Based on S-rough sets(singular rough sets), this paper presents function S-rough sets (function singular rough sets)and its mathematical structures and features. Function S-rough sets has two forms: function one ...Based on S-rough sets(singular rough sets), this paper presents function S-rough sets (function singular rough sets)and its mathematical structures and features. Function S-rough sets has two forms: function one direction S-rough sets (function one direction singular rough sets) and function two direction S-rough sets (function two direction singular rough sets). This paper advances the relationship theorem of function S-rough sets and S-rough sets. Function S-rough sets is the general form of S-rough sets, and S-rough sets is the special ease of function S-rough sets. In this paper, applications of function S-rough sets in rough law mining-discovery of system are given. Function S-rough sets is a new research direction of rough sets and rough system.展开更多
Function S-rough sets (function singular rough sets) is defined on a -function equivalence class [u]. Function S-rough sets is the extension form of S-rough sets. By using the function S-rough sets, this paper gives...Function S-rough sets (function singular rough sets) is defined on a -function equivalence class [u]. Function S-rough sets is the extension form of S-rough sets. By using the function S-rough sets, this paper gives rough law generation model of a-function equivalence class, discussion on law mining and law discovery in systems, and application of law mining and law discovery in communication system. Function S-rough sets is a new theory and method in law mining research.展开更多
The conceptions of the knowledge screen generated by S-rough sets are given:f-screen and f^(-)-screen,and then puts forward f^(-)-filter theorem,f^(-)-filter theorem of knowledge.At last,the applications of knowledge ...The conceptions of the knowledge screen generated by S-rough sets are given:f-screen and f^(-)-screen,and then puts forward f^(-)-filter theorem,f^(-)-filter theorem of knowledge.At last,the applications of knowledge separation are given according to f^(-)-screen and f^(-)-screen.展开更多
Singular rough sets (S-rough sets) have three classes of forms: one-directional S-rough sets, dual of onedirectional S-rough sets, and two-directional S-rough sets. Dynamic, hereditary, mnemonic, and hiding propert...Singular rough sets (S-rough sets) have three classes of forms: one-directional S-rough sets, dual of onedirectional S-rough sets, and two-directional S-rough sets. Dynamic, hereditary, mnemonic, and hiding properties are the basic characteristics of S-rough sets. By using the S-rough sets, the concepts of f-hiding knowledge, F-hiding knowledge, hiding degree, and hiding dependence degree are given. Then, both the hiding theorem and the hiding dependence theorem of hiding knowledge are proposed. Finally, an application of hiding knowledge is discussed.展开更多
Function S-rough sets(Function Singular rough sets) are defined by R-function equivalence class which has dynamic characteristic, and a function is s law, function S-rough sets have law characteristic. Function S-roug...Function S-rough sets(Function Singular rough sets) are defined by R-function equivalence class which has dynamic characteristic, and a function is s law, function S-rough sets have law characteristic. Function S-rough sets has these forms: function one direction S-rough sets, function two direction S-rough sets and dual of function one direction S-rough sets. This paper presents the law characteristic of function one direction S-rough sets and puts forward the theorems of law-chain-attribute and law-belt. Function S-rough sets is s new research direction of the rough sets theory.展开更多
Function S-rough sets has the properties of dynamics, heredity, and memory. Function S-rough sets is penetrated and crossed with the issue of economic law forecast, then a new forecast model based on function S-rough ...Function S-rough sets has the properties of dynamics, heredity, and memory. Function S-rough sets is penetrated and crossed with the issue of economic law forecast, then a new forecast model based on function S-rough sets namely the two law forecast model is proposed, which includes upper law forecast model and lower law forecast model; and its' implement algorithm is given. Finally, the validity of the model is demonstrated by the forecast for region economic development of Hainan Province.展开更多
Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar...Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar abort trajectory and leverages its advantageous properties to address the optimization design problem of abort trajectories.Initially,a solution set of all feasible abort trajectories,originating from an abort point on the nominal trajectory and complying with fundamental reentry constraints,is formulated through the introduction of two novel design parameters.Subsequently,the geometric characteristics of the solution set,as well as the distributional properties of key iterative constraint responses,including flight time and velocity increment,are analyzed.Finally,the characteristics exhibited in the solution set are employed to directly identify the design parameters of the abort trajectories with minimum flight time and velocity increment,thereby providing solutions to two distinct types of optimization problems.The simulation results for a variety of nominal trajectories,encompassing the reconstruction and redesign of the Apollo13 abort trajectory,validate the proposed method,demonstrating its ability to directly generate optimal abort trajectories.The method proposed in this paper investigates feasible abort trajectories from a global perspective,providing both a framework and convenience for mission planning and iterative optimization in abort trajectory design.展开更多
Objectives:Tamoxifen is a key drug that provides endocrine therapy for estrogen receptor(ER)α-positive breast cancer;however,resistance remains a significant clinical challenge.This study aims to investigate the mole...Objectives:Tamoxifen is a key drug that provides endocrine therapy for estrogen receptor(ER)α-positive breast cancer;however,resistance remains a significant clinical challenge.This study aims to investigate the molecular mechanisms of tamoxifen resistance in ERα-positive breast cancer,with particular focus on the role of SET Domain Containing 1A(SETD1A)-driven forkhead box A2(FOXA2)as a key regulator of this resistance.Methods:FOXA2 expression and its regulation by SETD1A were assessed via(quantitative polymerase chain reaction),western blotting,transcriptome profiling,and chromatin immunoprecipitation analyses.The effects of FOXA2 on cell proliferation,migration,invasion,and cancer stem cell traits were evaluated using small interfering RNA(siRNA)-mediated silencing.Clinical relevance was examined by analyzing patient datasets and tumor tissue microarrays.Results:FOXA2 expression was significantly elevated in tamoxifen-resistant(TamR)and ERα-negative breast cancer cells compared to that in ERα-positive MCF-7 cells,regardless of tamoxifen treatment or ERαdepletion.Transcriptome and chromatin immunoprecipitation analyses revealed that SETD1A,a histone methyltransferase,directly regulated FOXA2 expression.Functionally,FOXA2 knockdown inhibited the proliferation,migration,invasion,and cancer stem cell properties of TamR cells while restoring tamoxifen sensitivity.High FOXA2 expression was correlated with poor survival and reduced responsiveness to tamoxifen in patients with ER-positive breast cancer.Conclusion:Our findings identified FOXA2 as a key mediator of tamoxifen resistance regulated by SETD1A and suggested that targeting the SETD1A-FOXA2 axis may offer a novel strategy for overcoming endocrine resistance in breast cancer.展开更多
By introducing element equivalence class that proposes dynamic characteristic into Pawlak Z rough sets theory, the first author of this paper improved Pawlak Z rough sets and put forward S-rough sets (singular rough ...By introducing element equivalence class that proposes dynamic characteristic into Pawlak Z rough sets theory, the first author of this paper improved Pawlak Z rough sets and put forward S-rough sets (singular rough sets). S-rough sets are defined by element equivalence class that proposes dynamic characteristic. S-rough sets have dynamic characteristic. By introducing the function equivalence class (law equivalence class) that proposes dynamic characteristic into S-rough sets, the first author improved S-rough sets and put forward function S-rough sets (function singular rough sets). Function S-rough sets have dynamic characteristic and law characteristic, and a function is a law. By using function S-rough sets, this paper presents law identification, law identification theorem, and law identification criterion and applications. Function S-rough sets are a new research direction of rough sets theory, and it is also a new tool to the research of system law identification.展开更多
Function S-rbugh sets are defined by R-function equivalence class,which have dynamic characteristic.Function S-rough sets have dynamic characteristic,law characteristic and law-hiding characteristic.Function S-rough s...Function S-rbugh sets are defined by R-function equivalence class,which have dynamic characteristic.Function S-rough sets have dynamic characteristic,law characteristic and law-hiding characteristic.Function S-rough sets can generate f-hiding law and f-hiding law.By engrafting,crossing,and penetrating between the information security theory and function S-rough sets,the security hiding and the authentication of f-hiding law and f-hiding law are given respectively in this paper.The fusion and share between function S-rough sets and information security theory is a new research direction of the application of information law in information system.展开更多
In view of certain defects of common rough communication, using the S-rough sets, this article presents a S-rough communication model. The S-rough communication model is the extension of the common rough communication...In view of certain defects of common rough communication, using the S-rough sets, this article presents a S-rough communication model. The S-rough communication model is the extension of the common rough communication model. S-rough communication has two kinds of forms: one-direction S-rough communication and two-direction S-rough communication. The mathematical structure and characteristics of the one-direction S-rough communication and the two-direction S-rough communication, the relationship theorem between the one-direction S-rough communication and the two-direction S-rough communication are also presented. The S-rough communication is a dynamic communication method, and it is a novel research direction in rough sets field.展开更多
Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pP...Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pPyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such uncertainties.This study investigates the elementary notions of pPyFHSS including its set-theoretic operations union,intersection,complement,OR-and AND-operations.Some results related to these operations are also modified for pPyFHSS.Additionally,the similarity measures between pPyFHSSs are formulated with the assistance of numerical examples and results.Lastly,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested system.The algorithmic results are compared with the most pertinent model to evaluate the adaptability of pPyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical models.Similarly,while considering significant evaluating factors,the flexibility of pPyFHSS is observed through structural comparison.展开更多
基金This project was surpported by the Natural Science Foundation of Shandong Province of China (Y2004A94)
文摘Based on S-rough sets(singular rough sets), this paper presents function S-rough sets (function singular rough sets)and its mathematical structures and features. Function S-rough sets has two forms: function one direction S-rough sets (function one direction singular rough sets) and function two direction S-rough sets (function two direction singular rough sets). This paper advances the relationship theorem of function S-rough sets and S-rough sets. Function S-rough sets is the general form of S-rough sets, and S-rough sets is the special ease of function S-rough sets. In this paper, applications of function S-rough sets in rough law mining-discovery of system are given. Function S-rough sets is a new research direction of rough sets and rough system.
基金This project was supported by Natural Science Foundation of Shandong Province of China (Y2004A04), Natural ScienceFoundation of Fujian of China (Z051049) and Education Foundation of Fujian of China (JA04268),.
文摘Function S-rough sets (function singular rough sets) is defined on a -function equivalence class [u]. Function S-rough sets is the extension form of S-rough sets. By using the function S-rough sets, this paper gives rough law generation model of a-function equivalence class, discussion on law mining and law discovery in systems, and application of law mining and law discovery in communication system. Function S-rough sets is a new theory and method in law mining research.
基金supported by the National Natural Science Foundation of China(70271048).
文摘The conceptions of the knowledge screen generated by S-rough sets are given:f-screen and f^(-)-screen,and then puts forward f^(-)-filter theorem,f^(-)-filter theorem of knowledge.At last,the applications of knowledge separation are given according to f^(-)-screen and f^(-)-screen.
基金supported by the National Natural Science Foundation of China (60364001,70461001)the Hainan Provincial Natural Science Foundation of China (807054)Hainan Provincial Education Office Foundation (HJ 2008-56)
文摘Singular rough sets (S-rough sets) have three classes of forms: one-directional S-rough sets, dual of onedirectional S-rough sets, and two-directional S-rough sets. Dynamic, hereditary, mnemonic, and hiding properties are the basic characteristics of S-rough sets. By using the S-rough sets, the concepts of f-hiding knowledge, F-hiding knowledge, hiding degree, and hiding dependence degree are given. Then, both the hiding theorem and the hiding dependence theorem of hiding knowledge are proposed. Finally, an application of hiding knowledge is discussed.
基金Supported by the Nature Science Foundation of Henan Province(0511012700).
文摘Function S-rough sets(Function Singular rough sets) are defined by R-function equivalence class which has dynamic characteristic, and a function is s law, function S-rough sets have law characteristic. Function S-rough sets has these forms: function one direction S-rough sets, function two direction S-rough sets and dual of function one direction S-rough sets. This paper presents the law characteristic of function one direction S-rough sets and puts forward the theorems of law-chain-attribute and law-belt. Function S-rough sets is s new research direction of the rough sets theory.
基金supported by the National Natural Science Foundation of China (60364001, 70461004)the Hainan Provincial Natural Science Foundation of China (807054)Hainan Provincial Eduction Office Foundation (HJ2008-56).
文摘Function S-rough sets has the properties of dynamics, heredity, and memory. Function S-rough sets is penetrated and crossed with the issue of economic law forecast, then a new forecast model based on function S-rough sets namely the two law forecast model is proposed, which includes upper law forecast model and lower law forecast model; and its' implement algorithm is given. Finally, the validity of the model is demonstrated by the forecast for region economic development of Hainan Province.
文摘Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar abort trajectory and leverages its advantageous properties to address the optimization design problem of abort trajectories.Initially,a solution set of all feasible abort trajectories,originating from an abort point on the nominal trajectory and complying with fundamental reentry constraints,is formulated through the introduction of two novel design parameters.Subsequently,the geometric characteristics of the solution set,as well as the distributional properties of key iterative constraint responses,including flight time and velocity increment,are analyzed.Finally,the characteristics exhibited in the solution set are employed to directly identify the design parameters of the abort trajectories with minimum flight time and velocity increment,thereby providing solutions to two distinct types of optimization problems.The simulation results for a variety of nominal trajectories,encompassing the reconstruction and redesign of the Apollo13 abort trajectory,validate the proposed method,demonstrating its ability to directly generate optimal abort trajectories.The method proposed in this paper investigates feasible abort trajectories from a global perspective,providing both a framework and convenience for mission planning and iterative optimization in abort trajectory design.
基金supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF),funded by the Ministry of Education(RS-2023-00248378 and NRF-2020R1A6A1A03043708).
文摘Objectives:Tamoxifen is a key drug that provides endocrine therapy for estrogen receptor(ER)α-positive breast cancer;however,resistance remains a significant clinical challenge.This study aims to investigate the molecular mechanisms of tamoxifen resistance in ERα-positive breast cancer,with particular focus on the role of SET Domain Containing 1A(SETD1A)-driven forkhead box A2(FOXA2)as a key regulator of this resistance.Methods:FOXA2 expression and its regulation by SETD1A were assessed via(quantitative polymerase chain reaction),western blotting,transcriptome profiling,and chromatin immunoprecipitation analyses.The effects of FOXA2 on cell proliferation,migration,invasion,and cancer stem cell traits were evaluated using small interfering RNA(siRNA)-mediated silencing.Clinical relevance was examined by analyzing patient datasets and tumor tissue microarrays.Results:FOXA2 expression was significantly elevated in tamoxifen-resistant(TamR)and ERα-negative breast cancer cells compared to that in ERα-positive MCF-7 cells,regardless of tamoxifen treatment or ERαdepletion.Transcriptome and chromatin immunoprecipitation analyses revealed that SETD1A,a histone methyltransferase,directly regulated FOXA2 expression.Functionally,FOXA2 knockdown inhibited the proliferation,migration,invasion,and cancer stem cell properties of TamR cells while restoring tamoxifen sensitivity.High FOXA2 expression was correlated with poor survival and reduced responsiveness to tamoxifen in patients with ER-positive breast cancer.Conclusion:Our findings identified FOXA2 as a key mediator of tamoxifen resistance regulated by SETD1A and suggested that targeting the SETD1A-FOXA2 axis may offer a novel strategy for overcoming endocrine resistance in breast cancer.
基金the National Natural Science Foundation of China (Grant No. 60364001)the key Project of Chinese Ministry of Education (Grant No. 206089)the Natural Science Foundation of Shandong Province of China (Grant No. Y2007H02)
文摘By introducing element equivalence class that proposes dynamic characteristic into Pawlak Z rough sets theory, the first author of this paper improved Pawlak Z rough sets and put forward S-rough sets (singular rough sets). S-rough sets are defined by element equivalence class that proposes dynamic characteristic. S-rough sets have dynamic characteristic. By introducing the function equivalence class (law equivalence class) that proposes dynamic characteristic into S-rough sets, the first author improved S-rough sets and put forward function S-rough sets (function singular rough sets). Function S-rough sets have dynamic characteristic and law characteristic, and a function is a law. By using function S-rough sets, this paper presents law identification, law identification theorem, and law identification criterion and applications. Function S-rough sets are a new research direction of rough sets theory, and it is also a new tool to the research of system law identification.
基金the National Natural Science Foundation of China(Grant No.10771073)the Natural Science Foundation of Shandong Province(Grant No.Y2004A04)
文摘Function S-rbugh sets are defined by R-function equivalence class,which have dynamic characteristic.Function S-rough sets have dynamic characteristic,law characteristic and law-hiding characteristic.Function S-rough sets can generate f-hiding law and f-hiding law.By engrafting,crossing,and penetrating between the information security theory and function S-rough sets,the security hiding and the authentication of f-hiding law and f-hiding law are given respectively in this paper.The fusion and share between function S-rough sets and information security theory is a new research direction of the application of information law in information system.
基金This project was supported by the Natural Science Foundation of Shandong Province of China (Y2004A04)the Natural Science Foundation of Fujian Province of China (A0410026).
文摘In view of certain defects of common rough communication, using the S-rough sets, this article presents a S-rough communication model. The S-rough communication model is the extension of the common rough communication model. S-rough communication has two kinds of forms: one-direction S-rough communication and two-direction S-rough communication. The mathematical structure and characteristics of the one-direction S-rough communication and the two-direction S-rough communication, the relationship theorem between the one-direction S-rough communication and the two-direction S-rough communication are also presented. The S-rough communication is a dynamic communication method, and it is a novel research direction in rough sets field.
基金supported by the Deanship of Graduate Studies and Scientific Research at Qassim University(QU-APC-2024-9/1).
文摘Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pPyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such uncertainties.This study investigates the elementary notions of pPyFHSS including its set-theoretic operations union,intersection,complement,OR-and AND-operations.Some results related to these operations are also modified for pPyFHSS.Additionally,the similarity measures between pPyFHSSs are formulated with the assistance of numerical examples and results.Lastly,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested system.The algorithmic results are compared with the most pertinent model to evaluate the adaptability of pPyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical models.Similarly,while considering significant evaluating factors,the flexibility of pPyFHSS is observed through structural comparison.