Autologous bone marrow-derived mesenchymal stem cells(BMSCs)have been shown to promote osteogenesis;however,the effects of allogeneic BMSCs(allo-BMSCs)on bone regeneration remain unclear.Therefore,we explored the bone...Autologous bone marrow-derived mesenchymal stem cells(BMSCs)have been shown to promote osteogenesis;however,the effects of allogeneic BMSCs(allo-BMSCs)on bone regeneration remain unclear.Therefore,we explored the bone regeneration promotion effect of allo-BMSCs in 3D-printed autologous bone particle(ABP)scaffolds.First,we concurrently printed scaffolds with polycaprolactone,ABPs,and allo-BMSCs for appropriate support,providing bioactive factors and seed cells to promote osteogenesis.In vitro studies showed that ABP scaffolds promoted allo-BMSC osteogenic differentiation.In vivo studies revealed that the implantation of scaffolds loaded with ABPs and allo-BMSCs into canine skull defects for nine months promoted osteogenesis.Further experiments suggested that only a small portion of implanted allo-BMSCs survived and differentiated into vascular endothelial cells,chondrocytes,and osteocytes.The implanted allo-BMSCs released stromal cell-derived factor 1 through paracrine signaling to recruit native BMSCs into the defect,promoting bone regeneration.This study contributes to our understanding of allo-BMSCs,providing information relevant to their future application.展开更多
BACKGROUND Lung ultrasonography is being increasingly used in mechanically ventilated patients to evaluate the lung aeration during incremental positive end expiratory pressure(PEEP)adjustments and to evaluate the wea...BACKGROUND Lung ultrasonography is being increasingly used in mechanically ventilated patients to evaluate the lung aeration during incremental positive end expiratory pressure(PEEP)adjustments and to evaluate the weaning process from mechanical ventilation.The effects of PEEP may vary across different lung pathologies and may not consistently correlate with changes in lung aeration as assessed by lung ultrasound scores(LUSs).AIM To assess the role of lung ultrasonography in evaluating lung aeration during the application of PEEP in mechanically ventilated patients with various lung pathologies.METHODS An observational study was conducted over 18 months in a tertiary care hospital.Patients of both genders,aged between 18-75 years,who had been admitted to the intensive care unit,and required mechanical ventilation,were studied.A standard ventilatory strategy was used and incremental levels of PEEP[5,10,and 15 cm water(H_(2)O)]were applied.Baseline characteristics,including oxygen saturation(SpO2),LUS,mean arterial pressure(MAP),heart rate(HR),and their changes with incremental PEEP levels,were recorded and analyzed.RESULTS In this study,45.9%of patients required a PEEP of 5 cm H_(2)O to achieve the endpoint of lung aeration(LUS of 0).In addition,86.5% and 13.5% of patients reached the endpoint of lung aeration at PEEP levels of 10 and 15 cm H_(2)O,respectively.The proportion of patients with higher lung scores decreased significantly with increasing PEEP levels(P<0.001 for 5 and 10 cm H_(2)O and P=0.032 for 15 cm H_(2)O).SpO2 increased significantly with higher PEEP levels(P<0.001),confirming the effectiveness of PEEP in improving oxygenation.The results also revealed a significant increase in HR and a decrease in MAP following the application of higher PEEP levels.CONCLUSION Increasing PEEP levels in mechanically ventilated patients improves lung aeration,which can be effectively assessed using bedside lung ultrasonography.展开更多
Employee selection is a critical process that directly impacts organizational performance,productivity,and strategic success.This comprehensive article explores the multifaceted landscape of contemporary employee sele...Employee selection is a critical process that directly impacts organizational performance,productivity,and strategic success.This comprehensive article explores the multifaceted landscape of contemporary employee selection tools,examining their theoretical foundations,practical applications,psychological underpinnings,and empirical effectiveness.By systematically analyzing various selection methodologies,this research provides insights into the complex decision-making processes that organizations employ to identify,evaluate,and recruit top talent.The article critically evaluates the reliability,validity,advantages,and limitations of each selection tool,offering a nuanced perspective on their implementation and potential organizational impact.展开更多
1.Qiushi Chair Professor Applicants should be scholars with systematic and innovative achievements and extensive academic recognition by international peers,such as recipients of internationally renowned awards,academ...1.Qiushi Chair Professor Applicants should be scholars with systematic and innovative achievements and extensive academic recognition by international peers,such as recipients of internationally renowned awards,academicians of the Academy of Sciences or the Academy of Engineering of developed countries,and other international top scholars.展开更多
This paper presents an innovative design of a Bionic Powered Ankle Prosthesis(BPAP)utilizing a muscle recruitment mechanism-inspired clutch,aimed at achieving biomimetic simulation of ankle muscle function.To address ...This paper presents an innovative design of a Bionic Powered Ankle Prosthesis(BPAP)utilizing a muscle recruitment mechanism-inspired clutch,aimed at achieving biomimetic simulation of ankle muscle function.To address the varying stiffness requirements of the prosthesis across different gaits,the clutch dynamically switch between different rope bundle combinations.The mechanical characteristics during the load traction process of the selected flexible ropes are also studied.A mathematical model of the series elastic drive system is established.The optimization is carried out with the minimum peak power required by the motor as the optimization goal.The experimental results show that by applying a clutch with human muscle recruitment mechanism,the proposed prosthesis can achieve better energy efficiency at different speeds.展开更多
With the rapid development of technology,the application of artificial intelligence in the field of education is becoming increasingly widespread.As a core course of the human resource management major,“Personnel Rec...With the rapid development of technology,the application of artificial intelligence in the field of education is becoming increasingly widespread.As a core course of the human resource management major,“Personnel Recruitment and Evaluation”has a strong practical characteristic,making case teaching a key link.In this context,the importance of artificial intelligence to the case teaching of this course has become more prominent.This paper uses the literature research method and case analysis method to deeply explore the effective mode of artificial intelligence,enabling the case teaching of“Personnel Recruitment and Evaluation.”The research finds that artificial intelligence plays an important role in case screening and updating,in-depth analysis,and the construction of virtual simulation scenarios.However,its application also faces problems such as high technical costs,insufficient technical abilities of teachers,and data security and privacy.In response to these challenges,this paper proposes countermeasures such as reasonable planning of technology investment,strengthening teacher training,and improving the data security management mechanism.展开更多
This study evaluates the effectiveness of high-caliber talent recruitment at Jiangsu H Vocational College,a private vocational institution in China,amidst the evolving landscape of higher education.As vocational colle...This study evaluates the effectiveness of high-caliber talent recruitment at Jiangsu H Vocational College,a private vocational institution in China,amidst the evolving landscape of higher education.As vocational colleges increasingly prioritize quality and competitiveness,recruiting high-caliber talent is critical for enhancing academic capacity and supporting local socio-economic development.Employing a mixed-methods approach,including questionnaires,statistical analysis(using SPSS),the Analytic Hierarchy Process(AHP),and semi-structured interviews,the study constructs an evaluation framework to assess recruitment outcomes.Findings reveal challenges such as a uniform talent structure,limited research capacity,outdated evaluation methods,and inadequate recruitment mechanisms.Key issues include misaligned recruitment perspectives,unscientific planning,and insufficient promotional and supportive environments.To address these,the study proposes dynamic recruitment and management systems,strategic recruitment plans aligned with institutional goals,robust performance evaluations,and incentives to foster talent motivation and broader faculty development.These strategies aim to strengthen Jiangsu H’s talent ecosystem,enhance teaching and research capabilities,and ensure sustainable institutional growth,offering insights for other vocational colleges.展开更多
This study developed a recruitment forecasting model based on a new concept of the stock recruitment relationship. No density-dependent effect in the relationship was assumed in the model, which showed that fluctuatio...This study developed a recruitment forecasting model based on a new concept of the stock recruitment relationship. No density-dependent effect in the relationship was assumed in the model, which showed that fluctuations in recruitment and spawning stock biomass of Japanese sardine in the northwestern Pacific can be explained mainly by environmental factors and the effects of fishing. The February Arctic Oscillation (AO) and sea surface temperature over the southern area of the Kuroshio Extension (30 - 35°N and 145 - 180°E;KEST) were used as the environmental factors. The recruitment forecasting model is proposed: The values for recruitment (), spawning stock biomass, (), in year t, forecast by this model accurately reproduced those estimated by tuning virtual population analysis (VPA), and the pattern of variability in the stock recruitment relationship was also reproduced well. In conclusion, a density-dependent effect does not necessarily have to be included to explain the large variations in recruitment and the spawning stock biomass of the Japanese sardine.展开更多
Many estuarine and coastal planktonic copepods depend on the hatching of benthic resting eggs for recruitment ofnauplii to the water column population. The potential effects of two organochlorine pesticides, hexchlori...Many estuarine and coastal planktonic copepods depend on the hatching of benthic resting eggs for recruitment ofnauplii to the water column population. The potential effects of two organochlorine pesticides, hexchloriobinzene (HCH) and dichlorodiphenyltrichloroethane (DDT), on the recruitment of A ccu'tla pacifica nauplii from benthic resting eggs in the seabed of Xiamen Bay were experimentally investigated. The abundance of A. pacifica nauplii hatched from the sediment significantly decreased with the increase of pesticide concentration. Trimmed Spearman-Karber analysis gave sediment 96-h LC50 values were 84.81 ng/g for HCH, and 157.94 ng/g for DDT. The median AI (Al50) was -0.77, which suggested that the combined effect of riCH and DDT showed a weak effect than individual effects. There was a positive relationship between mortality and exposure time in DDT treatment, while the relationship was not significant in HCH treatment. The results suggest that organochlorine pesticides can reduce recruitment of A. pacifica nauplii from benthic resting eggs to planktonic population.展开更多
Many estuarine and coastal planktonic copepods depend on the hatching of benthic resting eggs for recruitment of nauplii to the water column population. The distribution and abundance of viable resting eggs of Acartia...Many estuarine and coastal planktonic copepods depend on the hatching of benthic resting eggs for recruitment of nauplii to the water column population. The distribution and abundance of viable resting eggs of Acartia pacifica in the Xiamen Bay were determined by the presence of nauplii in the laboratory. The number of viable eggs var/ed temporally and spatially. The maximum number (9.2×10^4m^-2) of viable eggs was in summer. In spring the average abundance of viable eggs was 5.6×10^4 m^-2. The abundances of viable eggs in fall and winter were similar, respectively 2.7×10^4 and 3.3×10^4m^-2, which were the lowest in the year. The numbers of viable eggs inside the stations of the Xiamen Bay were higher than those outside the stations. The viable eggs were found at all depths (0-10 cm),although not in every station. The maximum number did not necessarily occur in the uppermost centimeter of the sediments but often occurred several centimeters below the water-sediment interface. The accumulation of viable eggs in the seabed of a subtropical bay constitutes a potential source of recruitment of nauplii into the pelagic population.展开更多
BACKGROUND:Animal experiments showed that recruitment maneuver (RM) and protective ventilation strategy of the lung could improve oxygenation and reduce extravascular lung water. This study was to investigate the e...BACKGROUND:Animal experiments showed that recruitment maneuver (RM) and protective ventilation strategy of the lung could improve oxygenation and reduce extravascular lung water. This study was to investigate the effects of RM on respiratory mechanics and extravascular lung water index (EVLWI) in patients with acute respiratory distress syndrome (ARDS). METHODS:Thirty patients with ARDS were randomized into a RM group and a non-RM group. In the RM group, after basic mechanical ventilation stabilized for 30 minutes, RM was performed and repeated once every 12 hours for 3 days. In the non-RM group, lung protective strategy was conducted without RM. Oxygenation index (PaO2/FiO2), peak inspiratory pressure (PIP), Plateau pressure (Pplat), static pulmonary compliance (Cst) and EVLWI of patients before treatment and at 12, 24, 48, 72 hours after the treatment were measured and compared between the groups. Hemodynamic changes were observed before and after RM. One-way ANOVA, Student's t test and Fisher's exact test were used to process the data. RESULTS:The levels of PaO2/FiO2 and Cst increased after treatment in the two groups, but they were higher in the RM group than in the non-RM group (P〈0.05). The PIP and Pplat decreased after treatment in the two groups, but they were lower in the RM group than in the non-RM group (P〈0.05). The EVLWI in the two groups showed downward trend after treatment (P〈0.05), and the differences were signifcant at all time points (P〈0.01); the EVLWI in the RM group was lower than that in the non-RM group at 12, 24, 48 and 72 hours (P〈0.05 or P〈0.01). Compared with pre-RM, hemodynamics changes during RM were significantly different (P〈0.01); compared with pre-RM, the changes were not significantly different at 120 seconds after the end of RM (P〉0.05). CONCLUSIONS: RM could reduce EVLWI, increase oxygenation and lung compliance. The effect of RM on hemodynamics was transient.展开更多
Acute respiratory distress syndrome(ARDS) represents a serious problem in critically ill patients and is associated with in-hospital mortality rates of 33%-52%. Recruitment maneuvers(RMs) are a simple, low-cost, feasi...Acute respiratory distress syndrome(ARDS) represents a serious problem in critically ill patients and is associated with in-hospital mortality rates of 33%-52%. Recruitment maneuvers(RMs) are a simple, low-cost, feasible intervention that can be performed at the bedside in patients with ARDS. RMs are characterized by the application of airway pressure to increase transpulmonary pressure transiently. Once non-aerated lung units are reopened, improvements are observed in respiratory system mechanics, alveolar reaeration on computed tomography, and improvements in gas exchange(functional recruitment). However, the reopening process could lead to vascular compression, which can be associated with overinflation, and gas exchange may not improve as expected(anatomical recruitment). The purpose of this review was to discuss the effects of different RM strategies- sustained inflation, intermittent sighs, and stepwise increases of positive end-expiratory pressure(PEEP) and/or airway inspiratory pressure- on the following parameters: hemodynamics, oxygenation, barotrauma episodes, and lung recruitability through physiological variables and imaging techniques. RMs and PEEP titration are interdependent events for the success of ventilatory management. PEEP should be adjusted on the basis of respiratory system mechanics and oxygenation. Recent systematic reviews and meta-analyses suggest that RMs are associated with lower mortality in patients with ARDS. However, the optimal RM method(i.e., that providing the best balance of benefit and harm) and the effects of RMs on clinical outcome are still under discussion, and further evidence is needed.展开更多
Floodplains are important and distinctive ecosystems around the world,and the recruitment of ichthyoplankton from river to floodplain lakes is crucial to maintain this unique ecosystem.However,this process has not bee...Floodplains are important and distinctive ecosystems around the world,and the recruitment of ichthyoplankton from river to floodplain lakes is crucial to maintain this unique ecosystem.However,this process has not been well documented.In this study,ichthyoplankton were sampled to investigate the details of ichthyoplankton recruitment from the Changjiang(Yangtze)River to the Dongting Lake via a floodway channel,the Songzi River,from May to July in 2013 and 2014.During the study period,41 species of eggs and larvae were sampled.Among the samples,16 were river-lake migratory species(RL),representing 23.5%of the species in the Dongting Lake.In 2013,an estimated 130 million eggs and 3180 million larvae drifted through the sampling section,and in 2014,an estimated 1 060 million eggs and 1040 million larvae drifted through the sampling section.The amount of eggs and larvae of RL reached 3 210 million in 2013 and 1 850 million in 2014,respectively.These results demonstrated the importance of ichthyoplankton recruitment from the river to the lake,as species diversity will decrease sharply without this recruitment.Canonical correspondence analysis(CCA)showed that water temperature and water flow are the two most important factors influencing the spawning activities of fish.To maintain the high fish diversity in the Changjiang floodplain,we suggest to irrigate the channel to increase water discharge and increase the transport of ichthyoplankton from the Changjiang mainstream into the Dongting Lake.展开更多
This article explored China’s urban employment dynamics with particular focus on the city size effect.Big data derived from the largest recruitment website were used to examine the direct and indirect impacts of city...This article explored China’s urban employment dynamics with particular focus on the city size effect.Big data derived from the largest recruitment website were used to examine the direct and indirect impacts of city size on employment demand by using mediating and moderating models.We also investigated the roles of the government and location factors which have seldom been considered in literature.Results showed that the concentration degree of new jobs is higher than that of stock employment and population across cities,implying a path dependency mechanism of job creation and employment expansion.Meanwhile,numerous job posts in inland central cities are probably a symptom of more even distribution of employment in future China.Econometric models further verified the significant correlation between city size and job creation.Moreover,industrial diversity,fixed asset investment,and spatial location have heterogeneous effects on employment demand in cities of different sizes and different levels of administration.These results can not only deepen our understanding of the crucial role of city size in urban employment growth but also demonstrate the future trend of labor and population geography of China.Policy implications are then proposed for job creation in cities of China and other developing countries.展开更多
Alpine treeline ecotones are harsh environment for tree establishment due to low temperature.Tree establishment at treelines requires favorable climate,suitable microsites,and viable seeds.But most researches have bee...Alpine treeline ecotones are harsh environment for tree establishment due to low temperature.Tree establishment at treelines requires favorable climate,suitable microsites,and viable seeds.But most researches have been addressed treeline microclimate and its effects on tree regeneration,the knowledge of seed quantity and quality and its controls on seedling recruitment were limited.We measured seed rain,soil seed bank,seed germination rate and seedling recruitment in natural forests in combination with seed transplanting manipulation to evaluate the controls of seed quantity and quality on seedling recruitment of Abies georgei var.smithii(smith fir)along altitudinal gradient,with focus on treeline ecotone in the Sygera Mountains,southeastern Tibetan Plateau.Both seed quantity and seed quality of smith fir decreased with increasing altitude and was thereby associated with decline in seed germination rate.Seed quantity and seedling recruitment were better in north-facing slope than in south slope.The treeline ecotone above 42oo m appeared as the threshold altitude to sharply decrease seed quality and seedling recruitment.The emergence and overwintering rates of transplanting seeds from 3600-38oo m also went down remarkably above 4200 m at north-facing slope.It also underpins the fact that treeline ecotone is the bottleneck of seedling recruitment.Our results suggest that seed quantity and quality are the principal limitation of treeline upward advance.This study also provides evidence to support stable treeline position in southeastern Tibetan Plateau.展开更多
Objective:To evaluate the efficacy and safety of protective lung ventilation strategy combined with lung recruitment maneuver (RM) in the treatment patients with acute respiratory distress syndrome (ARDS).Methods:Tota...Objective:To evaluate the efficacy and safety of protective lung ventilation strategy combined with lung recruitment maneuver (RM) in the treatment patients with acute respiratory distress syndrome (ARDS).Methods:Totally 74 patients with ARDS admitted to the Department of Intensive Care Unit, Changshu Second People's Hospital in Jiangsu Province between September 2010 and June 2013 were selected and randomly divided into lung recruitment group and non-lung recruitment group, and the initial ventilation solution for both groups was synchronized intermittent mandatory ventilation (SIMV). For RM, SIMV mode (pressure control and pressure support) was adopted. Positive end expiratory pressure (PEEP) was increased by 5 cm H2O every time and maintained for 40-50 s before entering the next increasing period, and the peak airway pressure was kept below 45 cm H2O. After PEEP reached the maximum value, it was gradually reduced by 5 cm H2O every time and finally maintained at 15 cm H2O for 10 min.Results:A total of 74 patients with mean age of (49.0±18.6) years old were enrolled, 36 patients were enrolled in lung recruitment maneuver (RM) group and 38 patients were enrolled into non-lung recruitment maneuver (non-RM) group. 44 were male and accounted for 59.5% of all the patients. For the indicators such as PEEP, pressure support (PS), plateau airway pressure (Pplat), peak airway pressure (Ppeak), vital capacity (VC) and fraction of inspired oxygen (FiO2), no statistical differences in the indicators were found between the RM group and non-RM group on D1, D3 and D7 (P>0.05), except that only FiO2 of RM group on D7 was significantly lower than that of non-RM group (47.2±10.0) vs. (52.2±10.5),P<0.05]. For the indicators of blood gas analysis, including pH, arterial oxygen pressure (PaO2), arterial carbon dioxide pressure (PaCO2) and oxygenation index (PaO2/FiO2), PaO2 and PaO2/FiO2 of RM group were significantly higher than those of non-RM group on D7, and the values were [(90.2±16.1) mmHg vs. (76.4±11.3) mmHg,P<0.05] and [(196.5±40.7) mmHg vs. (151.7±37.3) mmHg,P<0.05] respectively. There was no statistical difference in heart rate (HR), cardiac index (CI), central venous pressure (CVP) or mean arterial pressure (MAP) between RM group and non-RM group on D1, D3 and D7 (P>0.05). 28-day mortality, ICU mortality and in-hospital mortality were 25% vs. 28.9%, 25% vs. 26.3% and 36.1% vs. 39.5% respectively between RM group and non-RM group (allP>0.05).Conclusion:Protective lung ventilation strategy combined with lung recruitment maneuver can improve the indicators such as PaO2, FiO2 and PaO2/FiO2 on D7, but failed to improve the final outcomes such as 28-day mortality, ICU mortality and in-hospital mortality.展开更多
Eremosparton songoricum,a rare and endemic sand dune plant,appears to be experiencing recruitment failure.The structure of five populations from the Gurbantunggut Desert,China,was investigated for recruitment patterns...Eremosparton songoricum,a rare and endemic sand dune plant,appears to be experiencing recruitment failure.The structure of five populations from the Gurbantunggut Desert,China,was investigated for recruitment patterns,and two of them were examined for flowering,pollination and seed germination limits on regeneration.The results showed that total 150 seedlings only occurred on line transects in riverside Dure population,but they all died half a month later;no seedlings occurred in other four hinterland desert populations indicating recruitment was a failure at all populations although flowers were plentiful.Reproductive success depends on pollinators.Nectar is 'reward' for pollinators,with 0.06 μL-0.12 μL and 0.15 μL-0.35 μL per flower in Dure and Kabu populations,respectively,in continuously two secreting days.Spontaneous self pollination is rare with nearly zero fruit production.Geitonogamous self pollination is predominant with 14.47% fruit set.Seed mass in the riverside Dure population was significantly greater than that in other hinterland desert populations.Consequently,the Dure population exhibited a significantly higher germination rate(about 90%) than those in other populations(about 30%).Results suggested that recruitment failure of E.songoricum is not due to flower shortage,pollination limitation,or poor seed germination but environmental pressure and/or human disturbance.展开更多
基金supported by the Science and Technology Development Fund of the Fourth Military Medical University(No.2016XB051)the Military Medical Promotion Plan of the Fourth Military Medical University(No.2016TSA-005)+2 种基金the Science and Technology Program of Guangzhou(No.201604040002)the Youth Development Project of Air Force Medical University(No.21QNPY072)the Xijing Hospital Booster Program(No.XJZT24CZ10).
文摘Autologous bone marrow-derived mesenchymal stem cells(BMSCs)have been shown to promote osteogenesis;however,the effects of allogeneic BMSCs(allo-BMSCs)on bone regeneration remain unclear.Therefore,we explored the bone regeneration promotion effect of allo-BMSCs in 3D-printed autologous bone particle(ABP)scaffolds.First,we concurrently printed scaffolds with polycaprolactone,ABPs,and allo-BMSCs for appropriate support,providing bioactive factors and seed cells to promote osteogenesis.In vitro studies showed that ABP scaffolds promoted allo-BMSC osteogenic differentiation.In vivo studies revealed that the implantation of scaffolds loaded with ABPs and allo-BMSCs into canine skull defects for nine months promoted osteogenesis.Further experiments suggested that only a small portion of implanted allo-BMSCs survived and differentiated into vascular endothelial cells,chondrocytes,and osteocytes.The implanted allo-BMSCs released stromal cell-derived factor 1 through paracrine signaling to recruit native BMSCs into the defect,promoting bone regeneration.This study contributes to our understanding of allo-BMSCs,providing information relevant to their future application.
文摘BACKGROUND Lung ultrasonography is being increasingly used in mechanically ventilated patients to evaluate the lung aeration during incremental positive end expiratory pressure(PEEP)adjustments and to evaluate the weaning process from mechanical ventilation.The effects of PEEP may vary across different lung pathologies and may not consistently correlate with changes in lung aeration as assessed by lung ultrasound scores(LUSs).AIM To assess the role of lung ultrasonography in evaluating lung aeration during the application of PEEP in mechanically ventilated patients with various lung pathologies.METHODS An observational study was conducted over 18 months in a tertiary care hospital.Patients of both genders,aged between 18-75 years,who had been admitted to the intensive care unit,and required mechanical ventilation,were studied.A standard ventilatory strategy was used and incremental levels of PEEP[5,10,and 15 cm water(H_(2)O)]were applied.Baseline characteristics,including oxygen saturation(SpO2),LUS,mean arterial pressure(MAP),heart rate(HR),and their changes with incremental PEEP levels,were recorded and analyzed.RESULTS In this study,45.9%of patients required a PEEP of 5 cm H_(2)O to achieve the endpoint of lung aeration(LUS of 0).In addition,86.5% and 13.5% of patients reached the endpoint of lung aeration at PEEP levels of 10 and 15 cm H_(2)O,respectively.The proportion of patients with higher lung scores decreased significantly with increasing PEEP levels(P<0.001 for 5 and 10 cm H_(2)O and P=0.032 for 15 cm H_(2)O).SpO2 increased significantly with higher PEEP levels(P<0.001),confirming the effectiveness of PEEP in improving oxygenation.The results also revealed a significant increase in HR and a decrease in MAP following the application of higher PEEP levels.CONCLUSION Increasing PEEP levels in mechanically ventilated patients improves lung aeration,which can be effectively assessed using bedside lung ultrasonography.
文摘Employee selection is a critical process that directly impacts organizational performance,productivity,and strategic success.This comprehensive article explores the multifaceted landscape of contemporary employee selection tools,examining their theoretical foundations,practical applications,psychological underpinnings,and empirical effectiveness.By systematically analyzing various selection methodologies,this research provides insights into the complex decision-making processes that organizations employ to identify,evaluate,and recruit top talent.The article critically evaluates the reliability,validity,advantages,and limitations of each selection tool,offering a nuanced perspective on their implementation and potential organizational impact.
文摘1.Qiushi Chair Professor Applicants should be scholars with systematic and innovative achievements and extensive academic recognition by international peers,such as recipients of internationally renowned awards,academicians of the Academy of Sciences or the Academy of Engineering of developed countries,and other international top scholars.
基金supported in part by National Natural Science Foundation of China[Grant No.62203356].
文摘This paper presents an innovative design of a Bionic Powered Ankle Prosthesis(BPAP)utilizing a muscle recruitment mechanism-inspired clutch,aimed at achieving biomimetic simulation of ankle muscle function.To address the varying stiffness requirements of the prosthesis across different gaits,the clutch dynamically switch between different rope bundle combinations.The mechanical characteristics during the load traction process of the selected flexible ropes are also studied.A mathematical model of the series elastic drive system is established.The optimization is carried out with the minimum peak power required by the motor as the optimization goal.The experimental results show that by applying a clutch with human muscle recruitment mechanism,the proposed prosthesis can achieve better energy efficiency at different speeds.
基金The 2024 Chinese Business Studies Research Project,"Special Topic on Corporate Cases'Uniting Hearts,Empowering Employees-The Cultural DNA of CP Group's 7-Eleven"(Project No.:secbr-zt-05)。
文摘With the rapid development of technology,the application of artificial intelligence in the field of education is becoming increasingly widespread.As a core course of the human resource management major,“Personnel Recruitment and Evaluation”has a strong practical characteristic,making case teaching a key link.In this context,the importance of artificial intelligence to the case teaching of this course has become more prominent.This paper uses the literature research method and case analysis method to deeply explore the effective mode of artificial intelligence,enabling the case teaching of“Personnel Recruitment and Evaluation.”The research finds that artificial intelligence plays an important role in case screening and updating,in-depth analysis,and the construction of virtual simulation scenarios.However,its application also faces problems such as high technical costs,insufficient technical abilities of teachers,and data security and privacy.In response to these challenges,this paper proposes countermeasures such as reasonable planning of technology investment,strengthening teacher training,and improving the data security management mechanism.
文摘This study evaluates the effectiveness of high-caliber talent recruitment at Jiangsu H Vocational College,a private vocational institution in China,amidst the evolving landscape of higher education.As vocational colleges increasingly prioritize quality and competitiveness,recruiting high-caliber talent is critical for enhancing academic capacity and supporting local socio-economic development.Employing a mixed-methods approach,including questionnaires,statistical analysis(using SPSS),the Analytic Hierarchy Process(AHP),and semi-structured interviews,the study constructs an evaluation framework to assess recruitment outcomes.Findings reveal challenges such as a uniform talent structure,limited research capacity,outdated evaluation methods,and inadequate recruitment mechanisms.Key issues include misaligned recruitment perspectives,unscientific planning,and insufficient promotional and supportive environments.To address these,the study proposes dynamic recruitment and management systems,strategic recruitment plans aligned with institutional goals,robust performance evaluations,and incentives to foster talent motivation and broader faculty development.These strategies aim to strengthen Jiangsu H’s talent ecosystem,enhance teaching and research capabilities,and ensure sustainable institutional growth,offering insights for other vocational colleges.
文摘This study developed a recruitment forecasting model based on a new concept of the stock recruitment relationship. No density-dependent effect in the relationship was assumed in the model, which showed that fluctuations in recruitment and spawning stock biomass of Japanese sardine in the northwestern Pacific can be explained mainly by environmental factors and the effects of fishing. The February Arctic Oscillation (AO) and sea surface temperature over the southern area of the Kuroshio Extension (30 - 35°N and 145 - 180°E;KEST) were used as the environmental factors. The recruitment forecasting model is proposed: The values for recruitment (), spawning stock biomass, (), in year t, forecast by this model accurately reproduced those estimated by tuning virtual population analysis (VPA), and the pattern of variability in the stock recruitment relationship was also reproduced well. In conclusion, a density-dependent effect does not necessarily have to be included to explain the large variations in recruitment and the spawning stock biomass of the Japanese sardine.
基金The National Natural Science Foundation of China (No. 40506002 40076034) PRIC Innovation Foundation of Polar Science forYoung Scientists (No. JDQ200502)
文摘Many estuarine and coastal planktonic copepods depend on the hatching of benthic resting eggs for recruitment ofnauplii to the water column population. The potential effects of two organochlorine pesticides, hexchloriobinzene (HCH) and dichlorodiphenyltrichloroethane (DDT), on the recruitment of A ccu'tla pacifica nauplii from benthic resting eggs in the seabed of Xiamen Bay were experimentally investigated. The abundance of A. pacifica nauplii hatched from the sediment significantly decreased with the increase of pesticide concentration. Trimmed Spearman-Karber analysis gave sediment 96-h LC50 values were 84.81 ng/g for HCH, and 157.94 ng/g for DDT. The median AI (Al50) was -0.77, which suggested that the combined effect of riCH and DDT showed a weak effect than individual effects. There was a positive relationship between mortality and exposure time in DDT treatment, while the relationship was not significant in HCH treatment. The results suggest that organochlorine pesticides can reduce recruitment of A. pacifica nauplii from benthic resting eggs to planktonic population.
文摘Many estuarine and coastal planktonic copepods depend on the hatching of benthic resting eggs for recruitment of nauplii to the water column population. The distribution and abundance of viable resting eggs of Acartia pacifica in the Xiamen Bay were determined by the presence of nauplii in the laboratory. The number of viable eggs var/ed temporally and spatially. The maximum number (9.2×10^4m^-2) of viable eggs was in summer. In spring the average abundance of viable eggs was 5.6×10^4 m^-2. The abundances of viable eggs in fall and winter were similar, respectively 2.7×10^4 and 3.3×10^4m^-2, which were the lowest in the year. The numbers of viable eggs inside the stations of the Xiamen Bay were higher than those outside the stations. The viable eggs were found at all depths (0-10 cm),although not in every station. The maximum number did not necessarily occur in the uppermost centimeter of the sediments but often occurred several centimeters below the water-sediment interface. The accumulation of viable eggs in the seabed of a subtropical bay constitutes a potential source of recruitment of nauplii into the pelagic population.
文摘BACKGROUND:Animal experiments showed that recruitment maneuver (RM) and protective ventilation strategy of the lung could improve oxygenation and reduce extravascular lung water. This study was to investigate the effects of RM on respiratory mechanics and extravascular lung water index (EVLWI) in patients with acute respiratory distress syndrome (ARDS). METHODS:Thirty patients with ARDS were randomized into a RM group and a non-RM group. In the RM group, after basic mechanical ventilation stabilized for 30 minutes, RM was performed and repeated once every 12 hours for 3 days. In the non-RM group, lung protective strategy was conducted without RM. Oxygenation index (PaO2/FiO2), peak inspiratory pressure (PIP), Plateau pressure (Pplat), static pulmonary compliance (Cst) and EVLWI of patients before treatment and at 12, 24, 48, 72 hours after the treatment were measured and compared between the groups. Hemodynamic changes were observed before and after RM. One-way ANOVA, Student's t test and Fisher's exact test were used to process the data. RESULTS:The levels of PaO2/FiO2 and Cst increased after treatment in the two groups, but they were higher in the RM group than in the non-RM group (P〈0.05). The PIP and Pplat decreased after treatment in the two groups, but they were lower in the RM group than in the non-RM group (P〈0.05). The EVLWI in the two groups showed downward trend after treatment (P〈0.05), and the differences were signifcant at all time points (P〈0.01); the EVLWI in the RM group was lower than that in the non-RM group at 12, 24, 48 and 72 hours (P〈0.05 or P〈0.01). Compared with pre-RM, hemodynamics changes during RM were significantly different (P〈0.01); compared with pre-RM, the changes were not significantly different at 120 seconds after the end of RM (P〉0.05). CONCLUSIONS: RM could reduce EVLWI, increase oxygenation and lung compliance. The effect of RM on hemodynamics was transient.
基金Supported by Brazilian Council for Scientific and Technological Development(CNPq),Carlos Chagas Filho Rio de Janeiro State Research Foundation(FAPERJ),Department of Science and Technology(DECIT)/Brazilian Ministry of HealthCoordination for the Improvement of Higher Level Personnel(CAPES)
文摘Acute respiratory distress syndrome(ARDS) represents a serious problem in critically ill patients and is associated with in-hospital mortality rates of 33%-52%. Recruitment maneuvers(RMs) are a simple, low-cost, feasible intervention that can be performed at the bedside in patients with ARDS. RMs are characterized by the application of airway pressure to increase transpulmonary pressure transiently. Once non-aerated lung units are reopened, improvements are observed in respiratory system mechanics, alveolar reaeration on computed tomography, and improvements in gas exchange(functional recruitment). However, the reopening process could lead to vascular compression, which can be associated with overinflation, and gas exchange may not improve as expected(anatomical recruitment). The purpose of this review was to discuss the effects of different RM strategies- sustained inflation, intermittent sighs, and stepwise increases of positive end-expiratory pressure(PEEP) and/or airway inspiratory pressure- on the following parameters: hemodynamics, oxygenation, barotrauma episodes, and lung recruitability through physiological variables and imaging techniques. RMs and PEEP titration are interdependent events for the success of ventilatory management. PEEP should be adjusted on the basis of respiratory system mechanics and oxygenation. Recent systematic reviews and meta-analyses suggest that RMs are associated with lower mortality in patients with ARDS. However, the optimal RM method(i.e., that providing the best balance of benefit and harm) and the effects of RMs on clinical outcome are still under discussion, and further evidence is needed.
基金Supported by the National Key Research and Development Program of China(No.2016YFC0402005)the Three Gorges Project EcoEnvironmental Monitoring System(No.JJ [2017]-011)+1 种基金the National Natural Science Foundation of China(No.NSFC31400359)the China Three Gorges Corporation(No.0704097)
文摘Floodplains are important and distinctive ecosystems around the world,and the recruitment of ichthyoplankton from river to floodplain lakes is crucial to maintain this unique ecosystem.However,this process has not been well documented.In this study,ichthyoplankton were sampled to investigate the details of ichthyoplankton recruitment from the Changjiang(Yangtze)River to the Dongting Lake via a floodway channel,the Songzi River,from May to July in 2013 and 2014.During the study period,41 species of eggs and larvae were sampled.Among the samples,16 were river-lake migratory species(RL),representing 23.5%of the species in the Dongting Lake.In 2013,an estimated 130 million eggs and 3180 million larvae drifted through the sampling section,and in 2014,an estimated 1 060 million eggs and 1040 million larvae drifted through the sampling section.The amount of eggs and larvae of RL reached 3 210 million in 2013 and 1 850 million in 2014,respectively.These results demonstrated the importance of ichthyoplankton recruitment from the river to the lake,as species diversity will decrease sharply without this recruitment.Canonical correspondence analysis(CCA)showed that water temperature and water flow are the two most important factors influencing the spawning activities of fish.To maintain the high fish diversity in the Changjiang floodplain,we suggest to irrigate the channel to increase water discharge and increase the transport of ichthyoplankton from the Changjiang mainstream into the Dongting Lake.
基金Major Project of National Social Sciences Foundation of China,No.20&ZD173。
文摘This article explored China’s urban employment dynamics with particular focus on the city size effect.Big data derived from the largest recruitment website were used to examine the direct and indirect impacts of city size on employment demand by using mediating and moderating models.We also investigated the roles of the government and location factors which have seldom been considered in literature.Results showed that the concentration degree of new jobs is higher than that of stock employment and population across cities,implying a path dependency mechanism of job creation and employment expansion.Meanwhile,numerous job posts in inland central cities are probably a symptom of more even distribution of employment in future China.Econometric models further verified the significant correlation between city size and job creation.Moreover,industrial diversity,fixed asset investment,and spatial location have heterogeneous effects on employment demand in cities of different sizes and different levels of administration.These results can not only deepen our understanding of the crucial role of city size in urban employment growth but also demonstrate the future trend of labor and population geography of China.Policy implications are then proposed for job creation in cities of China and other developing countries.
基金supported by the foundations of Special Research Program for Public-welfare Forestry(Grant No.200804001)Tibet Plateau Ecological Safety Barrier Monitor Evaluation Method and Technology Research(Grant No.KZCX2-XB3-08)Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA05090311)
文摘Alpine treeline ecotones are harsh environment for tree establishment due to low temperature.Tree establishment at treelines requires favorable climate,suitable microsites,and viable seeds.But most researches have been addressed treeline microclimate and its effects on tree regeneration,the knowledge of seed quantity and quality and its controls on seedling recruitment were limited.We measured seed rain,soil seed bank,seed germination rate and seedling recruitment in natural forests in combination with seed transplanting manipulation to evaluate the controls of seed quantity and quality on seedling recruitment of Abies georgei var.smithii(smith fir)along altitudinal gradient,with focus on treeline ecotone in the Sygera Mountains,southeastern Tibetan Plateau.Both seed quantity and seed quality of smith fir decreased with increasing altitude and was thereby associated with decline in seed germination rate.Seed quantity and seedling recruitment were better in north-facing slope than in south slope.The treeline ecotone above 42oo m appeared as the threshold altitude to sharply decrease seed quality and seedling recruitment.The emergence and overwintering rates of transplanting seeds from 3600-38oo m also went down remarkably above 4200 m at north-facing slope.It also underpins the fact that treeline ecotone is the bottleneck of seedling recruitment.Our results suggest that seed quantity and quality are the principal limitation of treeline upward advance.This study also provides evidence to support stable treeline position in southeastern Tibetan Plateau.
文摘Objective:To evaluate the efficacy and safety of protective lung ventilation strategy combined with lung recruitment maneuver (RM) in the treatment patients with acute respiratory distress syndrome (ARDS).Methods:Totally 74 patients with ARDS admitted to the Department of Intensive Care Unit, Changshu Second People's Hospital in Jiangsu Province between September 2010 and June 2013 were selected and randomly divided into lung recruitment group and non-lung recruitment group, and the initial ventilation solution for both groups was synchronized intermittent mandatory ventilation (SIMV). For RM, SIMV mode (pressure control and pressure support) was adopted. Positive end expiratory pressure (PEEP) was increased by 5 cm H2O every time and maintained for 40-50 s before entering the next increasing period, and the peak airway pressure was kept below 45 cm H2O. After PEEP reached the maximum value, it was gradually reduced by 5 cm H2O every time and finally maintained at 15 cm H2O for 10 min.Results:A total of 74 patients with mean age of (49.0±18.6) years old were enrolled, 36 patients were enrolled in lung recruitment maneuver (RM) group and 38 patients were enrolled into non-lung recruitment maneuver (non-RM) group. 44 were male and accounted for 59.5% of all the patients. For the indicators such as PEEP, pressure support (PS), plateau airway pressure (Pplat), peak airway pressure (Ppeak), vital capacity (VC) and fraction of inspired oxygen (FiO2), no statistical differences in the indicators were found between the RM group and non-RM group on D1, D3 and D7 (P>0.05), except that only FiO2 of RM group on D7 was significantly lower than that of non-RM group (47.2±10.0) vs. (52.2±10.5),P<0.05]. For the indicators of blood gas analysis, including pH, arterial oxygen pressure (PaO2), arterial carbon dioxide pressure (PaCO2) and oxygenation index (PaO2/FiO2), PaO2 and PaO2/FiO2 of RM group were significantly higher than those of non-RM group on D7, and the values were [(90.2±16.1) mmHg vs. (76.4±11.3) mmHg,P<0.05] and [(196.5±40.7) mmHg vs. (151.7±37.3) mmHg,P<0.05] respectively. There was no statistical difference in heart rate (HR), cardiac index (CI), central venous pressure (CVP) or mean arterial pressure (MAP) between RM group and non-RM group on D1, D3 and D7 (P>0.05). 28-day mortality, ICU mortality and in-hospital mortality were 25% vs. 28.9%, 25% vs. 26.3% and 36.1% vs. 39.5% respectively between RM group and non-RM group (allP>0.05).Conclusion:Protective lung ventilation strategy combined with lung recruitment maneuver can improve the indicators such as PaO2, FiO2 and PaO2/FiO2 on D7, but failed to improve the final outcomes such as 28-day mortality, ICU mortality and in-hospital mortality.
基金provided by the National Natural Science Foundation of China (31070472,30970547)the Key Knowledge Innovation Project of the Chinese Academy of Sciences (KSCX2-YW-Z-1020)
文摘Eremosparton songoricum,a rare and endemic sand dune plant,appears to be experiencing recruitment failure.The structure of five populations from the Gurbantunggut Desert,China,was investigated for recruitment patterns,and two of them were examined for flowering,pollination and seed germination limits on regeneration.The results showed that total 150 seedlings only occurred on line transects in riverside Dure population,but they all died half a month later;no seedlings occurred in other four hinterland desert populations indicating recruitment was a failure at all populations although flowers were plentiful.Reproductive success depends on pollinators.Nectar is 'reward' for pollinators,with 0.06 μL-0.12 μL and 0.15 μL-0.35 μL per flower in Dure and Kabu populations,respectively,in continuously two secreting days.Spontaneous self pollination is rare with nearly zero fruit production.Geitonogamous self pollination is predominant with 14.47% fruit set.Seed mass in the riverside Dure population was significantly greater than that in other hinterland desert populations.Consequently,the Dure population exhibited a significantly higher germination rate(about 90%) than those in other populations(about 30%).Results suggested that recruitment failure of E.songoricum is not due to flower shortage,pollination limitation,or poor seed germination but environmental pressure and/or human disturbance.