The addition of propranolol induced the aggregation of gold nanoparticles,and increased Rayleigh light scattering(RLS)intensity greatly.The interaction between them was studied by RLS spectrum,UV-Vis spectrum and tran...The addition of propranolol induced the aggregation of gold nanoparticles,and increased Rayleigh light scattering(RLS)intensity greatly.The interaction between them was studied by RLS spectrum,UV-Vis spectrum and transmission electron microscopy(TEM).Based on these results,a novel method was proposed for propranolol assay.With the combination of solid phase microextraction(SPME),the proposed method was successfully applied to determine propranolol in urine.展开更多
基金the support from the National Natural Science Foundation of China(No.20275028)973 Program(No.2002CB2118)863 Program(No.2002AA2Z2004).
文摘The addition of propranolol induced the aggregation of gold nanoparticles,and increased Rayleigh light scattering(RLS)intensity greatly.The interaction between them was studied by RLS spectrum,UV-Vis spectrum and transmission electron microscopy(TEM).Based on these results,a novel method was proposed for propranolol assay.With the combination of solid phase microextraction(SPME),the proposed method was successfully applied to determine propranolol in urine.
