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HPLC-ESI-MS/MS同时测定松萝中3种酚酸类成分的含量 被引量:2
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作者 马英华 田婷婷 +4 位作者 解伟伟 靳怡然 许慧君 张兰桐 杜英峰 《中国中药杂志》 CAS CSCD 北大核心 2015年第24期4884-4889,共6页
建立高效液相色谱串联质谱法(HPLC-ESI-MS/MS)同时测定松萝中松萝酸、地弗地衣酸、拉马酸3种主要有效成分的含量。采用Agilent ZORBAX SB-C18色谱柱(4.6 mm×250 mm,5μm),流动相为甲醇(0.05%甲酸)-水(0.05%甲酸-4 mmol乙酸铵),等... 建立高效液相色谱串联质谱法(HPLC-ESI-MS/MS)同时测定松萝中松萝酸、地弗地衣酸、拉马酸3种主要有效成分的含量。采用Agilent ZORBAX SB-C18色谱柱(4.6 mm×250 mm,5μm),流动相为甲醇(0.05%甲酸)-水(0.05%甲酸-4 mmol乙酸铵),等度洗脱,流速0.8 m L·min^(-1)。采用正负离子切换模式,多反应监测(MRM)进行定量测定,在负离子条件下测定松萝酸和地弗地衣酸,在正离子条件下测定拉马酸。结果上述3种主要成分在进样量范围内呈良好线性(r>0.997 9);平均回收率为95.0%~105.1%,RSD为1.1%~5.2%。该方法简便、快速、准确、重复性好,为综合评价松萝的质量提供参考。 展开更多
关键词 松萝 液相色谱-串联质谱 松萝酸 地弗地衣酸 拉马酸 定量
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Changes of Transverse Mandibular Width in Set-Back Mandibular Surgery: Sagittal Split versus Intraoral Verticosagittal Osteotomy
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作者 Farnoosh Razmara Hamid Mahmoodhashemi +1 位作者 Shohreh Zahraei Ali Mahmoudhashemi 《International Journal of Clinical Medicine》 2018年第5期400-407,共8页
Aim: This study was performed to evaluate the movement of the proximal segment following different methods of ramus osteotomy that is one of the side effects of orthognathic surgery. Theoretically, with intraoral vert... Aim: This study was performed to evaluate the movement of the proximal segment following different methods of ramus osteotomy that is one of the side effects of orthognathic surgery. Theoretically, with intraoral verticosagittal ramus osteotomy, it can minimize the movement of the proximal segment. The changes in the intergonal distance of mandible and the angle of the ramus flaring in two methods of osteotomy have been compared in this study. Materials and Methods: In this randomized clinical trial, included 60 patients (32 males) with mandibular prognathism and without any asymmetry were selected and divided into two groups (n = 30). One group underwent bilateral sagittal split ramus osteotomy technique to achieve mandibular setback and the other by the intraoral verticosagittal ramus osteotomy technique. Intergonial width and inner-ramal angle in the transverse plane were measured on radiographs preoperatively and 1 and 12 weeks postoperatively. Data were analyzed using covariance test with the significance level set at P 0.1). Conclusion: Considering our findings, there was no significant difference between two ramus osteotomy techniques regarding changes in mandibular width and inter-ramal flaring angle. 展开更多
关键词 Bilateral SAGITTAL SPLIT Ramus OSTEOTOMY (BSSRO) INTRAORAL Verticosagittal Ramus OSTEOTOMY (IVSRO) Intergonial WIDTH MANDIBULAR Prognathism Inter ramal Angle
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