目的:探讨关节镜下Bankart损伤修补术联合Remplissage填塞术治疗复发性肩关节前脱位合并Hill-Sachs损伤的方法和临床疗效。方法:回顾性分析2016年3月至2019年3月行关节镜下Bankart损伤修复治疗关节盂骨缺损<20%的复发性肩关节前脱位...目的:探讨关节镜下Bankart损伤修补术联合Remplissage填塞术治疗复发性肩关节前脱位合并Hill-Sachs损伤的方法和临床疗效。方法:回顾性分析2016年3月至2019年3月行关节镜下Bankart损伤修复治疗关节盂骨缺损<20%的复发性肩关节前脱位患者106例,其中男76例,女30例;年龄18~45(27.3±8.6)岁;左肩59例,右肩47例。手术前后采用肩关节主动活动度评估关节活动范围(range of motion,ROM),采用美国肩肘外科协会(American Shoulder and Elbow Surgeons,ASES)评分,Constant-Murley评分及肩关节功能Rowe评分对肩关节功能和稳定性进行评估。结果:所有患者获得随访,均取得满意疗效,术后随访时间21~60(41.5±18.5)个月。1例术后出现感染,再次关节镜清理后感染控制,其余患者均未出现感染、关节腔积血及再脱位等临床并发症。肩关节前屈上举由术前的(158.33±15.72)°提高至末次随访的(169.43±10.04)°,内旋由术前T7(T4-T10)改变至末次随访T8(T5-T10);平均体侧外旋、外展90°外旋分别由术前(58.46±15.51)°及(99.37±14.09)°减小至末次随访的(53.18±14.90)°及(92.52±13.10)°。ASES评分、Constant-Murley评分及Rowe评分均较术前明显改善。结论:关节镜下Bankart损伤修补联合Remplissage填塞术治疗合并Hill-Sachs缺损的成年人复发性肩关节前脱位临床效果满意,虽然外旋功能较术前减弱,但能够有效重建肩关节功能,避免术后再脱位的发生。展开更多
背景Remplissage手术可显著降低肩关节Bankart损伤合并Hill-Sachs损伤术后脱位复发率。但该术式对肩关节外旋功能的影响尚无统一意见。目的系统评价关节镜下Remplissage手术对肩关节Bankart损伤合并Hill-Sachs损伤患者肩关节外旋功能的...背景Remplissage手术可显著降低肩关节Bankart损伤合并Hill-Sachs损伤术后脱位复发率。但该术式对肩关节外旋功能的影响尚无统一意见。目的系统评价关节镜下Remplissage手术对肩关节Bankart损伤合并Hill-Sachs损伤患者肩关节外旋功能的影响。方法检索知网、万方、维普、PubMed、Embase、Web of Science数据库2008年5月-2019年12月发表的与Remplissage手术相关的中英文文献。根据非随机对照实验方法学评价指标(MINORS)进行文献质量评价,分析Remplissage手术对肩关节外旋功能的影响。结果本研究共纳入文献15篇,其中英文文献10篇(66.7%),中文文献5篇(33.3%),证据等级Ⅲ级文献3篇(20%),Ⅳ级文献12篇(80%)。共纳入673例患者(674肩),其中Remplissage+Bankart损伤修复术(B+R)546例(81.1%),单纯Bankart手术(B)127例(18.9%)。Meta结果显示,Remplissage+Bankart(B+R)修复术后,肩关节体侧外旋活动受限平均8.6o(P<0.001),90o外展外旋功能较术前无统计学差异(P=0.054)。Remplissage+Bankart损伤修复术(B+R)与单纯Bankart损伤修复术(B)比较,前者肩关节外旋受限稍重,两者外旋受限相差0.74o,差异无统计学意义(P=0.078)。结论Remplissage+Bankart损伤修复术后肩关节外旋功能部分受限,应根据伤情选择手术适应证。展开更多
Background: Late- onset Tay- Sachs disease (LOTS) is an adult- onset, autosomal recessive, progressive variant of GM2 gangliosidosis, characterized by involvement of the cerebellum and anterior horn cells. Objective: ...Background: Late- onset Tay- Sachs disease (LOTS) is an adult- onset, autosomal recessive, progressive variant of GM2 gangliosidosis, characterized by involvement of the cerebellum and anterior horn cells. Objective: To determine the range of visual and ocular motor abnormalities in LOTS, as a prelude to evaluating the effectiveness of novel therapies. Methods: Fourteen patients with biochemically confirmed LOTS (8 men; age range 24 to 53 years; disease duration 5 to 30 years) and 10 age- matched control subjects were studied. Snellen visual acuity, contrast sensitivity, color vision, stereopsis, and visual fields were measured, and optic fundi were photographed. Horizontal and vertical eye movements (search coil) were recorded, and saccades, pursuit, vestibulo- ocular reflex (VOR), vergence, and optokinetic (OK) responses were measured. Results: All patients showed normal visual functions and optic fundi. The main eye movement abnormality concerned saccades, which were “ multistep,” consisting of a series of small saccades and larger movements that showed transient decelerations. Larger saccades ended earlier and more abruptly (greater peak deceleration) in LOTS patients than in control subjects; these changes can be attributed to premature termination of the saccadic pulse. Smooth- pursuit and slow- phase OK gains were reduced, but VOR, vergence, and gaze holding were normal. Conclusions: Patients with late- onset Tay- Sachs disease (LOTS) show characteristic abnormalities of saccades but normal afferent visual systems. Hypometria, transient decelerations, and premature termination of saccades suggest disruption of a “ latch circuit” that normally inhibits pontine omnipause neurons, permitting burst neurons to discharge until the eye movement is completed. These measurable abnormalities of saccades provide a means to evaluate the effects of novel treatments for LOTS.展开更多
文摘目的:探讨关节镜下Bankart损伤修补术联合Remplissage填塞术治疗复发性肩关节前脱位合并Hill-Sachs损伤的方法和临床疗效。方法:回顾性分析2016年3月至2019年3月行关节镜下Bankart损伤修复治疗关节盂骨缺损<20%的复发性肩关节前脱位患者106例,其中男76例,女30例;年龄18~45(27.3±8.6)岁;左肩59例,右肩47例。手术前后采用肩关节主动活动度评估关节活动范围(range of motion,ROM),采用美国肩肘外科协会(American Shoulder and Elbow Surgeons,ASES)评分,Constant-Murley评分及肩关节功能Rowe评分对肩关节功能和稳定性进行评估。结果:所有患者获得随访,均取得满意疗效,术后随访时间21~60(41.5±18.5)个月。1例术后出现感染,再次关节镜清理后感染控制,其余患者均未出现感染、关节腔积血及再脱位等临床并发症。肩关节前屈上举由术前的(158.33±15.72)°提高至末次随访的(169.43±10.04)°,内旋由术前T7(T4-T10)改变至末次随访T8(T5-T10);平均体侧外旋、外展90°外旋分别由术前(58.46±15.51)°及(99.37±14.09)°减小至末次随访的(53.18±14.90)°及(92.52±13.10)°。ASES评分、Constant-Murley评分及Rowe评分均较术前明显改善。结论:关节镜下Bankart损伤修补联合Remplissage填塞术治疗合并Hill-Sachs缺损的成年人复发性肩关节前脱位临床效果满意,虽然外旋功能较术前减弱,但能够有效重建肩关节功能,避免术后再脱位的发生。
文摘背景Remplissage手术可显著降低肩关节Bankart损伤合并Hill-Sachs损伤术后脱位复发率。但该术式对肩关节外旋功能的影响尚无统一意见。目的系统评价关节镜下Remplissage手术对肩关节Bankart损伤合并Hill-Sachs损伤患者肩关节外旋功能的影响。方法检索知网、万方、维普、PubMed、Embase、Web of Science数据库2008年5月-2019年12月发表的与Remplissage手术相关的中英文文献。根据非随机对照实验方法学评价指标(MINORS)进行文献质量评价,分析Remplissage手术对肩关节外旋功能的影响。结果本研究共纳入文献15篇,其中英文文献10篇(66.7%),中文文献5篇(33.3%),证据等级Ⅲ级文献3篇(20%),Ⅳ级文献12篇(80%)。共纳入673例患者(674肩),其中Remplissage+Bankart损伤修复术(B+R)546例(81.1%),单纯Bankart手术(B)127例(18.9%)。Meta结果显示,Remplissage+Bankart(B+R)修复术后,肩关节体侧外旋活动受限平均8.6o(P<0.001),90o外展外旋功能较术前无统计学差异(P=0.054)。Remplissage+Bankart损伤修复术(B+R)与单纯Bankart损伤修复术(B)比较,前者肩关节外旋受限稍重,两者外旋受限相差0.74o,差异无统计学意义(P=0.078)。结论Remplissage+Bankart损伤修复术后肩关节外旋功能部分受限,应根据伤情选择手术适应证。
文摘Background: Late- onset Tay- Sachs disease (LOTS) is an adult- onset, autosomal recessive, progressive variant of GM2 gangliosidosis, characterized by involvement of the cerebellum and anterior horn cells. Objective: To determine the range of visual and ocular motor abnormalities in LOTS, as a prelude to evaluating the effectiveness of novel therapies. Methods: Fourteen patients with biochemically confirmed LOTS (8 men; age range 24 to 53 years; disease duration 5 to 30 years) and 10 age- matched control subjects were studied. Snellen visual acuity, contrast sensitivity, color vision, stereopsis, and visual fields were measured, and optic fundi were photographed. Horizontal and vertical eye movements (search coil) were recorded, and saccades, pursuit, vestibulo- ocular reflex (VOR), vergence, and optokinetic (OK) responses were measured. Results: All patients showed normal visual functions and optic fundi. The main eye movement abnormality concerned saccades, which were “ multistep,” consisting of a series of small saccades and larger movements that showed transient decelerations. Larger saccades ended earlier and more abruptly (greater peak deceleration) in LOTS patients than in control subjects; these changes can be attributed to premature termination of the saccadic pulse. Smooth- pursuit and slow- phase OK gains were reduced, but VOR, vergence, and gaze holding were normal. Conclusions: Patients with late- onset Tay- Sachs disease (LOTS) show characteristic abnormalities of saccades but normal afferent visual systems. Hypometria, transient decelerations, and premature termination of saccades suggest disruption of a “ latch circuit” that normally inhibits pontine omnipause neurons, permitting burst neurons to discharge until the eye movement is completed. These measurable abnormalities of saccades provide a means to evaluate the effects of novel treatments for LOTS.
