Background There have been numerous intervention studies focusing on the development of preterm infants,but there has been limited investigation into the home environment as a determinant of developmental outcomes in ...Background There have been numerous intervention studies focusing on the development of preterm infants,but there has been limited investigation into the home environment as a determinant of developmental outcomes in preterm infants.The aspects and extent to which the home environment affects the early(18 months corrected age)neuropsychological development of preterm infants are still unclear.Aims This study aimed to analyse the effect of the home environment on the neuropsychiatric development of preterm infants at 18 months corrected age after discharge from the neonatal intensive care unit(NICU).It also sought to provide a basis for promoting neuropsychiatric development among preterm infants by improving the home environment.Methods In this retrospective cross-sectional study,275 preterm infants born between January 2019 and January 2022 were followed up for systematic management after discharge from the NICU at Shanghai Children's Hospital.The Home Nurture Environment Questionnaire was used to assess the home environment of the infants and analyse its impact on the developmental quotient(evaluated by the Gesell Developmental Scale)and the rate of developmental delays at 18 months corrected age.Results A total of 41.454%of the infants were extremely preterm.The developmental quotient scores at 18 months corrected age were in the middle of the scale.The language domain had the highest rate of developmental delay(46.182%),followed by the adaptive domain(37.091%).Multiple logistic regression analyses showed that compared with infants in supportive home environments,infants with moderate/unsupportive home environments had significantly elevated risks of development delay:2.162-fold for global(odds ratio(OR)2.162,95% confidence interval(Cl)1.274 to 3.665,p=0.004),2.193-fold for fine motor(OR 2.193,95%CI 1.161 to 4.140,p=0.016),2.249-fold for language(0R 2.249,95%CI 1.336 to 3.786,p=0.002)and 2.042-fold for personal-social(OR 2.042,95%CI 1.149 to 3.628,p=0.015).Conclusions A supportive home environment is a crucial protective factor for the neuropsychological development of preterm infants.It is associated with higher developmental quotient scores and protects against neuropsychiatric delays.Incorporating evaluation and continuous improvement of the home environment into the management framework for preterm infants to promote optimal neurodevelopment is essential.展开更多
BACKGROUND The effect of the number of lymph node dissections(LNDs)during radical resection for colorectal cancer(CRC)on overall survival(OS)remains controver-sial.AIM To investigate the association between the number...BACKGROUND The effect of the number of lymph node dissections(LNDs)during radical resection for colorectal cancer(CRC)on overall survival(OS)remains controver-sial.AIM To investigate the association between the number of LNDs and OS in patients with tumor node metastasis(TNM)stage Ⅰ–Ⅱ CRC undergoing radical resection.METHODS Patients who underwent radical resection for CRC at a single-center hospital between January 2011 and December 2021 were retrospectively analyzed.Cox regression analyses were performed to identify the independent predictors of OS at different T stages.RESULTS A total of 2850 patients who underwent laparoscopic radical resection for CRC were enrolled.At stage T1,age[P<0.01,hazard ratio(HR)=1.075,95%confidence interval(CI):1.019-1.134]and tumour size(P=0.021,HR=3.635,95%CI:1.210-10.917)were independent risk factors for OS.At stage T2,age(P<0.01,HR=1.064,95%CI:1.032-1.098)and overall complications(P=0.012,HR=2.297,95%CI:1.200-4.397)were independent risk factors for OS.At stage T3,only age(P<0.01,HR=1.047,95%CI:1.027-1.066)was an independent risk factor for OS.At stage T4,age(P<0.01,HR=1.057,95%CI:1.039-1.075)and body mass index(P=0.034,HR=0.941,95%CI:0.890-0.995)were independent risk factors for OS.However,there was no association between LNDs and OS in stages Ⅰ and Ⅱ.CONCLUSION The number of LDNs did not affect the survival of patients with TNM stages Ⅰ and Ⅱ CRC.Therefore,insufficient LNDs should not be a cause for alarm during the surgery.展开更多
With the development of stereoscopic technology, more attention is attracted on the stereoscopic three-dimensional(S3 D) content and service, and researches on images and videos have emerged in large numbers. This pap...With the development of stereoscopic technology, more attention is attracted on the stereoscopic three-dimensional(S3 D) content and service, and researches on images and videos have emerged in large numbers. This paper focuses mainly on visual comfort affected by characteristics of disparity for multiple objects. To find the relationship between disparity distribution and visual comfort perception, several subject evaluation experiments are done. The study contains two spatial distribution types of disparity: 1) only one of the foreground objects has zero disparity; 2) one of the foreground objects has positive disparity, while the other one has negative disparity. The experimental results and relative regression analysis provide appropriate relationship between disparity distribution and visual comfort for both conditions, which is significant to meet the applicant field in S3 D content acquisition, display adjustment and quality evaluation.展开更多
An analysis of the influencing factors and mechanism of tourist revisiting willingness by adopting the multiple regressionmodel based on the survey data obtained from 581 valid questionnaires concerning Kaiping Diaolo...An analysis of the influencing factors and mechanism of tourist revisiting willingness by adopting the multiple regressionmodel based on the survey data obtained from 581 valid questionnaires concerning Kaiping Diaolou and Villages reveals that the maininfluencing factors of revisit intention are:tourist spot image,cognitive attitude,tourists'expectation and satisfaction.Of the fourmain factors,tourists'cognitive attitude is the direct influence factor,and the image of the sites and tourists'expectation indirectlyinfluence the revisit intention through tourists'satisfaction.This research result provides a new approach to the market developmentfor the heritage villages.展开更多
Objective To evaluate the factors affecting the incidence of intrahepatic venovenous shunt(IVVS)in patients with cirrhosis and its impact on hepatic venous pressure gradient(HVPG).Methods A retrospective analysis was ...Objective To evaluate the factors affecting the incidence of intrahepatic venovenous shunt(IVVS)in patients with cirrhosis and its impact on hepatic venous pressure gradient(HVPG).Methods A retrospective analysis was performed on the data of patients with liver cirrhosis who received HVPG measurement in Nanjing Drum Tower Hospital from April 2013 to March 2022.Univariate and multivariate regression analyses were used to investigate the incidence rate and risk factors of IVVS and its impact on HVPG.The t-test and rank-sum test were used for the measurement data,and the x?test was used for the count data.Results A total of 242 cases with cirrhosis were included in the statistical analysis,including 54(22.3%)with IVVS and 188(77.7%)without IVVS.There was a statistically significant difference(P<0.05)in prothrombin time(PT),HVPG,and splenectomy history between the two groups of patients'baseline data(all P<0.05).The multiple logistic regression analysis results showed that PT was an independent risk factor for the occurrence of IVVS(P<0.05),and patients combined with IVVS had lower HVPG values[(17.58±5.57)mmHg vs.(11.92±5.38)mmHg,1 mmHg=0.133 kPa;t=6.623,P<0.001].Conclusion Patients with liver cirrhosis have a high incidence rate of IVVS,which is closely associated with a low prothrombin time.Additionally,patients combined with IVVS have low HVPG values,which affect its accuracy.展开更多
Background： Animal models of asphyxiation cardiac arrest （ACA） are frequently used in basic research to mirror the clinical course of cardiac arrest （CA）. The rates of the return of spontaneous circulation （ROSC...Background： Animal models of asphyxiation cardiac arrest （ACA） are frequently used in basic research to mirror the clinical course of cardiac arrest （CA）. The rates of the return of spontaneous circulation （ROSC） inACA animal models are lower than those from studies that have utilized ventricular fibrillation （VF） animal models. The purpose of this study was to characterize the factors associated with the ROSC in the ACA porcine model. Methods： Forty-eight healthy miniature pigs underwent endotracheal tube clamping to induce CA. Once induced, CA was maintained untreated for a period of 8 min. Two minutes following the initiation of cardiopulmonary resuscitation （CPR）, defibrillation was attempted until ROSC was achieved or the animal died. To assess the factors associated with ROSC in this CA model, logistic regression analyses were performed to analyze gender, the time of preparation, the amplitude spectrum area （AMSA） from the beginning of CPR and the pH at the beginning of CPR. A receiver-operating characteristic （ROC） curve was used to evaluate the predictive value ofAMSA for ROSC. Results： ROSC was only 52.1% successful in this ACA porcine model. The multivariate logistic regression analyses revealed that ROSC significantly depended on the time of preparation, AMSA at the beginning of CPR and pH at the beginning of CPR. The area under the ROC curve in for AMSA at the beginning of CPR was 0.878 successful in predicting ROSC （95% confidence intervals： 0.773-0.983）, and the optimum cut-offvalue was 15.62 （specificity 95.7% and sensitivity 80.0%）. Conclusions： The time of preparation, AMSA and the pH at the beginning of CPR were associated with ROSC in this ACA porcine model. AMSA also predicted the likelihood of ROSC in this ACA animal model.展开更多
基金funded by Shanghai Municipal Health and Wellness Commission Health Industry Clinical Research Special Project(202140299).
文摘Background There have been numerous intervention studies focusing on the development of preterm infants,but there has been limited investigation into the home environment as a determinant of developmental outcomes in preterm infants.The aspects and extent to which the home environment affects the early(18 months corrected age)neuropsychological development of preterm infants are still unclear.Aims This study aimed to analyse the effect of the home environment on the neuropsychiatric development of preterm infants at 18 months corrected age after discharge from the neonatal intensive care unit(NICU).It also sought to provide a basis for promoting neuropsychiatric development among preterm infants by improving the home environment.Methods In this retrospective cross-sectional study,275 preterm infants born between January 2019 and January 2022 were followed up for systematic management after discharge from the NICU at Shanghai Children's Hospital.The Home Nurture Environment Questionnaire was used to assess the home environment of the infants and analyse its impact on the developmental quotient(evaluated by the Gesell Developmental Scale)and the rate of developmental delays at 18 months corrected age.Results A total of 41.454%of the infants were extremely preterm.The developmental quotient scores at 18 months corrected age were in the middle of the scale.The language domain had the highest rate of developmental delay(46.182%),followed by the adaptive domain(37.091%).Multiple logistic regression analyses showed that compared with infants in supportive home environments,infants with moderate/unsupportive home environments had significantly elevated risks of development delay:2.162-fold for global(odds ratio(OR)2.162,95% confidence interval(Cl)1.274 to 3.665,p=0.004),2.193-fold for fine motor(OR 2.193,95%CI 1.161 to 4.140,p=0.016),2.249-fold for language(0R 2.249,95%CI 1.336 to 3.786,p=0.002)and 2.042-fold for personal-social(OR 2.042,95%CI 1.149 to 3.628,p=0.015).Conclusions A supportive home environment is a crucial protective factor for the neuropsychological development of preterm infants.It is associated with higher developmental quotient scores and protects against neuropsychiatric delays.Incorporating evaluation and continuous improvement of the home environment into the management framework for preterm infants to promote optimal neurodevelopment is essential.
基金Chongqing Medical University Future Medical Youth Innovation Team Development Support Program,No.03030299QCW0007.
文摘BACKGROUND The effect of the number of lymph node dissections(LNDs)during radical resection for colorectal cancer(CRC)on overall survival(OS)remains controver-sial.AIM To investigate the association between the number of LNDs and OS in patients with tumor node metastasis(TNM)stage Ⅰ–Ⅱ CRC undergoing radical resection.METHODS Patients who underwent radical resection for CRC at a single-center hospital between January 2011 and December 2021 were retrospectively analyzed.Cox regression analyses were performed to identify the independent predictors of OS at different T stages.RESULTS A total of 2850 patients who underwent laparoscopic radical resection for CRC were enrolled.At stage T1,age[P<0.01,hazard ratio(HR)=1.075,95%confidence interval(CI):1.019-1.134]and tumour size(P=0.021,HR=3.635,95%CI:1.210-10.917)were independent risk factors for OS.At stage T2,age(P<0.01,HR=1.064,95%CI:1.032-1.098)and overall complications(P=0.012,HR=2.297,95%CI:1.200-4.397)were independent risk factors for OS.At stage T3,only age(P<0.01,HR=1.047,95%CI:1.027-1.066)was an independent risk factor for OS.At stage T4,age(P<0.01,HR=1.057,95%CI:1.039-1.075)and body mass index(P=0.034,HR=0.941,95%CI:0.890-0.995)were independent risk factors for OS.However,there was no association between LNDs and OS in stages Ⅰ and Ⅱ.CONCLUSION The number of LDNs did not affect the survival of patients with TNM stages Ⅰ and Ⅱ CRC.Therefore,insufficient LNDs should not be a cause for alarm during the surgery.
基金Supported by the National Science and Technology Planning Project(No.2012BAH38F00)the Engineering Research Project of Communication University of China(No.3132016XN1622)
文摘With the development of stereoscopic technology, more attention is attracted on the stereoscopic three-dimensional(S3 D) content and service, and researches on images and videos have emerged in large numbers. This paper focuses mainly on visual comfort affected by characteristics of disparity for multiple objects. To find the relationship between disparity distribution and visual comfort perception, several subject evaluation experiments are done. The study contains two spatial distribution types of disparity: 1) only one of the foreground objects has zero disparity; 2) one of the foreground objects has positive disparity, while the other one has negative disparity. The experimental results and relative regression analysis provide appropriate relationship between disparity distribution and visual comfort for both conditions, which is significant to meet the applicant field in S3 D content acquisition, display adjustment and quality evaluation.
文摘An analysis of the influencing factors and mechanism of tourist revisiting willingness by adopting the multiple regressionmodel based on the survey data obtained from 581 valid questionnaires concerning Kaiping Diaolou and Villages reveals that the maininfluencing factors of revisit intention are:tourist spot image,cognitive attitude,tourists'expectation and satisfaction.Of the fourmain factors,tourists'cognitive attitude is the direct influence factor,and the image of the sites and tourists'expectation indirectlyinfluence the revisit intention through tourists'satisfaction.This research result provides a new approach to the market developmentfor the heritage villages.
文摘Objective To evaluate the factors affecting the incidence of intrahepatic venovenous shunt(IVVS)in patients with cirrhosis and its impact on hepatic venous pressure gradient(HVPG).Methods A retrospective analysis was performed on the data of patients with liver cirrhosis who received HVPG measurement in Nanjing Drum Tower Hospital from April 2013 to March 2022.Univariate and multivariate regression analyses were used to investigate the incidence rate and risk factors of IVVS and its impact on HVPG.The t-test and rank-sum test were used for the measurement data,and the x?test was used for the count data.Results A total of 242 cases with cirrhosis were included in the statistical analysis,including 54(22.3%)with IVVS and 188(77.7%)without IVVS.There was a statistically significant difference(P<0.05)in prothrombin time(PT),HVPG,and splenectomy history between the two groups of patients'baseline data(all P<0.05).The multiple logistic regression analysis results showed that PT was an independent risk factor for the occurrence of IVVS(P<0.05),and patients combined with IVVS had lower HVPG values[(17.58±5.57)mmHg vs.(11.92±5.38)mmHg,1 mmHg=0.133 kPa;t=6.623,P<0.001].Conclusion Patients with liver cirrhosis have a high incidence rate of IVVS,which is closely associated with a low prothrombin time.Additionally,patients combined with IVVS have low HVPG values,which affect its accuracy.
基金This study was supported by the Beijing Natural Science Foundation
文摘Background： Animal models of asphyxiation cardiac arrest （ACA） are frequently used in basic research to mirror the clinical course of cardiac arrest （CA）. The rates of the return of spontaneous circulation （ROSC） inACA animal models are lower than those from studies that have utilized ventricular fibrillation （VF） animal models. The purpose of this study was to characterize the factors associated with the ROSC in the ACA porcine model. Methods： Forty-eight healthy miniature pigs underwent endotracheal tube clamping to induce CA. Once induced, CA was maintained untreated for a period of 8 min. Two minutes following the initiation of cardiopulmonary resuscitation （CPR）, defibrillation was attempted until ROSC was achieved or the animal died. To assess the factors associated with ROSC in this CA model, logistic regression analyses were performed to analyze gender, the time of preparation, the amplitude spectrum area （AMSA） from the beginning of CPR and the pH at the beginning of CPR. A receiver-operating characteristic （ROC） curve was used to evaluate the predictive value ofAMSA for ROSC. Results： ROSC was only 52.1% successful in this ACA porcine model. The multivariate logistic regression analyses revealed that ROSC significantly depended on the time of preparation, AMSA at the beginning of CPR and pH at the beginning of CPR. The area under the ROC curve in for AMSA at the beginning of CPR was 0.878 successful in predicting ROSC （95% confidence intervals： 0.773-0.983）, and the optimum cut-offvalue was 15.62 （specificity 95.7% and sensitivity 80.0%）. Conclusions： The time of preparation, AMSA and the pH at the beginning of CPR were associated with ROSC in this ACA porcine model. AMSA also predicted the likelihood of ROSC in this ACA animal model.
