Dermatitis is a combination of various skin disease agents such as bacteria,fungi,ectoparasites,viruses and metabolic diseases with various clinical symptoms or signs.Dermatitis can cause an imbalance between ROS and ...Dermatitis is a combination of various skin disease agents such as bacteria,fungi,ectoparasites,viruses and metabolic diseases with various clinical symptoms or signs.Dermatitis can cause an imbalance between ROS and antioxidants.Exogenous antioxidants are needed to help balance antioxidant and ROS levels in the body by providing trigona honey.This study aims to determine the MDA and SOD levels of dogs with complex dermatitis after administration of trigona honey.This study used 12 dogs with complex dermatitis,with a moderate severity score.Dogs 4-6 months old.Samples were divided into control group(P0)without honey,fresh honey group(P1)5 mL/head/day and capsule honey group(P2)0.1 mg/head/day.Honey was given for 4 weeks in the treatment group.Examination of MDA and SOD levels was carried out using the ELISA kit.The results showed that the Trigona honey treatment had a significant effect(P<0.05)in reducing MDA levels and increasing SOD levels in dogs with complex dermatitis.Duncan's test results showed that SOD levels increased significantly at week 4,while week 2 and week 0 did not increase significantly.Trigona honey has anti-inflammatory,antibacterial,antiaging,antiulcer effects,helps in wound healing dermatitis and is an antioxidant.So that trigona honey can reduce plasma MDA levels and increase plasma SOD levels in dogs with complex dermatitis.展开更多
文摘目的:研究尼莫地平联合阿托伐他汀钙对血管性痴呆患者超氧化物歧化酶(Superoxide dismutase,SOD)活性和血脂水平的影响。方法:选择2017年1月~2019年1月我院收治的95例血管性痴呆患者,随机分为两组。对照组口服尼莫地平治疗,每次30 mg,每天3次;观察组在服用尼莫地平的基础上,加服阿托伐他汀钙治疗,每次20 mg,每天1次。比较两组治疗前后的SOD活性和血脂水平。结果:观察组的总有效率高于对照组(P<0.05);治疗后,两组的日常生活能力量表(Activity of daily living scale,ADL)和简易精神状态评价量表(Mini-mental state examination,MMSE)评分均升高(P<0.05),且观察组的高于对照组(P<0.05);治疗后,两组的SOD活性升高(P<0.05),且观察组高于对照组(P<0.05);治疗后,两组的高密度脂蛋白胆固醇(High-density lipoprotein cholesterol,HDL-C)均明显升高(P<0.05),甘油三酯(Triglyceride,TG)、低密度脂蛋白胆固醇(Low-density lipoprotein cholesterol,LDL-C)和总胆固醇(Total Cholesterol,TC)均明显降低(P<0.05),且上述指标的变化程度观察组优于对照组(P<0.05)。结论:尼莫地平联合阿托伐他汀钙能明显提高血管性痴呆患者的SOD活性,改善血脂水平,改善智能认知能力和生活能力。
文摘Dermatitis is a combination of various skin disease agents such as bacteria,fungi,ectoparasites,viruses and metabolic diseases with various clinical symptoms or signs.Dermatitis can cause an imbalance between ROS and antioxidants.Exogenous antioxidants are needed to help balance antioxidant and ROS levels in the body by providing trigona honey.This study aims to determine the MDA and SOD levels of dogs with complex dermatitis after administration of trigona honey.This study used 12 dogs with complex dermatitis,with a moderate severity score.Dogs 4-6 months old.Samples were divided into control group(P0)without honey,fresh honey group(P1)5 mL/head/day and capsule honey group(P2)0.1 mg/head/day.Honey was given for 4 weeks in the treatment group.Examination of MDA and SOD levels was carried out using the ELISA kit.The results showed that the Trigona honey treatment had a significant effect(P<0.05)in reducing MDA levels and increasing SOD levels in dogs with complex dermatitis.Duncan's test results showed that SOD levels increased significantly at week 4,while week 2 and week 0 did not increase significantly.Trigona honey has anti-inflammatory,antibacterial,antiaging,antiulcer effects,helps in wound healing dermatitis and is an antioxidant.So that trigona honey can reduce plasma MDA levels and increase plasma SOD levels in dogs with complex dermatitis.
