Personal video recorders (PVRs) have altered the way users consume television (TV) content by allowing users to record programs and watch them at their convenience, overcoming the constraints of live broadcasting. How...Personal video recorders (PVRs) have altered the way users consume television (TV) content by allowing users to record programs and watch them at their convenience, overcoming the constraints of live broadcasting. However, standalone PVRs are limited by their individual storage capacities, restricting the number of programs they can store. While online catch-up TV services such as Hulu and Netflix mitigate this limitation by offering on-demand access to broadcast programs shortly after their initial broadcast, they require substantial storage and network resources, leading to significant infrastructural costs for service providers. To address these challenges, we propose a collaborative TV content recording system that leverages distributed PVRs, combining their storage into a virtual shared pool without additional costs. Our system aims to support all concurrent playback requests without service interruption while ensuring program availability comparable to that of local devices. The main contributions of our proposed system are fourfold. First, by sharing storage and upload bandwidth among PVRs, our system significantly expands the overall recording capacity and enables simultaneous recording of multiple programs without the physical constraints of standalone devices. Second, by utilizing erasure coding efficiently, our system reduces the storage space required for each program, allowing more programs to be recorded compared to traditional replication. Third, we propose an adaptive redundancy scheme to control the degree of redundancy of each program based on its evolving playback demand, ensuring high-quality playback by providing sufficient bandwidth for popular programs. Finally, we introduce a contribution-based incentive policy that encourages PVRs to actively participate by contributing resources, while discouraging excessive consumption of the combined storage pool. Through extensive experiments, we demonstrate the effectiveness of our proposed collaborative TV program recording system in terms of storage efficiency and performance.展开更多
Bit-Pattemed Magnetic Recording(BPMR)is one of the emerging data storage technologies,which promises an Areal Density(AD)of about 4 Tb/in2.However,a major problem practically encountered in a BPMR system is Inter-Trac...Bit-Pattemed Magnetic Recording(BPMR)is one of the emerging data storage technologies,which promises an Areal Density(AD)of about 4 Tb/in2.However,a major problem practically encountered in a BPMR system is Inter-Track Interference(ITI)that can deteriorate the overall system performance,especially at high ADs.This paper proposes an iterative ITI cancellation method for an m-head m-track BPMR system,which uses m heads to read m adjacent tracks and decodes them simultaneously.To cancel the ITI,we subtract the weighted readback signals of adjacent tracks,acting as the ITI signals,from the readback signal of the target track,before passing the refined readback signal to a turbo decoder.Then,the decoded data will be employed to reconstruct the ITI signal for the next turbo iteration.Experimental results indicate that the proposed system performs better than the conventional system that uses one head to read one data track.Furthermore,we also find out that the proposed system is more robust to media noise and track misregistration than the conventional system.展开更多
In this paper a fault location and recording system based on a computer network is presented. A brief description of the system structure and main features are given. Emphasis is placed on the accurate fault location ...In this paper a fault location and recording system based on a computer network is presented. A brief description of the system structure and main features are given. Emphasis is placed on the accurate fault location method for extra high voltage and long distance transmission lines.展开更多
Cyber-Physical System (CPS) devices are increasing exponentially. Lacking confidentiality creates a vulnerable network. Thus, demanding the overall system with the latest and robust solutions for the defence mechanism...Cyber-Physical System (CPS) devices are increasing exponentially. Lacking confidentiality creates a vulnerable network. Thus, demanding the overall system with the latest and robust solutions for the defence mechanisms with low computation cost, increased integrity, and surveillance. The proposal of a mechanism that utilizes the features of authenticity measures using the Destination Sequence Distance Vector (DSDV) routing protocol which applies to the multi-WSN (Wireless Sensor Network) of IoT devices in CPS which is developed for the Device-to-Device (D2D) authentication developed from the local-chain and public chain respectively combined with the Software Defined Networking (SDN) control and monitoring system using switches and controllers that will route the packets through the network, identify any false nodes, take preventive measures against them and preventing them for any future problems. Next, the system is powered by Blockchain cryptographic features by utilizing the TrustChain features to create a private, secure, and temper-free ledger of the transactions performed inside the network. Results are achieved in the legitimate devices connecting to the network, transferring their packets to their destination under supervision, reporting whenever a false node is causing hurdles, and recording the transactions for temper-proof records. Evaluation results based on 1000+ transactions illustrate that the proposed mechanism not only outshines most aspects of Cyber-Physical systems but also consumes less computation power with a low latency of 0.1 seconds only.展开更多
This paper presents the design of a low-power multi-channel analog front-end(AFE) for bio-potential recording. By using time division multiplexing(TDM), a successive approximation register analog-to-digital converter(...This paper presents the design of a low-power multi-channel analog front-end(AFE) for bio-potential recording. By using time division multiplexing(TDM), a successive approximation register analog-to-digital converter(SAR ADC) is shared among all 20 channels. A charge-sharing multiplexer(MUX) is proposed to transmit the output signals from the respective channels to the ADC. By separately pre sampling the output of each channel, the sampling time of each channel is greatly extended and additional active buffers are avoided. The AFE is fabricated in a 65-nm CMOS process, and the whole system consumes 28.2 μW under 1 V supply. Each analog acquisition channel consumes 1.25 μW and occupies a chip area of 0.14 mm2. Measurement results show that the AFE achieves an input referred noise of 1.8 μV·rms in a 350 Hz bandwidth and a noise efficiency factor(NEF) of 4.1. The 12-bit SAR ADC achieves an ENOB of 9.8 bit operating at 25 k S/s. The AFE is experimented on real-world applications by measuring human ECG and a clear ECG waveform is captured.展开更多
The healthcare sector involves many steps to ensure efficient care for patients,such as appointment scheduling,consultation plans,online follow-up,and more.However,existing healthcare mechanisms are unable to facilita...The healthcare sector involves many steps to ensure efficient care for patients,such as appointment scheduling,consultation plans,online follow-up,and more.However,existing healthcare mechanisms are unable to facilitate a large number of patients,as these systems are centralized and hence vulnerable to various issues,including single points of failure,performance bottlenecks,and substantial monetary costs.Furthermore,these mechanisms are unable to provide an efficient mechanism for saving data against unauthorized access.To address these issues,this study proposes a blockchain-based authentication mechanism that authenticates all healthcare stakeholders based on their credentials.Furthermore,also utilize the capabilities of the InterPlanetary File System(IPFS)to store the Electronic Health Record(EHR)in a distributed way.This IPFS platform addresses not only the issue of high data storage costs on blockchain but also the issue of a single point of failure in the traditional centralized data storage model.The simulation results demonstrate that our model outperforms the benchmark schemes and provides an efficient mechanism for managing healthcare sector operations.The results show that it takes approximately 3.5 s for the smart contract to authenticate the node and provide it with the decryption key,which is ultimately used to access the data.The simulation results show that our proposed model outperforms existing solutions in terms of execution time and scalability.The execution time of our model smart contract is around 9000 transactions in just 6.5 s,while benchmark schemes require approximately 7 s for the same number of transactions.展开更多
Pediatric type 1 diabetes(T1D)is a lifelong condition requiring meticulous glucose management to prevent acute and chronic complications.Conventional management of diabetic patients does not allow for continuous monit...Pediatric type 1 diabetes(T1D)is a lifelong condition requiring meticulous glucose management to prevent acute and chronic complications.Conventional management of diabetic patients does not allow for continuous monitoring of glucose trends,and can place patients at risk for hypo-and hyperglycemia.Continuous glucose monitors(CGMs)have emerged as a mainstay for pediatric diabetic care and are continuing to advance treatment by providing real-time blood glucose(BG)data,with trend analysis aided by machine learning(ML)algorithms.These predictive analytics serve to prevent against dangerous BG variations in the perioperative environment for fasted children undergoing surgical stress.Integration of CGM data into electronic health records(EHR)is essential,as it establishes a foundation for future technologic interfaces with artificial intelligence(AI).Challenges in perioperative CGM implementation include equitable device access,protection of patient privacy and data accuracy,ensuring institution of standardized protocols,and financing the cumbersome healthcare costs associated with staff training and technology platforms.This paper advocates for implementation of CGM data into the EHR utilizing multiple facets of AI/ML algorithms.展开更多
Gamma-ray imaging systems are powerful tools in radiographic diagnosis.However,the recorded images suffer from degradations such as noise,blurring,and downsampling,consequently failing to meet high-precision diagnosti...Gamma-ray imaging systems are powerful tools in radiographic diagnosis.However,the recorded images suffer from degradations such as noise,blurring,and downsampling,consequently failing to meet high-precision diagnostic requirements.In this paper,we propose a novel single-image super-resolution algorithm to enhance the spatial resolution of gamma-ray imaging systems.A mathematical model of the gamma-ray imaging system is established based on maximum a posteriori estimation.Within the plug-and-play framework,the half-quadratic splitting method is employed to decouple the data fidelit term and the regularization term.An image denoiser using convolutional neural networks is adopted as an implicit image prior,referred to as a deep denoiser prior,eliminating the need to explicitly design a regularization term.Furthermore,the impact of the image boundary condition on reconstruction results is considered,and a method for estimating image boundaries is introduced.The results show that the proposed algorithm can effectively addresses boundary artifacts.By increasing the pixel number of the reconstructed images,the proposed algorithm is capable of recovering more details.Notably,in both simulation and real experiments,the proposed algorithm is demonstrated to achieve subpixel resolution,surpassing the Nyquist sampling limit determined by the camera pixel size.展开更多
Ye Tianshi was a renowned expert in classical formulas during the Qing Dynasty.He created the Light Bitterness and Mild Pungency Method,which is formulated based on the compatibility of“Xing(bitter almond),Kou(Fructu...Ye Tianshi was a renowned expert in classical formulas during the Qing Dynasty.He created the Light Bitterness and Mild Pungency Method,which is formulated based on the compatibility of“Xing(bitter almond),Kou(Fructus amomi rotundus),Ju(tangerine peel),and Jie(platycodon root)”.This method regulates the dispersion and descent of lung Qi to dispel warm-heat pathogens and smooth the Qi movement of the triple energizer.In the treatment of lung system diseases,Ye classified them into two major categories based on etiology and pathogenesis:excess syndrome of nutrient-defense and deficiency syndrome of nutrient-defense.When discussing the treatment of cough caused by phlegm-fluid retention,he frequently referred to Synopsis of the Golden Chamber and attached great importance to summarizing and absorbing the academic thoughts of predecessors.As an accomplished expert in classical formulas,Ye Tianshi followed the academic essence of Xuanyuan and Qi Bo(founders of TCM theory)and respected the principles of Zhang Zhongjing’s classical formulas,integrating these theories in a coherent manner.With his masterful application of classical formulas to achieve remarkable curative effects,Ye’s academic viewpoints on treating lung system diseases still exert a profound influence on the modern clinical diagnosis and treatment of related diseases.展开更多
The field of digital audio forensics aims to detect threats and fraud in audio signals.Contemporary audio forensic techniques use digital signal processing to detect the authenticity of recorded speech,recognize speak...The field of digital audio forensics aims to detect threats and fraud in audio signals.Contemporary audio forensic techniques use digital signal processing to detect the authenticity of recorded speech,recognize speakers,and recognize recording devices.User-generated audio recordings from mobile phones are very helpful in a number of forensic applications.This article proposed a novel method for recognizing recording devices based on recorded audio signals.First,a database of the features of various recording devices was constructed using 32 recording devices(20 mobile phones of different brands and 12 kinds of recording pens)in various environments.Second,the audio features of each recording device,such as the Mel-frequency cepstral coefficients(MFCC),were extracted from the audio signals and used as model inputs.Finally,support vector machines(SVM)with fractional Gaussian kernel were used to recognize the recording devices from their audio features.Experiments demonstrated that the proposed method had a 93.4%accuracy in recognizing recording devices.展开更多
Chinese Storytelling; Gem of theWorld Oral HeritageAccording to historical records, storytelling,or "Shuoshu", had already become a professionsince the Song Dynasty (960-1279). In theprocess of the increasin...Chinese Storytelling; Gem of theWorld Oral HeritageAccording to historical records, storytelling,or "Shuoshu", had already become a professionsince the Song Dynasty (960-1279). In theprocess of the increasing urbanization ever since,the storyteller was regarded as an integral展开更多
Holter is a kind of widely-used clinical instrument to monitor and diagnoseheart diseases.At present,some kinds of Holter record analogous ECG signal di-rectly.But their complicated recording devices lead to their hig...Holter is a kind of widely-used clinical instrument to monitor and diagnoseheart diseases.At present,some kinds of Holter record analogous ECG signal di-rectly.But their complicated recording devices lead to their high price.Other kindsintroduce semiconductor memory.But their limited capacity makes them quite diffi-cult to record 24-hour ECG signal.The 24-hour Holter system based on digital stor-展开更多
This peper proposes a new type of dynamic ECG (Holier) monitoring andrecording system based on technology or computer controlling and high storage capacitydynamic RAM (DRAM). The system realizes the monitoring and rec...This peper proposes a new type of dynamic ECG (Holier) monitoring andrecording system based on technology or computer controlling and high storage capacitydynamic RAM (DRAM). The system realizes the monitoring and recording ECG signalscontinuously up to 24 hours with the double error criterion ECG data compression algorithm or time error and amplitude error[1], adaptive algorithm for detecting andanalysing the oRS complexes[2] and the technology of high storage capacity DRAM. Itsadvantages are high storage Capacity (4MB), low power dissipation (less titan 30mA).展开更多
An advanced method for rapidly computing holograms of large three-dimensional(3D)objects combines backward ray tracing with adaptive resolution wavefront recording plane(WRP)and adaptive angular spectrum propagation.I...An advanced method for rapidly computing holograms of large three-dimensional(3D)objects combines backward ray tracing with adaptive resolution wavefront recording plane(WRP)and adaptive angular spectrum propagation.In the initial phase,a WRP with adjustable resolution and sampling interval based on the object’s size is defined to capture detailed information from large 3D objects.The second phase employs an adaptive angular spectrum method(ASM)to efficiently compute the propagation from the large-sized WRP to the small-sized computer-generated hologram(CGH).The computation process is accelerated using CUDA and OptiX.Optical experiments confirm that the algorithm can generate high-quality holograms with shadow and occlusion effects at a resolution of 1024×1024 in 29 ms.展开更多
The high frequency-very high frequency(HF-VHF)frequency band is of significant importance in astronomical observations,with applications studying various phenomena such as space weather,solar radio emissions,planetary...The high frequency-very high frequency(HF-VHF)frequency band is of significant importance in astronomical observations,with applications studying various phenomena such as space weather,solar radio emissions,planetary eruptions in the solar system,pulsars,transient sources,and reionization of the early universe.This article introduces the HF-VHF frequency band multifunctional radio astronomical terminal system based on a dual-channel high-speed acquisition board with a frequency observation range of 1-250 MHz and a sampling rate of 500 Msps(Mega samples per second).The maximum quantization bit of the system is 14 bits,with a maximum time resolution of 0.1 s and a maximum spectral resolution of 16 kHz.The system combines spectral analysis of solar radio signals and recording of time-domain data of signals interfering with long baselines,and adopts a server-client separation mode to allow remote operation with separate permissions.It is used in the China-Malaysia joint astronomy project,which can carry out single-site observation of solar radio signals as well as interferometric observation of signals from multiple sites.展开更多
The authors used suspension cells of Populus euphratica to isolate protoplast in the present study. Protoplasts were successfully obtained after 4 hours incubation in enzyme solution containing 1 0% cellulase “o...The authors used suspension cells of Populus euphratica to isolate protoplast in the present study. Protoplasts were successfully obtained after 4 hours incubation in enzyme solution containing 1 0% cellulase “onozuka” R\|10, 0\^01% pectolyase Y\|23,0\^15% macerozyme R\|10 and 0\^1% hemicellulase at 25℃. Outward and inward single channels in plasma membrane were observed using cell\|attached recording of patch\|clamp technique. In this study, single channel records showed that more than one species of channel were obtained. These attempts in protoplast isolation and ion channel recording offers the opportunity to characterize cellular mechanisms of salt tolerance in tree species.展开更多
A microelectrode array（MEA） is presented, which is composed of 60 independent electrodes with 59 working ones and one reference one, and they are divided into 30 pairs. Except for the reference electrode, each pair ...A microelectrode array（MEA） is presented, which is composed of 60 independent electrodes with 59 working ones and one reference one, and they are divided into 30 pairs. Except for the reference electrode, each pair consists of one stimulating electrode and one recording electrode. Supported by the peripheral circuits, four electrode states to study the bioelectrical signal of biological tissue or slice cultured in-vitro on the surface of the electrodes can be realized through each pair of electrodes. The four electrode states are stimulation, recording, stimulation and recording simultaneously, and isolation. The state of each pair of working electrodes can be arbitrarily controlled according to actual needs. The MEAs are fabricated in printed circuit board （PCB） technology. The total area of the PCB-based MEA is 49 mm × 49 mm. The impedance measurement of MEA is carried out in 0.9% sodium chloride solution at room temperature by means of 2-point measurements with an Agilent LCR meter, and the test signal for the impedance measurement is sinusoidal （AC voltage 50 mV, sweeping frequency 20 Hz to 10 kHz）. The electrode impedance is between 200 and 3 kΩ while the frequency is between 500 and 1 000 Hz. The electrode impedance magnitude is inversely proportional to the frequency. Experiments of toad sciatic nerve in-vitro stimulation and recording and signal regeneration between isolated toad sciatic nerves are carried out on the PCB-based MEA. The results show that the MEA can be used for bioelectrical signal stimulation, recording, stimulation and recording simultaneously, and isolation of biological tissues or slices in-vitro.展开更多
Marine fish diversity in the Beibu Gulf from 2014 to 2022 was analyzed,using various methods including at-sea fisheries resource surveys,fishing port surveys,underwater survey techniques,and data from literature,books...Marine fish diversity in the Beibu Gulf from 2014 to 2022 was analyzed,using various methods including at-sea fisheries resource surveys,fishing port surveys,underwater survey techniques,and data from literature,books,and databases,from which 1059 fish species across 40 orders,166 families,and 503 genera were identified.Among them,Acanthuriformes displayed the highest diversity,followed by Carangiformes and Perciformes.Notably,eight alien species were found in the Beibu Gulf.The International Union for Conservation of Nature(IUCN)Red List assessment revealed 51threatened species,primarily cartilaginous fish.Taxonomic changes affected 88.70%of species due to classification adjustments,misidentifications,and junior synonymy.This study contributed new data of the gulf,including one additional order,six new families,34 new genera,and 81 new species,emphasizing the dynamic nature of marine ecosystems.Fish diversity in the gulf was relatively lower than the broader South China Sea,attributed to limited habitats and survey methods.Different survey methods,such as gill nets,trap nets,and underwater cameras,yielded varying results.Ocean currents may have transported deep-sea species into the Beibu Gulf,leading to accidental records.Research gaps exist in unexplored areas,warranting further investigation.Therefore,the Beibu Gulf hosts significant marine biodiversity,but taxonomic challenges and undiscovered species require new research and conservation efforts.展开更多
Objective To re-confirm and characterize the biophysical and pharmacological properties of endogenously expressed human acid-sensing ion channel 1a （hASIC1a） current in HEK293 cells with a modified perfusion methods...Objective To re-confirm and characterize the biophysical and pharmacological properties of endogenously expressed human acid-sensing ion channel 1a （hASIC1a） current in HEK293 cells with a modified perfusion methods. Methods With cell floating method, which is separating the cultured cell from coverslip and putting the cell in front of perfusion tubing, whole cell patch clamp technique was used to record hASICla currents evoked by low pH external solution. Results Using cell floating method, the amplitude of hASICla currents activated by pH 5.0 in HEK293 cells is twice as large as that by the conventional method where the cells remain attached to coverslip. The time to reach peak at two different recording conditions is （21±5） ms and （270±25） ms, respectively. Inactivation time constants are （496±23） ms and （2284±120） ms, respectively. The cell floating method significantly increases the amiloride potency of block on hASIC 1 a [IC50 is （3.4± 1.1 ） μmol/L and （2.4± 0.9） μmol/L, respectively]. Both recording methods have similar pH activation ECs0 （6.6±0.6, 6.6±0.7, respectively）. Conclusion ASICs channel activation requires fast exchange of extracellular solution with the different pH values. With cell floating method, the presence of hASIC la current was re-confirmed and the biophysical and pharmacological properties of hASIC la channel in HEK293 cells was precisely characterized. This method could be used to study all ASICs and other ligand-gated channels that require fast extracellular solution exchange.展开更多
基金supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(Nos.2019R1A2C1002221 and RS-2023-00252186)Institute of Information&Communications Technology Planning&Evaluation(IITP)grant funded by the Korea government(MSIT)(Nos.2021-0-00590,RS-2021-II210590Decentralized High Performance Consensus for Large-Scale Blockchains).
文摘Personal video recorders (PVRs) have altered the way users consume television (TV) content by allowing users to record programs and watch them at their convenience, overcoming the constraints of live broadcasting. However, standalone PVRs are limited by their individual storage capacities, restricting the number of programs they can store. While online catch-up TV services such as Hulu and Netflix mitigate this limitation by offering on-demand access to broadcast programs shortly after their initial broadcast, they require substantial storage and network resources, leading to significant infrastructural costs for service providers. To address these challenges, we propose a collaborative TV content recording system that leverages distributed PVRs, combining their storage into a virtual shared pool without additional costs. Our system aims to support all concurrent playback requests without service interruption while ensuring program availability comparable to that of local devices. The main contributions of our proposed system are fourfold. First, by sharing storage and upload bandwidth among PVRs, our system significantly expands the overall recording capacity and enables simultaneous recording of multiple programs without the physical constraints of standalone devices. Second, by utilizing erasure coding efficiently, our system reduces the storage space required for each program, allowing more programs to be recorded compared to traditional replication. Third, we propose an adaptive redundancy scheme to control the degree of redundancy of each program based on its evolving playback demand, ensuring high-quality playback by providing sufficient bandwidth for popular programs. Finally, we introduce a contribution-based incentive policy that encourages PVRs to actively participate by contributing resources, while discouraging excessive consumption of the combined storage pool. Through extensive experiments, we demonstrate the effectiveness of our proposed collaborative TV program recording system in terms of storage efficiency and performance.
基金This work was supported by Research and Development Institute,Nakhon Pathom Rajabhat University,Thailand,under Grant GP_6212.
文摘Bit-Pattemed Magnetic Recording(BPMR)is one of the emerging data storage technologies,which promises an Areal Density(AD)of about 4 Tb/in2.However,a major problem practically encountered in a BPMR system is Inter-Track Interference(ITI)that can deteriorate the overall system performance,especially at high ADs.This paper proposes an iterative ITI cancellation method for an m-head m-track BPMR system,which uses m heads to read m adjacent tracks and decodes them simultaneously.To cancel the ITI,we subtract the weighted readback signals of adjacent tracks,acting as the ITI signals,from the readback signal of the target track,before passing the refined readback signal to a turbo decoder.Then,the decoded data will be employed to reconstruct the ITI signal for the next turbo iteration.Experimental results indicate that the proposed system performs better than the conventional system that uses one head to read one data track.Furthermore,we also find out that the proposed system is more robust to media noise and track misregistration than the conventional system.
文摘In this paper a fault location and recording system based on a computer network is presented. A brief description of the system structure and main features are given. Emphasis is placed on the accurate fault location method for extra high voltage and long distance transmission lines.
基金funded by Ajman University,AU-Funded Research Grant 2023-IRG-ENIT-22.
文摘Cyber-Physical System (CPS) devices are increasing exponentially. Lacking confidentiality creates a vulnerable network. Thus, demanding the overall system with the latest and robust solutions for the defence mechanisms with low computation cost, increased integrity, and surveillance. The proposal of a mechanism that utilizes the features of authenticity measures using the Destination Sequence Distance Vector (DSDV) routing protocol which applies to the multi-WSN (Wireless Sensor Network) of IoT devices in CPS which is developed for the Device-to-Device (D2D) authentication developed from the local-chain and public chain respectively combined with the Software Defined Networking (SDN) control and monitoring system using switches and controllers that will route the packets through the network, identify any false nodes, take preventive measures against them and preventing them for any future problems. Next, the system is powered by Blockchain cryptographic features by utilizing the TrustChain features to create a private, secure, and temper-free ledger of the transactions performed inside the network. Results are achieved in the legitimate devices connecting to the network, transferring their packets to their destination under supervision, reporting whenever a false node is causing hurdles, and recording the transactions for temper-proof records. Evaluation results based on 1000+ transactions illustrate that the proposed mechanism not only outshines most aspects of Cyber-Physical systems but also consumes less computation power with a low latency of 0.1 seconds only.
基金supported by the National Key R&D Program of China under Grant 2018YFA0701400 and 2018YFA0701401.
文摘This paper presents the design of a low-power multi-channel analog front-end(AFE) for bio-potential recording. By using time division multiplexing(TDM), a successive approximation register analog-to-digital converter(SAR ADC) is shared among all 20 channels. A charge-sharing multiplexer(MUX) is proposed to transmit the output signals from the respective channels to the ADC. By separately pre sampling the output of each channel, the sampling time of each channel is greatly extended and additional active buffers are avoided. The AFE is fabricated in a 65-nm CMOS process, and the whole system consumes 28.2 μW under 1 V supply. Each analog acquisition channel consumes 1.25 μW and occupies a chip area of 0.14 mm2. Measurement results show that the AFE achieves an input referred noise of 1.8 μV·rms in a 350 Hz bandwidth and a noise efficiency factor(NEF) of 4.1. The 12-bit SAR ADC achieves an ENOB of 9.8 bit operating at 25 k S/s. The AFE is experimented on real-world applications by measuring human ECG and a clear ECG waveform is captured.
基金supported by the Ongoing Research Funding program(ORF-2025-636),King Saud University,Riyadh,Saudi Arabia.
文摘The healthcare sector involves many steps to ensure efficient care for patients,such as appointment scheduling,consultation plans,online follow-up,and more.However,existing healthcare mechanisms are unable to facilitate a large number of patients,as these systems are centralized and hence vulnerable to various issues,including single points of failure,performance bottlenecks,and substantial monetary costs.Furthermore,these mechanisms are unable to provide an efficient mechanism for saving data against unauthorized access.To address these issues,this study proposes a blockchain-based authentication mechanism that authenticates all healthcare stakeholders based on their credentials.Furthermore,also utilize the capabilities of the InterPlanetary File System(IPFS)to store the Electronic Health Record(EHR)in a distributed way.This IPFS platform addresses not only the issue of high data storage costs on blockchain but also the issue of a single point of failure in the traditional centralized data storage model.The simulation results demonstrate that our model outperforms the benchmark schemes and provides an efficient mechanism for managing healthcare sector operations.The results show that it takes approximately 3.5 s for the smart contract to authenticate the node and provide it with the decryption key,which is ultimately used to access the data.The simulation results show that our proposed model outperforms existing solutions in terms of execution time and scalability.The execution time of our model smart contract is around 9000 transactions in just 6.5 s,while benchmark schemes require approximately 7 s for the same number of transactions.
文摘Pediatric type 1 diabetes(T1D)is a lifelong condition requiring meticulous glucose management to prevent acute and chronic complications.Conventional management of diabetic patients does not allow for continuous monitoring of glucose trends,and can place patients at risk for hypo-and hyperglycemia.Continuous glucose monitors(CGMs)have emerged as a mainstay for pediatric diabetic care and are continuing to advance treatment by providing real-time blood glucose(BG)data,with trend analysis aided by machine learning(ML)algorithms.These predictive analytics serve to prevent against dangerous BG variations in the perioperative environment for fasted children undergoing surgical stress.Integration of CGM data into electronic health records(EHR)is essential,as it establishes a foundation for future technologic interfaces with artificial intelligence(AI).Challenges in perioperative CGM implementation include equitable device access,protection of patient privacy and data accuracy,ensuring institution of standardized protocols,and financing the cumbersome healthcare costs associated with staff training and technology platforms.This paper advocates for implementation of CGM data into the EHR utilizing multiple facets of AI/ML algorithms.
基金supported by the National Natural Science Foundation of China(Grant No.12175183)。
文摘Gamma-ray imaging systems are powerful tools in radiographic diagnosis.However,the recorded images suffer from degradations such as noise,blurring,and downsampling,consequently failing to meet high-precision diagnostic requirements.In this paper,we propose a novel single-image super-resolution algorithm to enhance the spatial resolution of gamma-ray imaging systems.A mathematical model of the gamma-ray imaging system is established based on maximum a posteriori estimation.Within the plug-and-play framework,the half-quadratic splitting method is employed to decouple the data fidelit term and the regularization term.An image denoiser using convolutional neural networks is adopted as an implicit image prior,referred to as a deep denoiser prior,eliminating the need to explicitly design a regularization term.Furthermore,the impact of the image boundary condition on reconstruction results is considered,and a method for estimating image boundaries is introduced.The results show that the proposed algorithm can effectively addresses boundary artifacts.By increasing the pixel number of the reconstructed images,the proposed algorithm is capable of recovering more details.Notably,in both simulation and real experiments,the proposed algorithm is demonstrated to achieve subpixel resolution,surpassing the Nyquist sampling limit determined by the camera pixel size.
文摘Ye Tianshi was a renowned expert in classical formulas during the Qing Dynasty.He created the Light Bitterness and Mild Pungency Method,which is formulated based on the compatibility of“Xing(bitter almond),Kou(Fructus amomi rotundus),Ju(tangerine peel),and Jie(platycodon root)”.This method regulates the dispersion and descent of lung Qi to dispel warm-heat pathogens and smooth the Qi movement of the triple energizer.In the treatment of lung system diseases,Ye classified them into two major categories based on etiology and pathogenesis:excess syndrome of nutrient-defense and deficiency syndrome of nutrient-defense.When discussing the treatment of cough caused by phlegm-fluid retention,he frequently referred to Synopsis of the Golden Chamber and attached great importance to summarizing and absorbing the academic thoughts of predecessors.As an accomplished expert in classical formulas,Ye Tianshi followed the academic essence of Xuanyuan and Qi Bo(founders of TCM theory)and respected the principles of Zhang Zhongjing’s classical formulas,integrating these theories in a coherent manner.With his masterful application of classical formulas to achieve remarkable curative effects,Ye’s academic viewpoints on treating lung system diseases still exert a profound influence on the modern clinical diagnosis and treatment of related diseases.
基金supported by the Jiangsu University Student Training Program[SJCX19_0529]the research fund of Nanjing Institute of Engineering[CXY201931]the National Natural Science Foundation of China(61871213).
文摘The field of digital audio forensics aims to detect threats and fraud in audio signals.Contemporary audio forensic techniques use digital signal processing to detect the authenticity of recorded speech,recognize speakers,and recognize recording devices.User-generated audio recordings from mobile phones are very helpful in a number of forensic applications.This article proposed a novel method for recognizing recording devices based on recorded audio signals.First,a database of the features of various recording devices was constructed using 32 recording devices(20 mobile phones of different brands and 12 kinds of recording pens)in various environments.Second,the audio features of each recording device,such as the Mel-frequency cepstral coefficients(MFCC),were extracted from the audio signals and used as model inputs.Finally,support vector machines(SVM)with fractional Gaussian kernel were used to recognize the recording devices from their audio features.Experiments demonstrated that the proposed method had a 93.4%accuracy in recognizing recording devices.
文摘Chinese Storytelling; Gem of theWorld Oral HeritageAccording to historical records, storytelling,or "Shuoshu", had already become a professionsince the Song Dynasty (960-1279). In theprocess of the increasing urbanization ever since,the storyteller was regarded as an integral
文摘Holter is a kind of widely-used clinical instrument to monitor and diagnoseheart diseases.At present,some kinds of Holter record analogous ECG signal di-rectly.But their complicated recording devices lead to their high price.Other kindsintroduce semiconductor memory.But their limited capacity makes them quite diffi-cult to record 24-hour ECG signal.The 24-hour Holter system based on digital stor-
文摘This peper proposes a new type of dynamic ECG (Holier) monitoring andrecording system based on technology or computer controlling and high storage capacitydynamic RAM (DRAM). The system realizes the monitoring and recording ECG signalscontinuously up to 24 hours with the double error criterion ECG data compression algorithm or time error and amplitude error[1], adaptive algorithm for detecting andanalysing the oRS complexes[2] and the technology of high storage capacity DRAM. Itsadvantages are high storage Capacity (4MB), low power dissipation (less titan 30mA).
基金Project supported by the Special Project of Central Government Guiding Local Science and Technology Development in Beijing 2020(Grant No.Z201100004320006).
文摘An advanced method for rapidly computing holograms of large three-dimensional(3D)objects combines backward ray tracing with adaptive resolution wavefront recording plane(WRP)and adaptive angular spectrum propagation.In the initial phase,a WRP with adjustable resolution and sampling interval based on the object’s size is defined to capture detailed information from large 3D objects.The second phase employs an adaptive angular spectrum method(ASM)to efficiently compute the propagation from the large-sized WRP to the small-sized computer-generated hologram(CGH).The computation process is accelerated using CUDA and OptiX.Optical experiments confirm that the algorithm can generate high-quality holograms with shadow and occlusion effects at a resolution of 1024×1024 in 29 ms.
基金supported by National Natural Science Foundation of China(U2031133)National Key Research and Development Program of China(11941003)+4 种基金Applied Basic Research Program of Yunnan Province(2019FB009)Basic Research Program of Yunnan Province(202301AT070325)Square Kilometer Array(SKA)Project of the Ministry of Science and Technology of China(2020SKA0110202)International Partnership Program of the Chinese Academy of Sciences(114A11KYSB20200001)Kunming Municipal Foreign(International)Cooperation Base Project(GHJD-2021022).
文摘The high frequency-very high frequency(HF-VHF)frequency band is of significant importance in astronomical observations,with applications studying various phenomena such as space weather,solar radio emissions,planetary eruptions in the solar system,pulsars,transient sources,and reionization of the early universe.This article introduces the HF-VHF frequency band multifunctional radio astronomical terminal system based on a dual-channel high-speed acquisition board with a frequency observation range of 1-250 MHz and a sampling rate of 500 Msps(Mega samples per second).The maximum quantization bit of the system is 14 bits,with a maximum time resolution of 0.1 s and a maximum spectral resolution of 16 kHz.The system combines spectral analysis of solar radio signals and recording of time-domain data of signals interfering with long baselines,and adopts a server-client separation mode to allow remote operation with separate permissions.It is used in the China-Malaysia joint astronomy project,which can carry out single-site observation of solar radio signals as well as interferometric observation of signals from multiple sites.
文摘The authors used suspension cells of Populus euphratica to isolate protoplast in the present study. Protoplasts were successfully obtained after 4 hours incubation in enzyme solution containing 1 0% cellulase “onozuka” R\|10, 0\^01% pectolyase Y\|23,0\^15% macerozyme R\|10 and 0\^1% hemicellulase at 25℃. Outward and inward single channels in plasma membrane were observed using cell\|attached recording of patch\|clamp technique. In this study, single channel records showed that more than one species of channel were obtained. These attempts in protoplast isolation and ion channel recording offers the opportunity to characterize cellular mechanisms of salt tolerance in tree species.
基金The National Natural Science Foundation of China(No. 61076118, 90307013, 90707005)the Natural Science Foundation of Jiangsu Province (No. BK2008032)Special Foundation and Open Foundation of the State Key Laboratory of Bioelectronics of Southeast University
文摘A microelectrode array（MEA） is presented, which is composed of 60 independent electrodes with 59 working ones and one reference one, and they are divided into 30 pairs. Except for the reference electrode, each pair consists of one stimulating electrode and one recording electrode. Supported by the peripheral circuits, four electrode states to study the bioelectrical signal of biological tissue or slice cultured in-vitro on the surface of the electrodes can be realized through each pair of electrodes. The four electrode states are stimulation, recording, stimulation and recording simultaneously, and isolation. The state of each pair of working electrodes can be arbitrarily controlled according to actual needs. The MEAs are fabricated in printed circuit board （PCB） technology. The total area of the PCB-based MEA is 49 mm × 49 mm. The impedance measurement of MEA is carried out in 0.9% sodium chloride solution at room temperature by means of 2-point measurements with an Agilent LCR meter, and the test signal for the impedance measurement is sinusoidal （AC voltage 50 mV, sweeping frequency 20 Hz to 10 kHz）. The electrode impedance is between 200 and 3 kΩ while the frequency is between 500 and 1 000 Hz. The electrode impedance magnitude is inversely proportional to the frequency. Experiments of toad sciatic nerve in-vitro stimulation and recording and signal regeneration between isolated toad sciatic nerves are carried out on the PCB-based MEA. The results show that the MEA can be used for bioelectrical signal stimulation, recording, stimulation and recording simultaneously, and isolation of biological tissues or slices in-vitro.
基金Supported by the Regional Innovation Development Joint Fund Project of the National Natural Science Foundation of China(No.U20A2087)the Shiptime Sharing Project of National Natural Science Foundation of China(No.42249911)。
文摘Marine fish diversity in the Beibu Gulf from 2014 to 2022 was analyzed,using various methods including at-sea fisheries resource surveys,fishing port surveys,underwater survey techniques,and data from literature,books,and databases,from which 1059 fish species across 40 orders,166 families,and 503 genera were identified.Among them,Acanthuriformes displayed the highest diversity,followed by Carangiformes and Perciformes.Notably,eight alien species were found in the Beibu Gulf.The International Union for Conservation of Nature(IUCN)Red List assessment revealed 51threatened species,primarily cartilaginous fish.Taxonomic changes affected 88.70%of species due to classification adjustments,misidentifications,and junior synonymy.This study contributed new data of the gulf,including one additional order,six new families,34 new genera,and 81 new species,emphasizing the dynamic nature of marine ecosystems.Fish diversity in the gulf was relatively lower than the broader South China Sea,attributed to limited habitats and survey methods.Different survey methods,such as gill nets,trap nets,and underwater cameras,yielded varying results.Ocean currents may have transported deep-sea species into the Beibu Gulf,leading to accidental records.Research gaps exist in unexplored areas,warranting further investigation.Therefore,the Beibu Gulf hosts significant marine biodiversity,but taxonomic challenges and undiscovered species require new research and conservation efforts.
文摘Objective To re-confirm and characterize the biophysical and pharmacological properties of endogenously expressed human acid-sensing ion channel 1a （hASIC1a） current in HEK293 cells with a modified perfusion methods. Methods With cell floating method, which is separating the cultured cell from coverslip and putting the cell in front of perfusion tubing, whole cell patch clamp technique was used to record hASICla currents evoked by low pH external solution. Results Using cell floating method, the amplitude of hASICla currents activated by pH 5.0 in HEK293 cells is twice as large as that by the conventional method where the cells remain attached to coverslip. The time to reach peak at two different recording conditions is （21±5） ms and （270±25） ms, respectively. Inactivation time constants are （496±23） ms and （2284±120） ms, respectively. The cell floating method significantly increases the amiloride potency of block on hASIC 1 a [IC50 is （3.4± 1.1 ） μmol/L and （2.4± 0.9） μmol/L, respectively]. Both recording methods have similar pH activation ECs0 （6.6±0.6, 6.6±0.7, respectively）. Conclusion ASICs channel activation requires fast exchange of extracellular solution with the different pH values. With cell floating method, the presence of hASIC la current was re-confirmed and the biophysical and pharmacological properties of hASIC la channel in HEK293 cells was precisely characterized. This method could be used to study all ASICs and other ligand-gated channels that require fast extracellular solution exchange.
