papers,Theoretical papers,and Editorial.Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.展开更多
文摘In general, the overall goals for musical education in colleges include but are not limited to, to make the students become talents with ability to adapt specialized requirements by state, capacity to perform with artistic doctrines, capability to solve problems in teaching and research, ability to adapt to reform in musical education at schools, and ability to promote music in society.Based on examination of history of musical education, and reference by contemporary authors, this paper intends to elaborate basic speciality structure for musical education students by approaches of analysis, deduction and induction and so on and so forth. The paper mainly focus on the necessity, importance, practical nature and relevance. Particular attention has been paid to model called ＂speciality plus versatility＂ based on advice from students, schools and society as well.
基金Shen Yue(1982-),female,an associate professor with master degree,teaching English in School of Applied Foreign Languages,Zhejiang Yuexiu University,Shaoxing,Zhejiang,China.Email:sy0416sy@163.com。
文摘Curriculum-based ideological and political education is the inevitable requirement of constructing the pattern of ideological and political education in the new era.As the main leader and implementer of curriculum-based ideological and political education in vocational colleges,speciality teachers should take the fundamental task of moral education as the guidance,focus on it through curriculum,promote the organic unity of knowledge teaching,skill improvement and value guidance in the teaching process,and finally form a new ideological and political work mode in line with the requirements of“high-level vocational college and speciality”construction.At present,speciality teachers in vocational colleges have some problems in curriculum-based ideological and political education,which is mainly reflected in some speciality teachers’weak self-consciousness,poor understanding and integration ability.In order to effectively solve the problem,they have to establish the curriculum-based ideological and political education promotion mechanism led by the college Party committee,consolidate the institutional guarantee for speciality teachers in moral education,strengthen their consciousness and awareness,innovate and improve the assessment and evaluation mechanism of their dedicated education.
基金funded by the National Natural Science Foundation of China(Grant Nos.32202502,U21A20230,32070331,32102380 and 32072580)National Key Research and Development Program(Grant No.2018YFD1000800)+3 种基金the Key-Area Research and Development Program of Guangdong Province(Grant No.2022B0202080001)the Special Fund for Seed Industry of Guangdong Province Rural Revitalization Strategy(Grant No.2022-NPY00-024)Tibet Autonomous Region of Lhasa City Science and Technology Project(Grant No.LSKJ202310)the Science and Technology Project of Bijie City(Grant No.BKK2022-3)。
文摘The transcriptional cascade and regulatory loop play crucial roles in regulating plant-specialized metabolite biosynthesis.Capsaicinoids are unique to the genus Capsicum and confer a pungent flavor to its fruits.However,the transcriptional regulation of capsaicinoid biosynthesis remains largely unknown.In this study,two AP2/ERF transcription factors(TFs),CaERF102 and CaERF111,were characterized for their role in the capsaicinoid biosynthesis process.Expression analysis of two ERFs and capsaicinoid biosynthetic genes(CBGs)suggested that they were associated with capsaicinoid biosynthesis.Both ERFs encode nuclear-localized proteins and function as transcriptional activators through their C-terminal activation motifs.The two ERF TFs participated in capsaicinoid biosynthesis by directly activating the promoters of key CBGs,and this activation was significantly enhanced when CaMYC2 was co-expressed.Moreover,CaERF102 and CaERF111 were found to interact with CaMYC2.This study helps elucidate the AP2/ERF TF regulatory network that governs capsaicinoid biosynthesis in Capsicum species.
基金support provided by National Key Research and Development Program of China(2023YFE0203000 and 2016YFC0300200)the NSAF(Grant No.U2330205)+3 种基金Full-Sea-Depth Battery Project(2020-XXXX-XX-246-00)Open project of Shaanxi Laboratory of Aerospace Power(2022ZY2-JCYJ-01-09)Fundamental Research Funds for the Central Universities,ND Basic Research Funds(G2022WD)the Innovation Team of Shaanxi Province。
文摘The operation of deep-sea underwater vehicles relies entirely on onboard batteries.However,the extreme deep-sea conditions,characterized by ultrahigh hydraulic pressure,low temperature,and seawater conductivity,pose significant challenges for battery development.These conditions drive the need for specialized designs in deep-sea batteries,incorporating critical aspects of power generation,protection,distribution,and management.Over time,deep-sea battery technology has evolved through multiple generations,with lithium(Li)batteries emerging in recent decades as the preferred power source due to their high energy and reduced operational risks.Although the rapid progress of Li batteries has notably advanced the capabilities of underwater vehicles,critical technical issues remain unresolved.This review first systematically presents the whole picture of deep-sea battery manufacturing,focusing on Li batteries as the current mainstream solution for underwater power.It examines the key aspects of deep-sea Li battery development,including materials selection informed by electro-chemo-mechanics models,component modification and testing,and battery management systems specialized in software and hardware.Finally,it discusses the main challenges limiting the utilization of deep-sea batteries and outlines promising directions for future development.Based on the systematic reflection on deep-sea batteries and discussion on deep-sea Li batteries,this review aims to provide a research foundation for developing underwater power tailored for extreme environmental exploration.
基金supported by the China Scholarship Council(to YW)the Swedish Research Council,No.2018-02601(to MS)+7 种基金the Alzheimer Foundation,No.AF-980695(to MS)the Stockholm County Council,No.RS2020-0731(to MS)the Foundation of Old Servants(to MS)the Gun and Bertil Stohne Foundation(to MS)the?hlén Foundation,No.233055(to MS)The Swedish Fund for Research without Animal Experiments(to MS)the Swedish Dementia Foundation(to MS)the Brain foundation,No.FO2022-0131(to MS)。
文摘Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer's disease to prevent/stop inflammation and combat disease pathology. Therefore, it is important to clarify whether they counteract the expression of genes and proteins induced by amyloid-β. With this objective, we analyzed the relevance of human monocyte–derived microglia for in vitro modeling of neuroinflammation and its resolution in the context of Alzheimer's disease and investigated the pro-resolving bioactivity of maresin 1 on amyloid-β42–induced Alzheimer's disease–like inflammation. Analysis of RNA-sequencing data and secreted proteins in supernatants from the monocyte-derived microglia showed that the monocyte-derived microglia resembled Alzheimer's disease–like neuroinflammation in human brain microglia after incubation with amyloid-β42. Maresin 1 restored homeostasis by down-regulating inflammatory pathway related gene expression induced by amyloid-β42 in monocyte-derived microglia, protection of maresin 1 against the effects of amyloid-β42 is mediated by a re-balancing of inflammatory transcriptional networks in which modulation of gene transcription in the nuclear factor-kappa B pathway plays a major part. We pinpointed molecular targets that are associated with both neuroinflammation in Alzheimer's disease and therapeutic targets by maresin 1. In conclusion, monocyte-derived microglia represent a relevant in vitro microglial model for studies on Alzheimer's disease-like inflammation and drug response for individual patients. Maresin 1 ameliorates amyloid-β42–induced changes in several genes of importance in Alzheimer's disease, highlighting its potential as a therapeutic target for Alzheimer's disease.
文摘The pathophysiology of ischemic stroke is complex and multifactorial,involving various forms of cell death such as apoptosis,autophagy,and necrosis.A recent study suggests that oxidative and inflammatory stress can induce ferroptosis,a specialized form of cell death characterized by the accumulation of lipid peroxides dependent on intracellular iron overload(Li and Jia,2023).
基金supported by National Natural Science Foundation of China(No.52176122).
文摘The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods for centroid measurement often necessitate custom equipment and specialized positioning devices,leading to high costs and limited accuracy.Here,we present a centroid measurement method that integrates 3D scanning technology,enabling accurate measurement of centroid across various types of objects without the need for specialized positioning fixtures.A theoretical framework for centroid measurement was established,which combined the principle of the multi-point weighing method with 3D scanning technology.The measurement accuracy was evaluated using a designed standard component.Experimental results demonstrate that the discrepancies between the theoretical and the measured centroid of a standard component with various materials and complex shapes in the X,Y,and Z directions are 0.003 mm,0.009 mm,and 0.105 mm,respectively,yielding a spatial deviation of 0.106 mm.Qualitative verification was conducted through experimental validation of three distinct types.They confirmed the reliability of the proposed method,which allowed for accurate centroid measurements of various products without requiring positioning fixtures.This advancement significantly broadened the applicability and scope of centroid measurement devices,offering new theoretical insights and methodologies for the measurement of complex parts and systems.
文摘Introduction Types of paper Contributions falling into the following categories will be considered forpublication:Reviewsarticle(>10000words),Shortreview(~5000words),Featurearticle(>8000words),Researchpaper,Short communication (~3000 words), Commentary (~1000 words),and Viewpiont(~3000words).Please ensure that you select the appropriate article type from the list of options when makingyour submission. Authors contributing to special issues should ensure that they select the special issue article type from this list.
文摘BACKGROUND Postmenopausal women with osteoporosis are at high risk of developing depre-ssive symptoms,necessitating specialized psychological nursing interventions.AIM To investigate factors influencing depressive symptoms in postmenopausal women with osteoporosis and develop targeted psychological nursing interven-tions.METHODS A total of 180 postmenopausal women with osteoporosis admitted to the Depar-tment of Orthopedics at the First Affiliated Hospital of Soochow University between October 2021 and October 2024 were selected as research participants.Information on age,duration of menopause,body mass index,education level,marital status,activity intensity,bone density,presence of chronic diseases,calcium supplement intake,sex hormone levels,and depressive symptoms were collected.The 24-item Hamilton Depression Scale was used for assessment.RESULTS Forty-eight patients had no depressive symptoms,and 132 patients had depre-ssive symptoms.Comprehensive univariate and multivariate logistic regression analyses showed that low bone density in the lumbar spine(L2-L4)and femoral neck,presence of chronic diseases,and low 5-hydroxytryptamine levels were independent risk factors for depressive symptoms,whereas calcium supplement intake and moderate to high-intensity activity were independent protective factors.CONCLUSION By implementing specialized psychological nursing interventions,and providing rehabilitation guidance,the incidence of depressive symptoms can be effectively reduced,improving the psychological health status and patient quality of life.
文摘My favorite TV series is Stranger Things.It is a popular American science fiction drama.The story takes place in a small town in the1980s.A young b oy named W ill mysteriously disappears.His friends,family,and the police start to search for answers.As they look for Will,they find something strange:there are some mysterious forces and a girl with special powers.
文摘Introduction Types of paper Contributions falling into the following categories will be considered forpublication:Reviewsarticle(>10000words),Shortreview(~5000words),Featurearticle(>8000words),Researchpaper,Short communication (~3000 words), Commentary (~1000 words),and Viewpiont(~3000words).Pleaseensurethatyouselectthe appropriatearticletypefromthelistofoptionswhenmakingyour submission. Authors contributing to special issues should ensure that they select the special issue article type from this list.
文摘Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews article (>10000 words),Short review(~5000 words),Feature article (>8000 words),Research paper,Short communication (~3000 words),Commentary (~1000 words),and Viewpiont (~3000 words).Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.
基金supported by the National Natural Science Foundation of China(Grant Nos.32272751,32272750,31972445)the Department of Science and Technology of Jilin Province(Grant Nos.20220508112RC,20210101005JC)+1 种基金the“Pioneer”and“Leading Goose”R&D Program of Zhejiang(Grant No.2023C02028)the China Scholarship Council(Grant No.202006625007)。
文摘Floral color and scent are crucial for plant-environment interactions,especially in reproduction by attracting pollinators for fertilization.They also have wide applications in cosmetic,pharmaceutical,and nutraceutical industries.Plant pigments are typically classified as chlorophylls,flavonoids,carotenoids,and betalains,while volatile organic compounds(VOCs)are grouped as terpenes,phenylpropanoids/benzenoids,and fatty acid derivatives.Significant progresses have been made in understanding the biosynthesis and regulation of these floral pigments and VOCs.Despite differences in their biosynthetic pathways,floral pigments and VOCs are biochemically connected and exhibit synergistic interactions during flower development and in response to biotic and abiotic stresses,suggesting the existence of pleiotropic regulators or complex mechanisms co-regulating their biosynthesis.In this review,we summarize and outline the metabolite pathways mainly integrating flavonoids,carotenoids,terpenes,and phenylpropanoids/benzenoids.We also provide a series of scenarios illustrating the coordinated regulation of floral color and scent.Finally,we suggest areas for future research.We hope this review will spark interest in this research direction and stimulate further studies.
文摘Objective:To compare the nursing effects of routine care and specialized nursing intervention on patients with dysphagia during acute stroke.Methods:A total of 188 patients with acute stroke and dysphagia who received treatment at our hospital from May 2022 to December 2024 were selected as study subjects.The patients were randomly divided into a control group and an observation group,with 94 patients in each group.The control group received routine nursing intervention,while the observation group received specialized nursing intervention.The general information,swallowing function,quality of life,and nursing satisfaction were compared between the two groups.Results:There was no statistically significant difference in general information between the two groups(P>0.05).The SAS score of the observation group after nursing was significantly lower than that of the control group(t=19.463,P=0.000<0.001).After intervention,the number of patients with lung infection in the observation group was significantly lower than that in the control group(χ2=7.309,P=0.007<0.01).The overall quality of life score of the observation group was significantly better than that of the control group after intervention(P<0.001).The nursing satisfaction of the observation group was significantly higher than that of the control group(χ^(2)=15.865,P=0.000<0.001).Conclusion:Compared with routine care,specialized nursing intervention can effectively improve the swallowing function of patients with dysphagia during acute stroke,enhance their quality of life,and increase nursing satisfaction.
文摘Established in 1958,Sichuan Academy of Social Sciences(SASS)is a public institutionguided by the People’s Government of Sichuan Province.It is a comprehensive and specializedresearch institution in social sciences that integrates research,education,editing,andconsulting services.It holds the registered trademark of“Tianfu Think Tank”and owns twocampuses:Baihuatan and Banzhuyuan.SASS consists of 16 research institutes as well as functional and educational departments,such as the Party Committee and the Graduate School.Currently,it has 459 employees,including a significant number of reputable scholars and recipients of national and provincial honors in the fields of culture and economy,such as national-level candidates for the Hundred,Thousand and Ten Thousand Talents Project,Leading Talent in Philosophy and Social Sciences in the National Ten Thousand Talents Program,participants in China’s Four-pronged Publicity Talent Program,Academic and Technology Leader of Sichuan Province,and Expert of Sichuan Province with Outstanding Contributions.
文摘Mechanical ventilation is a specialized oxygen therapy and life support technology with significant importance for critically ill patients. In fact, 40%–66% of patients in the intensive care unit(ICU) require mechanical ventilation.^([1,2]) However, the mechanical ventilation can lead to ventilatorassociated lung injury(VALI),^([3]) ultimately resulting in difficulties in weaning from mechanical ventilation,prolonged hospital stays, and even increased mortality.
文摘Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews article(>10000 words),Short review(~5000 words),Feature article(>8000 words),Research paper,Short communication(~3000 words),Commentary(~1000 words),and Viewpiont(~3000 words).Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.
文摘INTRODUCTION Types of paper Contributions falling into the following categories will be considered for publication:Original research papers,reviews and short communications.Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.
文摘Introduction Types of paper Contributions falling into the following categories will be considered for publication:Reviews,Technical papers,Theoretical papers,and Editorial.Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.
