Two new Cu(II)and Co(II)-based coordination polymers with the chemical formulae of{Cu(L)2]·DMF}n(1)and{[Co(L)2]·2DMF}n(2)have been successfully constructed from a pyridine-substituted N-heterocyclic thioamid...Two new Cu(II)and Co(II)-based coordination polymers with the chemical formulae of{Cu(L)2]·DMF}n(1)and{[Co(L)2]·2DMF}n(2)have been successfully constructed from a pyridine-substituted N-heterocyclic thioamide ligand,namely[3,4?-bipyridine]-2?-thiol(HL).Complex 1 is composed of two identical coordination networks with dia topology interpenetrating into each other,and shows 1-D microporous channels along the a axis.Complex 2 is assembled by 2-D square-grid layers stacked in an eclipsed fashion to give 1-D large square channels along the b axis.CCK-8 was used for the detection of cancer cells.Results indicated that compound 1 exhibited stronger anti-cancer activity than compound 2 on the H1650 cancer cells.The Annexin V-FITC/PI was recommended for cancer cell apoptosis,and the western blot was applied for the detection of PI3K/AKT pathway activation.展开更多
Chiral S,P-donor ferrocene-derived ligands were synthesized and applied in the asymmetric hydrogenation of quinolines using the [Ir(COD)Cl]2/S,P-ligand c omplex a s the catalyst in the presence of iodine. The effects ...Chiral S,P-donor ferrocene-derived ligands were synthesized and applied in the asymmetric hydrogenation of quinolines using the [Ir(COD)Cl]2/S,P-ligand c omplex a s the catalyst in the presence of iodine. The effects of the solvent and hydroge n pressure on conversion and enantioselectivity were examined, and up to 82% ee was obtained. The planar chirality plays an important role in this reaction. R- and S-enantiomers of 1,2,3,4-tetrahydroquinoline derivatives were ob tained using ligands 3 and 5, respectively.展开更多
目的为了便于活体肾移植供者的管理,设计并应用了活体肾移植供者信息管理系统。方法系统采用三层架构作为系统框架、B/S结构作为系统网络结构,选取Java作为开发语言,Java EE作为开发平台,采用SQL Server 2014进行数据库管理,本系统包括...目的为了便于活体肾移植供者的管理,设计并应用了活体肾移植供者信息管理系统。方法系统采用三层架构作为系统框架、B/S结构作为系统网络结构,选取Java作为开发语言,Java EE作为开发平台,采用SQL Server 2014进行数据库管理,本系统包括患者信息管理、术前评估管理、围术期信息管理、随访管理、健康教育管理、统计查询以及系统管理七个模块。结果系统运行稳定、可靠,输入数据简单、快捷,查询、统计方便。结论通过系统对供者信息进行有效管理和规划,保障了供者近期和远期安全,提高了临床工作效率。展开更多
基金the Industrial Research Project of Science and Technology,Department of Shaanxi Province(No.2017GY-126)。
文摘Two new Cu(II)and Co(II)-based coordination polymers with the chemical formulae of{Cu(L)2]·DMF}n(1)and{[Co(L)2]·2DMF}n(2)have been successfully constructed from a pyridine-substituted N-heterocyclic thioamide ligand,namely[3,4?-bipyridine]-2?-thiol(HL).Complex 1 is composed of two identical coordination networks with dia topology interpenetrating into each other,and shows 1-D microporous channels along the a axis.Complex 2 is assembled by 2-D square-grid layers stacked in an eclipsed fashion to give 1-D large square channels along the b axis.CCK-8 was used for the detection of cancer cells.Results indicated that compound 1 exhibited stronger anti-cancer activity than compound 2 on the H1650 cancer cells.The Annexin V-FITC/PI was recommended for cancer cell apoptosis,and the western blot was applied for the detection of PI3K/AKT pathway activation.
文摘Chiral S,P-donor ferrocene-derived ligands were synthesized and applied in the asymmetric hydrogenation of quinolines using the [Ir(COD)Cl]2/S,P-ligand c omplex a s the catalyst in the presence of iodine. The effects of the solvent and hydroge n pressure on conversion and enantioselectivity were examined, and up to 82% ee was obtained. The planar chirality plays an important role in this reaction. R- and S-enantiomers of 1,2,3,4-tetrahydroquinoline derivatives were ob tained using ligands 3 and 5, respectively.
文摘目的为了便于活体肾移植供者的管理,设计并应用了活体肾移植供者信息管理系统。方法系统采用三层架构作为系统框架、B/S结构作为系统网络结构,选取Java作为开发语言,Java EE作为开发平台,采用SQL Server 2014进行数据库管理,本系统包括患者信息管理、术前评估管理、围术期信息管理、随访管理、健康教育管理、统计查询以及系统管理七个模块。结果系统运行稳定、可靠,输入数据简单、快捷,查询、统计方便。结论通过系统对供者信息进行有效管理和规划,保障了供者近期和远期安全,提高了临床工作效率。
