Introduction: Seizures are one of the most common neurological complications in the infant period. The aim of our study was to describe the epidemiological, clinical, therapeutic and prognostic features of seizures in...Introduction: Seizures are one of the most common neurological complications in the infant period. The aim of our study was to describe the epidemiological, clinical, therapeutic and prognostic features of seizures in infants at the Albert Royer Children’s Hospital (Senegal). Materials and Methods: This was a retrospective, descriptive study from 1 January 2012 to 30 September 2018 of infants aged 0 days to 2 months who presented with seizures. Results: The hospital rate was 8.5%. Almost all the mothers (99.1%) had undergone at least 3 antenatal visits. Urogenital infection, gestational arterial hypertension and funicular anomalies were the main pregnancy-related pathologies. Delivery was vaginal in the majority of cases (80.9%). Most infants (43.6%) had not cried at birth. The majority of infants (63%) were born at term. Trophicity was normal in 68% of cases. The average age of the infants was 6.7 days. The main causes of seizures were hypoxic-ischemic encephalopathy (48.7%), metabolic disturbances (48.1%) and central ոеrvοսѕ system infections (15.6%). Phenobarbital was the 1st-line anticonvulsant. The case fatality rate was 39.5%. The main sequela observed were delayed psychomotor development (20.6%). Conclusion: Optimal management of infant seizures requires early diagnosis and etiological treatment by improving the quality of perinatal care to ensure better management of risk factors, as well as increasing the availability of neuroimaging equipment.展开更多
为推进有关医学科学、诊疗技术和公共卫生的历史研究,加强世界各国医学史研究人员和学会之间的交流,促进医学文化的交流与传播,国际医学史学会(International Society for the History of Medicine,ISHM)于1921年在巴黎宣布成立。利用I...为推进有关医学科学、诊疗技术和公共卫生的历史研究,加强世界各国医学史研究人员和学会之间的交流,促进医学文化的交流与传播,国际医学史学会(International Society for the History of Medicine,ISHM)于1921年在巴黎宣布成立。利用ISHM的相关档案和口述访谈等辅助资料,还原其建立和演进的过程,并在全球政治和医学发展格局中,批判性地审视ISHM从以法国和比利时为主导,逐步走向欧洲大陆、欧洲和北美,最后走向全球,从以医生/医学史家为主体到融合科学技术史、生物医学史、医疗史和历史学家等多元学科的历史进程。展开更多
荷兰莱顿世界博物馆(Leiden World Museum)收藏着18世纪70年代初荷兰海牙律师简·西奥多·罗也(Jean Theodore Royer)专门从广州订制和购买的,包括2000多幅绘画作品在内的人工制品,这批私人订制种类繁多,是当年日益繁荣的广州...荷兰莱顿世界博物馆(Leiden World Museum)收藏着18世纪70年代初荷兰海牙律师简·西奥多·罗也(Jean Theodore Royer)专门从广州订制和购买的,包括2000多幅绘画作品在内的人工制品,这批私人订制种类繁多,是当年日益繁荣的广州贸易的副产品,更是多重历史的产物。它既是18世纪西方世界罕见的关于遥远中国的知识研究型收集,反映了17—18世纪荷兰的科学发展和文化追求,尤其是罗也藏品中的绘画图册,作为18世纪中叶之后日益成熟的广州外销画作品,凸显出日益明显的外销画特点,是近代早期中西美术交流史上的重要作品;也是具有重要文化价值的历史记录。展开更多
文摘Introduction: Seizures are one of the most common neurological complications in the infant period. The aim of our study was to describe the epidemiological, clinical, therapeutic and prognostic features of seizures in infants at the Albert Royer Children’s Hospital (Senegal). Materials and Methods: This was a retrospective, descriptive study from 1 January 2012 to 30 September 2018 of infants aged 0 days to 2 months who presented with seizures. Results: The hospital rate was 8.5%. Almost all the mothers (99.1%) had undergone at least 3 antenatal visits. Urogenital infection, gestational arterial hypertension and funicular anomalies were the main pregnancy-related pathologies. Delivery was vaginal in the majority of cases (80.9%). Most infants (43.6%) had not cried at birth. The majority of infants (63%) were born at term. Trophicity was normal in 68% of cases. The average age of the infants was 6.7 days. The main causes of seizures were hypoxic-ischemic encephalopathy (48.7%), metabolic disturbances (48.1%) and central ոеrvοսѕ system infections (15.6%). Phenobarbital was the 1st-line anticonvulsant. The case fatality rate was 39.5%. The main sequela observed were delayed psychomotor development (20.6%). Conclusion: Optimal management of infant seizures requires early diagnosis and etiological treatment by improving the quality of perinatal care to ensure better management of risk factors, as well as increasing the availability of neuroimaging equipment.
文摘为推进有关医学科学、诊疗技术和公共卫生的历史研究,加强世界各国医学史研究人员和学会之间的交流,促进医学文化的交流与传播,国际医学史学会(International Society for the History of Medicine,ISHM)于1921年在巴黎宣布成立。利用ISHM的相关档案和口述访谈等辅助资料,还原其建立和演进的过程,并在全球政治和医学发展格局中,批判性地审视ISHM从以法国和比利时为主导,逐步走向欧洲大陆、欧洲和北美,最后走向全球,从以医生/医学史家为主体到融合科学技术史、生物医学史、医疗史和历史学家等多元学科的历史进程。
文摘荷兰莱顿世界博物馆(Leiden World Museum)收藏着18世纪70年代初荷兰海牙律师简·西奥多·罗也(Jean Theodore Royer)专门从广州订制和购买的,包括2000多幅绘画作品在内的人工制品,这批私人订制种类繁多,是当年日益繁荣的广州贸易的副产品,更是多重历史的产物。它既是18世纪西方世界罕见的关于遥远中国的知识研究型收集,反映了17—18世纪荷兰的科学发展和文化追求,尤其是罗也藏品中的绘画图册,作为18世纪中叶之后日益成熟的广州外销画作品,凸显出日益明显的外销画特点,是近代早期中西美术交流史上的重要作品;也是具有重要文化价值的历史记录。
