Polydeoxyribonucleotide(PDRN)has been utilized in clinical practice for an extended period;however,its application in the cosmetics is relatively recent.This study aims to explore the research progress of PDRN regardi...Polydeoxyribonucleotide(PDRN)has been utilized in clinical practice for an extended period;however,its application in the cosmetics is relatively recent.This study aims to explore the research progress of PDRN regarding its skin repair and anti-aging properties.To evaluate the potential skin repair,soothing,anti-wrinkle and firming effects of PDRN essence via both in vitro and in vivo test method.This study employed in vitro and in vivo test to assess the skin repair and anti-wrinkle effects.The 3D skin model(FulKutis®)was utilized to verify the effects of the PDRN essence on anti-inflammation,barrier repair,and anti-aging.In human test,a randomized,half-face comparison test with PDRN essence and the placebo was conducted with 33 Chinese subjects who met the test criteria.During the test,the skin conditions in terms of the a*value,facial red area ratio,and Transepidermal Water Loss(TEWL)were evaluated at 30 min,4 h,1 day,and 3 days;the skin conditions in terms of skin elasticity and firmness,skin wrinkles were evaluated at 42 days.Subjects’self-assessments were collected at 3 days and 42 days.The FulKutis■experiments demonstrated that the PDRN essence significantly decreased the levels of IL-1α,TNF-α,and PGE2,and improved the protein levels of Filaggrin,Loricrin,Collagen I,Collagen IV,and the thickness of the epidermal living cell layer.In the human study,the a*value,red area ratio,TEWL,and skin-related parameters(R2,R5,R7,F4,and skin wrinkles)on the test face side exhibited greater improvement compared to the control face side with statistically significant differences.Additionally,subject selfassessments revealed high satisfaction with the PDRN essence.The PDRN essence applied after non-ablative fractional laser treatment promotes barrier repair and soothing effects,shortens the recovery period,and enhances facial firmness and wrinkle improvement at the crow’s feet and undereye regions.No adverse events related to the tested cosmetics were observed.展开更多
This study,based on the theory of shifting essence and changing Qi in Inner Canon of Huangdi,deeply explores the theoretical basis,operation method of Conception Vessel Dredging Therapy and its influence on human heal...This study,based on the theory of shifting essence and changing Qi in Inner Canon of Huangdi,deeply explores the theoretical basis,operation method of Conception Vessel Dredging Therapy and its influence on human health.Through case analysis and the statistical analysis of medical records during the pandemic,it reveals the remarkable effects of this method in regulating the endocrine system,improving metabolism,and relieving physical and mental diseases.It provides a theoretical and practical basis for the application of traditional Chinese medicine anti-aging therapy in the modern health field,and helps to explore new ways to delay aging and improve physical and mental health.展开更多
Traditional Mongolian medicine(TMM)integrates Tibetan and Chinese medicine with indigenous Mongolian practices,focusing on the balance of three core essences:Khii,Shar,and Badgan,derived from the Five Elements-earth,w...Traditional Mongolian medicine(TMM)integrates Tibetan and Chinese medicine with indigenous Mongolian practices,focusing on the balance of three core essences:Khii,Shar,and Badgan,derived from the Five Elements-earth,water,fire,wind,and space.These essences regulate both physical and psychological processes,and their imbalance,often caused by diet,behavior,or environment,leads to disease.TMM utilizes holistic diagnostic methods such as pulse diagnosis,visual inspection,and lifestyle evaluation to identify imbalances of three essences.Treatments include herbal remedies,dietary adjustments,behavior modification,and accessory therapies like moxibustion and massage to restore balance.This mini review examines the philosophical underpinnings,diagnostic techniques,and therapeutic strategies to Khii,Shar,and Badgan,highlighting their importance in both traditional and modern integrative healthcare.展开更多
托马斯.阿奎那的形而上学是以是(being)为中心、以本质(essence)和存在(existence)的关系学说为枢纽的存在论。阿奎那认为,形而上学或存在论所探讨的特殊的固有对象即是是(to on,esse,being)自身,或者称之为是之所以为是(esse in quantu...托马斯.阿奎那的形而上学是以是(being)为中心、以本质(essence)和存在(existence)的关系学说为枢纽的存在论。阿奎那认为,形而上学或存在论所探讨的特殊的固有对象即是是(to on,esse,being)自身,或者称之为是之所以为是(esse in quantum esse,being as beinginjeneral)。他在论证是自身时强调实在意义上的是重于逻辑意义的是。是(being)包括本质(essence)与存在(existence);本质(essence)与存在(existence)皆为是者(beings)。而存在(existence)先于本质(essence);存在(existence)是是(being)之最具体的、个别的、实体的、独一无二的完美实现(act)。托马斯.阿奎那的存在论哲学颠覆了传统哲学中存在与本质的位置,它以一种存在主义代替本质主义,从而在形而上学历史上掀起一场革命。展开更多
Human beings have no absolute,fixed essence. The essence of human beings is the combination of an innate substrate and acquired creation. As the degree of machine intelligence in the development of human society conti...Human beings have no absolute,fixed essence. The essence of human beings is the combination of an innate substrate and acquired creation. As the degree of machine intelligence in the development of human society continues to increase,human beings are constantly changing and creating their own essence,and they are also constantly liberated from the bondage of a certain single old essence,creating and enriching the richer and more diverse aspects of its essence. The transformation of labor from its alienation to its return is also a transformation of labor from the centralized form to the non-centralized form of human essence according to Karl Marx. The new fusion of artificial intelligence and bioengineering will lead to a new tracks of evolution that"reshapes and regenerates"life itself. This new evolutionary path will fuse the two-track evolution,biological evolution and cultural evolution,which have been relatively isolated in the traditional sense. If human beings are able to work hard together to design and implement a new social system that adapts to the future intelligent development,then what the comprehensive development of intelligence bring human beings about would be not a disaster,but a bright future.展开更多
This study aimed to establish a rapid analytical method to determine antioxidants in essence. A simple,efficient and practical, vortex-assisted, cloud-point extraction（VACPE） procedure is proposed for extracting and...This study aimed to establish a rapid analytical method to determine antioxidants in essence. A simple,efficient and practical, vortex-assisted, cloud-point extraction（VACPE） procedure is proposed for extracting and pre-concentrating four different of synthetic phenolic antioxidants（SPAs）, propyl gallate（PG）, tert-butylhydroquinone（TBHQ）, butylated hydroxyanisole（BHA）, butylated hydroxytoluene（BHT） in essence prior to high performance liquid chromatography（HPLC） analysis. The non-ionic surfactant, fatty alcohol polyoxyethylene ether-9（AEO-9）, was used as extractant and vortex-mixing was utilized to reduce extraction time and improve extraction efficiency. The effective parameters of the extraction process, such as volume of extraction solvent, pH, vortex-mixing time, equilibration temperature and time, were optimized. Under the optimum conditions, the linear range of PG, TBHQ,BHA and BHT was 8.0–800 ng/mL. All correlation coefficients of the calibration curves were higher than0.996 and relative standard deviations（RSD, n = 5） were 2.36%–5.46%. The proposed method was successfully applied to the extraction and determination of antioxidants in essence samples with satisfactory relative recoveries of 89.4%–103.5%. The results confirmed the SPAs of essence could be effectively monitored by this method and also established good reference criteria for essence.展开更多
The term Jingluo,translated as meridian or channel,is a core component of traditional Chinese medicine(TCM)and has played a fundamental role in guiding the clinical practice of acupuncture for thousands of years.Howev...The term Jingluo,translated as meridian or channel,is a core component of traditional Chinese medicine(TCM)and has played a fundamental role in guiding the clinical practice of acupuncture for thousands of years.However,the essence of the meridian remains elusive and is a source of both confusion and debate for researchers.In this study,a“4 D”systemic view on the essence of the meridian,namely substantial,functional,chronological,and cultural dimensions,was proposed based on a review of the ancient medical classics,recent research developments,and results from clinical practice.Previous studies have primarily focused on the substantial dimension of the meridian system,with scant interpretation about its functional domain.Neither systemic data nor evaluations have been adequately documented.Additionally,a limited but increasing number of studies have focused on the chronological and cultural dimensions.More investigations that embody the holistic concept of TCM and integrate the systemic modes and advanced techniques with dominant diseases of TCM need to be performed to obtain a more comprehensive understanding of the essence of meridians.The goal of this study is to yield useful information in understanding the essence of meridians and provide a reference and perspective for further research.展开更多
Although the "predictability barrier" is a scientific problem brought forward during the middle 1990’s,it has yet to be clearly understood.In this paper,the authors used model results to study the "pre...Although the "predictability barrier" is a scientific problem brought forward during the middle 1990’s,it has yet to be clearly understood.In this paper,the authors used model results to study the "predictability barrier" of some atmospheric (climatic) systems,including the equatorial Pacific sea surface temperature (SST),East Asia trough (EAT),and South Asia wind field (monsoon).It is shown that the "predictability barrier" appeared not only in predicting the SST in the equatorial Pacific,but also in predicting the atmospheric circulation systems,such as the EAT and the monsoon.The "predictability barrier" for predicting the different climate systems appeared not only in spring,but also in different seasons.It appeared in spring for the equatorial Pacific SST,in summer for the EAT,and in fall and winter for the monsoon.Further analyses showed that the fundamental physical essence of the "predictability barrier" is the seasonal variability characteristics of the atmospheric (climate) system.The "predictability barrier" would occur when the system was at its weakest or worst continuous phase.Furthermore,the models and error patterns also had an important impact on the "predictability barrier";good models and special error patterns can minimize the "predictability barrier".展开更多
OBJECTIVE: To investigate the effects of Zibushenjing Fang (formula for tonifying the kidney essence) on skeletal development and brain tissue antioxidation in mice with kidney essence insufficiency. METHODS: Fifty ma...OBJECTIVE: To investigate the effects of Zibushenjing Fang (formula for tonifying the kidney essence) on skeletal development and brain tissue antioxidation in mice with kidney essence insufficiency. METHODS: Fifty male Kunming mice were randomly divided into five groups: normal group, model group, Jinkuishenqi Wan group, Zibushenjing Fang high dose group, and Zibushenjing Fang low dose group, with 10 mice in each group. The model of kidney essence insufficiency syndrome was established in all the mice except the normal group by using a cat to threaten the mice and by swimming until exhaustion daily which lasted about 21 days. Mice in the model group were administered 20 mL/ kg -1 · d -1 of normal saline intragastrically. The Jinkuishenqi Wan group was given 2.7 g/kg-1 · d-1 ofa solution of Jinkuishenqi Wan. The Zibushenjing Fang high dose group was given 20 g/kg -1 · d -1 and the Zibushenjing Fang low dose group was given 10 g/kg -1 · d -1 of a solution of Zibushenjing Fang.The general condition of all the groups was observed, including the quantity of food and water intake, swimming time, length of femur, and weight of the femur and musculus quadriceps femoris. The total superoxide dismutase (T-SOD), glutathione peroxi- dase (GSH-Px), and methane dicarboxylic aldehyde (MDA) activities in the brain tissues were detected. RESULTS: Zibushenjing Fang could improve the manifestation of kidney essence insufficiency, increase the quantity of food and water intake, swimming time, femur length, and femur and musculus quadriceps femoris weight. It could also regulate the activities of T-SOD, GSH-Px, and MDA in brain tissue. CONCLUSION: Zibushenjing Fang may play an important role in treating kidney essence insufficiency syndrome by promoting body development and improving brain tissue antioxidation.展开更多
The concept of a circular economy can be applied to different business fields.The development of the existing industrial cycles with an overemphasis on economic development and the twisting concept of a circular econo...The concept of a circular economy can be applied to different business fields.The development of the existing industrial cycles with an overemphasis on economic development and the twisting concept of a circular economy,has limited any substantial contribution of the circular economy to environmental resources.In some cases,resources are even being consumed to create resource recycling.This puts a greater burden on the environment.To gain an understanding of the actual value of a circular economy to the environment and resources,an“Essence Analysis Model”has been used in this study.This combines sustainable development issues in a multi-faceted and multi-leveled analysis of the industrial circular economy model to guide its development more directly towards fundamentals.An analysis of the results of the“Essence Analysis Model”was used to find and change the original strategy,and develop a means of improving the circular economy model.The results of the study make an essential contribution to the sustainable development of environmental resources and the reduction of greenhouse gas emission.展开更多
Non-traditional security issues have arisen since the 1960s,especially after the end of the Cold War,and are becoming a major issue in world security and politics.This reflects tremendous changes in the world situatio...Non-traditional security issues have arisen since the 1960s,especially after the end of the Cold War,and are becoming a major issue in world security and politics.This reflects tremendous changes in the world situation.With diverse causes and plural referent objects,non-traditional security issues cover nearly all the problems in the world today and make development difficult to sustain.This raises the question of whether human society and the earth can survive.Power politics one-sidedly stresses the role of power,endangering the harmonious development of nations and the whole of human society.It is not at all conducive to the solution of non-traditional security issues.The solution of non-traditional security issues demands cooperation from all actors in the international community.Multiple means are needed to solve these issues.Equal dialogue between all the actors,which can easily be attained,will play an effective role,as long as all actors respect each other's differences.展开更多
OBJECTIVE:To investigate the safety of hair essence containing 0.05%purified bee venom(HE-PBV)on the skin and eyes of New Zealand White rabbits.METHODS:HE-PBV which contained 0.05%PBV,purified water,and glycerin,was u...OBJECTIVE:To investigate the safety of hair essence containing 0.05%purified bee venom(HE-PBV)on the skin and eyes of New Zealand White rabbits.METHODS:HE-PBV which contained 0.05%PBV,purified water,and glycerin,was used as the test substance.The skin-irritation test(SIT)and eye-irritation test(EIT)were conducted according to the Draize method.On the SIT,HE-PBV(0.5 m L)dropped gauze was attached both intact and abraded skin for 24 h.The other side of the skin was used as control.After 24 and 72 h,the treatment site was observed and scored according to evaluation criteria for skin reactions.On the EIT,the rabbits were divided into two groups:eye-washed(three rabbits)and non-eye-washed(six rabbits).HE-PBV(0.1 m L)was squirted into the right eye of rabbits.The left eye was untreated and used as a control.Then,20-30-s later,the eyes of rabbits in the eye-washed group were washed with^50 m L of physiologic(0.9%)salt solution.Then,1,2,3,4 and 7 d after the start of the EIT,the eyes and behavior of the rabbits were observed.The degree of eye irritation elicited by HE-PBV was determined in three steps and then the criteria of the classification of eye-irritation scores.RESULTS:The SIT revealed erythema and edema at the site of HE-PBV application.At 72 h,the body weight of rabbits was reduced slightly,but other symptoms(except erythema and edema)were not observed.The Primary Irritation Index score was0.6,and HE-PBV was deemed to be a slight irritant.The EIT did not show mortality or body-weight fluctuation,but hyperemic conjunctiva and eyelid closure were noted after HE-PBV administration.Except for these results,the score for the ophthalmic response on days 1,2,3,4 and 7 was 0,and HE-PBV was deemed to be a non-irritant.CONCLUSION:These data suggest that HE-PBV did not elicit eye irritation,but was a slight irritant to the skin of rabbits;the latter slight would have been due to the excipients used in manufacture of the hair essence because PBV has been shown to be safe.展开更多
12 patients with eosinophilic gastroenteritis were treated with prescriptions and drugs based mainly on the method of reinforcement of essence of the kidney. Remarkable curative effect was achieved in 9 cases and euth...12 patients with eosinophilic gastroenteritis were treated with prescriptions and drugs based mainly on the method of reinforcement of essence of the kidney. Remarkable curative effect was achieved in 9 cases and eutherapeutk effect in 3, Le, the cure rate was 100%. The efficacy began to appear hi a minimum of 7 days and a maximum of 12 days. There was no recurrence over 1 to 3 years’ follow-up observation.展开更多
Six representative interpretations about the core competence of the corporate proposed by the researchers both at home and abroad from different perspectives are introduced,which includes "Resource theory",&...Six representative interpretations about the core competence of the corporate proposed by the researchers both at home and abroad from different perspectives are introduced,which includes "Resource theory","Capacity theory","Integration theory of assets and mechanism","Theory of consumer surplus","Theory of institutions and systems" and "Theory of innovation". It is pointed out that although these interpretations play an active role in enriching the theory of core competence,it still faces the problems to further deepen these interpretations:the first problem is how to give a precise definition;the second is about its extension;the third is on the logical and practical relationship between the production mechanism and its sustainable competitive advantages;the fourth is the problems in the production process and the corresponding management. Both the systematic essence and features of core competence are introduced:the first is the system self-organization process produced within the corporate;the second is the interaction between corporate system and environment;it needs a growing and evolution process. This paper briefly describes the essence of core competence of agricultural high-tech corporate,introduces its five features including systematicness,integration,non-imitation,ductility and non-equilibrium,and finally explains its component parts,mainly including corporate culture system,technological innovation system,human resource system,management capability system,corporate production and marketing system,financial capability system and adaptability system.展开更多
Marxism holds that the internal essence of culture lies in the inherent identity of culture and man,and in the spiritual essence of man and that there would be no culture without man and man’s spirit.From the perspec...Marxism holds that the internal essence of culture lies in the inherent identity of culture and man,and in the spiritual essence of man and that there would be no culture without man and man’s spirit.From the perspective of the source of culture,it is man’s transcendence over nature.From the point of view of the process of its evolution,it is the sum of all human social relationships.Culture has the characteristics of man’s sociality and is shared by an entire cultural community.The essential complexity of culture is the logical expression of human thinking,and the logic reflection of cultural practice.Cultural practice,i.e.,human practice,is influenced and constrained not only by external practice,but also by the consciousness of man himself.Such two-way internal and external effects determine the particular law and logic of culture itself in its development,i.e.,the dialectical unity between decisiveness and selectivity,and between nationality and cosmopolitanness,in the development of culture;the dialectical unity between the consistency of basic trends in terms of the law of cultural development and the diversity of choices of paths;and the dialectical unity between diversity and unity concerning paths for the development of culture.展开更多
A hundred years ago, Planck and Einstein and others created quantum theories or quantum mechanics while they explained the photoelectric effect. Planck and Einstein empirically obtained a statistical relationship betw...A hundred years ago, Planck and Einstein and others created quantum theories or quantum mechanics while they explained the photoelectric effect. Planck and Einstein empirically obtained a statistical relationship between the energy of light quantum and the frequency of light but have not studied the physical process and essence of the photoelectric effect, so some photoelectric phenomena are difficult to be explained by existing quantum mechanics currently. In this paper, a dynamical process of orthogonal interaction between a photon and an electron to form a new state of matter in photoelectric effect experiments is studied so finding that the Planck constant is a product value of the mass, length, and velocity of a high-energy particle. The dynamics of the orthogonal collision of matter (particles) can not only give the physical process and essence of the photoelectric effect, but also have great significance for the further development of quantum mechanics. It can physically explain phenomena such as wave-particle duality and quantum entanglement in the motion of high-energy particles. Its prospects can be widely used in cosmic physics, macro physics, and micro physics.展开更多
<i><span style="font-family:Verdana;">Cordyceps</span></i><span style="font-family:Verdana;"> mycelium extract (Cs-4), Chicken Essence (CE), and their combination were...<i><span style="font-family:Verdana;">Cordyceps</span></i><span style="font-family:Verdana;"> mycelium extract (Cs-4), Chicken Essence (CE), and their combination were investigated for antioxidant and immunomodulatory activities in mouse models. Long-term treatment with Cs-4 or CE at equivalent human doses improved antioxidant status in various tissues, as evidenced by the enhancement of mitochondrial glutathione redox status in the brain, liver, heart, and kidney of mice. Cs-4 or CE treatment also produced an immunomodulatory action, as indicated by the potentiation of Concanavalin A-/lipopolysaccharide-induced proliferation of mouse splenocytes <i></i></span><i><i><span style="font-family:Verdana;">ex vivo</span></i><span style="font-family:Verdana;"></span></i>. While doubling of the equivalent human doses of Cs-4 and CE did not further enhance their antioxidant or immunopotentiating effects, the combined treatment with Cs-4 and CE at their respective equivalent human doses produced an additive effect, with the extents of stimulation being larger than those produced by Cs-4 or CE alone. The results have demonstrated for the first time that the combined use of Cs-4 and CE can produce an additive effect on both antioxidation and immunopotentiation that cannot otherwise be achieved by increasing the equivalent human doses of Cs-4 or CE alone.展开更多
文摘Polydeoxyribonucleotide(PDRN)has been utilized in clinical practice for an extended period;however,its application in the cosmetics is relatively recent.This study aims to explore the research progress of PDRN regarding its skin repair and anti-aging properties.To evaluate the potential skin repair,soothing,anti-wrinkle and firming effects of PDRN essence via both in vitro and in vivo test method.This study employed in vitro and in vivo test to assess the skin repair and anti-wrinkle effects.The 3D skin model(FulKutis®)was utilized to verify the effects of the PDRN essence on anti-inflammation,barrier repair,and anti-aging.In human test,a randomized,half-face comparison test with PDRN essence and the placebo was conducted with 33 Chinese subjects who met the test criteria.During the test,the skin conditions in terms of the a*value,facial red area ratio,and Transepidermal Water Loss(TEWL)were evaluated at 30 min,4 h,1 day,and 3 days;the skin conditions in terms of skin elasticity and firmness,skin wrinkles were evaluated at 42 days.Subjects’self-assessments were collected at 3 days and 42 days.The FulKutis■experiments demonstrated that the PDRN essence significantly decreased the levels of IL-1α,TNF-α,and PGE2,and improved the protein levels of Filaggrin,Loricrin,Collagen I,Collagen IV,and the thickness of the epidermal living cell layer.In the human study,the a*value,red area ratio,TEWL,and skin-related parameters(R2,R5,R7,F4,and skin wrinkles)on the test face side exhibited greater improvement compared to the control face side with statistically significant differences.Additionally,subject selfassessments revealed high satisfaction with the PDRN essence.The PDRN essence applied after non-ablative fractional laser treatment promotes barrier repair and soothing effects,shortens the recovery period,and enhances facial firmness and wrinkle improvement at the crow’s feet and undereye regions.No adverse events related to the tested cosmetics were observed.
基金Supported by Natural Science Foundation of China,Taoist Qi Healing the World Project(Project No.:71971359).
文摘This study,based on the theory of shifting essence and changing Qi in Inner Canon of Huangdi,deeply explores the theoretical basis,operation method of Conception Vessel Dredging Therapy and its influence on human health.Through case analysis and the statistical analysis of medical records during the pandemic,it reveals the remarkable effects of this method in regulating the endocrine system,improving metabolism,and relieving physical and mental diseases.It provides a theoretical and practical basis for the application of traditional Chinese medicine anti-aging therapy in the modern health field,and helps to explore new ways to delay aging and improve physical and mental health.
基金supported by Science and Technology Young Talents Development Project of Inner Mongolia Autonomous Region(NJYT22048)NMPA Key Laboratory Open Fund Project(MDK2023025).
文摘Traditional Mongolian medicine(TMM)integrates Tibetan and Chinese medicine with indigenous Mongolian practices,focusing on the balance of three core essences:Khii,Shar,and Badgan,derived from the Five Elements-earth,water,fire,wind,and space.These essences regulate both physical and psychological processes,and their imbalance,often caused by diet,behavior,or environment,leads to disease.TMM utilizes holistic diagnostic methods such as pulse diagnosis,visual inspection,and lifestyle evaluation to identify imbalances of three essences.Treatments include herbal remedies,dietary adjustments,behavior modification,and accessory therapies like moxibustion and massage to restore balance.This mini review examines the philosophical underpinnings,diagnostic techniques,and therapeutic strategies to Khii,Shar,and Badgan,highlighting their importance in both traditional and modern integrative healthcare.
文摘托马斯.阿奎那的形而上学是以是(being)为中心、以本质(essence)和存在(existence)的关系学说为枢纽的存在论。阿奎那认为,形而上学或存在论所探讨的特殊的固有对象即是是(to on,esse,being)自身,或者称之为是之所以为是(esse in quantum esse,being as beinginjeneral)。他在论证是自身时强调实在意义上的是重于逻辑意义的是。是(being)包括本质(essence)与存在(existence);本质(essence)与存在(existence)皆为是者(beings)。而存在(existence)先于本质(essence);存在(existence)是是(being)之最具体的、个别的、实体的、独一无二的完美实现(act)。托马斯.阿奎那的存在论哲学颠覆了传统哲学中存在与本质的位置,它以一种存在主义代替本质主义,从而在形而上学历史上掀起一场革命。
基金One of the research results of the National Social Science Fund Major Project “History,Current Situation and Future of Information Philosophy”(No.18ZDA027)
文摘Human beings have no absolute,fixed essence. The essence of human beings is the combination of an innate substrate and acquired creation. As the degree of machine intelligence in the development of human society continues to increase,human beings are constantly changing and creating their own essence,and they are also constantly liberated from the bondage of a certain single old essence,creating and enriching the richer and more diverse aspects of its essence. The transformation of labor from its alienation to its return is also a transformation of labor from the centralized form to the non-centralized form of human essence according to Karl Marx. The new fusion of artificial intelligence and bioengineering will lead to a new tracks of evolution that"reshapes and regenerates"life itself. This new evolutionary path will fuse the two-track evolution,biological evolution and cultural evolution,which have been relatively isolated in the traditional sense. If human beings are able to work hard together to design and implement a new social system that adapts to the future intelligent development,then what the comprehensive development of intelligence bring human beings about would be not a disaster,but a bright future.
基金supported by College of Life Science and Technology, Kunming University of Science and Technology
文摘This study aimed to establish a rapid analytical method to determine antioxidants in essence. A simple,efficient and practical, vortex-assisted, cloud-point extraction（VACPE） procedure is proposed for extracting and pre-concentrating four different of synthetic phenolic antioxidants（SPAs）, propyl gallate（PG）, tert-butylhydroquinone（TBHQ）, butylated hydroxyanisole（BHA）, butylated hydroxytoluene（BHT） in essence prior to high performance liquid chromatography（HPLC） analysis. The non-ionic surfactant, fatty alcohol polyoxyethylene ether-9（AEO-9）, was used as extractant and vortex-mixing was utilized to reduce extraction time and improve extraction efficiency. The effective parameters of the extraction process, such as volume of extraction solvent, pH, vortex-mixing time, equilibration temperature and time, were optimized. Under the optimum conditions, the linear range of PG, TBHQ,BHA and BHT was 8.0–800 ng/mL. All correlation coefficients of the calibration curves were higher than0.996 and relative standard deviations（RSD, n = 5） were 2.36%–5.46%. The proposed method was successfully applied to the extraction and determination of antioxidants in essence samples with satisfactory relative recoveries of 89.4%–103.5%. The results confirmed the SPAs of essence could be effectively monitored by this method and also established good reference criteria for essence.
基金supported by funding from Zhejiang Provincial Planned Project of Philosophy and Social Sciences(No.20NDJC118YB)the Key National Social Science Fund of China(No.18ZDA322)+2 种基金the National Social Science Fund of China(No.19XXW005)the International Cooperation and Exchange Project of Sichuan Provincial Science and Technology Department(No.2017HH0004)Social Science Fund for Universities of Sichuan Province(No.2021XT17)。
文摘The term Jingluo,translated as meridian or channel,is a core component of traditional Chinese medicine(TCM)and has played a fundamental role in guiding the clinical practice of acupuncture for thousands of years.However,the essence of the meridian remains elusive and is a source of both confusion and debate for researchers.In this study,a“4 D”systemic view on the essence of the meridian,namely substantial,functional,chronological,and cultural dimensions,was proposed based on a review of the ancient medical classics,recent research developments,and results from clinical practice.Previous studies have primarily focused on the substantial dimension of the meridian system,with scant interpretation about its functional domain.Neither systemic data nor evaluations have been adequately documented.Additionally,a limited but increasing number of studies have focused on the chronological and cultural dimensions.More investigations that embody the holistic concept of TCM and integrate the systemic modes and advanced techniques with dominant diseases of TCM need to be performed to obtain a more comprehensive understanding of the essence of meridians.The goal of this study is to yield useful information in understanding the essence of meridians and provide a reference and perspective for further research.
基金supported by the National Basic Research Program of China (Nos.2007CB411805 and 2006CB403603)the National Natural Science Foundation of China (No.U0833602)
文摘Although the "predictability barrier" is a scientific problem brought forward during the middle 1990’s,it has yet to be clearly understood.In this paper,the authors used model results to study the "predictability barrier" of some atmospheric (climatic) systems,including the equatorial Pacific sea surface temperature (SST),East Asia trough (EAT),and South Asia wind field (monsoon).It is shown that the "predictability barrier" appeared not only in predicting the SST in the equatorial Pacific,but also in predicting the atmospheric circulation systems,such as the EAT and the monsoon.The "predictability barrier" for predicting the different climate systems appeared not only in spring,but also in different seasons.It appeared in spring for the equatorial Pacific SST,in summer for the EAT,and in fall and winter for the monsoon.Further analyses showed that the fundamental physical essence of the "predictability barrier" is the seasonal variability characteristics of the atmospheric (climate) system.The "predictability barrier" would occur when the system was at its weakest or worst continuous phase.Furthermore,the models and error patterns also had an important impact on the "predictability barrier";good models and special error patterns can minimize the "predictability barrier".
文摘OBJECTIVE: To investigate the effects of Zibushenjing Fang (formula for tonifying the kidney essence) on skeletal development and brain tissue antioxidation in mice with kidney essence insufficiency. METHODS: Fifty male Kunming mice were randomly divided into five groups: normal group, model group, Jinkuishenqi Wan group, Zibushenjing Fang high dose group, and Zibushenjing Fang low dose group, with 10 mice in each group. The model of kidney essence insufficiency syndrome was established in all the mice except the normal group by using a cat to threaten the mice and by swimming until exhaustion daily which lasted about 21 days. Mice in the model group were administered 20 mL/ kg -1 · d -1 of normal saline intragastrically. The Jinkuishenqi Wan group was given 2.7 g/kg-1 · d-1 ofa solution of Jinkuishenqi Wan. The Zibushenjing Fang high dose group was given 20 g/kg -1 · d -1 and the Zibushenjing Fang low dose group was given 10 g/kg -1 · d -1 of a solution of Zibushenjing Fang.The general condition of all the groups was observed, including the quantity of food and water intake, swimming time, length of femur, and weight of the femur and musculus quadriceps femoris. The total superoxide dismutase (T-SOD), glutathione peroxi- dase (GSH-Px), and methane dicarboxylic aldehyde (MDA) activities in the brain tissues were detected. RESULTS: Zibushenjing Fang could improve the manifestation of kidney essence insufficiency, increase the quantity of food and water intake, swimming time, femur length, and femur and musculus quadriceps femoris weight. It could also regulate the activities of T-SOD, GSH-Px, and MDA in brain tissue. CONCLUSION: Zibushenjing Fang may play an important role in treating kidney essence insufficiency syndrome by promoting body development and improving brain tissue antioxidation.
文摘The concept of a circular economy can be applied to different business fields.The development of the existing industrial cycles with an overemphasis on economic development and the twisting concept of a circular economy,has limited any substantial contribution of the circular economy to environmental resources.In some cases,resources are even being consumed to create resource recycling.This puts a greater burden on the environment.To gain an understanding of the actual value of a circular economy to the environment and resources,an“Essence Analysis Model”has been used in this study.This combines sustainable development issues in a multi-faceted and multi-leveled analysis of the industrial circular economy model to guide its development more directly towards fundamentals.An analysis of the results of the“Essence Analysis Model”was used to find and change the original strategy,and develop a means of improving the circular economy model.The results of the study make an essential contribution to the sustainable development of environmental resources and the reduction of greenhouse gas emission.
文摘Non-traditional security issues have arisen since the 1960s,especially after the end of the Cold War,and are becoming a major issue in world security and politics.This reflects tremendous changes in the world situation.With diverse causes and plural referent objects,non-traditional security issues cover nearly all the problems in the world today and make development difficult to sustain.This raises the question of whether human society and the earth can survive.Power politics one-sidedly stresses the role of power,endangering the harmonious development of nations and the whole of human society.It is not at all conducive to the solution of non-traditional security issues.The solution of non-traditional security issues demands cooperation from all actors in the international community.Multiple means are needed to solve these issues.Equal dialogue between all the actors,which can easily be attained,will play an effective role,as long as all actors respect each other's differences.
基金Supported by Korea Institute of Planning and Evaluation for Technology in Food,Agriculture,Forestry and Fisheries through an Agri-Bio industry Technology Development Program funded by Ministry of Agriculture,Food and Rural Affairs(114070-3).
文摘OBJECTIVE:To investigate the safety of hair essence containing 0.05%purified bee venom(HE-PBV)on the skin and eyes of New Zealand White rabbits.METHODS:HE-PBV which contained 0.05%PBV,purified water,and glycerin,was used as the test substance.The skin-irritation test(SIT)and eye-irritation test(EIT)were conducted according to the Draize method.On the SIT,HE-PBV(0.5 m L)dropped gauze was attached both intact and abraded skin for 24 h.The other side of the skin was used as control.After 24 and 72 h,the treatment site was observed and scored according to evaluation criteria for skin reactions.On the EIT,the rabbits were divided into two groups:eye-washed(three rabbits)and non-eye-washed(six rabbits).HE-PBV(0.1 m L)was squirted into the right eye of rabbits.The left eye was untreated and used as a control.Then,20-30-s later,the eyes of rabbits in the eye-washed group were washed with^50 m L of physiologic(0.9%)salt solution.Then,1,2,3,4 and 7 d after the start of the EIT,the eyes and behavior of the rabbits were observed.The degree of eye irritation elicited by HE-PBV was determined in three steps and then the criteria of the classification of eye-irritation scores.RESULTS:The SIT revealed erythema and edema at the site of HE-PBV application.At 72 h,the body weight of rabbits was reduced slightly,but other symptoms(except erythema and edema)were not observed.The Primary Irritation Index score was0.6,and HE-PBV was deemed to be a slight irritant.The EIT did not show mortality or body-weight fluctuation,but hyperemic conjunctiva and eyelid closure were noted after HE-PBV administration.Except for these results,the score for the ophthalmic response on days 1,2,3,4 and 7 was 0,and HE-PBV was deemed to be a non-irritant.CONCLUSION:These data suggest that HE-PBV did not elicit eye irritation,but was a slight irritant to the skin of rabbits;the latter slight would have been due to the excipients used in manufacture of the hair essence because PBV has been shown to be safe.
文摘12 patients with eosinophilic gastroenteritis were treated with prescriptions and drugs based mainly on the method of reinforcement of essence of the kidney. Remarkable curative effect was achieved in 9 cases and eutherapeutk effect in 3, Le, the cure rate was 100%. The efficacy began to appear hi a minimum of 7 days and a maximum of 12 days. There was no recurrence over 1 to 3 years’ follow-up observation.
文摘Six representative interpretations about the core competence of the corporate proposed by the researchers both at home and abroad from different perspectives are introduced,which includes "Resource theory","Capacity theory","Integration theory of assets and mechanism","Theory of consumer surplus","Theory of institutions and systems" and "Theory of innovation". It is pointed out that although these interpretations play an active role in enriching the theory of core competence,it still faces the problems to further deepen these interpretations:the first problem is how to give a precise definition;the second is about its extension;the third is on the logical and practical relationship between the production mechanism and its sustainable competitive advantages;the fourth is the problems in the production process and the corresponding management. Both the systematic essence and features of core competence are introduced:the first is the system self-organization process produced within the corporate;the second is the interaction between corporate system and environment;it needs a growing and evolution process. This paper briefly describes the essence of core competence of agricultural high-tech corporate,introduces its five features including systematicness,integration,non-imitation,ductility and non-equilibrium,and finally explains its component parts,mainly including corporate culture system,technological innovation system,human resource system,management capability system,corporate production and marketing system,financial capability system and adaptability system.
基金a phased achievement of the “Study on the Practice Path of Core Socialist Values in the Rural Areas from the Perspective of Cultural Tradition”(15BKS116),a project supported by the National Social Science Fund of China
文摘Marxism holds that the internal essence of culture lies in the inherent identity of culture and man,and in the spiritual essence of man and that there would be no culture without man and man’s spirit.From the perspective of the source of culture,it is man’s transcendence over nature.From the point of view of the process of its evolution,it is the sum of all human social relationships.Culture has the characteristics of man’s sociality and is shared by an entire cultural community.The essential complexity of culture is the logical expression of human thinking,and the logic reflection of cultural practice.Cultural practice,i.e.,human practice,is influenced and constrained not only by external practice,but also by the consciousness of man himself.Such two-way internal and external effects determine the particular law and logic of culture itself in its development,i.e.,the dialectical unity between decisiveness and selectivity,and between nationality and cosmopolitanness,in the development of culture;the dialectical unity between the consistency of basic trends in terms of the law of cultural development and the diversity of choices of paths;and the dialectical unity between diversity and unity concerning paths for the development of culture.
文摘A hundred years ago, Planck and Einstein and others created quantum theories or quantum mechanics while they explained the photoelectric effect. Planck and Einstein empirically obtained a statistical relationship between the energy of light quantum and the frequency of light but have not studied the physical process and essence of the photoelectric effect, so some photoelectric phenomena are difficult to be explained by existing quantum mechanics currently. In this paper, a dynamical process of orthogonal interaction between a photon and an electron to form a new state of matter in photoelectric effect experiments is studied so finding that the Planck constant is a product value of the mass, length, and velocity of a high-energy particle. The dynamics of the orthogonal collision of matter (particles) can not only give the physical process and essence of the photoelectric effect, but also have great significance for the further development of quantum mechanics. It can physically explain phenomena such as wave-particle duality and quantum entanglement in the motion of high-energy particles. Its prospects can be widely used in cosmic physics, macro physics, and micro physics.
文摘<i><span style="font-family:Verdana;">Cordyceps</span></i><span style="font-family:Verdana;"> mycelium extract (Cs-4), Chicken Essence (CE), and their combination were investigated for antioxidant and immunomodulatory activities in mouse models. Long-term treatment with Cs-4 or CE at equivalent human doses improved antioxidant status in various tissues, as evidenced by the enhancement of mitochondrial glutathione redox status in the brain, liver, heart, and kidney of mice. Cs-4 or CE treatment also produced an immunomodulatory action, as indicated by the potentiation of Concanavalin A-/lipopolysaccharide-induced proliferation of mouse splenocytes <i></i></span><i><i><span style="font-family:Verdana;">ex vivo</span></i><span style="font-family:Verdana;"></span></i>. While doubling of the equivalent human doses of Cs-4 and CE did not further enhance their antioxidant or immunopotentiating effects, the combined treatment with Cs-4 and CE at their respective equivalent human doses produced an additive effect, with the extents of stimulation being larger than those produced by Cs-4 or CE alone. The results have demonstrated for the first time that the combined use of Cs-4 and CE can produce an additive effect on both antioxidation and immunopotentiation that cannot otherwise be achieved by increasing the equivalent human doses of Cs-4 or CE alone.
