The anti-wrinkle,relieving effect and safety of a group of hexapeptide compounds(HCs)were evaluated by in vitro antioxidant test,hyaluronidase inhibition test and human clinical test.The results showed that HCs posses...The anti-wrinkle,relieving effect and safety of a group of hexapeptide compounds(HCs)were evaluated by in vitro antioxidant test,hyaluronidase inhibition test and human clinical test.The results showed that HCs possess+high overall antioxidant activity,and the scavenging activity of ABTS•radical and DPPH radical by 4 mg/mL HCs solution were(92.23±1.15)%and(90.24±1.25)%.The scavenging activity of PTIO radical by 80 mg/mL HCs solution was(80.29±2.41)%.The inhibition rate of 80 mg/mL HCs on hyaluronidase was(75.00±6.13)%.The test of clinical results showed that the HCs have good anti-wrinkle and relieving effect,and no case of grade 1 or above skin adverse reactions occurred,indicating that HCs have good safety.展开更多
目的:探讨通窍止痛汤联合动脉瘤栓塞术治疗高龄动脉瘤性蛛网膜下腔出血患者的临床疗效。方法:纳入60例高龄动脉瘤性蛛网膜下腔出血病例,按照随机数字表法分配成两组,对照组给予动脉瘤栓塞术治疗,联合组给予动脉瘤栓塞术联合通窍止痛汤...目的:探讨通窍止痛汤联合动脉瘤栓塞术治疗高龄动脉瘤性蛛网膜下腔出血患者的临床疗效。方法:纳入60例高龄动脉瘤性蛛网膜下腔出血病例,按照随机数字表法分配成两组,对照组给予动脉瘤栓塞术治疗,联合组给予动脉瘤栓塞术联合通窍止痛汤治疗。观察两组治疗后临床疗效、不良反应及治疗前后格拉斯哥昏迷量表(Glasgow Coma Scale,GCS)评分、症状积分的变化情况。结果:联合组总有效率[83.33%(25/30)]高于对照组76.67%(23/30)(P<0.05);在治疗后第3、7、14天,联合组GCS评分及症状积分的变化幅度大于对照组(P<0.05);两组在治疗期间均未发生明显不良反应。结论:通窍止痛汤联合动脉瘤栓塞术治疗高龄动脉瘤性蛛网膜下腔出血,可明显减轻患者临床症状,提高患者术后生活质量。展开更多
文摘The anti-wrinkle,relieving effect and safety of a group of hexapeptide compounds(HCs)were evaluated by in vitro antioxidant test,hyaluronidase inhibition test and human clinical test.The results showed that HCs possess+high overall antioxidant activity,and the scavenging activity of ABTS•radical and DPPH radical by 4 mg/mL HCs solution were(92.23±1.15)%and(90.24±1.25)%.The scavenging activity of PTIO radical by 80 mg/mL HCs solution was(80.29±2.41)%.The inhibition rate of 80 mg/mL HCs on hyaluronidase was(75.00±6.13)%.The test of clinical results showed that the HCs have good anti-wrinkle and relieving effect,and no case of grade 1 or above skin adverse reactions occurred,indicating that HCs have good safety.
文摘目的:探讨通窍止痛汤联合动脉瘤栓塞术治疗高龄动脉瘤性蛛网膜下腔出血患者的临床疗效。方法:纳入60例高龄动脉瘤性蛛网膜下腔出血病例,按照随机数字表法分配成两组,对照组给予动脉瘤栓塞术治疗,联合组给予动脉瘤栓塞术联合通窍止痛汤治疗。观察两组治疗后临床疗效、不良反应及治疗前后格拉斯哥昏迷量表(Glasgow Coma Scale,GCS)评分、症状积分的变化情况。结果:联合组总有效率[83.33%(25/30)]高于对照组76.67%(23/30)(P<0.05);在治疗后第3、7、14天,联合组GCS评分及症状积分的变化幅度大于对照组(P<0.05);两组在治疗期间均未发生明显不良反应。结论:通窍止痛汤联合动脉瘤栓塞术治疗高龄动脉瘤性蛛网膜下腔出血,可明显减轻患者临床症状,提高患者术后生活质量。
