This paper sets up a mathematical model of switching network and switching function by utilizing graph theory to describe the logical function of different paths.The function varies with open and closed states of air ...This paper sets up a mathematical model of switching network and switching function by utilizing graph theory to describe the logical function of different paths.The function varies with open and closed states of air doors in a complex mine air sub network, and the computer program for solving the switching function of complex networks are offered. It gives the method for discriminating a reversible branch in a complex network by means of the switching function, and the method of counter inverted logical control of airflow inversion by means of open and short circuit conversion of key branches. The research has solved the problem of the stablization of air flow for normal ventination and reversing ventination in a diagonal network.展开更多
To enhance power flow regulation in scenarios involving large-scale renewable energy transmission via high-voltage direct current(HVDC)links and multi-infeed DC systems in load-center regions,this paper proposes a hyb...To enhance power flow regulation in scenarios involving large-scale renewable energy transmission via high-voltage direct current(HVDC)links and multi-infeed DC systems in load-center regions,this paper proposes a hybrid modular multilevel converter–capacitor-commutated line-commutated converter(MMC-CLCC)HVDC transmission system and its corresponding control strategy.First,the system topology is constructed,and a submodule configuration method for the MMC—combining full-bridge submodules(FBSMs)and half-bridge submodules(HBSMs)—is proposed to enable direct power flow reversal.Second,a hierarchical control strategy is introduced,includingMMCvoltage control,CLCC current control,and a coordinationmechanism,along with the derivation of the hybrid system’s power flow reversal characteristics.Third,leveraging the CLCC’s fast current regulation and theMMC’s negative voltage control capability,a coordinated power flow reversal control strategy is developed.Finally,an 800 kV MMC-CLCC hybrid HVDC system is modeled in PSCAD/EMTDC to validate the power flow reversal performance under a high proportion of full-bridge submodule configuration.Results demonstrate that the proposed control strategy enables rapid(1-s transition)and smooth switching of bidirectional power flow without modifying the structure of primary equipment:the transient fluctuation ofDC voltage from the rated value(UdcN)to themaximumreverse voltage(-kUdcN)is less than 5%;the DC current strictly follows the preset characteristic curve with a deviation of≤3%;the active power reverses continuously,and the system maintains stable operation throughout the reversal process.展开更多
The paper study the software and hardware principles of ultrasonic ranging reversing radar, design the vehicle reversing radar based on intelligent node of CAN bus, realize data communication and resource sharing with...The paper study the software and hardware principles of ultrasonic ranging reversing radar, design the vehicle reversing radar based on intelligent node of CAN bus, realize data communication and resource sharing with other intelligent nodes of the reversing radar. The experimental results show that, the design can achieve the expected technical indicators design, measurement precision and the reliability is high, which has certain guiding significance in the design of the car reversing radar, has wide application prospect and practical significance in the function of the extended CAN bus communication messages design and automotive CAN network.展开更多
As a hydrogen storage material,both AlH_(3)and LiNH_(2)possess a high hydrogen capacity.However,the dehydrogenated AlH_(3)can hardly absorb hydrogen under normal conditions,while LiNH_(2)will generate NH_(3)rather tha...As a hydrogen storage material,both AlH_(3)and LiNH_(2)possess a high hydrogen capacity.However,the dehydrogenated AlH_(3)can hardly absorb hydrogen under normal conditions,while LiNH_(2)will generate NH_(3)rather than H_(2)upon decomposition.In this work,we report thatthe combination of AlH_(3)and LiNH_(2)through simple ball milling leads to partial reversibility of the AlH_(3)-LiNH_(2)system and the suppression of NH_(3)liberation.The negatively charged H^(δ-)in AlH_(3)will react with the positively charged H^(δ+)in LiNH_(2)through a redox reaction to form Li_(2)NH,AlN,and H_(2)at 120-170℃.After dehydrogenation at above 270℃,Li_(3)AlN_(2)is generated,which is crucial for the reversibility of this system.The more the Li3AlN2generated,the better the reversibility of this system.The dehydrogenation capacity of AlH_(3)+2LiNH_(2)at the third cycle(3.0 wt%)is higher than that of AlH_(3)+LiNH_(2)(1.2 wt%)due to the generation of more Li3AlN2.The role of AIH_(3)/Al in the AlH_(3)-LiNH_(2)system is to fix the nitrogen into the form of AIN and Li_(3)AlN_(2)and thus suppress the liberation of NH_(3).Therefore,the synergy of AlH_(3)and LiNH_(2)leads to the reversibility of the Li-Al-NH system and the suppression of NH_(3).展开更多
BACKGROUND Posterior reversible encephalopathy syndrome(PRES)is a complex neurological disorder characterized by symptoms such as headaches,seizures,confusion,and visual disturbances.The pathophysiology of PRES involv...BACKGROUND Posterior reversible encephalopathy syndrome(PRES)is a complex neurological disorder characterized by symptoms such as headaches,seizures,confusion,and visual disturbances.The pathophysiology of PRES involves endothelial dysfunction,disrupted cerebral autoregulation,and resulting vasogenic edema.Hypertension and other factors that alter cerebral autoregulation are critical in its development.Corticosteroids,widely used for their anti-inflammatory and immunosuppressive properties,play a controversial role in PRES.AIM To elucidate the dual role of corticosteroids in the context of PRES by critically evaluating the existing literature.Specifically,it seeks to assess the results of PRES induced by corticosteroid therapy and the efficacy and safety of corticosteroids in the treatment of PRES.By synthesizing case reports and series,this review aims to provide a comprehensive understanding of the mechanisms,clinical presentations,and management strategies associated with corticosteroid-related PRES.METHODS The review was carried out according to the PRISMA guidelines.The databases searched included Science Direct,PubMed,and Hinari.The search strategy encompassed terms related to corticosteroids and PRES.Studies were included if they were peer-reviewed articles examining corticosteroids in PRES,excluding non-English publications,reviews,and editorials.Data on patient demographics,clinical characteristics,imaging findings,corticosteroid regimens,and outcomes were extracted.The risk of bias was evaluated using the Joanna Briggs Institute tool for case reports.RESULTS A total of 56 cases of PRES(66.1%women,33.9%men)potentially induced by corticosteroids and 14 cases in which corticosteroids were used to treat PRES were identified.Cases of PRES reportedly caused by corticosteroids showed a mean age of approximately 25.2 years,with seizures,headaches,hypertension,and visual disturbances being common clinical sequelae.Magnetic resonance findings typically revealed vasogenic edema in the bilateral parieto-occipital lobes.High-dose or prolonged corticosteroid therapy was a significant risk factor.On the contrary,in the treatment cases,corticosteroids were associated with positive outcomes,including resolution of vasogenic edema and stabilization of symptoms,particularly in patients with underlying inflammatory or autoimmune diseases.CONCLUSION Corticosteroids have a dual role in PRES,capable of both inducing and treating the condition.The current body of literature suggests that corticosteroids may play a greater role as a precipitating agent of PRES rather than treating.Corticosteroids may induce PRES through hypertension and subsequent increased cerebral blood flow and loss of autoregulation.Corticosteroids may aid in the management of PRES:(1)Enhancing endothelial stability;(2)Antiinflammatory properties;and(3)Improving blood-brain barrier integrity.Mechanisms which may reduce or mitigate vasogenic edema formation.展开更多
This study aims to enhance the maneuvering advantages of the waterjet unit through parametric design,performance evaluation,and optimization of the one-piece waterjet propulsion steering and reversing gear(SRG).The SR...This study aims to enhance the maneuvering advantages of the waterjet unit through parametric design,performance evaluation,and optimization of the one-piece waterjet propulsion steering and reversing gear(SRG).The SRG’s performance evaluation stems mainly from the effect of the free surface,the varying sailing speeds of the ship,and its performance while functioning at the stern of the waterjet-propelled vessel.Parameters such as the length,width,and height of the steering gear,as well as the inclination,width,and curvature of the reversing gear,significantly influence the SRG.Although the free surface has a great impact on the force of the SRG,its performance trend remains unaffected.When the SRG operates at the stern of the ship,the optimized scheme’s lateral force improves by an average of 8.08%for sailing with a rudder angle condition and an average of 45.69%for reversing sailing with a rudder angle condition.The longitudinal force of the optimized scheme improves by more than 23%when sailing without a rudder angle condition and by an average of 31.75%when sailing with a reversed rudder angle condition.Additionally,the speed of the rotor has a minimal effect on the lateral force and a significant effect on the longitudinal force.展开更多
Avian metapneumovirus(aMPV),a paramyxovirus,causes acute respiratory diseases in turkeys and swollen head syndrome in chickens.This study established a reverse genetics system for aMPV subtype B LN16-A strain based on...Avian metapneumovirus(aMPV),a paramyxovirus,causes acute respiratory diseases in turkeys and swollen head syndrome in chickens.This study established a reverse genetics system for aMPV subtype B LN16-A strain based on T7 RNA polymerase.Full-length cDNA of the LN16-A strain was constructed by assembling 5 cDNA fragments between the T7 promoter and hepatitis delta virus ribozyme.Transfection of this plasmid,along with the supporting plasmids encoding the N,P,M2-1,and L proteins of LN16-A into BSR-T7/5 cells,resulted in the recovery of aMPV subtype B.To identify an effective insertion site,the enhanced green fluorescent protein(EGFP)gene was inserted into different sites of the LN16-A genome to generate recombinant LN16-As.The results showed that the expression levels of EGFP at the site between the G and L genes of LN16-A were significantly higher than those at the other two sites(between the leader and N genes or replacing the SH gene).To verify the availability of the site between G and L for foreign gene expression,the VP2 gene of very virulent infectious bursal disease virus(vvIBDV)was inserted into this site,and recombinant LN16-A(rLN16A-vvVP2)was successfully rescued.Single immunization of specificpathogen-free chickens with rLN16A-vvVP2 induced high levels of neutralizing antibodies and provided 100%protection against the virulent aMPV subtype B and vvIBDV.Establishing a reverse genetics system here provides an important foundation for understanding aMPV pathogenesis and developing novel vector vaccines.展开更多
In high-speed multiuser Time Reversal(TR)downlink systems,the transmission rate is degraded due to the presence of severe inter-user and inter-symbol interference.Moreover,maximizing the weighted sum rate in such syst...In high-speed multiuser Time Reversal(TR)downlink systems,the transmission rate is degraded due to the presence of severe inter-user and inter-symbol interference.Moreover,maximizing the weighted sum rate in such systems is a critical objective,since the weighting factors represent the priority of different users in different applications.However,it faces significant challenges as it is an NP-hard and non-convex problem.In order to suppress these interferences and maximize the weighted sum rate,in this paper we present a novel approach for the joint design of the pre-filters.The proposed method applies successive convex approximation to transform the original problem into a Second-Order Cone Programming(SOCP)problem.Then,a low-complexity iterative algorithm is provided to effectively solve the resulting SOCP problem.According to the simulation results,the proposed method reaches a local optimum within a few iterations and demonstrates superior performance in terms of weighted sum rate compared to the current algorithm.展开更多
The excited state dynamics and critically regulated factors of reverse intersystem crossing(RISC)in through-space charge transfer(TSCT)molecules have received insufficient attention.Here,five molecules of through spac...The excited state dynamics and critically regulated factors of reverse intersystem crossing(RISC)in through-space charge transfer(TSCT)molecules have received insufficient attention.Here,five molecules of through space/bond charge transfer inducing thermally activated delayed fluorescence(TADF)are prepared,and their excited state charge transfer processes are studied by ultrafast transient absorption and theoretical calculations.DM-Z has a largerΔEST,leading to a longer lifetime of intersystem crossing(ISC),resulting in the lowest photoluminescence quantum yield(PLQY).Oppositely,ISC and RISC are demonstrated to take place with shorter lifetimes for TSCT molecules.The face-to-faceπ-πstacking interactions and electron communication enable DM-B and DM-BX to have an efficient RISC,increasing the weight coefficient of RISC from 1.7%(DM-X)to close to 50%(DM-B and DM-BX)in the solvents,which make DM-BX and DM-B to have a high PLQY.However,partial local excitation in the donor center is observed and the charge transfer is decreased for DM-G and DM-X.The triplet excited state(DM-G)or singlet excited state(DM-X)mainly undergoes inactivation through a non-radiative relaxation process,resulting in less RISC and low PLQY.This work provides theoretical hints to enhance the RISC process in the TADF materials.展开更多
The processing of measuri ng data plays an important role in reverse engineering. Based on grey system the ory, we first propose some methods to the processing of measuring data in revers e engineering. The measured d...The processing of measuri ng data plays an important role in reverse engineering. Based on grey system the ory, we first propose some methods to the processing of measuring data in revers e engineering. The measured data usually have some abnormalities. When the abnor mal data are eliminated by filtering, blanks are created. The grey generation an d GM(1,1) are used to create new data for these blanks. For the uneven data sequ en ce created by measuring error, the mean generation is used to smooth it and then the stepwise and smooth generations are used to improve the data sequence.展开更多
The ethanolic extracts of 100 common traditional Chinese drugs, which are widely used in many prescriptions in treatment of cancer in China, were screened for MDR of KBV200 cell line in vitro with MTT method. The ...The ethanolic extracts of 100 common traditional Chinese drugs, which are widely used in many prescriptions in treatment of cancer in China, were screened for MDR of KBV200 cell line in vitro with MTT method. The result showed 9 extracts having MDR reversal activity. They were the extracts of Fructus Lagenariae Sicerariae, Radix Glycyrrhizae, Poria, Herba Andrographitis, Radix Sophorae Tonkinensis, Caulis Mahoniae, Folium Artemisiae Argyi, Rhizoma Curcumae, Fructus Cnidii. Other 5 extracts showed cytotoxic on KBV200 cell line. $$$$展开更多
Filters,as a key component in the photoelectric detection system,can simplify the optical system and improve detection efficiency.Based on the usage requirements,a visible/near-infrared filter film with up to 5 waveba...Filters,as a key component in the photoelectric detection system,can simplify the optical system and improve detection efficiency.Based on the usage requirements,a visible/near-infrared filter film with up to 5 wavebands needs to be designed and prepared,while simultaneously satisfying high reflection in 2 wave-bands and high transmittance in 3 wavebands.Therefore,we have conducted a systematic study on the film design,thin film preparation process,and control accuracy of film layer thickness.In this work,the short-wave pass film system is superimposed with the long-wave pass film system,and the number of cycles and matching coefficient of the film system are tuned to meet the requirements of cut-off band.Additionally,Smith method was used to match bandpass film system to optimize the transmission band and complete the visible/near infrared multiband laser filter film design.In the preparation process,combined with the sensitiv-ity of the film layer,inverse analysis is used to invert the film layer monitored by each optical monitoring chip.The optical control scheme with weak optical signal in the monitoring process is simulated and correc-ted,and the monitoring wavelength with stronger optical signal is matched,resulting in an improvement of the control accuracy for the film thickness and the transmittance in the specified wavelength range.Ulti-mately,the actual physical thickness is 9.66μm,and the error with the theoretical design thickness is less than 0.4%,and the transmittance of the specified 3 wavebands exceeds 99%.The average transmittance of the cut-off bands at the 455−500 nm and 910−1000 nm is 0.45% and 0.16%,respectively.展开更多
By the iteration of the KAM, the following second- order differential equation （ Фp （x′））′ ＋ F（x, x′, t） ＋ ω^PФp （x′） ＋α│x│^l ＋e（x, t） =0 is studied, where Фp（S） = │S│^p-2s, p 〉 1, α〉 0...By the iteration of the KAM, the following second- order differential equation （ Фp （x′））′ ＋ F（x, x′, t） ＋ ω^PФp （x′） ＋α│x│^l ＋e（x, t） =0 is studied, where Фp（S） = │S│^p-2s, p 〉 1, α〉 0 and ω 〉 0 are positive constants, and l satisfies - 1 〈ω 〈p ＋ 2. Under some assumptions on the parities of F（x, x′, t） and e （x, t）, by a small twist theorem of reversible mapping, the existence of quasi-periodic solutions and boundedness of all the solutions are obtained.展开更多
The ethanolic extracts of 100 common traditional Chinese drugs, which are widely used in many prescriptions in treatment of cancer in China, were screened for MDR of KBV200 cell line in vitro with MTT method. The ...The ethanolic extracts of 100 common traditional Chinese drugs, which are widely used in many prescriptions in treatment of cancer in China, were screened for MDR of KBV200 cell line in vitro with MTT method. The result showed 9 extracts having MDR reversal activity. They were the extracts of Fructus Lagenariae Sicerariae, Radix Glycyrrhizae, Poria, Herba Andrographitis, Radix Sophorae Tonkinensis, Caulis Mahoniae, Folium Artemisiae Argyi, Rhizoma Curcumae, Fructus Cnidii. Other 5 extracts showed cytotoxic on KBV200 cell line. $$$$展开更多
Magnesium hydride(MgH_(2)) demonstrates immense potential as a solid-state hydrogen storage material,while its commercial utilization is impeded by the elevated operating temperature and sluggish reaction kinetics.Her...Magnesium hydride(MgH_(2)) demonstrates immense potential as a solid-state hydrogen storage material,while its commercial utilization is impeded by the elevated operating temperature and sluggish reaction kinetics.Herein,a MOF derived multi-phase FeNi_(3)-S catalyst was specially designed for efficient hydrogen storage in MgH_(2).Experiments confirmed that the incorporation of FeNi_(3)-S into MgH_(2) significantly lowered the desorption temperature and accelerated the kinetics of hydrogen desorption and reabsorption.The initial dehydrogenation temperature of the MgH_(2)+10 wt% FeNi_(3)-S composite was 202 ℃,which was 123 ℃ lower than that of pure MgH_(2).At 325 ℃,the MgH_(2)+10 wt% FeNi_(3)-S composite released 6.57 wt% H_(2)(fully dehydrogenated) within 1000 s.Remarkably,MgH_(2)+ 10 wt% FeNi_(3)-S composite initiated rehydrogenation at room temperature and rapidly absorbed 2.49 wt% H_(2) within 30 min at 100 ℃.Moreover,6.3 wt% H_(2) was still retained after 20 cycles at 300 ℃,demonstrating the superior cycling performance of the MgH_(2)+10 wt% FeNi_(3)-S composite.The activation energy fitting calculations further evidenced the addition of FeNi_(3)-S enhanced the de/resorption kinetics of MgH_(2)(E_(a)= 98.6 k J/mol and 43.3 k J/mol,respectively).Through phase and microstructural analysis,it was determined that the exceptional hydrogen storage performance of the composite was attributed to the in-situ formation of Mg/Mg_(2)Ni + Fe/MgS and MgH_(2)/Mg_(2)NiH_(4)+Fe/MgS hydrogen storage systems.Further mechanistic analysis revealed that Mg_(2)Ni/Mg_(2)NiH_(4) served as “hydrogen pump” and Fe/Mg S served as “hydrogen diffusion channel”,thus accelerating the dissociation and recombination of hydrogen molecules.In conclusion,this work offers insight into catalysts combining transition metal alloys and transition metal sulfide for exerting muti-phase synergistic effect on boosting the dehydrogenation/hydrogenation reactions of MgH_(2),which can also inspire future pioneering work on designing and fabricating high efficient catalysts in other energy storage related areas.展开更多
We propose an optimization method based on evolutionary computation for the design of broadband high-efficiency current-biased reverse load-modulation power amplifiers(CB-RLM PAs).First,given the reverse load-modulati...We propose an optimization method based on evolutionary computation for the design of broadband high-efficiency current-biased reverse load-modulation power amplifiers(CB-RLM PAs).First,given the reverse load-modulation characteristics of CB-RLM PAs,a comprehensive objective function is proposed that combines multi-state impedance trajectory constraints with in-band performance deviations.For the saturation and 6 dB power back-off(PBO)states,approximately optimal impedance regions on the Smith chart are derived using impedance constraint circles based on load-pull simulations.These regions are used together with in-band performance deviations(e.g.,saturated efficiency,6 dB PBO efficiency,and saturated output power)for matching network optimization and design.Second,a multi-objective evolutionary algorithm based on decomposition with adaptive weights,neighborhood,and global replacement is integrated with harmonic balance simulations to optimize design parameters and evaluate performance.Finally,to validate the proposed method,a broadband CB-RLM PA operating from 0.6 to 1.8 GHz is designed and fabricated.Measurement results show that the efficiencies at saturation,6 dB PBO,and 8 dB PBO all exceed 43.6%,with saturated output power being maintained at 40.9–41.5 dBm,which confirms the feasibility and effectiveness of the proposed broadband high-efficiency CB-RLM PA optimization and design approach.展开更多
The nervous system function requires a precise but plastic neural architecture.The neuronal shape dictates how neurons interact with each other and with other cells,being the morphology of dendrites and axons the cent...The nervous system function requires a precise but plastic neural architecture.The neuronal shape dictates how neurons interact with each other and with other cells,being the morphology of dendrites and axons the central determinant of the functional properties of neurons and neural circuits.The topological and structural morphology of axons and dendrites defines and determines how synapses are conformed.The morphological diversity of axon and dendrite arborization governs the neuron’s inputs,synaptic integration,neuronal computation,signal transmission,and network circuitry,hence defining the particular connectivity and function of the different brain areas.展开更多
Unwarranted death of neurons is a major cause of neurodegenerative diseases.Since mature neurons are postmitotic and do not replicate,their death usually constitutes an irreversible step in pathology.A logical strateg...Unwarranted death of neurons is a major cause of neurodegenerative diseases.Since mature neurons are postmitotic and do not replicate,their death usually constitutes an irreversible step in pathology.A logical strategy to prevent neurodegeneration would then be to save all neurons that are still alive,i.e.protecting the ones that are still healthy as well as trying to rescue the ones that are damaged and in the process of dying.Regarding the latter,recent experiments have indicated that the possibility of reversing the cell death process and rescuing dying cells is more significant than previously anticipated.In many situations,the elimination of the cell death trigger alone enables dying cells to spontaneously repair their damage,recover,and survive.In this review,we explore the factors,which determine the fate of neurons engaged in the cell death process.A deeper insight into cell death mechanisms and the intrinsic capacity of cells to recover could pave the way for novel therapeutic approaches to neurodegenerative diseases.展开更多
Conversion-type electrode materials hold significant promise for potassium-ion batteries(PIBs)due to their high theoretical capacities,yet their practical deployment is hindered by sluggish kinetics and irreversible s...Conversion-type electrode materials hold significant promise for potassium-ion batteries(PIBs)due to their high theoretical capacities,yet their practical deployment is hindered by sluggish kinetics and irreversible structural degradation.To overcome these limitations,we propose a rationally engineered nanoreactor architecture that stabilizes defect-rich MoS_(2)via interlayer incorporation of a carbon monolayer,followed by encapsulation within a nitrogen-doped carbon shell,forming a MoSSe@NC heterostructure.This tailored structure synergistically accelerates both K^(+)diffusion kinetics and electron transfer,enabling unprecedented rate performance(107 mAh g^(-1)at 10 Ag^(-1))and ultralong cyclability(86.5%capacity retention after 1200 cycles at 3 A g^(-1)).Mechanistic insights reveal a distinctive“adsorption-conversion”pathway,where sulfur vacancies on exposed S-Mo-S basal planes act as preferential K^(+)adsorption sites,effectively suppressing parasitic phase transitions during intercalation.In situ X-ray diffraction and transmission electron microscopy corroborate the structural reversibility of the conversion reaction,with the carbon matrix dynamically accommodating strain while preserving electrode integrity.This work not only advances the understanding of defect-driven interfacial chemistry in conversion-type materials but also provides a versatile strategy for designing high-performance anodes in next-generation PIBs through heterostructure engineering.展开更多
Message structure reconstruction is a critical task in protocol reverse engineering,aiming to recover protocol field structures without access to source code.It enables important applications in network security,inclu...Message structure reconstruction is a critical task in protocol reverse engineering,aiming to recover protocol field structures without access to source code.It enables important applications in network security,including malware analysis and protocol fuzzing.However,existing methods suffer from inaccurate field boundary delineation and lack hierarchical relationship recovery,resulting in imprecise and incomplete reconstructions.In this paper,we propose ProRE,a novel method for reconstructing protocol field structures based on program execution slice embedding.ProRE extracts code slices from protocol parsing at runtime,converts them into embedding vectors using a data flow-sensitive assembly language model,and performs hierarchical clustering to recover complete protocol field structures.Evaluation on two datasets containing 12 protocols shows that ProRE achieves an average F1 score of 0.85 and a cophenetic correlation coefficient of 0.189,improving by 19%and 0.126%respectively over state-of-the-art methods(including BinPRE,Tupni,Netlifter,and QwQ-32B-preview),demonstrating significant superiority in both accuracy and completeness of field structure recovery.Case studies further validate the effectiveness of ProRE in practical malware analysis scenarios.展开更多
文摘This paper sets up a mathematical model of switching network and switching function by utilizing graph theory to describe the logical function of different paths.The function varies with open and closed states of air doors in a complex mine air sub network, and the computer program for solving the switching function of complex networks are offered. It gives the method for discriminating a reversible branch in a complex network by means of the switching function, and the method of counter inverted logical control of airflow inversion by means of open and short circuit conversion of key branches. The research has solved the problem of the stablization of air flow for normal ventination and reversing ventination in a diagonal network.
基金supported by Science and Technology Project of the headquarters of the State Grid Corporation of China(No.5500-202324492A-3-2-ZN).
文摘To enhance power flow regulation in scenarios involving large-scale renewable energy transmission via high-voltage direct current(HVDC)links and multi-infeed DC systems in load-center regions,this paper proposes a hybrid modular multilevel converter–capacitor-commutated line-commutated converter(MMC-CLCC)HVDC transmission system and its corresponding control strategy.First,the system topology is constructed,and a submodule configuration method for the MMC—combining full-bridge submodules(FBSMs)and half-bridge submodules(HBSMs)—is proposed to enable direct power flow reversal.Second,a hierarchical control strategy is introduced,includingMMCvoltage control,CLCC current control,and a coordinationmechanism,along with the derivation of the hybrid system’s power flow reversal characteristics.Third,leveraging the CLCC’s fast current regulation and theMMC’s negative voltage control capability,a coordinated power flow reversal control strategy is developed.Finally,an 800 kV MMC-CLCC hybrid HVDC system is modeled in PSCAD/EMTDC to validate the power flow reversal performance under a high proportion of full-bridge submodule configuration.Results demonstrate that the proposed control strategy enables rapid(1-s transition)and smooth switching of bidirectional power flow without modifying the structure of primary equipment:the transient fluctuation ofDC voltage from the rated value(UdcN)to themaximumreverse voltage(-kUdcN)is less than 5%;the DC current strictly follows the preset characteristic curve with a deviation of≤3%;the active power reverses continuously,and the system maintains stable operation throughout the reversal process.
文摘The paper study the software and hardware principles of ultrasonic ranging reversing radar, design the vehicle reversing radar based on intelligent node of CAN bus, realize data communication and resource sharing with other intelligent nodes of the reversing radar. The experimental results show that, the design can achieve the expected technical indicators design, measurement precision and the reliability is high, which has certain guiding significance in the design of the car reversing radar, has wide application prospect and practical significance in the function of the extended CAN bus communication messages design and automotive CAN network.
基金financially supported by the National Natural Science Foundation of China(Nos.22379030,52001079,52261038)the Science and Technology Department of Guangxi Zhuang Autonomous(Nos.2024JJG160001,GuiKeAD21238022)the Innovation Project of Guangxi Graduate Education(No.YCBZ2023011)
文摘As a hydrogen storage material,both AlH_(3)and LiNH_(2)possess a high hydrogen capacity.However,the dehydrogenated AlH_(3)can hardly absorb hydrogen under normal conditions,while LiNH_(2)will generate NH_(3)rather than H_(2)upon decomposition.In this work,we report thatthe combination of AlH_(3)and LiNH_(2)through simple ball milling leads to partial reversibility of the AlH_(3)-LiNH_(2)system and the suppression of NH_(3)liberation.The negatively charged H^(δ-)in AlH_(3)will react with the positively charged H^(δ+)in LiNH_(2)through a redox reaction to form Li_(2)NH,AlN,and H_(2)at 120-170℃.After dehydrogenation at above 270℃,Li_(3)AlN_(2)is generated,which is crucial for the reversibility of this system.The more the Li3AlN2generated,the better the reversibility of this system.The dehydrogenation capacity of AlH_(3)+2LiNH_(2)at the third cycle(3.0 wt%)is higher than that of AlH_(3)+LiNH_(2)(1.2 wt%)due to the generation of more Li3AlN2.The role of AIH_(3)/Al in the AlH_(3)-LiNH_(2)system is to fix the nitrogen into the form of AIN and Li_(3)AlN_(2)and thus suppress the liberation of NH_(3).Therefore,the synergy of AlH_(3)and LiNH_(2)leads to the reversibility of the Li-Al-NH system and the suppression of NH_(3).
文摘BACKGROUND Posterior reversible encephalopathy syndrome(PRES)is a complex neurological disorder characterized by symptoms such as headaches,seizures,confusion,and visual disturbances.The pathophysiology of PRES involves endothelial dysfunction,disrupted cerebral autoregulation,and resulting vasogenic edema.Hypertension and other factors that alter cerebral autoregulation are critical in its development.Corticosteroids,widely used for their anti-inflammatory and immunosuppressive properties,play a controversial role in PRES.AIM To elucidate the dual role of corticosteroids in the context of PRES by critically evaluating the existing literature.Specifically,it seeks to assess the results of PRES induced by corticosteroid therapy and the efficacy and safety of corticosteroids in the treatment of PRES.By synthesizing case reports and series,this review aims to provide a comprehensive understanding of the mechanisms,clinical presentations,and management strategies associated with corticosteroid-related PRES.METHODS The review was carried out according to the PRISMA guidelines.The databases searched included Science Direct,PubMed,and Hinari.The search strategy encompassed terms related to corticosteroids and PRES.Studies were included if they were peer-reviewed articles examining corticosteroids in PRES,excluding non-English publications,reviews,and editorials.Data on patient demographics,clinical characteristics,imaging findings,corticosteroid regimens,and outcomes were extracted.The risk of bias was evaluated using the Joanna Briggs Institute tool for case reports.RESULTS A total of 56 cases of PRES(66.1%women,33.9%men)potentially induced by corticosteroids and 14 cases in which corticosteroids were used to treat PRES were identified.Cases of PRES reportedly caused by corticosteroids showed a mean age of approximately 25.2 years,with seizures,headaches,hypertension,and visual disturbances being common clinical sequelae.Magnetic resonance findings typically revealed vasogenic edema in the bilateral parieto-occipital lobes.High-dose or prolonged corticosteroid therapy was a significant risk factor.On the contrary,in the treatment cases,corticosteroids were associated with positive outcomes,including resolution of vasogenic edema and stabilization of symptoms,particularly in patients with underlying inflammatory or autoimmune diseases.CONCLUSION Corticosteroids have a dual role in PRES,capable of both inducing and treating the condition.The current body of literature suggests that corticosteroids may play a greater role as a precipitating agent of PRES rather than treating.Corticosteroids may induce PRES through hypertension and subsequent increased cerebral blood flow and loss of autoregulation.Corticosteroids may aid in the management of PRES:(1)Enhancing endothelial stability;(2)Antiinflammatory properties;and(3)Improving blood-brain barrier integrity.Mechanisms which may reduce or mitigate vasogenic edema formation.
基金supported by the Sanya Science and Education Innovation Park of Wuhan University of Technology(Grant No.2022KF0017)Hainan Provincial Natural Science Foundation of China(Grant No.522QN342)+1 种基金the National Natural Science Foundation of China(Grant No.52201376)Natural Science Foundation of Hubei Province,China(Grant No.2023AFB683).
文摘This study aims to enhance the maneuvering advantages of the waterjet unit through parametric design,performance evaluation,and optimization of the one-piece waterjet propulsion steering and reversing gear(SRG).The SRG’s performance evaluation stems mainly from the effect of the free surface,the varying sailing speeds of the ship,and its performance while functioning at the stern of the waterjet-propelled vessel.Parameters such as the length,width,and height of the steering gear,as well as the inclination,width,and curvature of the reversing gear,significantly influence the SRG.Although the free surface has a great impact on the force of the SRG,its performance trend remains unaffected.When the SRG operates at the stern of the ship,the optimized scheme’s lateral force improves by an average of 8.08%for sailing with a rudder angle condition and an average of 45.69%for reversing sailing with a rudder angle condition.The longitudinal force of the optimized scheme improves by more than 23%when sailing without a rudder angle condition and by an average of 31.75%when sailing with a reversed rudder angle condition.Additionally,the speed of the rotor has a minimal effect on the lateral force and a significant effect on the longitudinal force.
基金supported by the grants from the National Key Research and Development Program of China(2022YFD1800604)the China Agriculture Research System(CARS-41)the Heilongjiang Touyan Innovation Team Program,China。
文摘Avian metapneumovirus(aMPV),a paramyxovirus,causes acute respiratory diseases in turkeys and swollen head syndrome in chickens.This study established a reverse genetics system for aMPV subtype B LN16-A strain based on T7 RNA polymerase.Full-length cDNA of the LN16-A strain was constructed by assembling 5 cDNA fragments between the T7 promoter and hepatitis delta virus ribozyme.Transfection of this plasmid,along with the supporting plasmids encoding the N,P,M2-1,and L proteins of LN16-A into BSR-T7/5 cells,resulted in the recovery of aMPV subtype B.To identify an effective insertion site,the enhanced green fluorescent protein(EGFP)gene was inserted into different sites of the LN16-A genome to generate recombinant LN16-As.The results showed that the expression levels of EGFP at the site between the G and L genes of LN16-A were significantly higher than those at the other two sites(between the leader and N genes or replacing the SH gene).To verify the availability of the site between G and L for foreign gene expression,the VP2 gene of very virulent infectious bursal disease virus(vvIBDV)was inserted into this site,and recombinant LN16-A(rLN16A-vvVP2)was successfully rescued.Single immunization of specificpathogen-free chickens with rLN16A-vvVP2 induced high levels of neutralizing antibodies and provided 100%protection against the virulent aMPV subtype B and vvIBDV.Establishing a reverse genetics system here provides an important foundation for understanding aMPV pathogenesis and developing novel vector vaccines.
基金partially supported by the following funding sources:The National Natural Science Foundation of China(No.61771084)the Chongqing Graduate Scientific Research Innovation Project(No.CYB21200)。
文摘In high-speed multiuser Time Reversal(TR)downlink systems,the transmission rate is degraded due to the presence of severe inter-user and inter-symbol interference.Moreover,maximizing the weighted sum rate in such systems is a critical objective,since the weighting factors represent the priority of different users in different applications.However,it faces significant challenges as it is an NP-hard and non-convex problem.In order to suppress these interferences and maximize the weighted sum rate,in this paper we present a novel approach for the joint design of the pre-filters.The proposed method applies successive convex approximation to transform the original problem into a Second-Order Cone Programming(SOCP)problem.Then,a low-complexity iterative algorithm is provided to effectively solve the resulting SOCP problem.According to the simulation results,the proposed method reaches a local optimum within a few iterations and demonstrates superior performance in terms of weighted sum rate compared to the current algorithm.
基金supported by the National Natural Science Foundation of China(No.22273057)the Universities Joint Laboratory of Guangdong,Hong Kong and Macao(No.2021LSYS009)+2 种基金the Natural Science Foundation of Guangdong Province(Nos.2022A1515011661,2023A1515012631)the Chemistry and Chemical Engineering Guangdong Laboratory(No.1922003)Guangdong Major Project of Basic and Applied Basic Research(No.2019B030302009)。
文摘The excited state dynamics and critically regulated factors of reverse intersystem crossing(RISC)in through-space charge transfer(TSCT)molecules have received insufficient attention.Here,five molecules of through space/bond charge transfer inducing thermally activated delayed fluorescence(TADF)are prepared,and their excited state charge transfer processes are studied by ultrafast transient absorption and theoretical calculations.DM-Z has a largerΔEST,leading to a longer lifetime of intersystem crossing(ISC),resulting in the lowest photoluminescence quantum yield(PLQY).Oppositely,ISC and RISC are demonstrated to take place with shorter lifetimes for TSCT molecules.The face-to-faceπ-πstacking interactions and electron communication enable DM-B and DM-BX to have an efficient RISC,increasing the weight coefficient of RISC from 1.7%(DM-X)to close to 50%(DM-B and DM-BX)in the solvents,which make DM-BX and DM-B to have a high PLQY.However,partial local excitation in the donor center is observed and the charge transfer is decreased for DM-G and DM-X.The triplet excited state(DM-G)or singlet excited state(DM-X)mainly undergoes inactivation through a non-radiative relaxation process,resulting in less RISC and low PLQY.This work provides theoretical hints to enhance the RISC process in the TADF materials.
文摘The processing of measuri ng data plays an important role in reverse engineering. Based on grey system the ory, we first propose some methods to the processing of measuring data in revers e engineering. The measured data usually have some abnormalities. When the abnor mal data are eliminated by filtering, blanks are created. The grey generation an d GM(1,1) are used to create new data for these blanks. For the uneven data sequ en ce created by measuring error, the mean generation is used to smooth it and then the stepwise and smooth generations are used to improve the data sequence.
基金support of National Natural Science Foundation of China(39970892)
文摘The ethanolic extracts of 100 common traditional Chinese drugs, which are widely used in many prescriptions in treatment of cancer in China, were screened for MDR of KBV200 cell line in vitro with MTT method. The result showed 9 extracts having MDR reversal activity. They were the extracts of Fructus Lagenariae Sicerariae, Radix Glycyrrhizae, Poria, Herba Andrographitis, Radix Sophorae Tonkinensis, Caulis Mahoniae, Folium Artemisiae Argyi, Rhizoma Curcumae, Fructus Cnidii. Other 5 extracts showed cytotoxic on KBV200 cell line. $$$$
文摘Filters,as a key component in the photoelectric detection system,can simplify the optical system and improve detection efficiency.Based on the usage requirements,a visible/near-infrared filter film with up to 5 wavebands needs to be designed and prepared,while simultaneously satisfying high reflection in 2 wave-bands and high transmittance in 3 wavebands.Therefore,we have conducted a systematic study on the film design,thin film preparation process,and control accuracy of film layer thickness.In this work,the short-wave pass film system is superimposed with the long-wave pass film system,and the number of cycles and matching coefficient of the film system are tuned to meet the requirements of cut-off band.Additionally,Smith method was used to match bandpass film system to optimize the transmission band and complete the visible/near infrared multiband laser filter film design.In the preparation process,combined with the sensitiv-ity of the film layer,inverse analysis is used to invert the film layer monitored by each optical monitoring chip.The optical control scheme with weak optical signal in the monitoring process is simulated and correc-ted,and the monitoring wavelength with stronger optical signal is matched,resulting in an improvement of the control accuracy for the film thickness and the transmittance in the specified wavelength range.Ulti-mately,the actual physical thickness is 9.66μm,and the error with the theoretical design thickness is less than 0.4%,and the transmittance of the specified 3 wavebands exceeds 99%.The average transmittance of the cut-off bands at the 455−500 nm and 910−1000 nm is 0.45% and 0.16%,respectively.
基金The National Natural Science Foundation of China(No. 11071038)the Natural Science Foundation of Jiangsu Province(No. BK2010420)
文摘By the iteration of the KAM, the following second- order differential equation （ Фp （x′））′ ＋ F（x, x′, t） ＋ ω^PФp （x′） ＋α│x│^l ＋e（x, t） =0 is studied, where Фp（S） = │S│^p-2s, p 〉 1, α〉 0 and ω 〉 0 are positive constants, and l satisfies - 1 〈ω 〈p ＋ 2. Under some assumptions on the parities of F（x, x′, t） and e （x, t）, by a small twist theorem of reversible mapping, the existence of quasi-periodic solutions and boundedness of all the solutions are obtained.
文摘The ethanolic extracts of 100 common traditional Chinese drugs, which are widely used in many prescriptions in treatment of cancer in China, were screened for MDR of KBV200 cell line in vitro with MTT method. The result showed 9 extracts having MDR reversal activity. They were the extracts of Fructus Lagenariae Sicerariae, Radix Glycyrrhizae, Poria, Herba Andrographitis, Radix Sophorae Tonkinensis, Caulis Mahoniae, Folium Artemisiae Argyi, Rhizoma Curcumae, Fructus Cnidii. Other 5 extracts showed cytotoxic on KBV200 cell line. $$$$
基金supported by the National Key R&D Program of China (No.2022YFB3803703)the National Natural Science Foundation of China (Nos.52071141,52271212,52201250,51771056,22305104)+1 种基金the Natural Science Foundation of Jiangsu Province (No.BK20210893)the Ministry of Science and Technology of the People’s Republic of China (No.G2023014022L)。
文摘Magnesium hydride(MgH_(2)) demonstrates immense potential as a solid-state hydrogen storage material,while its commercial utilization is impeded by the elevated operating temperature and sluggish reaction kinetics.Herein,a MOF derived multi-phase FeNi_(3)-S catalyst was specially designed for efficient hydrogen storage in MgH_(2).Experiments confirmed that the incorporation of FeNi_(3)-S into MgH_(2) significantly lowered the desorption temperature and accelerated the kinetics of hydrogen desorption and reabsorption.The initial dehydrogenation temperature of the MgH_(2)+10 wt% FeNi_(3)-S composite was 202 ℃,which was 123 ℃ lower than that of pure MgH_(2).At 325 ℃,the MgH_(2)+10 wt% FeNi_(3)-S composite released 6.57 wt% H_(2)(fully dehydrogenated) within 1000 s.Remarkably,MgH_(2)+ 10 wt% FeNi_(3)-S composite initiated rehydrogenation at room temperature and rapidly absorbed 2.49 wt% H_(2) within 30 min at 100 ℃.Moreover,6.3 wt% H_(2) was still retained after 20 cycles at 300 ℃,demonstrating the superior cycling performance of the MgH_(2)+10 wt% FeNi_(3)-S composite.The activation energy fitting calculations further evidenced the addition of FeNi_(3)-S enhanced the de/resorption kinetics of MgH_(2)(E_(a)= 98.6 k J/mol and 43.3 k J/mol,respectively).Through phase and microstructural analysis,it was determined that the exceptional hydrogen storage performance of the composite was attributed to the in-situ formation of Mg/Mg_(2)Ni + Fe/MgS and MgH_(2)/Mg_(2)NiH_(4)+Fe/MgS hydrogen storage systems.Further mechanistic analysis revealed that Mg_(2)Ni/Mg_(2)NiH_(4) served as “hydrogen pump” and Fe/Mg S served as “hydrogen diffusion channel”,thus accelerating the dissociation and recombination of hydrogen molecules.In conclusion,this work offers insight into catalysts combining transition metal alloys and transition metal sulfide for exerting muti-phase synergistic effect on boosting the dehydrogenation/hydrogenation reactions of MgH_(2),which can also inspire future pioneering work on designing and fabricating high efficient catalysts in other energy storage related areas.
基金supported by the National Natural Science Foundation of China(Nos.62171204,62171129,62001192).
文摘We propose an optimization method based on evolutionary computation for the design of broadband high-efficiency current-biased reverse load-modulation power amplifiers(CB-RLM PAs).First,given the reverse load-modulation characteristics of CB-RLM PAs,a comprehensive objective function is proposed that combines multi-state impedance trajectory constraints with in-band performance deviations.For the saturation and 6 dB power back-off(PBO)states,approximately optimal impedance regions on the Smith chart are derived using impedance constraint circles based on load-pull simulations.These regions are used together with in-band performance deviations(e.g.,saturated efficiency,6 dB PBO efficiency,and saturated output power)for matching network optimization and design.Second,a multi-objective evolutionary algorithm based on decomposition with adaptive weights,neighborhood,and global replacement is integrated with harmonic balance simulations to optimize design parameters and evaluate performance.Finally,to validate the proposed method,a broadband CB-RLM PA operating from 0.6 to 1.8 GHz is designed and fabricated.Measurement results show that the efficiencies at saturation,6 dB PBO,and 8 dB PBO all exceed 43.6%,with saturated output power being maintained at 40.9–41.5 dBm,which confirms the feasibility and effectiveness of the proposed broadband high-efficiency CB-RLM PA optimization and design approach.
基金supported by the Wellcome Trust(grant No.103852).
文摘The nervous system function requires a precise but plastic neural architecture.The neuronal shape dictates how neurons interact with each other and with other cells,being the morphology of dendrites and axons the central determinant of the functional properties of neurons and neural circuits.The topological and structural morphology of axons and dendrites defines and determines how synapses are conformed.The morphological diversity of axon and dendrite arborization governs the neuron’s inputs,synaptic integration,neuronal computation,signal transmission,and network circuitry,hence defining the particular connectivity and function of the different brain areas.
基金supported by the following foundations:“Stichting Oogfonds Nederland(No.2023-26)”the“Landelijke Stichting voor Blinden en Slechtzienden(No.2023-24)”that contributed through UitZicht,ZonMw grant(No.435005020)a grant of the Chinese Scholarship Council(No.201809110169)(to TGMFG,CPMR,and WY).
文摘Unwarranted death of neurons is a major cause of neurodegenerative diseases.Since mature neurons are postmitotic and do not replicate,their death usually constitutes an irreversible step in pathology.A logical strategy to prevent neurodegeneration would then be to save all neurons that are still alive,i.e.protecting the ones that are still healthy as well as trying to rescue the ones that are damaged and in the process of dying.Regarding the latter,recent experiments have indicated that the possibility of reversing the cell death process and rescuing dying cells is more significant than previously anticipated.In many situations,the elimination of the cell death trigger alone enables dying cells to spontaneously repair their damage,recover,and survive.In this review,we explore the factors,which determine the fate of neurons engaged in the cell death process.A deeper insight into cell death mechanisms and the intrinsic capacity of cells to recover could pave the way for novel therapeutic approaches to neurodegenerative diseases.
基金financially supported by the supported by Shandong Provincial Natural Science Foundation(ZR2024MB108)Taishan Young Scholar Program(tsqn202312312)Excellent Young Scholars of the Shandong Provincial Natural Science Foundation(Overseas)(2023HWYQ-112)。
文摘Conversion-type electrode materials hold significant promise for potassium-ion batteries(PIBs)due to their high theoretical capacities,yet their practical deployment is hindered by sluggish kinetics and irreversible structural degradation.To overcome these limitations,we propose a rationally engineered nanoreactor architecture that stabilizes defect-rich MoS_(2)via interlayer incorporation of a carbon monolayer,followed by encapsulation within a nitrogen-doped carbon shell,forming a MoSSe@NC heterostructure.This tailored structure synergistically accelerates both K^(+)diffusion kinetics and electron transfer,enabling unprecedented rate performance(107 mAh g^(-1)at 10 Ag^(-1))and ultralong cyclability(86.5%capacity retention after 1200 cycles at 3 A g^(-1)).Mechanistic insights reveal a distinctive“adsorption-conversion”pathway,where sulfur vacancies on exposed S-Mo-S basal planes act as preferential K^(+)adsorption sites,effectively suppressing parasitic phase transitions during intercalation.In situ X-ray diffraction and transmission electron microscopy corroborate the structural reversibility of the conversion reaction,with the carbon matrix dynamically accommodating strain while preserving electrode integrity.This work not only advances the understanding of defect-driven interfacial chemistry in conversion-type materials but also provides a versatile strategy for designing high-performance anodes in next-generation PIBs through heterostructure engineering.
文摘Message structure reconstruction is a critical task in protocol reverse engineering,aiming to recover protocol field structures without access to source code.It enables important applications in network security,including malware analysis and protocol fuzzing.However,existing methods suffer from inaccurate field boundary delineation and lack hierarchical relationship recovery,resulting in imprecise and incomplete reconstructions.In this paper,we propose ProRE,a novel method for reconstructing protocol field structures based on program execution slice embedding.ProRE extracts code slices from protocol parsing at runtime,converts them into embedding vectors using a data flow-sensitive assembly language model,and performs hierarchical clustering to recover complete protocol field structures.Evaluation on two datasets containing 12 protocols shows that ProRE achieves an average F1 score of 0.85 and a cophenetic correlation coefficient of 0.189,improving by 19%and 0.126%respectively over state-of-the-art methods(including BinPRE,Tupni,Netlifter,and QwQ-32B-preview),demonstrating significant superiority in both accuracy and completeness of field structure recovery.Case studies further validate the effectiveness of ProRE in practical malware analysis scenarios.
