The key parameters that characterize the morphological quality of multi-layer and multi-pass metal laser deposited parts are the surface roughness and the error between the actual printing height and the theoretical m...The key parameters that characterize the morphological quality of multi-layer and multi-pass metal laser deposited parts are the surface roughness and the error between the actual printing height and the theoretical model height.The Taguchi method was employed to establish the correlations between process parameter combinations and multi-objective characterization of metal deposition morphology(height error and roughness).Results show that using the signal-to-noise ratio and grey relational analysis,the optimal parameter combination for multi-layer and multi-pass deposition is determined as follows:laser power of 800 W,powder feeding rate of 0.3 r/min,step distance of 1.6 mm,and scanning speed of 20 mm/s.Subsequently,a Genetic Bayesian-back propagation(GB-BP)network is constructed to predict multi-objective responses.Compared with the traditional back propagation network,the GB-back propagation network improves the prediction accuracy of height error and surface roughness by 43.14%and 71.43%,respectively.This network can accurately predict the multi-objective characterization of morphological quality of multi-layer and multi-pass metal deposited parts.展开更多
The year 2026 marks the 70th anniversary of the establishment of diplomatic relations between China and African countries.It also marks the launch of the China-Africa Year of People-to-People Exchanges.At this pivotal...The year 2026 marks the 70th anniversary of the establishment of diplomatic relations between China and African countries.It also marks the launch of the China-Africa Year of People-to-People Exchanges.At this pivotal juncture linking past achievements with future development,Wang Yi,member of the Political Bureau of the Communist Party of China Central Committee and foreign minister,continued the longstanding diplomatic tradition under which the Chinese foreign minister makes Africa the destination of the first overseas visit of the year,a practice upheld for 36 consecutive years,underscoring the stability,continuity and sincerity of China’s policy towards Africa.展开更多
Understory bryophytes play unique and disproportionately important roles in water retention,biogeochemical cycling,and biodiversity conservation,and serve as bioindicators of environmental health in forest ecosystems....Understory bryophytes play unique and disproportionately important roles in water retention,biogeochemical cycling,and biodiversity conservation,and serve as bioindicators of environmental health in forest ecosystems.However,biogeographical research on the biomass of forest bryophytes is inadequately studied and has been limited to elevational gradients.We conducted a systematic cross-regional survey of bryophyte biomass across 413 forest sites in Sichuan Province,China.We analyzed how each environmental variable,including climatic and atmospheric factors,overstory covers,and soil nutrients,relates to bryophyte biomass and quantified their relative contributions.The results indicate that,largely similar to previous local investigations and experiments,at a large scale,bryophytes are abundant in forests with lower temperature,nitrogen deposition,vapor pressure deficit,and tree and herb covers,as well as higher light availability.Moreover,bryophyte biomass is positively associated with soil carbon and nitrogen content.These environmental variables are closely related and jointly influence bryophyte biomass,with mean annual temperature being the most significant factor(accounting for 83%of the relative contribution).The biogeographical patterns of bryophyte biomass contribute to deepening our understanding of their adaptations to multiple environmental variables and enable us to predict their responses to global climate change.These patterns also provide essential evidence for establishing more accurate terrestrial vegetation ecosystem models.展开更多
On the threshold of 55 years of diplomatic relations,Cyprus and China stand to gain significantly by deepening their cooperation in trade,tourism,and green technology,guided by mutual respect and shared principles.WIT...On the threshold of 55 years of diplomatic relations,Cyprus and China stand to gain significantly by deepening their cooperation in trade,tourism,and green technology,guided by mutual respect and shared principles.WITH a population of approximately one million,Cyprus is a small country compared to China,which is home to more than 1.4 billion people.展开更多
The quantitative relationship between modern pollen and vegetation provides a critical foundation for reconstructing past vegetation,with relative pollen productivity(RPP)serving as a key calibration parameter.However...The quantitative relationship between modern pollen and vegetation provides a critical foundation for reconstructing past vegetation,with relative pollen productivity(RPP)serving as a key calibration parameter.However,in subtropical evergreen broadleaved forests(SEBFs)in China,RPP studies remain scarce,and the impact of human disturbances on RPP estimates has yet to be adequately assessed,limiting the accuracy of quantitative palaeovegetation reconstructions.This study was conducted in Dinghu Mountain Nature Reserve and its surrounding areas in Zhaoqing,Guangdong Province,and included 31 sampling sites.We performed pollen analysis alongside detailed vegetation surveys and utilized ERV submodel 2 and Prentice’s model to estimate the RPP of 9 common plant taxa in the southern SEBFs.There was a particular focus on evaluating the interference effects of bamboo plantations on the estimation of RPP.The results indicate that bamboo within the family Poaceae contributes minimally to surface soil Poaceae pollen because of its unique flowering characteristics,such as long flowering cycles and monocarpic reproduction.The incorporation of bamboo into the Poaceae vegetation coverage in the analysis led to excessively high RPP values for the other taxa.When bamboo coverage was removed from the Poaceae family,the recalculated RPP values aligned closely with those reported in previous studies.The RPP values,ranked from highest to lowest,were as follows:Castanopsis(12.33±0.03)>Araliaceae(1.60±0.03)>Mallotus(1.53±0.26)>Pinus(1.47±0.03)>Rosaceae(1.07±0.02)>Poaceae(1±0)>Euphorbiaceae(0.44±0.03)>Anacardiaceae(0.26±0.03)>Theaceae(0.15±0).Notably,the RPP values for Mallotus,Araliaceae,Theaceae,and Euphorbiaceae represent the first estimates for China’s subtropical region.Differences between certain RPP estimates and those of previous studies may be attributed to factors such as species composition,vegetation structure,and model selection.The findings of this study highlight that due to the widespread distribution of artificial bamboo forests in China’s subtropical regions,future RPP studies should carefully consider the influence of Poaceae.This consideration is essential for improving the accuracy of the application of fossil pollen for quantitative paleo-vegetation reconstruction in these regions.展开更多
The composition−property relationship of 18 quaternary high entropy diborides(HEBs)consisting of boron and IVB,VB and VIB transition metals(TM)was investigated using first-principles calculations.A valence electron co...The composition−property relationship of 18 quaternary high entropy diborides(HEBs)consisting of boron and IVB,VB and VIB transition metals(TM)was investigated using first-principles calculations.A valence electron concentration−relative electronegativity(VEC−REN)composite descriptor was developed to effectively predict the mechanical properties of HEBs.The results demonstrate that with a fixed VEC,the rise of the REN makes HEBs harder but more brittle when the electronegativity of doped TM atoms is lower than that of boron atoms.However,HEBs become softer and more ductile as REN increases if the doped TM atoms have higher electronegativity than boron atoms.The VEC−REN composite descriptor can accurately classify and predict the mechanical properties of HEBs with different components,which provides important theoretical guidance for the rapid design and development of novel high-entropy ceramic materials.展开更多
The stress-strain behavior of calcareous sand is significantly influencedby particle breakage(B)and initial relative density(Dri),but few constitutive models consider their combined effects.To bridge this gap,we condu...The stress-strain behavior of calcareous sand is significantly influencedby particle breakage(B)and initial relative density(Dri),but few constitutive models consider their combined effects.To bridge this gap,we conducted a series of triaxial tests on calcareous sand with varying Dri and stress paths,examining particle breakage and critical state behavior.Key findingsinclude:(1)At a constant stress ratio(η),B follows a hyperbolic relationship with mean effective stress(p'),and for a given p',B increases proportionally withη;(2)The critical state line(CSL)moves downward with increasing Dri,whereas the critical state friction angle(φcs)decreases with increasing B.Based on these findings,we propose a unifiedbreakage evolution model to quantify particle breakage in calcareous sand under various loading conditions.Integrating this model with the Normal Consolidation Line(NCL)and CSL equations,we successfully simulate the steepening of NCL and CSL slopes as B increases with the onset of particle breakage.Furthermore,we quantitatively evaluate the effect of B onφcs.Finally,within the framework of Critical State Soil Mechanics and Hypoplasticity theory,we develop a hypoplastic model incorporating B and Dri.The model is validated through strong agreement with experimental results across various initial relative densities,stress paths and drainage conditions.展开更多
Bread wheat(Triticum aestivum L.)is a staple hexaploid crop with numerous wild relatives.However,domestication and modern breeding have significantly narrowed its genetic diversity,diminishing its capacity to adapt to...Bread wheat(Triticum aestivum L.)is a staple hexaploid crop with numerous wild relatives.However,domestication and modern breeding have significantly narrowed its genetic diversity,diminishing its capacity to adapt to climate change.Wild relatives of wheat serve as a vital reservoir of genetic diversity,offering traits thatenhance its resistance to various biotic and abiotic stresses.Over recent decades,remarkable progress has been made in utilizing superior genes from wild relatives to bolster wheat's defenses against diseases and pests,though the exploration of genes conferring abiotic stress tolerance has lagged behind.In this review,we summarize key advancements in the utilization of wild relatives for wheat enhancement over the past century,emphasizing both theoretical and technological innovations.Furthermore,we evaluate the potential contributions of wild relatives to address production challenges posed by climate change.We also explore strategies for isolating superior genes and developing prebreeding germplasm to support the future development of climate-resilient wheat varieties.展开更多
Loday introduced di-associative algebras and tri-associative algebras motivated by periodicity phenomena in algebraic K-theory.The purpose of this paper is to study the splittings of operations on di-associative algeb...Loday introduced di-associative algebras and tri-associative algebras motivated by periodicity phenomena in algebraic K-theory.The purpose of this paper is to study the splittings of operations on di-associative algebras and tri-associative algebras.We introduce the notion of a quad-dendriform algebra,which is a splitting of a di-associative algebra.We show that a relative averaging operator on dendriform algebras gives rise to a quad-dendriform algebra.Furthermore,we introduce the notion of six-dendriform algebras,which are splittings of the tri-associative algebras,and demonstrate that homomorphic relative averaging operators induce six-dendriform algebras.展开更多
The Almus Fault Zone(AFZ)is one of the major splay faults of the North Anatolian Fault Zone(NAFZ)and is important for understanding its tectonic features and assessing regional seismic hazards.This research presents t...The Almus Fault Zone(AFZ)is one of the major splay faults of the North Anatolian Fault Zone(NAFZ)and is important for understanding its tectonic features and assessing regional seismic hazards.This research presents the integration of morphometric indices to quantitatively assess the spatial variation of tectonic activity along the AFZ.The AFZ is an active fault with both strike-slip and normal fault components and consists of two main branches,Mercimekdağı-Çamdere Fault(MÇF)and Tokat Fault(TF)segments.This study aims to assess the relative tectonic activity of the AFZ using various morphometric indices,based on a 10 m resolution DEM,with the aid of ArcGIS and MATLAB software.For this purpose,morphometric indices such as hypsometric integral(HI:0.35-0.65),mountain front sinuosity(Smf:1.3-1.44),valley floor width-height ratio(Vf:0.15-2.28),asymmetry factor(AF:23-77),drainage basin shape(Bs:1.13-6.10)and normalized steepness index(ksn:1-498)were applied to 53 drainage basins.When the Smf and mean Vf indices results were evaluated,it was calculated that the uplift ratio of the region was more than 0.5 mm/yr.The spatial distribution of the relative tectonic activity(Iat)of the area was revealed by combining the obtained morphometric indices analysis results.According to the Iat result,it was concluded that the MercimekdağıÇamdere Fault and Tokat Fault segments have high tectonic activity,but the Mercimekdağı-Çamdere Fault segment has higher tectonic activity.The results obtained were also confirmed by field observations.This research provides valuable information for the evaluation of tectonic activity in drainage systems controlled by splay faults.展开更多
According to the 2024 global cancer data from GLOBOCAN,liver cancer ranks the 6th most common malignancy and the 3rd leading cause of cancer-related mortality worldwide[1].Among these cases,hepatocellular carcinoma(HC...According to the 2024 global cancer data from GLOBOCAN,liver cancer ranks the 6th most common malignancy and the 3rd leading cause of cancer-related mortality worldwide[1].Among these cases,hepatocellular carcinoma(HCC)accounts for approximately 85%−90%[2,3].Its incidence and mortality rates remain persistently high worldwide.However,China has the highest incidence and mortality rates of the disease in the world[4].And the majority of patients are diagnosed at intermediate or advanced stages.Thus,identifying novel tumor biomarkers for early detection and implementing precision therapy has long been a key focus of research.展开更多
Educational cooperation,as the cornerstone and vanguard of people-to-people exchanges and practical cooperation between China and Africa,holds irreplaceable strategic significance for enhancing the quality of Africa&#...Educational cooperation,as the cornerstone and vanguard of people-to-people exchanges and practical cooperation between China and Africa,holds irreplaceable strategic significance for enhancing the quality of Africa's human capital and accelerating its structural transformation and modernization process.This paper employs“demand–supply–adaptation”as its core analytical framework and aims to systematically explore how the educational cooperation between China and Africa can serve Africa's goal of modernization more precisely and effectively.First,through reviewing and analyzing the domestic and international research literature,this paper clarifies the focus,paradigms,and shortcomings of existing research,identifying the knowledge contribution of this study.Second,utilizing detailed macro-level data,case studies,and comparative research methods,it comprehensively presents the multidimensional status,structural characteristics,and development trends of China–Africa educational cooperation in areas such as student exchanges,cooperative education,vocational and technical training,language and cultural exchange,and emerging digital education.This paper also deeply analyzes the pressing and specific demands placed on the education system by Africa's modernization development across key dimensions like economic diversification,industrialization,agricultural modernization,social governance upgrading,and digital transformation.Third,based on the cooperative principle of“Africa's needs and China's strengths,”this paper innovatively proposes systematic countermeasures and suggestions for constructing new,multi-level,high-quality,sustainable,and future-oriented pathways for China–Africa educational cooperation:(a)promoting the strategic focus of cooperation to extend from“hard infrastructure”support to empowering“soft infrastructure”;(b)deepening the integration of industry and education and school–enterprise collaboration to precisely align with Africa's industrial development needs;vigorously developing digital education and jointly building a smart education ecosystem to help Africa bridge the digital divide;(c)improving an evidence-based,third-party evaluation system for cooperative effectiveness and a full-process quality assurance system;and(d)promoting the collaborative participation of multiple actors including governments,schools,enterprises,think tanks,and social organizations to build a new cooperative pattern of coconstruction,co-governance,and shared benefits.展开更多
Aging,mitochondria,and neurodegenerative diseases:Aging is often viewed as the buildup of changes that lead to the gradual transformations associated with getting older,along with a rising likelihood of disease and mo...Aging,mitochondria,and neurodegenerative diseases:Aging is often viewed as the buildup of changes that lead to the gradual transformations associated with getting older,along with a rising likelihood of disease and mortality.Although organis m-wide deterioration is observed during aging,organs with high metabolic demand,such as the brain,are more vulnerable.展开更多
1.Introduction In recent years,intensifying climate extremes have triggered a sharp increase in global natural disasters,over 90%attributable to water-related hazards,particularly floods(Hirabayashi et al.,2013).Over ...1.Introduction In recent years,intensifying climate extremes have triggered a sharp increase in global natural disasters,over 90%attributable to water-related hazards,particularly floods(Hirabayashi et al.,2013).Over the past two decades,floods have inundated approximately 2.23 million km2 of land worldwide(Tellman et al.,2021),affecting over 250 million people and causing economic losses exceeding USD 651 billion(Devitt et al.,2023).Recent catastrophic floods in Pakistan,landslides in Indonesia,and dike breaches in China have intensified concerns over the effectiveness of current flood management strategies.展开更多
British Prime Minister Keir Starmer’s visit to China underscores economic cooperation and strategic stability amid global uncertainties.U.K.Prime Minister Keir Starmer’s visit to China in January marks a significant...British Prime Minister Keir Starmer’s visit to China underscores economic cooperation and strategic stability amid global uncertainties.U.K.Prime Minister Keir Starmer’s visit to China in January marks a significant shift of Britain toward a more pragmatic and stability-oriented approach in Sino-British relations.After years of political tensions and limited high-level engagement,this trip underscores London’s intent to rebuild ties based on mutual economic and strategic interests.展开更多
This study investigated biomass allocation in young stands of European beech(Fagus sylvatica L.)and Norway spruce(Picea abies(L.)Karst.)across 31 forest sites in the Western Carpathians,Slovakia.A total of 541 trees a...This study investigated biomass allocation in young stands of European beech(Fagus sylvatica L.)and Norway spruce(Picea abies(L.)Karst.)across 31 forest sites in the Western Carpathians,Slovakia.A total of 541 trees aged 2–10 years,originating from natural regeneration and planting,were destructively sampled to quantify biomass in four components:foliage,branches,stems,and roots.Generalized non-linear least squares(GNLS)models with a weighing variance function outperformed log-transformed seemingly unrelated regression(SUR)models in terms of accuracy and robustness,especially for foliage and branch biomass.When using height as the predictor,SUR models tended to underestimate biomass in planted beech,leading to notable underprediction of aboveground and total biomass.Biomass allocation patterns varied significantly by species and regeneration origin.Using a non-linear system of equations and component ratio modelling,we found out that planted spruce displayed low variability and a consistent dominance of needle biomass,while naturally regenerated beech showed greater variability and a higher proportion of stem biomass,reflecting stronger competition-driven vertical growth.Interspecific differences in total biomass were more pronounced when using tree height,with spruce generally exhibiting greater biomass than beech at equivalent heights.Overall,stem base diameter marginally outperformed tree height as a predictor of biomass.However,tree height-based models showed strong performance and are particularly suitable for integration with remote sensing applications.These findings can directly support forest managers and modellers in comparing regeneration methods and biomass estimation approaches for early-stage stand development,carbon accounting,and remote sensing calibration.展开更多
Brown spot(BS)of rice,caused by Bipolaris oryzae,is a serious concern that not only causes quantitative losses but also affects grain quality.To manage this disease,the use of resistant genetic sources and QTLs is an ...Brown spot(BS)of rice,caused by Bipolaris oryzae,is a serious concern that not only causes quantitative losses but also affects grain quality.To manage this disease,the use of resistant genetic sources and QTLs is an eco-friendly and economical option.In the current study,F_(3) progenies derived from a cross of susceptible parent PMS-18-B(PAU 10845-1-1-1-1)×resistant parent RP Path 77(RP patho-17)were used to identify potential QTLs linked to BS resistance and to associate this resistance with a temporal spike in defense-related enzymes.展开更多
BACKGROUND While varices and variceal bleeds are well-known and feared complications of advanced cirrhosis and portal hypertension,omental variceal bleed are a rare sequala even in patients with known esophageal or ga...BACKGROUND While varices and variceal bleeds are well-known and feared complications of advanced cirrhosis and portal hypertension,omental variceal bleed are a rare sequala even in patients with known esophageal or gastric varices.While rare,omental varices pose a risk for hemoperitoneum if ruptured,which is a lifethreatening complication with high mortality rates despite surgical intervention.CASE SUMMARY This report reviews the case of a patient 36-year-old female with alcohol related cirrhosis decompensated by ascites,but no history of varices admitted for hemorrhagic shock from spontaneous rupture of omental varices requiring emergency surgery.She underwent the first documented successful orthotopic liver transplantation the same admission.CONCLUSION This case report and literature review stresses the importance of early consideration and identification of intraabdominal variceal sources in cirrhotic patients with refractory shock.展开更多
Vaginal delivery is a fascinating physiological process,but also a high-risk process.Up to 85%–90%of vaginal deliveries lead to perineal trauma,with nearly 11%of severe perineal tearing.It is a common occurrence,espe...Vaginal delivery is a fascinating physiological process,but also a high-risk process.Up to 85%–90%of vaginal deliveries lead to perineal trauma,with nearly 11%of severe perineal tearing.It is a common occurrence,especially for first-time mothers.Computational childbirth plays an essential role in the prediction and prevention of these traumas,but fast personalization of the pelvis and floor muscles is challenging due to their anatomical complexity.This study introduces a novel shape-prediction-based personalization of the pelvis and floor muscles for perineal tearing management and childbirth simulation.300 subjects were selected from public Computed Tomography(CT)databases.The pelvic bone nmjmeshes were generated using a coarse-to-fine non-rigid mesh alignment procedure.The floor muscle meshes were personalized using the bone mesh deformation information.A feature-to-pelvic structure reconstruction pipeline was proposed,incorporating various strategies.Ten-fold cross-validation helped determine the optimal reconstruction strategy,regression method,and feature sizes.The mesh-to-mesh distance metric was employed for evaluating.The statistical shape relation-based strategy,coupled with multi-output ridge regression,was the optimal approach for pelvic structure reconstruction.With a feature set ranging from 3 to 38,the mean errors were 2.672 to 1.613 mm,and 3.237 to 1.415 mm in muscle attachment regions.The best-and worst-case predictions had errors of 1.227±0.959 mm and 2.900±2.309 mm,respectively.This study provides a novel approach to achieving fast personalized childbirth modeling and simulation for perineal tearing management.展开更多
Novel insights into complex biological processes very often critically depend on the establishment of new potent read-out tools and improved protocols.A lot has been learned over the past four decades on physiological...Novel insights into complex biological processes very often critically depend on the establishment of new potent read-out tools and improved protocols.A lot has been learned over the past four decades on physiological functions and,importantly,disease-related roles of the prion protein(PrP),a relatively broadly expressed membrane-anchored glycoprotein with high levels in several cell types of the nervous and immune system and with well-established key roles in different progressive and fatal neurodegenerative protein misfolding diseases(proteopathies).展开更多
基金National Natural Science Foundation of China(52175237)。
文摘The key parameters that characterize the morphological quality of multi-layer and multi-pass metal laser deposited parts are the surface roughness and the error between the actual printing height and the theoretical model height.The Taguchi method was employed to establish the correlations between process parameter combinations and multi-objective characterization of metal deposition morphology(height error and roughness).Results show that using the signal-to-noise ratio and grey relational analysis,the optimal parameter combination for multi-layer and multi-pass deposition is determined as follows:laser power of 800 W,powder feeding rate of 0.3 r/min,step distance of 1.6 mm,and scanning speed of 20 mm/s.Subsequently,a Genetic Bayesian-back propagation(GB-BP)network is constructed to predict multi-objective responses.Compared with the traditional back propagation network,the GB-back propagation network improves the prediction accuracy of height error and surface roughness by 43.14%and 71.43%,respectively.This network can accurately predict the multi-objective characterization of morphological quality of multi-layer and multi-pass metal deposited parts.
文摘The year 2026 marks the 70th anniversary of the establishment of diplomatic relations between China and African countries.It also marks the launch of the China-Africa Year of People-to-People Exchanges.At this pivotal juncture linking past achievements with future development,Wang Yi,member of the Political Bureau of the Communist Party of China Central Committee and foreign minister,continued the longstanding diplomatic tradition under which the Chinese foreign minister makes Africa the destination of the first overseas visit of the year,a practice upheld for 36 consecutive years,underscoring the stability,continuity and sincerity of China’s policy towards Africa.
基金supported by the National Natural Science Foundation of China(No.31600316)the Sichuan Science and Technology Program(2023NSFSC0198)。
文摘Understory bryophytes play unique and disproportionately important roles in water retention,biogeochemical cycling,and biodiversity conservation,and serve as bioindicators of environmental health in forest ecosystems.However,biogeographical research on the biomass of forest bryophytes is inadequately studied and has been limited to elevational gradients.We conducted a systematic cross-regional survey of bryophyte biomass across 413 forest sites in Sichuan Province,China.We analyzed how each environmental variable,including climatic and atmospheric factors,overstory covers,and soil nutrients,relates to bryophyte biomass and quantified their relative contributions.The results indicate that,largely similar to previous local investigations and experiments,at a large scale,bryophytes are abundant in forests with lower temperature,nitrogen deposition,vapor pressure deficit,and tree and herb covers,as well as higher light availability.Moreover,bryophyte biomass is positively associated with soil carbon and nitrogen content.These environmental variables are closely related and jointly influence bryophyte biomass,with mean annual temperature being the most significant factor(accounting for 83%of the relative contribution).The biogeographical patterns of bryophyte biomass contribute to deepening our understanding of their adaptations to multiple environmental variables and enable us to predict their responses to global climate change.These patterns also provide essential evidence for establishing more accurate terrestrial vegetation ecosystem models.
文摘On the threshold of 55 years of diplomatic relations,Cyprus and China stand to gain significantly by deepening their cooperation in trade,tourism,and green technology,guided by mutual respect and shared principles.WITH a population of approximately one million,Cyprus is a small country compared to China,which is home to more than 1.4 billion people.
基金supported by the National Natural Science Foundation of China(Grant Nos.42407595&41630753)the National Key Research and Development Program of China(Grant No.2022YFF0801501).
文摘The quantitative relationship between modern pollen and vegetation provides a critical foundation for reconstructing past vegetation,with relative pollen productivity(RPP)serving as a key calibration parameter.However,in subtropical evergreen broadleaved forests(SEBFs)in China,RPP studies remain scarce,and the impact of human disturbances on RPP estimates has yet to be adequately assessed,limiting the accuracy of quantitative palaeovegetation reconstructions.This study was conducted in Dinghu Mountain Nature Reserve and its surrounding areas in Zhaoqing,Guangdong Province,and included 31 sampling sites.We performed pollen analysis alongside detailed vegetation surveys and utilized ERV submodel 2 and Prentice’s model to estimate the RPP of 9 common plant taxa in the southern SEBFs.There was a particular focus on evaluating the interference effects of bamboo plantations on the estimation of RPP.The results indicate that bamboo within the family Poaceae contributes minimally to surface soil Poaceae pollen because of its unique flowering characteristics,such as long flowering cycles and monocarpic reproduction.The incorporation of bamboo into the Poaceae vegetation coverage in the analysis led to excessively high RPP values for the other taxa.When bamboo coverage was removed from the Poaceae family,the recalculated RPP values aligned closely with those reported in previous studies.The RPP values,ranked from highest to lowest,were as follows:Castanopsis(12.33±0.03)>Araliaceae(1.60±0.03)>Mallotus(1.53±0.26)>Pinus(1.47±0.03)>Rosaceae(1.07±0.02)>Poaceae(1±0)>Euphorbiaceae(0.44±0.03)>Anacardiaceae(0.26±0.03)>Theaceae(0.15±0).Notably,the RPP values for Mallotus,Araliaceae,Theaceae,and Euphorbiaceae represent the first estimates for China’s subtropical region.Differences between certain RPP estimates and those of previous studies may be attributed to factors such as species composition,vegetation structure,and model selection.The findings of this study highlight that due to the widespread distribution of artificial bamboo forests in China’s subtropical regions,future RPP studies should carefully consider the influence of Poaceae.This consideration is essential for improving the accuracy of the application of fossil pollen for quantitative paleo-vegetation reconstruction in these regions.
基金the National Natural Science Foundation of China (Nos. 52071179, 52271033)the Key Program of National Natural Science Foundation of China (No. 51931003)+2 种基金the Natural Science Foundation of Jiangsu Province, China (No. BK20221493)the Jiangsu Province Leading Edge Technology Basic Research Major Project, China (No. BK20222014)the Foundation of “Qinglan Project” for Colleges and Universities in Jiangsu Province, China。
文摘The composition−property relationship of 18 quaternary high entropy diborides(HEBs)consisting of boron and IVB,VB and VIB transition metals(TM)was investigated using first-principles calculations.A valence electron concentration−relative electronegativity(VEC−REN)composite descriptor was developed to effectively predict the mechanical properties of HEBs.The results demonstrate that with a fixed VEC,the rise of the REN makes HEBs harder but more brittle when the electronegativity of doped TM atoms is lower than that of boron atoms.However,HEBs become softer and more ductile as REN increases if the doped TM atoms have higher electronegativity than boron atoms.The VEC−REN composite descriptor can accurately classify and predict the mechanical properties of HEBs with different components,which provides important theoretical guidance for the rapid design and development of novel high-entropy ceramic materials.
基金support to this study from the National Natural Science Foundation of China,NSFC(Grant No.52278367)The Belt and Road Special Foundation of the National Key Laboratory ofWater Disaster Prevention(Grant No.2024nkms08).
文摘The stress-strain behavior of calcareous sand is significantly influencedby particle breakage(B)and initial relative density(Dri),but few constitutive models consider their combined effects.To bridge this gap,we conducted a series of triaxial tests on calcareous sand with varying Dri and stress paths,examining particle breakage and critical state behavior.Key findingsinclude:(1)At a constant stress ratio(η),B follows a hyperbolic relationship with mean effective stress(p'),and for a given p',B increases proportionally withη;(2)The critical state line(CSL)moves downward with increasing Dri,whereas the critical state friction angle(φcs)decreases with increasing B.Based on these findings,we propose a unifiedbreakage evolution model to quantify particle breakage in calcareous sand under various loading conditions.Integrating this model with the Normal Consolidation Line(NCL)and CSL equations,we successfully simulate the steepening of NCL and CSL slopes as B increases with the onset of particle breakage.Furthermore,we quantitatively evaluate the effect of B onφcs.Finally,within the framework of Critical State Soil Mechanics and Hypoplasticity theory,we develop a hypoplastic model incorporating B and Dri.The model is validated through strong agreement with experimental results across various initial relative densities,stress paths and drainage conditions.
基金supported by the Biological Breeding-National Science and Technology Major Project(2023ZD04071)the National Key Research and Development Program of China(2023YFF1000600)and the National Natural Science Foundation of China(32272084,32372089,and 31971887).
文摘Bread wheat(Triticum aestivum L.)is a staple hexaploid crop with numerous wild relatives.However,domestication and modern breeding have significantly narrowed its genetic diversity,diminishing its capacity to adapt to climate change.Wild relatives of wheat serve as a vital reservoir of genetic diversity,offering traits thatenhance its resistance to various biotic and abiotic stresses.Over recent decades,remarkable progress has been made in utilizing superior genes from wild relatives to bolster wheat's defenses against diseases and pests,though the exploration of genes conferring abiotic stress tolerance has lagged behind.In this review,we summarize key advancements in the utilization of wild relatives for wheat enhancement over the past century,emphasizing both theoretical and technological innovations.Furthermore,we evaluate the potential contributions of wild relatives to address production challenges posed by climate change.We also explore strategies for isolating superior genes and developing prebreeding germplasm to support the future development of climate-resilient wheat varieties.
基金Supported by the Science and Technology Program of Guizhou Province(Grant No.QKHJC QN[2025]362)the National Natural Science Foundation of China(Grant No.12361005).
文摘Loday introduced di-associative algebras and tri-associative algebras motivated by periodicity phenomena in algebraic K-theory.The purpose of this paper is to study the splittings of operations on di-associative algebras and tri-associative algebras.We introduce the notion of a quad-dendriform algebra,which is a splitting of a di-associative algebra.We show that a relative averaging operator on dendriform algebras gives rise to a quad-dendriform algebra.Furthermore,we introduce the notion of six-dendriform algebras,which are splittings of the tri-associative algebras,and demonstrate that homomorphic relative averaging operators induce six-dendriform algebras.
文摘The Almus Fault Zone(AFZ)is one of the major splay faults of the North Anatolian Fault Zone(NAFZ)and is important for understanding its tectonic features and assessing regional seismic hazards.This research presents the integration of morphometric indices to quantitatively assess the spatial variation of tectonic activity along the AFZ.The AFZ is an active fault with both strike-slip and normal fault components and consists of two main branches,Mercimekdağı-Çamdere Fault(MÇF)and Tokat Fault(TF)segments.This study aims to assess the relative tectonic activity of the AFZ using various morphometric indices,based on a 10 m resolution DEM,with the aid of ArcGIS and MATLAB software.For this purpose,morphometric indices such as hypsometric integral(HI:0.35-0.65),mountain front sinuosity(Smf:1.3-1.44),valley floor width-height ratio(Vf:0.15-2.28),asymmetry factor(AF:23-77),drainage basin shape(Bs:1.13-6.10)and normalized steepness index(ksn:1-498)were applied to 53 drainage basins.When the Smf and mean Vf indices results were evaluated,it was calculated that the uplift ratio of the region was more than 0.5 mm/yr.The spatial distribution of the relative tectonic activity(Iat)of the area was revealed by combining the obtained morphometric indices analysis results.According to the Iat result,it was concluded that the MercimekdağıÇamdere Fault and Tokat Fault segments have high tectonic activity,but the Mercimekdağı-Çamdere Fault segment has higher tectonic activity.The results obtained were also confirmed by field observations.This research provides valuable information for the evaluation of tectonic activity in drainage systems controlled by splay faults.
基金supported by a grant from the Central Level Public Welfare Research Institutes Basic Research Expenses of Chinese Academy of Medical Sciences(No.2023-RW320-05)。
文摘According to the 2024 global cancer data from GLOBOCAN,liver cancer ranks the 6th most common malignancy and the 3rd leading cause of cancer-related mortality worldwide[1].Among these cases,hepatocellular carcinoma(HCC)accounts for approximately 85%−90%[2,3].Its incidence and mortality rates remain persistently high worldwide.However,China has the highest incidence and mortality rates of the disease in the world[4].And the majority of patients are diagnosed at intermediate or advanced stages.Thus,identifying novel tumor biomarkers for early detection and implementing precision therapy has long been a key focus of research.
文摘Educational cooperation,as the cornerstone and vanguard of people-to-people exchanges and practical cooperation between China and Africa,holds irreplaceable strategic significance for enhancing the quality of Africa's human capital and accelerating its structural transformation and modernization process.This paper employs“demand–supply–adaptation”as its core analytical framework and aims to systematically explore how the educational cooperation between China and Africa can serve Africa's goal of modernization more precisely and effectively.First,through reviewing and analyzing the domestic and international research literature,this paper clarifies the focus,paradigms,and shortcomings of existing research,identifying the knowledge contribution of this study.Second,utilizing detailed macro-level data,case studies,and comparative research methods,it comprehensively presents the multidimensional status,structural characteristics,and development trends of China–Africa educational cooperation in areas such as student exchanges,cooperative education,vocational and technical training,language and cultural exchange,and emerging digital education.This paper also deeply analyzes the pressing and specific demands placed on the education system by Africa's modernization development across key dimensions like economic diversification,industrialization,agricultural modernization,social governance upgrading,and digital transformation.Third,based on the cooperative principle of“Africa's needs and China's strengths,”this paper innovatively proposes systematic countermeasures and suggestions for constructing new,multi-level,high-quality,sustainable,and future-oriented pathways for China–Africa educational cooperation:(a)promoting the strategic focus of cooperation to extend from“hard infrastructure”support to empowering“soft infrastructure”;(b)deepening the integration of industry and education and school–enterprise collaboration to precisely align with Africa's industrial development needs;vigorously developing digital education and jointly building a smart education ecosystem to help Africa bridge the digital divide;(c)improving an evidence-based,third-party evaluation system for cooperative effectiveness and a full-process quality assurance system;and(d)promoting the collaborative participation of multiple actors including governments,schools,enterprises,think tanks,and social organizations to build a new cooperative pattern of coconstruction,co-governance,and shared benefits.
文摘Aging,mitochondria,and neurodegenerative diseases:Aging is often viewed as the buildup of changes that lead to the gradual transformations associated with getting older,along with a rising likelihood of disease and mortality.Although organis m-wide deterioration is observed during aging,organs with high metabolic demand,such as the brain,are more vulnerable.
基金supported by National Key Research and Development Program of China(Grants No.2022YFF0802401 and 2023YFF0806900)China Postdoctoral Science Foundation(Grants No.2023M743456,GZB20230740,and 2024T170908).
文摘1.Introduction In recent years,intensifying climate extremes have triggered a sharp increase in global natural disasters,over 90%attributable to water-related hazards,particularly floods(Hirabayashi et al.,2013).Over the past two decades,floods have inundated approximately 2.23 million km2 of land worldwide(Tellman et al.,2021),affecting over 250 million people and causing economic losses exceeding USD 651 billion(Devitt et al.,2023).Recent catastrophic floods in Pakistan,landslides in Indonesia,and dike breaches in China have intensified concerns over the effectiveness of current flood management strategies.
文摘British Prime Minister Keir Starmer’s visit to China underscores economic cooperation and strategic stability amid global uncertainties.U.K.Prime Minister Keir Starmer’s visit to China in January marks a significant shift of Britain toward a more pragmatic and stability-oriented approach in Sino-British relations.After years of political tensions and limited high-level engagement,this trip underscores London’s intent to rebuild ties based on mutual economic and strategic interests.
基金funded by the grant“EVA4.0”,No.Z.02.1.01/0.0/0.0/16_019/0000803 supported by OP RDE as well as by the projects APVV-19-0387,APVV-22-0056,and APVV-23-0293 from the Slovak Research and Development Agencyco-funded by the European Commission under the Horizon Europe Teaming for Excellence action+1 种基金project Ligno Silvagrant agreement No.101059552。
文摘This study investigated biomass allocation in young stands of European beech(Fagus sylvatica L.)and Norway spruce(Picea abies(L.)Karst.)across 31 forest sites in the Western Carpathians,Slovakia.A total of 541 trees aged 2–10 years,originating from natural regeneration and planting,were destructively sampled to quantify biomass in four components:foliage,branches,stems,and roots.Generalized non-linear least squares(GNLS)models with a weighing variance function outperformed log-transformed seemingly unrelated regression(SUR)models in terms of accuracy and robustness,especially for foliage and branch biomass.When using height as the predictor,SUR models tended to underestimate biomass in planted beech,leading to notable underprediction of aboveground and total biomass.Biomass allocation patterns varied significantly by species and regeneration origin.Using a non-linear system of equations and component ratio modelling,we found out that planted spruce displayed low variability and a consistent dominance of needle biomass,while naturally regenerated beech showed greater variability and a higher proportion of stem biomass,reflecting stronger competition-driven vertical growth.Interspecific differences in total biomass were more pronounced when using tree height,with spruce generally exhibiting greater biomass than beech at equivalent heights.Overall,stem base diameter marginally outperformed tree height as a predictor of biomass.However,tree height-based models showed strong performance and are particularly suitable for integration with remote sensing applications.These findings can directly support forest managers and modellers in comparing regeneration methods and biomass estimation approaches for early-stage stand development,carbon accounting,and remote sensing calibration.
基金supported by Punjab Agricultural University,Ludhiana,India,for providing the infrastructure and other facilities for conducting experiments.All other forms of support and financial assistance are duly acknowledged.
文摘Brown spot(BS)of rice,caused by Bipolaris oryzae,is a serious concern that not only causes quantitative losses but also affects grain quality.To manage this disease,the use of resistant genetic sources and QTLs is an eco-friendly and economical option.In the current study,F_(3) progenies derived from a cross of susceptible parent PMS-18-B(PAU 10845-1-1-1-1)×resistant parent RP Path 77(RP patho-17)were used to identify potential QTLs linked to BS resistance and to associate this resistance with a temporal spike in defense-related enzymes.
文摘BACKGROUND While varices and variceal bleeds are well-known and feared complications of advanced cirrhosis and portal hypertension,omental variceal bleed are a rare sequala even in patients with known esophageal or gastric varices.While rare,omental varices pose a risk for hemoperitoneum if ruptured,which is a lifethreatening complication with high mortality rates despite surgical intervention.CASE SUMMARY This report reviews the case of a patient 36-year-old female with alcohol related cirrhosis decompensated by ascites,but no history of varices admitted for hemorrhagic shock from spontaneous rupture of omental varices requiring emergency surgery.She underwent the first documented successful orthotopic liver transplantation the same admission.CONCLUSION This case report and literature review stresses the importance of early consideration and identification of intraabdominal variceal sources in cirrhotic patients with refractory shock.
基金funded by Vietnam National University Ho Chi Minh City(VNU-HCM)under grant number DS.C2025-28-06.
文摘Vaginal delivery is a fascinating physiological process,but also a high-risk process.Up to 85%–90%of vaginal deliveries lead to perineal trauma,with nearly 11%of severe perineal tearing.It is a common occurrence,especially for first-time mothers.Computational childbirth plays an essential role in the prediction and prevention of these traumas,but fast personalization of the pelvis and floor muscles is challenging due to their anatomical complexity.This study introduces a novel shape-prediction-based personalization of the pelvis and floor muscles for perineal tearing management and childbirth simulation.300 subjects were selected from public Computed Tomography(CT)databases.The pelvic bone nmjmeshes were generated using a coarse-to-fine non-rigid mesh alignment procedure.The floor muscle meshes were personalized using the bone mesh deformation information.A feature-to-pelvic structure reconstruction pipeline was proposed,incorporating various strategies.Ten-fold cross-validation helped determine the optimal reconstruction strategy,regression method,and feature sizes.The mesh-to-mesh distance metric was employed for evaluating.The statistical shape relation-based strategy,coupled with multi-output ridge regression,was the optimal approach for pelvic structure reconstruction.With a feature set ranging from 3 to 38,the mean errors were 2.672 to 1.613 mm,and 3.237 to 1.415 mm in muscle attachment regions.The best-and worst-case predictions had errors of 1.227±0.959 mm and 2.900±2.309 mm,respectively.This study provides a novel approach to achieving fast personalized childbirth modeling and simulation for perineal tearing management.
基金supported by the CJD Foundation,USA,the Alzheimer Forschung Initiative(AFI)e.V.,Germany,and Werner-Otto-Stiftung,Germany(all to HCA),ChinaScholarship Council(grant#202108080249 to FS)Deutsche Forschungsgemeinschaft(DFG)CRC877“Proteolysis as a regulatory event in pathophysiology”(project A12 to MG),Slovene Research and InnovationAgency(grant number P4-0176 to VCS).
文摘Novel insights into complex biological processes very often critically depend on the establishment of new potent read-out tools and improved protocols.A lot has been learned over the past four decades on physiological functions and,importantly,disease-related roles of the prion protein(PrP),a relatively broadly expressed membrane-anchored glycoprotein with high levels in several cell types of the nervous and immune system and with well-established key roles in different progressive and fatal neurodegenerative protein misfolding diseases(proteopathies).
