The Hengshan complex is located in the central part of SE China, which underwent rapid tectonic uplift in the Cretaceous just like many other complexes on the continent. （40）~Ar-（39）~Ar geochronological data from ...The Hengshan complex is located in the central part of SE China, which underwent rapid tectonic uplift in the Cretaceous just like many other complexes on the continent. （40）~Ar-（39）~Ar geochronological data from the Hengshan complex suggest that two episodes of crustal cooling/extension took place in this part of the continent during the Cretaceous time. The first stage of exhumation was active during ca. 136-125 Ma, with a cooling rate of 〉 10 ℃Ma. The second stage of exhumation happened at ca. 98-93 Ma, with a cooling rate of 〉 10 ℃/Ma. Considering the folding in the Lower Cretaceous sedimentary rocks and the regional unconformity underneath the Upper Cretaceous red beds, it is believed that the Cretaceous crustal extension in SE China was interrupted by a compressional event. The reversion to extension, shortly after this middle Cretaceous compression, led to the rapid cooling/exhumation of the Hengshan complex at ca. 98-93 Ma. The Cretaceous tectonic processes in the hinterland of SE China could be controlled by interactions between the continental margin and the Paleo-pacific plate.展开更多
The complexities of multi-wing chaotic systems based on the modified Chen system and a multi-segment quadratic function are investigated by employing the statistical complexity measure （SCM） and the spectral entropy...The complexities of multi-wing chaotic systems based on the modified Chen system and a multi-segment quadratic function are investigated by employing the statistical complexity measure （SCM） and the spectral entropy （SE） algorithm. How to choose the parameters of the SCM and SE algorithms is discussed. The results show that the complexity of the multi-wing chaotic system does not increase as the number of wings increases, and it is consistent with the results of the Grassberger-Procaccia （GP） algorithm and the largest Lyapunov exponent （LLE） of the multi-wing chaotic system.展开更多
Tumor cell resistance is one of the big hurdles limiting the therapeutic efficacy of tumor necrosis factorrelated apoptosis-inducing ligand(TRAIL)-based cancer treatment.Therefore,the development of a sa fe and effect...Tumor cell resistance is one of the big hurdles limiting the therapeutic efficacy of tumor necrosis factorrelated apoptosis-inducing ligand(TRAIL)-based cancer treatment.Therefore,the development of a sa fe and effective sensitizer agent is greatly desired for optimizing TRAIL therapy.Herein,we successfully developed a Se/Fe complex with low toxicity to highly effectively inhibit tumor cells proliferation and migration capabilities through down-regulating ER stress related selenoproteins.Furthermore,it could more efficiently damage tumor spheroids with good penetration capability.More importantly,it could synergize with TRAIL treatment to induce the robust generation of reactive oxygen species(ROS),downregulating ER stress related selenoproteins for triggering tumor cells apoptosis in extrinsic and intrinsic signaling pathways.Taken together,this study provides a potential chemo-drug and sensitizer agent to improve the therapeutic efficacy of TRAIL-based cancer treatment.展开更多
Multiple-Input Multiple-Output (MIMO) techniques are promising in wireless communication systems for its high spectral efficiency. Sphere Detector (SD) is favoured in MIMO detection to achieve Maximum-Likelihood (ML) ...Multiple-Input Multiple-Output (MIMO) techniques are promising in wireless communication systems for its high spectral efficiency. Sphere Detector (SD) is favoured in MIMO detection to achieve Maximum-Likelihood (ML) performance. In this paper, we proposed a new SD method for MIMO-Orthogonal Frequency Division Multiplexing (OFDM) systems based on IEEE802.11n, which uses Singular Value Decomposition (SVD) in complex domain to reduce the computation complexity. Furthermore, a new Schnorr-Euchner (SE) enumeration algorithm is also discussed in detail. The computer simulation result shows that the computational complexity and the number of visited nodes can be reduced significantly compared with conventional SD detectors with the same Bit Error Rate (BER) performance.展开更多
The Collaborative Cross(CC)mouse model is a next‐generation mouse genetic reference population(GRP)designated for a high‐resolution quantitative trait loci(QTL)mapping of complex traits during health and disease.The...The Collaborative Cross(CC)mouse model is a next‐generation mouse genetic reference population(GRP)designated for a high‐resolution quantitative trait loci(QTL)mapping of complex traits during health and disease.The CC lines were generated from reciprocal crosses of eight divergent mouse founder strains composed of five classical and three wild‐derived strains.Complex traits are defined to be controlled by variations within multiple genes and the gene/environment interactions.In this article,we introduce and present variety of protocols and results of studying the host response to infectious and chronic diseases,including type 2 diabetes and metabolic diseases,body composition,immune response,colorectal cancer,susceptibility to Aspergillus fumigatus,Klebsiella pneumoniae,Pseudomonas aeruginosa,sepsis,and mixed infections of Porphyromonas gingivalis and Fusobacterium nucleatum,which were conducted at our laboratory using the CC mouse population.These traits are observed at multiple levels of the body systems,including metabolism,body weight,immune profile,susceptibility or resistance to the development and progress of infectious or chronic diseases.Herein,we present full protocols and step‐by‐step methods,implemented in our laboratory for the phenotypic and genotypic characterization of the different CC lines,mapping the gene underlying the host response to these infections and chronic diseases.The CC mouse model is a unique and powerful GRP for dissecting the host genetic architectures underlying complex traits,including chronic and infectious diseases.展开更多
The Nagar Parkar complex consists of Neoproterozoic igneous and metamorphic rocks dissected by episodic mafic and felsic dykes.The latter can be classified broadly into porphyritic felsic dykes and aplitic felsic dyke...The Nagar Parkar complex consists of Neoproterozoic igneous and metamorphic rocks dissected by episodic mafic and felsic dykes.The latter can be classified broadly into porphyritic felsic dykes and aplitic felsic dykes(minor)展开更多
Acrylate terpolymer- bound Se, N bidentate ligand was synthesized fromthe side chain chlorine of copolymer and β- dimethylamino -β - hydroxyl diethyl selenoether. The polymer - supported platinum complex exhibited h...Acrylate terpolymer- bound Se, N bidentate ligand was synthesized fromthe side chain chlorine of copolymer and β- dimethylamino -β - hydroxyl diethyl selenoether. The polymer - supported platinum complex exhibited highcatalytic activity in the hodrosilylation of olefins with triethoxysilane.展开更多
Cenozoic potassic-ultrapotassic igneous rocks are widespread in the southeastern Tibetan Plateau.Their petrogenesis and magmatic processes remain subject to debate in spite of numerous publications.Almost all of the C...Cenozoic potassic-ultrapotassic igneous rocks are widespread in the southeastern Tibetan Plateau.Their petrogenesis and magmatic processes remain subject to debate in spite of numerous publications.Almost all of the Cenozoic extrusive and intrusive rocks in the Yao’an area,western Yunnan Province,SW China,are geochemically shoshonitic,collectively termed here the Yao’an Shoshonitic Complex(YSC).The YSC is located in the(south)easternmost part of the ENE-WSW-trending,~550 km-long and~250 km-wide Cenozoic magmatic zone;the latter separates the orthogonal and oblique collision belts of the India-Eurasia collision orogen.Previously published geochronological and thermochronological data revealed that the rocks of the YSC were emplaced over a short timespan of 34-32 Ma.This and our new data suggest that the primary magma of the YSC likely was formed by partial melting of ancient continental lithospheric mantle beneath the Yangtze Block.This part of the continental lithospheric mantle had likely not been modified by any oceanic subduction.Fractionation crystallization of an Mg-and Ca-bearing mineral and TiFe oxides during the magmatic evolution probably account for the variable lithologies of the YSC.展开更多
A long-term simulation experiment was carried out to study the effect of rice-based cropping system,green manure and ground-water level on soil organic matter. Soil organic matter content increased when upland soil wa...A long-term simulation experiment was carried out to study the effect of rice-based cropping system,green manure and ground-water level on soil organic matter. Soil organic matter content increased when upland soil was puddled and cropped under submerged conditions. Among all treatments, soil organic matter contents in the treatments of rice-rice-flooded fallow in winter (WF) were the highest, those in the treatments of rice-rice-astragalus (WG) came the second, and those in the treatments of rice-rice-rape (WR)were the lowest. At the same rate of green manure application, the degrees of organo-mineral complexing in soils of treatments WG and WR were higher than those of treatment WF. After 9-year rice cultivation, the state of combination of humus in heavy fraction varied with treatments. The relative content of loosely bonded humus decreased in the order of WR > WG > WF, and it correlated significantly with Se availability.展开更多
基金supported by the basic outlay of scientific research work from the Ministry of Science and Technology(DZLXJK201302)the National Science and Technology Project(SinoProbe–08–01)the Chinese National Fund of Science grant(no.41202154)
文摘The Hengshan complex is located in the central part of SE China, which underwent rapid tectonic uplift in the Cretaceous just like many other complexes on the continent. （40）~Ar-（39）~Ar geochronological data from the Hengshan complex suggest that two episodes of crustal cooling/extension took place in this part of the continent during the Cretaceous time. The first stage of exhumation was active during ca. 136-125 Ma, with a cooling rate of 〉 10 ℃Ma. The second stage of exhumation happened at ca. 98-93 Ma, with a cooling rate of 〉 10 ℃/Ma. Considering the folding in the Lower Cretaceous sedimentary rocks and the regional unconformity underneath the Upper Cretaceous red beds, it is believed that the Cretaceous crustal extension in SE China was interrupted by a compressional event. The reversion to extension, shortly after this middle Cretaceous compression, led to the rapid cooling/exhumation of the Hengshan complex at ca. 98-93 Ma. The Cretaceous tectonic processes in the hinterland of SE China could be controlled by interactions between the continental margin and the Paleo-pacific plate.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 61161006 and 61073187)
文摘The complexities of multi-wing chaotic systems based on the modified Chen system and a multi-segment quadratic function are investigated by employing the statistical complexity measure （SCM） and the spectral entropy （SE） algorithm. How to choose the parameters of the SCM and SE algorithms is discussed. The results show that the complexity of the multi-wing chaotic system does not increase as the number of wings increases, and it is consistent with the results of the Grassberger-Procaccia （GP） algorithm and the largest Lyapunov exponent （LLE） of the multi-wing chaotic system.
基金the National Natural Science Foundation of China(Nos.21877049,31871006)National Program for Support of Top-notch Young Professionals(No.W02070191)+1 种基金Major Program for Tackling Key Problems of Industrial Technology in Guangzhou(No.201902020013)Dedicated Fund for Promoting High-Quality Marine Economic Development in Guangdong Province(No.GDOE-2019-A31)。
文摘Tumor cell resistance is one of the big hurdles limiting the therapeutic efficacy of tumor necrosis factorrelated apoptosis-inducing ligand(TRAIL)-based cancer treatment.Therefore,the development of a sa fe and effective sensitizer agent is greatly desired for optimizing TRAIL therapy.Herein,we successfully developed a Se/Fe complex with low toxicity to highly effectively inhibit tumor cells proliferation and migration capabilities through down-regulating ER stress related selenoproteins.Furthermore,it could more efficiently damage tumor spheroids with good penetration capability.More importantly,it could synergize with TRAIL treatment to induce the robust generation of reactive oxygen species(ROS),downregulating ER stress related selenoproteins for triggering tumor cells apoptosis in extrinsic and intrinsic signaling pathways.Taken together,this study provides a potential chemo-drug and sensitizer agent to improve the therapeutic efficacy of TRAIL-based cancer treatment.
文摘Multiple-Input Multiple-Output (MIMO) techniques are promising in wireless communication systems for its high spectral efficiency. Sphere Detector (SD) is favoured in MIMO detection to achieve Maximum-Likelihood (ML) performance. In this paper, we proposed a new SD method for MIMO-Orthogonal Frequency Division Multiplexing (OFDM) systems based on IEEE802.11n, which uses Singular Value Decomposition (SVD) in complex domain to reduce the computation complexity. Furthermore, a new Schnorr-Euchner (SE) enumeration algorithm is also discussed in detail. The computer simulation result shows that the computational complexity and the number of visited nodes can be reduced significantly compared with conventional SD detectors with the same Bit Error Rate (BER) performance.
基金Hendrech and Eiran Gotwert FundWellcome, Grant/Award Number: 085906/Z/08/Z, 075491/Z/04 and 090532/Z/09/Z+6 种基金Tel-Aviv UniversityIsraeli Science foundation, Grant/Award Number: 429/09, 961/15 and 1085/18Binational Science Foundation, Grant/Award Number: 2015077German Israeli Science Foundation, Grant/Award Number: I-63-410.20-2017Israeli Cancer Research FundCancer Research Counsel-UK Cancer Biology Research Center
文摘The Collaborative Cross(CC)mouse model is a next‐generation mouse genetic reference population(GRP)designated for a high‐resolution quantitative trait loci(QTL)mapping of complex traits during health and disease.The CC lines were generated from reciprocal crosses of eight divergent mouse founder strains composed of five classical and three wild‐derived strains.Complex traits are defined to be controlled by variations within multiple genes and the gene/environment interactions.In this article,we introduce and present variety of protocols and results of studying the host response to infectious and chronic diseases,including type 2 diabetes and metabolic diseases,body composition,immune response,colorectal cancer,susceptibility to Aspergillus fumigatus,Klebsiella pneumoniae,Pseudomonas aeruginosa,sepsis,and mixed infections of Porphyromonas gingivalis and Fusobacterium nucleatum,which were conducted at our laboratory using the CC mouse population.These traits are observed at multiple levels of the body systems,including metabolism,body weight,immune profile,susceptibility or resistance to the development and progress of infectious or chronic diseases.Herein,we present full protocols and step‐by‐step methods,implemented in our laboratory for the phenotypic and genotypic characterization of the different CC lines,mapping the gene underlying the host response to these infections and chronic diseases.The CC mouse model is a unique and powerful GRP for dissecting the host genetic architectures underlying complex traits,including chronic and infectious diseases.
文摘The Nagar Parkar complex consists of Neoproterozoic igneous and metamorphic rocks dissected by episodic mafic and felsic dykes.The latter can be classified broadly into porphyritic felsic dykes and aplitic felsic dykes(minor)
文摘Acrylate terpolymer- bound Se, N bidentate ligand was synthesized fromthe side chain chlorine of copolymer and β- dimethylamino -β - hydroxyl diethyl selenoether. The polymer - supported platinum complex exhibited highcatalytic activity in the hodrosilylation of olefins with triethoxysilane.
基金financially supported by the Ministry of Sciences and Technology of China(Grant No.2022YFF0800901)the Natural Science Foundation of China(Grant Nos.92055206 and 42163007)。
文摘Cenozoic potassic-ultrapotassic igneous rocks are widespread in the southeastern Tibetan Plateau.Their petrogenesis and magmatic processes remain subject to debate in spite of numerous publications.Almost all of the Cenozoic extrusive and intrusive rocks in the Yao’an area,western Yunnan Province,SW China,are geochemically shoshonitic,collectively termed here the Yao’an Shoshonitic Complex(YSC).The YSC is located in the(south)easternmost part of the ENE-WSW-trending,~550 km-long and~250 km-wide Cenozoic magmatic zone;the latter separates the orthogonal and oblique collision belts of the India-Eurasia collision orogen.Previously published geochronological and thermochronological data revealed that the rocks of the YSC were emplaced over a short timespan of 34-32 Ma.This and our new data suggest that the primary magma of the YSC likely was formed by partial melting of ancient continental lithospheric mantle beneath the Yangtze Block.This part of the continental lithospheric mantle had likely not been modified by any oceanic subduction.Fractionation crystallization of an Mg-and Ca-bearing mineral and TiFe oxides during the magmatic evolution probably account for the variable lithologies of the YSC.
文摘A long-term simulation experiment was carried out to study the effect of rice-based cropping system,green manure and ground-water level on soil organic matter. Soil organic matter content increased when upland soil was puddled and cropped under submerged conditions. Among all treatments, soil organic matter contents in the treatments of rice-rice-flooded fallow in winter (WF) were the highest, those in the treatments of rice-rice-astragalus (WG) came the second, and those in the treatments of rice-rice-rape (WR)were the lowest. At the same rate of green manure application, the degrees of organo-mineral complexing in soils of treatments WG and WR were higher than those of treatment WF. After 9-year rice cultivation, the state of combination of humus in heavy fraction varied with treatments. The relative content of loosely bonded humus decreased in the order of WR > WG > WF, and it correlated significantly with Se availability.
