Savannah,Ga.,April 22,2025-Gulfstream Aerospace Corp.today announced its fleet has achieved an industry-leading 700 city-pair speed records with a Gulfstream G700 flight from Taipei to Miami.This flight commemorates t...Savannah,Ga.,April 22,2025-Gulfstream Aerospace Corp.today announced its fleet has achieved an industry-leading 700 city-pair speed records with a Gulfstream G700 flight from Taipei to Miami.This flight commemorates the 50-year anniversary of Gulfstream's first U.S.National Aeronautic Association(NAA)accredited speed record,set in 1975 by the Gulfstream GII.展开更多
Anthropogenic climate change is altering species distributions globally.While species distributions are expected to shift to higher latitudes and elevations under global warming,empirical evidence on distribution shif...Anthropogenic climate change is altering species distributions globally.While species distributions are expected to shift to higher latitudes and elevations under global warming,empirical evidence on distribution shifts is mixed,and factors mediating the direction and magnitude of range shifts remain unclear.Using a dataset of 132new provincial records for 96 resident bird species from 2000 to 2023,we measured geographic distance,latitudinal shift,and temperature shift from each new record to the historical range for each species to test for poleward shifts.We assessed taxonomic variation in the magnitude of range shifts and used phylogenetic generalized linear mixed models to quantify relationships between species traits and the extent of range shifts.Our results revealed that new records occurred at a mean geographic distance of 420 km from historical ranges,with mean latitudinal shifts of+1.68°(poleward)and temperature shifts of-1.33℃(toward colder climates).The magnitude of geographic range shifts was strongly constrained by phylogenetic relatedness.Habitat breadth,habitat openness,and centroid latitude of historical ranges emerged as significant predictors of range shifts.Our results suggest that resident bird species'geographic ranges in China are shifting poleward,but the magnitude of these shifts is non-random across lineages.Species with broader habitat preferences and those from warmer climates are more likely to shift farther from their historical ranges and toward higher latitudes.This study emphasizes taxonomic variation in species range shifts and highlights the need for species-and site-specific conservation strategies under global warming.展开更多
BACKGROUND The neurological and psychiatric sequelae of coronavirus disease 2019(COVID-19)have been documented,yet further data are needed to thoroughly evaluate the impact of COVID-19 on brain health years after the ...BACKGROUND The neurological and psychiatric sequelae of coronavirus disease 2019(COVID-19)have been documented,yet further data are needed to thoroughly evaluate the impact of COVID-19 on brain health years after the infection.AIM To examine whether COVID-19 infection is associated with exacerbation,recurrence,or progression of pre-existing neurological or psychiatric disorders-a highrisk population that is underrepresented in COVID-19 outcome research in National Guard Health Affair patients in 4-years following a COVID-19 diagnosis.METHODS For this multicenter retrospective cohort study,we used data from the National Guard hospitals electronic health records network(BestCare)with over 10 million patients.Our cohort comprised patients who had a COVID-19 diagnosis;a matched control cohort included patient did not expose to COVID-19 in same period.Age and sex were matching factors.We estimated the incidence of 14 neurological and psychiatric outcomes in nearly 4 years after a confirmed diagnosis of COVID-19.Using a multiple logistic regression,we compared incidences with those in propensity score-matched cohorts of patients with no exposure to COVID-19.Ramadan M et al.Neurological and psychiatric risks post-COVID-19 RESULTS Our primary cohort comprised 4437 patients diagnosed with COVID-19,and our propensity-score 1:1 matched control cohort comprised 4437 individuals.Nearly two-third of the COVID-19 cohort(71%)were diagnosed in 2020,and 2021.The most prevalent diagnoses for both cohorts were epilepsy 30.68%,mood disorder 23.92%,and nerve plexus disorder 22.13%.Dementia was nearly 4 times higher among COVID-19 cohort(8.27%)compared to the control cohort(2.57%).Five neurological and psychiatric outcomes had odds ratios(OR)that were significantly higher than 1 for people who had COVID-19 compared to people who had never been infected.These outcomes were cognitive deficit OR=1.54,95%confidence interval(CI):1.23-1.91,P=0.0001;nerve plexus disorder OR=1.13,95%CI:1.01-1.25,P=0.02;substance use disorder OR=1.95,95%CI:1.12-3.38,P=0.01;mood disorder OR=1.16,95%CI:1.05-1.29,P=0.003;and anxiety disorder OR=1.39,95%CI:1.07-1.79,P=0.01.CONCLUSION The study highlights the persistent risk of neurological and psychiatric conditions in COVID-19 survivors up to four years post-infection.Although the incidence was lower than in previous large studies,long-term consequences remain significant,emphasizing the need for ongoing monitoring and support in mental health and neurological care.展开更多
Objectives:Electronic health records(EHRs)offer valuable real-world data(RWD)for Chinese medicine research.However,significant methodological challenges remain in developing integrative Chinese-Western medicine(ICWM)d...Objectives:Electronic health records(EHRs)offer valuable real-world data(RWD)for Chinese medicine research.However,significant methodological challenges remain in developing integrative Chinese-Western medicine(ICWM)databases.This study aims to establish a best-practice methodological framework,referred to as BRIDGE,to guide the construction of ICWM databases using EHRs.Methods:We developed the methodological framework through a comprehensive process,including systematic literature review,synthesis of empirical experiences,thematic expert discussions,and consultation with an external panel to reach consensus.Results:The BRIDGE framework outlines 6 core components for ICWM-EHR database development:Overall design,database architecture,data extraction and linkage,data governance,data verification,and data quality evaluation.Key data elements include variables related to study population,treatment or exposure,outcomes,and confounders.These databases support various research applications,particularly in evaluating the effectiveness and safety of integrative therapies.To demonstrate its practical value,we developed an ICWM-EHR database on women’s reproductive lifespan,encompassing 2,064,482 patients.This database captures women’s health conditions across the life course,from reproductive age to older adulthood.Conclusions:The BRIDGE methodological framework provides a standardized approach to building high-quality ICWM-EHR databases.It offers a unique opportunity to strengthen the methodological rigor and real-world relevance of Chinese medicine research in integrated healthcare settings.展开更多
A new Megaselia species： Megaselia angustirostris Fang ＆ Liu, sp. nov., is described and illustrated and two species of the genus, M. nigra （Meigen） and M. albicaudata （Wood）, are reported for the first time fro...A new Megaselia species： Megaselia angustirostris Fang ＆ Liu, sp. nov., is described and illustrated and two species of the genus, M. nigra （Meigen） and M. albicaudata （Wood）, are reported for the first time from China. The type specimens are deposited in College of Biological and Environmental Engineering, Shenyang University.展开更多
Studies of lithology, sedimentary facies and the distribution regularity of SiO2 and Al2O3 contents and Al2O3/SiO2 ratio allow us to divide the Upper Pleistocene-Holocene Series represented by the MUanggouwan section ...Studies of lithology, sedimentary facies and the distribution regularity of SiO2 and Al2O3 contents and Al2O3/SiO2 ratio allow us to divide the Upper Pleistocene-Holocene Series represented by the MUanggouwan section in China＇s Salawnsu River valley into six segments： MGS1, MGS2, MGS3, MGS4, MGS5 and MGS6. The boundary ages for MGS1 （the Dishaogouwan and Dagouwan Formations）, MGS2 （the upper Chengchuan Formation）, MGS3 （the middle Chengchuan Formation）, MGS4 （the lower Chengchuan Formation）, MGS5 （most strata of the Salawusu Formation） and MGS6 （the bottom of the Salawusu Formation and the top of the Lishi Formation） correspond to those of MIS1, MIS2, MIS3, MIS4, MISS and MIS6, respectively, from deep sea sediments or continental glaciers. MGS5 can be subdivided into five subsegments （MGS5a, MGS5b, MGS5c, MGS5d and MGS5e） and the boundary ages of these subsegments correspond to those of MISSa, MISSb, MIS5c, MIS5d and MIS5e, respectively. Based on the paleoenvironment and paleoecology indicated by the primary chemical elements, fossil vertebrates, mollusks and pollen grains, we hypothesize that MGS1, MGS2, MGS3, MGS4, MGS5 and MGS6 and the subsegments of MGS5 match the corresponding stages for oxygen isotopes in the deep sea sediments and continental glaciers, and the substages of MIS5 in terms of climatic characters, further explaining the phenomena that determined the formation of the late Quaternary strata and the paleontology of the Salawusu River valley. These phenomena relate to fluctuations in the global climate （and particularly in the East Asian monsoon） during the glacial and interglacial periods.展开更多
Guinness Book of World Records(《吉尼期世界纪录在全》) is a famous collection of world records in human life, including many kinds of specific skills. But do you know how the book came out?On November 10, 1951, an Eng...Guinness Book of World Records(《吉尼期世界纪录在全》) is a famous collection of world records in human life, including many kinds of specific skills. But do you know how the book came out?On November 10, 1951, an Englishman, Sir Beveagh, was having a discussion with his friends. They couldn展开更多
The authors analyzed the lead-lag connection of the Atlantic Multidecadal Oscillation (AMO) with East Asian surface air temperatures (EATs) using instrumental records, and compared the results with the Pacific Decadal...The authors analyzed the lead-lag connection of the Atlantic Multidecadal Oscillation (AMO) with East Asian surface air temperatures (EATs) using instrumental records, and compared the results with the Pacific Decadal Oscillation (PDO). The maximum correlation was found when EATs led the AMO by five to seven years (with a correlation coefficient of 0.72, whereas the correlation coefficient was 0.91 when the AMO led EATs by 24-28 years). This is different from the PDO, which mostly correlated with EATs when the PDO led EATs by 13-15 years (with a correlation coefficient of 0.67, whereas the correlation coefficient was 0.76 when EATs led the PDO by 24-26 years). The PDO led the AMO by 19-21 years (with a correlation coefficient of 0.71, whereas the correlation coefficient was 0.84 when the AMO led the PDO by 16-18 years). These results support a previous understanding that EATs positively correlate with the AMO, and imply that the observed East Asian warming trend may have been slowing down since the early 2010s.展开更多
The East China Sea continental shelf is a unique area for the study of land-sea interactions and paleoenvironmental change because it receives a large amount of terrestrial material inputs. In recent decades, human ac...The East China Sea continental shelf is a unique area for the study of land-sea interactions and paleoenvironmental change because it receives a large amount of terrestrial material inputs. In recent decades, human activities and global climate change have greatly aff ected river discharges into the sea. However, changes in the deposition process caused by these factors in the East China Sea continental shelf are unclear. We collected eight short sediment cores from the East China Sea inner shelf(ECSIS) using a box core sampler in 2012 and 2015. The grainsize, 2 10 Pb, and 1 37 Cs of these cores were analyzed in order to reconstruct the deposition history since the 1950 s, and to reveal human activity and climate change influences on sediment deposition in the ECSIS. Results indicated that sediment grain size became finer after 1969, turned coarser after 1987, and then further coarser since 2003, corresponding well to the three steps of sediment load drop in the Changjiang(Yangtze) River, which are mainly caused by human activities(particularly the closure of the Three Gorges Dam). Simultaneously, the East Asian Monsoon influenced the deposition process in the ECSIS by changing the intensity of coastal currents. Mean grain size variations in the fine-grained population(divided by grain size vs. standard deviation method) coincided with that of the East Asian Winter Monsoon strength and reflected its weakness in 1987. Abrupt changes in sediment grain size over a short time scale in these sediment cores were generally caused by floods and typhoons. Spectral analyses of the sediment cores showed periodicities of 10–11 and 20–22 years, corresponding to the periodicity of solar activity(Schwabe cycle and Hale cycle). Mean grain size time series also displayed a 3–8 year periodicity corresponding to El Ni?o Southern Oscillation periodic change.展开更多
Five new species(Gastrochilus yei,Gastrochilus minimus,Luisia simaoensis,Taeniophyllum xizangense,Tuberolabium subulatum)and two newly recorded species(Cleisostoma tricornutum,Luisia inconspicua)of Vandeae(Orchidaceae...Five new species(Gastrochilus yei,Gastrochilus minimus,Luisia simaoensis,Taeniophyllum xizangense,Tuberolabium subulatum)and two newly recorded species(Cleisostoma tricornutum,Luisia inconspicua)of Vandeae(Orchidaceae)from China are described and illustrated.Gastrochilus yei is similar to G.affinis and G.nepalensis,but differs from them by having an epichile not lobed,the apex of the hypochile not bilobed,and a tine on the apex of the leaf.Gastrochilus minimus is similar to G.acinacifolius,but can be distinguished from the latter by having a flabellate epichile that is densely hirsute on the adaxial surface and an inconspicuous central cushion;in addition,the hypochile of G.minimus has a keel that extends to the apex of the epichile.Taeniophyllum xizangense is similar to T.stella and T.radiatum,but it is distinguished from them by having much bigger flowers,inflorescences densely covered with short-bristly hairs,papillae on the external surface of sepals,and bigger triangular-ovate viscidium.Luisia simaoensis is similar to L magniflora and L ramosii,but can be easily distinguished from them by having lateral sepals longer than dorsal sepals and petals,lip with irregular and waved margins,and lip with bilobed apex.Luisia inconspicua is moved from Gastrochilus to Luisia based on phylogenetic analyses of plastid matK sequence data.Tuberolabium subulatum is similar to T.camosum,but it can be easily distinguished from the latter by having an inflorescence much shorter than the leaves,yellow sepals and petals,and many small papillae outside the lip lobes.展开更多
Columbia(Nuna)is a Paleo-Mesoproterozoic supercontinent that was assembled during global 2.0–1.8Ga collisional events,underwent long-lived,subductionrelated accretion at key continental margins in the period
The early Albian Oceanic Anoxic Event 1 b(OAE 1 b) is well documented in the Tethys, Pacific and North Atlantic, but few studies have evaluated whether or not terrestrial records of OAE 1 b exist. In order to identify...The early Albian Oceanic Anoxic Event 1 b(OAE 1 b) is well documented in the Tethys, Pacific and North Atlantic, but few studies have evaluated whether or not terrestrial records of OAE 1 b exist. In order to identify terrestrial records of the early Albian OAE 1 b and to infer possible driving mechanisms, an integrated multi-proxy study from the late Aptian to Albian in the Fuxin lacustrine basin was conducted,including thick, organic-rich black mudstones, total organic carbon(TOC), organic carbon isotopes(d13 Corg), mercury concentration(Hg) and results from pyrolysis analyses(S2, Tmaxand HI). Results show three distinct short-term negative d13 Corgexcursions corresponding with relatively high TOC values,which could be counterparts of the Kilian, Paquier and Leenhardt sub-events of the early Albian OAE1 b. Atmospheric CO2 concentration(p CO2) recovered from C3 plant d13 Corgcompositions indicates an increasing trend in Unit C during the early Albian, and there are three short-term increases of p CO2 corresponding to the three sub-events of OAE 1 b at this time interval. We infer that a trend of increasing p CO2 during the Kilian sub-event in the study area is closely related to volcanism. Continental weathering calculated using chemical weathering indices(CIA, WIP and MIA(O)) show an increasing trend during the OAE 1 b interval, likely resulting from warmer and more humid conditions. Mixed sources of terrestrial plants and lacustrine plankton demonstrated by pyrolysis analyses(HI vs. Tmaxand S2 vs. TOC), indicate a terrestrial contribution to the organic-rich sediments of the Kilian, Paquier and Leenhardt sub-events of OAE 1 b. We suggest that a CO2-forced greenhouse effect during the early Albian might have triggered the relatively warm and humid palaeoclimatic conditions, and intensified chemical weathering that combined to create high nutrient and organic matter levels that were flushed into lakes contributing to eutrophication and anoxia in lacustrine and in contemporaneous oceanic systems.展开更多
Three species of Lumbrineridae, Helmutnerisflabellicola （Fage, 1936）, Lurnbrinerides dayi Perkins, 1979, and Ninoe japonica Imajima ＆ Higuchi, 1975, are reported from the material collected between 1959 and 1994 fr...Three species of Lumbrineridae, Helmutnerisflabellicola （Fage, 1936）, Lurnbrinerides dayi Perkins, 1979, and Ninoe japonica Imajima ＆ Higuchi, 1975, are reported from the material collected between 1959 and 1994 from the Yellow Sea, East China Sea, and South China Sea. These species are not previously recorded from Chinese waters. Systematic descriptions and morphological illustrations of the species are provided in this paper.展开更多
Five species of free-living marine nematodes are redescribed and illustrated as new records in the Yellow Sea of China. These species include one monhysterid, Campylaimus gerlachi in the family Diplopeltidae and four ...Five species of free-living marine nematodes are redescribed and illustrated as new records in the Yellow Sea of China. These species include one monhysterid, Campylaimus gerlachi in the family Diplopeltidae and four enoplids species, Oxystomina elongata, Oxystomina elegans, Halalaimus lutarus and Halalaimus wodjanizkii in the family Oxystominidae. Ecological and taxonomic remarks are provided and discussed in comparison with the original description. The key to all known species of the genus Campylaimus is given. Our findings have offerred the taxonomic information of nematodes to the benthic ecology and biodiversity studies of the Yellow Sea.展开更多
This research uses eigenvalue characteristics of nonlinear principal component analysis （NLPCA） and principal component analysis （PCA） to investigate total electron content （TEC） anomalies associated with Taiwan...This research uses eigenvalue characteristics of nonlinear principal component analysis （NLPCA） and principal component analysis （PCA） to investigate total electron content （TEC） anomalies associated with Taiwan＇s Chi-Chi earthquake of 21 September 1999 （LT） （M_w=7.6）. The transforms are used for ionospheric TEC from 01 August to 20 September 1999 （local time） using data from 13 GPS receivers. The data were collected at 22°N-26°N Lat. and 120°E-122°E Long.. Applying the NLPCA to the multi-channel total electron content records of GPS receivers, the earthquake-associated TEC anomalies were represented by large principal eigenvalues of NLPCA （〉0.5 in a normalized set） on 14 August and 17, 18, and 20 September, with allowance given for the Dst index, which was quiet for the study period. Comparisons were then made with other researchers who also found TEC anomalies on September 17, 18, and 19 associated with the Chi-Chi earthquake, which cannot be detected by PCA.Consideration is also given for reported ground level geomagnetic field activity that occurred between mid-August and late October, leading up to and including the Chi-Chi and Chia-Yi earthquakes, which are associated with the same series of faults. It is possible that Aug. 14 is representative of an earthquake-associated TEC anomaly. This is an interesting result given how much earlier than the earthquake it occurred.展开更多
Background:Electronic Health Record(EHR)systems are used as an efficient and effective technique for sharing patient’s health records among different hospitals and various other key stakeholders of the healthcare ind...Background:Electronic Health Record(EHR)systems are used as an efficient and effective technique for sharing patient’s health records among different hospitals and various other key stakeholders of the healthcare industry to achieve better diagnosis and treatment of patients globally.However,the existing EHR systems mostly lack in providing appropriate security,entrusted access control and handling privacy and secrecy issues and challenges in current hospital infrastructures.Objective:To solve this delicate problem,we propose a Blockchain-enabled Hyperledger Fabric Architecture for different EHR systems.Methodology:In our EHR blockchain system,Peer nodes from various organizations(stakeholders)create a ledger network,where channels are created to enable secure and private communication between different stakeholders on the ledger network.Individual patients and other stakeholders are identified and registered on the network by unique digital certificates issued by membership service provider(MSP)component of the fabric architecture.Results:We created and implemented different Chaincodes to handle the business logic for executing separate EHR transactions on the network.The proposed fabric architecture provides a secure,transparent and immutable mechanism to store,share and exchange EHRs in a peer-to-peer network of different healthcare stakeholders.It ensures interoperability,scalability and availability in adapting the existing EHRs for strengthening and providing an effective and secure method to integrate and manage patient records among medical institutions in the healthcare ecosystem.展开更多
Six species of new records collected from intertidal mangrove/non-mangrove and subtidal cave sediments during a mangrove ecological study (1998-2001) and a marine cave expedition (2002) in Hong Kong waters are redescr...Six species of new records collected from intertidal mangrove/non-mangrove and subtidal cave sediments during a mangrove ecological study (1998-2001) and a marine cave expedition (2002) in Hong Kong waters are redescribed. These include two enoplids: Anoplostoma viviparum in Anoplostomatidae and Trissonchulus janetae in Ironidae, two chromadorids:Paracomesoma dubium and Actarjania splendens in Comesomatidae, and two monhysterids: Parodontophora marina and Parodontophora c.f. danker in Axonolaimidae. Five of them are the first records from China. Ecological and taxonomic remarks are provided and discussed in comparison with the original descriptions.展开更多
In the existing Electronic Health Records(EHRs),the medical information of patients is completely controlled by various medical institutions.As such,patients have no dominant power over their own EHRs.These personal d...In the existing Electronic Health Records(EHRs),the medical information of patients is completely controlled by various medical institutions.As such,patients have no dominant power over their own EHRs.These personal data are not only inconvenient to access and share,but are also prone to cause privacy disclosure.The blockchain technology provides a new development direction in the medical field.Blockchain-based EHRs are characterized by decentralization,openness and non-tampering of records,which enable patients to better manage their own EHRs.In order to better protect the privacy of patients,only designated receivers can access EHRs,and receivers can authenticate the sharer to ensure that the EHRs are real and effective.In this study,we propose an identity-based signcryption scheme with multiple authorities for multiple receivers,which can resist N-1 collusion attacks among N authorities.In addition,the identity information of receivers is anonymous,so the relationship between them and the sharer is not disclosed.Under the random oracle model,it was proved that our scheme was secure and met the unforgeability and confidentiality requirements of signcryption.Moreover,we evaluated the performance of the scheme and found that it had the moderate signcryption efficiency and excellent signcryption attributes.展开更多
A preliminary study on the advance and the retreat of Qingtu Lake and its climatic records of the Holocene lacustrine deposits has been made through comprehensive analysis. The study shows that the modes characteristi...A preliminary study on the advance and the retreat of Qingtu Lake and its climatic records of the Holocene lacustrine deposits has been made through comprehensive analysis. The study shows that the modes characteristics of climatic change in Eastern Hexi Corridor was provided with the corresponding relationship of warm moist and cold dry during the scale longer than hundred years. As a result of climatic changes and human activities, Qingtu Lake cycle has undergone four lake retreated and three lake advanced stages since 6000 a B.P. Based on the study on lacustrine sedimentary color, grain size, Fe 3+ /Fe 2+ and organic matter, the authors put forward that a warm period existed during the phase of 335-480 A.D. in the studied area. This warm period could be further testified by a lot of evidences obtained from the historical documents and the natural records of Qingtu Lake. In brief, the evolution of lakes in Eastern Hexi Corridor is characterized by sedimentary continuity, fast sedimentary rate and high resolution, it not only indicate the paleoenvironmental and climatic change in Holocene, but also can reflect the intensity of Eastern Asia monsoon.展开更多
The parameter estimation is considered for the Gompertz distribution under frequensitst and Bayes approaches when records are available.Maximum likelihood estimators,exact and approximate confidence intervals are deve...The parameter estimation is considered for the Gompertz distribution under frequensitst and Bayes approaches when records are available.Maximum likelihood estimators,exact and approximate confidence intervals are developed for the model parameters,and Bayes estimators of reliability performances are obtained under different losses based on a mixture of continuous and discrete priors.To investigate the performance of the proposed estimators,a record simulation algorithm is provided and a numerical study is presented by using Monte-Carlo simulation.展开更多
文摘Savannah,Ga.,April 22,2025-Gulfstream Aerospace Corp.today announced its fleet has achieved an industry-leading 700 city-pair speed records with a Gulfstream G700 flight from Taipei to Miami.This flight commemorates the 50-year anniversary of Gulfstream's first U.S.National Aeronautic Association(NAA)accredited speed record,set in 1975 by the Gulfstream GII.
基金supported by grants from the National Natural Science Foundation of China(Grant No.32271733)Guangdong Basic and Applied Basic Research Foundation(Grant No.2023A1515011045)+1 种基金Science and Technology Projects in Guangzhou(Grant No.2023A04J0121)SCNU Training Program of Innovation for Undergraduates,China。
文摘Anthropogenic climate change is altering species distributions globally.While species distributions are expected to shift to higher latitudes and elevations under global warming,empirical evidence on distribution shifts is mixed,and factors mediating the direction and magnitude of range shifts remain unclear.Using a dataset of 132new provincial records for 96 resident bird species from 2000 to 2023,we measured geographic distance,latitudinal shift,and temperature shift from each new record to the historical range for each species to test for poleward shifts.We assessed taxonomic variation in the magnitude of range shifts and used phylogenetic generalized linear mixed models to quantify relationships between species traits and the extent of range shifts.Our results revealed that new records occurred at a mean geographic distance of 420 km from historical ranges,with mean latitudinal shifts of+1.68°(poleward)and temperature shifts of-1.33℃(toward colder climates).The magnitude of geographic range shifts was strongly constrained by phylogenetic relatedness.Habitat breadth,habitat openness,and centroid latitude of historical ranges emerged as significant predictors of range shifts.Our results suggest that resident bird species'geographic ranges in China are shifting poleward,but the magnitude of these shifts is non-random across lineages.Species with broader habitat preferences and those from warmer climates are more likely to shift farther from their historical ranges and toward higher latitudes.This study emphasizes taxonomic variation in species range shifts and highlights the need for species-and site-specific conservation strategies under global warming.
文摘BACKGROUND The neurological and psychiatric sequelae of coronavirus disease 2019(COVID-19)have been documented,yet further data are needed to thoroughly evaluate the impact of COVID-19 on brain health years after the infection.AIM To examine whether COVID-19 infection is associated with exacerbation,recurrence,or progression of pre-existing neurological or psychiatric disorders-a highrisk population that is underrepresented in COVID-19 outcome research in National Guard Health Affair patients in 4-years following a COVID-19 diagnosis.METHODS For this multicenter retrospective cohort study,we used data from the National Guard hospitals electronic health records network(BestCare)with over 10 million patients.Our cohort comprised patients who had a COVID-19 diagnosis;a matched control cohort included patient did not expose to COVID-19 in same period.Age and sex were matching factors.We estimated the incidence of 14 neurological and psychiatric outcomes in nearly 4 years after a confirmed diagnosis of COVID-19.Using a multiple logistic regression,we compared incidences with those in propensity score-matched cohorts of patients with no exposure to COVID-19.Ramadan M et al.Neurological and psychiatric risks post-COVID-19 RESULTS Our primary cohort comprised 4437 patients diagnosed with COVID-19,and our propensity-score 1:1 matched control cohort comprised 4437 individuals.Nearly two-third of the COVID-19 cohort(71%)were diagnosed in 2020,and 2021.The most prevalent diagnoses for both cohorts were epilepsy 30.68%,mood disorder 23.92%,and nerve plexus disorder 22.13%.Dementia was nearly 4 times higher among COVID-19 cohort(8.27%)compared to the control cohort(2.57%).Five neurological and psychiatric outcomes had odds ratios(OR)that were significantly higher than 1 for people who had COVID-19 compared to people who had never been infected.These outcomes were cognitive deficit OR=1.54,95%confidence interval(CI):1.23-1.91,P=0.0001;nerve plexus disorder OR=1.13,95%CI:1.01-1.25,P=0.02;substance use disorder OR=1.95,95%CI:1.12-3.38,P=0.01;mood disorder OR=1.16,95%CI:1.05-1.29,P=0.003;and anxiety disorder OR=1.39,95%CI:1.07-1.79,P=0.01.CONCLUSION The study highlights the persistent risk of neurological and psychiatric conditions in COVID-19 survivors up to four years post-infection.Although the incidence was lower than in previous large studies,long-term consequences remain significant,emphasizing the need for ongoing monitoring and support in mental health and neurological care.
基金supported by the National Key Research&Development Program of China(No.2024YFC3505800)the National Natural Science Foundation of China(Nos.82474334,82474335 and 72174132)+3 种基金National Science Fund for Distinguished Young Scholars(No.82225049)the Key Research&Development Projects of Sichuan Provincial Department of Science and Technology(Nos.2024YFFK0174 and 2024YFFK0152)1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(Nos.ZYYC24010 and ZYGD23004)the Special Fund for Traditional Chinese Medicine of Sichuan Provincial Administration of Traditional Chinese Medicine(No.2024zd023).
文摘Objectives:Electronic health records(EHRs)offer valuable real-world data(RWD)for Chinese medicine research.However,significant methodological challenges remain in developing integrative Chinese-Western medicine(ICWM)databases.This study aims to establish a best-practice methodological framework,referred to as BRIDGE,to guide the construction of ICWM databases using EHRs.Methods:We developed the methodological framework through a comprehensive process,including systematic literature review,synthesis of empirical experiences,thematic expert discussions,and consultation with an external panel to reach consensus.Results:The BRIDGE framework outlines 6 core components for ICWM-EHR database development:Overall design,database architecture,data extraction and linkage,data governance,data verification,and data quality evaluation.Key data elements include variables related to study population,treatment or exposure,outcomes,and confounders.These databases support various research applications,particularly in evaluating the effectiveness and safety of integrative therapies.To demonstrate its practical value,we developed an ICWM-EHR database on women’s reproductive lifespan,encompassing 2,064,482 patients.This database captures women’s health conditions across the life course,from reproductive age to older adulthood.Conclusions:The BRIDGE methodological framework provides a standardized approach to building high-quality ICWM-EHR databases.It offers a unique opportunity to strengthen the methodological rigor and real-world relevance of Chinese medicine research in integrated healthcare settings.
基金supported by the National Natural Science Foundation of China(30270187)
文摘A new Megaselia species： Megaselia angustirostris Fang ＆ Liu, sp. nov., is described and illustrated and two species of the genus, M. nigra （Meigen） and M. albicaudata （Wood）, are reported for the first time from China. The type specimens are deposited in College of Biological and Environmental Engineering, Shenyang University.
基金This study was supported by the National Basic Research Program of China （No. 2004CB720206） the National Natural Science Foundation of China （No. 49971009）the RGC （HKU 7243/04H） Grant of the HKSAR and the Chinese Academy of Sciences （No. KZCX2-SW-118）
文摘Studies of lithology, sedimentary facies and the distribution regularity of SiO2 and Al2O3 contents and Al2O3/SiO2 ratio allow us to divide the Upper Pleistocene-Holocene Series represented by the MUanggouwan section in China＇s Salawnsu River valley into six segments： MGS1, MGS2, MGS3, MGS4, MGS5 and MGS6. The boundary ages for MGS1 （the Dishaogouwan and Dagouwan Formations）, MGS2 （the upper Chengchuan Formation）, MGS3 （the middle Chengchuan Formation）, MGS4 （the lower Chengchuan Formation）, MGS5 （most strata of the Salawusu Formation） and MGS6 （the bottom of the Salawusu Formation and the top of the Lishi Formation） correspond to those of MIS1, MIS2, MIS3, MIS4, MISS and MIS6, respectively, from deep sea sediments or continental glaciers. MGS5 can be subdivided into five subsegments （MGS5a, MGS5b, MGS5c, MGS5d and MGS5e） and the boundary ages of these subsegments correspond to those of MISSa, MISSb, MIS5c, MIS5d and MIS5e, respectively. Based on the paleoenvironment and paleoecology indicated by the primary chemical elements, fossil vertebrates, mollusks and pollen grains, we hypothesize that MGS1, MGS2, MGS3, MGS4, MGS5 and MGS6 and the subsegments of MGS5 match the corresponding stages for oxygen isotopes in the deep sea sediments and continental glaciers, and the substages of MIS5 in terms of climatic characters, further explaining the phenomena that determined the formation of the late Quaternary strata and the paleontology of the Salawusu River valley. These phenomena relate to fluctuations in the global climate （and particularly in the East Asian monsoon） during the glacial and interglacial periods.
文摘Guinness Book of World Records(《吉尼期世界纪录在全》) is a famous collection of world records in human life, including many kinds of specific skills. But do you know how the book came out?On November 10, 1951, an Englishman, Sir Beveagh, was having a discussion with his friends. They couldn
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA05090406)the special projects of China Meteorological Administration(Grant No.GYHY201006022)
文摘The authors analyzed the lead-lag connection of the Atlantic Multidecadal Oscillation (AMO) with East Asian surface air temperatures (EATs) using instrumental records, and compared the results with the Pacific Decadal Oscillation (PDO). The maximum correlation was found when EATs led the AMO by five to seven years (with a correlation coefficient of 0.72, whereas the correlation coefficient was 0.91 when the AMO led EATs by 24-28 years). This is different from the PDO, which mostly correlated with EATs when the PDO led EATs by 13-15 years (with a correlation coefficient of 0.67, whereas the correlation coefficient was 0.76 when EATs led the PDO by 24-26 years). The PDO led the AMO by 19-21 years (with a correlation coefficient of 0.71, whereas the correlation coefficient was 0.84 when the AMO led the PDO by 16-18 years). These results support a previous understanding that EATs positively correlate with the AMO, and imply that the observed East Asian warming trend may have been slowing down since the early 2010s.
基金Supported by the National Natural Science Foundation of China(No.41430965)the Open Fund of the Key Laboratory of Marine Geology and Environment,Chinese Academy of Sciences(No.MGE2015KG08)
文摘The East China Sea continental shelf is a unique area for the study of land-sea interactions and paleoenvironmental change because it receives a large amount of terrestrial material inputs. In recent decades, human activities and global climate change have greatly aff ected river discharges into the sea. However, changes in the deposition process caused by these factors in the East China Sea continental shelf are unclear. We collected eight short sediment cores from the East China Sea inner shelf(ECSIS) using a box core sampler in 2012 and 2015. The grainsize, 2 10 Pb, and 1 37 Cs of these cores were analyzed in order to reconstruct the deposition history since the 1950 s, and to reveal human activity and climate change influences on sediment deposition in the ECSIS. Results indicated that sediment grain size became finer after 1969, turned coarser after 1987, and then further coarser since 2003, corresponding well to the three steps of sediment load drop in the Changjiang(Yangtze) River, which are mainly caused by human activities(particularly the closure of the Three Gorges Dam). Simultaneously, the East Asian Monsoon influenced the deposition process in the ECSIS by changing the intensity of coastal currents. Mean grain size variations in the fine-grained population(divided by grain size vs. standard deviation method) coincided with that of the East Asian Winter Monsoon strength and reflected its weakness in 1987. Abrupt changes in sediment grain size over a short time scale in these sediment cores were generally caused by floods and typhoons. Spectral analyses of the sediment cores showed periodicities of 10–11 and 20–22 years, corresponding to the periodicity of solar activity(Schwabe cycle and Hale cycle). Mean grain size time series also displayed a 3–8 year periodicity corresponding to El Ni?o Southern Oscillation periodic change.
基金supported by Grant from National Forestry and Grassland Administration(No.2019073018,2019073019,2019073002,2019073003)Science and Technology Basic Resources Investigation Program of China"Survey and Germplasm Conservation of Plant Species with Extremely Small Populations in South-west China"(Grant No.2017FY100100)+3 种基金National Natural Science Foundation of China(No.31870195)Strategic Biological Resources Capacity Building Project from the Chinese Academy of Sciences"Seed Plants Research in Xishuangbanna Karst Region"(Grant No.KFJ-BRP-017-36)the Large-scale Scientific Facilities of the Chinese Academy of Sciences(Grant No.2017-LSFGBOWS-02)the National Wild Plant Germplasm Resource Center,National Science&Technology Infrastructure。
文摘Five new species(Gastrochilus yei,Gastrochilus minimus,Luisia simaoensis,Taeniophyllum xizangense,Tuberolabium subulatum)and two newly recorded species(Cleisostoma tricornutum,Luisia inconspicua)of Vandeae(Orchidaceae)from China are described and illustrated.Gastrochilus yei is similar to G.affinis and G.nepalensis,but differs from them by having an epichile not lobed,the apex of the hypochile not bilobed,and a tine on the apex of the leaf.Gastrochilus minimus is similar to G.acinacifolius,but can be distinguished from the latter by having a flabellate epichile that is densely hirsute on the adaxial surface and an inconspicuous central cushion;in addition,the hypochile of G.minimus has a keel that extends to the apex of the epichile.Taeniophyllum xizangense is similar to T.stella and T.radiatum,but it is distinguished from them by having much bigger flowers,inflorescences densely covered with short-bristly hairs,papillae on the external surface of sepals,and bigger triangular-ovate viscidium.Luisia simaoensis is similar to L magniflora and L ramosii,but can be easily distinguished from them by having lateral sepals longer than dorsal sepals and petals,lip with irregular and waved margins,and lip with bilobed apex.Luisia inconspicua is moved from Gastrochilus to Luisia based on phylogenetic analyses of plastid matK sequence data.Tuberolabium subulatum is similar to T.camosum,but it can be easily distinguished from the latter by having an inflorescence much shorter than the leaves,yellow sepals and petals,and many small papillae outside the lip lobes.
文摘Columbia(Nuna)is a Paleo-Mesoproterozoic supercontinent that was assembled during global 2.0–1.8Ga collisional events,underwent long-lived,subductionrelated accretion at key continental margins in the period
基金supported by the Yue Qi Scholar Project of China University of Mining and Technology(Beijing)Chinathe National Natural Science Foundation of China(41572090+1 种基金42002128)Shandong Key Laboratory of Depositional Mineralization&Sedimentary Mineral Shandong University of Science and Technology China(DMSM20190015)。
文摘The early Albian Oceanic Anoxic Event 1 b(OAE 1 b) is well documented in the Tethys, Pacific and North Atlantic, but few studies have evaluated whether or not terrestrial records of OAE 1 b exist. In order to identify terrestrial records of the early Albian OAE 1 b and to infer possible driving mechanisms, an integrated multi-proxy study from the late Aptian to Albian in the Fuxin lacustrine basin was conducted,including thick, organic-rich black mudstones, total organic carbon(TOC), organic carbon isotopes(d13 Corg), mercury concentration(Hg) and results from pyrolysis analyses(S2, Tmaxand HI). Results show three distinct short-term negative d13 Corgexcursions corresponding with relatively high TOC values,which could be counterparts of the Kilian, Paquier and Leenhardt sub-events of the early Albian OAE1 b. Atmospheric CO2 concentration(p CO2) recovered from C3 plant d13 Corgcompositions indicates an increasing trend in Unit C during the early Albian, and there are three short-term increases of p CO2 corresponding to the three sub-events of OAE 1 b at this time interval. We infer that a trend of increasing p CO2 during the Kilian sub-event in the study area is closely related to volcanism. Continental weathering calculated using chemical weathering indices(CIA, WIP and MIA(O)) show an increasing trend during the OAE 1 b interval, likely resulting from warmer and more humid conditions. Mixed sources of terrestrial plants and lacustrine plankton demonstrated by pyrolysis analyses(HI vs. Tmaxand S2 vs. TOC), indicate a terrestrial contribution to the organic-rich sediments of the Kilian, Paquier and Leenhardt sub-events of OAE 1 b. We suggest that a CO2-forced greenhouse effect during the early Albian might have triggered the relatively warm and humid palaeoclimatic conditions, and intensified chemical weathering that combined to create high nutrient and organic matter levels that were flushed into lakes contributing to eutrophication and anoxia in lacustrine and in contemporaneous oceanic systems.
基金Supported by the Knowledge Innovation Program of the Chinese Academy of Sciences(No.O72715)
文摘Three species of Lumbrineridae, Helmutnerisflabellicola （Fage, 1936）, Lurnbrinerides dayi Perkins, 1979, and Ninoe japonica Imajima ＆ Higuchi, 1975, are reported from the material collected between 1959 and 1994 from the Yellow Sea, East China Sea, and South China Sea. These species are not previously recorded from Chinese waters. Systematic descriptions and morphological illustrations of the species are provided in this paper.
文摘Five species of free-living marine nematodes are redescribed and illustrated as new records in the Yellow Sea of China. These species include one monhysterid, Campylaimus gerlachi in the family Diplopeltidae and four enoplids species, Oxystomina elongata, Oxystomina elegans, Halalaimus lutarus and Halalaimus wodjanizkii in the family Oxystominidae. Ecological and taxonomic remarks are provided and discussed in comparison with the original description. The key to all known species of the genus Campylaimus is given. Our findings have offerred the taxonomic information of nematodes to the benthic ecology and biodiversity studies of the Yellow Sea.
文摘This research uses eigenvalue characteristics of nonlinear principal component analysis （NLPCA） and principal component analysis （PCA） to investigate total electron content （TEC） anomalies associated with Taiwan＇s Chi-Chi earthquake of 21 September 1999 （LT） （M_w=7.6）. The transforms are used for ionospheric TEC from 01 August to 20 September 1999 （local time） using data from 13 GPS receivers. The data were collected at 22°N-26°N Lat. and 120°E-122°E Long.. Applying the NLPCA to the multi-channel total electron content records of GPS receivers, the earthquake-associated TEC anomalies were represented by large principal eigenvalues of NLPCA （〉0.5 in a normalized set） on 14 August and 17, 18, and 20 September, with allowance given for the Dst index, which was quiet for the study period. Comparisons were then made with other researchers who also found TEC anomalies on September 17, 18, and 19 associated with the Chi-Chi earthquake, which cannot be detected by PCA.Consideration is also given for reported ground level geomagnetic field activity that occurred between mid-August and late October, leading up to and including the Chi-Chi and Chia-Yi earthquakes, which are associated with the same series of faults. It is possible that Aug. 14 is representative of an earthquake-associated TEC anomaly. This is an interesting result given how much earlier than the earthquake it occurred.
基金funded by the Deanship of Scientific Research at Princess Nourah bint Abdulrahman University through the Fast-track Research Funding Program.
文摘Background:Electronic Health Record(EHR)systems are used as an efficient and effective technique for sharing patient’s health records among different hospitals and various other key stakeholders of the healthcare industry to achieve better diagnosis and treatment of patients globally.However,the existing EHR systems mostly lack in providing appropriate security,entrusted access control and handling privacy and secrecy issues and challenges in current hospital infrastructures.Objective:To solve this delicate problem,we propose a Blockchain-enabled Hyperledger Fabric Architecture for different EHR systems.Methodology:In our EHR blockchain system,Peer nodes from various organizations(stakeholders)create a ledger network,where channels are created to enable secure and private communication between different stakeholders on the ledger network.Individual patients and other stakeholders are identified and registered on the network by unique digital certificates issued by membership service provider(MSP)component of the fabric architecture.Results:We created and implemented different Chaincodes to handle the business logic for executing separate EHR transactions on the network.The proposed fabric architecture provides a secure,transparent and immutable mechanism to store,share and exchange EHRs in a peer-to-peer network of different healthcare stakeholders.It ensures interoperability,scalability and availability in adapting the existing EHRs for strengthening and providing an effective and secure method to integrate and manage patient records among medical institutions in the healthcare ecosystem.
基金funded by National Key Basic Research Program from the Ministry of Science and Technology,People’s Repubfic of China(G 19990437)also supported by the National Natural Science Foundation of China(No.40176033)
文摘Six species of new records collected from intertidal mangrove/non-mangrove and subtidal cave sediments during a mangrove ecological study (1998-2001) and a marine cave expedition (2002) in Hong Kong waters are redescribed. These include two enoplids: Anoplostoma viviparum in Anoplostomatidae and Trissonchulus janetae in Ironidae, two chromadorids:Paracomesoma dubium and Actarjania splendens in Comesomatidae, and two monhysterids: Parodontophora marina and Parodontophora c.f. danker in Axonolaimidae. Five of them are the first records from China. Ecological and taxonomic remarks are provided and discussed in comparison with the original descriptions.
基金This work was supported by the National Key Research and Development Project of China(Grant No.2017YFB0802302)the Science and Technology Support Project of Sichuan Province(Grant Nos.2016FZ0112,2017GZ0314,and 2018GZ0204)+2 种基金the Academic and Technical Leaders Training Funding Support Projects of Sichuan Province(Grant No.2016120080102643)the Application Foundation Project of Sichuan Province(Grant No.2017JY0168)the Science and Technology Project of Chengdu(Grant Nos.2017-RK00-00103-ZF,and 2016-HM01-00217-SF).
文摘In the existing Electronic Health Records(EHRs),the medical information of patients is completely controlled by various medical institutions.As such,patients have no dominant power over their own EHRs.These personal data are not only inconvenient to access and share,but are also prone to cause privacy disclosure.The blockchain technology provides a new development direction in the medical field.Blockchain-based EHRs are characterized by decentralization,openness and non-tampering of records,which enable patients to better manage their own EHRs.In order to better protect the privacy of patients,only designated receivers can access EHRs,and receivers can authenticate the sharer to ensure that the EHRs are real and effective.In this study,we propose an identity-based signcryption scheme with multiple authorities for multiple receivers,which can resist N-1 collusion attacks among N authorities.In addition,the identity information of receivers is anonymous,so the relationship between them and the sharer is not disclosed.Under the random oracle model,it was proved that our scheme was secure and met the unforgeability and confidentiality requirements of signcryption.Moreover,we evaluated the performance of the scheme and found that it had the moderate signcryption efficiency and excellent signcryption attributes.
文摘A preliminary study on the advance and the retreat of Qingtu Lake and its climatic records of the Holocene lacustrine deposits has been made through comprehensive analysis. The study shows that the modes characteristics of climatic change in Eastern Hexi Corridor was provided with the corresponding relationship of warm moist and cold dry during the scale longer than hundred years. As a result of climatic changes and human activities, Qingtu Lake cycle has undergone four lake retreated and three lake advanced stages since 6000 a B.P. Based on the study on lacustrine sedimentary color, grain size, Fe 3+ /Fe 2+ and organic matter, the authors put forward that a warm period existed during the phase of 335-480 A.D. in the studied area. This warm period could be further testified by a lot of evidences obtained from the historical documents and the natural records of Qingtu Lake. In brief, the evolution of lakes in Eastern Hexi Corridor is characterized by sedimentary continuity, fast sedimentary rate and high resolution, it not only indicate the paleoenvironmental and climatic change in Holocene, but also can reflect the intensity of Eastern Asia monsoon.
基金supported by the National Natural Science Foundation of China(1150143371473187)+1 种基金the Fundamental Research Funds for the Central Universities(JB1507177215591806)
文摘The parameter estimation is considered for the Gompertz distribution under frequensitst and Bayes approaches when records are available.Maximum likelihood estimators,exact and approximate confidence intervals are developed for the model parameters,and Bayes estimators of reliability performances are obtained under different losses based on a mixture of continuous and discrete priors.To investigate the performance of the proposed estimators,a record simulation algorithm is provided and a numerical study is presented by using Monte-Carlo simulation.
