Objective: To realize the effect and clinical value of implementing oral metronidazole + miconazole nitrate in patients with recurrent vaginosis. Methods: This study was analyzed retrospectively, and the time period w...Objective: To realize the effect and clinical value of implementing oral metronidazole + miconazole nitrate in patients with recurrent vaginosis. Methods: This study was analyzed retrospectively, and the time period was controlled from April 2020 to August 2021.200 consecutive patients with recurrent candida vaginitis in our hospital were admitted and randomized, and 100 consecutive patients were included in each group. The control group was given metronidazole treatment, and the observation group used miconazole nitrate based on the control group. The disease recurrence rate, incidence of adverse reactions, time to clinical symptom improvement, clinical efficacy, Candida clearance rate, and vaginal health status were observed and compared. Results: The clinical efficacy of the observed group was 97.00%, the incidence of adverse reactions was only 3.00%, 88.00% and 11.00% of the control groups, respectively, and P 0.05. In the observation group treated with combination therapy, the patients had a short improvement time of clinical symptoms, a good vaginal health status, and a high vaginal cleanliness, with P 0.05. Patients in the post-treatment observation group had higher Candida clearance and lower disease recurrence rate, and the data were P 0.05 compared to the control group. Conclusion: Oral metronidazole plus miconazole nitrate in treating recurrent candida vaginitis can shorten the clinical symptoms, improve the vaginal health and improve the clinical effect.展开更多
文摘Objective: To realize the effect and clinical value of implementing oral metronidazole + miconazole nitrate in patients with recurrent vaginosis. Methods: This study was analyzed retrospectively, and the time period was controlled from April 2020 to August 2021.200 consecutive patients with recurrent candida vaginitis in our hospital were admitted and randomized, and 100 consecutive patients were included in each group. The control group was given metronidazole treatment, and the observation group used miconazole nitrate based on the control group. The disease recurrence rate, incidence of adverse reactions, time to clinical symptom improvement, clinical efficacy, Candida clearance rate, and vaginal health status were observed and compared. Results: The clinical efficacy of the observed group was 97.00%, the incidence of adverse reactions was only 3.00%, 88.00% and 11.00% of the control groups, respectively, and P 0.05. In the observation group treated with combination therapy, the patients had a short improvement time of clinical symptoms, a good vaginal health status, and a high vaginal cleanliness, with P 0.05. Patients in the post-treatment observation group had higher Candida clearance and lower disease recurrence rate, and the data were P 0.05 compared to the control group. Conclusion: Oral metronidazole plus miconazole nitrate in treating recurrent candida vaginitis can shorten the clinical symptoms, improve the vaginal health and improve the clinical effect.
