Background The patient-reported Dimensional Anhedonia Rating Scale(DARS)has been adapted into Chinese,so there is a need to evaluate its measurement properties in a Chinese population.Aims To evaluate the reliability ...Background The patient-reported Dimensional Anhedonia Rating Scale(DARS)has been adapted into Chinese,so there is a need to evaluate its measurement properties in a Chinese population.Aims To evaluate the reliability and validity of the DARS among Chinese individuals with major depressive disorder(MDD)and its treatment sensitivity in a prospective clinical study.Methods Data were from a multicentre,prospective clinical study(NCT03294525),which recruited both patients with MDD,who were followed for 8 weeks,and healthy controls(HCs),assessed at baseline only.The analysis included confirmatory factor analysis,validity and sensitivity to change.Results Patients’mean(standard deviation(SD))age was 34.8(11.0)years,with 68.7%being female.75.2%of patients with MDD had melancholic features,followed by 63.8%with anxious distress.Patients had experienced MDD for a mean(SD)of 9.2(18)months.DARS scores covered the full range of severity with no major floor or ceiling effects.Confirmatory factor analysis showed adequate fit statistics(comparative fit index 0.976,goodness-of-fit index 0.935 and root mean square error of approximation 0.055).Convergent validity with anhedonia-related measures was confirmed.While the correlation between the DARS and the Hamilton Depression Rating Scale was not strong(r=0.31,baseline),the DARS was found to differentiate between levels of depression.Greater improvements in DARS scores were seen with the Hamilton Rating Scale for Depression responder group(effect size 1.16)compared with the non-responder group(effect size 0.46).Conclusions This study comprehensively evaluated the measurement properties of the DARS using a Chinese population with MDD.Overall,the Chinese version of DARS demonstrates good psychometric properties and has been found to be responsive to change during antidepressant treatment.The DARS is a suitable scale for assessing patient-reported anhedonia in future clinical trials.展开更多
ESG(Environmental,Social,and Governance)performance has emerged as a central metric in assessing corporate sustainability.Utilizing ESG rating data for A-share listed companies on the Shanghai Stock Exchange spanning ...ESG(Environmental,Social,and Governance)performance has emerged as a central metric in assessing corporate sustainability.Utilizing ESG rating data for A-share listed companies on the Shanghai Stock Exchange spanning from 2019 to 2022,coupled with measures of corporate transformation and upgrading,this study introduces green innovation as a mediating variable to dissect the impact of ESG ratings on corporate transformation and upgrading.The key findings of this research are as follows:(1)ESG ratings positively influence corporate transformation and upgrading,a conclusion that retains robustness after a comprehensive series of tests and discussions on endogeneity.(2)Mechanism analysis reveals that ESG ratings foster corporate transformation and upgrading by enhancing corporate green innovation.(3)In comparison with other industries,the influence of ESG ratings on corporate transformation and upgrading is notably more pronounced among heavily polluting industries among listed companies in China.Additionally,ESG ratings exhibit a more significant promotional effect on non-state-owned enterprises compared to state-owned enterprises.Larger enterprises play a more substantial role in transformation and upgrading than small and medium-sized enterprises.The promotional effect of ESG ratings is more evident in enterprises with poor information disclosure quality.Furthermore,as media attention increases,so does the impact of ESG ratings on corporate transformation.This study offers valuable policy insights from the ESG rating perspective,aiming to propel corporate transformation and upgrading,thereby contributing to economic high-quality and sustainable development.展开更多
With increasing density and heterogeneity in unlicensed wireless networks,traditional MAC protocols,such as Carrier Sense Multiple Access with Collision Avoidance(CSMA/CA)in Wi-Fi networks,are experiencing performance...With increasing density and heterogeneity in unlicensed wireless networks,traditional MAC protocols,such as Carrier Sense Multiple Access with Collision Avoidance(CSMA/CA)in Wi-Fi networks,are experiencing performance degradation.This is manifested in increased collisions and extended backoff times,leading to diminished spectrum efficiency and protocol coordination.Addressing these issues,this paper proposes a deep-learning-based MAC paradigm,dubbed DL-MAC,which leverages spectrum data readily available from energy detection modules in wireless devices to achieve the MAC functionalities of channel access,rate adaptation,and channel switch.First,we utilize DL-MAC to realize a joint design of channel access and rate adaptation.Subsequently,we integrate the capability of channel switching into DL-MAC,enhancing its functionality from single-channel to multi-channel operations.Specifically,the DL-MAC protocol incorporates a Deep Neural Network(DNN)for channel selection and a Recurrent Neural Network(RNN)for the joint design of channel access and rate adaptation.We conducted real-world data collection within the 2.4 GHz frequency band to validate the effectiveness of DL-MAC.Experimental results demonstrate that DL-MAC exhibits significantly superior performance compared to traditional algorithms in both single and multi-channel environments,and also outperforms single-function designs.Additionally,the performance of DL-MAC remains robust,unaffected by channel switch overheads within the evaluation range.展开更多
The acuurate prediction of the time-dependent mechanical behavior and deformation mechanisms of second-phase reinforced alloys under size effects is critical for the development of high-strength ductile metals and all...The acuurate prediction of the time-dependent mechanical behavior and deformation mechanisms of second-phase reinforced alloys under size effects is critical for the development of high-strength ductile metals and alloys for dynamic applications.However,solving their responses using high-fidelity numerical methods is computationally expensive and,in many cases,impractical.To address this issue,a dual-scale incremental variational formulation is proposed that incorporates the influence of plastic gradients on plastic evolution characteristics,integrating a strain-rate-dependent strain gradient plasticity model and including plastic gradients in the inelastic dissipation potential.Subsequently,two minimization problems based on the energy dissipation mechanisms of strain gradient plasticity,corresponding to the macroscopic and microscopic structures,are solved,leading to the development of a homogenization-based dual-scale solution algorithm.Finally,the effectiveness of the variational model and tangent algorithm is validated through a series of numerical simulations.The contributions of this work are as follows:first,it advances the theory of self-consistent computational homogenization modeling based on the energy dissipation mechanisms of plastic strain rates and their gradients,along with the development of a rigorous multi-level finite element method(FE2)solution procedure;second,the proposed algorithm provides an efficient and accurate method for evaluating the time-dependent mechanical behavior of second-phase reinforced alloys under strain gradient effects,exploring how these effects vary with the strain rate,and investigating their potential interactions.展开更多
Concentrated solar thermal power generation has been experimentally tested in advanced countries for a period of time.This paper demonstrates how this technology can be improved by using water molecules as a medium to...Concentrated solar thermal power generation has been experimentally tested in advanced countries for a period of time.This paper demonstrates how this technology can be improved by using water molecules as a medium to drive traditional generator sets for energy conversion,thereby simultaneously improving the energy conversion rate.Additionally,a novel contribution is made by incorporating a magic number 4 to enhance the focusing efficiency of Fresnel lenses,which drives improvements in power generation output and QE(Quantum Efficiency).展开更多
提出基于短语参数学习的主题模型TMPP(Topic Model based on Phrase Parameter)对在线评论中被评价实体的aspect和与之对应的rating进行抽取.TMPP具有三个特点:1)评论用"短语袋"表示;2)将标准的LDA中表示文档-主题的参数扩展...提出基于短语参数学习的主题模型TMPP(Topic Model based on Phrase Parameter)对在线评论中被评价实体的aspect和与之对应的rating进行抽取.TMPP具有三个特点:1)评论用"短语袋"表示;2)将标准的LDA中表示文档-主题的参数扩展为(aspect,rating)集;3)融合了先验知识.介绍了TMPP模型参数的物理含义、模型的生成过程以及先验知识的获取和表示方法;阐述了在TMPP模型中引入方面集聚类使用先验知识的原因与好处、TMPP模型提取(方面,等级)对形成(aspect,rating)摘要的原理.以真实的在线产品评论数据集为实验对象,在实验过程中引入先验知识的方面识别分析和等级预测精度分析,列出了五类产品相关方面和对立的情感词的实验结果.通过与已有的基线方法比较,实验表明若评论集中每篇评论有一个总体等级,TMPP能产生高质量的(aspect,rating)摘要.展开更多
MEMS gyroscope is a new inertial navigation sensor,which can measure the input angular rate of sensitive axis using Coriolis effect.Compared to the conventional gyroscope,it owns many unique advantages.A novel structu...MEMS gyroscope is a new inertial navigation sensor,which can measure the input angular rate of sensitive axis using Coriolis effect.Compared to the conventional gyroscope,it owns many unique advantages.A novel structure of vibrating ring gyroscope is proposed and the finite element model of the oscillator is established based on MEMS technology.Through the modal analysis,the natural frequency and mode shapes of the oscillator are obtained.By analyzing the effects of the structural parameters on the mode shapes and frequency of the harmonic oscillator,the optimal design parameters are got.The frequency difference between the operating mode and the other modes is greater than 1kHz after optimization,which can avoid the frequency coupling of the operating mode and other vibrating modes of the oscillator.The simulation results show that the performance parameters of the ring structure meet the design requirements and have obvious advantages.展开更多
[Objective] This paper aimed to improve the detection rate of probe EUB338 for eubacteria.[Methods] Sixteen strains were used as materials for the experiment and analyzed through fluorescence in situ hybridization.[Re...[Objective] This paper aimed to improve the detection rate of probe EUB338 for eubacteria.[Methods] Sixteen strains were used as materials for the experiment and analyzed through fluorescence in situ hybridization.[Result] The average detection rate of probe EUB338 was 63.9%,which can be increased to 71.3% through modified FISH.[Conclusion] This research was able to provide scientific basis for the detection of eubacteria in soil from the perspective of molecular biology.展开更多
Fine-grained nuclear graphite is a key material in high-temperature gas-cooled reactors(HTGRs).During air ingress accidents,core graphite components undergo severe oxidation,threatening structural integrity.Therefore,...Fine-grained nuclear graphite is a key material in high-temperature gas-cooled reactors(HTGRs).During air ingress accidents,core graphite components undergo severe oxidation,threatening structural integrity.Therefore,understanding the oxidation behavior of nuclear graphite is essential for reactor safety.The influence of oxidation involves multiple factors,including temperature,sample size,oxidant,impurities,filler type and size,etc.The size of the filler particles plays a crucial role in this study.Five ultrafine-and superfine-grained nuclear graphite samples(5.9-34.4μm)are manufactured using identical raw materials and manufacturing processes.Isothermal oxidation tests conducted at 650℃-750℃ are used to study the oxidation behavior.Additionally,comprehensive characterization is performed to analyze the crystal structure,surface morphology,and nanoscale to microscale pore structure of the samples.Results indicate that oxidation behavior cannot be predicted solely based on filler grain size.Reactive site concentration,characterized by active surface area,dominates the chemical reaction kinetics,whereas pore tortuosity,quantified by the structural parameterΨ,plays a key role in regulating oxidant diffusion.These findings clarify the dual role of microstructure in oxidation mechanisms and establish a theoretical and experimental basis for the design of high-performance nuclear graphite capable of long-term service in high-temperature gas-cooled reactors.展开更多
In the complex architecture of global value-chain(GVC)trade,firms’technological content increasingly reflects external knowledge flows.This study examines how inter-regional technological complementarity shapes firms...In the complex architecture of global value-chain(GVC)trade,firms’technological content increasingly reflects external knowledge flows.This study examines how inter-regional technological complementarity shapes firms’GVC advancement,measured by the domestic value-added rate(DVAR)in exports.Using integrated Chinese microdata(2000-2014),we find this complementarity significantly boosts export DVAR,explaining about one-quarter of its observed growth.Two mechanisms drive this effect:increased use of domestic intermediates and gains in firm productivity.The benefits are especially large for firms with lower human capital and for those in accessible,innovation-peripheral regions,helping narrow productivity gaps across firms and space.Affected firms also exhibit broader export scopes,higher product quality,more diversified destinations,and greater markups-firm-level evidence of GVC upgrading.These findings highlight how external technological linkages drive upgrading and underscore the importance of fostering inter-regional synergies for balanced development.展开更多
Effective treatment methods for stroke,a common cerebrovascular disease with a high mortality rate,are still being sought.Exosome therapy,a form of acellular therapy,has demonstrated promising efficacy in various dise...Effective treatment methods for stroke,a common cerebrovascular disease with a high mortality rate,are still being sought.Exosome therapy,a form of acellular therapy,has demonstrated promising efficacy in various diseases in animal models;however,there is currently insufficient evidence to guide the clinical application of exosome in patients with stroke.This article reviews the progress of exosome applications in stroke treatment.It aims to elucidate the significant potential value of exosomes in stroke therapy and provide a reference for their clinical translation.At present,many studies on exosome-based therapies for stroke are actively underway.Regarding preclinical research,exosomes,as bioactive substances with diverse sources,currently favor stem cells as their origin.Due to their high plasticity,exosomes can be effectively modified through various physical,chemical,and genetic engineering methods to enhance their efficacy.In animal models of stroke,exosome therapy can reduce neuroinflammatory responses,alleviate oxidative stress damage,and inhibit programmed cell death.Additionally,exosomes can promote angiogenesis,repair and regenerate damaged white matter fiber bundles,and facilitate the migration and differentiation of neural stem cells,aiding the repair process.We also summarize new directions for the application of exosomes,specifically the exosome intervention through the ventricular-meningeal lymphatic system.The review findings suggest that the treatment paradigm for stroke is poised for transformation.展开更多
A high-sensitivity,low-noise single photon avalanche diode(SPAD)detector was presented based on a 180 nm BCD process.The proposed device utilizes a p-implant layer/high-voltage n-well(HVNW)junction to form a deep aval...A high-sensitivity,low-noise single photon avalanche diode(SPAD)detector was presented based on a 180 nm BCD process.The proposed device utilizes a p-implant layer/high-voltage n-well(HVNW)junction to form a deep avalanche multiplication region for near-infrared(NIR)sensitivity enhancement.By optimizing the device size and electric field of the guard ring,the fill factor(FF)is significantly improved,further increasing photon detection efficiency(PDE).To solve the dark noise caused by the increasing active diameter,a field polysilicon gate structure connected to the p+anode was investigated,effectively suppressing dark count noise by 76.6%.It is experimentally shown that when the active diameter increases from 5 to 10μm,the FF is significantly improved from 20.7%to 39.1%,and thus the peak PDE also rises from 13.3%to 25.8%.At an excess bias voltage of 5 V,a NIR photon detection probability(PDP)of 6.8%at 905 nm,a dark count rate(DCR)of 2.12 cps/μm^(2),an afterpulsing probability(AP)of 1.2%,and a timing jitter of 216 ps are achieved,demonstrating excellent single photon detection performance.展开更多
The Autism Spectrum Rating Scale(ASRS) and the Social Responsiveness Scale(SRS) have been widely used for screening autism spectrum disorder(ASD) in the general population during epidemiological studies, but studies o...The Autism Spectrum Rating Scale(ASRS) and the Social Responsiveness Scale(SRS) have been widely used for screening autism spectrum disorder(ASD) in the general population during epidemiological studies, but studies of individuals with intellectual disability(ID) are quite limited. Therefore, we recruited the parents/caregivers of 204 ASD cases, 71 ID cases aged 6–18 years from special education schools, and 402 typically developing(TD) children in the same age span from a communitybased population to complete the ASRS and SRS. The results showed that the ID group scored significantly lower on total and subscale scores than the ASD group on both scales(P \ 0.05) but higher than TD children(P \ 0.05).Receiver operating characteristic analyses demonstrated a similar fair performance in discriminating ASD from ID with the ASRS(area under the curve(AUC) = 0.709,sensitivity = 77.0%, specificity = 52.1%, positive predictive value(PPV) = 82.2%) and the SRS(AUC = 0.742,sensitivity = 59.8%, specificity = 77.5%, PPV = 88.4%).The results showed that individuals with ID had clear autistic traits and discriminating ASD from ID cases was quite challenging, while assessment tools such as ASRS and SRS, help to some degree.展开更多
OBJECTIVE: To evaluate the effects of Guasha therapy on the rating of perceived exertion(RPE) scale score, and heart rate variability(HRV).METHODS: A randomized controlled trial of Guasha(skin scraping) was compared w...OBJECTIVE: To evaluate the effects of Guasha therapy on the rating of perceived exertion(RPE) scale score, and heart rate variability(HRV).METHODS: A randomized controlled trial of Guasha(skin scraping) was compared with a sham scraping group and control group. Sixteen sessions within an 8-week period were completed. Sixty-five male weightlifters who had undergone normal weightlifting training for a mean of 5 years before study commencement were recruited. The RPEscale score of "snatch", "clean and jerk" maneuvers(85% of one-repetition maximum), and HRV were measured before and after the intervention.RESULTS: The RPE scale score for snatch, clean and jerk were reduced significantly after intervention in the Guasha group and sham group. However, there was a significant difference in the low frequency(LF) domain and LF/high frequency(HF) ratio(P <0.05): the LF domain decreased, and the LF/HF ratio decreased.CONCLUSION: Guasha could be used to reduce the RPE scale score, and increase the response to HRV.Guasha could be considered as an alternative to some types of recovery from sports training.展开更多
Rock mass classification systems are the very important part for underground projects and rock mass rating(RMR) is one of the most commonly applied classification systems in numerous civil and mining projects. The typ...Rock mass classification systems are the very important part for underground projects and rock mass rating(RMR) is one of the most commonly applied classification systems in numerous civil and mining projects. The type of rock mass consisting of an interbedding of strong and weak layers poses difficulties and uncertainties for determining the RMR. For this, the present paper uses the concept of rock bolt supporting factor(RSF) for modification of RMR system to be used in such rock mass types. The proposed method also demonstrates the importance of rock bolting practice in such rock masses. The geological parameters of the Shemshak Formation of the Alborz Tunnel in Iran are used as case examples for development of the theoretical approach.展开更多
The reported prevalence of autism spectrum disorder（ASD） has been increasing rapidly in many parts of the world. However, data on its prevalence in China are largely missing. Here, we assessed the suitability of the...The reported prevalence of autism spectrum disorder（ASD） has been increasing rapidly in many parts of the world. However, data on its prevalence in China are largely missing. Here, we assessed the suitability of the modi？ed Chinese version of a newly-developed ASD screening tool, the Modi？ed Chinese Autism Spectrum Rating Scales（MC-ASRS） in screening for ASD in Chi nese children aged 6–12 years, through comparison with the Social Responsiveness Scale（SRS） that has been widely used for ASD screening. We recruited the par ents/caregivers of 1588 typically-developing children and190 children with ASD aged 6–12 years to complete the MC-ASRS and SRS, and evaluated the validity of both scales in discriminating children with ASD from those developing typically. The results showed that MC-ASRSperformed as well as SRS in sensitivity, speci？city, and area-under-the-curve（both [0.95） in receiver operating characteristic analysis, with a fair false-negative rate.These results suggest that MC-ASRS is a promising tool for screening for children with ASD in the general Chinese population.展开更多
Comparisons of red ratings (RR) with Fe_d, Fe_d/Fet, clay content, andmagnetic susceptibility (x) of two loess-paleosol sequences at Luochuan and Lingtai on China's LoessPlateau were conducted to study the possibl...Comparisons of red ratings (RR) with Fe_d, Fe_d/Fet, clay content, andmagnetic susceptibility (x) of two loess-paleosol sequences at Luochuan and Lingtai on China's LoessPlateau were conducted to study the possible relationship between RR and pedogenic degrees of thetwo loess-paleosol sequences, and to discuss whether the RR could become new paleo-climaticindicators. Results showed that the RR of the two loess-paleosol sequences had positive, highlysignificant (P < 0.01) correlations with: 1) citrate-bicarbonate-dithionite (CBD) extracted iron(Fe_d), 2) ratios of CBD extracted iron to total iron (Fe_d/Fet), 3) clay (< 2 mum), and 4) magneticsusceptibility (x). This suggested that the RR of these loess-paleosol sequences could indicatedegreesof loess weathering and pedogenesis and were potential paleo-climatic proxies. The strongcorrelations of RR to Fe_d and x also implied that during pedogenic processes, pedogenic hematite inloess and paleosols were closely related to the amount of total secondary iron oxides and pedogenicferrimagnetic minerals (predominantly maghemite).展开更多
In order to design the relief system size of di-tert-butyl peroxide(DTBP) storage tanks,the runaway re-action of DTBP was simulated by accelerating rate calorimeter(ARC).The results indicated that under adiabatic cond...In order to design the relief system size of di-tert-butyl peroxide(DTBP) storage tanks,the runaway re-action of DTBP was simulated by accelerating rate calorimeter(ARC).The results indicated that under adiabatic conditions the initial exothermic temperature was 102.6 ℃,the maximum self-heating rate was 3.095×107 ℃·min-1,the maximum self-heating temperature was 375.9 ℃,and the pressure produced by unit mass was 4.512 MPa·g-1.Judged by ARC test,the emergency relief system for DTBP was a hybrid system.Based on Design Institute for Emergency Relief System(DIERS) method,the releasing mass flow rate W was determined by Leung methods,and the mass velocity G was calculated by two modified Omega methods.The two relief sizes calculated by monograph Omega method and arithmetic Omega method are close,with only 0.63% relative error.The monograph Omega method is more convenient to apply.展开更多
BACKGROUND Autism is the most common clinical developmental disorder in children.The childhood autism rating scale(CARS)and autistic autism behavior checklist(ABC)are the most commonly used assessment scales for diagn...BACKGROUND Autism is the most common clinical developmental disorder in children.The childhood autism rating scale(CARS)and autistic autism behavior checklist(ABC)are the most commonly used assessment scales for diagnosing autism.However,the diagnostic validations and the corresponding cutoffs for CARS and ABC in individuals with suspected autism spectrum disorder(ASD)remain unclear.Furthermore,for suspected ASD in China,it remains unclear whether CARS is a better diagnostic tool than ABC.Also unclear is whether the current cutoff points for ABC and CARS are suitable for the accurate diagnosis of ASD.AIM To investigate the diagnostic validity of CARS and ABC based on a large Chinese sample.METHODS A total of 591 outpatient children from the ASD Unit at Beijing Children’s Hospital between June and November 2019 were identified.First,the Clancy autism behavior scale(CABS)was used to screen out suspected autism from these children.Then,each suspected ASD was evaluated by CARS and ABC.Receiver operating characteristic(ROC)curve analysis was used to compare diagnostic validations.We also calculated the area under the curve(AUC)for both CARS and ABC.RESULTS We found that the Cronbach alpha coefficients of CARS and ABC were 0.772 and 0.426,respectively.Therefore,the reliability of the CARS was higher than that of the ABC.In addition,we found that the correlation between CARS and CABS was 0.732.Next,we performed ROC curve analysis for CARS and ABC,which yielded AUC values of 0.846 and 0.768,respectively.The cutoff value,which is associated with the maximum Youden index,is usually applied as a decision threshold.We found that the cutoff values of CARS and ABC were 34 and 67,respectively.CONCLUSION This result indicated that CARS is superior to ABC in the Chinese population with suspected ASD.展开更多
基金supported by the National Natural Science Foundation of China(No.82371530,82171529)the Capital Health Development Special Research Project(2022-1-4111)the National Key Technology R and D Program(No.2015BAI13B01).
文摘Background The patient-reported Dimensional Anhedonia Rating Scale(DARS)has been adapted into Chinese,so there is a need to evaluate its measurement properties in a Chinese population.Aims To evaluate the reliability and validity of the DARS among Chinese individuals with major depressive disorder(MDD)and its treatment sensitivity in a prospective clinical study.Methods Data were from a multicentre,prospective clinical study(NCT03294525),which recruited both patients with MDD,who were followed for 8 weeks,and healthy controls(HCs),assessed at baseline only.The analysis included confirmatory factor analysis,validity and sensitivity to change.Results Patients’mean(standard deviation(SD))age was 34.8(11.0)years,with 68.7%being female.75.2%of patients with MDD had melancholic features,followed by 63.8%with anxious distress.Patients had experienced MDD for a mean(SD)of 9.2(18)months.DARS scores covered the full range of severity with no major floor or ceiling effects.Confirmatory factor analysis showed adequate fit statistics(comparative fit index 0.976,goodness-of-fit index 0.935 and root mean square error of approximation 0.055).Convergent validity with anhedonia-related measures was confirmed.While the correlation between the DARS and the Hamilton Depression Rating Scale was not strong(r=0.31,baseline),the DARS was found to differentiate between levels of depression.Greater improvements in DARS scores were seen with the Hamilton Rating Scale for Depression responder group(effect size 1.16)compared with the non-responder group(effect size 0.46).Conclusions This study comprehensively evaluated the measurement properties of the DARS using a Chinese population with MDD.Overall,the Chinese version of DARS demonstrates good psychometric properties and has been found to be responsive to change during antidepressant treatment.The DARS is a suitable scale for assessing patient-reported anhedonia in future clinical trials.
文摘ESG(Environmental,Social,and Governance)performance has emerged as a central metric in assessing corporate sustainability.Utilizing ESG rating data for A-share listed companies on the Shanghai Stock Exchange spanning from 2019 to 2022,coupled with measures of corporate transformation and upgrading,this study introduces green innovation as a mediating variable to dissect the impact of ESG ratings on corporate transformation and upgrading.The key findings of this research are as follows:(1)ESG ratings positively influence corporate transformation and upgrading,a conclusion that retains robustness after a comprehensive series of tests and discussions on endogeneity.(2)Mechanism analysis reveals that ESG ratings foster corporate transformation and upgrading by enhancing corporate green innovation.(3)In comparison with other industries,the influence of ESG ratings on corporate transformation and upgrading is notably more pronounced among heavily polluting industries among listed companies in China.Additionally,ESG ratings exhibit a more significant promotional effect on non-state-owned enterprises compared to state-owned enterprises.Larger enterprises play a more substantial role in transformation and upgrading than small and medium-sized enterprises.The promotional effect of ESG ratings is more evident in enterprises with poor information disclosure quality.Furthermore,as media attention increases,so does the impact of ESG ratings on corporate transformation.This study offers valuable policy insights from the ESG rating perspective,aiming to propel corporate transformation and upgrading,thereby contributing to economic high-quality and sustainable development.
基金supported in part by the National Key R&D Program of China under Grant 2021YFB1714100in part by the Shenzhen Science and Technology Program,China,under Grant JCYJ20220531101015033.
文摘With increasing density and heterogeneity in unlicensed wireless networks,traditional MAC protocols,such as Carrier Sense Multiple Access with Collision Avoidance(CSMA/CA)in Wi-Fi networks,are experiencing performance degradation.This is manifested in increased collisions and extended backoff times,leading to diminished spectrum efficiency and protocol coordination.Addressing these issues,this paper proposes a deep-learning-based MAC paradigm,dubbed DL-MAC,which leverages spectrum data readily available from energy detection modules in wireless devices to achieve the MAC functionalities of channel access,rate adaptation,and channel switch.First,we utilize DL-MAC to realize a joint design of channel access and rate adaptation.Subsequently,we integrate the capability of channel switching into DL-MAC,enhancing its functionality from single-channel to multi-channel operations.Specifically,the DL-MAC protocol incorporates a Deep Neural Network(DNN)for channel selection and a Recurrent Neural Network(RNN)for the joint design of channel access and rate adaptation.We conducted real-world data collection within the 2.4 GHz frequency band to validate the effectiveness of DL-MAC.Experimental results demonstrate that DL-MAC exhibits significantly superior performance compared to traditional algorithms in both single and multi-channel environments,and also outperforms single-function designs.Additionally,the performance of DL-MAC remains robust,unaffected by channel switch overheads within the evaluation range.
基金Project supported by the National Natural Science Foundation of China(Nos.11922206,11702089,12272132)the Postgraduate Scientific Research Innovation Project of Hunan Province(No.CX20240388)。
文摘The acuurate prediction of the time-dependent mechanical behavior and deformation mechanisms of second-phase reinforced alloys under size effects is critical for the development of high-strength ductile metals and alloys for dynamic applications.However,solving their responses using high-fidelity numerical methods is computationally expensive and,in many cases,impractical.To address this issue,a dual-scale incremental variational formulation is proposed that incorporates the influence of plastic gradients on plastic evolution characteristics,integrating a strain-rate-dependent strain gradient plasticity model and including plastic gradients in the inelastic dissipation potential.Subsequently,two minimization problems based on the energy dissipation mechanisms of strain gradient plasticity,corresponding to the macroscopic and microscopic structures,are solved,leading to the development of a homogenization-based dual-scale solution algorithm.Finally,the effectiveness of the variational model and tangent algorithm is validated through a series of numerical simulations.The contributions of this work are as follows:first,it advances the theory of self-consistent computational homogenization modeling based on the energy dissipation mechanisms of plastic strain rates and their gradients,along with the development of a rigorous multi-level finite element method(FE2)solution procedure;second,the proposed algorithm provides an efficient and accurate method for evaluating the time-dependent mechanical behavior of second-phase reinforced alloys under strain gradient effects,exploring how these effects vary with the strain rate,and investigating their potential interactions.
文摘Concentrated solar thermal power generation has been experimentally tested in advanced countries for a period of time.This paper demonstrates how this technology can be improved by using water molecules as a medium to drive traditional generator sets for energy conversion,thereby simultaneously improving the energy conversion rate.Additionally,a novel contribution is made by incorporating a magic number 4 to enhance the focusing efficiency of Fresnel lenses,which drives improvements in power generation output and QE(Quantum Efficiency).
文摘提出基于短语参数学习的主题模型TMPP(Topic Model based on Phrase Parameter)对在线评论中被评价实体的aspect和与之对应的rating进行抽取.TMPP具有三个特点:1)评论用"短语袋"表示;2)将标准的LDA中表示文档-主题的参数扩展为(aspect,rating)集;3)融合了先验知识.介绍了TMPP模型参数的物理含义、模型的生成过程以及先验知识的获取和表示方法;阐述了在TMPP模型中引入方面集聚类使用先验知识的原因与好处、TMPP模型提取(方面,等级)对形成(aspect,rating)摘要的原理.以真实的在线产品评论数据集为实验对象,在实验过程中引入先验知识的方面识别分析和等级预测精度分析,列出了五类产品相关方面和对立的情感词的实验结果.通过与已有的基线方法比较,实验表明若评论集中每篇评论有一个总体等级,TMPP能产生高质量的(aspect,rating)摘要.
文摘MEMS gyroscope is a new inertial navigation sensor,which can measure the input angular rate of sensitive axis using Coriolis effect.Compared to the conventional gyroscope,it owns many unique advantages.A novel structure of vibrating ring gyroscope is proposed and the finite element model of the oscillator is established based on MEMS technology.Through the modal analysis,the natural frequency and mode shapes of the oscillator are obtained.By analyzing the effects of the structural parameters on the mode shapes and frequency of the harmonic oscillator,the optimal design parameters are got.The frequency difference between the operating mode and the other modes is greater than 1kHz after optimization,which can avoid the frequency coupling of the operating mode and other vibrating modes of the oscillator.The simulation results show that the performance parameters of the ring structure meet the design requirements and have obvious advantages.
基金Supported by the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministrythe National Natural Science Foundation of China(No.21047001)the Standards Foundation of Shanghai City(No.10DZ0503900)~~
文摘[Objective] This paper aimed to improve the detection rate of probe EUB338 for eubacteria.[Methods] Sixteen strains were used as materials for the experiment and analyzed through fluorescence in situ hybridization.[Result] The average detection rate of probe EUB338 was 63.9%,which can be increased to 71.3% through modified FISH.[Conclusion] This research was able to provide scientific basis for the detection of eubacteria in soil from the perspective of molecular biology.
基金supported by the National Key Research and Development Program of China(2024YFA1612900)the National Natural Science Foundation of China(Grant No.52103365 and No.12375270)the Guangdong Innovative and Entrepreneurial Research Team Program,China(Grant No.2021ZT09L227).
文摘Fine-grained nuclear graphite is a key material in high-temperature gas-cooled reactors(HTGRs).During air ingress accidents,core graphite components undergo severe oxidation,threatening structural integrity.Therefore,understanding the oxidation behavior of nuclear graphite is essential for reactor safety.The influence of oxidation involves multiple factors,including temperature,sample size,oxidant,impurities,filler type and size,etc.The size of the filler particles plays a crucial role in this study.Five ultrafine-and superfine-grained nuclear graphite samples(5.9-34.4μm)are manufactured using identical raw materials and manufacturing processes.Isothermal oxidation tests conducted at 650℃-750℃ are used to study the oxidation behavior.Additionally,comprehensive characterization is performed to analyze the crystal structure,surface morphology,and nanoscale to microscale pore structure of the samples.Results indicate that oxidation behavior cannot be predicted solely based on filler grain size.Reactive site concentration,characterized by active surface area,dominates the chemical reaction kinetics,whereas pore tortuosity,quantified by the structural parameterΨ,plays a key role in regulating oxidant diffusion.These findings clarify the dual role of microstructure in oxidation mechanisms and establish a theoretical and experimental basis for the design of high-performance nuclear graphite capable of long-term service in high-temperature gas-cooled reactors.
基金supported by the following grants:National Social Science Fund of China(NSSFC)(Major Project)“Research on the Mechanism and Breakthrough Path for Achieving Key Core Technologies through the Coupling of Innovation Chains and Industrial Chains”(Grant No.22&ZD093)Key Research Institute of Humanities and Social Sciences,Ministry of Education“Research on Innovation Development Theory Based on Chinese Practice”(Grant No.23CEDRZ03).
文摘In the complex architecture of global value-chain(GVC)trade,firms’technological content increasingly reflects external knowledge flows.This study examines how inter-regional technological complementarity shapes firms’GVC advancement,measured by the domestic value-added rate(DVAR)in exports.Using integrated Chinese microdata(2000-2014),we find this complementarity significantly boosts export DVAR,explaining about one-quarter of its observed growth.Two mechanisms drive this effect:increased use of domestic intermediates and gains in firm productivity.The benefits are especially large for firms with lower human capital and for those in accessible,innovation-peripheral regions,helping narrow productivity gaps across firms and space.Affected firms also exhibit broader export scopes,higher product quality,more diversified destinations,and greater markups-firm-level evidence of GVC upgrading.These findings highlight how external technological linkages drive upgrading and underscore the importance of fostering inter-regional synergies for balanced development.
基金supported by the Natural Science Foundation of Chongqing,No.CSTB2023NSCQ-mSX0561(to WL).
文摘Effective treatment methods for stroke,a common cerebrovascular disease with a high mortality rate,are still being sought.Exosome therapy,a form of acellular therapy,has demonstrated promising efficacy in various diseases in animal models;however,there is currently insufficient evidence to guide the clinical application of exosome in patients with stroke.This article reviews the progress of exosome applications in stroke treatment.It aims to elucidate the significant potential value of exosomes in stroke therapy and provide a reference for their clinical translation.At present,many studies on exosome-based therapies for stroke are actively underway.Regarding preclinical research,exosomes,as bioactive substances with diverse sources,currently favor stem cells as their origin.Due to their high plasticity,exosomes can be effectively modified through various physical,chemical,and genetic engineering methods to enhance their efficacy.In animal models of stroke,exosome therapy can reduce neuroinflammatory responses,alleviate oxidative stress damage,and inhibit programmed cell death.Additionally,exosomes can promote angiogenesis,repair and regenerate damaged white matter fiber bundles,and facilitate the migration and differentiation of neural stem cells,aiding the repair process.We also summarize new directions for the application of exosomes,specifically the exosome intervention through the ventricular-meningeal lymphatic system.The review findings suggest that the treatment paradigm for stroke is poised for transformation.
基金supported by the National Natural Science Foundation of China under Grant 62171233the Natural Science Foundation of China,Jiangsu Province under Grant BK20241891the Jiangsu Province Graduate Research and Practice Innovation Plan under Grants SJCX24_0313 and KYCX24_1169。
文摘A high-sensitivity,low-noise single photon avalanche diode(SPAD)detector was presented based on a 180 nm BCD process.The proposed device utilizes a p-implant layer/high-voltage n-well(HVNW)junction to form a deep avalanche multiplication region for near-infrared(NIR)sensitivity enhancement.By optimizing the device size and electric field of the guard ring,the fill factor(FF)is significantly improved,further increasing photon detection efficiency(PDE).To solve the dark noise caused by the increasing active diameter,a field polysilicon gate structure connected to the p+anode was investigated,effectively suppressing dark count noise by 76.6%.It is experimentally shown that when the active diameter increases from 5 to 10μm,the FF is significantly improved from 20.7%to 39.1%,and thus the peak PDE also rises from 13.3%to 25.8%.At an excess bias voltage of 5 V,a NIR photon detection probability(PDP)of 6.8%at 905 nm,a dark count rate(DCR)of 2.12 cps/μm^(2),an afterpulsing probability(AP)of 1.2%,and a timing jitter of 216 ps are achieved,demonstrating excellent single photon detection performance.
基金supported by the National Health and Family Planning Commission of China (201302002 ClinicalTrials.gov Number NCT 02200679)
文摘The Autism Spectrum Rating Scale(ASRS) and the Social Responsiveness Scale(SRS) have been widely used for screening autism spectrum disorder(ASD) in the general population during epidemiological studies, but studies of individuals with intellectual disability(ID) are quite limited. Therefore, we recruited the parents/caregivers of 204 ASD cases, 71 ID cases aged 6–18 years from special education schools, and 402 typically developing(TD) children in the same age span from a communitybased population to complete the ASRS and SRS. The results showed that the ID group scored significantly lower on total and subscale scores than the ASD group on both scales(P \ 0.05) but higher than TD children(P \ 0.05).Receiver operating characteristic analyses demonstrated a similar fair performance in discriminating ASD from ID with the ASRS(area under the curve(AUC) = 0.709,sensitivity = 77.0%, specificity = 52.1%, positive predictive value(PPV) = 82.2%) and the SRS(AUC = 0.742,sensitivity = 59.8%, specificity = 77.5%, PPV = 88.4%).The results showed that individuals with ID had clear autistic traits and discriminating ASD from ID cases was quite challenging, while assessment tools such as ASRS and SRS, help to some degree.
基金the National Natural Science Foundation of China(Research of the Biological Effects and Mechanism of Different Guasha Therapies,No.30672720)the National Natural Science Foundation of China(Comparative Research of Different Acupuncture Stimulation Methods on The Expression of Effects in Acupoint Areas,No.81674079)
文摘OBJECTIVE: To evaluate the effects of Guasha therapy on the rating of perceived exertion(RPE) scale score, and heart rate variability(HRV).METHODS: A randomized controlled trial of Guasha(skin scraping) was compared with a sham scraping group and control group. Sixteen sessions within an 8-week period were completed. Sixty-five male weightlifters who had undergone normal weightlifting training for a mean of 5 years before study commencement were recruited. The RPEscale score of "snatch", "clean and jerk" maneuvers(85% of one-repetition maximum), and HRV were measured before and after the intervention.RESULTS: The RPE scale score for snatch, clean and jerk were reduced significantly after intervention in the Guasha group and sham group. However, there was a significant difference in the low frequency(LF) domain and LF/high frequency(HF) ratio(P <0.05): the LF domain decreased, and the LF/HF ratio decreased.CONCLUSION: Guasha could be used to reduce the RPE scale score, and increase the response to HRV.Guasha could be considered as an alternative to some types of recovery from sports training.
文摘Rock mass classification systems are the very important part for underground projects and rock mass rating(RMR) is one of the most commonly applied classification systems in numerous civil and mining projects. The type of rock mass consisting of an interbedding of strong and weak layers poses difficulties and uncertainties for determining the RMR. For this, the present paper uses the concept of rock bolt supporting factor(RSF) for modification of RMR system to be used in such rock mass types. The proposed method also demonstrates the importance of rock bolting practice in such rock masses. The geological parameters of the Shemshak Formation of the Alborz Tunnel in Iran are used as case examples for development of the theoretical approach.
基金supported by the National Health and Family Planning Commission of China(201302002)the National Natural Science Foundation of China(81371270Clinical Trials.gov number NCT 02200679)
文摘The reported prevalence of autism spectrum disorder（ASD） has been increasing rapidly in many parts of the world. However, data on its prevalence in China are largely missing. Here, we assessed the suitability of the modi？ed Chinese version of a newly-developed ASD screening tool, the Modi？ed Chinese Autism Spectrum Rating Scales（MC-ASRS） in screening for ASD in Chi nese children aged 6–12 years, through comparison with the Social Responsiveness Scale（SRS） that has been widely used for ASD screening. We recruited the par ents/caregivers of 1588 typically-developing children and190 children with ASD aged 6–12 years to complete the MC-ASRS and SRS, and evaluated the validity of both scales in discriminating children with ASD from those developing typically. The results showed that MC-ASRSperformed as well as SRS in sensitivity, speci？city, and area-under-the-curve（both [0.95） in receiver operating characteristic analysis, with a fair false-negative rate.These results suggest that MC-ASRS is a promising tool for screening for children with ASD in the general Chinese population.
基金Project supported by the National Natural Science Foundation of China (No. 40101013) the Outstanding Overseas Chinese Scholars Fund of the Chinese Academy of Sciences (No. 2003-1-7).
文摘Comparisons of red ratings (RR) with Fe_d, Fe_d/Fet, clay content, andmagnetic susceptibility (x) of two loess-paleosol sequences at Luochuan and Lingtai on China's LoessPlateau were conducted to study the possible relationship between RR and pedogenic degrees of thetwo loess-paleosol sequences, and to discuss whether the RR could become new paleo-climaticindicators. Results showed that the RR of the two loess-paleosol sequences had positive, highlysignificant (P < 0.01) correlations with: 1) citrate-bicarbonate-dithionite (CBD) extracted iron(Fe_d), 2) ratios of CBD extracted iron to total iron (Fe_d/Fet), 3) clay (< 2 mum), and 4) magneticsusceptibility (x). This suggested that the RR of these loess-paleosol sequences could indicatedegreesof loess weathering and pedogenesis and were potential paleo-climatic proxies. The strongcorrelations of RR to Fe_d and x also implied that during pedogenic processes, pedogenic hematite inloess and paleosols were closely related to the amount of total secondary iron oxides and pedogenicferrimagnetic minerals (predominantly maghemite).
文摘In order to design the relief system size of di-tert-butyl peroxide(DTBP) storage tanks,the runaway re-action of DTBP was simulated by accelerating rate calorimeter(ARC).The results indicated that under adiabatic conditions the initial exothermic temperature was 102.6 ℃,the maximum self-heating rate was 3.095×107 ℃·min-1,the maximum self-heating temperature was 375.9 ℃,and the pressure produced by unit mass was 4.512 MPa·g-1.Judged by ARC test,the emergency relief system for DTBP was a hybrid system.Based on Design Institute for Emergency Relief System(DIERS) method,the releasing mass flow rate W was determined by Leung methods,and the mass velocity G was calculated by two modified Omega methods.The two relief sizes calculated by monograph Omega method and arithmetic Omega method are close,with only 0.63% relative error.The monograph Omega method is more convenient to apply.
文摘BACKGROUND Autism is the most common clinical developmental disorder in children.The childhood autism rating scale(CARS)and autistic autism behavior checklist(ABC)are the most commonly used assessment scales for diagnosing autism.However,the diagnostic validations and the corresponding cutoffs for CARS and ABC in individuals with suspected autism spectrum disorder(ASD)remain unclear.Furthermore,for suspected ASD in China,it remains unclear whether CARS is a better diagnostic tool than ABC.Also unclear is whether the current cutoff points for ABC and CARS are suitable for the accurate diagnosis of ASD.AIM To investigate the diagnostic validity of CARS and ABC based on a large Chinese sample.METHODS A total of 591 outpatient children from the ASD Unit at Beijing Children’s Hospital between June and November 2019 were identified.First,the Clancy autism behavior scale(CABS)was used to screen out suspected autism from these children.Then,each suspected ASD was evaluated by CARS and ABC.Receiver operating characteristic(ROC)curve analysis was used to compare diagnostic validations.We also calculated the area under the curve(AUC)for both CARS and ABC.RESULTS We found that the Cronbach alpha coefficients of CARS and ABC were 0.772 and 0.426,respectively.Therefore,the reliability of the CARS was higher than that of the ABC.In addition,we found that the correlation between CARS and CABS was 0.732.Next,we performed ROC curve analysis for CARS and ABC,which yielded AUC values of 0.846 and 0.768,respectively.The cutoff value,which is associated with the maximum Youden index,is usually applied as a decision threshold.We found that the cutoff values of CARS and ABC were 34 and 67,respectively.CONCLUSION This result indicated that CARS is superior to ABC in the Chinese population with suspected ASD.
