对于当前植保无人机喷洒存在重复喷洒、农药残留、缺少在线病虫害检测,且检测方法不易在嵌入式端部署等问题,提出一种植保无人机平台下基于改进YOLOv7的霜霉病与潜叶蝇检测农药喷洒系统。首先,采用渐进金字塔网络AFPN提升模型在特征融...对于当前植保无人机喷洒存在重复喷洒、农药残留、缺少在线病虫害检测,且检测方法不易在嵌入式端部署等问题,提出一种植保无人机平台下基于改进YOLOv7的霜霉病与潜叶蝇检测农药喷洒系统。首先,采用渐进金字塔网络AFPN提升模型在特征融合区域的自适应特征融合能力。其次,引入EMA注意力机制模块,利用维度交互的方式来提升融合像素特征。试验结果表明,改进YOLOv7病虫害检测算法的平均精度均值mAP达到94.2%,相比于原始YOLOv7算法提高25.9%,每秒传输帧数FPS相比于原算法提高4.6%。最后,将YOLOv7—AFPN—EMA的病虫害识别模型部署到Jetson Orin Nano上进行验证性检测试验,对比模型改进前后的检测精度。验证结果表明,改进算法相比于原始算法,在线实时检测精度提升11.3%,病虫害检测成功率达89.7%。展开更多
Progressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss.Ferroptosis has been demonstrated to be associated with retinal deg...Progressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss.Ferroptosis has been demonstrated to be associated with retinal degenerative diseases.However,the molecular mechanisms underlying ferroptosis and photoreceptor cell death in age-related macular degeneration remain largely unexplored.Bioinformatics and biochemical analyses in this study revealed xC^(–),solute carrier family 7 member 11-regulated ferroptosis as the predominant pathological process of photoreceptor cell degeneration in a light-induced dry age-related macular degeneration mouse model.This process involves the nuclear factor-erythroid factor 2-related factor 2-solute carrier family 7 member 11-glutathione peroxidase 4 signaling pathway,through which cystine depletion,iron ion accumulation,and enhanced lipid peroxidation ultimately lead to photoreceptor cell death and subsequent visual function impairment.We demonstrated that solute carrier family 7 member 11 overexpression blocked this process by inhibiting oxidative stress in vitro and in vivo.Conversely,solute carrier family 7 member 11 knockdown or the solute carrier family 7 member 11 inhibitor sulfasalazine and ferroptosis-inducing agent erastin aggravated H_(2)O_(2)-induced ferroptosis of 661W cells.These findings indicate solute carrier family 7 member 11 may be a potential therapeutic target for patients with retinal degenerative diseases including age-related macular degeneration.展开更多
文摘对于当前植保无人机喷洒存在重复喷洒、农药残留、缺少在线病虫害检测,且检测方法不易在嵌入式端部署等问题,提出一种植保无人机平台下基于改进YOLOv7的霜霉病与潜叶蝇检测农药喷洒系统。首先,采用渐进金字塔网络AFPN提升模型在特征融合区域的自适应特征融合能力。其次,引入EMA注意力机制模块,利用维度交互的方式来提升融合像素特征。试验结果表明,改进YOLOv7病虫害检测算法的平均精度均值mAP达到94.2%,相比于原始YOLOv7算法提高25.9%,每秒传输帧数FPS相比于原算法提高4.6%。最后,将YOLOv7—AFPN—EMA的病虫害识别模型部署到Jetson Orin Nano上进行验证性检测试验,对比模型改进前后的检测精度。验证结果表明,改进算法相比于原始算法,在线实时检测精度提升11.3%,病虫害检测成功率达89.7%。
基金supported by the National Natural Science Foundation of China,Nos.82171076(to XS)and U22A20311(to XS),82101168(to TL)Shanghai Science and technology Innovation Action Plan,No.23Y11901300(to JS)+1 种基金Science and Technology Commission of Shanghai Municipality,No.21ZR1451500(to TL)Shanghai Pujiang Program,No.22PJ1412200(to BY)。
文摘Progressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss.Ferroptosis has been demonstrated to be associated with retinal degenerative diseases.However,the molecular mechanisms underlying ferroptosis and photoreceptor cell death in age-related macular degeneration remain largely unexplored.Bioinformatics and biochemical analyses in this study revealed xC^(–),solute carrier family 7 member 11-regulated ferroptosis as the predominant pathological process of photoreceptor cell degeneration in a light-induced dry age-related macular degeneration mouse model.This process involves the nuclear factor-erythroid factor 2-related factor 2-solute carrier family 7 member 11-glutathione peroxidase 4 signaling pathway,through which cystine depletion,iron ion accumulation,and enhanced lipid peroxidation ultimately lead to photoreceptor cell death and subsequent visual function impairment.We demonstrated that solute carrier family 7 member 11 overexpression blocked this process by inhibiting oxidative stress in vitro and in vivo.Conversely,solute carrier family 7 member 11 knockdown or the solute carrier family 7 member 11 inhibitor sulfasalazine and ferroptosis-inducing agent erastin aggravated H_(2)O_(2)-induced ferroptosis of 661W cells.These findings indicate solute carrier family 7 member 11 may be a potential therapeutic target for patients with retinal degenerative diseases including age-related macular degeneration.
