Objective: to explore the clinical value of rebeprazole and omeprazole in gastric ulcer. Methods: patients with gastric ulcer were recorded in this experiment. Experiments began in July 2010 and ended in July 2021.A t...Objective: to explore the clinical value of rebeprazole and omeprazole in gastric ulcer. Methods: patients with gastric ulcer were recorded in this experiment. Experiments began in July 2010 and ended in July 2021.A total of 94 patients, equally divided to different groups, were based on the lottery method. Reference group: 47 patients were treated together with omeprazole, clarithromycin, amoxicillin, and colloidal pectin, bismuth. Test group: rebeprazole sodium enteric-coated tablets, clarithromycin, amoxicillin, colloidal pectin and bismuth therapy. Observation index: Improvement of clinical symptoms score of group 2 gastric ulcer patients, improvement of gastrointestinal hormone level, improvement of ulcer area and pain score;and occurrence of adverse reactions. Results: (1) Before treatment, the difference of clinical symptoms was weak, with P-value was 0.05.After treatment, the points of stomach pain, abdominal distension, acid reflux and poor appetite were decreased, and the test group had lower points, and the P-value was less than 0.05. (2) Before the treatment, the distribution of gastrointestinal hormone levels was relatively balanced, with a large P-value ratio of 0.05.After treatment, gastrin level and motility level decreased in each group, and the test group had lower data with a P value less than 0.05. (3) Before treatment, the ulcer area and pain score were similar, with a large P-value ratio of 0.05.After treatment, the ulcer area and pain score in each group showed a downward trend, and the value of the test group was smaller, and the P-value was less than 0.05. (4) In The reference group, the probability of adverse reactions such as gastric spasm, nausea and dizziness was higher than that of the test group, and the P-value was less than 0.05. Conclusion: based on the treatment of gastric ulcer.The improvement of symptom integral and the improvement of gastrointestinal hormone level were more obvious, and the ulcer area was reduced, and the pain was relieved.展开更多
文摘Objective: to explore the clinical value of rebeprazole and omeprazole in gastric ulcer. Methods: patients with gastric ulcer were recorded in this experiment. Experiments began in July 2010 and ended in July 2021.A total of 94 patients, equally divided to different groups, were based on the lottery method. Reference group: 47 patients were treated together with omeprazole, clarithromycin, amoxicillin, and colloidal pectin, bismuth. Test group: rebeprazole sodium enteric-coated tablets, clarithromycin, amoxicillin, colloidal pectin and bismuth therapy. Observation index: Improvement of clinical symptoms score of group 2 gastric ulcer patients, improvement of gastrointestinal hormone level, improvement of ulcer area and pain score;and occurrence of adverse reactions. Results: (1) Before treatment, the difference of clinical symptoms was weak, with P-value was 0.05.After treatment, the points of stomach pain, abdominal distension, acid reflux and poor appetite were decreased, and the test group had lower points, and the P-value was less than 0.05. (2) Before the treatment, the distribution of gastrointestinal hormone levels was relatively balanced, with a large P-value ratio of 0.05.After treatment, gastrin level and motility level decreased in each group, and the test group had lower data with a P value less than 0.05. (3) Before treatment, the ulcer area and pain score were similar, with a large P-value ratio of 0.05.After treatment, the ulcer area and pain score in each group showed a downward trend, and the value of the test group was smaller, and the P-value was less than 0.05. (4) In The reference group, the probability of adverse reactions such as gastric spasm, nausea and dizziness was higher than that of the test group, and the P-value was less than 0.05. Conclusion: based on the treatment of gastric ulcer.The improvement of symptom integral and the improvement of gastrointestinal hormone level were more obvious, and the ulcer area was reduced, and the pain was relieved.
