Background:Weight-related self-stigma(WRSS)is prevalent among individuals with different types of weight status and is associated with a range of negative health outcomes.Social support and coping models explain how i...Background:Weight-related self-stigma(WRSS)is prevalent among individuals with different types of weight status and is associated with a range of negative health outcomes.Social support and coping models explain how individuals may use different coping methods to deal with their mental health needs.Psychological distress(e.g.,depression and stress)could lead to overuse of social media and smartphones.When using social media or smartphones,individuals are likely to be exposed to negative comments regarding weight/shape/size posted on the social media.Consequently,individuals who experience problematic social media use(PSMU)or problematic smartphone use(PSPU)may develop WRSS.Therefore,the present study examined the roles of PSMU and PSPU as mediators in the relationship between psychological distress and WRSS.Methods:Using convenience sampling via an online survey,622 participants with a mean age of 23.70 years(SD=4.33)completed questions assessing sociodemographic variables,psychological distress,PSMU,PSPU,WRSS,and self-reported weight and height.Results:The hierarchical regression models showed that sex(β=0.08,p=0.01),BMI(β=0.39,p<0.001),depression(β=0.21,p=0.001),stress(β=0.18,p=0.01),PSMU(β=0.09,p=0.045),and PSPU(β=0.14,p=0.001)were significant factors for WRSS.Conclusion:The mediation models showed that both PSMU and PSPU were significant mediators in the relationships between depression and stress with WRSS.The present findings provide some evidence for understanding WRSS and has important implications for developing interventions to reduce its negative impact on individuals’health and well-being.展开更多
Objective:Kallmann syndrome(KS)is a rare inherited disorder characterized by congenital hypogonadotropic hypogonadism and reduced or absent olfactory function.In addition to gonadal dysgenesis and structural abnormali...Objective:Kallmann syndrome(KS)is a rare inherited disorder characterized by congenital hypogonadotropic hypogonadism and reduced or absent olfactory function.In addition to gonadal dysgenesis and structural abnormalities,KS patients may present with extensive psychosocial dysfunction and behavioral changes.This study aims to evaluate the effects of self-stigma,impulsivity,and insomnia on anxiety and depression in KS patients and to explore the interrelationships among these factors.Methods:A total of 206 patients with confirmed KS were recruited from the Xiangya Hospital and Henan Provincial People’s Hospital.Multivariable Logistic regression analysis was used to identify independent factors associated with anxiety and depression,and a serial multiple-mediator model was applied to characterize pathway effects.Results:The cohort of KS patients demonstrated substantial psychological and social burden,including self-stigma,impulsivity,insomnia,loneliness,anxiety,depression,and overall social isolation tendencies.Logistic regression analysis indicated that self-stigma(OR=1.112,P=0.003),loneliness(OR=1.198,P=0.007),and insomnia(OR=1.098,P=0.017)were independent factors the presence of anxiety and depression in KS patients.Mediation-effect modeling further showed that impulsivity and insomnia significantly mediated the effect of self-stigma on anxiety and depression in KS(indirect effect 3=0.013,P=0.008;95%CI 0.004 to 0.024;c’=0.147,P<0.001;95%CI 0.091 to 0.201).Conclusion:This study preliminarily identified the major modifiable factors associated with anxiety and depression in KS patients,including self-stigma,loneliness,and insomnia.Impulsivity and insomnia demonstrated significant serial mediation effects linking selfstigma to affective outcomes.Multidimensional intervention strategies targeting stigma reduction,impulsivity regulation,and sleep-quality improvement may help alleviate anxiety-depression symptoms and ultimately improve overall quality of life in patients with KS.展开更多
基金supported in part by(received funding from)the Ministry of Science and Technology,Taiwan(MOST 110-2410-H-006-115,MOST 111-2410-H-006-100)the National Science and Technology Council,Taiwan(NSTC 112-2410-H-006-089-SS2)+1 种基金the Higher Education Sprout Project,the Ministry of Education at the Headquarters of University Advancement at the National Cheng Kung University(NCKU)the 2021 Southeast and South Asia and Taiwan Universities Joint Research Scheme(NCKU 31).
文摘Background:Weight-related self-stigma(WRSS)is prevalent among individuals with different types of weight status and is associated with a range of negative health outcomes.Social support and coping models explain how individuals may use different coping methods to deal with their mental health needs.Psychological distress(e.g.,depression and stress)could lead to overuse of social media and smartphones.When using social media or smartphones,individuals are likely to be exposed to negative comments regarding weight/shape/size posted on the social media.Consequently,individuals who experience problematic social media use(PSMU)or problematic smartphone use(PSPU)may develop WRSS.Therefore,the present study examined the roles of PSMU and PSPU as mediators in the relationship between psychological distress and WRSS.Methods:Using convenience sampling via an online survey,622 participants with a mean age of 23.70 years(SD=4.33)completed questions assessing sociodemographic variables,psychological distress,PSMU,PSPU,WRSS,and self-reported weight and height.Results:The hierarchical regression models showed that sex(β=0.08,p=0.01),BMI(β=0.39,p<0.001),depression(β=0.21,p=0.001),stress(β=0.18,p=0.01),PSMU(β=0.09,p=0.045),and PSPU(β=0.14,p=0.001)were significant factors for WRSS.Conclusion:The mediation models showed that both PSMU and PSPU were significant mediators in the relationships between depression and stress with WRSS.The present findings provide some evidence for understanding WRSS and has important implications for developing interventions to reduce its negative impact on individuals’health and well-being.
基金supported by the Natural Science Foundation of Hunan Province(2023JJ30926)the Fundamental Research Funds for the Central Universities of Central South University(1053320220341),China。
文摘Objective:Kallmann syndrome(KS)is a rare inherited disorder characterized by congenital hypogonadotropic hypogonadism and reduced or absent olfactory function.In addition to gonadal dysgenesis and structural abnormalities,KS patients may present with extensive psychosocial dysfunction and behavioral changes.This study aims to evaluate the effects of self-stigma,impulsivity,and insomnia on anxiety and depression in KS patients and to explore the interrelationships among these factors.Methods:A total of 206 patients with confirmed KS were recruited from the Xiangya Hospital and Henan Provincial People’s Hospital.Multivariable Logistic regression analysis was used to identify independent factors associated with anxiety and depression,and a serial multiple-mediator model was applied to characterize pathway effects.Results:The cohort of KS patients demonstrated substantial psychological and social burden,including self-stigma,impulsivity,insomnia,loneliness,anxiety,depression,and overall social isolation tendencies.Logistic regression analysis indicated that self-stigma(OR=1.112,P=0.003),loneliness(OR=1.198,P=0.007),and insomnia(OR=1.098,P=0.017)were independent factors the presence of anxiety and depression in KS patients.Mediation-effect modeling further showed that impulsivity and insomnia significantly mediated the effect of self-stigma on anxiety and depression in KS(indirect effect 3=0.013,P=0.008;95%CI 0.004 to 0.024;c’=0.147,P<0.001;95%CI 0.091 to 0.201).Conclusion:This study preliminarily identified the major modifiable factors associated with anxiety and depression in KS patients,including self-stigma,loneliness,and insomnia.Impulsivity and insomnia demonstrated significant serial mediation effects linking selfstigma to affective outcomes.Multidimensional intervention strategies targeting stigma reduction,impulsivity regulation,and sleep-quality improvement may help alleviate anxiety-depression symptoms and ultimately improve overall quality of life in patients with KS.
