The dynamics of complex gene regulation systems can be simulated by the Gillespie algorithm. The classic Gillespie algorithm is appropriate to simulate a stochastic
This paper sets Chaihu Town, Zhongxiang City of Hubei Province as an example, analyzing the ecological and hydrological conditions of Chaihu Town, applying LID （low impact development） mode and putting forward the e...This paper sets Chaihu Town, Zhongxiang City of Hubei Province as an example, analyzing the ecological and hydrological conditions of Chaihu Town, applying LID （low impact development） mode and putting forward the ecological stormwater regulation system planning strategy which adapts to the development of small towns. The main conclusions are as follows： （1） The ＂three-low＂ development mode is put forward, which means low impact, low cost and low carbon, using this construction mode to minimize the ecological impact, relying on natural green space and water to achieve the function of rainstorm regulation; （2） Through the analysis and calculation of the local amount of precipitation, this paper scientifically calculates the required area of storage water and green space, taking the roads as trunks, green spaces as stems, water as veins, and building the green infrastructure system; （3） The author has been repairing and integrating the original drainage ditches of the planning area, replacing traditional rain drainage pipes, establishing ＂two-loop＂ water network system which aims at the detention and purification of rainwater, maximizing ecological benefit, economic benefit and landscape benefit.展开更多
After the new round of restructuring of Chinese telecom sector,it's pressing to formulate and implement asymmetric regulation policies so as to shape an effectively competitive market structure in a relatively sho...After the new round of restructuring of Chinese telecom sector,it's pressing to formulate and implement asymmetric regulation policies so as to shape an effectively competitive market structure in a relatively short term.This paper reviewed the asymmetric regulation policies and practices carried out in foreign telecom market,and then according to the specific situations of Chinese telecom market,proposed the principles and corresponding policies for establishing an asymmetric regulation system fit for Chinese telecom market.展开更多
This paper presents the solution of regulating the wind rate automatically by means of fuzzy control technology and implementing it with PLC (programmable logical controller) under the circumstance of many influence f...This paper presents the solution of regulating the wind rate automatically by means of fuzzy control technology and implementing it with PLC (programmable logical controller) under the circumstance of many influence factors, which exists in the axial flow fans wind rate regulation system during the process of mine ventilation, and has difficulty in modifying the mathematic model to obtain the satisfied result by normal control ways. According to this analysis, the intelligent and analytic treatment of fuzzy controller has been made and fuzzy control scheme involving self regulation divisor and intelligent integral has been deeply proposed. Test result shows that this system based on the scheme above is obviously prior to others in its responsibility such as high speed, overshoot, control precision and robustness. The system furnishes the great reliability of mine working safety and fans running efficiency.展开更多
Outlined the South African mine health and safety regulatory framework,in- cluding the roles of government,tripartite council,service agencies,mine enterprises, rescue stations and workers unions,analyzed the institut...Outlined the South African mine health and safety regulatory framework,in- cluding the roles of government,tripartite council,service agencies,mine enterprises, rescue stations and workers unions,analyzed the institutional structures of South African mine health and safety standardization,including the South African standard and specifi- cation systems and standard development processes,and characterized the South African mine health and safety standardization and regulation systems.Intended to provide some suggestions for the transformation and improvement of mine health and safety standardi- zation and regulation systems in China or in similar situations.展开更多
During electric vehicle(EV)-assisted grid frequency modulation,inconsistent state of charge(SOC)among EVs can result in overcharging and discharging of the batteries,affecting the stability of the electrical system.As...During electric vehicle(EV)-assisted grid frequency modulation,inconsistent state of charge(SOC)among EVs can result in overcharging and discharging of the batteries,affecting the stability of the electrical system.As a solution,this paper proposes a priority-based frequency regulation strategy for EVs.Firstly,models for the primary and secondary frequency regulation of EV-assisted power grids are established.Secondly,a consensus algorithm is used to construct a distributed com-munication system for EVs.Target SOC values are used to obtain a local frequency regulation priori-ty list.The list is used in an optimal control plan allowing individual EVs to participate in frequency regulation.Finally,a simulation of this strategy under several scenarios is conducted.The results indicate that the strategy ensures uniform SOC among the participating group of EVs,thereby avoi-ding overcharging and discharging of their batteries.It also reduces frequency fluctuations in the electrical system,making the system more robust compared with the frequency regulation strategy that is not priority-based.展开更多
Main Exhauster is one of the main equipment of sintering production. It needs to consume a lot of electricity. Therefore, the system＇ s reconstruction for energy-saving will effectively reduce electricity for the pro...Main Exhauster is one of the main equipment of sintering production. It needs to consume a lot of electricity. Therefore, the system＇ s reconstruction for energy-saving will effectively reduce electricity for the production. The paper takes an iron and steel enterprise that had successfully transformed the synchronous motors of main exhauster of sintering as an example, which describes the application of high-voltage variable frequency speed regulation system in main exhauster of Sintering, so as to provide a reference for other iron and steel enterprises.展开更多
In order to scientifically deal with the problems of less water and more sediment in the Yellow River and the uncoordinated relationship between water and sediment,it is necessary to establish a perfect water and sedi...In order to scientifically deal with the problems of less water and more sediment in the Yellow River and the uncoordinated relationship between water and sediment,it is necessary to establish a perfect water and sediment regulation system.Through the calculation of the sediment transport capacity of the Yellow River and the application of the water and sediment regulation system,it is found that the sediment transport efficiency of the Yellow River will increase with the increase of water flow,and there will be an obvious inflection point near the flat discharge.The joint regulation of the backbone reservoir group can discharge the large discharge close to the minimum flat discharge of the downstream river,which improves the sediment transport capacity of the river and alleviates the problem of sediment deposition.In this paper,through the introduction of the Yellow River water and sediment regulation project system,regulation indicators and mechanisms,the author discusses in detail the Yellow River water and sediment regulation scheme and its operation effect,hoping to provide help promote the improvement of the Yellow River governance effect.展开更多
Large-scale new energy grid connection leads to the weakening of the system frequency regulation capability,and the system frequency stability is facing unprecedented challenges.In order to solve rapid frequency fluct...Large-scale new energy grid connection leads to the weakening of the system frequency regulation capability,and the system frequency stability is facing unprecedented challenges.In order to solve rapid frequency fluctuation caused by new energy units,this paper proposes a new energy power system frequency regulation strategy with multiple units including the doubly-fed pumped storage unit(DFPSU).Firstly,based on the model predictive control(MPC)theory,the state space equations are established by considering the operating characteristics of the units and the dynamic behavior of the system;secondly,the proportional-differential control link is introduced to minimize the frequency deviation to further optimize the frequency modulation(FM)output of the DFPSU and inhibit the rapid fluctuation of the frequency;lastly,it is verified on theMatlab/Simulink simulation platform,and the results show that the model predictive control with proportional-differential control link can further release the FM potential of the DFPSU,increase the depth of its FM,effectively reduce the frequency deviation of the system and its rate of change,realize the optimization of the active output of the DFPSU and that of other units,and improve the frequency response capability of the system.展开更多
Alzheimer's disease,a progressively degenerative neurological disorder,is the most common cause of dementia in the elderly.While its precise etiology remains unclear,researchers have identified diverse pathologica...Alzheimer's disease,a progressively degenerative neurological disorder,is the most common cause of dementia in the elderly.While its precise etiology remains unclear,researchers have identified diverse pathological characteristics and molecular pathways associated with its progression.Advances in scientific research have increasingly highlighted the crucial role of non-coding RNAs in the progression of Alzheimer's disease.These non-coding RNAs regulate several biological processes critical to the advancement of the disease,offering promising potential as therapeutic targets and diagnostic biomarkers.Therefore,this review aims to investigate the underlying mechanisms of Alzheimer's disease onset,with a particular focus on microRNAs,long non-coding RNAs,and circular RNAs associated with the disease.The review elucidates the potential pathogenic processes of Alzheimer's disease and provides a detailed description of the synthesis mechanisms of the three aforementioned non-coding RNAs.It comprehensively summarizes the various non-coding RNAs that have been identified to play key regulatory roles in Alzheimer's disease,as well as how these noncoding RNAs influence the disease's progression by regulating gene expression and protein functions.For example,miR-9 targets the UBE4B gene,promoting autophagy-mediated degradation of Tau protein,thereby reducing Tau accumulation and delaying Alzheimer's disease progression.Conversely,the long non-coding RNA BACE1-AS stabilizes BACE1 mRNA,promoting the generation of amyloid-βand accelerating Alzheimer's disease development.Additionally,circular RNAs play significant roles in regulating neuroinflammatory responses.By integrating insights from these regulatory mechanisms,there is potential to discover new therapeutic targets and potential biomarkers for early detection and management of Alzheimer's disease.This review aims to enhance the understanding of the relationship between Alzheimer's disease and non-coding RNAs,potentially paving the way for early detection and novel treatment strategies.展开更多
China implemented its Action Plan of Air Pollution Prevention and Control(APAPPC)in 2013 as a major step in national air-quality management.This study treated the APAPPC as a quasi-experiment,drawing on the Grossman a...China implemented its Action Plan of Air Pollution Prevention and Control(APAPPC)in 2013 as a major step in national air-quality management.This study treated the APAPPC as a quasi-experiment,drawing on the Grossman and Cropper models,to examine how air pollution affected individual health capital and medical service demand.Using panel data from the China Health and Retirement Longitudinal Study for 2011,2013,2015,and 2018,the analysis applied a Heckman two-stage model and difference-in-differences estimation to identify the policy's effects on medical expenditure.The results showed that the APAPPC significantly reduced annual health spending,with stronger effects among women,older adults,and rural residents.The mechanism analysis indicated that the reduction in respiratory diseases played a key role.This study provides evidence that supports further airpollution control in China and offers useful insights for other developing countries.展开更多
Dear Editor,This letter focuses on the distributed cooperative regulation problem for a class of networked re-entrant manufacturing systems(RMSs).The networked system is structured with a three-tier architecture:the p...Dear Editor,This letter focuses on the distributed cooperative regulation problem for a class of networked re-entrant manufacturing systems(RMSs).The networked system is structured with a three-tier architecture:the production line,the manufacturing layer and the workshop layer.The dynamics of re-entrant production lines are governed by hyperbolic partial differential equations(PDEs)based on the law of mass conservation.展开更多
Amid ongoing global environmental change and the critical pursuit of sustainable development,human-environment systems are exhibiting increasingly complex dynamic evolutions and spatial relationships,underscoring an u...Amid ongoing global environmental change and the critical pursuit of sustainable development,human-environment systems are exhibiting increasingly complex dynamic evolutions and spatial relationships,underscoring an urgent need for innovative research frameworks.Integrated geography synthesizes physical geography,human geography,and geographic information science,providing key frameworks for understanding complex human-environment systems.This editorial proposes an emerging research framework for integrated geography—“Composite driving-System evolution-Coupling mechanism-Synergistic regulation(CSCS)”—based on key issues such as climate change,biodiversity loss,resource scarcity,and social-ecological interactions,which have been highlighted in both recent critical literature on human-environment systems and UN assessment reports.The framework starts with diverse composite driving forces,extends to the evolution of human-environment system structures,processes,and functions that these drivers induce,explores couplings within human-environment systems,and calls for regulation aimed at sustainable development in synergies.Major research frontiers include understanding the cascading“evolution-coupling”effects of shocks;measuring system resilience,thresholds,and safe and just operating space boundaries;clarifying linkage mechanisms across scales;and achieving synergistic outcomes for multi-objective sustainability.This framework will help promote the interdisciplinary integration and development of integrated geography,and provide geographical solutions for the global sustainable development agenda.展开更多
This study aims to develop an accurate calculation model of transmission torque and load-bearing capacity for hydro-viscous clutches(HVC)used in high-power vehicles,which is important to investigate the step-less spee...This study aims to develop an accurate calculation model of transmission torque and load-bearing capacity for hydro-viscous clutches(HVC)used in high-power vehicles,which is important to investigate the step-less speed regulation characteristics in a fan drive system.However,most of the existing models ignore the distribution differences of groove area along the radial direction,which may lead to significant deviations in calculating the mechanical property of friction pairs related to operating conditions and the engagement process.To fill this gap,a new calculation model for bearing capacity and frictional torque of friction pairs with different oil grooves is proposed,in which the traditional fixed contact area ratio coefficient for oil groove measurement is replaced by a more precise discrete micro-ring area ratio(DMAR)integration method.Then,a 32-degree-of-freedoms dynamic model of HVC at a fan drive system is established for the prediction of dynamic responses during speed regulation.Results show that friction pairs with different oil grooves have a direct influence on frictional torque and bearing capacity through the change of DMAR along the radial direction.The friction pairs with different groove structures have oscillation phenomena at the engagement steady-state boundary.Furthermore,a step-less speed regulation experimental setup is established to verify the correctness of the proposed model.It is demonstrated that the axial engagement force and the speed regulation curve predicted by the proposed method are in good agreement with the experimental data.The results could effectively predict the engagement dynamic characteristics.The numerical relationship among the structure parameters,the mechanical properties of friction pairs,and the speed regulation characteristics of the system are established through the proposed model,which lays a theoretical foundation for the structure design of friction plates and optimization of step-less speed regulation performance.展开更多
This paper investigates the issue of load disturbances in DC motor speed regulation systems.In response to the limited disturbance rejection capability of traditional PID controllers,a PID controller with feedforward ...This paper investigates the issue of load disturbances in DC motor speed regulation systems.In response to the limited disturbance rejection capability of traditional PID controllers,a PID controller with feedforward compensation is designed.The study first analyzes the dynamic impact mechanism of sudden load changes on motor speed,and then achieves precise control of the DC motor using PWM technology.Through comparative analysis of simulation and experimental results,the proposed feedforward-compens ated PID control demonstrates significant improvements in dynamic response speed,overshoot,and steady-state accuracy compared to traditional PID control.The findings indicate that the proposed control strategy effectively supp resses load disturbances,e nhances system stability and robustness,and offers valuable insights for practical engineering applications.展开更多
To enhance the frequency stability and lower the regulation mileage payment of a multiarea integrated energy system(IES)that supports the power Internet of Things(IoT),this paper proposes a data-driven cooperative met...To enhance the frequency stability and lower the regulation mileage payment of a multiarea integrated energy system(IES)that supports the power Internet of Things(IoT),this paper proposes a data-driven cooperative method for automatic generation control(AGC).The method consists of adaptive fractional-order proportional-integral(FOPI)controllers and a novel efficient integration exploration multiagent twin delayed deep deterministic policy gradient(EIE-MATD3)algorithm.The FOPI controllers are designed for each area based on the performancebased frequency regulation market mechanism.The EIE-MATD3 algorithm is used to tune the coefficients of the FOPI controllers in real time using centralized training and decentralized execution.The algorithm incorporates imitation learning and efficient integration exploration to obtain a more robust coordinated control strategy.An experiment on the four-area China Southern Grid(CSG)real-time digital system shows that the proposed method can improve the control performance and reduce the regulation mileage payment of each area in the IES.展开更多
In this article,a novel model-free coordinated optimal regulation design methodology is proposed for the rigidly connected dual permanent magnet synchronous motor(PMSM)system via adaptive dynamic programming(ADP).Firs...In this article,a novel model-free coordinated optimal regulation design methodology is proposed for the rigidly connected dual permanent magnet synchronous motor(PMSM)system via adaptive dynamic programming(ADP).First,we adopt the classical master-slave structure to maintain torque synchronization by virtue of field-oriented control.Then,a reducedorder model of the dual-PMSM system is established through the application of singular perturbation theory(SPT),which is of significance to decrease the learning time and computational complexity in the outer speed loop design.Afterwards,we design a coordinated adaptive optimal regulator in framework of ADP to drive the speed of girth gear asymptotic tracking the reference signal and accommodate the load torque disturbance,which is independent of the knowledge of model parameters of the system.According to SPT,we analyze the suboptimality,closed-loop stability,and robustness properties of the obtained controller under mild conditions.Finally,comprehensive experimental studies are provided to verify that the proposed control strategy can achieve the speed regulation and the torque synchronization,as well as ameliorate the transient response.展开更多
Four distinct coordination polymers(CPs)were successfully synthesized by altering solvent types and adjusting ligand concentrations,and their crystal structures were investigated.[Co(L)(FDCA)(H_(2)O)_(2)]·0.5H_(2...Four distinct coordination polymers(CPs)were successfully synthesized by altering solvent types and adjusting ligand concentrations,and their crystal structures were investigated.[Co(L)(FDCA)(H_(2)O)_(2)]·0.5H_(2)O(1)was synthesized as a 2D structure using Coas the metal source,methanol‑water(4∶6,V/V)as the solvent,and specific concentrations of 2,5‑furandicarboxylic acid(H_(2)FDCA)and 1,3,5‑triimidazole benzene(L).Adjusting to pure water and lowering the concentration of L yielded the 1D chain structure of[Co(HL)2(H_(2)O)_(2)](FDCA)_(2)·6H_(2)O(2).Using Cu(Ⅱ)as the metal source,methanol/water(9∶1,V/V)as the solvent,and specific concentrations of L and H2FDCA,the 1D chain structure of[Cu(L)(FDCA)(H_(2)O)]·2H_(2)O(3)was synthesized.Upon increasing the concentrations of L and H2FDCA,and switching the solvent to pure water,the 1D chain structure of[Cu(HL)_(2)(H_(2)O)_(2)](FDCA)_(2)·6H_(2)O(4)was obtained.This shows that changing the solvent and ligand concentrations can affect the structural changes of CPs.In addition,the solid‑state photoluminescence of CPs 1‑4 at room temperature was studied,and their morphological changes were observed via scanning electron microscopy.Density functional theory calculations revealed that the negative charge concentrates on the O and N atoms of the ligand,facilitating ligand‑metal ion coordination.CCDC:2403934,1;2403935,2;2403936,3;2403938,4.展开更多
Nanofiltration(NF) technology,with its capacity for nanoscale filtration and controllable selectivity,holds significant promise in diverse applications.However,the current upper bound of permeance and selectivity of N...Nanofiltration(NF) technology,with its capacity for nanoscale filtration and controllable selectivity,holds significant promise in diverse applications.However,the current upper bound of permeance and selectivity of NF membranes is intrinsically constrained by the morphology and structure of the polyamide(PA) selective layer.This issue arises because NF membranes typically exhibit relatively smooth nodular structures,which theoretically impede efficient water transport.In this study,we enhanced the formation of nanobubbles by synergistically regulating with surfactant and low temperatures,resulting in the fabrication of PA NF membranes with a crumpled morphology.We observed that lower temperatures promote enhanced gas solubility in the aqueous phase,facilitating increased nanobubble formation through the foaming effect of surfactant sodium dodecylbenzene sulfonate(SDBS).Consequently,this resulted in the creation of PA NF membranes with more crumpled structures and superior performance,with pure water permeance reaching 36.25 ± 0.42 L m^(-2)h^(-1)bar^(-1),representing an improvement of 14.47 L m^(-2)h^(-1)bar^(-1)compared to the control group.Additionally,it maintains a high Na_(2)SO_(4) rejection rate of97.00 % ± 0.58 %.The PA NF membranes produced by eliminating nanobubbles and free interfaces exhibited a smooth structure,whereas introducing nanobubbles(through Na HCO_(3) addition,N_(2) pressurization,and ultrasonication) resulted in the formation of crumpled membranes.This emphasized that the large amount of nanobubbles generated by SDBS and low temperature in the interfacial process played a critical role in shaping crumpled PA NF membranes and enhancing membrane performance.This approach has the potential to provide valuable insights into customizing the structural design of TFC PA NF membranes,contributing to further advancements in this field.展开更多
Flowering time is a critical agronomic trait with a profound effect on the productivity and adaptabillity of rapeseed(Brassica napus L.).Strategically advancing flowering time can reduce the risk of yield losses due t...Flowering time is a critical agronomic trait with a profound effect on the productivity and adaptabillity of rapeseed(Brassica napus L.).Strategically advancing flowering time can reduce the risk of yield losses due to extreme climatic conditions and facilitate the cultivation of subsequent crops on the same land,thereby enhancing overall agricultural efficiency.In this review,we synthesize current information on flowering time regulation in rapeseed through an integrated analysis of its genetic,hormonal,and environmental dimensions,emphasizing their crosstalk and implications for yield.We consolidate multi-omics evidence from population genetics,functional genomics,and systems biology to create a haplotype-based framework that overcomes the trade-off between flowering time and yield,providing support for the precision breeding of early-maturing cultivars.The insights presented here could inform future research on flowering time regulation and guide strategies for increasing rapeseed productivity.展开更多
文摘The dynamics of complex gene regulation systems can be simulated by the Gillespie algorithm. The classic Gillespie algorithm is appropriate to simulate a stochastic
文摘This paper sets Chaihu Town, Zhongxiang City of Hubei Province as an example, analyzing the ecological and hydrological conditions of Chaihu Town, applying LID （low impact development） mode and putting forward the ecological stormwater regulation system planning strategy which adapts to the development of small towns. The main conclusions are as follows： （1） The ＂three-low＂ development mode is put forward, which means low impact, low cost and low carbon, using this construction mode to minimize the ecological impact, relying on natural green space and water to achieve the function of rainstorm regulation; （2） Through the analysis and calculation of the local amount of precipitation, this paper scientifically calculates the required area of storage water and green space, taking the roads as trunks, green spaces as stems, water as veins, and building the green infrastructure system; （3） The author has been repairing and integrating the original drainage ditches of the planning area, replacing traditional rain drainage pipes, establishing ＂two-loop＂ water network system which aims at the detention and purification of rainwater, maximizing ecological benefit, economic benefit and landscape benefit.
文摘After the new round of restructuring of Chinese telecom sector,it's pressing to formulate and implement asymmetric regulation policies so as to shape an effectively competitive market structure in a relatively short term.This paper reviewed the asymmetric regulation policies and practices carried out in foreign telecom market,and then according to the specific situations of Chinese telecom market,proposed the principles and corresponding policies for establishing an asymmetric regulation system fit for Chinese telecom market.
文摘This paper presents the solution of regulating the wind rate automatically by means of fuzzy control technology and implementing it with PLC (programmable logical controller) under the circumstance of many influence factors, which exists in the axial flow fans wind rate regulation system during the process of mine ventilation, and has difficulty in modifying the mathematic model to obtain the satisfied result by normal control ways. According to this analysis, the intelligent and analytic treatment of fuzzy controller has been made and fuzzy control scheme involving self regulation divisor and intelligent integral has been deeply proposed. Test result shows that this system based on the scheme above is obviously prior to others in its responsibility such as high speed, overshoot, control precision and robustness. The system furnishes the great reliability of mine working safety and fans running efficiency.
文摘Outlined the South African mine health and safety regulatory framework,in- cluding the roles of government,tripartite council,service agencies,mine enterprises, rescue stations and workers unions,analyzed the institutional structures of South African mine health and safety standardization,including the South African standard and specifi- cation systems and standard development processes,and characterized the South African mine health and safety standardization and regulation systems.Intended to provide some suggestions for the transformation and improvement of mine health and safety standardi- zation and regulation systems in China or in similar situations.
基金Supported by the China Postdoctoral Science Foundation(No.2022M710039).
文摘During electric vehicle(EV)-assisted grid frequency modulation,inconsistent state of charge(SOC)among EVs can result in overcharging and discharging of the batteries,affecting the stability of the electrical system.As a solution,this paper proposes a priority-based frequency regulation strategy for EVs.Firstly,models for the primary and secondary frequency regulation of EV-assisted power grids are established.Secondly,a consensus algorithm is used to construct a distributed com-munication system for EVs.Target SOC values are used to obtain a local frequency regulation priori-ty list.The list is used in an optimal control plan allowing individual EVs to participate in frequency regulation.Finally,a simulation of this strategy under several scenarios is conducted.The results indicate that the strategy ensures uniform SOC among the participating group of EVs,thereby avoi-ding overcharging and discharging of their batteries.It also reduces frequency fluctuations in the electrical system,making the system more robust compared with the frequency regulation strategy that is not priority-based.
文摘Main Exhauster is one of the main equipment of sintering production. It needs to consume a lot of electricity. Therefore, the system＇ s reconstruction for energy-saving will effectively reduce electricity for the production. The paper takes an iron and steel enterprise that had successfully transformed the synchronous motors of main exhauster of sintering as an example, which describes the application of high-voltage variable frequency speed regulation system in main exhauster of Sintering, so as to provide a reference for other iron and steel enterprises.
文摘In order to scientifically deal with the problems of less water and more sediment in the Yellow River and the uncoordinated relationship between water and sediment,it is necessary to establish a perfect water and sediment regulation system.Through the calculation of the sediment transport capacity of the Yellow River and the application of the water and sediment regulation system,it is found that the sediment transport efficiency of the Yellow River will increase with the increase of water flow,and there will be an obvious inflection point near the flat discharge.The joint regulation of the backbone reservoir group can discharge the large discharge close to the minimum flat discharge of the downstream river,which improves the sediment transport capacity of the river and alleviates the problem of sediment deposition.In this paper,through the introduction of the Yellow River water and sediment regulation project system,regulation indicators and mechanisms,the author discusses in detail the Yellow River water and sediment regulation scheme and its operation effect,hoping to provide help promote the improvement of the Yellow River governance effect.
基金supported by the National Natural Science Foundation of China(Project No.52377082)the Scientific Research Program of Jilin Provincial Department of Education(Project No.JJKH20230123KJ).
文摘Large-scale new energy grid connection leads to the weakening of the system frequency regulation capability,and the system frequency stability is facing unprecedented challenges.In order to solve rapid frequency fluctuation caused by new energy units,this paper proposes a new energy power system frequency regulation strategy with multiple units including the doubly-fed pumped storage unit(DFPSU).Firstly,based on the model predictive control(MPC)theory,the state space equations are established by considering the operating characteristics of the units and the dynamic behavior of the system;secondly,the proportional-differential control link is introduced to minimize the frequency deviation to further optimize the frequency modulation(FM)output of the DFPSU and inhibit the rapid fluctuation of the frequency;lastly,it is verified on theMatlab/Simulink simulation platform,and the results show that the model predictive control with proportional-differential control link can further release the FM potential of the DFPSU,increase the depth of its FM,effectively reduce the frequency deviation of the system and its rate of change,realize the optimization of the active output of the DFPSU and that of other units,and improve the frequency response capability of the system.
文摘Alzheimer's disease,a progressively degenerative neurological disorder,is the most common cause of dementia in the elderly.While its precise etiology remains unclear,researchers have identified diverse pathological characteristics and molecular pathways associated with its progression.Advances in scientific research have increasingly highlighted the crucial role of non-coding RNAs in the progression of Alzheimer's disease.These non-coding RNAs regulate several biological processes critical to the advancement of the disease,offering promising potential as therapeutic targets and diagnostic biomarkers.Therefore,this review aims to investigate the underlying mechanisms of Alzheimer's disease onset,with a particular focus on microRNAs,long non-coding RNAs,and circular RNAs associated with the disease.The review elucidates the potential pathogenic processes of Alzheimer's disease and provides a detailed description of the synthesis mechanisms of the three aforementioned non-coding RNAs.It comprehensively summarizes the various non-coding RNAs that have been identified to play key regulatory roles in Alzheimer's disease,as well as how these noncoding RNAs influence the disease's progression by regulating gene expression and protein functions.For example,miR-9 targets the UBE4B gene,promoting autophagy-mediated degradation of Tau protein,thereby reducing Tau accumulation and delaying Alzheimer's disease progression.Conversely,the long non-coding RNA BACE1-AS stabilizes BACE1 mRNA,promoting the generation of amyloid-βand accelerating Alzheimer's disease development.Additionally,circular RNAs play significant roles in regulating neuroinflammatory responses.By integrating insights from these regulatory mechanisms,there is potential to discover new therapeutic targets and potential biomarkers for early detection and management of Alzheimer's disease.This review aims to enhance the understanding of the relationship between Alzheimer's disease and non-coding RNAs,potentially paving the way for early detection and novel treatment strategies.
基金Natural Science Foundation of Hubei Province(No.2025AFC041).
文摘China implemented its Action Plan of Air Pollution Prevention and Control(APAPPC)in 2013 as a major step in national air-quality management.This study treated the APAPPC as a quasi-experiment,drawing on the Grossman and Cropper models,to examine how air pollution affected individual health capital and medical service demand.Using panel data from the China Health and Retirement Longitudinal Study for 2011,2013,2015,and 2018,the analysis applied a Heckman two-stage model and difference-in-differences estimation to identify the policy's effects on medical expenditure.The results showed that the APAPPC significantly reduced annual health spending,with stronger effects among women,older adults,and rural residents.The mechanism analysis indicated that the reduction in respiratory diseases played a key role.This study provides evidence that supports further airpollution control in China and offers useful insights for other developing countries.
文摘Dear Editor,This letter focuses on the distributed cooperative regulation problem for a class of networked re-entrant manufacturing systems(RMSs).The networked system is structured with a three-tier architecture:the production line,the manufacturing layer and the workshop layer.The dynamics of re-entrant production lines are governed by hyperbolic partial differential equations(PDEs)based on the law of mass conservation.
基金supported by the National Natural Science Foundation of China(Grants No.W2412144,42271292)the 111 project,and the Fundamental Research Funds for the Central Universities of China.
文摘Amid ongoing global environmental change and the critical pursuit of sustainable development,human-environment systems are exhibiting increasingly complex dynamic evolutions and spatial relationships,underscoring an urgent need for innovative research frameworks.Integrated geography synthesizes physical geography,human geography,and geographic information science,providing key frameworks for understanding complex human-environment systems.This editorial proposes an emerging research framework for integrated geography—“Composite driving-System evolution-Coupling mechanism-Synergistic regulation(CSCS)”—based on key issues such as climate change,biodiversity loss,resource scarcity,and social-ecological interactions,which have been highlighted in both recent critical literature on human-environment systems and UN assessment reports.The framework starts with diverse composite driving forces,extends to the evolution of human-environment system structures,processes,and functions that these drivers induce,explores couplings within human-environment systems,and calls for regulation aimed at sustainable development in synergies.Major research frontiers include understanding the cascading“evolution-coupling”effects of shocks;measuring system resilience,thresholds,and safe and just operating space boundaries;clarifying linkage mechanisms across scales;and achieving synergistic outcomes for multi-objective sustainability.This framework will help promote the interdisciplinary integration and development of integrated geography,and provide geographical solutions for the global sustainable development agenda.
基金Supported by the National Natural Science Foundation of China(Grant Nos.52475089,52035002)National Key Research and Development Program of China(Grant No.2021YFB2011400)the Chongqing Natural Science Foundation(Grant No.CSTB2022NSCQ-MSX1243).
文摘This study aims to develop an accurate calculation model of transmission torque and load-bearing capacity for hydro-viscous clutches(HVC)used in high-power vehicles,which is important to investigate the step-less speed regulation characteristics in a fan drive system.However,most of the existing models ignore the distribution differences of groove area along the radial direction,which may lead to significant deviations in calculating the mechanical property of friction pairs related to operating conditions and the engagement process.To fill this gap,a new calculation model for bearing capacity and frictional torque of friction pairs with different oil grooves is proposed,in which the traditional fixed contact area ratio coefficient for oil groove measurement is replaced by a more precise discrete micro-ring area ratio(DMAR)integration method.Then,a 32-degree-of-freedoms dynamic model of HVC at a fan drive system is established for the prediction of dynamic responses during speed regulation.Results show that friction pairs with different oil grooves have a direct influence on frictional torque and bearing capacity through the change of DMAR along the radial direction.The friction pairs with different groove structures have oscillation phenomena at the engagement steady-state boundary.Furthermore,a step-less speed regulation experimental setup is established to verify the correctness of the proposed model.It is demonstrated that the axial engagement force and the speed regulation curve predicted by the proposed method are in good agreement with the experimental data.The results could effectively predict the engagement dynamic characteristics.The numerical relationship among the structure parameters,the mechanical properties of friction pairs,and the speed regulation characteristics of the system are established through the proposed model,which lays a theoretical foundation for the structure design of friction plates and optimization of step-less speed regulation performance.
文摘This paper investigates the issue of load disturbances in DC motor speed regulation systems.In response to the limited disturbance rejection capability of traditional PID controllers,a PID controller with feedforward compensation is designed.The study first analyzes the dynamic impact mechanism of sudden load changes on motor speed,and then achieves precise control of the DC motor using PWM technology.Through comparative analysis of simulation and experimental results,the proposed feedforward-compens ated PID control demonstrates significant improvements in dynamic response speed,overshoot,and steady-state accuracy compared to traditional PID control.The findings indicate that the proposed control strategy effectively supp resses load disturbances,e nhances system stability and robustness,and offers valuable insights for practical engineering applications.
基金upported by National Natural Science Foundation of China(52307118).
文摘To enhance the frequency stability and lower the regulation mileage payment of a multiarea integrated energy system(IES)that supports the power Internet of Things(IoT),this paper proposes a data-driven cooperative method for automatic generation control(AGC).The method consists of adaptive fractional-order proportional-integral(FOPI)controllers and a novel efficient integration exploration multiagent twin delayed deep deterministic policy gradient(EIE-MATD3)algorithm.The FOPI controllers are designed for each area based on the performancebased frequency regulation market mechanism.The EIE-MATD3 algorithm is used to tune the coefficients of the FOPI controllers in real time using centralized training and decentralized execution.The algorithm incorporates imitation learning and efficient integration exploration to obtain a more robust coordinated control strategy.An experiment on the four-area China Southern Grid(CSG)real-time digital system shows that the proposed method can improve the control performance and reduce the regulation mileage payment of each area in the IES.
基金supported by the National Natural Science Foundation of China(62073327,62403467,62373090,62273350,62521001)the Natural Science Foundation of Jiangsu Province(BK20241635)+2 种基金the Postdoctoral Fellowship Program of China Postdoctoral Science Foundation(CPSF)(GZB20240827)Jiangsu Funding Program for Excellent Postdoctoral Talent(2024ZB604)the China Postdoctoral Science Foundation(2024M763545,2025T054ZGMK).
文摘In this article,a novel model-free coordinated optimal regulation design methodology is proposed for the rigidly connected dual permanent magnet synchronous motor(PMSM)system via adaptive dynamic programming(ADP).First,we adopt the classical master-slave structure to maintain torque synchronization by virtue of field-oriented control.Then,a reducedorder model of the dual-PMSM system is established through the application of singular perturbation theory(SPT),which is of significance to decrease the learning time and computational complexity in the outer speed loop design.Afterwards,we design a coordinated adaptive optimal regulator in framework of ADP to drive the speed of girth gear asymptotic tracking the reference signal and accommodate the load torque disturbance,which is independent of the knowledge of model parameters of the system.According to SPT,we analyze the suboptimality,closed-loop stability,and robustness properties of the obtained controller under mild conditions.Finally,comprehensive experimental studies are provided to verify that the proposed control strategy can achieve the speed regulation and the torque synchronization,as well as ameliorate the transient response.
文摘Four distinct coordination polymers(CPs)were successfully synthesized by altering solvent types and adjusting ligand concentrations,and their crystal structures were investigated.[Co(L)(FDCA)(H_(2)O)_(2)]·0.5H_(2)O(1)was synthesized as a 2D structure using Coas the metal source,methanol‑water(4∶6,V/V)as the solvent,and specific concentrations of 2,5‑furandicarboxylic acid(H_(2)FDCA)and 1,3,5‑triimidazole benzene(L).Adjusting to pure water and lowering the concentration of L yielded the 1D chain structure of[Co(HL)2(H_(2)O)_(2)](FDCA)_(2)·6H_(2)O(2).Using Cu(Ⅱ)as the metal source,methanol/water(9∶1,V/V)as the solvent,and specific concentrations of L and H2FDCA,the 1D chain structure of[Cu(L)(FDCA)(H_(2)O)]·2H_(2)O(3)was synthesized.Upon increasing the concentrations of L and H2FDCA,and switching the solvent to pure water,the 1D chain structure of[Cu(HL)_(2)(H_(2)O)_(2)](FDCA)_(2)·6H_(2)O(4)was obtained.This shows that changing the solvent and ligand concentrations can affect the structural changes of CPs.In addition,the solid‑state photoluminescence of CPs 1‑4 at room temperature was studied,and their morphological changes were observed via scanning electron microscopy.Density functional theory calculations revealed that the negative charge concentrates on the O and N atoms of the ligand,facilitating ligand‑metal ion coordination.CCDC:2403934,1;2403935,2;2403936,3;2403938,4.
基金the National Natural Science Foundation of China (Nos.52430001,52470091,52200108) for the financial support。
文摘Nanofiltration(NF) technology,with its capacity for nanoscale filtration and controllable selectivity,holds significant promise in diverse applications.However,the current upper bound of permeance and selectivity of NF membranes is intrinsically constrained by the morphology and structure of the polyamide(PA) selective layer.This issue arises because NF membranes typically exhibit relatively smooth nodular structures,which theoretically impede efficient water transport.In this study,we enhanced the formation of nanobubbles by synergistically regulating with surfactant and low temperatures,resulting in the fabrication of PA NF membranes with a crumpled morphology.We observed that lower temperatures promote enhanced gas solubility in the aqueous phase,facilitating increased nanobubble formation through the foaming effect of surfactant sodium dodecylbenzene sulfonate(SDBS).Consequently,this resulted in the creation of PA NF membranes with more crumpled structures and superior performance,with pure water permeance reaching 36.25 ± 0.42 L m^(-2)h^(-1)bar^(-1),representing an improvement of 14.47 L m^(-2)h^(-1)bar^(-1)compared to the control group.Additionally,it maintains a high Na_(2)SO_(4) rejection rate of97.00 % ± 0.58 %.The PA NF membranes produced by eliminating nanobubbles and free interfaces exhibited a smooth structure,whereas introducing nanobubbles(through Na HCO_(3) addition,N_(2) pressurization,and ultrasonication) resulted in the formation of crumpled membranes.This emphasized that the large amount of nanobubbles generated by SDBS and low temperature in the interfacial process played a critical role in shaping crumpled PA NF membranes and enhancing membrane performance.This approach has the potential to provide valuable insights into customizing the structural design of TFC PA NF membranes,contributing to further advancements in this field.
基金supported by the National Key Research and Development Program of China(2022YFD1200400)the National Natural Science Foundation of China(32272111)+4 种基金Special fund for youth team of the Southwest Universities(SWU-XJPY202306)Chongqing Natural Science Foundation(CSTB2024NSCQLZX0012)Modern Agro-industry Technology Research System(CARS-12)Chongqing Modern Agricultural Industry Technology System(COMAITS202504)Biological Breeding-National Science and Technology Major Project(2022ZD04008).We sincerely appreciate the Plant Editors team for English language editing of the manuscript,which significantly improved its clarity and overall quality.
文摘Flowering time is a critical agronomic trait with a profound effect on the productivity and adaptabillity of rapeseed(Brassica napus L.).Strategically advancing flowering time can reduce the risk of yield losses due to extreme climatic conditions and facilitate the cultivation of subsequent crops on the same land,thereby enhancing overall agricultural efficiency.In this review,we synthesize current information on flowering time regulation in rapeseed through an integrated analysis of its genetic,hormonal,and environmental dimensions,emphasizing their crosstalk and implications for yield.We consolidate multi-omics evidence from population genetics,functional genomics,and systems biology to create a haplotype-based framework that overcomes the trade-off between flowering time and yield,providing support for the precision breeding of early-maturing cultivars.The insights presented here could inform future research on flowering time regulation and guide strategies for increasing rapeseed productivity.
