期刊文献+
共找到63,302篇文章
< 1 2 250 >
每页显示 20 50 100
The intelligent leap of wireless short-range connection
1
作者 Wan Lei 《China Standardization》 2026年第1期47-47,共1页
Founded in September 2020,the International SparkLink Alliance(iSLA)now has approximately 1,200 members in diverse sectors including terminals,homes,vehicles,manufacturing,transportation,finance and healthcare.The iSL... Founded in September 2020,the International SparkLink Alliance(iSLA)now has approximately 1,200 members in diverse sectors including terminals,homes,vehicles,manufacturing,transportation,finance and healthcare.The iSLA has established a technical standards system for wireless short-range communication covering full-stack standards such as the end-to-end protocol system. 展开更多
关键词 wireless short range communication end end protocol system technical standards system full stack standards international sparklink alliance isla now wireless short range connection standards system ISLA
原文传递
Short bouts of accumulated exercise:Review and consensus statement on definition,efficacy,feasibility,practical applications,and future directions 被引量:1
2
作者 Mingyue Yin Yongming Li +43 位作者 Abdul Rashid Aziz Aidan Buffey David J.Bishop Dapeng Bao George P.Nassis Hashim Islam Hongying Wang Jackson J.Fyfe Jianfang Xu Jianxiu Liu Jiexiu Zhao Jingwei Cao Jonathan P.Little Junqiang Qiu Keith M.Diaz Lijuan Wang Liye Zou Max J.Western Meynard L.Toledo Min Hu Minghui Quan Neville Owen Niels B.J.Vollaard Olivier Girard Qingde Shi Richard S.Metcalfe Rodrigo Ramirez-Campillo Ru Wang Waris Wongpipit Weimo Zhu Wenfei Zhu Weigang Xu Xiaochun Wang Xiaoping Chen Xiong Wang Xu Wen Yang Liu Ying Gao Yue Fu Zhaowei Kong Zhenbo Cao Zhengzhen Wang Peijie Chen Lijuan Mao 《Journal of Sport and Health Science》 2026年第2期1-30,共30页
Background:Insufficient physical activity and prolonged sedentary behavior have emerged as major global public health challenges.Short bouts(≤10 min)of accumulated exercise(SBAE)throughout the day may be a promising ... Background:Insufficient physical activity and prolonged sedentary behavior have emerged as major global public health challenges.Short bouts(≤10 min)of accumulated exercise(SBAE)throughout the day may be a promising strategy to mitigate the adverse effects of prolonged sitting and promote physical activity,ultimately promoting overall health.However,previous ambiguity in defining this concept has resulted in a fragmented and inconsistent evidence base,impeding practical applications,the development of guidelines,and policymaking.The purpose of this study is to establish an operational definition of SBAE by synthesizing systematic reviews and research trials alongside an expert consensus.Additionally,it seeks to evaluate acute and long-term efficacy and feasibility,providing evidence-based recommendations for practice and future research directions.Methods:A literature search was performed across PubMed and Web of Science,followed by systematic screening and summarization of eligible studies based on predefined inclusion criteria.Inclusion criteria encompassed various modes/types of SBAE(bouts lasting≤10 min,performed multiple times daily with≥30 min intervals);both aerobic and resistance exercise were considered.Relevant systematic reviews and research trials were included.Methodological quality,risk of bias,and evidence certainty were assessed.Expert consensus was obtained through a survey to evaluate recommendations and agreement levels on findings.Results:After analyzing 27 systematic reviews,135 research studies,and an expert consensus involving 48 researchers from 11 countries,SBAE is defined as any exercise mode of activity,regardless of intensity,that is accumulated in either continuous or intermittent bouts lasting≤10 min per session(including multiple intermittent sets)that are performed multiple times(≥2 sessions/day)per day,with intervals of≥30 min between bouts or otherwise sufficient time for recovery.When used to interrupt prolonged periods of sedentary time,SBAE mitigates the acute adverse effects of sedentary behavior on more than 10 clinical biomarkers of endocrine,cardiovascular,and brain health/function among adults of diverse ages and conditions.Moreover,SBAE was superior for improving acute glycemic control compared to a single continuous exercise session.As a long-term intervention(average of 11 weeks),SBAE can improve over 20 health outcomes,including peak oxygen uptake,resting blood pressure,and metabolic health.Additionally,SBAE might be more effective than continuous exercise for improving longer-term glycemic control and body composition.Long-term completion rates for SBAE interventions are generally high(95%),with low dropout rates(12%)and high adherence rates even without supervision(85%),and its safety has been preliminarily validated.Conclusion:An operational definition of SBAE is provided along with its classification and acute and long-term efficacy.Practical exercise prescription recommendations and evidence-based strategies for various populations and contexts are provided.Future research should focus on generating high-quality evidence for SBAE in 5 key areas:quantification and monitoring,population-specific responses,optimization of exercise prescriptions,intervention efficacy,and practical implementation.Additionally,addressing policy,environmental,and promotional barriers is crucial for transitioning from expert consensus to public consensus,and for facilitating the application of this strategy in real-world environments. 展开更多
关键词 short bouts of accumulated exercise Exercise snacks Consensus statement Sedentary breaks
在线阅读 下载PDF
Short-chain fatty acids mediate enteric and central nervous system homeostasis in Parkinson’s disease:Innovative therapies and their translation 被引量:1
3
作者 Shimin Pang Zhili Ren +1 位作者 Hui Ding Piu Chan 《Neural Regeneration Research》 2026年第3期938-956,共19页
Short-chain fatty acids,metabolites produced by the fermentation of dietary fiber by gut microbiota,have garnered significant attention due to their correlation with neurodegenerative diseases,particularly Parkinson’... Short-chain fatty acids,metabolites produced by the fermentation of dietary fiber by gut microbiota,have garnered significant attention due to their correlation with neurodegenerative diseases,particularly Parkinson’s disease.In this review,we summarize the changes in short-chain fatty acid levels and the abundance of short-chain fatty acid-producing bacteria in various samples from patients with Parkinson’s disease,highlighting the critical role of gut homeostasis imbalance in the pathogenesis and progression of the disease.Focusing on the nervous system,we discuss the molecular mechanisms by which short-chain fatty acids influence the homeostasis of both the enteric nervous system and the central nervous system.We identify key processes,including the activation of G protein-coupled receptors and the inhibition of histone deacetylases by short-chain fatty acids.Importantly,structural or functional disruptions in the enteric nervous system mediated by these fatty acids may lead to abnormalα-synuclein expression and gastrointestinal dysmotility,which could serve as an initiating event in Parkinson’s disease.Furthermore,we propose that short-chain fatty acids help establish communication between the enteric nervous system and the central nervous system via the vagal nerve,immune circulation,and endocrine signaling.This communication may shed light on their potential role in the transmission ofα-synuclein from the gut to the brain.Finally,we elucidate novel treatment strategies for Parkinson’s disease that target short-chain fatty acids and examine the challenges associated with translating short-chain fatty acid-based therapies into clinical practice.In conclusion,this review emphasizes the pivotal role of short-chain fatty acids in regulating gut-brain axis integrity and their significance in the pathogenesis of Parkinson’s disease from the perspective of the nervous system.Moreover,it highlights the potential value of short-chain fatty acids in early intervention for Parkinson’s disease.Future research into the molecular mechanisms of short-chain fatty acids and their synergistic interactions with other gut metabolites is likely to advance the clinical translation of innovative short-chain fatty acid-based therapies for Parkinson’s disease. 展开更多
关键词 ALPHA-SYNUCLEIN blood-brain barrier blood circulation central nervous system ENDOCRINE enteric nervous system glial cell gut-brain axis gut microbiota intestinal barrier neuron Parkinson’s disease short chain fatty acids vagus nerve
暂未订购
The Relationship between Parental Marital Conflict and Adolescent Short Video Dependence:A Chain Mediation Model
4
作者 Lei Yang Yang Liu 《International Journal of Mental Health Promotion》 2026年第1期168-186,共19页
Background:This study aims to investigate the underlying mechanisms between parental marital conflict and adolescent short video dependence by constructing a chain mediation model,focusing on the mediating roles of ex... Background:This study aims to investigate the underlying mechanisms between parental marital conflict and adolescent short video dependence by constructing a chain mediation model,focusing on the mediating roles of experiential avoidance and emotional disturbance(anxiety,depression,and stress).Methods:Conducted in January 2025,the research recruited 4125 adolescents from multiple Chinese provinces through convenience sampling;after data cleaning,3957 valid participants(1959 males,1998 females)were included.Using a cross-sectional design,measures included parental marital conflict,experiential avoidance,anxiety,depression,stress,and short video dependence.Results:Pearson correlation analysis revealed significant positive correlations among all variables.Mediation analysis using the SPSS PROCESS macro showed that parental marital conflict directly predicted short video dependence(β=0.269,p<0.001),and also significantly predicted experiential avoidance(β=0.519,p<0.001),anxiety(β=0.072,p<0.001),depression(β=0.067,p<0.001),and stress(β=0.048,p<0.05).Experiential avoidance further predicted anxiety(β=0.521,p<0.001),depression(β=0.489,p<0.001),stress(β=0.408,p<0.001),and short video dependence(β=0.244,p<0.001).While both anxiety(β=0.050,p<0.05)and depression(β=0.116,p<0.001)positively predicted short video dependence,stress did not(β=0.019,p=0.257).Overall,experiential avoidance,anxiety,depression,and stress significantly mediated the relationship between parental marital conflict and short video dependence.Conclusion:These findings confirm that parental marital conflict not only directly influences adolescent short video dependence but also operates through a chain mediation pathway involving experiential avoidance and emotional disturbance,highlighting central psychological mechanisms and providing theoretical support for integrated mental health and behavioral interventions. 展开更多
关键词 Parental marital conflict experiential avoidance ANXIETY depression stress emotional disturbance short video dependence
暂未订购
The Connection Paradox:How Social Support Facilitates Short Video Addiction and SolitaryWell-Being among Older Adults in China
5
作者 Yue Cui Ziqing Yang Hao Gao 《International Journal of Mental Health Promotion》 2026年第1期108-122,共15页
Background:In the Chinese context,the impact of short video applications on the psychological well-being of older adults is contested.While often examined through a pathological lens of addiction,this perspective may ... Background:In the Chinese context,the impact of short video applications on the psychological well-being of older adults is contested.While often examined through a pathological lens of addiction,this perspective may overlook paradoxical,context-dependent positive outcomes.Therefore,the main objective of this study is to challenge the traditional Compensatory Internet Use Theory by proposing and testing a chained mediation model that explores a paradoxical pathway from social support to life satisfaction via problematic social media use.Methods:Data were collected between July and August 2025 via the Credamo online survey platform,yielding 384 valid responses from Chinese older adults aged 60 and above.Key constructs were assessed using the Social Support Rating Scale(SSRS),Bergen Social Media Addiction Scale(BSMAS),Simplified UCLA Loneliness Scale,and Satisfaction with Life Scale(SWLS).A chained mediation model was tested using stepwise regression and non-parametric bootstrapping(5000 resamples),controlling for age,gender,household income,and health status.Results:The analysis revealed a paradoxical pathway,which was clarified by a key statistical suppression effect.Social support significantly and positively predicted problematic usage(β=0.157,p=0.002).After controlling for the suppressor effect of social support,problematic usage in turn negatively predicted social connectedness(β=−0.177,p<0.001).Finally,reduced social connectedness—reflecting a state of solitude—positively predicted life satisfaction(β=−0.227,p<0.001).Conclusion:The findings suggest that for older adults with sufficient offline social support,these resources may serve a“social empowerment”function.This empowerment allows behaviors measured as“problematic usage”to be theoretically reframed as a form of“deep immersive entertainment”.This immersion appears to occur alongside a state of“high-quality solitude”,which ultimately is associated with higher life satisfaction.This study provides a novel,non-pathological theoretical perspective on the consequences of high engagement with emerging social media,offering empirical grounds for non-abstinence-based intervention strategies. 展开更多
关键词 short video addiction social support social connectedness life satisfaction older adults in China chained mediation high-quality solitude
在线阅读 下载PDF
Demonstration of full-scale spatiotemporal diagnostics of solid-density plasmas driven by an ultra-short relativistic laser pulse using an X-ray free-electron laser
6
作者 Lingen Huang Michal Smíd +42 位作者 Long Yang Oliver Humphries Johannes Hagemann Thea Engler Xiayun Pan Yangzhe Cui Thomas Kluge Ritz Aguilar Carsten Baehtz Erik Brambrink Engin Eren Katerina Falk Alejandro Laso Garcia Sebastian Gode Christian Gutt Mohamed Hassan Philipp Heuser Hauke Hoppner Michaela Kozlova Wei Lu Josefine Metzkes-Ng Masruri Masruri Mikhail Mishchenko Motoaki Nakatsutsumi Masato Ota Ozgül Oztürk Alexander Pelka Irene Prencipe Thomas R.Preston Lisa Randolph Martin Rehwald Hans-Peter Schlenvoigt Ulrich Schramm Jan-Patrick Schwinkendorf Sebastian Starke Radka Stefaníková Erik Thiessenhusen Monika Toncian Toma Toncian Jan Vorberger Ulf Zastrau Karl Zeil Thomas E.Cowan 《Matter and Radiation at Extremes》 2026年第1期6-19,共14页
Understanding the complex plasma dynamics in ultra-intense relativistic laser-solid interactions is of fundamental importance for applications of laser-plasma-based particle accelerators,the creation of high-energy-de... Understanding the complex plasma dynamics in ultra-intense relativistic laser-solid interactions is of fundamental importance for applications of laser-plasma-based particle accelerators,the creation of high-energy-density matter,understanding planetary science,and laser-driven fusion energy.However,experimental efforts in this regime have been limited by the lack of accessibility of over-critical densities and the poor spatiotemporal resolution of conventional diagnostics.Over the last decade,the advent of femtosecond brilliant hard X-ray free-electron lasers(XFELs)has opened new horizons to overcome these limitations.Here,for the first time,we present full-scale spatiotemporal measurements of solid-density plasma dynamics,including preplasma generation with tens of nanometer scale length driven by the leading edge of a relativistic laser pulse,ultrafast heating and ionization at the main pulse arrival,the laser-driven blast wave,and transient surface return current-induced compression dynamics up to hundreds of picoseconds after interaction.These observations are enabled by utilizing a novel combination of advanced X-ray diagnostics including small-angle X-ray scattering,resonant X-ray emission spectroscopy,and propagation-based X-ray phase-contrast imaging simultaneously at the European XFEL-HED beamline station. 展开更多
关键词 preplasma generation spatiotemporal diagnostics understanding complex plasma dynamics x ray free electron laser planetary scienceand conventional diagnosticsover solid density plasmas ultra short relativistic laser pulse
在线阅读 下载PDF
1例SHORT综合征胎儿的遗传学分析
7
作者 彭园园 侯晓琳 +3 位作者 李娜 闫利伟 陈艳东 于湄 《现代妇产科进展》 2025年第7期559-560,共2页
SHORT综合征(OMIM 269880)是一种罕见的常染色体显性遗传性疾病,由Gorlin等[1]于1975年首次报道并命名。SHORT是一个首字母缩略词,强调了首次描述的最显著的临床特征:身材矮小(S)、超延展性(H)、眼部凹陷(O)、Rieger异常(R)和出牙延迟(T... SHORT综合征(OMIM 269880)是一种罕见的常染色体显性遗传性疾病,由Gorlin等[1]于1975年首次报道并命名。SHORT是一个首字母缩略词,强调了首次描述的最显著的临床特征:身材矮小(S)、超延展性(H)、眼部凹陷(O)、Rieger异常(R)和出牙延迟(T)。随后关于SHORT综合征患者的报告进一步拓宽了该病的临床表型,包括胎儿宫内生长受限、脂肪萎缩、面部畸形、胰岛素抵抗、听力损失等[2]。目前已有的文献报道SHORT综合征患者尚不足百例。我国已报道14例,患者年龄从生后2d至23岁不等[3-4]。本研究报道了1例产前超声表现为严重宫内生长受限的SHORT综合征胎儿,以提高临床医师对该综合征的认识和产前诊断意识。 展开更多
关键词 short综合征 PIK3R1基因 宫内生长受限 c.1456G>A变异
暂未订购
Potential Effect of Short Video Usage Intensity on Short Video Addiction, Perceived Mood Enhancement (‘TikTok Brain’), and Attention Control among Chinese Adolescents
8
作者 Jian-Hong Ye Junpeng Zheng +1 位作者 Weiguaju Nong Xiantong Yang 《International Journal of Mental Health Promotion》 2025年第3期271-286,共16页
Objectives:Short video addiction has emerged as a significant public health issue in recent years,with a growing trend toward severity.However,research on the causes and impacts of short video addiction remains limite... Objectives:Short video addiction has emerged as a significant public health issue in recent years,with a growing trend toward severity.However,research on the causes and impacts of short video addiction remains limited,and understanding of the variable“TikTok brain”is still in its infancy.Therefore,based on the Stimulus-Organism-Behavior-Consequence(SOBC)framework,we proposed six research hypotheses and constructed a model to explore the relationships between short video usage intensity,TikTok brain,short video addiction,and decreased attention control.Methods:Given that students are considered a high-risk group for excessive short video use,we collected 1086 valid participants from Chinese student users,including 609 males(56.1%)and 477 females(43.9%),with an average participant age of 19.84 years,to test the hypotheses.Results:(1)Short video usage intensity was positively related to short video addiction,TikTok brain,and decreased attention control;(2)TikTok brain was positively related to short video addiction and decreased attention control;and(3)Short video addiction was positively related to decreased attention control.Conclusions:These findings suggest that although excessive use of short video applications brings negative consequences,users still spend significant amounts of time on these platforms,indicating a need for strict self-regulation of usage time. 展开更多
关键词 Decreased attention control short video addiction excessive short video use stimulus-organism-behavior-consequence(SOBC)framework TikTok addiction TikTok brain
在线阅读 下载PDF
Long-term follow-up result of short metaphyseal femoral stem in primary total hip arthroplasty:A retrospective study
9
作者 Manoj Kumar Ayush Sharma +2 位作者 Vivek P Ksheerasagar Akash K Ghosh Mukund Lal 《World Journal of Orthopedics》 2025年第1期40-45,共6页
BACKGROUND Total hip arthroplasty(THA)has increased along with an increasing demand for improved quality of life.Combined with prolonged life expectancy,the number of revision surgeries is expected to increase.Stress ... BACKGROUND Total hip arthroplasty(THA)has increased along with an increasing demand for improved quality of life.Combined with prolonged life expectancy,the number of revision surgeries is expected to increase.Stress shielding is a significant issue with traditional femoral stems used in THA,making revision surgeries particularly challenging in younger patients.This has sparked renewed interest in studying safety and functional outcomes of short metaphyseal femoral stems,which have the potential to alleviate these challenges and simplify revision surgeries.AIM To evaluate the long-term outcomes of short-stem THA.METHODS A total of 124 hips that underwent THA using the short femoral stem(TRILOCK®Depuy)between May 2006 and November 2008 were included in this study.Patients were followed for a period of 15 years.Outcomes were assessed in terms of pain relief,hip joint range of motion,improvement in mobility,and functional outcomes using the modified Harris Hip Score,Oxford hip score,and Western Ontario and McMaster Universities Osteoarthritis index score.RESULTS A total of 124 hips in 98 patients were evaluated.Significant improvements in functional outcomes were observed over the 15-year follow-up period,with no cases of subsidence,implant loosening,or complications necessitating revision surgery.The only complication reported was heterotopic ossification in 1 patient.CONCLUSION Short metaphyseal stems provide better functional outcomes with early mobilization,and its long-term follow-up without subsidence,implant loosening,or proximal femoral bone loss simplifies revision surgery in younger patients. 展开更多
关键词 short stem total hip replacement short metaphyseal stem Uncemented hip replacement Proximal femur osteolysis Proximal femur bone loss
暂未订购
Laser-implanted short fiber-like interface structure for strengthening welde d-braze d joint of Al/steel dissimilar metals 被引量:1
10
作者 Lize Li Jianyu Li +4 位作者 Shuhai Chen Shujun Chen Jian Yang Jihua Huang Gaoyang Yu 《Journal of Materials Science & Technology》 2025年第34期68-82,共15页
The lamellar layer of intermetallic compounds(IMCs)was adversely affected the performance of welding-brazing joints in Al/steel dissimilar metals.In this study,a short fiber-like surface morphology was fabricated on t... The lamellar layer of intermetallic compounds(IMCs)was adversely affected the performance of welding-brazing joints in Al/steel dissimilar metals.In this study,a short fiber-like surface morphology was fabricated on the butt surface of Q235 steel via laser.The interaction behavior between the short fibers and the molten pool was captured using a high-speed camera.Laser-arc hybrid welding-brazing was then employed to join Al(6061-T6)to the steel.This process successfully created a short fiber-like interface structure at the joint.The relationship between microstructure and mechanical properties was investigated,compared with Al/bare steel(ABS)joint.The research results indicated that the IMCs layer consisted of FeAl_(3)and Fe_(2)Al_(5).The interface strength of the Al/short fiber-like surface structural steel(ASFSSS)joint reached 153.2 MPa,an 82.2%increase compared to the ABS joint,which reached 84.1 MPa.When the ASFSSS joints without the reinforcement were bent to 58.2°and 25.2°in the longitudinal and transverse direction,respectively,they remained intact.However,cracks were discovered when the bending angle of the ABS reached 39.1°and 0°in the two directions.Numerical simulation revealed that the short fiber-like interface structure significantly reduced residual stress and improved the stress distribution in the weld,thereby enhancing the strength and toughness of Al/steel dissimilar joints.The crack propagation path in the ASFSSS joint was deflected into the weld when it encountered short fibers,and the fracture morphology presented the characteristic of ductile-brittle mixed fracture. 展开更多
关键词 short fiber-like interface structure Laser-arc welding-brazing Al/steel dissimilar joint Intermetallic compounds Mechanical properties
原文传递
Research Status of Short Process Forming Techniques for Brazing and Soldering Materials
11
作者 Dong Bowen Shi Guangyuan +4 位作者 Zhong Sujuan Dong Xian Cheng Yafang Long Weimin Zhang Guanxing 《稀有金属材料与工程》 北大核心 2025年第2期377-384,共8页
Short process forming techniques for brazing and soldering materials can shorten the process,improve product quality,and increase production efficiency,which has received much attention from welding researchers.This r... Short process forming techniques for brazing and soldering materials can shorten the process,improve product quality,and increase production efficiency,which has received much attention from welding researchers.This review mainly summarized the research reports on short process forming techniques for brazing and soldering materials.Firstly,the traditional process and its shortcomings were presented.Secondly,the latest research of short process forming technologies,such as continuous casting technique,atomization powder technique,solder ball forming technique,and rapid solidification technique,was summarized,and the traditional forming performance of several brazing and soldering materials was introduced.Finally,the current restrictions and research trends of short process forming technique for brazing and solder materials were put forward,providing theoretical guidance and reference for related research and technique development in brazing and soldering field. 展开更多
关键词 short process forming technique continuous casting atomization powder soldering ball rapid solidification amorphous filler metals
原文传递
Genome-wide profiling of polymorphic short tandem repeats and their influence on gene expression and trait variation in diverse rice populations
12
作者 Xiyu Tan Wanyong Zeng +7 位作者 Yujian Yang Zhansheng Lin Fuquan Li Jianhong Liu Shaotong Chen Yao-Guang Liu Weibo Xie Xianrong Xie 《Journal of Genetics and Genomics》 2025年第6期733-746,共14页
Short tandem repeats(STRs)modulate gene expression and contribute to trait variation.However,a systematic evaluation of the genomic characteristics of STRs has not been conducted,and their influence on gene expression... Short tandem repeats(STRs)modulate gene expression and contribute to trait variation.However,a systematic evaluation of the genomic characteristics of STRs has not been conducted,and their influence on gene expression in rice remains unclear.Here,we construct a map of 137,629 polymorphic STRs in the rice(Oryza sativa L.)genome using a population-scale resequencing dataset.A genome-wide survey encompassing 4726 accessions shows that the occurrence frequency,mutational patterns,chromosomal distribution,and functional properties of STRs are correlated with the sequences and lengths of repeat motifs.Leveraging a transcriptome dataset from 127 rice accessions,we identify 44,672 expression STRs(eSTRs)by modeling gene expression in response to the length variation of STRs.These eSTRs are notably enriched in the regulatory regions of genes with active transcriptional signatures.Population analysis identifies numerous STRs that have undergone genetic divergence among different rice groups and 1726 tagged STRs that may be associated with agronomic traits.By editing the(ACT)_(7) STR in OsFD1 promoter,we further experimentally validate its role in regulating gene expression and phenotype.Our study highlights the contribution of STRs to transcriptional regulation in plants and establishes the foundation for their potential use as alternative targets for genetic improvement. 展开更多
关键词 Gene expression Genomic variation Rice short tandem repeat STR Transcriptional regulation
原文传递
Real-world effectiveness and safety of teduglutide in adult and pediatric patients with short bowel syndrome in Argentina
13
作者 Héctor Solar Muñiz Adriana Fernández +17 位作者 Verónica Busoni María Inés Martínez Carolina Rumbo Silvia De Barrio Carola Saure Martín Balacco Martín Gonzalo Buncuga Corina Dlugoszweski Alejandra Manzur Lorena Rudi María Dolores Matoso Sandra Cosentino Federico Ussher Fernando Manzur Julia Demarchi Elisa Malaver Laura Brion Laura Ungar 《World Journal of Gastrointestinal Pharmacology and Therapeutics》 2025年第4期143-155,共13页
BACKGROUND Approval of teduglutide is an important addition to the limited treatment options for short bowel syndrome(SBS).However,real-world evidence on teduglutide therapy for SBS in Latin America is scarce.AIM To i... BACKGROUND Approval of teduglutide is an important addition to the limited treatment options for short bowel syndrome(SBS).However,real-world evidence on teduglutide therapy for SBS in Latin America is scarce.AIM To investigate the effectiveness and safety of teduglutide in clinical practice in Argentina with a 24-week follow-up.METHODS This non-interventional multicentre cohort study included consecutive patients(aged≥1 years)with SBS who were dependent on parenteral support(PS)and received≥1 dose of teduglutide according to currently approved indications.RESULTS The study population(n=45)included 21 adult and 24 pediatric patients.The proportion of adult and pediatric patients who showed clinical response(defined as a≥20%reduction in weekly PS volume)after 24 weeks of treatment was 90.4%[95%confidence interval(CI):69.6%-98.8%]and 83.3%(95%CI:62.6%-95.2%),respectively.Overall,12 patients(26.6%;95%CI:14.6-41.9)were weaned from PS support at the 24-week assessment,6(28.5%;95%CI:11.5-52.1)in the adult cohort,and 6(25%;95%CI:9.7-46.7)in the pediatric cohort.Only baseline PS requirement was inversely associated with weaning from PS(P=0.025).The most frequently reported treatmentemergent adverse events(TEAEs)were mild to moderate abdominal pain and abdominal distension(16.6%;and 9.5%,respectively).None of the reported TEAEs led to treatment discontinuation.CONCLUSION This prospective real-world study demonstrated the effectiveness and safety of teduglutide in adult and pediatric patients with SBS in Argentina.The clinical response observed in both adults and pediatric patients was greater than that reported in phase 3 trials and was consistent with the results of other real-world studies. 展开更多
关键词 short bowel syndrome Intestinal failure Parenteral nutrition Parenteral support WEANING Teduglutide Realworld
暂未订购
A Study on the Theme Orientation and Emotional Identity of Metaphorical Network Hot Words in Short Videos
14
作者 ZHANG Wei-jie 《Journal of Literature and Art Studies》 2025年第4期310-316,共7页
In the wave of internet culture,short videos have become an indispensable medium for social communication.The metaphorical hot words contained within them serve as a unique linguistic phenomenon that leads topics and ... In the wave of internet culture,short videos have become an indispensable medium for social communication.The metaphorical hot words contained within them serve as a unique linguistic phenomenon that leads topics and focuses attention,greatly enriching the expressive layers and rhetorical charm of short videos,and significantly enhancing the video’s theme orientation and emotional identification.This research aims to explore the relationship between the use of metaphorical Internet buzzwords in short videos and the thematic and emotional orientation.The study adopts a combination of qualitative and quantitative methods,taking 10 videos with over 10,000 likes posted by a well-known blogger on Xiaohongshu in 2024 as the research object,transcribing the text,forming research corpora,and conducting multi-dimensional cognitive analysis on them.The study shows that about half of short videos contain metaphorical hot words.Different types of metaphorical hot words can trigger different emotional reactions from fans,especially humorous metaphorical hot words that can stimulate fans’emotional identification and resonance.In addition,in terms of fan participation,videos using metaphorical hot words tend to attract more fan attention than those that do not:these videos not only attract more fans to watch and like,but also trigger more comments and sharing behaviors.In summary,short videos cleverly use metaphors to create internet hot words,significantly enhancing the video’s thematic guidance and emotional resonance,manifested in creating popular topics,clarifying guiding themes,enhancing content attractiveness,and stimulating strong emotional identification,thereby promoting interactive behaviors such as likes and shares.These findings provide a reference for research in related fields such as metaphor,communication studies,and sociology. 展开更多
关键词 short videos internet hot words metaphor theme orientation emotional identity
在线阅读 下载PDF
Machine Learning Approach for Short- and Long-Term Global Solar Irradiance Prediction
15
作者 Oliver O.Apeh Nnamdi I.Nwulu 《Journal of Environmental & Earth Sciences》 2025年第1期321-342,共22页
Solar radiation data forecasting algorithms are important,especially in developing countries,as vast solar power plants cannot measure reliable and constant solar irradiance.The challenges of solar irradiance predicti... Solar radiation data forecasting algorithms are important,especially in developing countries,as vast solar power plants cannot measure reliable and constant solar irradiance.The challenges of solar irradiance prediction may be resolved by machine learning using weather datasets.This study emphasises the daily and monthly global solar radiation data predictions of three locations,Pretoria,Bloemfontein,and Vuwani,at different provinces in South Africa with various solar radiation distributions.The study evaluated five different machine learning models.Forecasting models were established to evaluate global solar radiation,focusing on input data.The selected forecast models are centered on their ability to perform with time series data.These models use five years of data from meteorological parameters,such as global horizontal irradiance(GHI),relative humidity,wind speed and ambient temperature between 1 January 2018 and 31 December 2022.The datasets from these meteorological parameters are utilised for training and testing the employed algorithms,which are examined using five statistical metrics.Moreover,the inconsistency of the solar irradiance time series was equally assessed using the clearness index.The results from this study demonstrate that the R2 value recording 0.866 datasets in Bloemfontein of random forest algorithm presents the highest performance during the training processes for all models studied,while the random tree in Vuwani showed the lowest performance of R2 of 0.210 with other algorithms in testing processes.Additionally,the maximum solar radiation was found in December for both Pretoria and Bloemfontein,recorded as 5.347 and 5.844 kWh/m2/day,respectively,while it was 4.692 kWh/m2/day at Vuwani in January.Similarly,the average clearness index of 0.605,0.657 and 0.533 are obtained at Pretoria,Bloemfontein,and Vuwani,respectively.Among the three sites under study,the solar radiation and clearness index are higher in Bloemfontein.Therefore,the proposed algorithms could be used conveniently for short-and long-term solar power plants in South Africa. 展开更多
关键词 Machine Learning Solar Radiation short and Long-Term Forecasting Statistical Metrics
在线阅读 下载PDF
Impact of teduglutide on pediatric short bowel syndrome:A systematic review and trial sequential meta-analysis
16
作者 Pan Jiao Zhong-Jing Zhang +5 位作者 Ying Jiang Jun Zhou Ke-Heng Deng Wen-Xiang Zhu Xiang-You Zhao Zhao-Kun Guo 《World Journal of Gastrointestinal Surgery》 2025年第12期423-431,共9页
BACKGROUND Pediatric short bowel syndrome(SBS)poses management challenges,and teduglutide is a potential therapy.However,comprehensive data on its pediatric safety are lacking.AIM To evaluate the impact of teduglutide... BACKGROUND Pediatric short bowel syndrome(SBS)poses management challenges,and teduglutide is a potential therapy.However,comprehensive data on its pediatric safety are lacking.AIM To evaluate the impact of teduglutide on infection and gastrointestinal adverse events in pediatric SBS patients via systematic review and meta-analysis.METHODS Following PRISMA 2009 guidelines and PROSPERO registration,we searched PubMed,Web of Science,and EMBASE for randomized controlled trials(RCTs)(pediatric SBS patients≤18 years;teduglutide vs placebo/standard care).Two reviewers screened studies,extracted data,and assessed bias(ROB2).Metaanalyses used RevMan 5.4(Mantel-Haenszel method,random-effects if I^(2)≠0).Trial sequential analysis and GRADE were applied.RESULTS Three RCTs involving 115 pediatric patients were included.Pooled analysis revealed no statistically significant differences between the teduglutide and control groups for the primary outcome of infection events[RR=0.83;(95%CI:0.44-1.56);P=0.57;I^(2)=0%;2 studies,n=55].Similarly,no significant differences were found for secondary outcomes:Upper respiratory tract infection[RR=0.68;(95%CI:0.32-1.47);P=0.33;I^(2)=0%],catheter site infection[RR=1.86;(95%CI:0.23-14.78);P=0.56;I^(2)=0%],vomiting[RR=1.35;(95%CI:0.10-18.23);P=0.82;I^(2)=72%],abdominal pain[RR=2.47;(95%CI:0.50-12.16);P=0.27;I^(2)=0%],nausea[RR=1.31;(95%CI:0.24-7.22);P=0.75;I^(2)=0%],diarrhea[RR=1.02;(95%CI:0.23-4.43);P=0.98;I^(2)=0%],and abdominal distension[RR=1.49;(95%CI:0.18-12.35);P=0.71;I^(2)=0%].The overall certainty of evidence assessed by GRADE was moderate.CONCLUSION Teduglutide does not increase infection or gastrointestinal adverse event risk in pediatric SBS,but small sample sizes limit conclusions.Larger studies are needed. 展开更多
关键词 Teduglutide Pediatric short bowel syndrome Systematic review META-ANALYSIS Trial sequential analysis Safety profile
暂未订购
Short Videos
17
作者 YAO QIUXIN GETAHUN ASSEFA TESSEMA 《ChinAfrica》 2025年第11期60-61,共2页
The Double Take column looks at a single topic from an African and Chinese perspective.This month,we explore how we can cope with the influence of short videos.
关键词 coping strategies African perspective Chinese perspective short videos
原文传递
Inferior epigastric artery cuff interposition for short renal artery in living-donor kidney transplantation:A case report and review of literature
18
作者 Brahim Lekehal Noura Ait Youssef +3 位作者 Mehdi Lekehal Tarik Bakkali Asma Jdar Ayoub Bounssir 《World Journal of Transplantation》 2025年第4期489-496,共8页
BACKGROUND Kidney transplantation is increasingly more common due to the ongoing shortage of deceased donors.However,anatomical challenges,such as a short renal artery,can complicate surgical procedures and increase c... BACKGROUND Kidney transplantation is increasingly more common due to the ongoing shortage of deceased donors.However,anatomical challenges,such as a short renal artery,can complicate surgical procedures and increase complication risk,including thrombosis and anastomotic stenosis.To address these issues and optimize graft outcomes,innovative surgical techniques are essential.CASE SUMMARY We present a case of kidney transplantation complicated by a short donor renal artery.To address the discrepancy between arterial length and diameter mismatch,the recipient’s inferior epigastric artery was used as a cuff interposition for arterial reconstruction.Following standard laparoscopic donor nephrectomy,vascular reconstruction was performed on the back table.The use of the inferior epigastric artery as a cuff allowed for successful elongation and size matching of the donor renal artery,enabling a tension-free anastomosis to the recipient’s external iliac artery.Postoperative Doppler ultrasound and angiography confirmed excellent graft perfusion.The patient experienced an uneventful recovery with immediate graft function and maintained stable renal function at 6 months post-transplant.To our knowledge,this is the first reported use of the inferior epigastric artery as a cuff interposition in renal artery reconstruction,offering a novel and effective technique for managing short renal arteries in kidney transplantation.CONCLUSION Interposition of the epigastric artery offers an innovative technique for managing short donor renal arteries,reducing the risk of early thrombosis and long-term complications as size mismatch and intimal hyperplasia. 展开更多
关键词 Inferior epigastric artery Cuff interposition short renal artery Living kidney donor TRANSPLANTATION Case report
暂未订购
Application of Short Videos in Agricultural Scenarios and Basic Production Techniques
19
作者 Jinfa HE Jiancheng DING +3 位作者 Peiqin WANG Lianwei SHAN Lijuan ZHANG Zichen LYU 《Agricultural Biotechnology》 2025年第5期81-85,共5页
The application of short videos in agricultural scenarios has become a new form of productive force driving agricultural development,injecting new vitality and opportunities into traditional agriculture.These videos l... The application of short videos in agricultural scenarios has become a new form of productive force driving agricultural development,injecting new vitality and opportunities into traditional agriculture.These videos leverage the unique expressive logic of the platform by adopting a small entry point and prioritizing dissemination rate.They are strategically planned in terms of content,visuals,and interaction to cater to users needs for relaxation,knowledge acquisition,social sharing,agricultural product marketing,and talent display.Through careful design,full creativity,rich emotion,and the creation of distinct character personalities,these videos deliver positive,entertaining,informative,and opinion-driven agricultural content.The production and operation of agricultural short videos can be effectively optimized by analyzing the characteristics of both popular and less popular videos,and utilizing smart tools and trending topics. 展开更多
关键词 short video Small entry point Dissemination rate Three-second law Popular video
在线阅读 下载PDF
Research on the International Communication Path of Intangible Cultural Heritage Short Videos of the Beijing-Hangzhou Grand Canal
20
作者 QI Gang 《Journalism and Mass Communication》 2025年第5期284-290,共7页
As a World Cultural Heritage site,the Beijing-Hangzhou Grand Canal has rich intangible cultural heritage(ICH)along its route.In the era of globalization and media convergence,using short videos to promote the canal’s... As a World Cultural Heritage site,the Beijing-Hangzhou Grand Canal has rich intangible cultural heritage(ICH)along its route.In the era of globalization and media convergence,using short videos to promote the canal’s ICH globally is important for internationalizing Chinese culture.This study uses cross-cultural communication theory,case analysis,and data research to examine the current status of short video dissemination of the canal’s ICH.It identifies core challenges in narrative techniques and cultural translation,and proposes a systematic optimization framework with five dimensions including content and platform.The findings offer both theoretical insights and practical guidance for the international promotion of ICH. 展开更多
关键词 Beijing-Hangzhou Grand Canal intangible cultural heritage short video international communication
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部