The objective of this study was to construct the infectious clone of encephalomyocarditis virus (EMCV) BJC3 strain.The genomic cDNA of the virus was amplified by three overlapping segments using RT-PCR,and cloned into...The objective of this study was to construct the infectious clone of encephalomyocarditis virus (EMCV) BJC3 strain.The genomic cDNA of the virus was amplified by three overlapping segments using RT-PCR,and cloned into low-copy plasmid pWSK29 to construct the full-length cDNA clone pWSKBJC3/ w.The pWSKBJC3/w was in vitro transcribed and transfected into BHK-21 cells to rescue the virus.The results showed that the full-length cDNA clone was infectious and the virus could be rescued in BHK-21 cells.The rescued virus designated RvBJC3W was identified by RT-PCR and indirect immunofluorescence assay(IFA).The rescued virus had similar growth characteristics to its parental virus BJC3 and retained pathogenicity for mice.Our results indicate that the first infectious cDNA clone of EMCV in China has been successfully established and provides an essential tool for investigating the molecular basis of pathogenicity of EMCV.展开更多
1 On April 12,a group of campers in a California forest heard a crying noise.They discovered a small black bear cub that was all alone.The California Department of Fish and Wildlife kept an eye on the cub.When the mot...1 On April 12,a group of campers in a California forest heard a crying noise.They discovered a small black bear cub that was all alone.The California Department of Fish and Wildlife kept an eye on the cub.When the mother didnt return,they took the bear to the Ramona Wildlife Center,which is run by the San Diego Humane Society.The center specializes in helping wild animals.展开更多
ON May 20,2025,eighteen descendants of British prisoners of war(POWs)rescued in the Lisbon Maru incident arrived on Dongji Island in east China’s Zhejiang Province,after a long transoceanic journey.They joined descen...ON May 20,2025,eighteen descendants of British prisoners of war(POWs)rescued in the Lisbon Maru incident arrived on Dongji Island in east China’s Zhejiang Province,after a long transoceanic journey.They joined descendants of the local fishermen who had saved their ancestors 83 years ago,gathering to witness the unveiling of a memorial erected in honor of the fishermen’s extraordinary bravery.At its center,the memorial bears the inscription:“Love knows no boundaries;Friendship transcends time.”展开更多
1 On December 26,2024,a remarkable act of heroism took place at Poospatuck Creek.Kayla Masotto,a 28⁃year⁃old resident of Mastic,Long Island,stepped into the role of a life⁃saver when she witnessed a man fall through t...1 On December 26,2024,a remarkable act of heroism took place at Poospatuck Creek.Kayla Masotto,a 28⁃year⁃old resident of Mastic,Long Island,stepped into the role of a life⁃saver when she witnessed a man fall through the ice on the lake.2 At about 6 pm,Kayla was washing vegetables in the kitchen when her attention was suddenly caught by a boy skating alone on the lake.In a split second,she witnessed the ice beneath him break,and the boy fell into the water.Without any hesitation,Kayla immediately grabbed her paddleboard(桨叶式冲浪板)and ran across her backyard,reaching the edge of the lake in seconds.展开更多
Charlie,a father from Sunderland,was enjoying a meal with friends when sudden panic erupted at a nearby table.A woman began to choke,her face turning red as her breaths became shallow.Her friend wildly pounded her bac...Charlie,a father from Sunderland,was enjoying a meal with friends when sudden panic erupted at a nearby table.A woman began to choke,her face turning red as her breaths became shallow.Her friend wildly pounded her back,and others yelled for help.Without hesitation,Charlie sprang into action.展开更多
The existing research on rescue robots has focused mainly on reconnaissance,detection,and firefighting,and a small number of robots that can achieve human rescue have problems such as poor safety and stability and ins...The existing research on rescue robots has focused mainly on reconnaissance,detection,and firefighting,and a small number of robots that can achieve human rescue have problems such as poor safety and stability and insufficient carrying capacity.This article addresses the above issues and cleverly combines the advantages of soft robotic arms,underactuated robotic arms,and suction cups based on the principles of bionics.A new design for a robotic arm was proposed,and its working principle was explained.Then,the human rescue process was divided into two stages,and the grasping force of the robotic arm in each stage was analyzed separately.Finally,a prototype of the principle was developed,and the feasibility of the design principle of the robotic arm was verified through grasping experiments on a cross-sectional contour model of the human chest.At the same time,grasping experiments were conducted on different objects to demonstrate the potential application of the robotic arm in grasping ground objects.This research proposes a stress envelope adsorption rescue robot arm inspired by the adhesion ability of the Drosera plant and the stress envelope effect,which can apply force to the entire surface of the human body,reduce local force on the human body,ensure load-bearing capacity and adaptability,and improve the safety and stability of rescue grasping.展开更多
Researchers have discovered that mice instinctively exhibit rescue-like behavior towards anesthetized companions-a finding that suggests a biological basis for prosociality.The study,published in PNAS on April 23,2025...Researchers have discovered that mice instinctively exhibit rescue-like behavior towards anesthetized companions-a finding that suggests a biological basis for prosociality.The study,published in PNAS on April 23,2025,was led by Dr.HU Li from the Institute of Psychology of the Chinese Academy of Sciences(IPCAS)and Dr.CHEN Zhoufeng from Washington University School of Medicine and the Shenzhen Medical Academy of Research and Translation.展开更多
A devastating disease called Huanglongbing(HLB) or citrus green is wiping out citrus trees across the globe. But we are seeing new hope. Scientists have recently uncovered a hidden battle happening inside citrus plant...A devastating disease called Huanglongbing(HLB) or citrus green is wiping out citrus trees across the globe. But we are seeing new hope. Scientists have recently uncovered a hidden battle happening inside citrus plants. Understanding this microscopic tug-of-war could be the key to rescuing our beloved oranges, lemons, and grapefruits.展开更多
1 The grandfather was choking on a mouthful of food,unable to breathe and unable to cough.The grandson,recalling the important lesson learned during the 8-13 Project organized by the Italian Red Cross⁃Poggi⁃Sermide Co...1 The grandfather was choking on a mouthful of food,unable to breathe and unable to cough.The grandson,recalling the important lesson learned during the 8-13 Project organized by the Italian Red Cross⁃Poggi⁃Sermide Committee,suggested performing the Heimlich manoeuvre(海姆立克急救法)on the elderly man.展开更多
Objective:To explore the application effect of emergency rescue capability intervention among students in a university in Beijing.Methods:A total of 900 students from a university in Beijing in 2023 were selected as t...Objective:To explore the application effect of emergency rescue capability intervention among students in a university in Beijing.Methods:A total of 900 students from a university in Beijing in 2023 were selected as the research objects.Emergency rescue capability training was conducted from March 2023 to June 2023,once a month.The students’mastery of emergency rescue before and after the intervention was analyzed.Survey questionnaires were distributed to all college students to understand their channels and willingness to acquire emergency rescue knowledge.Results:A total of 886 valid questionnaires were collected in this study.The highest proportion of knowledge about China’s general emergency telephone number and how to dial the emergency rescue hotline was 100.00%.Among the strategies for dealing with cardiac arrest in CPR,the highest proportion was 336.34%.Among the four major first aid techniques of hemostasis,bandaging,fixation,transportation,the highest proportion of knowledge about the use of rubber band signs was 31.71%.Among the first aid techniques for heatstroke,poisoning,fire,and sharp instrument injuries,the principle of emergency treatment for severe gas poisoning had the highest proportion of 41.42%,showing significant differences.College students mainly acquire knowledge of emergency rescue capability through TV programs,health education lectures,and the internet.Around 61.40%of college students hope to learn more about prevention and control knowledge.Conclusion:After the intervention of emergency rescue capability,the emergency rescue capability of college students in this university has been significantly improved,showing a strong training effect,which is worthy of promotion.展开更多
High-altitude rescue is dangerous and difficult.A new rescue method is proposed here based on electromagnetically launched tethered nets.Four electromagnetic launching units are attached to a revolving platform,from w...High-altitude rescue is dangerous and difficult.A new rescue method is proposed here based on electromagnetically launched tethered nets.Four electromagnetic launching units are attached to a revolving platform,from which four projectiles are launched.The four projectiles are connected to a tethered net,bringing it into motion.As the tethered net approaches and comes into contact with the object,the object will be trapped,and the rescue task will then be completed as long as the tethered net can be restored along with the trapped object.The structural design of the electromagnetic launching unit is presented with the established mathematical model.The motion characteristics of the launched projectiles are studied and their exit velocities are modeled and measured.Terminal velocities of these projectiles are characterized,and the final shape and position of the projected tethered net are obtained.This study validates the feasibility of using electromagnetically launched tethered nets to perform high-altitude rescues.展开更多
Unlike other major crops,little research has been performed on tomato to reduce the generation time for speed breeding.We evaluated several agronomic treatments to reduce the generation time of tomato in the‘M82'...Unlike other major crops,little research has been performed on tomato to reduce the generation time for speed breeding.We evaluated several agronomic treatments to reduce the generation time of tomato in the‘M82'(determinate)and‘Moneymaker'(indeterminate)varieties and evaluated the best combination in conjunction with embryo rescue.Five container sizes with volumes of 0.2 L(XS),0.45 L(S),0.8 L(M),1.3 L(L),and6 L(XL),were evaluated in the first experiment under the autumn cycle.We found that plants grown in XL containers exhibited better development and required less time from sowing to anthesis(DSA)and from anthesis to fruit ripening(DAR).In the second experiment,using XL containers in the autumn-winter cycle,we evaluated the effects of cold priming at the cotyledonary stage,water stress,P supplementation,and K supplementation on generation time.Compared to the control,we found that cold priming significantly reduced the number of leaves,plant height to first the inflorescence,and DSA(2.7 d),whereas K supplementation reduced the DAR(8.8 d).In contrast,water stress and P supplementation did not significantly affect any of the measured traits like DAR,DSA or fruit set.To validate these data,in a third experiment with XL containers in the spring-summer cycle,the combination of cold priming and K supplementation was tested,confirming the significant effect of this combination on the reduction of generation time(2.9 d for DSA and 3.9 d for DAR)compared to the control.Embryo rescue during the cell expansion cycle(average of 22.0 d and 23.3 d after anthesis for‘M82'and‘Moneymaker',respectively)allowed the shortening of the generation time by 8.7 d in‘M82'and 11.6 d in‘Moneymaker'compared to the in planta fruit ripening.The combination of agronomic treatments with embryo rescue can effectively increase the number of generations per year from three to four for speed breeding of tomato.展开更多
The ability of cyborg locusts to achieve directional movement in complex outdoor environments is critical for search and rescue missions.Currently,there is a lack of research on motion control for cyborg locusts in ou...The ability of cyborg locusts to achieve directional movement in complex outdoor environments is critical for search and rescue missions.Currently,there is a lack of research on motion control for cyborg locusts in outdoor settings.In this study,we developed cyborg locusts capable of performing directional locomotion in intricate outdoor environments,including jumping over obstacles,climbing slopes,traversing narrow pipelines,and accurately reaching predetermined targets along specified routes.We designed a miniature electrical backpack(10 mm×10 mm,0.75 g)capable of receiving stimulus parameters(frequency,duty ratio,and stimulation time)via Bluetooth commands from mobile phones.Electrical stimulation of locust sensory organs,such as the antennae and cercus,induced turning and jumping behaviors.Experi-mental testing of locust movement control was conducted under outdoor conditions with a short electrical stimulation interval.Results showed a positive correlation between locust turning angles and electrical stimulation parameters within a specified range,with an average jumping height exceeding 10 cm.Additionally,the success rate of locust turning and jumping behaviors correlated positively with the interval time between electrical stimulations.Adjusting these intervals during forward crawling phases increased the likelihood of the locusts jumping again.In conclusion,this study success-fully achieved directional locomotion control of cyborg locusts outdoors,providing insights and references for advancing search and rescue capabilities.展开更多
1.Opportunities for electric motor drives in the low-altitude economy The implementation plan for the innovative application of general aviation equipment(2024–2030)outlines that by 2027,new general aviation equipmen...1.Opportunities for electric motor drives in the low-altitude economy The implementation plan for the innovative application of general aviation equipment(2024–2030)outlines that by 2027,new general aviation equipment will achieve commercial applications in urban air transport,logistics distribution and emergency rescue.展开更多
Objective: To analyze the clinical significance of the emergency green channel in the treatment of patients with acute chest pain. Methods: Sixty patients with acute chest pain treated between September 2022 and July ...Objective: To analyze the clinical significance of the emergency green channel in the treatment of patients with acute chest pain. Methods: Sixty patients with acute chest pain treated between September 2022 and July 2024 were selected as the subjects of this study. They were divided into groups based on the order of treatment: the first 30 patients were included in the Green Channel group, where the emergency green channel was employed, while the remaining 30 patients were placed in the Regular Emergency group, receiving standard emergency treatment. The rescue time, hospitalization time, pain scores, incidence of adverse reactions, and quality of life between the Green Channel group and the Regular Emergency group were compared. Results: The rescue time and hospitalization time of the Green Channel group were shorter than those of the Regular Emergency group, with statistical significance (P < 0.05). The pain scores at 30, 60, 120, and 240 minutes after rescue in the Green Channel group were lower than those in the Regular Emergency group, with statistical significance (P < 0.05). The incidence of adverse reactions such as recurrent acute attacks, arrhythmia, heart failure, stroke, and shock in the Green Channel group was lower than that in the Regular Emergency group, with statistical significance (P < 0.05). The treatment satisfaction rate and success rate in the Green Channel group were 93.33% and 93.33%, respectively, while those in the Regular Emergency group were 73.33% and 73.33%. Both the satisfaction and success rates in the Green Channel group were higher than those in the Regular Emergency group, with statistical significance (P < 0.05). The quality of life in the Green Channel group was also higher than that in the Regular Emergency group, with statistical significance (P < 0.05). Conclusion: The emergency green channel plays a significant role in the treatment of patients with acute chest pain and is worthy of widespread clinical application.展开更多
In recent years,with the increasing frequency of global Marine activities,the occurrence probability of Marine accidents and emergencies has also increased.As a new technical means,small unmanned aerial vehicles(UAVs)...In recent years,with the increasing frequency of global Marine activities,the occurrence probability of Marine accidents and emergencies has also increased.As a new technical means,small unmanned aerial vehicles(UAVs)have shown great application potential in Marine search and rescue activities.In Marine search and rescue activities,small UAVs can quickly arrive at the scene of the accident and carry out efficient information collection and monitoring under its simple and flexible operation.Compared with traditional search and rescue methods,small UAVs can cover a wider area,provide more detailed and accurate on-site information,provide strong support for search and rescue decision-making,and thus improve the quality and efficiency of maritime rescue.In this regard,this paper first describes the application advantages of small UAVs in Marine search and rescue activities and then puts forward effective application paths,to provide some references for relevant researchers.展开更多
The year 2025 marks the 80th anniversary of the victory in the Chinese People’s War of Resistance Against Japanese Aggression and the World Anti-Fascist War.During World War II,China forged profound bonds with nation...The year 2025 marks the 80th anniversary of the victory in the Chinese People’s War of Resistance Against Japanese Aggression and the World Anti-Fascist War.During World War II,China forged profound bonds with nations worldwide on the anti-fascist battlefield,enduring testaments to transnational solidarity.In the Lisbon Maru incident,Chinese fishermen from Zhoushan risked their lives to rescue 384 British prisoners of war,making 65 perilous trips under Japanese gunfire in a monumental display of courage and compassion.展开更多
On February 8, 2006, a piece of sad news came out of the Moon Bear Rescue Center in Chengdu, capital city of southwest China's Sichuan Province. Andrew, the first moon bear rescued by the Animals Asia Foundation, ...On February 8, 2006, a piece of sad news came out of the Moon Bear Rescue Center in Chengdu, capital city of southwest China's Sichuan Province. Andrew, the first moon bear rescued by the Animals Asia Foundation, which sponsors the center, died of liver cancer, thought to have arisen from the massive infec-展开更多
Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis,with high mortality and no proven therapy.Here,we reported a severe uremic calciphylaxis patient with progr...Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis,with high mortality and no proven therapy.Here,we reported a severe uremic calciphylaxis patient with progressive skin ischemia,large areas of painful malodorous ulcers,and mummified legs.Because of the worsening symptoms and signs refractory to conventional therapies,treatment with human amnion-derived mesenchymal stem cells(hAMSCs)was approved.Preclinical release inspections of hAMSCs,efficacy,and safety assessment,including cytokine secretory ability,immunocompetence,tumorigenicity,and genetics analysis in vitro,were introduced.We further performed acute and long-term hAMSC toxicity evaluations in C57BL/6 mice and rats,abnormal immune response tests in C57BL/6 mice,and tumorigenicity tests in neonatal Balbc-nu nude mice.After the preclinical research,the patient was treated with hAMSCs by intravenous and local intramuscular injection and external supernatant application to the ulcers.When followed up to 15 months,the blood-based markers of bone and mineral metabolism improved,with skin soft tissue regeneration and a more favorable profile of peripheral blood mononuclear cells.Skin biopsy after 1-month treatment showed vascular regeneration with mature noncalcified vessels within the dermis,and 20 months later,the re-epithelialization restored the integrity of the damaged site.No infusion or local treatment-related adverse events occurred.Thus,this novel long-term intravenous combined with local treatment with hAMSCs warrants further investigation as a potential regenerative treatment for uremic calciphylaxis due to effects of inhibiting vascular calcification,stimulating angiogenesis and myogenesis,anti-inflammatory and immune modulation,multidifferentiation,re-epithelialization,and restoration of integrity.展开更多
基金supported by the Key Project of National Natural Science Foundation of China(30530550)
文摘The objective of this study was to construct the infectious clone of encephalomyocarditis virus (EMCV) BJC3 strain.The genomic cDNA of the virus was amplified by three overlapping segments using RT-PCR,and cloned into low-copy plasmid pWSK29 to construct the full-length cDNA clone pWSKBJC3/ w.The pWSKBJC3/w was in vitro transcribed and transfected into BHK-21 cells to rescue the virus.The results showed that the full-length cDNA clone was infectious and the virus could be rescued in BHK-21 cells.The rescued virus designated RvBJC3W was identified by RT-PCR and indirect immunofluorescence assay(IFA).The rescued virus had similar growth characteristics to its parental virus BJC3 and retained pathogenicity for mice.Our results indicate that the first infectious cDNA clone of EMCV in China has been successfully established and provides an essential tool for investigating the molecular basis of pathogenicity of EMCV.
文摘1 On April 12,a group of campers in a California forest heard a crying noise.They discovered a small black bear cub that was all alone.The California Department of Fish and Wildlife kept an eye on the cub.When the mother didnt return,they took the bear to the Ramona Wildlife Center,which is run by the San Diego Humane Society.The center specializes in helping wild animals.
文摘ON May 20,2025,eighteen descendants of British prisoners of war(POWs)rescued in the Lisbon Maru incident arrived on Dongji Island in east China’s Zhejiang Province,after a long transoceanic journey.They joined descendants of the local fishermen who had saved their ancestors 83 years ago,gathering to witness the unveiling of a memorial erected in honor of the fishermen’s extraordinary bravery.At its center,the memorial bears the inscription:“Love knows no boundaries;Friendship transcends time.”
文摘1 On December 26,2024,a remarkable act of heroism took place at Poospatuck Creek.Kayla Masotto,a 28⁃year⁃old resident of Mastic,Long Island,stepped into the role of a life⁃saver when she witnessed a man fall through the ice on the lake.2 At about 6 pm,Kayla was washing vegetables in the kitchen when her attention was suddenly caught by a boy skating alone on the lake.In a split second,she witnessed the ice beneath him break,and the boy fell into the water.Without any hesitation,Kayla immediately grabbed her paddleboard(桨叶式冲浪板)and ran across her backyard,reaching the edge of the lake in seconds.
文摘Charlie,a father from Sunderland,was enjoying a meal with friends when sudden panic erupted at a nearby table.A woman began to choke,her face turning red as her breaths became shallow.Her friend wildly pounded her back,and others yelled for help.Without hesitation,Charlie sprang into action.
基金Supported by National Natural Science Foundation of China(Grant No.52475032)Central Government Guides Local Science and Technology Development Fund Projects(Grant No.246Z2001G)Hebei Provincial Natural Science Foundation Key Projects(Grant No.E2021203125).
文摘The existing research on rescue robots has focused mainly on reconnaissance,detection,and firefighting,and a small number of robots that can achieve human rescue have problems such as poor safety and stability and insufficient carrying capacity.This article addresses the above issues and cleverly combines the advantages of soft robotic arms,underactuated robotic arms,and suction cups based on the principles of bionics.A new design for a robotic arm was proposed,and its working principle was explained.Then,the human rescue process was divided into two stages,and the grasping force of the robotic arm in each stage was analyzed separately.Finally,a prototype of the principle was developed,and the feasibility of the design principle of the robotic arm was verified through grasping experiments on a cross-sectional contour model of the human chest.At the same time,grasping experiments were conducted on different objects to demonstrate the potential application of the robotic arm in grasping ground objects.This research proposes a stress envelope adsorption rescue robot arm inspired by the adhesion ability of the Drosera plant and the stress envelope effect,which can apply force to the entire surface of the human body,reduce local force on the human body,ensure load-bearing capacity and adaptability,and improve the safety and stability of rescue grasping.
文摘Researchers have discovered that mice instinctively exhibit rescue-like behavior towards anesthetized companions-a finding that suggests a biological basis for prosociality.The study,published in PNAS on April 23,2025,was led by Dr.HU Li from the Institute of Psychology of the Chinese Academy of Sciences(IPCAS)and Dr.CHEN Zhoufeng from Washington University School of Medicine and the Shenzhen Medical Academy of Research and Translation.
文摘A devastating disease called Huanglongbing(HLB) or citrus green is wiping out citrus trees across the globe. But we are seeing new hope. Scientists have recently uncovered a hidden battle happening inside citrus plants. Understanding this microscopic tug-of-war could be the key to rescuing our beloved oranges, lemons, and grapefruits.
文摘1 The grandfather was choking on a mouthful of food,unable to breathe and unable to cough.The grandson,recalling the important lesson learned during the 8-13 Project organized by the Italian Red Cross⁃Poggi⁃Sermide Committee,suggested performing the Heimlich manoeuvre(海姆立克急救法)on the elderly man.
文摘Objective:To explore the application effect of emergency rescue capability intervention among students in a university in Beijing.Methods:A total of 900 students from a university in Beijing in 2023 were selected as the research objects.Emergency rescue capability training was conducted from March 2023 to June 2023,once a month.The students’mastery of emergency rescue before and after the intervention was analyzed.Survey questionnaires were distributed to all college students to understand their channels and willingness to acquire emergency rescue knowledge.Results:A total of 886 valid questionnaires were collected in this study.The highest proportion of knowledge about China’s general emergency telephone number and how to dial the emergency rescue hotline was 100.00%.Among the strategies for dealing with cardiac arrest in CPR,the highest proportion was 336.34%.Among the four major first aid techniques of hemostasis,bandaging,fixation,transportation,the highest proportion of knowledge about the use of rubber band signs was 31.71%.Among the first aid techniques for heatstroke,poisoning,fire,and sharp instrument injuries,the principle of emergency treatment for severe gas poisoning had the highest proportion of 41.42%,showing significant differences.College students mainly acquire knowledge of emergency rescue capability through TV programs,health education lectures,and the internet.Around 61.40%of college students hope to learn more about prevention and control knowledge.Conclusion:After the intervention of emergency rescue capability,the emergency rescue capability of college students in this university has been significantly improved,showing a strong training effect,which is worthy of promotion.
基金Zhejiang Provincial Natural Science Foundation of China(No.LY22E050013)China Postdoctoral Science Foundation(No.2021M690545)National Natural Science Foundation of China(No.51805124).
文摘High-altitude rescue is dangerous and difficult.A new rescue method is proposed here based on electromagnetically launched tethered nets.Four electromagnetic launching units are attached to a revolving platform,from which four projectiles are launched.The four projectiles are connected to a tethered net,bringing it into motion.As the tethered net approaches and comes into contact with the object,the object will be trapped,and the rescue task will then be completed as long as the tethered net can be restored along with the trapped object.The structural design of the electromagnetic launching unit is presented with the established mathematical model.The motion characteristics of the launched projectiles are studied and their exit velocities are modeled and measured.Terminal velocities of these projectiles are characterized,and the final shape and position of the projected tethered net are obtained.This study validates the feasibility of using electromagnetically launched tethered nets to perform high-altitude rescues.
基金funded by the European Commission H2020 Research and Innovation Programme through the HARNESSTOM innovation action(Grant No.101000716)Grant CIPROM/2021/020(project SOLECO)funded by Conselleria d’Innovació,Universitats,Ciència i Societat Digital(Generalitat Valenciana,Spain)Pietro Gramazio received a post-doctoral fellowship(Grant No.RYC2021-031999-I)funded by MCIN/AEI/10.13039/501100011033 and by“European Union NextGenerationEU/PRTR”。
文摘Unlike other major crops,little research has been performed on tomato to reduce the generation time for speed breeding.We evaluated several agronomic treatments to reduce the generation time of tomato in the‘M82'(determinate)and‘Moneymaker'(indeterminate)varieties and evaluated the best combination in conjunction with embryo rescue.Five container sizes with volumes of 0.2 L(XS),0.45 L(S),0.8 L(M),1.3 L(L),and6 L(XL),were evaluated in the first experiment under the autumn cycle.We found that plants grown in XL containers exhibited better development and required less time from sowing to anthesis(DSA)and from anthesis to fruit ripening(DAR).In the second experiment,using XL containers in the autumn-winter cycle,we evaluated the effects of cold priming at the cotyledonary stage,water stress,P supplementation,and K supplementation on generation time.Compared to the control,we found that cold priming significantly reduced the number of leaves,plant height to first the inflorescence,and DSA(2.7 d),whereas K supplementation reduced the DAR(8.8 d).In contrast,water stress and P supplementation did not significantly affect any of the measured traits like DAR,DSA or fruit set.To validate these data,in a third experiment with XL containers in the spring-summer cycle,the combination of cold priming and K supplementation was tested,confirming the significant effect of this combination on the reduction of generation time(2.9 d for DSA and 3.9 d for DAR)compared to the control.Embryo rescue during the cell expansion cycle(average of 22.0 d and 23.3 d after anthesis for‘M82'and‘Moneymaker',respectively)allowed the shortening of the generation time by 8.7 d in‘M82'and 11.6 d in‘Moneymaker'compared to the in planta fruit ripening.The combination of agronomic treatments with embryo rescue can effectively increase the number of generations per year from three to four for speed breeding of tomato.
基金supported by Postgraduate Research&Practice Innovation Program of Jiangsu Province under Grant KYCX22_0290.
文摘The ability of cyborg locusts to achieve directional movement in complex outdoor environments is critical for search and rescue missions.Currently,there is a lack of research on motion control for cyborg locusts in outdoor settings.In this study,we developed cyborg locusts capable of performing directional locomotion in intricate outdoor environments,including jumping over obstacles,climbing slopes,traversing narrow pipelines,and accurately reaching predetermined targets along specified routes.We designed a miniature electrical backpack(10 mm×10 mm,0.75 g)capable of receiving stimulus parameters(frequency,duty ratio,and stimulation time)via Bluetooth commands from mobile phones.Electrical stimulation of locust sensory organs,such as the antennae and cercus,induced turning and jumping behaviors.Experi-mental testing of locust movement control was conducted under outdoor conditions with a short electrical stimulation interval.Results showed a positive correlation between locust turning angles and electrical stimulation parameters within a specified range,with an average jumping height exceeding 10 cm.Additionally,the success rate of locust turning and jumping behaviors correlated positively with the interval time between electrical stimulations.Adjusting these intervals during forward crawling phases increased the likelihood of the locusts jumping again.In conclusion,this study success-fully achieved directional locomotion control of cyborg locusts outdoors,providing insights and references for advancing search and rescue capabilities.
基金supported by the National Natural Science Foundation of China(No.52407064)。
文摘1.Opportunities for electric motor drives in the low-altitude economy The implementation plan for the innovative application of general aviation equipment(2024–2030)outlines that by 2027,new general aviation equipment will achieve commercial applications in urban air transport,logistics distribution and emergency rescue.
基金Baoding Science and Technology Plan Funded Project“The Value of Emergency Green Channel in the Treatment Rate of Acute Chest Pain Patients”(Project No.2441ZF291)。
文摘Objective: To analyze the clinical significance of the emergency green channel in the treatment of patients with acute chest pain. Methods: Sixty patients with acute chest pain treated between September 2022 and July 2024 were selected as the subjects of this study. They were divided into groups based on the order of treatment: the first 30 patients were included in the Green Channel group, where the emergency green channel was employed, while the remaining 30 patients were placed in the Regular Emergency group, receiving standard emergency treatment. The rescue time, hospitalization time, pain scores, incidence of adverse reactions, and quality of life between the Green Channel group and the Regular Emergency group were compared. Results: The rescue time and hospitalization time of the Green Channel group were shorter than those of the Regular Emergency group, with statistical significance (P < 0.05). The pain scores at 30, 60, 120, and 240 minutes after rescue in the Green Channel group were lower than those in the Regular Emergency group, with statistical significance (P < 0.05). The incidence of adverse reactions such as recurrent acute attacks, arrhythmia, heart failure, stroke, and shock in the Green Channel group was lower than that in the Regular Emergency group, with statistical significance (P < 0.05). The treatment satisfaction rate and success rate in the Green Channel group were 93.33% and 93.33%, respectively, while those in the Regular Emergency group were 73.33% and 73.33%. Both the satisfaction and success rates in the Green Channel group were higher than those in the Regular Emergency group, with statistical significance (P < 0.05). The quality of life in the Green Channel group was also higher than that in the Regular Emergency group, with statistical significance (P < 0.05). Conclusion: The emergency green channel plays a significant role in the treatment of patients with acute chest pain and is worthy of widespread clinical application.
文摘In recent years,with the increasing frequency of global Marine activities,the occurrence probability of Marine accidents and emergencies has also increased.As a new technical means,small unmanned aerial vehicles(UAVs)have shown great application potential in Marine search and rescue activities.In Marine search and rescue activities,small UAVs can quickly arrive at the scene of the accident and carry out efficient information collection and monitoring under its simple and flexible operation.Compared with traditional search and rescue methods,small UAVs can cover a wider area,provide more detailed and accurate on-site information,provide strong support for search and rescue decision-making,and thus improve the quality and efficiency of maritime rescue.In this regard,this paper first describes the application advantages of small UAVs in Marine search and rescue activities and then puts forward effective application paths,to provide some references for relevant researchers.
文摘The year 2025 marks the 80th anniversary of the victory in the Chinese People’s War of Resistance Against Japanese Aggression and the World Anti-Fascist War.During World War II,China forged profound bonds with nations worldwide on the anti-fascist battlefield,enduring testaments to transnational solidarity.In the Lisbon Maru incident,Chinese fishermen from Zhoushan risked their lives to rescue 384 British prisoners of war,making 65 perilous trips under Japanese gunfire in a monumental display of courage and compassion.
文摘On February 8, 2006, a piece of sad news came out of the Moon Bear Rescue Center in Chengdu, capital city of southwest China's Sichuan Province. Andrew, the first moon bear rescued by the Animals Asia Foundation, which sponsors the center, died of liver cancer, thought to have arisen from the massive infec-
基金funded by the National Natural Science Foundation of China(81270408,81570666,81730041,and 81671447)the International Society of Nephrology(ISN)Clinical Research Program(18-01-0247)+7 种基金Construction Program of Jiangsu Provincial Clinical Research Center Support System(BL2014084)Jiangsu Province Key Medical Personnel Project(ZDRCA2016002)CKD Anemia Research Foundation from China International Medical Foundation(Z-2017-24-2037)Outstanding Young and Middle-Aged Talents Support Program of The First Affiliated Hospital of Nanjing Medical University(Jiangsu Province Hospital)the National Key Research and Development Program of China(2017YFC1001303)the Program of Jiangsu Province Clinical Medical Center(YXZXB2016001,BL2012009)the State Key Laboratory of Reproductive Medicine Program(SKLRM-GC201803)the Program of Jiangsu Commission of Health(H201605).
文摘Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis,with high mortality and no proven therapy.Here,we reported a severe uremic calciphylaxis patient with progressive skin ischemia,large areas of painful malodorous ulcers,and mummified legs.Because of the worsening symptoms and signs refractory to conventional therapies,treatment with human amnion-derived mesenchymal stem cells(hAMSCs)was approved.Preclinical release inspections of hAMSCs,efficacy,and safety assessment,including cytokine secretory ability,immunocompetence,tumorigenicity,and genetics analysis in vitro,were introduced.We further performed acute and long-term hAMSC toxicity evaluations in C57BL/6 mice and rats,abnormal immune response tests in C57BL/6 mice,and tumorigenicity tests in neonatal Balbc-nu nude mice.After the preclinical research,the patient was treated with hAMSCs by intravenous and local intramuscular injection and external supernatant application to the ulcers.When followed up to 15 months,the blood-based markers of bone and mineral metabolism improved,with skin soft tissue regeneration and a more favorable profile of peripheral blood mononuclear cells.Skin biopsy after 1-month treatment showed vascular regeneration with mature noncalcified vessels within the dermis,and 20 months later,the re-epithelialization restored the integrity of the damaged site.No infusion or local treatment-related adverse events occurred.Thus,this novel long-term intravenous combined with local treatment with hAMSCs warrants further investigation as a potential regenerative treatment for uremic calciphylaxis due to effects of inhibiting vascular calcification,stimulating angiogenesis and myogenesis,anti-inflammatory and immune modulation,multidifferentiation,re-epithelialization,and restoration of integrity.
